Rattus norvegicus

88 known processes

Unc13b

unc-13 homolog B (C. elegans)

(Aliases: Unc13h2,Munc13-2)

Unc13b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
apoptotic processGO:00069153810.217
positive regulation of multicellular organismal processGO:00512403870.212
programmed cell deathGO:00125013920.190
cellular component movementGO:00069282480.158
protein complex subunit organizationGO:00718223020.151
rhythmic processGO:00485111560.147
organelle organizationGO:00069962660.144
cellular component biogenesisGO:00440853680.138
regulation of cellular component organizationGO:00511283680.128
cell cell signalingGO:00072673350.127
cell projection organizationGO:00300303020.125
positive regulation of secretionGO:00510471400.116
transcription dna templatedGO:00063513770.114
locomotionGO:00400112370.114
regulation of molecular functionGO:00650093980.113
anatomical structure morphogenesisGO:00096532980.106
single organism organelle organizationGO:19025891800.106
transmembrane transportGO:00550854120.101
carbohydrate derivative metabolic processGO:19011353460.101
regulation of programmed cell deathGO:00430673410.100
behaviorGO:00076102050.100
regulation of catalytic activityGO:00507903040.096
agingGO:00075682410.095
neurological system processGO:00508772190.093
neuron differentiationGO:00301823680.092
cation transportGO:00068123820.092
organophosphate metabolic processGO:00196373700.092
cellular component assemblyGO:00226073600.091
regulation of signal transductionGO:00099663180.091
synaptic transmissionGO:00072682350.090
regulation of phosphorus metabolic processGO:00511743490.088
regulation of cell proliferationGO:00421273590.086
neuron projection developmentGO:00311752730.086
regulation of cellular component movementGO:00512701500.086
regulation of transcription dna templatedGO:00063553740.085
regulation of phosphate metabolic processGO:00192203490.084
oxoacid metabolic processGO:00434362900.083
rna metabolic processGO:00160704060.083
protein complex assemblyGO:00064612630.082
cell migrationGO:00164771970.081
macromolecule localizationGO:00330362520.081
positive regulation of nucleobase containing compound metabolic processGO:00459353190.081
regulation of rna biosynthetic processGO:20011413810.080
protein localizationGO:00081041910.079
regulation of multicellular organismal developmentGO:20000263760.076
regulation of cell differentiationGO:00455953200.074
positive regulation of nucleotide metabolic processGO:0045981910.072
regulation of nervous system developmentGO:00519602640.071
multicellular organismal reproductive processGO:00486092330.070
cellular component morphogenesisGO:00329891550.069
single organism behaviorGO:00447081300.069
tissue developmentGO:00098882520.069
purine containing compound metabolic processGO:00725212530.068
metal ion transportGO:00300012890.067
regulation of apoptotic processGO:00429813350.067
cell motilityGO:00488702020.067
nucleotide metabolic processGO:00091172790.066
purine ribonucleotide metabolic processGO:00091502270.066
ion transmembrane transportGO:00342203650.065
nucleoside triphosphate catabolic processGO:00091431230.065
cellular catabolic processGO:00442482950.064
positive regulation of cellular biosynthetic processGO:00313282950.063
cell morphogenesis involved in neuron differentiationGO:00486671060.063
positive regulation of developmental processGO:00510942830.061
regulation of locomotionGO:00400121480.061
nucleic acid templated transcriptionGO:00976593790.061
intracellular signal transductionGO:00355563140.061
regulation of nucleic acid templated transcriptionGO:19035063800.060
monovalent inorganic cation transportGO:00156721720.060
positive regulation of nitrogen compound metabolic processGO:00511733340.060
protein complex biogenesisGO:00702712630.059
biological adhesionGO:00226101100.059
macromolecular complex subunit organizationGO:00439333390.058
response to estrogenGO:00436272320.058
neuron developmentGO:00486662860.057
cell morphogenesisGO:00009021420.056
positive regulation of rna metabolic processGO:00512542030.056
blood circulationGO:00080151830.056
rna biosynthetic processGO:00327743800.056
homeostatic processGO:00425923310.056
response to purine containing compoundGO:00140741260.056
