Rattus norvegicus

103 known processes

Pax4

paired box 4

Pax4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neurological system processGO:00508772190.389
cellular response to endogenous stimulusGO:00714953770.303
Rat
anion transportGO:00068201780.237
cellular response to lipidGO:00713962010.208
Rat
transmembrane transportGO:00550854120.193
response to purine containing compoundGO:00140741260.186
eye developmentGO:0001654500.164
ion transmembrane transportGO:00342203650.160
anterior posterior pattern specificationGO:000995210.154
camera type eye developmentGO:0043010480.143
rna metabolic processGO:00160704060.139
tissue developmentGO:00098882520.131
calcium ion importGO:0070509220.129
cell cell signalingGO:00072673350.124
Rat
positive regulation of cellular biosynthetic processGO:00313282950.114
regulation of rna metabolic processGO:00512523910.114
positive regulation of biosynthetic processGO:00098913190.110
organic anion transportGO:00157111320.104
multi multicellular organism processGO:00447061380.103
phototransduction visible lightGO:000760320.101
cellular response to steroid hormone stimulusGO:0071383930.098
nitrogen compound transportGO:00717052290.091
Rat
negative regulation of multicellular organismal processGO:00512412030.090
positive regulation of nitrogen compound metabolic processGO:00511733340.087
synaptic transmission gabaergicGO:0051932220.086
carboxylic acid transportGO:00469421150.085
positive regulation of catalytic activityGO:00430851840.083
negative regulation of signalingGO:00230571570.080
response to peptideGO:19016522920.080
Rat
hepaticobiliary system developmentGO:0061008900.078
response to estradiolGO:00323551640.076
cellular response to alcoholGO:0097306870.076
negative regulation of cell communicationGO:00106481580.076
apoptotic processGO:00069153810.074
head developmentGO:00603222470.074
Rat
regulation of cell differentiationGO:00455953200.073
Mouse Rat
response to radiationGO:00093141370.073
gland developmentGO:00487321550.072
cellular response to oxygen containing compoundGO:19017013860.071
Rat
programmed cell deathGO:00125013920.070
response to peptide hormoneGO:00434342780.069
Rat
regulation of cell proliferationGO:00421273590.069
central nervous system developmentGO:00074173110.067
Rat
lens development in camera type eyeGO:0002088130.066
positive regulation of transcription dna templatedGO:00458931970.065
response to dexamethasoneGO:0071548490.064
tonic smooth muscle contractionGO:001482040.064
organ morphogenesisGO:0009887750.063
cellular ketone metabolic processGO:0042180510.060
macromolecular complex subunit organizationGO:00439333390.059
amino acid transportGO:0006865700.059
multicellular organismal reproductive processGO:00486092330.058
single organism reproductive processGO:00447022970.056
positive regulation of nucleobase containing compound metabolic processGO:00459353190.055
negative regulation of metabolic processGO:00098923310.055
neuron neuron synaptic transmissionGO:0007270600.053
positive regulation of rna metabolic processGO:00512542030.053
reproductive processGO:00224143720.052
intracellular signal transductionGO:00355563140.052
cation transportGO:00068123820.051
learning or memoryGO:0007611900.051
digestive system developmentGO:0055123410.050
positive regulation of gene expressionGO:00106282440.050
Rat
positive regulation of cellular component organizationGO:00511302000.050
response to campGO:0051591910.050
cellular response to abiotic stimulusGO:0071214850.049
response to woundingGO:00096112540.049
cellular response to organonitrogen compoundGO:00714171970.048
Rat
digestive tract developmentGO:0048565390.048
liver developmentGO:0001889900.048
response to corticosteroidGO:00319602350.047
response to ammonium ionGO:0060359710.047
regulation of transcription dna templatedGO:00063553740.047
heart morphogenesisGO:000300730.046
tube developmentGO:0035295890.046
regulation of molecular functionGO:00650093980.045
organic hydroxy compound transportGO:0015850770.043
homeostatic processGO:00425923310.043
Rat
positive regulation of cellular protein metabolic processGO:00322701670.042
regulation of intracellular signal transductionGO:19025312180.041
cellular response to stressGO:00335542690.040
retina development in camera type eyeGO:0060041270.040
purine nucleotide biosynthetic processGO:0006164830.040
response to organophosphorusGO:00466831020.040
cellular response to organic cyclic compoundGO:00714072020.040
