| regulation of catalytic activity | GO:0050790 | 304 | 0.258 | |
| intracellular signal transduction | GO:0035556 | 314 | 0.205 | |
| regulation of cellular component organization | GO:0051128 | 368 | 0.194 | Worm |
| organic substance catabolic process | GO:1901575 | 316 | 0.193 | Fly |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.187 | |
| purine nucleotide metabolic process | GO:0006163 | 229 | 0.187 | |
| cellular catabolic process | GO:0044248 | 295 | 0.186 | Fly |
| actin cytoskeleton organization | GO:0030036 | 73 | 0.176 | |
| reproductive process | GO:0022414 | 372 | 0.164 | |
| protein transport | GO:0015031 | 132 | 0.163 | |
| protein phosphorylation | GO:0006468 | 345 | 0.156 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 161 | 0.153 | |
| vesicle mediated transport | GO:0016192 | 181 | 0.151 | Yeast Fly |
| nucleotide metabolic process | GO:0009117 | 279 | 0.149 | |
| locomotion | GO:0040011 | 237 | 0.146 | |
| wnt signaling pathway | GO:0016055 | 17 | 0.145 | Worm Fly |
| actin filament based movement | GO:0030048 | 16 | 0.131 | |
| catabolic process | GO:0009056 | 351 | 0.129 | Fly |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.127 | Fly |
| regulation of cellular protein metabolic process | GO:0032268 | 267 | 0.125 | Fly |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.121 | |
| macromolecule localization | GO:0033036 | 252 | 0.116 | Yeast Worm |
| purine ribonucleotide catabolic process | GO:0009154 | 136 | 0.115 | |
| rna metabolic process | GO:0016070 | 406 | 0.110 | Yeast |
| nucleoside phosphate metabolic process | GO:0006753 | 283 | 0.109 | |
| regulation of molecular function | GO:0065009 | 398 | 0.107 | |
| organophosphate metabolic process | GO:0019637 | 370 | 0.106 | |
| protein complex assembly | GO:0006461 | 263 | 0.105 | |
| signal release | GO:0023061 | 145 | 0.105 | |
| single organism organelle organization | GO:1902589 | 180 | 0.105 | Yeast Worm |
| intracellular transport | GO:0046907 | 185 | 0.105 | Yeast |
| protein localization | GO:0008104 | 191 | 0.104 | Yeast Worm |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 140 | 0.103 | |
| cellular protein localization | GO:0034613 | 122 | 0.102 | Yeast |
| transcription dna templated | GO:0006351 | 377 | 0.101 | |
| positive regulation of catalytic activity | GO:0043085 | 184 | 0.099 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.095 | |
| protein complex subunit organization | GO:0071822 | 302 | 0.093 | Worm |
| actin filament based process | GO:0030029 | 86 | 0.092 | |
| regulation of hormone levels | GO:0010817 | 187 | 0.092 | |
| purine nucleotide catabolic process | GO:0006195 | 136 | 0.091 | |
| negative regulation of cellular metabolic process | GO:0031324 | 281 | 0.091 | |
| negative regulation of response to stimulus | GO:0048585 | 155 | 0.089 | Fly |
| nucleoside monophosphate metabolic process | GO:0009123 | 93 | 0.087 | |
| organophosphate catabolic process | GO:0046434 | 148 | 0.086 | |
| regulation of protein localization | GO:0032880 | 81 | 0.085 | Worm |
| muscle system process | GO:0003012 | 115 | 0.084 | |
| neurological system process | GO:0050877 | 219 | 0.078 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.078 | |
| growth | GO:0040007 | 165 | 0.078 | |
| aromatic compound catabolic process | GO:0019439 | 168 | 0.077 | |
| carbohydrate derivative catabolic process | GO:1901136 | 147 | 0.077 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.076 | Yeast |
| cellular component assembly | GO:0022607 | 360 | 0.075 | |
| cellular macromolecule localization | GO:0070727 | 122 | 0.075 | Yeast |
| actin mediated cell contraction | GO:0070252 | 12 | 0.075 | |
| sexual reproduction | GO:0019953 | 148 | 0.073 | |
| positive regulation of response to stimulus | GO:0048584 | 285 | 0.073 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.073 | |
| nucleic acid templated transcription | GO:0097659 | 379 | 0.073 | |
| single organism intracellular transport | GO:1902582 | 166 | 0.072 | Yeast |
