IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Gipc1

GIPC PDZ domain containing family, member 1

(Aliases: Gipc,Rgs19ip1,Rgs19)

Entrez: 83823
RGD: 68338
Ensembl: ENSRNOG00000003864
UniProtKB: Q9Z254

Process Predictions
Disease Predictions

Gipc1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
catabolic process	GO:0009056	351	0.379	Mouse
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.327
purine ribonucleoside metabolic process	GO:0046128	168	0.310
aromatic compound catabolic process	GO:0019439	168	0.287
ribonucleoside catabolic process	GO:0042454	126	0.279
purine nucleoside catabolic process	GO:0006152	124	0.274
nucleoside catabolic process	GO:0009164	126	0.271
nucleoside triphosphate catabolic process	GO:0009143	123	0.269
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.264
regulation of cellular catabolic process	GO:0031329	101	0.246	Mouse
nucleobase containing small molecule metabolic process	GO:0055086	316	0.232
single organism catabolic process	GO:0044712	283	0.230
ribose phosphate metabolic process	GO:0019693	235	0.217
glycosyl compound catabolic process	GO:1901658	126	0.210
carbohydrate derivative catabolic process	GO:1901136	147	0.203
purine nucleotide catabolic process	GO:0006195	136	0.194
purine ribonucleotide metabolic process	GO:0009150	227	0.191
positive regulation of phosphate metabolic process	GO:0045937	262	0.187
cellular nitrogen compound catabolic process	GO:0044270	163	0.185
carbohydrate derivative metabolic process	GO:1901135	346	0.183
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.182
purine containing compound catabolic process	GO:0072523	138	0.179
organophosphate catabolic process	GO:0046434	148	0.174
organic cyclic compound catabolic process	GO:1901361	175	0.164
ribonucleotide catabolic process	GO:0009261	136	0.161
organonitrogen compound catabolic process	GO:1901565	179	0.159
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.156
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.155
purine containing compound metabolic process	GO:0072521	253	0.154
heterocycle catabolic process	GO:0046700	167	0.151
nucleoside triphosphate metabolic process	GO:0009141	144	0.147
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.146
nucleobase containing compound catabolic process	GO:0034655	152	0.140
macromolecule localization	GO:0033036	252	0.139	Mouse
nucleotide metabolic process	GO:0009117	279	0.131
ribonucleoside metabolic process	GO:0009119	174	0.129
cellular catabolic process	GO:0044248	295	0.128	Mouse
regulation of programmed cell death	GO:0043067	341	0.125
regulation of nucleotide metabolic process	GO:0006140	117	0.125
regulation of catalytic activity	GO:0050790	304	0.122
nucleoside metabolic process	GO:0009116	179	0.119
purine ribonucleotide catabolic process	GO:0009154	136	0.112
purine nucleotide metabolic process	GO:0006163	229	0.108
nucleoside phosphate metabolic process	GO:0006753	283	0.107
organophosphate metabolic process	GO:0019637	370	0.106
purine nucleoside metabolic process	GO:0042278	169	0.106
organic substance catabolic process	GO:1901575	316	0.104	Mouse
negative regulation of apoptotic process	GO:0043066	181	0.104
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.103
nucleotide catabolic process	GO:0009166	139	0.092
positive regulation of response to stimulus	GO:0048584	285	0.090	Mouse
eye morphogenesis	GO:0048592	4	0.090
organelle organization	GO:0006996	266	0.083
organic acid metabolic process	GO:0006082	292	0.083
transcription dna templated	GO:0006351	377	0.080
gtp catabolic process	GO:0006184	71	0.080
regulation of gtpase activity	GO:0043087	57	0.078
regulation of purine nucleotide catabolic process	GO:0033121	65	0.074
