Rattus norvegicus

0 known processes

Arhgef5

Rho guanine nucleotide exchange factor (GEF) 5

(Aliases: Tim1)

Arhgef5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of signal transductionGO:00099663180.072
Rat
transcription dna templatedGO:00063513770.067
regulation of protein metabolic processGO:00512462890.066
organic acid metabolic processGO:00060822920.062
nucleic acid templated transcriptionGO:00976593790.062
regulation of phosphorylationGO:00423252480.062
negative regulation of metabolic processGO:00098923310.062
regulation of protein modification processGO:00313991940.060
positive regulation of cell communicationGO:00106472710.058
cellular component assemblyGO:00226073600.054
Rat
regulation of rna metabolic processGO:00512523910.053
protein phosphorylationGO:00064683450.051
apoptotic processGO:00069153810.050
negative regulation of cellular metabolic processGO:00313242810.050
rna biosynthetic processGO:00327743800.048
negative regulation of macromolecule metabolic processGO:00106052600.046
regulation of transcription dna templatedGO:00063553740.046
regulation of phosphate metabolic processGO:00192203490.045
Rat
regulation of cellular component organizationGO:00511283680.045
Rat
regulation of nucleic acid templated transcriptionGO:19035063800.044
intracellular signal transductionGO:00355563140.043
regulation of programmed cell deathGO:00430673410.043
regulation of cellular ketone metabolic processGO:0010565270.043
regulation of intracellular signal transductionGO:19025312180.042
Rat
regulation of cellular amino acid metabolic processGO:000652120.042
cellular amino acid metabolic processGO:00065201070.042
regulation of molecular functionGO:00650093980.042
Rat
regulation of cellular protein metabolic processGO:00322682670.041
cellular response to oxygen containing compoundGO:19017013860.040
oxoacid metabolic processGO:00434362900.039
regulation of cellular amine metabolic processGO:003323880.039
regulation of phosphorus metabolic processGO:00511743490.038
Rat
regulation of cell proliferationGO:00421273590.037
carboxylic acid metabolic processGO:00197522890.037
transcription from rna polymerase ii promoterGO:00063662520.037
cellular component biogenesisGO:00440853680.036
Rat
positive regulation of cell proliferationGO:00082842490.036
rna metabolic processGO:00160704060.036
regulation of cell differentiationGO:00455953200.036
cellular amine metabolic processGO:0044106380.034
cellular ketone metabolic processGO:0042180510.034
programmed cell deathGO:00125013920.034
brain developmentGO:00074202470.034
positive regulation of signal transductionGO:00099671750.033
reproductive processGO:00224143720.033
regulation of nervous system developmentGO:00519602640.031
positive regulation of nitrogen compound metabolic processGO:00511733340.031
Rat
amine metabolic processGO:0009308380.031
response to inorganic substanceGO:00100353770.030
regulation of catalytic activityGO:00507903040.030
Rat
cellular response to endogenous stimulusGO:00714953770.030
regulation of protein phosphorylationGO:00019321830.030
positive regulation of molecular functionGO:00440932300.029
Rat
positive regulation of response to stimulusGO:00485842850.029
cellular response to hormone stimulusGO:00328702470.029
negative regulation of nitrogen compound metabolic processGO:00511721610.029
negative regulation of gene expressionGO:00106291990.029
circulatory system processGO:00030131830.029
mapk cascadeGO:00001651400.028
single organism biosynthetic processGO:00447113420.028
positive regulation of protein modification processGO:00314011420.028
response to oxygen levelsGO:00704822650.028
regulation of rna biosynthetic processGO:20011413810.028
response to hypoxiaGO:00016662310.027
regulation of neurogenesisGO:00507672470.027
multi organism reproductive processGO:00447032620.027
homeostatic processGO:00425923310.027
catabolic processGO:00090563510.027
Rat
negative regulation of programmed cell deathGO:00430691830.027
regenerationGO:00310991630.027
positive regulation of transcription dna templatedGO:00458931970.027
positive regulation of cell developmentGO:00107201760.026
regulation of neuron differentiationGO:00456642080.026
positive regulation of cellular protein metabolic processGO:00322701670.026
positive regulation of cellular biosynthetic processGO:00313282950.026
positive regulation of multicellular organismal processGO:00512403870.026
single organism reproductive processGO:00447022970.026
response to nutrient levelsGO:00316673700.026
negative regulation of cell communicationGO:00106481580.026
negative regulation of biosynthetic processGO:00098901680.025
regulation of apoptotic processGO:00429813350.025
response to peptide hormoneGO:00434342780.025
macromolecular complex subunit organizationGO:00439333390.025
Rat
positive regulation of biosynthetic processGO:00098913190.025
