IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Rpp40

ribonuclease P 40 subunit (human)

(Aliases: MGC108849)

Entrez: 291071
RGD: 1310228
Ensembl: ENSRNOG00000016226
UniProtKB: Q5BK64

Process Predictions
Disease Predictions

Rpp40 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
single organism biosynthetic process	GO:0044711	342	0.109
cellular catabolic process	GO:0044248	295	0.067
organic substance catabolic process	GO:1901575	316	0.058
glycosyl compound catabolic process	GO:1901658	126	0.052
regulation of molecular function	GO:0065009	398	0.048
carbohydrate derivative metabolic process	GO:1901135	346	0.048
organonitrogen compound catabolic process	GO:1901565	179	0.047
purine containing compound catabolic process	GO:0072523	138	0.046
catabolic process	GO:0009056	351	0.045
single organism catabolic process	GO:0044712	283	0.045
glycosyl compound metabolic process	GO:1901657	182	0.040
organophosphate metabolic process	GO:0019637	370	0.039
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.039
nucleotide metabolic process	GO:0009117	279	0.039
purine containing compound metabolic process	GO:0072521	253	0.038
nucleobase containing compound catabolic process	GO:0034655	152	0.038
ribonucleoside catabolic process	GO:0042454	126	0.037
response to inorganic substance	GO:0010035	377	0.037
intracellular signal transduction	GO:0035556	314	0.032
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.031
purine nucleotide metabolic process	GO:0006163	229	0.030
purine nucleoside catabolic process	GO:0006152	124	0.029
ribose phosphate metabolic process	GO:0019693	235	0.029
nucleoside catabolic process	GO:0009164	126	0.028
macromolecule localization	GO:0033036	252	0.028
nucleobase containing small molecule metabolic process	GO:0055086	316	0.027
carboxylic acid metabolic process	GO:0019752	289	0.027
nucleotide catabolic process	GO:0009166	139	0.027
heterocycle catabolic process	GO:0046700	167	0.027
homeostatic process	GO:0042592	331	0.026
organic cyclic compound catabolic process	GO:1901361	175	0.026
regulation of protein metabolic process	GO:0051246	289	0.025
nucleoside phosphate catabolic process	GO:1901292	140	0.025
purine ribonucleoside catabolic process	GO:0046130	124	0.025
regulation of signal transduction	GO:0009966	318	0.025
purine nucleotide catabolic process	GO:0006195	136	0.025
regulation of catalytic activity	GO:0050790	304	0.024
nucleoside metabolic process	GO:0009116	179	0.024
protein complex subunit organization	GO:0071822	302	0.024
protein oligomerization	GO:0051259	191	0.024
organic acid metabolic process	GO:0006082	292	0.024
positive regulation of molecular function	GO:0044093	230	0.024
cellular nitrogen compound catabolic process	GO:0044270	163	0.023
ion transmembrane transport	GO:0034220	365	0.023
nucleoside triphosphate metabolic process	GO:0009141	144	0.022
purine ribonucleotide metabolic process	GO:0009150	227	0.022
rna biosynthetic process	GO:0032774	380	0.022
negative regulation of cellular metabolic process	GO:0031324	281	0.022
apoptotic process	GO:0006915	381	0.022
carbohydrate derivative catabolic process	GO:1901136	147	0.022
nucleoside phosphate metabolic process	GO:0006753	283	0.022
positive regulation of response to stimulus	GO:0048584	285	0.022
ribonucleoside metabolic process	GO:0009119	174	0.021
ribonucleotide catabolic process	GO:0009261	136	0.021
nucleoside triphosphate catabolic process	GO:0009143	123	0.021
purine ribonucleotide catabolic process	GO:0009154	136	0.020
cellular lipid metabolic process	GO:0044255	208	0.020
aromatic compound catabolic process	GO:0019439	168	0.020
ribonucleotide metabolic process	GO:0009259	231	0.020
positive regulation of catalytic activity	GO:0043085	184	0.020
regulation of phosphorus metabolic process	GO:0051174	349	0.020
cellular response to stress	GO:0033554	269	0.020
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.020
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.020