regulation of catabolic process	GO:0009894	113	0.073	Mouse
regulation of phosphorus metabolic process	GO:0051174	349	0.071
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.071
ribonucleotide metabolic process	GO:0009259	231	0.069
regulation of purine nucleotide metabolic process	GO:1900542	115	0.068
positive regulation of nucleoside metabolic process	GO:0045979	55	0.064
secretion	GO:0046903	307	0.063	Mouse
purine ribonucleoside monophosphate catabolic process	GO:0009169	55	0.063
regulation of phosphate metabolic process	GO:0019220	349	0.062
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.062
cellular component assembly	GO:0022607	360	0.056
response to extracellular stimulus	GO:0009991	380	0.056
rhythmic process	GO:0048511	156	0.056
nucleic acid templated transcription	GO:0097659	379	0.056
glycosyl compound metabolic process	GO:1901657	182	0.056
nucleoside monophosphate metabolic process	GO:0009123	93	0.055
single organism reproductive process	GO:0044702	297	0.055
regulation of molecular function	GO:0065009	398	0.054
guanosine containing compound catabolic process	GO:1901069	71	0.054
regulation of apoptotic process	GO:0042981	335	0.054
negative regulation of gene expression	GO:0010629	199	0.053	Mouse
ribonucleoside monophosphate catabolic process	GO:0009158	55	0.052
nucleoside monophosphate catabolic process	GO:0009125	56	0.051
purine ribonucleoside catabolic process	GO:0046130	124	0.051
atp catabolic process	GO:0006200	54	0.051
purine nucleoside monophosphate catabolic process	GO:0009128	55	0.050
apoptotic process	GO:0006915	381	0.050
positive regulation of nucleotide metabolic process	GO:0045981	91	0.050
carboxylic acid metabolic process	GO:0019752	289	0.049
gtp metabolic process	GO:0046039	72	0.049
cellular response to stress	GO:0033554	269	0.049
regulation of nucleoside metabolic process	GO:0009118	66	0.048
regulation of rna biosynthetic process	GO:2001141	381	0.047
positive regulation of phosphorus metabolic process	GO:0010562	262	0.046
nucleoside phosphate catabolic process	GO:1901292	140	0.044
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.044
single organism organelle organization	GO:1902589	180	0.043
single organism biosynthetic process	GO:0044711	342	0.042
regulation of transcription dna templated	GO:0006355	374	0.042
cellular ketone metabolic process	GO:0042180	51	0.042
reproductive process	GO:0022414	372	0.042
reproductive system development	GO:0061458	128	0.041
cellular amino acid metabolic process	GO:0006520	107	0.040
response to nutrient levels	GO:0031667	370	0.040
protein localization	GO:0008104	191	0.039	Mouse
positive regulation of molecular function	GO:0044093	230	0.039
cellular component biogenesis	GO:0044085	368	0.039
regulation of nucleotide catabolic process	GO:0030811	65	0.039
oxoacid metabolic process	GO:0043436	290	0.038
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.038
aging	GO:0007568	241	0.037	Fly
positive regulation of hydrolase activity	GO:0051345	86	0.037
regulation of rna metabolic process	GO:0051252	391	0.037
dephosphorylation	GO:0016311	98	0.036
regulation of cell projection organization	GO:0031344	175	0.035
negative regulation of macromolecule metabolic process	GO:0010605	260	0.035	Mouse
positive regulation of catalytic activity	GO:0043085	184	0.035
proteolysis	GO:0006508	175	0.034	Mouse
reproductive structure development	GO:0048608	128	0.032
positive regulation of rna biosynthetic process	GO:1902680	197	0.032
response to ketone	GO:1901654	182	0.031
guanosine containing compound metabolic process	GO:1901068	74	0.031
response to peptide	GO:1901652	292	0.031
ribonucleoside monophosphate metabolic process	GO:0009161	88	0.030
biological adhesion	GO:0022610	110	0.030
