Rattus norvegicus

13 known processes

Arhgef1

Rho guanine nucleotide exchange factor (GEF) 1

(Aliases: MGC108950,Lsc)

Arhgef1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of mrna splicing via spliceosomeGO:004802430.234
macromolecular complex subunit organizationGO:00439333390.128
g protein coupled receptor signaling pathwayGO:00071862420.112
negative regulation of cell cycle g1 s phase transitionGO:190280720.111
neuron projection developmentGO:00311752730.110
response to metal ionGO:00100382530.097
negative regulation of transcription dna templatedGO:00458921160.095
regulation of molecular functionGO:00650093980.094
protein phosphorylationGO:00064683450.092
transcription dna templatedGO:00063513770.088
regulation of cell cycle g1 s phase transitionGO:190280670.088
regulation of cellular localizationGO:00603412630.081
positive regulation of biosynthetic processGO:00098913190.080
purine containing compound metabolic processGO:00725212530.080
negative regulation of nitrogen compound metabolic processGO:00511721610.079
purine ribonucleoside catabolic processGO:00461301240.069
organelle organizationGO:00069962660.069
regulation of nucleic acid templated transcriptionGO:19035063800.068
cellular homeostasisGO:00197252520.066
positive regulation of rna metabolic processGO:00512542030.063
regulation of rna metabolic processGO:00512523910.063
positive regulation of transportGO:00510502450.061
homeostatic processGO:00425923310.060
regulation of intracellular signal transductionGO:19025312180.059
protein complex biogenesisGO:00702712630.059
regulation of signal transductionGO:00099663180.058
negative regulation of cellular metabolic processGO:00313242810.056
positive regulation of nitrogen compound metabolic processGO:00511733340.055
intracellular signal transductionGO:00355563140.054
response to other organismGO:00517072200.054
regulation of multicellular organismal developmentGO:20000263760.052
cell cycleGO:00070491010.051
neuron differentiationGO:00301823680.051
organophosphate catabolic processGO:00464341480.050
positive regulation of gene expressionGO:00106282440.050
macromolecule localizationGO:00330362520.049
cellular component assemblyGO:00226073600.049
nucleobase containing small molecule metabolic processGO:00550863160.046
regulation of cell cycleGO:0051726730.044
cell cycle g1 s phase transitionGO:0044843130.044
cytoskeleton organizationGO:00070101110.041
macromolecular complex assemblyGO:00650032730.041
nucleotide catabolic processGO:00091661390.041
positive regulation of cell communicationGO:00106472710.040
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.039
cellular chemical homeostasisGO:00550822470.039
cellular component biogenesisGO:00440853680.038
positive regulation of secretionGO:00510471400.038
regulation of phosphate metabolic processGO:00192203490.037
negative regulation of signalingGO:00230571570.037
positive regulation of nucleobase containing compound metabolic processGO:00459353190.037
nucleoside metabolic processGO:00091161790.036
chromatin assembly or disassemblyGO:000633310.036
ribonucleotide metabolic processGO:00092592310.036
regulation of protein phosphorylationGO:00019321830.035
purine ribonucleotide metabolic processGO:00091502270.035
brain developmentGO:00074202470.035
negative regulation of transportGO:00510511360.035
regulation of cell proliferationGO:00421273590.035
response to biotic stimulusGO:00096072260.035
response to temperature stimulusGO:0009266940.035
regulation of rna biosynthetic processGO:20011413810.035
cellular response to endogenous stimulusGO:00714953770.035
regulation of protein kinase activityGO:00458591050.034
negative regulation of rna metabolic processGO:00512531230.034
regulation of protein localizationGO:0032880810.034
regulation of alternative mrna splicing via spliceosomeGO:000038120.034
atp catabolic processGO:0006200540.034
central nervous system developmentGO:00074173110.034
response to external biotic stimulusGO:00432072210.033
peptidyl amino acid modificationGO:00181931260.033
purine nucleoside monophosphate catabolic processGO:0009128550.033
positive regulation of phosphate metabolic processGO:00459372620.033
carbohydrate derivative catabolic processGO:19011361470.033
regulation of cellular component organizationGO:00511283680.033