circulatory system developmentGO:00723591340.039
cyclic nucleotide metabolic processGO:0009187800.039
multi organism reproductive processGO:00447032620.039
cation transmembrane transportGO:00986552630.039
secretionGO:00469033070.039
Rat
ovulation cycle processGO:0022602500.038
transcription from rna polymerase ii promoterGO:00063662520.038
Mouse Rat
protein complex subunit organizationGO:00718223020.038
regulation of rna biosynthetic processGO:20011413810.038
development of primary sexual characteristicsGO:00451371070.037
regulation of ion transportGO:00432692450.037
anatomical structure morphogenesisGO:00096532980.037
Rat
urinary bladder smooth muscle contractionGO:001483240.036
positive regulation of nucleic acid templated transcriptionGO:19035081970.036
protein complex biogenesisGO:00702712630.036
regenerationGO:00310991630.036
regulation of vesicle mediated transportGO:0060627810.035
cellular component morphogenesisGO:00329891550.035
cell projection organizationGO:00300303020.035
Rat
cellular chemical homeostasisGO:00550822470.034
Rat
detection of visible lightGO:000958430.034
response to estrogenGO:00436272320.034
positive regulation of rna biosynthetic processGO:19026801970.034
vesicle mediated transportGO:00161921810.033
transmission of nerve impulseGO:0019226420.033
cellular response to corticosteroid stimulusGO:0071384690.033
protein phosphorylationGO:00064683450.033
negative regulation of nucleic acid templated transcriptionGO:19035071170.033
negative regulation of cell proliferationGO:00082851190.033
positive regulation of protein phosphorylationGO:00019341350.033
protein complex assemblyGO:00064612630.032
epithelial cell migrationGO:0010631190.032
negative regulation of gene expressionGO:00106291990.032
negative regulation of macromolecule metabolic processGO:00106052600.032
regulation of cellular ketone metabolic processGO:0010565270.032
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.031
amide transportGO:00428861050.031
Rat
agingGO:00075682410.031
nucleotide biosynthetic processGO:0009165980.031
cell cycleGO:00070491010.031
circadian rhythmGO:0007623880.030
dicarboxylic acid transportGO:0006835340.030
cardiocyte differentiationGO:0035051220.030
cellular response to hormone stimulusGO:00328702470.029
Rat
negative regulation of nucleobase containing compound metabolic processGO:00459341530.029
negative regulation of response to stimulusGO:00485851550.029
regulation of neuron deathGO:19012141150.029
female pregnancyGO:00075651220.029
choline transportGO:001587140.029
negative regulation of rna biosynthetic processGO:19026791180.029
regulation of anion transportGO:0044070430.029
organic cyclic compound catabolic processGO:19013611750.029
brain developmentGO:00074202470.028
Rat
muscle cell proliferationGO:0033002840.028
lateral ventricle developmentGO:002167010.028
axis specificationGO:000979840.027
multicellular organism reproductionGO:00325042330.027
neuron developmentGO:00486662860.027
Rat
heart developmentGO:0007507720.027
regulation of multicellular organismal developmentGO:20000263760.027
Rat
sensory perceptionGO:00076001010.027
response to growth factorGO:00708481890.027
Rat
protein oligomerizationGO:00512591910.027
organic acid metabolic processGO:00060822920.027
positive regulation of long term synaptic potentiationGO:190027340.027
positive regulation of protein metabolic processGO:00512471780.026
rhythmic processGO:00485111560.026
negative regulation of rna metabolic processGO:00512531230.026
cellular component assemblyGO:00226073600.026
positive regulation of intracellular signal transductionGO:19025331380.026
cellular homeostasisGO:00197252520.026
Rat
cell activationGO:0001775970.026
cellular amine metabolic processGO:0044106380.026
growthGO:00400071650.025
regulation of nucleic acid templated transcriptionGO:19035063800.025
cell proliferation in external granule layerGO:002192410.025
ovulation cycleGO:0042698670.025
enzyme linked receptor protein signaling pathwayGO:00071671160.025
hyperosmotic responseGO:0006972180.025
response to glucocorticoidGO:00513842230.024
negative regulation of macromolecule biosynthetic processGO:00105581480.024
single organism biosynthetic processGO:00447113420.024
amine metabolic processGO:0009308380.024
regulation of catalytic activityGO:00507903040.024
regulation of transcription from rna polymerase ii promoterGO:00063572340.024
Mouse
rna biosynthetic processGO:00327743800.024