positive regulation of response to stimulusGO:00485842850.055
cytoskeleton organizationGO:00070101110.055
circulatory system processGO:00030131830.055
response to metal ionGO:00100382530.055
positive regulation of biosynthetic processGO:00098913190.054
positive regulation of gene expressionGO:00106282440.053
sexual reproductionGO:00199531480.053
heart morphogenesisGO:000300730.052
secretion by cellGO:00329402480.052
positive regulation of cell communicationGO:00106472710.052
positive regulation of molecular functionGO:00440932300.052
aromatic compound catabolic processGO:00194391680.052
central nervous system developmentGO:00074173110.051
positive regulation of signalingGO:00230562700.051
response to radiationGO:00093141370.051
response to inorganic substanceGO:00100353770.051
localization of cellGO:00516742020.051
cellular response to endogenous stimulusGO:00714953770.050
multi organism reproductive processGO:00447032620.050
carboxylic acid metabolic processGO:00197522890.050
reproductive processGO:00224143720.050
metal ion homeostasisGO:00550651860.049
developmental process involved in reproductionGO:00030061590.049
axon developmentGO:0061564960.049
positive regulation of cellular component organizationGO:00511302000.048
negative regulation of programmed cell deathGO:00430691830.048
ribonucleotide metabolic processGO:00092592310.048
purine ribonucleoside metabolic processGO:00461281680.048
regulation of cellular localizationGO:00603412630.048
regulation of hydrolase activityGO:00513361430.048
regulation of system processGO:00440572080.048
positive regulation of transportGO:00510502450.047
cell part morphogenesisGO:00329901230.047
single organism reproductive processGO:00447022970.047
neuron projection morphogenesisGO:00488121220.047
organic acid metabolic processGO:00060822920.046
divalent inorganic cation transportGO:00725111340.046
nucleobase containing small molecule metabolic processGO:00550863160.046
macromolecular complex assemblyGO:00650032730.046
cellular chemical homeostasisGO:00550822470.046
positive regulation of cell proliferationGO:00082842490.046
protein transportGO:00150311320.045
organic substance catabolic processGO:19015753160.045
membrane organizationGO:0061024940.045
regulation of neurogenesisGO:00507672470.045
vesicle mediated transportGO:00161921810.045
regulation of ion transportGO:00432692450.045
regulation of ion transmembrane transportGO:00347651210.045
development of primary sexual characteristicsGO:00451371070.044
synaptic growth at neuromuscular junctionGO:005112410.044
purine nucleotide metabolic processGO:00061632290.044
growthGO:00400071650.043
regulation of rna metabolic processGO:00512523910.043
regulation of synaptic transmissionGO:00508041410.043
neurotransmitter transportGO:0006836420.043
nucleoside phosphate metabolic processGO:00067532830.043
response to alkaloidGO:00432791320.043
positive regulation of phosphate metabolic processGO:00459372620.043
regulation of secretionGO:00510462240.042
positive regulation of programmed cell deathGO:00430681570.042
positive regulation of macromolecule biosynthetic processGO:00105572470.041
cellular macromolecule localizationGO:00707271220.041
regulation of response to stressGO:00801341260.041
potassium ion transportGO:0006813970.041
regulation of nucleotide metabolic processGO:00061401170.041
positive regulation of phosphorus metabolic processGO:00105622620.041
cellular cation homeostasisGO:00300031800.041
regulation of transporter activityGO:0032409500.041
negative regulation of cell deathGO:00605482290.040
regulation of transcription from rna polymerase ii promoterGO:00063572340.040
epithelium developmentGO:0060429960.040
multicellular organism reproductionGO:00325042330.040
single organism biosynthetic processGO:00447113420.040
cell projection morphogenesisGO:00488581230.040
developmental growthGO:00485891000.039
single organism catabolic processGO:00447122830.039
small gtpase mediated signal transductionGO:0007264360.039
regulation of response to external stimulusGO:00321011060.039
ribose phosphate metabolic processGO:00196932350.039
response to peptideGO:19016522920.038
cell adhesionGO:00071551100.038