neuron apoptotic process	GO:0051402	88	0.029
head development	GO:0060322	247	0.029
regulation of hydrolase activity	GO:0051336	143	0.029
sex differentiation	GO:0007548	113	0.029
regulation of cellular component organization	GO:0051128	368	0.028
neuron death	GO:0070997	127	0.028
chemical homeostasis	GO:0048878	292	0.028
multi organism reproductive process	GO:0044703	262	0.028
negative regulation of programmed cell death	GO:0043069	183	0.027
organelle assembly	GO:0070925	22	0.027
multicellular organism reproduction	GO:0032504	233	0.027
intracellular protein transport	GO:0006886	79	0.026	Mouse
positive regulation of purine nucleotide catabolic process	GO:0033123	53	0.026
axon guidance	GO:0007411	24	0.025
membrane organization	GO:0061024	94	0.025
cell type specific apoptotic process	GO:0097285	134	0.025
regulation of cellular protein metabolic process	GO:0032268	267	0.025	Mouse
gonad development	GO:0008406	104	0.025
establishment of protein localization	GO:0045184	141	0.025	Mouse
detection of temperature stimulus	GO:0016048	4	0.025
development of primary sexual characteristics	GO:0045137	107	0.025
rna biosynthetic process	GO:0032774	380	0.025
cellular macromolecule localization	GO:0070727	122	0.024	Mouse
intracellular signal transduction	GO:0035556	314	0.024	Zebrafish
positive regulation of protein metabolic process	GO:0051247	178	0.024
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.024
positive regulation of catabolic process	GO:0009896	78	0.023
anatomical structure morphogenesis	GO:0009653	298	0.023	Zebrafish Fly
response to hypoxia	GO:0001666	231	0.023
small gtpase mediated signal transduction	GO:0007264	36	0.023
cell migration	GO:0016477	197	0.022	Mouse
negative regulation of signaling	GO:0023057	157	0.022
regulation of nucleic acid templated transcription	GO:1903506	380	0.022
atp metabolic process	GO:0046034	72	0.022
positive regulation of signaling	GO:0023056	270	0.022	Mouse
cellular chemical homeostasis	GO:0055082	247	0.022
negative regulation of cell communication	GO:0010648	158	0.022
regulation of cell morphogenesis	GO:0022604	77	0.022
central nervous system development	GO:0007417	311	0.021
regulation of cellular amino acid metabolic process	GO:0006521	2	0.021
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.021
positive regulation of cellular amine metabolic process	GO:0033240	3	0.021
signal transduction by phosphorylation	GO:0023014	144	0.020	Zebrafish
positive regulation of cellular catabolic process	GO:0031331	71	0.020
cellular amine metabolic process	GO:0044106	38	0.020
regulation of atpase activity	GO:0043462	7	0.020
positive regulation of intracellular signal transduction	GO:1902533	138	0.020
response to growth factor	GO:0070848	189	0.020	Mouse
cellular response to tumor necrosis factor	GO:0071356	46	0.020
cell projection organization	GO:0030030	302	0.019
macromolecular complex assembly	GO:0065003	273	0.019
regulation of signal transduction	GO:0009966	318	0.019	Mouse
regulation of nervous system development	GO:0051960	264	0.019
response to decreased oxygen levels	GO:0036293	237	0.019
developmental process involved in reproduction	GO:0003006	159	0.019
locomotion	GO:0040011	237	0.019	Mouse Fly
protein complex biogenesis	GO:0070271	263	0.019
regulation of dna metabolic process	GO:0051052	60	0.019
negative regulation of protein metabolic process	GO:0051248	114	0.019	Mouse
negative regulation of metabolic process	GO:0009892	331	0.019	Mouse
circadian rhythm	GO:0007623	88	0.019
regulation of protein metabolic process	GO:0051246	289	0.019	Mouse
amine metabolic process	GO:0009308	38	0.018
programmed cell death	GO:0012501	392	0.018
ion transmembrane transport	GO:0034220	365	0.018
