Rattus norvegicus

123 known processes

Apln

apelin

(Aliases: Apel)

Apln biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell proliferationGO:00421273590.120
apoptotic processGO:00069153810.114
positive regulation of cell deathGO:00109421840.113
positive regulation of programmed cell deathGO:00430681570.095
regulation of molecular functionGO:00650093980.090
programmed cell deathGO:00125013920.089
macromolecular complex subunit organizationGO:00439333390.086
cellular component assemblyGO:00226073600.081
protein complex assemblyGO:00064612630.081
organic substance catabolic processGO:19015753160.079
cellular component biogenesisGO:00440853680.079
positive regulation of nitrogen compound metabolic processGO:00511733340.076
cellular calcium ion homeostasisGO:00068741600.073
regulation of programmed cell deathGO:00430673410.073
regulation of apoptotic processGO:00429813350.068
response to hypoxiaGO:00016662310.065
regulation of transcription dna templatedGO:00063553740.064
homeostatic processGO:00425923310.064
positive regulation of apoptotic processGO:00430651540.064
purine nucleoside triphosphate metabolic processGO:00091441410.058
catabolic processGO:00090563510.056
cell cell signalingGO:00072673350.056
response to woundingGO:00096112540.056
organelle organizationGO:00069962660.055
cellular ion homeostasisGO:00068731840.054
metal ion homeostasisGO:00550651860.054
protein complex biogenesisGO:00702712630.053
response to inorganic substanceGO:00100353770.053
protein complex subunit organizationGO:00718223020.052
regulation of catalytic activityGO:00507903040.052
nucleobase containing small molecule metabolic processGO:00550863160.052
cellular response to oxygen containing compoundGO:19017013860.052
macromolecular complex assemblyGO:00650032730.051
ribose phosphate metabolic processGO:00196932350.051
protein localizationGO:00081041910.050
response to glucocorticoidGO:00513842230.050
positive regulation of nucleobase containing compound metabolic processGO:00459353190.049
secretionGO:00469033070.049
negative regulation of response to stimulusGO:00485851550.047
rna metabolic processGO:00160704060.047
nucleoside metabolic processGO:00091161790.047
response to decreased oxygen levelsGO:00362932370.046
regulation of phosphorus metabolic processGO:00511743490.046
cellular catabolic processGO:00442482950.046
regulation of cellular localizationGO:00603412630.046
central nervous system developmentGO:00074173110.045
brain developmentGO:00074202470.045
carbohydrate derivative catabolic processGO:19011361470.045
anatomical structure morphogenesisGO:00096532980.045
g protein coupled receptor signaling pathwayGO:00071862420.045
positive regulation of phosphate metabolic processGO:00459372620.044
neuron projection developmentGO:00311752730.044
response to oxygen levelsGO:00704822650.044
regulation of multicellular organismal developmentGO:20000263760.043
establishment of protein localizationGO:00451841410.043
organophosphate metabolic processGO:00196373700.042
positive regulation of transcription dna templatedGO:00458931970.042
anion transportGO:00068201780.041
purine ribonucleotide catabolic processGO:00091541360.041
positive regulation of biosynthetic processGO:00098913190.040
carbohydrate derivative metabolic processGO:19011353460.040
response to estradiolGO:00323551640.040
cellular metal ion homeostasisGO:00068751720.040
chemical homeostasisGO:00488782920.039
oxoacid metabolic processGO:00434362900.039
regulation of phosphate metabolic processGO:00192203490.039
ribonucleotide metabolic processGO:00092592310.039
response to corticosteroidGO:00319602350.038
neuron developmentGO:00486662860.038
wound healingGO:00420601220.038
nucleic acid templated transcriptionGO:00976593790.038
nucleotide catabolic processGO:00091661390.038
organophosphate catabolic processGO:00464341480.037
transcription dna templatedGO:00063513770.037
protein phosphorylationGO:00064683450.037
protein oligomerizationGO:00512591910.037
reproductive processGO:00224143720.037
multi organism reproductive processGO:00447032620.037
cellular chemical homeostasisGO:00550822470.037
nucleoside catabolic processGO:00091641260.037
negative regulation of metabolic processGO:00098923310.036
intracellular signal transductionGO:00355563140.036
negative regulation of cell communicationGO:00106481580.035
purine nucleoside triphosphate catabolic processGO:00091461220.035
single organism catabolic processGO:00447122830.035