positive regulation of nucleoside metabolic processGO:0045979550.038
organic cyclic compound catabolic processGO:19013611750.038
taxisGO:0042330670.038
purine ribonucleotide catabolic processGO:00091541360.038
positive regulation of cell motilityGO:2000147970.038
ribonucleoside metabolic processGO:00091191740.037
glycosyl compound metabolic processGO:19016571820.037
cellular homeostasisGO:00197252520.036
establishment of protein localizationGO:00451841410.036
response to nutrient levelsGO:00316673700.036
cellular lipid metabolic processGO:00442552080.036
head developmentGO:00603222470.036
cellular amino acid metabolic processGO:00065201070.036
divalent inorganic cation homeostasisGO:00725071650.036
response to hypoxiaGO:00016662310.036
guanosine containing compound metabolic processGO:1901068740.036
lipid metabolic processGO:00066292830.036
positive regulation of rna biosynthetic processGO:19026801970.036
cellular ion homeostasisGO:00068731840.036
transcription from rna polymerase ii promoterGO:00063662520.036
purine nucleoside metabolic processGO:00422781690.036
nucleoside metabolic processGO:00091161790.035
nucleobase containing compound catabolic processGO:00346551520.035
cellular metal ion homeostasisGO:00068751720.035
catabolic processGO:00090563510.035
heterocycle catabolic processGO:00467001670.034
intracellular transportGO:00469071850.034
purine containing compound catabolic processGO:00725231380.034
positive regulation of cell differentiationGO:00455972170.034
negative regulation of transportGO:00510511360.034
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.034
secretionGO:00469033070.034
nucleoside triphosphate metabolic processGO:00091411440.034
actin filament based processGO:0030029860.034
regulation of phosphorylationGO:00423252480.034
ras protein signal transductionGO:0007265290.033
response to woundingGO:00096112540.033
female gonad developmentGO:0008585530.033
axonogenesisGO:0007409710.033
regulation of organelle organizationGO:0033043800.033
calcium ion homeostasisGO:00550741620.033
negative regulation of cellular metabolic processGO:00313242810.033
ribonucleoside catabolic processGO:00424541260.033
learning or memoryGO:0007611900.033
cell morphogenesis involved in differentiationGO:00009041190.033
forebrain developmentGO:0030900980.033
response to decreased oxygen levelsGO:00362932370.032
negative regulation of apoptotic processGO:00430661810.032
regulation of cell developmentGO:00602842630.032
brain developmentGO:00074202470.032
circulatory system developmentGO:00723591340.032
actin cytoskeleton organizationGO:0030036730.032
regulation of cell migrationGO:00303341280.032
amine metabolic processGO:0009308380.032
cellular response to stressGO:00335542690.032
regulation of transmembrane transportGO:00347621220.032
reproductionGO:00000032450.031
purine ribonucleoside triphosphate metabolic processGO:00092051400.031
positive regulation of nucleic acid templated transcriptionGO:19035081970.031
negative regulation of gene expressionGO:00106291990.031
negative regulation of multicellular organismal processGO:00512412030.031
response to oxygen levelsGO:00704822650.031
regulation of cell motilityGO:20001451310.031
positive regulation of gtpase activityGO:0043547470.031
chemical homeostasisGO:00488782920.031
ion homeostasisGO:00508012120.031
divalent metal ion transportGO:00708381320.031
negative regulation of nitrogen compound metabolic processGO:00511721610.031
regulation of neuron deathGO:19012141150.030
organonitrogen compound catabolic processGO:19015651790.030
cell type specific apoptotic processGO:00972851340.030
sex differentiationGO:00075481130.030
ovulation cycle processGO:0022602500.029
cellular nitrogen compound catabolic processGO:00442701630.029
nucleotide catabolic processGO:00091661390.029
response to acid chemicalGO:00011012220.029
negative regulation of cellular component organizationGO:0051129830.029
positive regulation of catalytic activityGO:00430851840.028
positive regulation of hydrolase activityGO:0051345860.028
ribonucleotide catabolic processGO:00092611360.028
establishment of organelle localizationGO:0051656370.028
response to oxidative stressGO:00069791860.028
