Rattus norvegicus

0 known processes

Aph1a

anterior pharynx defective 1 homolog A (C. elegans)

(Aliases: RGD1311546)

Aph1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single organism intracellular transportGO:19025821660.300
response to mechanical stimulusGO:00096121340.191
macromolecule localizationGO:00330362520.170
regulation of cellular component organizationGO:00511283680.163
intracellular transportGO:00469071850.135
apoptotic processGO:00069153810.119
protein transportGO:00150311320.109
anatomical structure morphogenesisGO:00096532980.104
protein complex biogenesisGO:00702712630.103
negative regulation of cellular metabolic processGO:00313242810.102
response to hypoxiaGO:00016662310.096
transmembrane transportGO:00550854120.096
proteolysisGO:00065081750.092
protein complex assemblyGO:00064612630.089
response to insulinGO:00328681330.088
negative regulation of signalingGO:00230571570.088
response to extracellular stimulusGO:00099913800.086
negative regulation of metabolic processGO:00098923310.079
regulation of organelle organizationGO:0033043800.077
carboxylic acid metabolic processGO:00197522890.076
negative regulation of cellular component organizationGO:0051129830.073
protein phosphorylationGO:00064683450.072
response to decreased oxygen levelsGO:00362932370.071
anion transportGO:00068201780.069
carboxylic acid transportGO:00469421150.069
establishment of protein localizationGO:00451841410.069
cellular response to organonitrogen compoundGO:00714171970.068
negative regulation of gene expressionGO:00106291990.067
regulation of apoptotic processGO:00429813350.065
positive regulation of programmed cell deathGO:00430681570.065
cellular protein localizationGO:00346131220.064
regulation of programmed cell deathGO:00430673410.064
protein localizationGO:00081041910.063
cellular component biogenesisGO:00440853680.062
negative regulation of nervous system developmentGO:0051961790.059
cellular response to nitrogen compoundGO:19016992100.058
vesicle mediated transportGO:00161921810.057
cellular response to stressGO:00335542690.057
anion transmembrane transportGO:0098656770.056
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.055
cellular component assemblyGO:00226073600.055
regulation of cellular component movementGO:00512701500.054
single organism cellular localizationGO:19025801020.052
regulation of endocytosisGO:0030100420.052
purine nucleotide metabolic processGO:00061632290.051
programmed cell deathGO:00125013920.050
single organism membrane organizationGO:0044802740.050
regulation of neurogenesisGO:00507672470.049
protein complex subunit organizationGO:00718223020.049
cellular response to oxygen containing compoundGO:19017013860.047
purine ribonucleoside catabolic processGO:00461301240.047
intracellular protein transportGO:0006886790.046
cellular macromolecule localizationGO:00707271220.046
macromolecular complex assemblyGO:00650032730.046
organic acid metabolic processGO:00060822920.046
positive regulation of cellular component movementGO:00512721020.045
negative regulation of cell deathGO:00605482290.045
regulation of cell proliferationGO:00421273590.045
catabolic processGO:00090563510.044
rna metabolic processGO:00160704060.044
lipid metabolic processGO:00066292830.044
purine containing compound metabolic processGO:00725212530.043
organelle organizationGO:00069962660.043
cardiovascular system developmentGO:00723581340.043
oxoacid metabolic processGO:00434362900.042
intracellular signal transductionGO:00355563140.042
gtp catabolic processGO:0006184710.042
amino acid transportGO:0006865700.042
transcription from rna polymerase ii promoterGO:00063662520.041
establishment of tissue polarityGO:000716420.041
neuron projection developmentGO:00311752730.040
regulation of mitochondrion organizationGO:001082170.040
glycosyl compound metabolic processGO:19016571820.039
central nervous system developmentGO:00074173110.039
nucleoside phosphate metabolic processGO:00067532830.039
regulation of protein metabolic processGO:00512462890.038
organic acid transportGO:00158491160.038
regulation of phosphorus metabolic processGO:00511743490.037
cellular lipid metabolic processGO:00442552080.036
regulation of molecular functionGO:00650093980.036
synaptic transmissionGO:00072682350.036
response to inorganic substanceGO:00100353770.035
cell cell signalingGO:00072673350.035
organic cyclic compound catabolic processGO:19013611750.035
cellular amino acid metabolic processGO:00065201070.035
protein localization to organelleGO:0033365570.035
negative regulation of nitrogen compound metabolic processGO:00511721610.035
regulation of locomotionGO:00400121480.035
