Rattus norvegicus

0 known processes

Top1mt

topoisomerase (DNA) I, mitochondrial

Top1mt biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of multicellular organismal developmentGO:20000263760.043
carbohydrate derivative metabolic processGO:19011353460.043
single organism biosynthetic processGO:00447113420.042
rna biosynthetic processGO:00327743800.041
organic acid metabolic processGO:00060822920.039
response to inorganic substanceGO:00100353770.039
oxoacid metabolic processGO:00434362900.038
brain developmentGO:00074202470.036
regulation of cellular component organizationGO:00511283680.036
positive regulation of multicellular organismal processGO:00512403870.035
response to nutrient levelsGO:00316673700.033
cellular response to stressGO:00335542690.033
regulation of rna biosynthetic processGO:20011413810.033
programmed cell deathGO:00125013920.032
regulation of molecular functionGO:00650093980.032
organic substance catabolic processGO:19015753160.032
transcription dna templatedGO:00063513770.032
cellular amino acid metabolic processGO:00065201070.031
organonitrogen compound biosynthetic processGO:19015661670.031
central nervous system developmentGO:00074173110.031
nucleoside phosphate metabolic processGO:00067532830.029
negative regulation of macromolecule metabolic processGO:00106052600.028
cellular component biogenesisGO:00440853680.028
nucleotide metabolic processGO:00091172790.028
nucleobase containing small molecule metabolic processGO:00550863160.028
regulation of apoptotic processGO:00429813350.027
nucleic acid templated transcriptionGO:00976593790.027
response to extracellular stimulusGO:00099913800.027
protein complex subunit organizationGO:00718223020.027
regulation of protein metabolic processGO:00512462890.026
glycosyl compound metabolic processGO:19016571820.026
intracellular signal transductionGO:00355563140.026
head developmentGO:00603222470.026
catabolic processGO:00090563510.025
organophosphate metabolic processGO:00196373700.025
response to nutrientGO:00075842480.025
regulation of cell differentiationGO:00455953200.025
cellular component assemblyGO:00226073600.025
purine nucleotide metabolic processGO:00061632290.025
regulation of programmed cell deathGO:00430673410.025
purine containing compound metabolic processGO:00725212530.025
neuron differentiationGO:00301823680.025
purine nucleoside metabolic processGO:00422781690.024
reproductive processGO:00224143720.024
cellular ketone metabolic processGO:0042180510.024
multicellular organismal reproductive processGO:00486092330.024
regulation of cellular protein metabolic processGO:00322682670.024
cellular catabolic processGO:00442482950.024
apoptotic processGO:00069153810.024
positive regulation of phosphate metabolic processGO:00459372620.024
ribonucleotide metabolic processGO:00092592310.024
heterocycle catabolic processGO:00467001670.023
nucleobase containing compound catabolic processGO:00346551520.023
regulation of cell developmentGO:00602842630.023
regulation of nervous system developmentGO:00519602640.023
organelle organizationGO:00069962660.023
nucleoside metabolic processGO:00091161790.023
neuron projection developmentGO:00311752730.023
regulation of transcription dna templatedGO:00063553740.023
protein complex assemblyGO:00064612630.023
macromolecule localizationGO:00330362520.022
regulation of intracellular signal transductionGO:19025312180.022
regulation of neurogenesisGO:00507672470.022
macromolecular complex assemblyGO:00650032730.022
protein localizationGO:00081041910.022
positive regulation of molecular functionGO:00440932300.022
multicellular organism reproductionGO:00325042330.022
cellular response to organic cyclic compoundGO:00714072020.021
positive regulation of cellular biosynthetic processGO:00313282950.021
positive regulation of nitrogen compound metabolic processGO:00511733340.021
nitrogen compound transportGO:00717052290.021
regulation of nucleic acid templated transcriptionGO:19035063800.021
macromolecular complex subunit organizationGO:00439333390.021
purine ribonucleoside metabolic processGO:00461281680.021
amine metabolic processGO:0009308380.021
protein phosphorylationGO:00064683450.021
positive regulation of neurogenesisGO:00507691650.021
reproductionGO:00000032450.021
rna metabolic processGO:00160704060.021
regulation of membrane potentialGO:00423911100.020
positive regulation of developmental processGO:00510942830.020
cellular amine metabolic processGO:0044106380.020
regulation of signal transductionGO:00099663180.020
cation transportGO:00068123820.020
aromatic compound catabolic processGO:00194391680.020
positive regulation of phosphorus metabolic processGO:00105622620.020
cellular homeostasisGO:00197252520.020
cellular nitrogen compound catabolic processGO:00442701630.020
organic cyclic compound catabolic processGO:19013611750.019
positive regulation of cell differentiationGO:00455972170.019
positive regulation of biosynthetic processGO:00098913190.019
neurological system processGO:00508772190.019
regulation of anatomical structure morphogenesisGO:00226031410.019
positive regulation of cellular component organizationGO:00511302000.019
multi organism reproductive processGO:00447032620.019
single organism catabolic processGO:00447122830.019