regulation of multicellular organismal developmentGO:20000263760.025
protein complex subunit organizationGO:00718223020.025
Rat
response to decreased oxygen levelsGO:00362932370.024
positive regulation of phosphorylationGO:00423271770.024
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.024
single organism intracellular transportGO:19025821660.024
peptidyl amino acid modificationGO:00181931260.024
cellular catabolic processGO:00442482950.024
Rat
positive regulation of signalingGO:00230562700.023
transmembrane transportGO:00550854120.023
protein complex biogenesisGO:00702712630.023
protein oligomerizationGO:00512591910.023
chemical homeostasisGO:00488782920.023
locomotionGO:00400112370.023
cellular response to nitrogen compoundGO:19016992100.023
negative regulation of nucleobase containing compound metabolic processGO:00459341530.023
positive regulation of macromolecule biosynthetic processGO:00105572470.023
regulation of system processGO:00440572080.023
cellular chemical homeostasisGO:00550822470.023
regulation of cell projection organizationGO:00313441750.023
multi multicellular organism processGO:00447061380.022
positive regulation of cellular amino acid metabolic processGO:004576410.022
organelle organizationGO:00069962660.022
Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353190.022
Rat
regulation of kinase activityGO:00435491170.022
protein complex assemblyGO:00064612630.022
multicellular organismal reproductive processGO:00486092330.022
positive regulation of cellular amine metabolic processGO:003324030.022
anatomical structure morphogenesisGO:00096532980.022
regulation of canonical wnt signaling pathwayGO:006082840.022
organophosphate metabolic processGO:00196373700.022
Rat
positive regulation of cell differentiationGO:00455972170.021
head developmentGO:00603222470.021
positive regulation of catalytic activityGO:00430851840.021
Rat
nitrogen compound transportGO:00717052290.021
neuron differentiationGO:00301823680.021
cation homeostasisGO:00550801950.021
neuron projection developmentGO:00311752730.021
response to extracellular stimulusGO:00099913800.021
multicellular organism reproductionGO:00325042330.021
regulation of cell developmentGO:00602842630.021
ion transmembrane transportGO:00342203650.021
secretionGO:00469033070.021
negative regulation of cellular protein metabolic processGO:00322691060.021
central nervous system developmentGO:00074173110.021
cellular response to lipidGO:00713962010.021
anion transportGO:00068201780.020
cation transportGO:00068123820.020
cell projection organizationGO:00300303020.020
cellular homeostasisGO:00197252520.020
positive regulation of phosphate metabolic processGO:00459372620.020
Rat
positive regulation of developmental processGO:00510942830.020
cell adhesionGO:00071551100.020
response to estrogenGO:00436272320.020
positive regulation of phosphorus metabolic processGO:00105622620.020
Rat
intracellular transportGO:00469071850.020
negative regulation of cell deathGO:00605482290.020
response to vitaminGO:00332731310.020
response to peptideGO:19016522920.020
cellular response to organic cyclic compoundGO:00714072020.020
positive regulation of gene expressionGO:00106282440.020
cellular cation homeostasisGO:00300031800.019
ion homeostasisGO:00508012120.019
negative regulation of transcription dna templatedGO:00458921160.019
signal transduction by phosphorylationGO:00230141440.019
cellular component morphogenesisGO:00329891550.019
regulation of protein kinase activityGO:00458591050.019
localization of cellGO:00516742020.019
response to cytokineGO:00340972150.019
response to nutrientGO:00075842480.019
negative regulation of apoptotic processGO:00430661810.019
positive regulation of cellular component organizationGO:00511302000.019
Rat
peptidyl tyrosine phosphorylationGO:0018108720.019
negative regulation of cellular biosynthetic processGO:00313271610.019
positive regulation of protein phosphorylationGO:00019341350.019
cellular response to peptideGO:19016531330.019
macromolecular complex assemblyGO:00650032730.018
positive regulation of neurogenesisGO:00507691650.018
positive regulation of programmed cell deathGO:00430681570.018
necroptotic processGO:007026620.018
tissue developmentGO:00098882520.018
positive regulation of cell deathGO:00109421840.018
positive regulation of protein metabolic processGO:00512471780.018
enzyme linked receptor protein signaling pathwayGO:00071671160.018
negative regulation of signalingGO:00230571570.018
immune system processGO:00023762040.018
cellular component movementGO:00069282480.018
regulation of transcription from rna polymerase ii promoterGO:00063572340.018
response to ketoneGO:19016541820.018
response to growth factorGO:00708481890.017
vesicle mediated transportGO:00161921810.017
positive regulation of rna biosynthetic processGO:19026801970.017