multi multicellular organism processGO:00447061380.035
rna biosynthetic processGO:00327743800.035
organonitrogen compound catabolic processGO:19015651790.034
cation transportGO:00068123820.034
response to nutrient levelsGO:00316673700.034
response to peptide hormoneGO:00434342780.034
regulation of cell differentiationGO:00455953200.034
purine ribonucleotide metabolic processGO:00091502270.034
ribonucleoside metabolic processGO:00091191740.033
negative regulation of signalingGO:00230571570.033
nucleoside triphosphate metabolic processGO:00091411440.033
heterocycle catabolic processGO:00467001670.033
regulation of system processGO:00440572080.033
regulation of response to stressGO:00801341260.033
head developmentGO:00603222470.033
monovalent inorganic cation transportGO:00156721720.033
nucleobase containing compound catabolic processGO:00346551520.032
nucleotide metabolic processGO:00091172790.032
purine ribonucleoside triphosphate metabolic processGO:00092051400.032
potassium ion transportGO:0006813970.032
calcium ion homeostasisGO:00550741620.032
nitrogen compound transportGO:00717052290.032
protein transportGO:00150311320.031
cellular nitrogen compound catabolic processGO:00442701630.031
response to metal ionGO:00100382530.031
regulation of anatomical structure sizeGO:00900661350.031
cell projection organizationGO:00300303020.031
positive regulation of phosphorus metabolic processGO:00105622620.031
cytoskeleton organizationGO:00070101110.031
glycosyl compound metabolic processGO:19016571820.031
positive regulation of cell proliferationGO:00082842490.030
regulation of cellular ketone metabolic processGO:0010565270.030
ribonucleotide catabolic processGO:00092611360.030
ribonucleoside triphosphate catabolic processGO:00092031220.030
cellular amine metabolic processGO:0044106380.029
ribonucleoside catabolic processGO:00424541260.029
single organism organelle organizationGO:19025891800.029
cation homeostasisGO:00550801950.029
positive regulation of nucleic acid templated transcriptionGO:19035081970.028
purine nucleotide catabolic processGO:00061951360.028
purine ribonucleoside metabolic processGO:00461281680.028
neurological system processGO:00508772190.028
regulation of cellular component organizationGO:00511283680.028
ion homeostasisGO:00508012120.028
purine ribonucleoside triphosphate catabolic processGO:00092071220.028
purine nucleoside metabolic processGO:00422781690.027
organic acid metabolic processGO:00060822920.027
purine containing compound metabolic processGO:00725212530.027
cellular homeostasisGO:00197252520.027
positive regulation of gene expressionGO:00106282440.027
positive regulation of rna metabolic processGO:00512542030.027
positive regulation of catalytic activityGO:00430851840.026
response to extracellular stimulusGO:00099913800.026
amine metabolic processGO:0009308380.026
positive regulation of multicellular organismal processGO:00512403870.026
cellular response to endogenous stimulusGO:00714953770.026
positive regulation of cellular component organizationGO:00511302000.026
regulation of tube sizeGO:0035150890.026
female pregnancyGO:00075651220.026
positive regulation of hydrolase activityGO:0051345860.026
regulation of phosphorylationGO:00423252480.026
response to oxidative stressGO:00069791860.025
regulation of defense responseGO:0031347680.025
transmembrane transportGO:00550854120.025
regulation of cellular amino acid metabolic processGO:000652120.025
regulation of potassium ion transportGO:0043266290.025
actin filament based processGO:0030029860.025
regulation of secretion by cellGO:19035302080.025
regulation of membrane potentialGO:00423911100.025
circulatory system processGO:00030131830.024
cytosolic calcium ion homeostasisGO:00514801400.024
regulation of nucleic acid templated transcriptionGO:19035063800.024
purine nucleotide metabolic processGO:00061632290.024
neuron differentiationGO:00301823680.024
positive regulation of molecular functionGO:00440932300.024
purine containing compound catabolic processGO:00725231380.024
regulation of blood vessel sizeGO:0050880890.023
cellular ketone metabolic processGO:0042180510.023
nucleoside phosphate metabolic processGO:00067532830.023
positive regulation of rna biosynthetic processGO:19026801970.023
inflammatory responseGO:00069541500.023
divalent inorganic cation homeostasisGO:00725071650.023
divalent metal ion transportGO:00708381320.023
negative regulation of phosphorus metabolic processGO:0010563800.023
negative regulation of molecular functionGO:00440921330.023