cellular response to endogenous stimulusGO:00714953770.019
chemical homeostasisGO:00488782920.019
single organism reproductive processGO:00447022970.018
ribonucleoside metabolic processGO:00091191740.018
negative regulation of metabolic processGO:00098923310.018
ribose phosphate metabolic processGO:00196932350.018
purine ribonucleotide metabolic processGO:00091502270.018
regulation of canonical wnt signaling pathwayGO:006082840.018
regulation of cell projection organizationGO:00313441750.018
positive regulation of protein metabolic processGO:00512471780.018
regulation of phosphate metabolic processGO:00192203490.018
positive regulation of catalytic activityGO:00430851840.018
positive regulation of nucleobase containing compound metabolic processGO:00459353190.017
anatomical structure morphogenesisGO:00096532980.017
regulation of catalytic activityGO:00507903040.017
regulation of neuron differentiationGO:00456642080.017
carboxylic acid metabolic processGO:00197522890.017
response to oxygen levelsGO:00704822650.017
transmembrane transportGO:00550854120.017
response to carbohydrateGO:00097431830.017
positive regulation of cell developmentGO:00107201760.017
response to peptide hormoneGO:00434342780.017
cell projection organizationGO:00300303020.017
regulation of neuron projection developmentGO:00109751610.017
small gtpase mediated signal transductionGO:0007264360.016
regulation of phosphorus metabolic processGO:00511743490.016
regulation of cellular amino acid metabolic processGO:000652120.016
negative regulation of cell communicationGO:00106481580.016
negative regulation of cellular metabolic processGO:00313242810.016
positive regulation of cell deathGO:00109421840.016
regulation of cellular amine metabolic processGO:003323880.016
tissue developmentGO:00098882520.016
regulation of transcription from rna polymerase ii promoterGO:00063572340.016
positive regulation of rna metabolic processGO:00512542030.016
intracellular transportGO:00469071850.016
positive regulation of cell proliferationGO:00082842490.016
growthGO:00400071650.016
neuron developmentGO:00486662860.016
cellular response to hormone stimulusGO:00328702470.016
response to bacteriumGO:00096172000.016
transcription from rna polymerase ii promoterGO:00063662520.015
organonitrogen compound catabolic processGO:19015651790.015
response to monosaccharideGO:00342841590.015
proteolysisGO:00065081750.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
response to temperature stimulusGO:0009266940.015
ras protein signal transductionGO:0007265290.015
positive regulation of cellular amine metabolic processGO:003324030.015
positive regulation of response to stimulusGO:00485842850.015
single organism organelle organizationGO:19025891800.015
negative regulation of biosynthetic processGO:00098901680.015
purine ribonucleotide catabolic processGO:00091541360.015
coenzyme metabolic processGO:0006732860.015
developmental process involved in reproductionGO:00030061590.015
response to estrogenGO:00436272320.015
ion transmembrane transportGO:00342203650.015
protein complex biogenesisGO:00702712630.015
response to acid chemicalGO:00011012220.015
negative regulation of gene expressionGO:00106291990.014
metal ion transportGO:00300012890.014
regulation of cellular ketone metabolic processGO:0010565270.014
response to cytokineGO:00340972150.014
negative regulation of programmed cell deathGO:00430691830.014
response to estradiolGO:00323551640.014
response to hexoseGO:00097461440.014
developmental growthGO:00485891000.014
organophosphate catabolic processGO:00464341480.014
purine ribonucleoside triphosphate catabolic processGO:00092071220.014
purine nucleotide catabolic processGO:00061951360.014
synaptic transmissionGO:00072682350.014
regulation of cellular localizationGO:00603412630.014
cofactor metabolic processGO:0051186950.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
negative regulation of cellular biosynthetic processGO:00313271610.014
response to biotic stimulusGO:00096072260.014
negative regulation of apoptotic processGO:00430661810.014
homeostatic processGO:00425923310.014
negative regulation of signalingGO:00230571570.014
cellular response to oxygen containing compoundGO:19017013860.014
positive regulation of cellular protein metabolic processGO:00322701670.013
positive regulation of phosphorylationGO:00423271770.013
positive regulation of transportGO:00510502450.013
response to ketoneGO:19016541820.013
cytoplasmic transportGO:00164821150.013
response to growth factorGO:00708481890.013
regulation of phosphorylationGO:00423252480.013
nucleoside phosphate catabolic processGO:19012921400.013
monovalent inorganic cation transportGO:00156721720.013
carbohydrate derivative biosynthetic processGO:19011371240.013
negative regulation of cell deathGO:00605482290.013
reproductive structure developmentGO:00486081280.013
regulation of response to stressGO:00801341260.013
purine nucleoside triphosphate catabolic processGO:00091461220.013
ribonucleoside catabolic processGO:00424541260.013
cation homeostasisGO:00550801950.013
single organism cellular localizationGO:19025801020.013
regulation of growthGO:00400081050.013
negative regulation of response to stimulusGO:00485851550.013
ion homeostasisGO:00508012120.013