response to nutrient levelsGO:00316673700.023
positive regulation of macromolecule biosynthetic processGO:00105572470.023
neuron projection developmentGO:00311752730.023
Rat
cerebellar granule cell precursor proliferationGO:002193010.023
response to cocaineGO:0042220390.023
eye morphogenesisGO:004859240.023
metal ion homeostasisGO:00550651860.023
response to cgmpGO:007030530.023
regulation of cell projection organizationGO:00313441750.023
Rat
positive regulation of developmental processGO:00510942830.022
Mouse Rat
catabolic processGO:00090563510.022
regulation of apoptotic processGO:00429813350.022
positive regulation of cell differentiationGO:00455972170.022
Mouse Rat
cellular response to glucocorticoid stimulusGO:0071385680.022
regulation of protein kinase activityGO:00458591050.022
anion transmembrane transportGO:0098656770.022
forebrain developmentGO:0030900980.022
Rat
nucleic acid templated transcriptionGO:00976593790.021
regulation of cellular amino acid metabolic processGO:000652120.021
regulation of cell developmentGO:00602842630.021
Rat
reproductionGO:00000032450.021
retina morphogenesis in camera type eyeGO:006004210.021
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.021
regulation of cellular amine metabolic processGO:003323880.021
synaptic transmissionGO:00072682350.021
positive regulation of cell deathGO:00109421840.021
negative regulation of signal transductionGO:0009968830.021
regulation of saliva secretionGO:004687730.020
positive regulation of programmed cell deathGO:00430681570.020
monocarboxylic acid transportGO:0015718520.020
nucleoside phosphate metabolic processGO:00067532830.020
mesonephric tubule developmentGO:0072164140.020
organic acid transportGO:00158491160.020
multicellular organismal signalingGO:0035637440.020
regulation of secretionGO:00510462240.020
Rat
smooth muscle cell proliferationGO:0048659770.019
urinary tract smooth muscle contractionGO:001484840.019
negative regulation of nervous system developmentGO:0051961790.019
macromolecular complex assemblyGO:00650032730.019
regulation of ossificationGO:0030278320.019
regulation of signal transductionGO:00099663180.019
cell morphogenesis involved in differentiationGO:00009041190.019
positive regulation of saliva secretionGO:004687830.019
purine nucleotide catabolic processGO:00061951360.019
actin filament depolymerizationGO:003004230.018
response to other organismGO:00517072200.018
positive regulation of phosphorus metabolic processGO:00105622620.018
negative regulation of nitrogen compound metabolic processGO:00511721610.018
positive regulation of molecular functionGO:00440932300.018
negative regulation of synaptic transmission dopaminergicGO:003222740.018
acid secretionGO:0046717480.018
negative regulation of cellular metabolic processGO:00313242810.018
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.018
Mouse
blood vessel developmentGO:0001568690.018
cellular amino acid metabolic processGO:00065201070.018
oxoacid metabolic processGO:00434362900.018
cardiovascular system developmentGO:00723581340.018
detection of external stimulusGO:0009581130.018
negative regulation of transportGO:00510511360.017
transcription dna templatedGO:00063513770.017
divalent metal ion transportGO:00708381320.017
positive regulation of transportGO:00510502450.017
Rat
organonitrogen compound catabolic processGO:19015651790.017
regulation of organelle organizationGO:0033043800.017
single fertilizationGO:000733830.017
lipid transportGO:0006869610.017
ensheathment of neuronsGO:0007272400.017
organophosphate biosynthetic processGO:00904071430.017
response to osmotic stressGO:0006970420.017
reproductive structure developmentGO:00486081280.017
positive regulation of ion transportGO:0043270940.017
chemical homeostasisGO:00488782920.017
Rat
regulation of protein metabolic processGO:00512462890.017
excretionGO:0007588240.016
regulation of response to woundingGO:1903034690.016
developmental process involved in reproductionGO:00030061590.016
nucleoside phosphate biosynthetic processGO:19012931020.016
response to glucoseGO:00097491360.016
Rat
negative regulation of neuron differentiationGO:0045665620.016
regulation of hydrolase activityGO:00513361430.016
cardiac chamber developmentGO:000320510.016
embryonic skeletal system morphogenesisGO:004870430.016
regulation of cell growthGO:0001558850.016
muscle cell differentiationGO:0042692520.016
regulation of phosphorus metabolic processGO:00511743490.016
