Rattus norvegicus

109 known processes

Grn

granulin

Grn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of protein metabolic processGO:00512462890.181
cell motilityGO:00488702020.166
regenerationGO:00310991630.158
collagen catabolic processGO:003057420.155
cellular response to endogenous stimulusGO:00714953770.145
response to peptideGO:19016522920.134
locomotionGO:00400112370.127
monovalent inorganic cation transportGO:00156721720.119
oxoacid metabolic processGO:00434362900.115
response to peptide hormoneGO:00434342780.115
positive regulation of cell migrationGO:0030335960.112
cellular component movementGO:00069282480.104
response to growth factorGO:00708481890.104
cellular catabolic processGO:00442482950.102
positive regulation of cell motilityGO:2000147970.099
cellular response to hormone stimulusGO:00328702470.097
regulation of signal transductionGO:00099663180.095
tissue developmentGO:00098882520.094
positive regulation of phosphorus metabolic processGO:00105622620.093
cellular response to organonitrogen compoundGO:00714171970.092
female pregnancyGO:00075651220.089
regulation of programmed cell deathGO:00430673410.087
protein phosphorylationGO:00064683450.087
regulation of cellular protein metabolic processGO:00322682670.081
negative regulation of response to stimulusGO:00485851550.075
glutamate receptor signaling pathwayGO:0007215430.074
regulation of cellular component movementGO:00512701500.073
amine metabolic processGO:0009308380.071
peptidyl amino acid modificationGO:00181931260.070
negative regulation of transportGO:00510511360.070
regulation of apoptotic processGO:00429813350.068
phototransduction visible lightGO:000760320.065
regulation of phosphorylationGO:00423252480.064
t cell proliferationGO:0042098190.063
negative regulation of cell deathGO:00605482290.063
carbohydrate derivative metabolic processGO:19011353460.062
response to extracellular stimulusGO:00099913800.059
multicellular organism reproductionGO:00325042330.059
programmed cell deathGO:00125013920.058
negative regulation of programmed cell deathGO:00430691830.057
response to carbohydrateGO:00097431830.057
reproductive processGO:00224143720.057
epithelium developmentGO:0060429960.056
negative regulation of cell communicationGO:00106481580.056
ion homeostasisGO:00508012120.055
positive regulation of purine nucleotide metabolic processGO:1900544910.055
regulation of sperm motilityGO:190131720.055
regulation of tolerance induction to nonself antigenGO:000265510.055
cellular response to external stimulusGO:00714961180.051
cellular amine metabolic processGO:0044106380.051
response to other organismGO:00517072200.050
positive regulation of gene expressionGO:00106282440.049
cell migrationGO:00164771970.048
regulation of locomotionGO:00400121480.047
response to nutrientGO:00075842480.045
carboxylic acid metabolic processGO:00197522890.045
regulation of cell proliferationGO:00421273590.044
response to nutrient levelsGO:00316673700.044
chemical homeostasisGO:00488782920.042
metal ion homeostasisGO:00550651860.041
cellular ketone metabolic processGO:0042180510.041
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.040
signal transduction by phosphorylationGO:00230141440.040
regulation of cellular amine metabolic processGO:003323880.040
regulation of phosphorus metabolic processGO:00511743490.039
axonogenesisGO:0007409710.039
lymphocyte activationGO:0046649430.039
regulation of tolerance induction dependent upon immune responseGO:000265210.039
proteolysisGO:00065081750.038
negative regulation of signalingGO:00230571570.038
regulation of protein modification processGO:00313991940.038
regulation of cell motilityGO:20001451310.038
positive regulation of cellular amine metabolic processGO:003324030.038
head developmentGO:00603222470.037
enzyme linked receptor protein signaling pathwayGO:00071671160.037
response to mechanical stimulusGO:00096121340.036
lens fiber cell differentiationGO:007030630.036
localization of cellGO:00516742020.036
gland developmentGO:00487321550.035
single organism catabolic processGO:00447122830.035
response to hexoseGO:00097461440.033
response to purine containing compoundGO:00140741260.033
regulation of catalytic activityGO:00507903040.033
morphogenesis of an epitheliumGO:0002009200.032
response to decreased oxygen levelsGO:00362932370.032
catabolic processGO:00090563510.032
regulation of cellular ketone metabolic processGO:0010565270.032
regulation of cellular amino acid metabolic processGO:000652120.032
epithelial cell migrationGO:0010631190.031
organic substance catabolic processGO:19015753160.031
ribose phosphate metabolic processGO:00196932350.031
multi multicellular organism processGO:00447061380.030
