IMP: Integrative Multi-species Prediction

Rattus norvegicus

34 known processes

Cib1

calcium and integrin binding 1 (calmyrin)

(Aliases: Cib,Sip2-28)

Entrez: 81823
RGD: 620133
Ensembl: ENSRNOG00000033498
UniProtKB: Q9R010

Process Predictions
Disease Predictions

Cib1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
single organism catabolic process	GO:0044712	283	0.171
immune system process	GO:0002376	204	0.125	Mouse
catabolic process	GO:0009056	351	0.098
intracellular transport	GO:0046907	185	0.094	Human
cellular component assembly	GO:0022607	360	0.078
organophosphate metabolic process	GO:0019637	370	0.078
organic substance catabolic process	GO:1901575	316	0.071
macromolecular complex subunit organization	GO:0043933	339	0.060	Human
protein complex subunit organization	GO:0071822	302	0.060	Human
carbohydrate derivative catabolic process	GO:1901136	147	0.058
peptide biosynthetic process	GO:0043043	3	0.053
response to amino acid	GO:0043200	75	0.048
purine containing compound metabolic process	GO:0072521	253	0.047
nucleotide metabolic process	GO:0009117	279	0.047
carbohydrate derivative metabolic process	GO:1901135	346	0.046
protein complex assembly	GO:0006461	263	0.041
cation transport	GO:0006812	382	0.040
cellular component biogenesis	GO:0044085	368	0.039
regulation of cellular component organization	GO:0051128	368	0.039	Human Mouse
purine ribonucleotide catabolic process	GO:0009154	136	0.037
head development	GO:0060322	247	0.037
organelle organization	GO:0006996	266	0.037	Human
single organism intracellular transport	GO:1902582	166	0.036	Human
transmembrane transport	GO:0055085	412	0.034
negative regulation of cellular metabolic process	GO:0031324	281	0.034	Mouse
protein complex biogenesis	GO:0070271	263	0.033
positive regulation of transport	GO:0051050	245	0.033	Human
purine containing compound catabolic process	GO:0072523	138	0.033
nucleobase containing small molecule metabolic process	GO:0055086	316	0.032
negative regulation of metabolic process	GO:0009892	331	0.032	Mouse
ribonucleoside metabolic process	GO:0009119	174	0.031
ribose phosphate metabolic process	GO:0019693	235	0.030
guanosine containing compound catabolic process	GO:1901069	71	0.030
single organism carbohydrate metabolic process	GO:0044723	118	0.030
cellular response to stress	GO:0033554	269	0.030	Human
organic cyclic compound catabolic process	GO:1901361	175	0.030
guanosine containing compound metabolic process	GO:1901068	74	0.029
central nervous system development	GO:0007417	311	0.029
metal ion transport	GO:0030001	289	0.028
cytoskeleton organization	GO:0007010	111	0.028	Human
ion transmembrane transport	GO:0034220	365	0.026
chemical homeostasis	GO:0048878	292	0.026
macromolecular complex assembly	GO:0065003	273	0.025
regulation of molecular function	GO:0065009	398	0.025	Human Mouse
hexose metabolic process	GO:0019318	58	0.025
nitrogen compound transport	GO:0071705	229	0.024
ribonucleoside catabolic process	GO:0042454	126	0.024
cellular catabolic process	GO:0044248	295	0.024
glycosyl compound catabolic process	GO:1901658	126	0.024
nucleoside phosphate catabolic process	GO:1901292	140	0.024
brain development	GO:0007420	247	0.024
nucleoside phosphate metabolic process	GO:0006753	283	0.023
regulation of ion transport	GO:0043269	245	0.023
vesicle mediated transport	GO:0016192	181	0.023
nucleobase containing compound catabolic process	GO:0034655	152	0.023
gtp metabolic process	GO:0046039	72	0.022
protein localization	GO:0008104	191	0.022	Human Mouse
organophosphate catabolic process	GO:0046434	148	0.022
glycosyl compound metabolic process	GO:1901657	182	0.022
pentose metabolic process	GO:0019321	8	0.022
nucleotide catabolic process	GO:0009166	139	0.021
cellular nitrogen compound catabolic process	GO:0044270	163	0.021
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.021
response to lipopolysaccharide	GO:0032496	191	0.021
cation transmembrane transport	GO:0098655	263	0.021
golgi vesicle transport	GO:0048193	22	0.021
apoptotic process	GO:0006915	381	0.021	Human Mouse
nucleic acid templated transcription	GO:0097659	379	0.020	Human
response to wounding	GO:0009611	254	0.020
regulation of multicellular organismal development	GO:2000026	376	0.020	Human Mouse
carbohydrate catabolic process	GO:0016052	40	0.020
regulation of phosphorus metabolic process	GO:0051174	349	0.019	Mouse
neuron differentiation	GO:0030182	368	0.019	Human
ribonucleotide metabolic process	GO:0009259	231	0.019
heterocycle catabolic process	GO:0046700	167	0.019
lymphocyte activation	GO:0046649	43	0.019
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.019
positive regulation of cellular amine metabolic process	GO:0033240	3	0.019
establishment of protein localization	GO:0045184	141	0.019	Human Mouse
cell projection organization	GO:0030030	302	0.018	Human
purine ribonucleoside catabolic process	GO:0046130	124	0.018
response to nutrient	GO:0007584	248	0.018
positive regulation of molecular function	GO:0044093	230	0.018	Human Mouse