| anterior posterior pattern specification | GO:0009952 | 1 | 0.072 | |
| negative regulation of gene expression | GO:0010629 | 199 | 0.072 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 262 | 0.071 | |
| alternative mrna splicing via spliceosome | GO:0000380 | 4 | 0.071 | |
| purine ribonucleotide metabolic process | GO:0009150 | 227 | 0.070 | |
| organonitrogen compound catabolic process | GO:1901565 | 179 | 0.070 | |
| cell cell signaling | GO:0007267 | 335 | 0.070 | |
| ribonucleotide metabolic process | GO:0009259 | 231 | 0.069 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 148 | 0.067 | |
| positive regulation of developmental process | GO:0051094 | 283 | 0.066 | |
| regulation of cell migration | GO:0030334 | 128 | 0.066 | |
| negative regulation of metabolic process | GO:0009892 | 331 | 0.065 | |
| cell motility | GO:0048870 | 202 | 0.064 | |
| rna biosynthetic process | GO:0032774 | 380 | 0.064 | |
| ribose phosphate metabolic process | GO:0019693 | 235 | 0.064 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 167 | 0.063 | Fly |
| protein dephosphorylation | GO:0006470 | 38 | 0.062 | |
| purine nucleoside catabolic process | GO:0006152 | 124 | 0.062 | |
| regulation of signal transduction | GO:0009966 | 318 | 0.061 | Fly |
| anatomical structure morphogenesis | GO:0009653 | 298 | 0.061 | Mouse Fly |
| protein complex biogenesis | GO:0070271 | 263 | 0.060 | |
| cytoplasmic transport | GO:0016482 | 115 | 0.060 | Yeast |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 141 | 0.059 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.059 | Worm |
| circulatory system process | GO:0003013 | 183 | 0.058 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.058 | |
| axis specification | GO:0009798 | 4 | 0.058 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.058 | |
| regulation of cellular component movement | GO:0051270 | 150 | 0.057 | |
| regulation of system process | GO:0044057 | 208 | 0.057 | |
| tissue development | GO:0009888 | 252 | 0.057 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 122 | 0.057 | |
| central nervous system development | GO:0007417 | 311 | 0.056 | |
| regulation of cellular localization | GO:0060341 | 263 | 0.055 | Worm |
| nucleotide catabolic process | GO:0009166 | 139 | 0.055 | |
| reproduction | GO:0000003 | 245 | 0.055 | Yeast Worm |
| cellular response to stress | GO:0033554 | 269 | 0.055 | Yeast Fly |
| regulation of purine nucleotide metabolic process | GO:1900542 | 115 | 0.054 | |
| regulation of hydrolase activity | GO:0051336 | 143 | 0.054 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 260 | 0.054 | |
| regulation of growth | GO:0040008 | 105 | 0.053 | |
| purine containing compound metabolic process | GO:0072521 | 253 | 0.053 | |
| gtp catabolic process | GO:0006184 | 71 | 0.053 | |
| lipid metabolic process | GO:0006629 | 283 | 0.053 | |
| regulation of intracellular signal transduction | GO:1902531 | 218 | 0.052 | |
| signal transduction by phosphorylation | GO:0023014 | 144 | 0.051 | |
| regulation of cellular catabolic process | GO:0031329 | 101 | 0.050 | Fly |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 141 | 0.050 | |
| purine ribonucleoside catabolic process | GO:0046130 | 124 | 0.050 | |
| regulation of establishment of protein localization | GO:0070201 | 69 | 0.050 | |
| dendrite development | GO:0016358 | 72 | 0.050 | |
| regulation of secretion by cell | GO:1903530 | 208 | 0.049 | |
| secretion | GO:0046903 | 307 | 0.049 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 55 | 0.049 | |
| negative regulation of cell communication | GO:0010648 | 158 | 0.047 | Fly |
| single organism reproductive process | GO:0044702 | 297 | 0.047 | |
| cell projection organization | GO:0030030 | 302 | 0.047 | |
| positive regulation of protein metabolic process | GO:0051247 | 178 | 0.046 | Fly |
| ribonucleoside catabolic process | GO:0042454 | 126 | 0.046 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.046 | |
| carbohydrate derivative metabolic process | GO:1901135 | 346 | 0.046 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 122 | 0.045 | |