organelle organization	GO:0006996	266	0.020
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.020
regulation of hydrolase activity	GO:0051336	143	0.020
purine nucleoside metabolic process	GO:0042278	169	0.020
protein localization	GO:0008104	191	0.019
reproductive process	GO:0022414	372	0.019
lipid metabolic process	GO:0006629	283	0.019
cellular amino acid metabolic process	GO:0006520	107	0.019
cellular macromolecule localization	GO:0070727	122	0.019
negative regulation of multicellular organismal process	GO:0051241	203	0.019
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.019
reproduction	GO:0000003	245	0.018
regulation of catabolic process	GO:0009894	113	0.018
single organism cellular localization	GO:1902580	102	0.017
organophosphate catabolic process	GO:0046434	148	0.017
cellular homeostasis	GO:0019725	252	0.017
cellular response to endogenous stimulus	GO:0071495	377	0.017
single organism intracellular transport	GO:1902582	166	0.017
response to biotic stimulus	GO:0009607	226	0.017
purine ribonucleoside metabolic process	GO:0046128	168	0.017
regulation of membrane potential	GO:0042391	110	0.016
cell projection organization	GO:0030030	302	0.016
growth	GO:0040007	165	0.016
cell cycle	GO:0007049	101	0.016
ion homeostasis	GO:0050801	212	0.016
regulation of cell cycle	GO:0051726	73	0.016
lipid biosynthetic process	GO:0008610	128	0.016
cellular protein localization	GO:0034613	122	0.016
rna metabolic process	GO:0016070	406	0.016
positive regulation of programmed cell death	GO:0043068	157	0.016
negative regulation of transport	GO:0051051	136	0.016
regulation of rna metabolic process	GO:0051252	391	0.016
positive regulation of cell communication	GO:0010647	271	0.016
negative regulation of macromolecule metabolic process	GO:0010605	260	0.015
ras protein signal transduction	GO:0007265	29	0.015
gtp metabolic process	GO:0046039	72	0.015
brain development	GO:0007420	247	0.015
regulation of intracellular signal transduction	GO:1902531	218	0.015
multicellular organismal reproductive process	GO:0048609	233	0.015
cellular amine metabolic process	GO:0044106	38	0.015
negative regulation of molecular function	GO:0044092	133	0.015
positive regulation of signaling	GO:0023056	270	0.015
positive regulation of cell death	GO:0010942	184	0.015
proteolysis	GO:0006508	175	0.015
oxoacid metabolic process	GO:0043436	290	0.015
response to metal ion	GO:0010038	253	0.015
positive regulation of hydrolase activity	GO:0051345	86	0.015
chemical homeostasis	GO:0048878	292	0.015
regulation of nucleotide metabolic process	GO:0006140	117	0.015
positive regulation of phosphate metabolic process	GO:0045937	262	0.015
positive regulation of developmental process	GO:0051094	283	0.015
small gtpase mediated signal transduction	GO:0007264	36	0.015
guanosine containing compound catabolic process	GO:1901069	71	0.014
regulation of cellular component organization	GO:0051128	368	0.014
regulation of cellular localization	GO:0060341	263	0.014
amine metabolic process	GO:0009308	38	0.014
protein complex biogenesis	GO:0070271	263	0.014
regulation of rna biosynthetic process	GO:2001141	381	0.014
vesicle mediated transport	GO:0016192	181	0.014
response to hypoxia	GO:0001666	231	0.014
locomotion	GO:0040011	237	0.014
single organism reproductive process	GO:0044702	297	0.013
macromolecular complex subunit organization	GO:0043933	339	0.013
central nervous system development	GO:0007417	311	0.013
regulation of apoptotic process	GO:0042981	335	0.013
response to oxygen levels	GO:0070482	265	0.013
regulation of cellular amino acid metabolic process	GO:0006521	2	0.013
positive regulation of apoptotic process	GO:0043065	154	0.013
gtp catabolic process	GO:0006184	71	0.013
guanosine containing compound metabolic process	GO:1901068	74	0.013
positive regulation of signal transduction	GO:0009967	175	0.013
regulation of purine nucleotide catabolic process	GO:0033121	65	0.013