detection of visible lightGO:000958430.030
growthGO:00400071650.029
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.029
regulation of cell migrationGO:00303341280.028
cellular response to growth factor stimulusGO:00713631620.027
response to monosaccharideGO:00342841590.027
g protein coupled receptor signaling pathwayGO:00071862420.027
carbohydrate derivative catabolic processGO:19011361470.026
nucleotide metabolic processGO:00091172790.026
regulation of mononuclear cell proliferationGO:0032944260.026
cell morphogenesis involved in differentiationGO:00009041190.025
response to corticosteroidGO:00319602350.025
regulation of cellular localizationGO:00603412630.025
organic acid metabolic processGO:00060822920.025
response to estrogenGO:00436272320.025
regulation of immune system processGO:00026821230.025
epithelial cell differentiationGO:0030855710.024
negative regulation of apoptotic processGO:00430661810.024
cell activationGO:0001775970.024
positive regulation of cellular component movementGO:00512721020.024
regulation of phosphate metabolic processGO:00192203490.023
response to acid chemicalGO:00011012220.023
cation homeostasisGO:00550801950.023
peptidyl tyrosine phosphorylationGO:0018108720.023
homeostatic processGO:00425923310.022
positive regulation of cell projection organizationGO:00313461110.022
positive regulation of locomotionGO:00400171020.022
positive regulation of cellular protein metabolic processGO:00322701670.022
monocarboxylic acid metabolic processGO:00327871520.022
vesicle mediated transportGO:00161921810.022
response to reactive oxygen speciesGO:00003021200.022
positive regulation of multicellular organismal processGO:00512403870.021
positive regulation of protein metabolic processGO:00512471780.021
response to interleukin 1GO:0070555550.021
negative regulation of cell proliferationGO:00082851190.020
nucleoside phosphate metabolic processGO:00067532830.020
organophosphate metabolic processGO:00196373700.020
response to amineGO:0014075460.020
regulation of molecular functionGO:00650093980.020
tetrapyrrole metabolic processGO:0033013110.020
regulation of anatomical structure sizeGO:00900661350.019
epithelium migrationGO:0090132190.019
negative regulation of cellular component organizationGO:0051129830.019
secretionGO:00469033070.019
nucleobase containing small molecule metabolic processGO:00550863160.019
response to biotic stimulusGO:00096072260.019
embryo developmentGO:0009790490.019
negative regulation of calcium ion transport into cytosolGO:001052340.019
positive regulation of nervous system developmentGO:00519621780.019
thyroid gland developmentGO:003087810.019
regulation of transcription from rna polymerase ii promoterGO:00063572340.019
positive regulation of protein phosphorylationGO:00019341350.018
apoptotic processGO:00069153810.018
single organism reproductive processGO:00447022970.018
positive regulation of cell developmentGO:00107201760.018
regulation of protein phosphorylationGO:00019321830.018
response to cytokineGO:00340972150.018
response to glucoseGO:00097491360.018
response to metal ionGO:00100382530.018
cellular amino acid metabolic processGO:00065201070.017
positive regulation of phosphorylationGO:00423271770.017
reproductive structure developmentGO:00486081280.017
positive regulation of camp metabolic processGO:0030816310.017
response to radiationGO:00093141370.017
positive regulation of protein modification processGO:00314011420.017
negative regulation of phosphate metabolic processGO:0045936800.017
protein maturationGO:0051604680.017
leukocyte proliferationGO:0070661290.017
organonitrogen compound catabolic processGO:19015651790.017
nucleotide biosynthetic processGO:0009165980.017
hormone transportGO:00099141210.017
keratan sulfate metabolic processGO:004233910.017
regulation of multicellular organismal developmentGO:20000263760.016
membrane organizationGO:0061024940.016
regulation of body fluid levelsGO:0050878900.016
regulation of nucleic acid templated transcriptionGO:19035063800.016
developmental process involved in reproductionGO:00030061590.016
positive regulation of camp biosynthetic processGO:0030819280.016
lymphocyte mediated immunityGO:0002449140.016
taxisGO:0042330670.016
regulation of smooth muscle cell proliferationGO:0048660750.016
receptor mediated endocytosisGO:0006898420.016
negative regulation of protein metabolic processGO:00512481140.016
cellular homeostasisGO:00197252520.016
regulation of angiotensin levels in bloodGO:000200220.016
protein localizationGO:00081041910.016
mapk cascadeGO:00001651400.016
reproductive system developmentGO:00614581280.015
regulation of cellular component organizationGO:00511283680.015
response to campGO:0051591910.015
reproductionGO:00000032450.015