cellular divalent inorganic cation homeostasisGO:00725031620.016
carbohydrate derivative metabolic processGO:19011353460.016
sensory perception of light stimulusGO:005095330.016
positive regulation of response to stimulusGO:00485842850.016
heterocycle catabolic processGO:00467001670.016
regulation of cytoskeleton organizationGO:0051493490.016
regulation of behaviorGO:0050795610.016
regulation of phosphorylationGO:00423252480.016
regulation of smooth muscle cell proliferationGO:0048660750.016
organelle organizationGO:00069962660.016
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.016
bile acid and bile salt transportGO:0015721120.015
regulation of cellular protein metabolic processGO:00322682670.015
cellular glucan metabolic processGO:0006073230.015
positive regulation of cellular amine metabolic processGO:003324030.015
g protein coupled receptor internalizationGO:000203130.015
action potentialGO:0001508540.015
regulation of phosphate metabolic processGO:00192203490.015
neurotransmitter uptakeGO:000150430.015
embryonic pattern specificationGO:000988010.015
negative regulation of cellular biosynthetic processGO:00313271610.015
negative regulation of developmental processGO:00510931250.015
purine ribonucleotide biosynthetic processGO:0009152810.015
gastrulationGO:000736920.015
positive regulation of cellular component biogenesisGO:0044089550.015
proteolysisGO:00065081750.015
response to lipopolysaccharideGO:00324961910.015
regulation of canonical wnt signaling pathwayGO:006082840.015
response to extracellular stimulusGO:00099913800.015
positive regulation of the force of heart contraction by norepinephrineGO:000306110.015
organophosphate metabolic processGO:00196373700.015
response to retinoic acidGO:0032526630.015
muscle system processGO:00030121150.015
purine containing compound biosynthetic processGO:0072522850.014
regulation of kinase activityGO:00435491170.014
metal ion transportGO:00300012890.014
cellular response to acid chemicalGO:0071229750.014
Rat
wound healingGO:00420601220.014
regulation of organ formationGO:000315620.014
renal sodium excretionGO:0035812200.014
lipid localizationGO:0010876620.014
ribonucleotide catabolic processGO:00092611360.014
regulation of growthGO:00400081050.014
response to nutrientGO:00075842480.014
cgmp biosynthetic processGO:0006182150.014
response to nicotineGO:0035094510.014
lipid biosynthetic processGO:00086101280.014
embryonic skeletal system developmentGO:004870630.014
positive regulation of phosphorylationGO:00423271770.014
neuromuscular processGO:005090520.014
regulation of response to stressGO:00801341260.014
single organism organelle organizationGO:19025891800.014
neuronal action potentialGO:0019228350.013
regulation of calcium ion transportGO:0051924770.013
camera type eye morphogenesisGO:004859320.013
mapk cascadeGO:00001651400.013
positive regulation of apoptotic processGO:00430651540.013
organophosphate catabolic processGO:00464341480.013
ribonucleoside triphosphate catabolic processGO:00092031220.013
cellular nitrogen compound catabolic processGO:00442701630.013
sensory organ developmentGO:0007423740.013
digestive system processGO:0022600240.013
kidney epithelium developmentGO:0072073190.013
response to calcium ionGO:0051592590.013
cytosolic calcium ion homeostasisGO:00514801400.013
positive regulation of nervous system developmentGO:00519621780.013
Rat
positive regulation of the force of heart contraction by epinephrineGO:000305910.013
cellular response to dexamethasone stimulusGO:0071549360.013
cellular response to external stimulusGO:00714961180.013
protein homooligomerizationGO:0051260910.013
regulation of neuron differentiationGO:00456642080.013
Rat
regulation of protein serine threonine kinase activityGO:0071900640.013
positive regulation of protein modification processGO:00314011420.013
skeletal muscle tissue developmentGO:0007519310.013
female gonad developmentGO:0008585530.013
modified amino acid transportGO:0072337120.013
metanephric part of ureteric bud developmentGO:003550210.013
regulation of the force of heart contraction by chemical signalGO:000305720.013
response to external biotic stimulusGO:00432072210.013
cellular component biogenesisGO:00440853680.013
anatomical structure formation involved in morphogenesisGO:0048646830.013
microvillus assemblyGO:003003320.013
purine nucleotide metabolic processGO:00061632290.012
cellular response to nitrogen compoundGO:19016992100.012
Rat
monoamine transportGO:0015844430.012