cellular response to peptideGO:19016531330.035
ion transmembrane transportGO:00342203650.034
negative regulation of response to stimulusGO:00485851550.034
mitochondrion organizationGO:0007005350.034
response to carbohydrateGO:00097431830.034
secretionGO:00469033070.034
negative regulation of macromolecule metabolic processGO:00106052600.034
cell motilityGO:00488702020.034
organic substance catabolic processGO:19015753160.034
response to estrogenGO:00436272320.033
regulation of multicellular organismal developmentGO:20000263760.033
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.033
regulation of cell differentiationGO:00455953200.033
positive regulation of signalingGO:00230562700.032
positive regulation of cell proliferationGO:00082842490.032
positive regulation of molecular functionGO:00440932300.032
protein targetingGO:0006605610.032
regulation of synaptic plasticityGO:0048167700.031
head developmentGO:00603222470.031
protein oligomerizationGO:00512591910.031
cellular response to peptide hormone stimulusGO:00713751200.031
response to oxygen levelsGO:00704822650.031
positive regulation of cellular component organizationGO:00511302000.031
metal ion transportGO:00300012890.031
organic anion transportGO:00157111320.030
heterocycle catabolic processGO:00467001670.030
organophosphate metabolic processGO:00196373700.030
nitrogen compound transportGO:00717052290.029
carbohydrate derivative catabolic processGO:19011361470.029
negative regulation of programmed cell deathGO:00430691830.029
organonitrogen compound catabolic processGO:19015651790.029
negative regulation of macromolecule biosynthetic processGO:00105581480.029
purine nucleoside metabolic processGO:00422781690.029
cytoskeleton organizationGO:00070101110.029
negative regulation of apoptotic processGO:00430661810.029
amine metabolic processGO:0009308380.029
negative regulation of biosynthetic processGO:00098901680.029
cellular nitrogen compound catabolic processGO:00442701630.029
cation transportGO:00068123820.028
nucleobase containing small molecule metabolic processGO:00550863160.028
response to nutrientGO:00075842480.028
single organism carbohydrate metabolic processGO:00447231180.028
response to oxidative stressGO:00069791860.028
regulation of protein complex assemblyGO:0043254330.028
positive regulation of biosynthetic processGO:00098913190.028
aromatic compound catabolic processGO:00194391680.028
macromolecular complex subunit organizationGO:00439333390.028
ribose phosphate metabolic processGO:00196932350.028
immune system processGO:00023762040.028
negative regulation of rna metabolic processGO:00512531230.027
regulation of cellular ketone metabolic processGO:0010565270.027
transcription dna templatedGO:00063513770.027
regulation of vesicle mediated transportGO:0060627810.027
regulation of phosphorylationGO:00423252480.027
protein localization to membraneGO:0072657360.027
chemical homeostasisGO:00488782920.027
regulation of synaptic transmissionGO:00508041410.027
cellular response to hormone stimulusGO:00328702470.027
positive regulation of developmental processGO:00510942830.026
circulatory system processGO:00030131830.026
negative regulation of cell communicationGO:00106481580.026
response to nutrient levelsGO:00316673700.026
cellular chemical homeostasisGO:00550822470.026
cellular response to endogenous stimulusGO:00714953770.026
establishment of protein localization to organelleGO:0072594440.025
smooth muscle cell proliferationGO:0048659770.025
cellular response to mechanical stimulusGO:0071260480.025
sex differentiationGO:00075481130.025
regulation of ion transportGO:00432692450.025
positive regulation of cellular biosynthetic processGO:00313282950.025
regulation of cellular amino acid metabolic processGO:000652120.025
single organism organelle organizationGO:19025891800.025
localization of cellGO:00516742020.025
agingGO:00075682410.025
cellular response to external stimulusGO:00714961180.025
cellular protein complex assemblyGO:0043623440.025
regulation of catalytic activityGO:00507903040.025
purine ribonucleoside metabolic processGO:00461281680.025
negative regulation of transcription dna templatedGO:00458921160.025
regulation of neuron differentiationGO:00456642080.025
cellular amine metabolic processGO:0044106380.024
regulation of cytoskeleton organizationGO:0051493490.024
positive regulation of gene expressionGO:00106282440.024
smooth muscle cell migrationGO:0014909360.024
endomembrane system organizationGO:0010256480.024
action potentialGO:0001508540.024
nucleic acid templated transcriptionGO:00976593790.024
cellular ketone metabolic processGO:0042180510.024
positive regulation of cell motilityGO:2000147970.023