action potentialGO:0001508540.023
purine ribonucleoside catabolic processGO:00461301240.023
response to peptideGO:19016522920.023
guanosine containing compound catabolic processGO:1901069710.023
organic cyclic compound catabolic processGO:19013611750.023
lipid metabolic processGO:00066292830.023
response to nicotineGO:0035094510.023
negative regulation of macromolecule metabolic processGO:00106052600.023
regulation of nervous system developmentGO:00519602640.022
regulation of ion transportGO:00432692450.022
aromatic compound catabolic processGO:00194391680.022
oxidation reduction processGO:00551143040.022
carboxylic acid metabolic processGO:00197522890.022
regulation of cellular protein metabolic processGO:00322682670.022
ion transmembrane transportGO:00342203650.022
circulatory system developmentGO:00723591340.022
positive regulation of phosphorylationGO:00423271770.022
negative regulation of cellular metabolic processGO:00313242810.022
regulation of cellular component biogenesisGO:0044087860.021
cardiovascular system developmentGO:00723581340.021
nucleoside phosphate catabolic processGO:19012921400.021
synaptic transmissionGO:00072682350.021
cellular divalent inorganic cation homeostasisGO:00725031620.021
response to mechanical stimulusGO:00096121340.021
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.021
positive regulation of transportGO:00510502450.021
response to nutrientGO:00075842480.021
purine nucleoside catabolic processGO:00061521240.021
regulation of locomotionGO:00400121480.021
positive regulation of signalingGO:00230562700.021
regulation of hydrolase activityGO:00513361430.021
regulation of nucleoside metabolic processGO:0009118660.021
regenerationGO:00310991630.021
regulation of cellular amine metabolic processGO:003323880.020
cellular cation homeostasisGO:00300031800.020
nucleoside triphosphate catabolic processGO:00091431230.020
muscle system processGO:00030121150.020
response to alkaloidGO:00432791320.020
immune system processGO:00023762040.020
glycosyl compound catabolic processGO:19016581260.020
positive regulation of response to stimulusGO:00485842850.020
cellular lipid metabolic processGO:00442552080.020
regulation of secretionGO:00510462240.019
regulation of nucleotide catabolic processGO:0030811650.019
positive regulation of protein metabolic processGO:00512471780.019
regulation of protein metabolic processGO:00512462890.019
metal ion transportGO:00300012890.019
regulation of rna biosynthetic processGO:20011413810.019
defense responseGO:00069521940.019
cellular macromolecule localizationGO:00707271220.019
organic anion transportGO:00157111320.019
cell adhesionGO:00071551100.019
cellular component movementGO:00069282480.019
regulation of immune system processGO:00026821230.019
sensory perception of painGO:0019233730.019
locomotionGO:00400112370.018
transcription from rna polymerase ii promoterGO:00063662520.018
regulation of purine nucleotide metabolic processGO:19005421150.018
cellular amino acid metabolic processGO:00065201070.018
negative regulation of nucleic acid templated transcriptionGO:19035071170.018
single organism intracellular transportGO:19025821660.018
regulation of intracellular signal transductionGO:19025312180.018
regulation of response to external stimulusGO:00321011060.018
regulation of transcription from rna polymerase ii promoterGO:00063572340.018
negative regulation of signal transductionGO:0009968830.018
reproductionGO:00000032450.017
positive regulation of developmental processGO:00510942830.017
regulation of catabolic processGO:00098941130.017
regulation of blood circulationGO:19035221100.017
carboxylic acid transportGO:00469421150.017
regulation of organelle organizationGO:0033043800.017
cellular protein localizationGO:00346131220.017
regulation of neuron projection developmentGO:00109751610.017
intracellular protein transportGO:0006886790.017
monocarboxylic acid metabolic processGO:00327871520.017
cellular response to stressGO:00335542690.017
peptide secretionGO:0002790860.017
regulation of signal transductionGO:00099663180.017
cellular response to organic cyclic compoundGO:00714072020.017
regulation of anatomical structure morphogenesisGO:00226031410.017
macromolecule localizationGO:00330362520.017
positive regulation of macromolecule biosynthetic processGO:00105572470.017
cellular response to lipidGO:00713962010.017
positive regulation of cytosolic calcium ion concentrationGO:00072041220.017