regulation of synaptic growth at neuromuscular junction	GO:0008582	1	0.018
synaptic growth at neuromuscular junction	GO:0051124	1	0.018
response to peptide hormone	GO:0043434	278	0.018
protein phosphorylation	GO:0006468	345	0.018	Zebrafish
organic acid transport	GO:0015849	116	0.018	Mouse
signal release	GO:0023061	145	0.018
rna metabolic process	GO:0016070	406	0.017
response to cytokine	GO:0034097	215	0.017
branched chain amino acid metabolic process	GO:0009081	4	0.017
positive regulation of cellular component organization	GO:0051130	200	0.017
regulation of body fluid levels	GO:0050878	90	0.017
regulation of cellular component biogenesis	GO:0044087	86	0.017
positive regulation of signal transduction	GO:0009967	175	0.017	Mouse
macromolecular complex subunit organization	GO:0043933	339	0.017
negative regulation of cell cycle phase transition	GO:1901988	4	0.017
reproduction	GO:0000003	245	0.017
dna metabolic process	GO:0006259	96	0.017
negative regulation of cell death	GO:0060548	229	0.017
cellular component movement	GO:0006928	248	0.017	Mouse
cellular response to cytokine stimulus	GO:0071345	127	0.017
stem cell division	GO:0017145	4	0.017
negative regulation of response to stimulus	GO:0048585	155	0.016
actin myosin filament sliding	GO:0033275	2	0.016
response to corticosteroid	GO:0031960	235	0.016
neuron projection guidance	GO:0097485	24	0.016
single organism intracellular transport	GO:1902582	166	0.016	Mouse
regulation of cellular ketone metabolic process	GO:0010565	27	0.016
positive regulation of cellular protein metabolic process	GO:0032270	167	0.016
cellular homeostasis	GO:0019725	252	0.016
ras protein signal transduction	GO:0007265	29	0.016
regulation of cell proliferation	GO:0042127	359	0.015
positive regulation of neurogenesis	GO:0050769	165	0.015
positive regulation of cell death	GO:0010942	184	0.015
cellular component morphogenesis	GO:0032989	155	0.015
protein complex assembly	GO:0006461	263	0.015
regulation of atp catabolic process	GO:1903289	7	0.015
axonogenesis	GO:0007409	71	0.015
lipid metabolic process	GO:0006629	283	0.015
regulation of gtp catabolic process	GO:0033124	58	0.015
neuron projection development	GO:0031175	273	0.015
regulation of neurogenesis	GO:0050767	247	0.015
peptidyl amino acid modification	GO:0018193	126	0.015
protein complex subunit organization	GO:0071822	302	0.014
regulation of cell differentiation	GO:0045595	320	0.014
regulation of multicellular organismal development	GO:2000026	376	0.014
female gonad development	GO:0008585	53	0.014
cell morphogenesis involved in differentiation	GO:0000904	119	0.014
regulation of locomotion	GO:0040012	148	0.014
response to radiation	GO:0009314	137	0.014
homeostatic process	GO:0042592	331	0.014
positive regulation of nucleotide catabolic process	GO:0030813	53	0.014
microtubule polymerization or depolymerization	GO:0031109	13	0.014
neuron differentiation	GO:0030182	368	0.014
male gonad development	GO:0008584	59	0.014
protein autophosphorylation	GO:0046777	66	0.014
positive regulation of cell proliferation	GO:0008284	249	0.014
antigen processing and presentation	GO:0019882	2	0.013
peptidyl tyrosine phosphorylation	GO:0018108	72	0.013
single organism membrane organization	GO:0044802	74	0.013
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.013
regulation of cellular amine metabolic process	GO:0033238	8	0.013
positive regulation of transcription dna templated	GO:0045893	197	0.013
negative regulation of cell division	GO:0051782	1	0.013
intracellular transport	GO:0046907	185	0.013	Mouse
somatic stem cell maintenance	GO:0035019	2	0.013
regulation of intracellular signal transduction	GO:1902531	218	0.013
negative regulation of cell development	GO:0010721	82	0.013
