Rattus norvegicus

56 known processes

Traf6

Tnf receptor-associated factor 6

Traf6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna metabolic processGO:00160704060.132
Human Zebrafish Mouse
regulation of nucleic acid templated transcriptionGO:19035063800.090
Human Zebrafish Mouse
nucleic acid templated transcriptionGO:00976593790.082
Human Zebrafish Mouse
protein phosphorylationGO:00064683450.077
Human
regulation of rna metabolic processGO:00512523910.068
Human Zebrafish Mouse
negative regulation of cell deathGO:00605482290.067
catabolic processGO:00090563510.064
transcription dna templatedGO:00063513770.064
Human Zebrafish Mouse
regulation of phosphate metabolic processGO:00192203490.062
Human
regulation of rna biosynthetic processGO:20011413810.061
Human Zebrafish Mouse
negative regulation of programmed cell deathGO:00430691830.057
regulation of cellular protein metabolic processGO:00322682670.056
Human
positive regulation of gene expressionGO:00106282440.052
Human Zebrafish
rna biosynthetic processGO:00327743800.049
Human Zebrafish Mouse
regulation of intracellular signal transductionGO:19025312180.048
Human Mouse
cellular amino acid metabolic processGO:00065201070.048
negative regulation of gene expressionGO:00106291990.048
Human
neuron deathGO:00709971270.047
regulation of cell proliferationGO:00421273590.047
negative regulation of macromolecule metabolic processGO:00106052600.047
Human
regulation of protein metabolic processGO:00512462890.046
Human Mouse
carboxylic acid metabolic processGO:00197522890.046
regulation of programmed cell deathGO:00430673410.045
cell migrationGO:00164771970.045
regulation of signal transductionGO:00099663180.045
Human Mouse
metal ion transportGO:00300012890.044
carbohydrate derivative metabolic processGO:19011353460.042
positive regulation of transportGO:00510502450.041
nucleobase containing small molecule metabolic processGO:00550863160.040
cellular catabolic processGO:00442482950.040
macromolecular complex subunit organizationGO:00439333390.040
positive regulation of phosphate metabolic processGO:00459372620.039
Human
regulation of phosphorus metabolic processGO:00511743490.039
Human
positive regulation of cellular protein metabolic processGO:00322701670.039
Human
apoptotic processGO:00069153810.038
positive regulation of protein modification processGO:00314011420.038
Human
neuron differentiationGO:00301823680.038
positive regulation of nucleobase containing compound metabolic processGO:00459353190.037
Human Zebrafish
negative regulation of cellular metabolic processGO:00313242810.037
Human
regulation of transcription dna templatedGO:00063553740.036
Human Zebrafish Mouse
positive regulation of phosphorylationGO:00423271770.036
Human
regulation of cellular amine metabolic processGO:003323880.034
response to extracellular stimulusGO:00099913800.034
programmed cell deathGO:00125013920.034
cation transportGO:00068123820.034
cellular amine metabolic processGO:0044106380.033
positive regulation of cell proliferationGO:00082842490.033
peptidyl amino acid modificationGO:00181931260.032
amine metabolic processGO:0009308380.032
negative regulation of apoptotic processGO:00430661810.031
secretionGO:00469033070.031
Mouse
organic acid metabolic processGO:00060822920.031
macromolecular complex assemblyGO:00650032730.031
organic substance catabolic processGO:19015753160.031
regulation of transcription from rna polymerase ii promoterGO:00063572340.030
Human
response to nutrient levelsGO:00316673700.030
transcription from rna polymerase ii promoterGO:00063662520.030
Human
regulation of cellular ketone metabolic processGO:0010565270.030
cell projection organizationGO:00300303020.029
regulation of cellular catabolic processGO:00313291010.029
neuron developmentGO:00486662860.029
regulation of catabolic processGO:00098941130.029
cellular ketone metabolic processGO:0042180510.029
protein autophosphorylationGO:0046777660.028
regulation of cellular amino acid metabolic processGO:000652120.028
intracellular signal transductionGO:00355563140.028
regulation of phosphorylationGO:00423252480.028
Human
positive regulation of protein metabolic processGO:00512471780.027
Human Mouse
agingGO:00075682410.027
cell morphogenesis involved in differentiationGO:00009041190.027
positive regulation of cellular amino acid metabolic processGO:004576410.026
positive regulation of signalingGO:00230562700.026
Human Mouse
central nervous system developmentGO:00074173110.026
oxoacid metabolic processGO:00434362900.026
regulation of protein modification processGO:00313991940.026
Human
positive regulation of cellular amine metabolic processGO:003324030.026
response to acid chemicalGO:00011012220.026
nucleoside phosphate metabolic processGO:00067532830.025
positive regulation of cell communicationGO:00106472710.025
Human Mouse
positive regulation of nitrogen compound metabolic processGO:00511733340.025