vascular process in circulatory systemGO:0003018960.017
response to temperature stimulusGO:0009266940.016
regulation of rna metabolic processGO:00512523910.016
regulation of cellular catabolic processGO:00313291010.016
neuronal action potentialGO:0019228350.016
biological adhesionGO:00226101100.016
proteolysisGO:00065081750.016
heart contractionGO:0060047570.016
response to carbohydrateGO:00097431830.016
cation transmembrane transportGO:00986552630.016
response to radiationGO:00093141370.016
blood vessel morphogenesisGO:0048514580.016
ribonucleoside triphosphate metabolic processGO:00091991410.016
regulation of protein phosphorylationGO:00019321830.016
positive regulation of cellular protein metabolic processGO:00322701670.016
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.016
regulation of protein transportGO:0051223680.016
negative regulation of apoptotic processGO:00430661810.016
single organism biosynthetic processGO:00447113420.016
peptidyl amino acid modificationGO:00181931260.016
ras protein signal transductionGO:0007265290.016
anterior posterior pattern specificationGO:000995210.016
positive regulation of cell communicationGO:00106472710.016
response to growth factorGO:00708481890.016
hormone secretionGO:00468791150.016
intracellular transportGO:00469071850.016
regulation of neuron differentiationGO:00456642080.015
eye morphogenesisGO:004859240.015
positive regulation of purine nucleotide catabolic processGO:0033123530.015
signal releaseGO:00230611450.015
positive regulation of cell differentiationGO:00455972170.015
organ morphogenesisGO:0009887750.015
regulation of neurogenesisGO:00507672470.015
regulation of peptide hormone secretionGO:0090276800.015
cell type specific apoptotic processGO:00972851340.015
heart morphogenesisGO:000300730.015
small gtpase mediated signal transductionGO:0007264360.015
gtp catabolic processGO:0006184710.015
organic acid transportGO:00158491160.015
protein heterooligomerizationGO:0051291890.015
regulation of synaptic transmissionGO:00508041410.015
negative regulation of nucleobase containing compound metabolic processGO:00459341530.015
anatomical structure formation involved in morphogenesisGO:0048646830.015
positive regulation of purine nucleotide metabolic processGO:1900544910.015
positive regulation of nervous system developmentGO:00519621780.015
regulation of nucleotide metabolic processGO:00061401170.015
cellular response to growth factor stimulusGO:00713631620.014
regulation of protein modification processGO:00313991940.014
cell morphogenesisGO:00009021420.014
regulation of protein localizationGO:0032880810.014
carbohydrate metabolic processGO:00059751300.014
amide transportGO:00428861050.014
negative regulation of biosynthetic processGO:00098901680.014
positive regulation of cellular catabolic processGO:0031331710.014
secretion by cellGO:00329402480.014
regulation of mapk cascadeGO:00434081160.014
multicellular organismal reproductive processGO:00486092330.014
response to hexoseGO:00097461440.014
regulation of cytoskeleton organizationGO:0051493490.014
fatty acid metabolic processGO:0006631990.014
positive regulation of mapk cascadeGO:0043410920.014
positive regulation of ion transportGO:0043270940.014
axis specificationGO:000979840.014
negative regulation of cell deathGO:00605482290.014
negative regulation of gene expressionGO:00106291990.014
positive regulation of cellular component biogenesisGO:0044089550.014
regulation of cell developmentGO:00602842630.014
muscle cell proliferationGO:0033002840.013
regulation of establishment of protein localizationGO:0070201690.013
agingGO:00075682410.013
positive regulation of secretionGO:00510471400.013
cellular response to external stimulusGO:00714961180.013
positive regulation of gtpase activityGO:0043547470.013
negative regulation of phosphorylationGO:0042326570.013
response to monosaccharideGO:00342841590.013
regulation of peptide transportGO:0090087870.013
transmission of nerve impulseGO:0019226420.013
positive regulation of protein modification processGO:00314011420.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
guanosine containing compound metabolic processGO:1901068740.013
motor neuron axon guidanceGO:000804510.013
non canonical wnt signaling pathwayGO:003556730.013
cellular protein complex assemblyGO:0043623440.013
positive regulation of nucleotide metabolic processGO:0045981910.013
regulation of inflammatory responseGO:0050727480.013
regulation of neurological system processGO:0031644430.013