positive regulation of phosphorylation	GO:0042327	177	0.013
camera type eye development	GO:0043010	48	0.013
cellular response to extracellular stimulus	GO:0031668	73	0.013
negative regulation of cellular protein metabolic process	GO:0032269	106	0.013	Mouse
circadian regulation of gene expression	GO:0032922	3	0.012
cellular protein localization	GO:0034613	122	0.012	Mouse
positive regulation of atpase activity	GO:0032781	6	0.012
eye development	GO:0001654	50	0.012
somatic stem cell division	GO:0048103	2	0.012
localization of cell	GO:0051674	202	0.012	Mouse
immune system process	GO:0002376	204	0.012
peptidyl tyrosine modification	GO:0018212	72	0.012
positive regulation of mitochondrion organization	GO:0010822	4	0.012
male sex differentiation	GO:0046661	64	0.012
asymmetric protein localization	GO:0008105	2	0.012
regulation of membrane potential	GO:0042391	110	0.012
cell cycle	GO:0007049	101	0.012	Human
asymmetric stem cell division	GO:0098722	2	0.012
positive regulation of neuron differentiation	GO:0045666	126	0.012
axon development	GO:0061564	96	0.012
inflammatory response	GO:0006954	150	0.012
circulatory system development	GO:0072359	134	0.012	Zebrafish
sensory organ development	GO:0007423	74	0.012
chemotaxis	GO:0006935	66	0.012
detection of temperature stimulus involved in sensory perception of pain	GO:0050965	4	0.012
development of primary female sexual characteristics	GO:0046545	56	0.012
secretion by cell	GO:0032940	248	0.011	Mouse
positive regulation of apoptotic process	GO:0043065	154	0.011
brain development	GO:0007420	247	0.011
positive regulation of gene expression	GO:0010628	244	0.011
cellular response to nitrogen compound	GO:1901699	210	0.011
carboxylic acid transport	GO:0046942	115	0.011	Mouse
g protein coupled receptor signaling pathway	GO:0007186	242	0.011
body fluid secretion	GO:0007589	41	0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process	GO:0031145	1	0.011
sexual reproduction	GO:0019953	148	0.011
ion homeostasis	GO:0050801	212	0.011
macroautophagy	GO:0016236	4	0.011
multicellular organismal reproductive process	GO:0048609	233	0.011
negative regulation of rna metabolic process	GO:0051253	123	0.011
negative regulation of rna biosynthetic process	GO:1902679	118	0.011
mitotic sister chromatid separation	GO:0051306	1	0.011
response to estrogen	GO:0043627	232	0.011
cell adhesion	GO:0007155	110	0.011
cytoplasmic transport	GO:0016482	115	0.011
regulation of microtubule polymerization or depolymerization	GO:0031110	12	0.011
cellular response to endogenous stimulus	GO:0071495	377	0.011	Mouse
amide transport	GO:0042886	105	0.011
regulation of protein modification process	GO:0031399	194	0.011
glial cell differentiation	GO:0010001	65	0.010
regulation of atp metabolic process	GO:1903578	9	0.010
negative regulation of neuron death	GO:1901215	69	0.010
wound healing spreading of cells	GO:0044319	2	0.010
response to inorganic substance	GO:0010035	377	0.010
organic acid biosynthetic process	GO:0016053	83	0.010
hormone secretion	GO:0046879	115	0.010
mitotic sister chromatid segregation	GO:0000070	1	0.010
sensory perception	GO:0007600	101	0.010
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	4	0.010
oligodendrocyte differentiation	GO:0048709	32	0.010
positive regulation of cellular biosynthetic process	GO:0031328	295	0.010
regulation of cell growth	GO:0001558	85	0.010

Gipc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.069
nervous system disease	DOID:863	0.069
neuropathy	DOID:870	0.023
disease of cellular proliferation	DOID:14566	0.018
sensory system disease	DOID:0050155	0.017
cancer	DOID:162	0.013
organ system cancer	DOID:0050686	0.013

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