defense responseGO:00069521940.015
negative regulation of natural killer cell mediated immunityGO:000271640.015
response to glucocorticoidGO:00513842230.015
cation transmembrane transportGO:00986552630.015
cell adhesionGO:00071551100.015
mitochondrial fusionGO:000805320.015
purine ribonucleotide metabolic processGO:00091502270.015
positive regulation of cellular amino acid metabolic processGO:004576410.014
regulation of hydrolase activityGO:00513361430.014
lymphocyte proliferationGO:0046651290.014
agingGO:00075682410.014
cellular protein localizationGO:00346131220.014
response to hypoxiaGO:00016662310.014
regulation of secretion by cellGO:19035302080.014
response to starvationGO:0042594590.014
cellular chemical homeostasisGO:00550822470.014
antigen processing and presentation of exogenous peptide antigen via mhc class iiGO:001988610.014
regulation of mapk cascadeGO:00434081160.014
multi organism reproductive processGO:00447032620.013
positive regulation of phosphate metabolic processGO:00459372620.013
positive regulation of programmed cell deathGO:00430681570.013
cellular response to insulin stimulusGO:0032869810.013
response to external biotic stimulusGO:00432072210.013
negative regulation of phosphorylationGO:0042326570.013
ion transmembrane transportGO:00342203650.013
positive regulation of cell deathGO:00109421840.013
cyclic nucleotide metabolic processGO:0009187800.013
negative regulation of secretionGO:0051048820.013
dna metabolic processGO:0006259960.013
regulation of nucleocytoplasmic transportGO:0046822280.013
cellular macromolecule localizationGO:00707271220.013
response to folic acidGO:0051593140.013
multicellular organismal catabolic processGO:004424320.013
tissue morphogenesisGO:0048729220.012
cell cell signalingGO:00072673350.012
ribonucleotide metabolic processGO:00092592310.012
carbohydrate derivative biosynthetic processGO:19011371240.012
tissue remodelingGO:0048771400.012
regulation of heart morphogenesisGO:200082620.012
regulation of blood coagulationGO:003019390.012
positive regulation of cellular biosynthetic processGO:00313282950.012
aromatic compound catabolic processGO:00194391680.012
triglyceride homeostasisGO:007032820.012
developmental growthGO:00485891000.012
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.012
smooth muscle cell proliferationGO:0048659770.012
response to oxygen levelsGO:00704822650.012
cellular response to corticosteroid stimulusGO:0071384690.012
negative regulation of release of sequestered calcium ion into cytosolGO:005128040.012
reactive nitrogen species metabolic processGO:200105710.012
intracellular signal transductionGO:00355563140.012
positive regulation of nitrogen compound metabolic processGO:00511733340.012
synaptic transmissionGO:00072682350.012
regulation of stress activated protein kinase signaling cascadeGO:0070302230.012
cation transportGO:00068123820.012
ribonucleotide biosynthetic processGO:0009260850.012
cell part morphogenesisGO:00329901230.011
response to molecule of bacterial originGO:00022371940.011
single organism carbohydrate metabolic processGO:00447231180.011
cellular response to starvationGO:0009267270.011
muscle structure developmentGO:0061061870.011
negative regulation of lipase activityGO:006019230.011
regulation of t cell proliferationGO:0042129170.011
branched chain amino acid transportGO:001580320.011
purine nucleotide biosynthetic processGO:0006164830.011
respiratory system developmentGO:0060541450.011
regulation of cell differentiationGO:00455953200.011
sensory perception of bitter tasteGO:005091340.011
multicellular organismal reproductive processGO:00486092330.011
positive regulation of cell differentiationGO:00455972170.011
positive regulation of cell proliferationGO:00082842490.011
cellular response to oxygen containing compoundGO:19017013860.011
proteolysis involved in cellular protein catabolic processGO:0051603190.011
regulation of jnk cascadeGO:0046328190.011
behaviorGO:00076102050.010
wound healingGO:00420601220.010
purine containing compound biosynthetic processGO:0072522850.010
purine ribonucleotide biosynthetic processGO:0009152810.010
negative regulation of immune system processGO:0002683390.010
negative regulation of calcium ion importGO:009028120.010
transmembrane transportGO:00550854120.010
response to ketoneGO:19016541820.010
regulation of ion transportGO:00432692450.010
innate immune responseGO:0045087350.010

Grn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.437
inherited metabolic disorderDOID:65500.437
disease of anatomical entityDOID:700.133
nervous system diseaseDOID:86300.133
lipid storage diseaseDOID:945500.065
lysosomal storage diseaseDOID:321100.065
central nervous system diseaseDOID:33100.026