saliva secretionGO:004654130.012
negative regulation of cell adhesion molecule productionGO:006035410.012
detection of abiotic stimulusGO:0009582130.012
energy reserve metabolic processGO:0006112250.012
positive regulation of transferase activityGO:0051347810.012
behaviorGO:00076102050.012
response to inorganic substanceGO:00100353770.012
negative regulation of uterine smooth muscle contractionGO:007047320.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
response to alkaloidGO:00432791320.012
cellular response to growth factor stimulusGO:00713631620.012
Rat
epithelium developmentGO:0060429960.012
Rat
negative regulation of synaptic transmissionGO:0050805290.012
embryonic axis specificationGO:000057810.012
immune effector processGO:0002252530.012
positive regulation of cell projection organizationGO:00313461110.012
regulation of metal ion transportGO:00109591180.012
regulation of fat cell differentiationGO:004559830.012
cellular response to glucose stimulusGO:0071333650.012
Rat
positive regulation of cell proliferationGO:00082842490.012
inorganic anion transportGO:0015698410.012
cytoskeleton organizationGO:00070101110.012
cyclic nucleotide biosynthetic processGO:0009190630.012
neuron differentiationGO:00301823680.012
Rat
organic hydroxy compound metabolic processGO:19016151150.011
neuron deathGO:00709971270.011
macromolecule catabolic processGO:0009057580.011
cell fate determinationGO:000170920.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
regulation of response to external stimulusGO:00321011060.011
response to toxic substanceGO:00096361330.011
regulation of anatomical structure morphogenesisGO:00226031410.011
striated muscle tissue developmentGO:0014706580.011
male gamete generationGO:0048232990.011
cellular metal ion homeostasisGO:00068751720.011
organic substance catabolic processGO:19015753160.011
positive regulation of mapk cascadeGO:0043410920.011
positive regulation of blood pressure by epinephrine norepinephrineGO:000332120.011
catecholamine transportGO:0051937370.011
response to acid chemicalGO:00011012220.011
Rat
regulation of cellular component organizationGO:00511283680.011
Rat
developmental growthGO:00485891000.011
phospholipase c activating serotonin receptor signaling pathwayGO:000720820.011
regulation of transmembrane transportGO:00347621220.011
negative regulation of cell developmentGO:0010721820.011
regulation of amino acid transportGO:0051955250.011
regulation of cell cycleGO:0051726730.011
calcium ion transportGO:00068161310.011
rho protein signal transductionGO:0007266110.011
negative regulation of molecular functionGO:00440921330.011
circulatory system processGO:00030131830.011
regulation of amine transportGO:0051952540.011
platelet aggregationGO:007052740.011
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.011
glandular epithelial cell differentiationGO:000206740.011
Rat
response to hexoseGO:00097461440.010
Rat
negative regulation of response to external stimulusGO:0032102370.010
detection of temperature stimulus involved in sensory perception of painGO:005096540.010
molting cycleGO:004230330.010
photoperiodismGO:000964840.010
negative regulation of cell differentiationGO:0045596990.010
cellular catabolic processGO:00442482950.010
steroid metabolic processGO:0008202730.010
nucleobase containing compound catabolic processGO:00346551520.010
phototransductionGO:000760230.010
memoryGO:0007613540.010
mesonephric epithelium developmentGO:0072163140.010
sex differentiationGO:00075481130.010
telencephalon developmentGO:0021537620.010
Rat
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.010
cell morphogenesisGO:00009021420.010
embryo developmentGO:0009790490.010
ossificationGO:0001503700.010
purine ribonucleotide catabolic processGO:00091541360.010
divalent inorganic cation homeostasisGO:00725071650.010
epithelial cell proliferationGO:0050673540.010

Pax4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.722
nervous system diseaseDOID:86300.722
eye and adnexa diseaseDOID:149200.722
sensory system diseaseDOID:005015500.722
eye diseaseDOID:561400.722
retinal diseaseDOID:567900.722
night blindnessDOID:849900.722
retinitis pigmentosaDOID:1058400.104
retinal degenerationDOID:846600.104
musculoskeletal system diseaseDOID:1700.026
connective tissue diseaseDOID:6500.026
disease of metabolismDOID:001466700.012
Human
central nervous system diseaseDOID:33100.011
kidney diseaseDOID:55700.010
urinary system diseaseDOID:1800.010