positive regulation of cell deathGO:00109421840.023
ribonucleoside metabolic processGO:00091191740.023
negative regulation of cellular biosynthetic processGO:00313271610.023
angiogenesisGO:0001525530.023
regulation of protein phosphorylationGO:00019321830.023
cellular ion homeostasisGO:00068731840.023
response to metal ionGO:00100382530.023
cellular response to insulin stimulusGO:0032869810.022
positive regulation of mitochondrion organizationGO:001082240.022
negative regulation of nucleobase containing compound metabolic processGO:00459341530.022
positive regulation of nitrogen compound metabolic processGO:00511733340.022
regulation of membrane potentialGO:00423911100.022
negative regulation of multicellular organismal processGO:00512412030.022
protein polymerizationGO:0051258220.022
regulation of rna metabolic processGO:00512523910.022
cellular response to abiotic stimulusGO:0071214850.022
regulation of transcription from rna polymerase ii promoterGO:00063572340.022
purine nucleoside catabolic processGO:00061521240.021
golgi vesicle transportGO:0048193220.021
nucleoside phosphate catabolic processGO:19012921400.021
homeostatic processGO:00425923310.021
regulation of mapk cascadeGO:00434081160.021
cellular catabolic processGO:00442482950.021
muscle tissue developmentGO:0060537580.021
nucleotide metabolic processGO:00091172790.021
response to glucoseGO:00097491360.021
positive regulation of multicellular organismal processGO:00512403870.021
reproductionGO:00000032450.021
ion homeostasisGO:00508012120.021
blood circulationGO:00080151830.021
rna biosynthetic processGO:00327743800.021
positive regulation of cellular amine metabolic processGO:003324030.021
lipid modificationGO:0030258520.021
g protein coupled receptor signaling pathwayGO:00071862420.020
regulation of smooth muscle cell proliferationGO:0048660750.020
cellular cation homeostasisGO:00300031800.020
regulation of cell projection organizationGO:00313441750.020
response to ethanolGO:00454711620.020
response to lead ionGO:0010288330.020
negative regulation of phosphate metabolic processGO:0045936800.020
cation transmembrane transportGO:00986552630.020
membrane organizationGO:0061024940.020
regulation of nervous system developmentGO:00519602640.020
purine containing compound catabolic processGO:00725231380.020
lipid biosynthetic processGO:00086101280.020
positive regulation of apoptotic processGO:00430651540.019
blood vessel developmentGO:0001568690.019
response to hexoseGO:00097461440.019
organ morphogenesisGO:0009887750.019
positive regulation of smooth muscle cell proliferationGO:0048661510.019
cytoplasmic transportGO:00164821150.019
negative regulation of protein metabolic processGO:00512481140.019
regulation of cellular component biogenesisGO:0044087860.019
response to peptideGO:19016522920.019
blood vessel morphogenesisGO:0048514580.018
cellular homeostasisGO:00197252520.018
divalent metal ion transportGO:00708381320.018
cell adhesionGO:00071551100.018
actin filament based processGO:0030029860.018
axonogenesisGO:0007409710.018
regulation of cellular amine metabolic processGO:003323880.018
cellular calcium ion homeostasisGO:00068741600.018
oxidation reduction processGO:00551143040.018
response to growth factorGO:00708481890.018
cation homeostasisGO:00550801950.018
cellular component morphogenesisGO:00329891550.018
cell morphogenesisGO:00009021420.018
response to monosaccharideGO:00342841590.018
positive regulation of nervous system developmentGO:00519621780.018
response to peptide hormoneGO:00434342780.018
positive regulation of neurogenesisGO:00507691650.018
regulation of cellular protein metabolic processGO:00322682670.018
inorganic cation transmembrane transportGO:00986622020.018
purine nucleoside triphosphate metabolic processGO:00091441410.017
release of cytochrome c from mitochondriaGO:000183680.017
positive regulation of catalytic activityGO:00430851840.017
negative regulation of signal transductionGO:0009968830.017
negative regulation of molecular functionGO:00440921330.017
striated muscle tissue developmentGO:0014706580.017
positive regulation of neuron differentiationGO:00456661260.017
purine nucleotide catabolic processGO:00061951360.017
positive regulation of transportGO:00510502450.017
inorganic ion transmembrane transportGO:00986602290.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
cellular metal ion homeostasisGO:00068751720.017
single organism catabolic processGO:00447122830.017
tube developmentGO:0035295890.017
nucleoside metabolic processGO:00091161790.017
response to reactive oxygen speciesGO:00003021200.017
negative regulation of transportGO:00510511360.016