response to metal ionGO:00100382530.017
regulation of transferase activityGO:00513381230.017
reproductionGO:00000032450.017
regulation of cellular localizationGO:00603412630.017
protein localizationGO:00081041910.017
blood circulationGO:00080151830.017
negative regulation of nucleic acid templated transcriptionGO:19035071170.017
regulation of neuron projection developmentGO:00109751610.017
cellular response to stressGO:00335542690.017
wound healingGO:00420601220.017
action potentialGO:0001508540.017
response to bacteriumGO:00096172000.017
negative regulation of molecular functionGO:00440921330.017
small gtpase mediated signal transductionGO:0007264360.017
cell motilityGO:00488702020.017
cellular metal ion homeostasisGO:00068751720.016
negative regulation of macromolecule biosynthetic processGO:00105581480.016
negative regulation of multicellular organismal processGO:00512412030.016
proteolysisGO:00065081750.016
neuron developmentGO:00486662860.016
response to woundingGO:00096112540.016
response to carbohydrateGO:00097431830.016
cellular response to organonitrogen compoundGO:00714171970.016
regulation of neuron deathGO:19012141150.016
carbohydrate derivative metabolic processGO:19011353460.016
Rat
calcium ion homeostasisGO:00550741620.016
growthGO:00400071650.016
programmed necrotic cell deathGO:009730020.016
regulation of map kinase activityGO:0043405530.016
reproductive system developmentGO:00614581280.016
response to reactive oxygen speciesGO:00003021200.016
positive regulation of nervous system developmentGO:00519621780.016
cellular ion homeostasisGO:00068731840.016
liver developmentGO:0001889900.016
cell migrationGO:00164771970.016
response to oxidative stressGO:00069791860.016
macromolecule localizationGO:00330362520.016
cellular response to external stimulusGO:00714961180.016
muscle cell proliferationGO:0033002840.015
single organism organelle organizationGO:19025891800.015
Rat
positive regulation of rna metabolic processGO:00512542030.015
metal ion homeostasisGO:00550651860.015
organic substance catabolic processGO:19015753160.015
Rat
response to estradiolGO:00323551640.015
negative regulation of phosphorus metabolic processGO:0010563800.015
nucleotide metabolic processGO:00091172790.015
Rat
cellular protein localizationGO:00346131220.015
peptidyl tyrosine modificationGO:0018212720.015
lipid metabolic processGO:00066292830.015
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.015
organic anion transportGO:00157111320.015
cell type specific apoptotic processGO:00972851340.015
positive regulation of transportGO:00510502450.015
female pregnancyGO:00075651220.015
neurological system processGO:00508772190.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.015
cellular calcium ion homeostasisGO:00068741600.015
negative regulation of protein metabolic processGO:00512481140.015
mesoderm developmentGO:000749820.014
response to acid chemicalGO:00011012220.014
agingGO:00075682410.014
rhythmic processGO:00485111560.014
g protein coupled receptor signaling pathwayGO:00071862420.014
response to corticosteroidGO:00319602350.014
behaviorGO:00076102050.014
regulation of anatomical structure sizeGO:00900661350.014
developmental process involved in reproductionGO:00030061590.014
positive regulation of intracellular signal transductionGO:19025331380.014
immune effector processGO:0002252530.014
cellular response to peptide hormone stimulusGO:00713751200.014
regulation of smooth muscle cell proliferationGO:0048660750.014
response to glucocorticoidGO:00513842230.014
nucleobase containing small molecule metabolic processGO:00550863160.014
Rat
metal ion transportGO:00300012890.013
regulation of immune system processGO:00026821230.013
multicellular organismal signalingGO:0035637440.013
protein heterooligomerizationGO:0051291890.013
divalent inorganic cation homeostasisGO:00725071650.013
regulation of protein serine threonine kinase activityGO:0071900640.013
reactive nitrogen species metabolic processGO:200105710.013
regulation of blood circulationGO:19035221100.013
purine containing compound metabolic processGO:00725212530.013
Rat
regulation of membrane potentialGO:00423911100.013
chromosome segregationGO:000705920.013
regulation of cytokine productionGO:0001817560.013
nucleoside phosphate metabolic processGO:00067532830.013
Rat
positive regulation of mapk cascadeGO:0043410920.013
axis specificationGO:000979840.013
hepaticobiliary system developmentGO:0061008900.013
gamete generationGO:00072761240.013
sexual reproductionGO:00199531480.013
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
negative regulation of transportGO:00510511360.013
single organism behaviorGO:00447081300.013
cytokine productionGO:0001816610.013
negative regulation of signal transductionGO:0009968830.013
anterior posterior pattern specificationGO:000995210.013