response to fatty acidGO:0070542650.028
nucleoside phosphate catabolic processGO:19012921400.028
cellular response to oxygen containing compoundGO:19017013860.028
positive regulation of purine nucleotide metabolic processGO:1900544910.028
cellular amine metabolic processGO:0044106380.027
positive regulation of transcription dna templatedGO:00458931970.027
regulation of behaviorGO:0050795610.027
regulation of hormone levelsGO:00108171870.027
negative regulation of metabolic processGO:00098923310.027
neurotransmitter secretionGO:0007269330.027
synaptic vesicle primingGO:001608240.027
synaptic vesicle endocytosisGO:004848840.026
proteolysisGO:00065081750.026
regulation of purine nucleotide metabolic processGO:19005421150.026
reproductive structure developmentGO:00486081280.026
negative regulation of macromolecule metabolic processGO:00106052600.025
single organism intracellular transportGO:19025821660.025
cellular response to cytokine stimulusGO:00713451270.025
response to organophosphorusGO:00466831020.025
response to corticosteroidGO:00319602350.025
cellular response to organonitrogen compoundGO:00714171970.025
protein phosphorylationGO:00064683450.025
negative regulation of molecular functionGO:00440921330.025
regulation of cell projection organizationGO:00313441750.025
response to glucocorticoidGO:00513842230.025
nucleoside catabolic processGO:00091641260.025
purine nucleoside triphosphate catabolic processGO:00091461220.025
nitrogen compound transportGO:00717052290.025
mesoderm developmentGO:000749820.024
regulation of secretion by cellGO:19035302080.024
response to monosaccharideGO:00342841590.024
positive regulation of cellular component movementGO:00512721020.024
response to cytokineGO:00340972150.024
cellular response to hormone stimulusGO:00328702470.024
inorganic cation transmembrane transportGO:00986622020.024
gtp catabolic processGO:0006184710.024
response to lipopolysaccharideGO:00324961910.024
regulation of cellular amine metabolic processGO:003323880.024
response to carbohydrateGO:00097431830.024
purine nucleotide catabolic processGO:00061951360.024
regulation of catabolic processGO:00098941130.023
regulation of smooth muscle cell proliferationGO:0048660750.023
regulation of gtpase activityGO:0043087570.023
positive regulation of gtp catabolic processGO:0033126480.023
regulation of heart contractionGO:0008016480.023
establishment of vesicle localizationGO:0051650310.023
cellular ketone metabolic processGO:0042180510.023
purine ribonucleoside triphosphate catabolic processGO:00092071220.023
positive regulation of smooth muscle cell proliferationGO:0048661510.023
positive regulation of cell projection organizationGO:00313461110.022
single organism carbohydrate metabolic processGO:00447231180.022
positive regulation of secretion by cellGO:19035321280.022
positive regulation of nucleotide catabolic processGO:0030813530.022
adult locomotory behaviorGO:000834440.022
cellular hormone metabolic processGO:0034754490.022
cation transmembrane transportGO:00986552630.022
regulation of neuron differentiationGO:00456642080.022
gamete generationGO:00072761240.022
regulation of cell adhesionGO:0030155520.022
carbohydrate derivative catabolic processGO:19011361470.022
response to temperature stimulusGO:0009266940.022
regulation of membrane potentialGO:00423911100.022
positive regulation of cell migrationGO:0030335960.022
positive regulation of locomotionGO:00400171020.022
circadian rhythmGO:0007623880.022
response to extracellular stimulusGO:00099913800.022
organophosphate biosynthetic processGO:00904071430.022
inflammatory responseGO:00069541500.022
g protein coupled receptor signaling pathwayGO:00071862420.022
positive regulation of signal transductionGO:00099671750.022
organic hydroxy compound metabolic processGO:19016151150.022
carbohydrate derivative biosynthetic processGO:19011371240.021
regulation of axonogenesisGO:0050770370.021
immune responseGO:00069551040.021
purine ribonucleoside catabolic processGO:00461301240.021
cell activationGO:0001775970.021
amide transportGO:00428861050.021
calcium ion transportGO:00068161310.021
regulation of body fluid levelsGO:0050878900.021
response to glucoseGO:00097491360.021