carbohydrate metabolic processGO:00059751300.013
secretionGO:00469033070.013
synaptic growth at neuromuscular junctionGO:005112410.013
adult locomotory behaviorGO:000834440.013
response to glucoseGO:00097491360.013
purine containing compound catabolic processGO:00725231380.012
response to metal ionGO:00100382530.012
immune system processGO:00023762040.012
cellular chemical homeostasisGO:00550822470.012
positive regulation of gene expressionGO:00106282440.012
response to external biotic stimulusGO:00432072210.012
nucleotide catabolic processGO:00091661390.012
carbohydrate derivative catabolic processGO:19011361470.012
regulation of catabolic processGO:00098941130.012
gamete generationGO:00072761240.012
nucleoside catabolic processGO:00091641260.012
sexual reproductionGO:00199531480.012
nucleoside triphosphate catabolic processGO:00091431230.012
single organism intracellular transportGO:19025821660.012
cation transmembrane transportGO:00986552630.012
cell growthGO:00160491040.012
amide transportGO:00428861050.012
eye morphogenesisGO:004859240.012
response to mechanical stimulusGO:00096121340.012
positive regulation of neuron differentiationGO:00456661260.012
spermatogenesisGO:0007283990.012
positive regulation of nervous system developmentGO:00519621780.012
negative regulation of multicellular organismal processGO:00512412030.012
positive regulation of macromolecule biosynthetic processGO:00105572470.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
response to decreased oxygen levelsGO:00362932370.012
forebrain developmentGO:0030900980.012
glycosyl compound catabolic processGO:19016581260.012
sex differentiationGO:00075481130.012
mitochondrial rna metabolic processGO:000095910.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
nucleotide biosynthetic processGO:0009165980.011
anion transportGO:00068201780.011
organophosphate biosynthetic processGO:00904071430.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
response to ethanolGO:00454711620.011
negative regulation of molecular functionGO:00440921330.011
response to hypoxiaGO:00016662310.011
response to other organismGO:00517072200.011
heart morphogenesisGO:000300730.011
response to radiationGO:00093141370.011
rhythmic processGO:00485111560.011
regulation of nucleotide metabolic processGO:00061401170.011
multicellular organismal signalingGO:0035637440.011
reactive oxygen species biosynthetic processGO:190340980.011
purine nucleoside catabolic processGO:00061521240.011
response to corticosteroidGO:00319602350.011
response to heatGO:0009408600.011
response to transition metal nanoparticleGO:19902671220.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
cellular macromolecule localizationGO:00707271220.011
protein oligomerizationGO:00512591910.011
response to vitaminGO:00332731310.011
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
response to oxidative stressGO:00069791860.011
guanosine containing compound metabolic processGO:1901068740.011
male gamete generationGO:0048232990.011
positive regulation of rna biosynthetic processGO:19026801970.011
cellular protein localizationGO:00346131220.011
nucleoside phosphate biosynthetic processGO:19012931020.011
ncrna processingGO:003447030.011
regulation of cell proliferationGO:00421273590.011
purine ribonucleoside catabolic processGO:00461301240.011
negative regulation of transportGO:00510511360.011
cell motilityGO:00488702020.011
establishment of protein localizationGO:00451841410.011
nucleoside triphosphate metabolic processGO:00091411440.011
positive regulation of cell projection organizationGO:00313461110.011
reproductive system developmentGO:00614581280.010
response to molecule of bacterial originGO:00022371940.010
cellular component movementGO:00069282480.010
action potentialGO:0001508540.010
metal ion homeostasisGO:00550651860.010
cell cell signalingGO:00072673350.010
protein transportGO:00150311320.010
vesicle mediated transportGO:00161921810.010
response to toxic substanceGO:00096361330.010
regulation of system processGO:00440572080.010
negative regulation of rna biosynthetic processGO:19026791180.010
cellular response to growth factor stimulusGO:00713631620.010
purine nucleoside triphosphate metabolic processGO:00091441410.010
hepaticobiliary system developmentGO:0061008900.010
response to purine containing compoundGO:00140741260.010
ribonucleotide biosynthetic processGO:0009260850.010
positive regulation of catabolic processGO:0009896780.010
positive regulation of cellular catabolic processGO:0031331710.010
positive regulation of programmed cell deathGO:00430681570.010
regulation of protein modification processGO:00313991940.010
positive regulation of protein modification processGO:00314011420.010
regulation of synaptic growth at neuromuscular junctionGO:000858210.010
cellular response to cytokine stimulusGO:00713451270.010
regulation of cellular component movementGO:00512701500.010
negative regulation of nucleobase containing compound metabolic processGO:00459341530.010
regulation of rna metabolic processGO:00512523910.010

Top1mt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.021
disease of anatomical entityDOID:700.021
sensory system diseaseDOID:005015500.015
disease of metabolismDOID:001466700.014
musculoskeletal system diseaseDOID:1700.012