Human Zebrafish
positive regulation of cell deathGO:00109421840.025
positive regulation of macromolecule biosynthetic processGO:00105572470.025
Human Zebrafish Mouse
cellular response to endogenous stimulusGO:00714953770.025
ribonucleotide metabolic processGO:00092592310.025
negative regulation of metabolic processGO:00098923310.025
Human
response to nutrientGO:00075842480.025
regulation of apoptotic processGO:00429813350.025
single organism catabolic processGO:00447122830.025
cell motilityGO:00488702020.025
small gtpase mediated signal transductionGO:0007264360.025
organophosphate metabolic processGO:00196373700.025
reproductive processGO:00224143720.024
locomotionGO:00400112370.024
negative regulation of biosynthetic processGO:00098901680.024
Human
positive regulation of developmental processGO:00510942830.024
Human
protein heterooligomerizationGO:0051291890.024
positive regulation of phosphorus metabolic processGO:00105622620.024
Human
nucleotide metabolic processGO:00091172790.023
protein transportGO:00150311320.023
Mouse
purine nucleoside metabolic processGO:00422781690.023
cellular response to oxygen containing compoundGO:19017013860.023
Human Mouse
organic cyclic compound catabolic processGO:19013611750.023
positive regulation of molecular functionGO:00440932300.023
Human Mouse
positive regulation of response to stimulusGO:00485842850.023
Human Mouse
cellular response to stressGO:00335542690.023
regulation of neuron deathGO:19012141150.023
ras protein signal transductionGO:0007265290.022
positive regulation of biosynthetic processGO:00098913190.022
Human Zebrafish Mouse
protein localizationGO:00081041910.022
Mouse
single organism reproductive processGO:00447022970.022
protein oligomerizationGO:00512591910.022
regulation of protein phosphorylationGO:00019321830.022
Human
nucleoside metabolic processGO:00091161790.022
cellular nitrogen compound catabolic processGO:00442701630.022
ribonucleoside metabolic processGO:00091191740.022
purine ribonucleotide metabolic processGO:00091502270.022
regulation of mapk cascadeGO:00434081160.021
Human
cell cell signalingGO:00072673350.021
purine nucleotide metabolic processGO:00061632290.021
negative regulation of macromolecule biosynthetic processGO:00105581480.021
Human
cellular response to organonitrogen compoundGO:00714171970.021
neuron projection developmentGO:00311752730.021
localization of cellGO:00516742020.021
regulation of cell differentiationGO:00455953200.021
Human
signal transduction by phosphorylationGO:00230141440.021
regulation of cellular localizationGO:00603412630.021
Mouse
oxidation reduction processGO:00551143040.020
regulation of molecular functionGO:00650093980.020
Human Mouse
muscle system processGO:00030121150.020
cellular response to external stimulusGO:00714961180.020
heterocycle catabolic processGO:00467001670.020
positive regulation of cellular biosynthetic processGO:00313282950.020
Human Zebrafish Mouse
multicellular organism reproductionGO:00325042330.020
regulation of nervous system developmentGO:00519602640.020
cellular response to cytokine stimulusGO:00713451270.019
nucleobase containing compound catabolic processGO:00346551520.019
cellular component biogenesisGO:00440853680.019
regulation of catalytic activityGO:00507903040.019
Human
macroautophagyGO:001623640.019
protein complex subunit organizationGO:00718223020.019
regulation of protein localizationGO:0032880810.019
Mouse
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.019
Human
response to mechanical stimulusGO:00096121340.019
cardiovascular system developmentGO:00723581340.019
response to glucoseGO:00097491360.019
regulation of cell projection organizationGO:00313441750.019
macromolecule catabolic processGO:0009057580.019
negative regulation of rna metabolic processGO:00512531230.019
Human
response to external biotic stimulusGO:00432072210.018
Human Zebrafish Mouse
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
Human Zebrafish
cellular response to organic cyclic compoundGO:00714072020.018
protein complex assemblyGO:00064612630.018
response to growth factorGO:00708481890.018
positive regulation of protein phosphorylationGO:00019341350.018
Human
response to estrogenGO:00436272320.018
negative regulation of nitrogen compound metabolic processGO:00511721610.018
Human
transmembrane transportGO:00550854120.018
positive regulation of catalytic activityGO:00430851840.018
Human
purine containing compound metabolic processGO:00725212530.018
ribonucleoside triphosphate metabolic processGO:00091991410.018
regulation of response to stressGO:00801341260.018
Human
positive regulation of cell differentiationGO:00455972170.018
Human
nitrogen compound transportGO:00717052290.017
regulation of hydrolase activityGO:00513361430.017
regulation of secretionGO:00510462240.017
Mouse