neuron development	GO:0048666	286	0.012
response to other organism	GO:0051707	220	0.012
response to extracellular stimulus	GO:0009991	380	0.012
cytokine production	GO:0001816	61	0.012
monocarboxylic acid metabolic process	GO:0032787	152	0.012
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.012
multi organism reproductive process	GO:0044703	262	0.012
response to decreased oxygen levels	GO:0036293	237	0.012
negative regulation of metabolic process	GO:0009892	331	0.012
male gamete generation	GO:0048232	99	0.012
multicellular organism reproduction	GO:0032504	233	0.012
regulation of purine nucleotide metabolic process	GO:1900542	115	0.012
intracellular transport	GO:0046907	185	0.012
regulation of nucleic acid templated transcription	GO:1903506	380	0.012
regulation of cellular ketone metabolic process	GO:0010565	27	0.012
immune system process	GO:0002376	204	0.012
regulation of cellular amine metabolic process	GO:0033238	8	0.012
regulation of cellular protein metabolic process	GO:0032268	267	0.012
cellular chemical homeostasis	GO:0055082	247	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.012
macromolecular complex assembly	GO:0065003	273	0.011
positive regulation of catabolic process	GO:0009896	78	0.011
single organism organelle organization	GO:1902589	180	0.011
establishment of protein localization	GO:0045184	141	0.011
regulation of response to stress	GO:0080134	126	0.011
regulation of nucleoside metabolic process	GO:0009118	66	0.011
regulation of multicellular organismal development	GO:2000026	376	0.011
response to carbohydrate	GO:0009743	183	0.011
negative regulation of protein metabolic process	GO:0051248	114	0.011
regulation of cell differentiation	GO:0045595	320	0.011
transcription dna templated	GO:0006351	377	0.011
cellular response to nitrogen compound	GO:1901699	210	0.011
secretion	GO:0046903	307	0.011
protein complex assembly	GO:0006461	263	0.011
gamete generation	GO:0007276	124	0.011
regulation of programmed cell death	GO:0043067	341	0.011
sex differentiation	GO:0007548	113	0.011
positive regulation of biosynthetic process	GO:0009891	319	0.011
positive regulation of transcription dna templated	GO:0045893	197	0.011
response to external biotic stimulus	GO:0043207	221	0.011
protein phosphorylation	GO:0006468	345	0.011
rho protein signal transduction	GO:0007266	11	0.011
negative regulation of response to stimulus	GO:0048585	155	0.011
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.011
response to glucose	GO:0009749	136	0.011
organonitrogen compound biosynthetic process	GO:1901566	167	0.010
cellular response to oxygen containing compound	GO:1901701	386	0.010
developmental process involved in reproduction	GO:0003006	159	0.010
neuron differentiation	GO:0030182	368	0.010
positive regulation of phosphorus metabolic process	GO:0010562	262	0.010
negative regulation of secretion	GO:0051048	82	0.010
positive regulation of cellular amine metabolic process	GO:0033240	3	0.010
response to hexose	GO:0009746	144	0.010
blood vessel development	GO:0001568	69	0.010
negative regulation of cellular protein metabolic process	GO:0032269	106	0.010
regulation of transcription dna templated	GO:0006355	374	0.010
response to growth factor	GO:0070848	189	0.010
regulation of phosphate metabolic process	GO:0019220	349	0.010
reproductive system development	GO:0061458	128	0.010
neuron projection development	GO:0031175	273	0.010
response to monosaccharide	GO:0034284	159	0.010
negative regulation of cell death	GO:0060548	229	0.010
circulatory system process	GO:0003013	183	0.010
response to ketone	GO:1901654	182	0.010
protein homooligomerization	GO:0051260	91	0.010
erythrocyte differentiation	GO:0030218	1	0.010
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.010

Rpp40 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.014
nervous system disease	DOID:863	0.014
central nervous system disease	DOID:331	0.013

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