| positive regulation of intracellular protein transport | GO:0090316 | 20 | 0.045 | |
| positive regulation of cellular component organization | GO:0051130 | 200 | 0.045 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 144 | 0.045 | |
| macromolecular complex assembly | GO:0065003 | 273 | 0.044 | |
| response to extracellular stimulus | GO:0009991 | 380 | 0.044 | |
| actin filament organization | GO:0007015 | 42 | 0.044 | |
| nucleoside phosphate catabolic process | GO:1901292 | 140 | 0.044 | |
| purine nucleoside metabolic process | GO:0042278 | 169 | 0.043 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 141 | 0.042 | |
| muscle contraction | GO:0006936 | 88 | 0.042 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.042 | |
| regulation of neuron projection development | GO:0010975 | 161 | 0.041 | |
| positive regulation of hydrolase activity | GO:0051345 | 86 | 0.041 | |
| cardiac muscle contraction | GO:0060048 | 27 | 0.041 | |
| dendrite morphogenesis | GO:0048813 | 43 | 0.041 | |
| aging | GO:0007568 | 241 | 0.041 | |
| regulation of neuron differentiation | GO:0045664 | 208 | 0.041 | |
| negative regulation of signaling | GO:0023057 | 157 | 0.041 | Fly |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 122 | 0.040 | |
| positive regulation of signal transduction | GO:0009967 | 175 | 0.040 | |
| regulation of secretion | GO:0051046 | 224 | 0.040 | |
| regulation of nucleotide metabolic process | GO:0006140 | 117 | 0.040 | |
| protein targeting | GO:0006605 | 61 | 0.040 | |
| locomotor rhythm | GO:0045475 | 1 | 0.039 | |
| intracellular protein transport | GO:0006886 | 79 | 0.039 | |
| hormone transport | GO:0009914 | 121 | 0.039 | |
| endocytosis | GO:0006897 | 84 | 0.039 | Fly |
| circulatory system development | GO:0072359 | 134 | 0.038 | Zebrafish |
| positive regulation of phosphate metabolic process | GO:0045937 | 262 | 0.038 | |
| ribonucleotide catabolic process | GO:0009261 | 136 | 0.038 | |
| response to nutrient levels | GO:0031667 | 370 | 0.038 | |
| learning or memory | GO:0007611 | 90 | 0.038 | |
| neuron projection morphogenesis | GO:0048812 | 122 | 0.038 | |
| cellular component movement | GO:0006928 | 248 | 0.037 | |
| response to radiation | GO:0009314 | 137 | 0.037 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 84 | 0.037 | |
| regulation of hormone secretion | GO:0046883 | 106 | 0.037 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.037 | |
| neuron differentiation | GO:0030182 | 368 | 0.037 | |
| positive regulation of cell proliferation | GO:0008284 | 249 | 0.037 | |
| regulation of organelle organization | GO:0033043 | 80 | 0.036 | Worm |
| positive regulation of signaling | GO:0023056 | 270 | 0.036 | |
| response to wounding | GO:0009611 | 254 | 0.036 | |
| atp catabolic process | GO:0006200 | 54 | 0.035 | |
| single organism catabolic process | GO:0044712 | 283 | 0.035 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.035 | |
| negative regulation of biosynthetic process | GO:0009890 | 168 | 0.035 | |
| positive regulation of cell communication | GO:0010647 | 271 | 0.035 | |
| cellular component morphogenesis | GO:0032989 | 155 | 0.034 | Mouse Fly |
| nucleoside monophosphate catabolic process | GO:0009125 | 56 | 0.034 | |
| neuron development | GO:0048666 | 286 | 0.034 | |
| positive regulation of catabolic process | GO:0009896 | 78 | 0.034 | Fly |
| regulation of locomotion | GO:0040012 | 148 | 0.034 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 123 | 0.034 | |
| regulation of protein transport | GO:0051223 | 68 | 0.034 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.034 | |
| chromosome segregation | GO:0007059 | 2 | 0.033 | Yeast |
| defense response | GO:0006952 | 194 | 0.033 | |
| cellular chemical homeostasis | GO:0055082 | 247 | 0.033 | |
| synaptic growth at neuromuscular junction | GO:0051124 | 1 | 0.033 | |
| organic cyclic compound catabolic process | GO:1901361 | 175 | 0.033 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 91 | 0.033 | |