cellular response to hormone stimulusGO:00328702470.013
actin cytoskeleton organizationGO:0030036730.013
renal system developmentGO:0072001670.013
rho protein signal transductionGO:0007266110.013
cellular response to organonitrogen compoundGO:00714171970.013
negative regulation of cell proliferationGO:00082851190.013
sensory perceptionGO:00076001010.013
cellular response to mechanical stimulusGO:0071260480.013
unsaturated fatty acid metabolic processGO:0033559390.013
positive regulation of cellular amine metabolic processGO:003324030.012
behaviorGO:00076102050.012
regulation of canonical wnt signaling pathwayGO:006082840.012
cellular component morphogenesisGO:00329891550.012
cell cycle checkpointGO:000007520.012
l glutamate importGO:005193820.012
negative regulation of phosphate metabolic processGO:0045936800.012
neuromuscular processGO:005090520.012
positive regulation of cellular biosynthetic processGO:00313282950.012
response to ethanolGO:00454711620.012
regulation of hormone levelsGO:00108171870.012
positive regulation of cell developmentGO:00107201760.012
regulation of kinase activityGO:00435491170.012
positive regulation of blood circulationGO:1903524650.012
response to bacteriumGO:00096172000.012
regulation of response to woundingGO:1903034690.012
regulation of synaptic plasticityGO:0048167700.012
regulation of metal ion transportGO:00109591180.012
regulation of muscle system processGO:0090257790.012
gtp metabolic processGO:0046039720.012
cellular response to nitrogen compoundGO:19016992100.012
response to acid chemicalGO:00011012220.012
tissue remodelingGO:0048771400.012
positive regulation of gtp catabolic processGO:0033126480.012
negative regulation of cellular biosynthetic processGO:00313271610.012
cellular response to steroid hormone stimulusGO:0071383930.012
negative regulation of vascular permeabilityGO:004311630.012
peptide transportGO:0015833970.011
negative regulation of multicellular organismal processGO:00512412030.011
response to reactive oxygen speciesGO:00003021200.011
positive regulation of nucleotide catabolic processGO:0030813530.011
localization of cellGO:00516742020.011
positive regulation of protein phosphorylationGO:00019341350.011
regulation of hormone secretionGO:00468831060.011
growthGO:00400071650.011
regulation of sensory perception of painGO:0051930290.011
defense response to gram negative bacteriumGO:005082930.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.011
single organismal cell cell adhesionGO:0016337420.011
regulation of cell migrationGO:00303341280.011
response to ketoneGO:19016541820.011
negative regulation of innate immune responseGO:004582440.011
calcium ion transportGO:00068161310.011
gamete generationGO:00072761240.011
single organism reproductive processGO:00447022970.011
reactive nitrogen species metabolic processGO:200105710.011
negative regulation of transportGO:00510511360.011
muscle structure developmentGO:0061061870.011
negative regulation of catalytic activityGO:00430861030.011
negative regulation of protein phosphorylationGO:0001933440.011
cytoplasmic transportGO:00164821150.011
negative regulation of programmed cell deathGO:00430691830.011
generation of precursor metabolites and energyGO:0006091620.011
response to insulinGO:00328681330.011
peptide hormone secretionGO:0030072840.011
respiratory gaseous exchangeGO:000758540.011
membrane hyperpolarizationGO:0060081110.011
response to transition metal nanoparticleGO:19902671220.011
tissue developmentGO:00098882520.010
cellular response to oxygen levelsGO:0071453600.010
organic hydroxy compound metabolic processGO:19016151150.010
insulin secretionGO:0030073690.010
organic hydroxy compound transportGO:0015850770.010
response to glucoseGO:00097491360.010
ribonucleoside monophosphate metabolic processGO:0009161880.010
response to vitaminGO:00332731310.010
positive regulation of catabolic processGO:0009896780.010
amino acid transportGO:0006865700.010
cellular response to peptideGO:19016531330.010
angiogenesisGO:0001525530.010
regulation of calcium ion transportGO:0051924770.010
vesicle mediated transportGO:00161921810.010
positive regulation of secretion by cellGO:19035321280.010

Apln disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.047
disease of anatomical entityDOID:700.047
sensory system diseaseDOID:005015500.047
eye diseaseDOID:561400.047
retinal diseaseDOID:567900.047
eye and adnexa diseaseDOID:149200.047
disease of metabolismDOID:001466700.020
inherited metabolic disorderDOID:65500.011