immune system processGO:00023762040.032
reproductionGO:00000032450.032
Worm
regulation of catalytic activityGO:00507903040.032
response to radiationGO:00093141370.032
cellular component movementGO:00069282480.032
negative regulation of cellular biosynthetic processGO:00313271610.031
single organism organelle organizationGO:19025891800.031
activation of mapkkk activityGO:000018510.031
negative regulation of cell communicationGO:00106481580.030
protein complex assemblyGO:00064612630.030
secretion by cellGO:00329402480.030
purine nucleotide metabolic processGO:00061632290.030
response to peptideGO:19016522920.030
single organism reproductive processGO:00447022970.029
ribonucleoside triphosphate metabolic processGO:00091991410.029
negative regulation of nucleic acid templated transcriptionGO:19035071170.029
response to woundingGO:00096112540.028
organophosphate metabolic processGO:00196373700.028
negative regulation of macromolecule metabolic processGO:00106052600.028
positive regulation of nucleic acid templated transcriptionGO:19035081970.028
regulation of homeostatic processGO:00328441010.028
tube formationGO:003514830.028
response to inorganic substanceGO:00100353770.027
response to oxidative stressGO:00069791860.027
purine nucleotide catabolic processGO:00061951360.027
cell cycle checkpointGO:000007520.027
negative regulation of cell cycle phase transitionGO:190198840.027
glutamate receptor signaling pathwayGO:0007215430.027
cytosolic calcium ion homeostasisGO:00514801400.027
negative regulation of macromolecule biosynthetic processGO:00105581480.027
cellular response to stressGO:00335542690.026
protein oligomerizationGO:00512591910.026
purine containing compound catabolic processGO:00725231380.026
carbohydrate derivative metabolic processGO:19011353460.026
regulation of phosphorylationGO:00423252480.026
mitotic cell cycleGO:0000278490.026
regulation of cell developmentGO:00602842630.026
purine ribonucleoside triphosphate metabolic processGO:00092051400.026
positive regulation of intracellular signal transductionGO:19025331380.026
positive regulation of transcription dna templatedGO:00458931970.026
cellular response to organonitrogen compoundGO:00714171970.026
regulation of phosphorus metabolic processGO:00511743490.025
sensory perceptionGO:00076001010.025
Worm
negative regulation of biosynthetic processGO:00098901680.024
vasculogenesisGO:000157030.024
metal ion homeostasisGO:00550651860.024
regulation of neurogenesisGO:00507672470.024
calcium ion homeostasisGO:00550741620.024
ribonucleoside triphosphate catabolic processGO:00092031220.024
negative regulation of rna biosynthetic processGO:19026791180.024
endocytosisGO:0006897840.024
peptide biosynthetic processGO:004304330.023
response to cytokineGO:00340972150.023
regulation of nervous system developmentGO:00519602640.023
cytoplasmic transportGO:00164821150.023
ras protein signal transductionGO:0007265290.023
spindle organizationGO:000705120.023
regulation of cell differentiationGO:00455953200.022
small gtpase mediated signal transductionGO:0007264360.022
secretionGO:00469033070.022
cell projection organizationGO:00300303020.022
rna metabolic processGO:00160704060.022
response to transforming growth factor betaGO:0071559460.022
regulation of receptor recyclingGO:000191960.022
positive regulation of protein phosphorylationGO:00019341350.022
positive regulation of molecular functionGO:00440932300.021
calcium ion transportGO:00068161310.021
nucleotide metabolic processGO:00091172790.021
nucleocytoplasmic transportGO:0006913480.021
mapk cascadeGO:00001651400.021
mitotic cell cycle processGO:1903047350.021
neurological system processGO:00508772190.021
Worm
purine ribonucleoside metabolic processGO:00461281680.021
regulation of locomotionGO:00400121480.021
negative regulation of protein metabolic processGO:00512481140.021
ribonucleotide catabolic processGO:00092611360.021
rna biosynthetic processGO:00327743800.020
protein localizationGO:00081041910.020
amine metabolic processGO:0009308380.020
vesicle mediated transportGO:00161921810.020
regulation of transcription from rna polymerase ii promoterGO:00063572340.020
positive regulation of cellular biosynthetic processGO:00313282950.020