| cellular response to endogenous stimulus | GO:0071495 | 377 | 0.033 | |
| establishment of protein localization | GO:0045184 | 141 | 0.033 | |
| single organism cellular localization | GO:1902580 | 102 | 0.033 | Worm |
| negative regulation of molecular function | GO:0044092 | 133 | 0.032 | |
| glycosyl compound catabolic process | GO:1901658 | 126 | 0.032 | |
| carboxylic acid metabolic process | GO:0019752 | 289 | 0.032 | |
| cell projection morphogenesis | GO:0048858 | 123 | 0.032 | |
| gland development | GO:0048732 | 155 | 0.032 | |
| regulation of protein phosphorylation | GO:0001932 | 183 | 0.031 | |
| regulation of developmental growth | GO:0048638 | 45 | 0.031 | |
| positive regulation of gene expression | GO:0010628 | 244 | 0.031 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 118 | 0.031 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 55 | 0.031 | |
| cell morphogenesis involved in neuron differentiation | GO:0048667 | 106 | 0.031 | |
| negative regulation of transcription dna templated | GO:0045892 | 116 | 0.031 | |
| cognition | GO:0050890 | 92 | 0.031 | |
| regulation of neurogenesis | GO:0050767 | 247 | 0.031 | |
| positive regulation of intracellular signal transduction | GO:1902533 | 138 | 0.030 | |
| positive regulation of transport | GO:0051050 | 245 | 0.030 | |
| jak stat cascade | GO:0007259 | 26 | 0.030 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.030 | |
| localization of cell | GO:0051674 | 202 | 0.030 | |
| calcium ion transport | GO:0006816 | 131 | 0.030 | |
| regulation of cell motility | GO:2000145 | 131 | 0.030 | |
| protein localization to organelle | GO:0033365 | 57 | 0.030 | |
| cellular homeostasis | GO:0019725 | 252 | 0.030 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 141 | 0.029 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 84 | 0.029 | |
| regulation of cytoskeleton organization | GO:0051493 | 49 | 0.029 | Worm |
| regulation of cell projection organization | GO:0031344 | 175 | 0.029 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.029 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.029 | |
| cell part morphogenesis | GO:0032990 | 123 | 0.029 | |
| brain development | GO:0007420 | 247 | 0.029 | |
| programmed cell death | GO:0012501 | 392 | 0.029 | Worm |
| transmembrane transport | GO:0055085 | 412 | 0.029 | |
| nucleoside catabolic process | GO:0009164 | 126 | 0.028 | |
| glycosyl compound metabolic process | GO:1901657 | 182 | 0.028 | |
| negative regulation of neuron apoptotic process | GO:0043524 | 45 | 0.028 | |
| behavior | GO:0007610 | 205 | 0.028 | Fly |
| regulation of phosphorylation | GO:0042325 | 248 | 0.028 | |
| nucleocytoplasmic transport | GO:0006913 | 48 | 0.028 | |
| purine ribonucleoside metabolic process | GO:0046128 | 168 | 0.028 | |
| positive regulation of neurogenesis | GO:0050769 | 165 | 0.028 | |
| cellular protein complex assembly | GO:0043623 | 44 | 0.028 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 19 | 0.028 | Fly |
| secretion by cell | GO:0032940 | 248 | 0.028 | |
| positive regulation of actin filament polymerization | GO:0030838 | 5 | 0.027 | |
| embryonic pattern specification | GO:0009880 | 1 | 0.027 | |
| negative regulation of transport | GO:0051051 | 136 | 0.027 | |
| cellular macromolecular complex assembly | GO:0034622 | 58 | 0.027 | |
| actin myosin filament sliding | GO:0033275 | 2 | 0.027 | |
| regulation of actin filament based process | GO:0032970 | 42 | 0.027 | |
| dephosphorylation | GO:0016311 | 98 | 0.027 | |
| ion homeostasis | GO:0050801 | 212 | 0.027 | |
| positive regulation of secretion by cell | GO:1903532 | 128 | 0.027 | |
| ribonucleoside metabolic process | GO:0009119 | 174 | 0.026 | |
| regulation of anatomical structure size | GO:0090066 | 135 | 0.026 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 83 | 0.026 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 153 | 0.026 | |
| regulation of nervous system development | GO:0051960 | 264 | 0.026 | |