purine ribonucleoside catabolic processGO:00461301240.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.017
Human
anatomical structure morphogenesisGO:00096532980.017
Mouse
single organism organelle organizationGO:19025891800.017
positive regulation of catabolic processGO:0009896780.017
positive regulation of programmed cell deathGO:00430681570.017
ribonucleoside catabolic processGO:00424541260.017
response to carbohydrateGO:00097431830.016
cellular component assemblyGO:00226073600.016
axon developmentGO:0061564960.016
cell morphogenesisGO:00009021420.016
dna metabolic processGO:0006259960.016
proteolysisGO:00065081750.016
blood circulationGO:00080151830.016
response to cytokineGO:00340972150.016
glycosyl compound metabolic processGO:19016571820.016
axis specificationGO:000979840.016
aromatic compound catabolic processGO:00194391680.016
cytoplasmic transportGO:00164821150.016
protein complex biogenesisGO:00702712630.016
cellular response to lipidGO:00713962010.016
Human Mouse
organonitrogen compound biosynthetic processGO:19015661670.016
chemosensory behaviorGO:000763520.016
negative regulation of cellular biosynthetic processGO:00313271610.016
Human
single organism intracellular transportGO:19025821660.015
organonitrogen compound catabolic processGO:19015651790.015
response to inorganic substanceGO:00100353770.015
cellular response to nitrogen compoundGO:19016992100.015
cell projection morphogenesisGO:00488581230.015
ribose phosphate metabolic processGO:00196932350.015
cell type specific apoptotic processGO:00972851340.015
embryonic pattern specificationGO:000988010.015
regulation of cellular component organizationGO:00511283680.015
carbohydrate derivative catabolic processGO:19011361470.015
regulation of cell migrationGO:00303341280.015
response to glucocorticoidGO:00513842230.015
divalent inorganic cation transportGO:00725111340.015
ion transmembrane transportGO:00342203650.015
secretion by cellGO:00329402480.014
Mouse
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
response to hexoseGO:00097461440.014
development of primary sexual characteristicsGO:00451371070.014
multicellular organismal reproductive processGO:00486092330.014
positive regulation of cell developmentGO:00107201760.014
positive regulation of rna metabolic processGO:00512542030.014
Human Zebrafish
reproductive structure developmentGO:00486081280.014
neuron projection morphogenesisGO:00488121220.014
cell morphogenesis involved in neuron differentiationGO:00486671060.014
regulation of cell developmentGO:00602842630.014
positive regulation of signal transductionGO:00099671750.014
Human Mouse
ion homeostasisGO:00508012120.014
positive regulation of cellular catabolic processGO:0031331710.014
response to metal ionGO:00100382530.014
regulation of system processGO:00440572080.014
reactive oxygen species metabolic processGO:0072593370.014
cellular component morphogenesisGO:00329891550.014
organelle organizationGO:00069962660.014
cellular response to growth factor stimulusGO:00713631620.014
regulation of multicellular organismal developmentGO:20000263760.014
Human
anterior posterior pattern specificationGO:000995210.013
b cell differentiationGO:003018320.013
positive regulation of ion transportGO:0043270940.013
positive regulation of transcription dna templatedGO:00458931970.013
Human Zebrafish
regulation of membrane potentialGO:00423911100.013
positive regulation of nervous system developmentGO:00519621780.013
purine ribonucleotide catabolic processGO:00091541360.013
nucleotide catabolic processGO:00091661390.013
multicellular organism growthGO:003526410.013
response to woundingGO:00096112540.013
macromolecule localizationGO:00330362520.013
Mouse
muscle structure developmentGO:0061061870.013
developmental process involved in reproductionGO:00030061590.013
nucleoside phosphate catabolic processGO:19012921400.013
circulatory system developmentGO:00723591340.013
regenerationGO:00310991630.013
taxisGO:0042330670.013
purine ribonucleoside metabolic processGO:00461281680.013
homeostatic processGO:00425923310.013
Mouse
muscle contractionGO:0006936880.013
negative regulation of nucleic acid templated transcriptionGO:19035071170.013
Human
negative regulation of cellular protein metabolic processGO:00322691060.013
cellular response to acid chemicalGO:0071229750.013
enzyme linked receptor protein signaling pathwayGO:00071671160.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
learning or memoryGO:0007611900.013
reactive nitrogen species metabolic processGO:200105710.013
response to radiationGO:00093141370.012
anatomical structure formation involved in morphogenesisGO:0048646830.012
Mouse
immune system processGO:00023762040.012
Human Zebrafish Mouse
regulation of transferase activityGO:00513381230.012
Human
vesicle mediated transportGO:00161921810.012
epithelium developmentGO:0060429960.012
Mouse
monovalent inorganic cation transportGO:00156721720.012