multicellular organismal reproductive processGO:00486092330.020
Worm
positive regulation of signalingGO:00230562700.020
cellular cation homeostasisGO:00300031800.019
defense responseGO:00069521940.019
locomotionGO:00400112370.019
Worm
nucleoside phosphate metabolic processGO:00067532830.019
multicellular organism reproductionGO:00325042330.019
Worm
divalent inorganic cation homeostasisGO:00725071650.019
cellular metal ion homeostasisGO:00068751720.019
tissue developmentGO:00098882520.019
chemical homeostasisGO:00488782920.019
response to lipopolysaccharideGO:00324961910.019
cellular calcium ion homeostasisGO:00068741600.018
response to ammonium ionGO:0060359710.018
positive regulation of cytosolic calcium ion concentrationGO:00072041220.018
nucleobase containing compound catabolic processGO:00346551520.018
ribose phosphate metabolic processGO:00196932350.018
protein complex subunit organizationGO:00718223020.018
cellular divalent inorganic cation homeostasisGO:00725031620.018
negative regulation of metabolic processGO:00098923310.018
ion homeostasisGO:00508012120.017
cation homeostasisGO:00550801950.017
apoptotic processGO:00069153810.017
reproductive processGO:00224143720.017
Worm
embryo developmentGO:0009790490.017
Worm
multi organism reproductive processGO:00447032620.017
Worm
cellular ion homeostasisGO:00068731840.017
neuron developmentGO:00486662860.017
negative regulation of response to stimulusGO:00485851550.017
atp metabolic processGO:0046034720.017
cellular response to nitrogen compoundGO:19016992100.017
negative regulation of mitotic cell cycle phase transitionGO:190199130.017
ribonucleoside metabolic processGO:00091191740.017
cellular response to peptideGO:19016531330.017
programmed cell deathGO:00125013920.017
positive regulation of apoptotic processGO:00430651540.017
response to hydrogen peroxideGO:0042542890.016
regulation of neuron differentiationGO:00456642080.016
nucleoside triphosphate catabolic processGO:00091431230.016
heterocycle catabolic processGO:00467001670.016
positive regulation of rna biosynthetic processGO:19026801970.016
negative regulation of gene expressionGO:00106291990.016
dna metabolic processGO:0006259960.016
cellular amine metabolic processGO:0044106380.016
defense response to gram negative bacteriumGO:005082930.016
signal transduction by phosphorylationGO:00230141440.016
positive regulation of cell deathGO:00109421840.016
ribonucleoside catabolic processGO:00424541260.016
regulation of cellular protein metabolic processGO:00322682670.015
regulation of purine nucleotide metabolic processGO:19005421150.015
catabolic processGO:00090563510.015
ion transmembrane transportGO:00342203650.015
regulation of secretionGO:00510462240.015
asymmetric protein localizationGO:000810520.015
glycosyl compound metabolic processGO:19016571820.015
regulation of cell projection organizationGO:00313441750.015
regulation of transcription dna templatedGO:00063553740.015
mammary gland epithelium developmentGO:006118010.015
inflammatory responseGO:00069541500.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
ribonucleoside monophosphate metabolic processGO:0009161880.015
cellular protein localizationGO:00346131220.015
lipid metabolic processGO:00066292830.015
cellular response to growth factor stimulusGO:00713631620.015
heart morphogenesisGO:000300730.014
actin filament organizationGO:0007015420.014
purine ribonucleoside triphosphate catabolic processGO:00092071220.014
organonitrogen compound catabolic processGO:19015651790.014
response to estrogenGO:00436272320.014
cellular macromolecule localizationGO:00707271220.014
actin filament based processGO:0030029860.014
negative regulation of phosphorylationGO:0042326570.014
regulation of response to stressGO:00801341260.014
carboxylic acid metabolic processGO:00197522890.014
regulation of nucleotide metabolic processGO:00061401170.014
hematopoietic or lymphoid organ developmentGO:0048534360.014
aromatic compound catabolic processGO:00194391680.014
regulation of growthGO:00400081050.014
nucleoside triphosphate metabolic processGO:00091411440.013
dna integrity checkpointGO:003157020.013
regulation of anatomical structure morphogenesisGO:00226031410.013
transmembrane transportGO:00550854120.013
head developmentGO:00603222470.013