mononuclear cell proliferation	GO:0032943	29	0.018
rna biosynthetic process	GO:0032774	380	0.018	Human
purine ribonucleoside metabolic process	GO:0046128	168	0.018
carbohydrate metabolic process	GO:0005975	130	0.018
leukocyte activation	GO:0045321	76	0.017
purine ribonucleotide metabolic process	GO:0009150	227	0.017
nucleoside catabolic process	GO:0009164	126	0.016
regulation of cellular amine metabolic process	GO:0033238	8	0.016
aging	GO:0007568	241	0.016
inorganic ion transmembrane transport	GO:0098660	229	0.016
purine nucleotide catabolic process	GO:0006195	136	0.016
anion transport	GO:0006820	178	0.016
purine nucleoside catabolic process	GO:0006152	124	0.016
neuron development	GO:0048666	286	0.015	Human
nucleoside triphosphate catabolic process	GO:0009143	123	0.015
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.015
single organism organelle organization	GO:1902589	180	0.015	Human
regulation of catabolic process	GO:0009894	113	0.015
cytoplasmic transport	GO:0016482	115	0.015
regulation of protein metabolic process	GO:0051246	289	0.014	Mouse
response to extracellular stimulus	GO:0009991	380	0.014
positive regulation of multicellular organismal process	GO:0051240	387	0.014	Mouse
growth	GO:0040007	165	0.014	Mouse
ion homeostasis	GO:0050801	212	0.014
regulation of transcription dna templated	GO:0006355	374	0.014	Human
homeostatic process	GO:0042592	331	0.014
aromatic compound catabolic process	GO:0019439	168	0.014
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.014
nucleoside triphosphate metabolic process	GO:0009141	144	0.014
protein heterooligomerization	GO:0051291	89	0.014
regulation of system process	GO:0044057	208	0.014
small gtpase mediated signal transduction	GO:0007264	36	0.014
single organism carbohydrate catabolic process	GO:0044724	40	0.014
cellular chemical homeostasis	GO:0055082	247	0.014
ras protein signal transduction	GO:0007265	29	0.014
regulation of catalytic activity	GO:0050790	304	0.014	Mouse
amine metabolic process	GO:0009308	38	0.014
cellular amino acid metabolic process	GO:0006520	107	0.013
response to metal ion	GO:0010038	253	0.013
cell cell signaling	GO:0007267	335	0.013
protein oligomerization	GO:0051259	191	0.013
rna metabolic process	GO:0016070	406	0.013	Human
regulation of cellular ketone metabolic process	GO:0010565	27	0.013
leukocyte proliferation	GO:0070661	29	0.013
cellular amine metabolic process	GO:0044106	38	0.013
negative regulation of macromolecule metabolic process	GO:0010605	260	0.013	Mouse
regulation of phosphorylation	GO:0042325	248	0.013	Mouse
carboxylic acid metabolic process	GO:0019752	289	0.013
monovalent inorganic cation transport	GO:0015672	172	0.013
regulation of cellular amino acid metabolic process	GO:0006521	2	0.013
response to nutrient levels	GO:0031667	370	0.013
positive regulation of necrotic cell death	GO:0010940	4	0.013
regulation of nucleic acid templated transcription	GO:1903506	380	0.012	Human
positive regulation of cell communication	GO:0010647	271	0.012
single organism biosynthetic process	GO:0044711	342	0.012
regulation of cellular catabolic process	GO:0031329	101	0.012
immune system development	GO:0002520	41	0.012	Mouse
purine nucleoside metabolic process	GO:0042278	169	0.012
dna metabolic process	GO:0006259	96	0.012
positive regulation of developmental process	GO:0051094	283	0.012	Human Mouse
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.012
response to biotic stimulus	GO:0009607	226	0.012
reactive nitrogen species metabolic process	GO:2001057	1	0.012
positive regulation of signal transduction	GO:0009967	175	0.012
response to external biotic stimulus	GO:0043207	221	0.012
oxoacid metabolic process	GO:0043436	290	0.011
regulation of homeostatic process	GO:0032844	101	0.011
nucleoside metabolic process	GO:0009116	179	0.011
response to peptide hormone	GO:0043434	278	0.011
regulation of cell differentiation	GO:0045595	320	0.011	Human Mouse
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.011
cellular protein localization	GO:0034613	122	0.011	Human Mouse
toxin catabolic process	GO:0009407	1	0.011
negative regulation of biosynthetic process	GO:0009890	168	0.011
cellular response to oxygen containing compound	GO:1901701	386	0.011
response to insulin	GO:0032868	133	0.011
regulation of phosphate metabolic process	GO:0019220	349	0.011	Mouse
rna localization	GO:0006403	4	0.011
response to radiation	GO:0009314	137	0.011
inorganic cation transmembrane transport	GO:0098662	202	0.011
cellular macromolecule localization	GO:0070727	122	0.011	Human Mouse
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.010
cellular homeostasis	GO:0019725	252	0.010
gtp catabolic process	GO:0006184	71	0.010
regulation of homotypic cell cell adhesion	GO:0034110	4	0.010
regulation of metal ion transport	GO:0010959	118	0.010
secretion by cell	GO:0032940	248	0.010

Cib1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.018
disease of anatomical entity	DOID:7	0.018
central nervous system disease	DOID:331	0.013

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