ras protein signal transductionGO:0007265290.013
cell cell signalingGO:00072673350.012
cellular response to acid chemicalGO:0071229750.012
negative regulation of catalytic activityGO:00430861030.012
eye morphogenesisGO:004859240.012
cellular divalent inorganic cation homeostasisGO:00725031620.012
cellular response to growth factor stimulusGO:00713631620.012
positive regulation of protein serine threonine kinase activityGO:0071902520.012
cofactor metabolic processGO:0051186950.012
single organism cellular localizationGO:19025801020.012
neuronal action potentialGO:0019228350.012
negative regulation of rna biosynthetic processGO:19026791180.012
negative regulation of canonical wnt signaling pathwayGO:009009040.012
regulation of hydrolase activityGO:00513361430.012
Rat
synaptic transmissionGO:00072682350.012
regulation of proteasomal protein catabolic processGO:006113640.012
negative regulation of rna metabolic processGO:00512531230.012
organ regenerationGO:00311001010.012
organic hydroxy compound metabolic processGO:19016151150.012
organophosphate biosynthetic processGO:00904071430.012
cellular response to steroid hormone stimulusGO:0071383930.012
inorganic ion transmembrane transportGO:00986602290.012
cytoplasmic transportGO:00164821150.012
positive regulation of transferase activityGO:0051347810.011
carbohydrate homeostasisGO:0033500750.011
urogenital system developmentGO:0001655780.011
regulation of hormone levelsGO:00108171870.011
response to alkaloidGO:00432791320.011
cardiac chamber developmentGO:000320510.011
negative regulation of response to stimulusGO:00485851550.011
response to toxic substanceGO:00096361330.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.011
regulation of dendrite developmentGO:0050773590.011
cytosolic calcium ion homeostasisGO:00514801400.011
sequestering of calcium ionGO:005120880.011
positive regulation of protein kinase activityGO:0045860730.011
negative regulation of developmental processGO:00510931250.011
renal system developmentGO:0072001670.011
regulation of locomotionGO:00400121480.011
protein homooligomerizationGO:0051260910.011
defense responseGO:00069521940.011
transmission of nerve impulseGO:0019226420.011
embryonic pattern specificationGO:000988010.011
organic cyclic compound catabolic processGO:19013611750.011
Rat
cellular macromolecule localizationGO:00707271220.011
hematopoietic progenitor cell differentiationGO:000224420.011
actin filament based processGO:0030029860.011
Rat
cardiac muscle cell contractionGO:0086003100.011
response to radiationGO:00093141370.011
sex differentiationGO:00075481130.011
negative regulation of phosphate metabolic processGO:0045936800.011
forebrain developmentGO:0030900980.011
regulation of tube sizeGO:0035150890.011
purine nucleotide metabolic processGO:00061632290.011
Rat
secretion by cellGO:00329402480.011
response to molecule of bacterial originGO:00022371940.011
regulation of mapk cascadeGO:00434081160.011
smooth muscle cell proliferationGO:0048659770.011
biological adhesionGO:00226101100.011
sequestering of metal ionGO:005123890.011
male gamete generationGO:0048232990.011
positive regulation of kinase activityGO:0033674770.011
regulation of cell motilityGO:20001451310.010
multicellular organism growthGO:003526410.010
cellular response to metal ionGO:0071248550.010
positive regulation of map kinase activityGO:0043406460.010
cell part morphogenesisGO:00329901230.010
amide transportGO:00428861050.010
leukocyte activationGO:0045321760.010
regulation of blood vessel sizeGO:0050880890.010
regulation of stem cell differentiationGO:200073620.010
regulation of cell migrationGO:00303341280.010
spermatogenesisGO:0007283990.010
cell projection morphogenesisGO:00488581230.010
response to ethanolGO:00454711620.010
negative regulation of cell differentiationGO:0045596990.010
circulatory system developmentGO:00723591340.010
oxidation reduction processGO:00551143040.010
organonitrogen compound biosynthetic processGO:19015661670.010
positive regulation of cell projection organizationGO:00313461110.010
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.010
cellular response to mechanical stimulusGO:0071260480.010
cation transmembrane transportGO:00986552630.010
dephosphorylationGO:0016311980.010
regulation of neuron apoptotic processGO:0043523830.010

Arhgef5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.019
disease of anatomical entityDOID:700.019
disease of metabolismDOID:001466700.019
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
cardiovascular system diseaseDOID:128700.015
musculoskeletal system diseaseDOID:1700.014
organ system cancerDOID:005068600.013
muscular diseaseDOID:008000000.012
central nervous system diseaseDOID:33100.011
inherited metabolic disorderDOID:65500.011
sensory system diseaseDOID:005015500.011