single organism intracellular transportGO:19025821660.013
lipid transportGO:0006869610.013
positive regulation of cell developmentGO:00107201760.013
purine ribonucleoside monophosphate metabolic processGO:0009167840.013
regulation of small gtpase mediated signal transductionGO:0051056480.013
sensory organ developmentGO:0007423740.013
purine ribonucleoside monophosphate catabolic processGO:0009169550.013
positive regulation of cellular protein metabolic processGO:00322701670.013
forebrain developmentGO:0030900980.013
positive regulation of macromolecule biosynthetic processGO:00105572470.013
regulation of neuron projection developmentGO:00109751610.013
positive regulation of programmed cell deathGO:00430681570.013
negative regulation of cell developmentGO:0010721820.013
positive regulation of cellular component organizationGO:00511302000.013
carbohydrate derivative biosynthetic processGO:19011371240.013
mitotic spindle organizationGO:000705220.013
positive regulation of cell proliferationGO:00082842490.012
response to light stimulusGO:0009416520.012
response to carbohydrateGO:00097431830.012
response to bacteriumGO:00096172000.012
cellular nitrogen compound catabolic processGO:00442701630.012
heart developmentGO:0007507720.012
regulation of protein serine threonine kinase activityGO:0071900640.012
regulation of ion transportGO:00432692450.012
organic cyclic compound catabolic processGO:19013611750.012
nucleoside monophosphate catabolic processGO:0009125560.012
cell morphogenesisGO:00009021420.012
rna splicing via transesterification reactionsGO:000037570.012
agingGO:00075682410.012
organonitrogen compound biosynthetic processGO:19015661670.012
nucleoside catabolic processGO:00091641260.012
divalent metal ion transportGO:00708381320.012
regulation of the force of heart contraction by chemical signalGO:000305720.012
histone modificationGO:0016570300.012
negative regulation of protein phosphorylationGO:0001933440.012
negative regulation of cell differentiationGO:0045596990.012
transcription from rna polymerase ii promoterGO:00063662520.012
anatomical structure morphogenesisGO:00096532980.011
nucleic acid templated transcriptionGO:00976593790.011
positive regulation of response to stimulusGO:00485842850.011
cellular response to peptide hormone stimulusGO:00713751200.011
innate immune responseGO:0045087350.011
positive regulation of protein metabolic processGO:00512471780.011
regulation of membrane potentialGO:00423911100.011
positive regulation of kinase activityGO:0033674770.011
female pregnancyGO:00075651220.011
regulation of immune responseGO:0050776550.011
muscle system processGO:00030121150.011
organic substance catabolic processGO:19015753160.011
positive regulation of secretion by cellGO:19035321280.011
regulation of cell cycle processGO:0010564310.011
positive regulation of hydrolase activityGO:0051345860.011
positive regulation of nervous system developmentGO:00519621780.011
response to acid chemicalGO:00011012220.011
regulation of cell motilityGO:20001451310.011
receptor metabolic processGO:0043112180.011
reactive oxygen species biosynthetic processGO:190340980.011
cell motilityGO:00488702020.011
negative regulation of catalytic activityGO:00430861030.011
cellular response to hormone stimulusGO:00328702470.011
regulation of transferase activityGO:00513381230.011
purine ribonucleotide catabolic processGO:00091541360.010
axis specificationGO:000979840.010
response to campGO:0051591910.010
regulation of embryonic developmentGO:004599520.010
cellular response to abiotic stimulusGO:0071214850.010
positive regulation of mapk cascadeGO:0043410920.010
negative regulation of neuron differentiationGO:0045665620.010
regulation of cellular component biogenesisGO:0044087860.010
ribonucleoside monophosphate catabolic processGO:0009158550.010
response to potassium ionGO:003586490.010
negative regulation of multicellular organismal processGO:00512412030.010
single organism behaviorGO:00447081300.010
Worm
liver developmentGO:0001889900.010
regulation of cellular ketone metabolic processGO:0010565270.010
regulation of establishment of protein localizationGO:0070201690.010

Arhgef1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.020
disease of anatomical entityDOID:700.020
nervous system diseaseDOID:86300.011