| hormone secretion | GO:0046879 | 115 | 0.026 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.025 | |
| golgi vesicle transport | GO:0048193 | 22 | 0.025 | Yeast |
| ras protein signal transduction | GO:0007265 | 29 | 0.025 | |
| heart contraction | GO:0060047 | 57 | 0.025 | |
| response to glucocorticoid | GO:0051384 | 223 | 0.025 | |
| cell morphogenesis | GO:0000902 | 142 | 0.025 | Mouse Fly |
| g protein coupled receptor signaling pathway | GO:0007186 | 242 | 0.025 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 55 | 0.025 | |
| regulation of cell cycle | GO:0051726 | 73 | 0.025 | Worm |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.024 | |
| small gtpase mediated signal transduction | GO:0007264 | 36 | 0.024 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 247 | 0.024 | |
| negative regulation of programmed cell death | GO:0043069 | 183 | 0.024 | |
| nuclear transport | GO:0051169 | 49 | 0.024 | |
| mapk cascade | GO:0000165 | 140 | 0.024 | |
| gamete generation | GO:0007276 | 124 | 0.024 | |
| nitrogen compound transport | GO:0071705 | 229 | 0.024 | |
| cell migration | GO:0016477 | 197 | 0.024 | |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.024 | |
| developmental growth | GO:0048589 | 100 | 0.024 | |
| striated muscle contraction | GO:0006941 | 44 | 0.024 | |
| mitotic spindle organization | GO:0007052 | 2 | 0.023 | Worm |
| positive regulation of organelle organization | GO:0010638 | 48 | 0.023 | |
| heterocycle catabolic process | GO:0046700 | 167 | 0.023 | |
| negative regulation of signal transduction | GO:0009968 | 83 | 0.023 | Fly |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.023 | |
| wound healing | GO:0042060 | 122 | 0.023 | |
| regeneration | GO:0031099 | 163 | 0.023 | |
| calcium ion homeostasis | GO:0055074 | 162 | 0.023 | |
| cardiovascular system development | GO:0072358 | 134 | 0.023 | Zebrafish |
| nucleoside metabolic process | GO:0009116 | 179 | 0.023 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 35 | 0.023 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 252 | 0.023 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 88 | 0.023 | |
| epithelium development | GO:0060429 | 96 | 0.023 | |
| multi multicellular organism process | GO:0044706 | 138 | 0.023 | |
| embryo development | GO:0009790 | 49 | 0.023 | Worm |
| cell adhesion | GO:0007155 | 110 | 0.023 | |
| regulation of protein kinase activity | GO:0045859 | 105 | 0.022 | |
| purine containing compound catabolic process | GO:0072523 | 138 | 0.022 | |
| cation transport | GO:0006812 | 382 | 0.022 | |
| regulation of cell development | GO:0060284 | 263 | 0.022 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 106 | 0.022 | |
| negative regulation of apoptotic process | GO:0043066 | 181 | 0.022 | |
| metal ion homeostasis | GO:0055065 | 186 | 0.022 | |
| regulation of protein modification process | GO:0031399 | 194 | 0.022 | |
| response to insulin | GO:0032868 | 133 | 0.022 | |
| cellular cation homeostasis | GO:0030003 | 180 | 0.022 | |
| negative regulation of rna metabolic process | GO:0051253 | 123 | 0.022 | |
| regulation of canonical wnt signaling pathway | GO:0060828 | 4 | 0.022 | |
| regulation of transferase activity | GO:0051338 | 123 | 0.022 | |
| response to oxidative stress | GO:0006979 | 186 | 0.022 | |
| protein import | GO:0017038 | 37 | 0.022 | |
| blood circulation | GO:0008015 | 183 | 0.022 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.021 | |
| sequestering of calcium ion | GO:0051208 | 8 | 0.021 | |
| regulation of dendrite development | GO:0050773 | 59 | 0.021 | |
| divalent inorganic cation homeostasis | GO:0072507 | 165 | 0.021 | |
| response to oxygen levels | GO:0070482 | 265 | 0.021 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 3 | 0.021 | |
| amine metabolic process | GO:0009308 | 38 | 0.021 | |
| regulation of response to stress | GO:0080134 | 126 | 0.021 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 163 | 0.021 | |
| immune response | GO:0006955 | 104 | 0.021 | |