positive regulation of neurogenesisGO:00507691650.012
negative regulation of transportGO:00510511360.012
purine ribonucleoside triphosphate metabolic processGO:00092051400.012
nucleoside catabolic processGO:00091641260.012
regulation of proteasomal protein catabolic processGO:006113640.012
regulation of cellular response to stressGO:0080135490.012
Human
positive regulation of cell projection organizationGO:00313461110.012
mechanoreceptor differentiationGO:004249020.012
intracellular transportGO:00469071850.012
cellular homeostasisGO:00197252520.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
Human
rhythmic processGO:00485111560.012
negative regulation of rna biosynthetic processGO:19026791180.012
Human
negative regulation of molecular functionGO:00440921330.012
cellular response to tumor necrosis factorGO:0071356460.012
response to tumor necrosis factorGO:0034612560.012
neurological system processGO:00508772190.012
purine nucleoside triphosphate catabolic processGO:00091461220.012
biological adhesionGO:00226101100.012
signal releaseGO:00230611450.012
single organism behaviorGO:00447081300.012
negative regulation of catalytic activityGO:00430861030.012
cell part morphogenesisGO:00329901230.012
reactive oxygen species biosynthetic processGO:190340980.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
regulation of reactive oxygen species biosynthetic processGO:190342650.012
response to other organismGO:00517072200.012
Human Zebrafish Mouse
cellular component movementGO:00069282480.011
circulatory system processGO:00030131830.011
positive regulation of mapk cascadeGO:0043410920.011
Human
response to activityGO:0014823730.011
vascular process in circulatory systemGO:0003018960.011
axonogenesisGO:0007409710.011
regulation of growthGO:00400081050.011
vasculature developmentGO:0001944700.011
response to monosaccharideGO:00342841590.011
regulation of canonical wnt signaling pathwayGO:006082840.011
positive regulation of rna biosynthetic processGO:19026801970.011
Human Zebrafish
cellular chemical homeostasisGO:00550822470.011
response to temperature stimulusGO:0009266940.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
regulation of cell morphogenesisGO:0022604770.011
embryonic axis specificationGO:000057810.011
rho protein signal transductionGO:0007266110.011
circadian rhythmGO:0007623880.011
regulation of protein kinase activityGO:00458591050.011
Human
regulation of anatomical structure sizeGO:00900661350.011
regulation of metal ion transportGO:00109591180.011
heart morphogenesisGO:000300730.011
ribonucleotide catabolic processGO:00092611360.011
positive regulation of nucleotide metabolic processGO:0045981910.011
defense responseGO:00069521940.011
Zebrafish
growthGO:00400071650.011
regulation of secretion by cellGO:19035302080.011
Mouse
sodium ion transportGO:0006814820.011
purine containing compound catabolic processGO:00725231380.011
response to alkaloidGO:00432791320.011
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.011
synaptic transmissionGO:00072682350.011
response to lipopolysaccharideGO:00324961910.011
Human Mouse
organophosphate catabolic processGO:00464341480.011
cell adhesionGO:00071551100.011
chromosome segregationGO:000705920.011
anion transportGO:00068201780.011
cellular response to extracellular stimulusGO:0031668730.011
i kappab kinase nf kappab signalingGO:0007249190.010
Human Mouse
cell growthGO:00160491040.010
metal ion homeostasisGO:00550651860.010
blood vessel morphogenesisGO:0048514580.010
positive regulation of multicellular organismal processGO:00512403870.010
Human Mouse
gliogenesisGO:0042063930.010
brain developmentGO:00074202470.010
ribonucleotide biosynthetic processGO:0009260850.010
olfactory behaviorGO:004204820.010
response to toxic substanceGO:00096361330.010
behaviorGO:00076102050.010
regulation of neuron differentiationGO:00456642080.010
regulation of hormone levelsGO:00108171870.010
hormone secretionGO:00468791150.010
gastrulationGO:000736920.010
autonomic nervous system developmentGO:004848330.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.010
response to amino acidGO:0043200750.010
regulation of neurogenesisGO:00507672470.010
head developmentGO:00603222470.010
response to decreased oxygen levelsGO:00362932370.010
carbohydrate derivative biosynthetic processGO:19011371240.010
neuron apoptotic processGO:0051402880.010
chemical homeostasisGO:00488782920.010
sensory perception of painGO:0019233730.010
regulation of cellular component movementGO:00512701500.010

Traf6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
nervous system diseaseDOID:86300.047
central nervous system diseaseDOID:33100.020
musculoskeletal system diseaseDOID:1700.017
bone diseaseDOID:008000100.017
connective tissue diseaseDOID:6500.017
disease of metabolismDOID:001466700.015
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.014
cancerDOID:16200.014