carbohydrate metabolic processGO:00059751300.021
regulation of cytoskeleton organizationGO:0051493490.021
multi multicellular organism processGO:00447061380.021
regulation of anatomical structure morphogenesisGO:00226031410.021
regulation of cellular ketone metabolic processGO:0010565270.021
regulation of ion transmembrane transporter activityGO:0032412480.021
response to biotic stimulusGO:00096072260.021
regulation of protein modification processGO:00313991940.021
exocytosisGO:0006887600.021
cognitionGO:0050890920.021
regulation of purine nucleotide catabolic processGO:0033121650.021
positive regulation of ras gtpase activityGO:0032320280.021
single organism membrane organizationGO:0044802740.021
purine nucleoside catabolic processGO:00061521240.021
protein maturationGO:0051604680.020
gastrulationGO:000736920.020
positive regulation of cellular catabolic processGO:0031331710.020
regulation of anatomical structure sizeGO:00900661350.020
memoryGO:0007613540.020
protein oligomerizationGO:00512591910.020
response to external biotic stimulusGO:00432072210.020
positive regulation of cell developmentGO:00107201760.020
purine nucleoside triphosphate metabolic processGO:00091441410.020
cellular divalent inorganic cation homeostasisGO:00725031620.020
response to campGO:0051591910.020
dendrite developmentGO:0016358720.020
cation homeostasisGO:00550801950.019
immune system processGO:00023762040.019
negative regulation of cell proliferationGO:00082851190.019
receptor mediated endocytosisGO:0006898420.019
ribonucleoside triphosphate catabolic processGO:00092031220.019
positive regulation of nervous system developmentGO:00519621780.019
regulation of growthGO:00400081050.019
response to calcium ionGO:0051592590.019
muscle cell proliferationGO:0033002840.019
response to ethanolGO:00454711620.019
synaptic vesicle transportGO:0048489230.019
signal releaseGO:00230611450.019
b cell differentiationGO:003018320.019
organophosphate catabolic processGO:00464341480.019
response to nutrientGO:00075842480.019
regulation of protein metabolic processGO:00512462890.019
guanosine containing compound catabolic processGO:1901069710.019
cellular response to organic cyclic compoundGO:00714072020.018
positive regulation of protein modification processGO:00314011420.018
protein autophosphorylationGO:0046777660.018
regulation of response to woundingGO:1903034690.018
dephosphorylationGO:0016311980.018
regulation of blood circulationGO:19035221100.018
axis specificationGO:000979840.018
regulation of nucleotide catabolic processGO:0030811650.018
neuron apoptotic processGO:0051402880.018
response to amino acidGO:0043200750.018
alcohol metabolic processGO:0006066770.018
inorganic ion transmembrane transportGO:00986602290.018
cytosolic calcium ion homeostasisGO:00514801400.018
regulation of protein phosphorylationGO:00019321830.017
response to peptide hormoneGO:00434342780.017
embryonic pattern specificationGO:000988010.017
response to ketoneGO:19016541820.017
cellular carbohydrate metabolic processGO:0044262720.017
regulation of neurotransmitter levelsGO:0001505420.017
regulation of nucleoside metabolic processGO:0009118660.017
ribonucleoside triphosphate metabolic processGO:00091991410.017
vesicle localizationGO:0051648330.017
positive regulation of cytosolic calcium ion concentrationGO:00072041220.017
cellular protein localizationGO:00346131220.017
peptide secretionGO:0002790860.017
regulation of cellular amino acid metabolic processGO:000652120.017
positive regulation of cell deathGO:00109421840.017
response to hydrogen peroxideGO:0042542890.017
sodium ion transportGO:0006814820.017
positive regulation of phosphorylationGO:00423271770.017
muscle system processGO:00030121150.017
endomembrane system organizationGO:0010256480.017
cellular response to nitrogen compoundGO:19016992100.016
cellular calcium ion homeostasisGO:00068741600.016
negative regulation of response to stimulusGO:00485851550.016
positive regulation of neurogenesisGO:00507691650.016
reactive oxygen species metabolic processGO:0072593370.016
l glutamate importGO:005193820.016
heart developmentGO:0007507720.016
oxidation reduction processGO:00551143040.016
regenerationGO:00310991630.016