| regulation of nucleotide catabolic process | GO:0030811 | 65 | 0.020 | |
| reproductive system development | GO:0061458 | 128 | 0.020 | |
| ribose phosphate biosynthetic process | GO:0046390 | 87 | 0.020 | |
| establishment of protein localization to organelle | GO:0072594 | 44 | 0.020 | |
| regulation of mrna splicing via spliceosome | GO:0048024 | 3 | 0.020 | |
| divalent metal ion transport | GO:0070838 | 132 | 0.020 | |
| regulation of homeostatic process | GO:0032844 | 101 | 0.020 | |
| regulation of blood circulation | GO:1903522 | 110 | 0.020 | |
| response to peptide hormone | GO:0043434 | 278 | 0.020 | |
| protein oligomerization | GO:0051259 | 191 | 0.020 | |
| response to growth factor | GO:0070848 | 189 | 0.020 | |
| regulation of calcium ion transport | GO:0051924 | 77 | 0.020 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 161 | 0.020 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.020 | |
| regulation of cellular component biogenesis | GO:0044087 | 86 | 0.020 | |
| protein ubiquitination | GO:0016567 | 28 | 0.020 | |
| guanosine containing compound metabolic process | GO:1901068 | 74 | 0.019 | |
| response to metal ion | GO:0010038 | 253 | 0.019 | |
| regulation of alternative mrna splicing via spliceosome | GO:0000381 | 2 | 0.019 | |
| proteolysis | GO:0006508 | 175 | 0.019 | Fly |
| regulation of kinase activity | GO:0043549 | 117 | 0.019 | |
| positive regulation of nervous system development | GO:0051962 | 178 | 0.019 | |
| response to ethanol | GO:0045471 | 162 | 0.019 | |
| cation homeostasis | GO:0055080 | 195 | 0.019 | |
| development of primary sexual characteristics | GO:0045137 | 107 | 0.019 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.019 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 119 | 0.019 | |
| organic acid metabolic process | GO:0006082 | 292 | 0.019 | |
| positive regulation of multicellular organismal process | GO:0051240 | 387 | 0.018 | |
| cellular response to hormone stimulus | GO:0032870 | 247 | 0.018 | |
| cellular lipid metabolic process | GO:0044255 | 208 | 0.018 | |
| digestive system development | GO:0055123 | 41 | 0.018 | |
| neuron projection development | GO:0031175 | 273 | 0.018 | |
| synaptic transmission | GO:0007268 | 235 | 0.018 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.018 | |
| positive regulation of phosphorylation | GO:0042327 | 177 | 0.018 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 140 | 0.018 | |
| negative regulation of multicellular organismal process | GO:0051241 | 203 | 0.018 | |
| regulation of peptide secretion | GO:0002791 | 82 | 0.018 | |
| positive regulation of cellular catabolic process | GO:0031331 | 71 | 0.018 | Fly |
| maintenance of location | GO:0051235 | 17 | 0.018 | Yeast |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 162 | 0.018 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 167 | 0.018 | |
| negative regulation of cellular component organization | GO:0051129 | 83 | 0.018 | |
| cellular response to organonitrogen compound | GO:0071417 | 197 | 0.018 | |
| memory | GO:0007613 | 54 | 0.017 | |
| nucleobase containing compound catabolic process | GO:0034655 | 152 | 0.017 | |
| response to toxic substance | GO:0009636 | 133 | 0.017 | |
| response to cytokine | GO:0034097 | 215 | 0.017 | |
| single organism behavior | GO:0044708 | 130 | 0.017 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 27 | 0.017 | |
| axonogenesis | GO:0007409 | 71 | 0.017 | |
| organelle organization | GO:0006996 | 266 | 0.017 | Yeast Worm |
| cellular response to external stimulus | GO:0071496 | 118 | 0.017 | |
| regulation of cellular component size | GO:0032535 | 51 | 0.017 | |
| cellular ketone metabolic process | GO:0042180 | 51 | 0.017 | |
| response to decreased oxygen levels | GO:0036293 | 237 | 0.017 | |
| regulation of mapk cascade | GO:0043408 | 116 | 0.017 | |
| cellular response to alcohol | GO:0097306 | 87 | 0.017 | |
| protein polymerization | GO:0051258 | 22 | 0.017 | |