positive regulation of intracellular signal transductionGO:19025331380.016
cell cycle checkpointGO:000007520.016
response to other organismGO:00517072200.016
response to acid chemicalGO:00011012220.016
cellular macromolecular complex assemblyGO:0034622580.016
negative regulation of rna biosynthetic processGO:19026791180.016
regulation of intracellular signal transductionGO:19025312180.016
nucleobase containing compound catabolic processGO:00346551520.016
regulation of metal ion transportGO:00109591180.016
organophosphate catabolic processGO:00464341480.016
regulation of long term neuronal synaptic plasticityGO:0048169150.016
glycosyl compound catabolic processGO:19016581260.016
tissue remodelingGO:0048771400.016
lipid localizationGO:0010876620.016
regulation of system processGO:00440572080.016
rhythmic processGO:00485111560.016
regulation of proteasomal protein catabolic processGO:006113640.015
protein processingGO:0016485680.015
regulation of neuron projection developmentGO:00109751610.015
response to estradiolGO:00323551640.015
positive regulation of ion transportGO:0043270940.015
negative regulation of developmental processGO:00510931250.015
ribonucleoside triphosphate metabolic processGO:00091991410.015
ribonucleoside triphosphate catabolic processGO:00092031220.015
response to heatGO:0009408600.015
endocytosisGO:0006897840.015
single organismal cell cell adhesionGO:0016337420.015
cellular response to growth factor stimulusGO:00713631620.015
insulin like growth factor receptor signaling pathwayGO:004800930.015
amino acid transmembrane transportGO:0003333330.015
reproductive processGO:00224143720.014
neuron differentiationGO:00301823680.014
ribonucleotide metabolic processGO:00092592310.014
glycerolipid metabolic processGO:0046486670.014
cell projection morphogenesisGO:00488581230.014
single organism biosynthetic processGO:00447113420.014
regulation of anatomical structure sizeGO:00900661350.014
muscle tissue morphogenesisGO:006041510.014
biological adhesionGO:00226101100.014
muscle organ morphogenesisGO:004864410.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
positive regulation of organelle organizationGO:0010638480.014
purine ribonucleotide metabolic processGO:00091502270.014
positive regulation of cell developmentGO:00107201760.014
multicellular organismal reproductive processGO:00486092330.014
regulation of cell migrationGO:00303341280.014
regulation of homeostatic processGO:00328441010.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.014
retina morphogenesis in camera type eyeGO:006004210.014
positive regulation of locomotionGO:00400171020.014
regulation of transcription dna templatedGO:00063553740.014
embryo developmentGO:0009790490.014
regulation of cellular localizationGO:00603412630.014
protein heterooligomerizationGO:0051291890.014
response to bacteriumGO:00096172000.014
regulation of phosphate metabolic processGO:00192203490.014
mapk cascadeGO:00001651400.014
brain developmentGO:00074202470.014
heart morphogenesisGO:000300730.013
neuron developmentGO:00486662860.013
response to radiationGO:00093141370.013
muscle cell proliferationGO:0033002840.013
regulation of smooth muscle cell migrationGO:0014910360.013
regulation of reactive oxygen species metabolic processGO:2000377260.013
regulation of rna biosynthetic processGO:20011413810.013
regulation of anatomical structure morphogenesisGO:00226031410.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
feeding behaviorGO:0007631530.013
positive regulation of rna metabolic processGO:00512542030.013
asymmetric protein localizationGO:000810520.013
monocarboxylic acid metabolic processGO:00327871520.013
cell junction organizationGO:0034330210.013
calcium ion homeostasisGO:00550741620.013
reproductive system developmentGO:00614581280.013
regulation of actin cytoskeleton organizationGO:0032956300.013
positive regulation of cellular protein metabolic processGO:00322701670.013
multicellular organismal signalingGO:0035637440.013
regulation of kinase activityGO:00435491170.013
regulation of muscle system processGO:0090257790.013
negative regulation of phosphorus metabolic processGO:0010563800.013
regulation of protein localizationGO:0032880810.013
protein maturationGO:0051604680.013
regulation of fat cell differentiationGO:004559830.013
ribonucleoside catabolic processGO:00424541260.012
single organism reproductive processGO:00447022970.012
positive regulation of mapk cascadeGO:0043410920.012
carbohydrate metabolic processGO:00059751300.012
digestive tract developmentGO:0048565390.012
negative regulation of cell differentiationGO:0045596990.012
response to corticosteroidGO:00319602350.012
response to ketoneGO:19016541820.012