development of primary female sexual characteristicsGO:0046545560.016
female sex differentiationGO:0046660590.016
cellular response to growth factor stimulusGO:00713631620.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
regulation of small gtpase mediated signal transductionGO:0051056480.016
protein homooligomerizationGO:0051260910.016
cytoplasmic transportGO:00164821150.016
regulation of neuron projection developmentGO:00109751610.016
anion transportGO:00068201780.015
glycerolipid metabolic processGO:0046486670.015
response to insulinGO:00328681330.015
cell cycle checkpointGO:000007520.015
positive regulation of purine nucleotide catabolic processGO:0033123530.015
embryo developmentGO:0009790490.015
response to hexoseGO:00097461440.015
positive regulation of cellular amine metabolic processGO:003324030.015
rho protein signal transductionGO:0007266110.015
cellular amide metabolic processGO:0043603440.015
regulation of rab protein signal transductionGO:003248330.015
organic anion transportGO:00157111320.015
heart processGO:0003015570.015
lipid modificationGO:0030258520.015
reactive oxygen species biosynthetic processGO:190340980.015
organonitrogen compound biosynthetic processGO:19015661670.015
response to growth factorGO:00708481890.015
organ morphogenesisGO:0009887750.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
positive regulation of ion transportGO:0043270940.015
multicellular organism growthGO:003526410.015
neuron deathGO:00709971270.014
regulation of cell growthGO:0001558850.014
regulation of neuron apoptotic processGO:0043523830.014
negative regulation of cellular biosynthetic processGO:00313271610.014
defense responseGO:00069521940.014
small molecule biosynthetic processGO:00442831240.014
positive regulation of intracellular signal transductionGO:19025331380.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
actin mediated cell contractionGO:0070252120.014
glycosyl compound catabolic processGO:19016581260.014
positive regulation of protein metabolic processGO:00512471780.014
negative regulation of neuron apoptotic processGO:0043524450.014
peptide transportGO:0015833970.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.014
cell cycleGO:00070491010.014
circadian regulation of gene expressionGO:003292230.014
cellular response to glucocorticoid stimulusGO:0071385680.014
positive regulation of catabolic processGO:0009896780.014
insulin secretionGO:0030073690.014
hormone metabolic processGO:0042445690.014
endocytosisGO:0006897840.014
blood coagulationGO:0007596260.014
anterior posterior pattern specificationGO:000995210.014
sensory perceptionGO:00076001010.014
regulation of protein localizationGO:0032880810.013
anatomical structure formation involved in morphogenesisGO:0048646830.013
nucleoside monophosphate metabolic processGO:0009123930.013
morphogenesis of a polarized epitheliumGO:000173810.013
glutamate receptor signaling pathwayGO:0007215430.013
positive regulation of rho gtpase activityGO:0032321130.013
leukocyte activationGO:0045321760.013
single organismal cell cell adhesionGO:0016337420.013
regulation of developmental growthGO:0048638450.013
chemotaxisGO:0006935660.013
cytoskeleton dependent cytokinesisGO:006164020.013
response to tumor necrosis factorGO:0034612560.013
multicellular organismal signalingGO:0035637440.013
regulation of homeostatic processGO:00328441010.013
neuromuscular synaptic transmissionGO:000727420.013
negative regulation of protein metabolic processGO:00512481140.013
regulation of cellular component biogenesisGO:0044087860.013
chromosome segregationGO:000705920.013
signal transduction by phosphorylationGO:00230141440.013
cellular response to lipidGO:00713962010.013

Unc13b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
nervous system diseaseDOID:86300.043
musculoskeletal system diseaseDOID:1700.035
cancerDOID:16200.024
disease of cellular proliferationDOID:1456600.024
muscular diseaseDOID:008000000.023
central nervous system diseaseDOID:33100.023
eye and adnexa diseaseDOID:149200.021
sensory system diseaseDOID:005015500.021
eye diseaseDOID:561400.021
retinal diseaseDOID:567900.021
muscle tissue diseaseDOID:6600.019
organ system cancerDOID:005068600.018
myopathyDOID:42300.014