| negative regulation of cell differentiation | GO:0045596 | 99 | 0.017 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 1 | 0.017 | |
| cellular response to steroid hormone stimulus | GO:0071383 | 93 | 0.016 | |
| negative regulation of catalytic activity | GO:0043086 | 103 | 0.016 | |
| positive regulation of neuron differentiation | GO:0045666 | 126 | 0.016 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 117 | 0.016 | |
| purine containing compound biosynthetic process | GO:0072522 | 85 | 0.016 | |
| chemical homeostasis | GO:0048878 | 292 | 0.016 | |
| positive regulation of transferase activity | GO:0051347 | 81 | 0.016 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 2 | 0.016 | |
| cellular ion homeostasis | GO:0006873 | 184 | 0.016 | |
| response to inorganic substance | GO:0010035 | 377 | 0.016 | |
| response to carbohydrate | GO:0009743 | 183 | 0.016 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 80 | 0.016 | |
| purine ribonucleotide biosynthetic process | GO:0009152 | 81 | 0.016 | |
| neuron apoptotic process | GO:0051402 | 88 | 0.016 | |
| organ regeneration | GO:0031100 | 101 | 0.016 | |
| cellular response to organic cyclic compound | GO:0071407 | 202 | 0.016 | |
| homeostatic process | GO:0042592 | 331 | 0.016 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.016 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 65 | 0.016 | |
| nucleotide biosynthetic process | GO:0009165 | 98 | 0.016 | |
| hormone metabolic process | GO:0042445 | 69 | 0.015 | |
| positive regulation of peptide secretion | GO:0002793 | 52 | 0.015 | |
| actin polymerization or depolymerization | GO:0008154 | 14 | 0.015 | |
| response to peptide | GO:1901652 | 292 | 0.015 | |
| negative regulation of developmental process | GO:0051093 | 125 | 0.015 | |
| protein heterooligomerization | GO:0051291 | 89 | 0.015 | |
| mesoderm development | GO:0007498 | 2 | 0.015 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 102 | 0.015 | |
| gtp metabolic process | GO:0046039 | 72 | 0.015 | |
| apoptotic process | GO:0006915 | 381 | 0.015 | Worm |
| positive regulation of cell projection organization | GO:0031346 | 111 | 0.015 | |
| protein homooligomerization | GO:0051260 | 91 | 0.015 | |
| regulation of neuron death | GO:1901214 | 115 | 0.015 | |
| response to glucose | GO:0009749 | 136 | 0.015 | |
| positive regulation of cell motility | GO:2000147 | 97 | 0.015 | |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.015 | |
| positive regulation of protein phosphorylation | GO:0001934 | 135 | 0.014 | |
| camp metabolic process | GO:0046058 | 63 | 0.014 | |
| heart process | GO:0003015 | 57 | 0.014 | |
| cytoskeleton organization | GO:0007010 | 111 | 0.014 | Yeast Worm |
| positive regulation of cytosolic calcium ion concentration | GO:0007204 | 122 | 0.014 | |
| muscle structure development | GO:0061061 | 87 | 0.014 | |
| non canonical wnt signaling pathway | GO:0035567 | 3 | 0.014 | Worm |
| negative regulation of phosphate metabolic process | GO:0045936 | 80 | 0.014 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.014 | |
| organic hydroxy compound metabolic process | GO:1901615 | 115 | 0.014 | |
| response to ammonium ion | GO:0060359 | 71 | 0.014 | |
| positive regulation of cytoskeleton organization | GO:0051495 | 26 | 0.014 | |
| response to transition metal nanoparticle | GO:1990267 | 122 | 0.014 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.014 | |
| learning | GO:0007612 | 33 | 0.014 | |
| regulation of peptide hormone secretion | GO:0090276 | 80 | 0.014 | |
| response to interleukin 13 | GO:0035962 | 3 | 0.014 | |
| reproductive structure development | GO:0048608 | 128 | 0.014 | |
| single organism biosynthetic process | GO:0044711 | 342 | 0.014 | |
| neuron death | GO:0070997 | 127 | 0.013 | |
| response to hypoxia | GO:0001666 | 231 | 0.013 | |
| guanosine containing compound catabolic process | GO:1901069 | 71 | 0.013 | |
| embryonic axis specification | GO:0000578 | 1 | 0.013 | |
| macromolecule catabolic process | GO:0009057 | 58 | 0.013 | Fly |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 234 | 0.013 | |