actin cytoskeleton organizationGO:0030036730.012
small gtpase mediated signal transductionGO:0007264360.012
establishment of planar polarityGO:000173610.012
transmission of nerve impulseGO:0019226420.012
signal releaseGO:00230611450.012
circulatory system developmentGO:00723591340.012
heart processGO:0003015570.012
cellular response to hypoxiaGO:0071456510.012
nucleoside catabolic processGO:00091641260.012
response to molecule of bacterial originGO:00022371940.012
neurological system processGO:00508772190.012
positive regulation of phosphorylationGO:00423271770.012
muscle organ developmentGO:0007517500.012
organophosphate biosynthetic processGO:00904071430.012
response to vitaminGO:00332731310.012
regulation of cellular component sizeGO:0032535510.012
purine nucleoside triphosphate catabolic processGO:00091461220.012
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.012
eye morphogenesisGO:004859240.012
regulation of establishment of protein localizationGO:0070201690.012
development of primary sexual characteristicsGO:00451371070.012
negative regulation of neurogenesisGO:0050768780.012
behaviorGO:00076102050.012
response to ammonium ionGO:0060359710.012
calcium ion transportGO:00068161310.012
regulation of plasma lipoprotein particle levelsGO:009700630.011
cellular response to unfolded proteinGO:003462020.011
response to glucocorticoidGO:00513842230.011
single organism behaviorGO:00447081300.011
positive regulation of nucleobase containing compound metabolic processGO:00459353190.011
branched chain amino acid transportGO:001580320.011
cellular response to topologically incorrect proteinGO:003596730.011
regulation of tube sizeGO:0035150890.011
regulation of growthGO:00400081050.011
secretion by cellGO:00329402480.011
monosaccharide metabolic processGO:0005996610.011
regulation of platelet derived growth factor receptor signaling pathwayGO:001064020.011
negative regulation of cellular protein metabolic processGO:00322691060.011
morphogenesis of a polarized epitheliumGO:000173810.011
regulation of proteolysisGO:0030162660.011
monocarboxylic acid transportGO:0015718520.011
single organism cell adhesionGO:0098602460.011
response to activityGO:0014823730.011
muscle system processGO:00030121150.011
positive regulation of phosphorus metabolic processGO:00105622620.011
female sex differentiationGO:0046660590.011
male gamete generationGO:0048232990.011
cell projection organizationGO:00300303020.011
antigen processing and presentationGO:001988220.011
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000333920.011
cellular component movementGO:00069282480.011
ribonucleotide catabolic processGO:00092611360.011
tissue developmentGO:00098882520.011
fatty acid metabolic processGO:0006631990.011
amide transportGO:00428861050.011
establishment of protein localization to membraneGO:0090150160.011
positive regulation of cell differentiationGO:00455972170.011
regulation of cell growthGO:0001558850.011
hormone transportGO:00099141210.011
camera type eye morphogenesisGO:004859320.011
cellular response to oxidative stressGO:0034599760.011
regulation of protein modification processGO:00313991940.011
regulation of protein polymerizationGO:0032271190.010
axis specificationGO:000979840.010
plasma lipoprotein particle clearanceGO:003438130.010
multi organism reproductive processGO:00447032620.010
response to alkaloidGO:00432791320.010
regulation of cell developmentGO:00602842630.010
regulation of hormone levelsGO:00108171870.010
phospholipid metabolic processGO:0006644610.010
cardiac conductionGO:006133720.010
regulation of actin filament based processGO:0032970420.010
cytosolic calcium ion homeostasisGO:00514801400.010
cellular response to oxygen levelsGO:0071453600.010
negative regulation of protein import into nucleus translocationGO:003315910.010
multicellular organism reproductionGO:00325042330.010
fc receptor mediated stimulatory signaling pathwayGO:000243130.010

Aph1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
nervous system diseaseDOID:86300.024
primary immunodeficiency diseaseDOID:61200.020
immune system diseaseDOID:291400.020
cardiovascular system diseaseDOID:128700.015
musculoskeletal system diseaseDOID:1700.014
muscular diseaseDOID:008000000.013
muscle tissue diseaseDOID:6600.013
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
gastrointestinal system cancerDOID:311900.012
large intestine cancerDOID:567200.011
intestinal cancerDOID:1015500.011
colon cancerDOID:21900.011
colorectal cancerDOID:925600.011
colon carcinomaDOID:152000.011
disease of metabolismDOID:001466700.011
heart diseaseDOID:11400.011
central nervous system diseaseDOID:33100.010