| heart development | GO:0007507 | 72 | 0.013 | Zebrafish |
| positive regulation of cell development | GO:0010720 | 176 | 0.013 | |
| hormone mediated signaling pathway | GO:0009755 | 23 | 0.013 | |
| actin filament bundle organization | GO:0061572 | 19 | 0.013 | |
| response to bacterium | GO:0009617 | 200 | 0.013 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 53 | 0.013 | |
| sensory perception | GO:0007600 | 101 | 0.013 | |
| regulation of smooth muscle cell proliferation | GO:0048660 | 75 | 0.013 | |
| activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway | GO:0097296 | 1 | 0.013 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 32 | 0.013 | |
| tissue morphogenesis | GO:0048729 | 22 | 0.013 | |
| regulation of ion transport | GO:0043269 | 245 | 0.013 | |
| gastrulation | GO:0007369 | 2 | 0.013 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 91 | 0.013 | |
| urogenital system development | GO:0001655 | 78 | 0.013 | |
| mitotic cell cycle | GO:0000278 | 49 | 0.013 | Yeast Worm |
| lipid storage | GO:0019915 | 1 | 0.012 | |
| regulation of programmed cell death | GO:0043067 | 341 | 0.012 | |
| regulation of neuron apoptotic process | GO:0043523 | 83 | 0.012 | |
| regulation of muscle system process | GO:0090257 | 79 | 0.012 | |
| amide transport | GO:0042886 | 105 | 0.012 | |
| positive regulation of locomotion | GO:0040017 | 102 | 0.012 | |
| spindle organization | GO:0007051 | 2 | 0.012 | Worm |
| negative regulation of protein metabolic process | GO:0051248 | 114 | 0.012 | |
| cytokine production | GO:0001816 | 61 | 0.012 | |
| lipid biosynthetic process | GO:0008610 | 128 | 0.012 | |
| microtubule organizing center organization | GO:0031023 | 1 | 0.012 | |
| g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger | GO:0007187 | 55 | 0.012 | |
| response to ketone | GO:1901654 | 182 | 0.012 | |
| cellular response to peptide | GO:1901653 | 133 | 0.012 | |
| positive regulation of protein transport | GO:0051222 | 41 | 0.012 | |
| cellular response to lipid | GO:0071396 | 201 | 0.012 | |
| positive regulation of insulin secretion | GO:0032024 | 36 | 0.012 | |
| circadian rhythm | GO:0007623 | 88 | 0.012 | |
| cell activation | GO:0001775 | 97 | 0.012 | |
| positive regulation of peptide hormone secretion | GO:0090277 | 50 | 0.012 | |
| biological adhesion | GO:0022610 | 110 | 0.012 | |
| regulation of insulin secretion | GO:0050796 | 65 | 0.011 | |
| protein modification by small protein conjugation | GO:0032446 | 31 | 0.011 | |
| morphogenesis of an epithelium | GO:0002009 | 20 | 0.011 | |
| organophosphate biosynthetic process | GO:0090407 | 143 | 0.011 | |
| negative regulation of cell death | GO:0060548 | 229 | 0.011 | |
| positive regulation of cell death | GO:0010942 | 184 | 0.011 | |
| regulation of stem cell differentiation | GO:2000736 | 2 | 0.011 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 53 | 0.011 | |
| response to antibiotic | GO:0046677 | 39 | 0.011 | |
| response to alkaloid | GO:0043279 | 132 | 0.011 | |
| male sex differentiation | GO:0046661 | 64 | 0.011 | |
| protein import into nucleus | GO:0006606 | 35 | 0.011 | |
| cellular response to nutrient levels | GO:0031669 | 60 | 0.011 | |
| cell cycle process | GO:0022402 | 57 | 0.011 | Yeast Worm |
| rna localization | GO:0006403 | 4 | 0.011 | |
| regulation of smooth muscle cell migration | GO:0014910 | 36 | 0.011 | |
| negative regulation of secretion by cell | GO:1903531 | 72 | 0.011 | |
| meiotic cell cycle process | GO:1903046 | 3 | 0.011 | Yeast |
| regulation of nucleoside metabolic process | GO:0009118 | 66 | 0.011 | |
| response to hexose | GO:0009746 | 144 | 0.011 | |
| adenylate cyclase activating g protein coupled receptor signaling pathway | GO:0007189 | 24 | 0.011 | |
| adenylate cyclase modulating g protein coupled receptor signaling pathway | GO:0007188 | 51 | 0.011 | |
| ribonucleotide biosynthetic process | GO:0009260 | 85 | 0.011 | |
| adult locomotory behavior | GO:0008344 | 4 | 0.011 | |
