Rattus norvegicus

20 known processes

Cldn4

claudin 4

Cldn4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron developmentGO:00486662860.177
multi organism reproductive processGO:00447032620.116
cellular component assemblyGO:00226073600.110
reproductive processGO:00224143720.109
intracellular signal transductionGO:00355563140.108
anatomical structure morphogenesisGO:00096532980.105
neurological system processGO:00508772190.104
response to inorganic substanceGO:00100353770.090
regulation of catalytic activityGO:00507903040.089
response to bacteriumGO:00096172000.088
cellular response to oxygen containing compoundGO:19017013860.087
blood circulationGO:00080151830.087
cellular component biogenesisGO:00440853680.087
tissue developmentGO:00098882520.086
single organism reproductive processGO:00447022970.072
neuron differentiationGO:00301823680.071
regulation of phosphate metabolic processGO:00192203490.070
positive regulation of phosphate metabolic processGO:00459372620.067
cellular component morphogenesisGO:00329891550.066
regulation of system processGO:00440572080.065
regulation of protein metabolic processGO:00512462890.064
cellular response to peptideGO:19016531330.062
macromolecular complex subunit organizationGO:00439333390.060
cell projection organizationGO:00300303020.058
macromolecular complex assemblyGO:00650032730.057
regulation of molecular functionGO:00650093980.056
carboxylic acid metabolic processGO:00197522890.054
cellular component movementGO:00069282480.054
cellular response to endogenous stimulusGO:00714953770.053
response to woundingGO:00096112540.053
regulation of multicellular organismal developmentGO:20000263760.052
locomotionGO:00400112370.051
regulation of cellular amino acid metabolic processGO:000652120.048
protein complex biogenesisGO:00702712630.047
secretionGO:00469033070.047
single organism catabolic processGO:00447122830.047
multicellular organism reproductionGO:00325042330.047
nucleobase containing small molecule metabolic processGO:00550863160.044
response to ketoneGO:19016541820.044
response to metal ionGO:00100382530.043
agingGO:00075682410.042
regulation of cell projection organizationGO:00313441750.042
epithelial cell differentiationGO:0030855710.041
organonitrogen compound catabolic processGO:19015651790.041
protein complex subunit organizationGO:00718223020.041
sexual reproductionGO:00199531480.041
nucleotide metabolic processGO:00091172790.040
cell morphogenesisGO:00009021420.039
positive regulation of programmed cell deathGO:00430681570.038
cellular catabolic processGO:00442482950.037
behaviorGO:00076102050.037
action potentialGO:0001508540.037
cellular amino acid metabolic processGO:00065201070.037
multicellular organismal reproductive processGO:00486092330.037
regulation of anatomical structure morphogenesisGO:00226031410.036
regulation of nervous system developmentGO:00519602640.036
synaptic transmissionGO:00072682350.036
cell morphogenesis involved in differentiationGO:00009041190.035
neuron projection developmentGO:00311752730.034
response to oxidative stressGO:00069791860.034
sensory perceptionGO:00076001010.034
cytoskeleton organizationGO:00070101110.033
single organism biosynthetic processGO:00447113420.033
regulation of protein modification processGO:00313991940.033
response to lipopolysaccharideGO:00324961910.033
protein phosphorylationGO:00064683450.033
cellular ketone metabolic processGO:0042180510.033
organic substance catabolic processGO:19015753160.033
positive regulation of response to stimulusGO:00485842850.032
carbohydrate derivative metabolic processGO:19011353460.032
oxoacid metabolic processGO:00434362900.032
positive regulation of phosphorus metabolic processGO:00105622620.032
response to estrogenGO:00436272320.032
glycosyl compound metabolic processGO:19016571820.032
purine nucleotide metabolic processGO:00061632290.032
response to hydrogen peroxideGO:0042542890.031
membrane organizationGO:0061024940.031
reproductive system developmentGO:00614581280.031
wound healingGO:00420601220.031
cellular response to stressGO:00335542690.031
regulation of protein phosphorylationGO:00019321830.030
regulation of neuron differentiationGO:00456642080.030
protein complex assemblyGO:00064612630.030
positive regulation of nitrogen compound metabolic processGO:00511733340.030
signal transduction by phosphorylationGO:00230141440.030
heterocycle catabolic processGO:00467001670.029
purine nucleoside triphosphate metabolic processGO:00091441410.029
regulation of neuron projection developmentGO:00109751610.029
nucleic acid templated transcriptionGO:00976593790.029
hormone metabolic processGO:0042445690.029
single organism organelle organizationGO:19025891800.028
response to radiationGO:00093141370.028
nucleoside metabolic processGO:00091161790.028
regulation of immune response to tumor cellGO:000283730.027
chemical homeostasisGO:00488782920.027
organic cyclic compound catabolic processGO:19013611750.027
purine containing compound metabolic processGO:00725212530.027
purine ribonucleotide metabolic processGO:00091502270.027
regulation of immune system processGO:00026821230.027
positive regulation of locomotionGO:00400171020.027
gamete generationGO:00072761240.027
positive regulation of cell developmentGO:00107201760.027
apoptotic processGO:00069153810.027
regulation of cell differentiationGO:00455953200.027
single organism membrane organizationGO:0044802740.026
organelle organizationGO:00069962660.026
regulation of cell developmentGO:00602842630.026
regulation of neurogenesisGO:00507672470.026
positive regulation of cellular component organizationGO:00511302000.026
positive regulation of neurogenesisGO:00507691650.026
cellular response to tumor necrosis factorGO:0071356460.025
epithelium developmentGO:0060429960.025
cellular response to nitrogen compoundGO:19016992100.025
positive regulation of catalytic activityGO:00430851840.025
ribonucleoside metabolic processGO:00091191740.025
positive regulation of cell projection organizationGO:00313461110.025
regulation of cellular protein metabolic processGO:00322682670.025
regulation of cellular ketone metabolic processGO:0010565270.025
ribonucleotide metabolic processGO:00092592310.025
immune system processGO:00023762040.025
glial cell differentiationGO:0010001650.025
response to acid chemicalGO:00011012220.025
regulation of cellular amine metabolic processGO:003323880.024
regulation of phosphorus metabolic processGO:00511743490.024
secretion by cellGO:00329402480.024
rna biosynthetic processGO:00327743800.024
nucleoside phosphate metabolic processGO:00067532830.024
regulation of synaptic transmissionGO:00508041410.024
urogenital system developmentGO:0001655780.024
regulation of intracellular signal transductionGO:19025312180.024
regulation of phosphorylationGO:00423252480.024
ribose phosphate metabolic processGO:00196932350.024
cellular response to peptide hormone stimulusGO:00713751200.023
small gtpase mediated signal transductionGO:0007264360.023
negative regulation of macromolecule metabolic processGO:00106052600.023
positive regulation of gene expressionGO:00106282440.023
proteolysisGO:00065081750.023
circulatory system processGO:00030131830.022
regulation of transcription from rna polymerase ii promoterGO:00063572340.022
purine ribonucleoside metabolic processGO:00461281680.022
catabolic processGO:00090563510.022
response to other organismGO:00517072200.022
metal ion transportGO:00300012890.022
positive regulation of molecular functionGO:00440932300.022
cellular response to lipidGO:00713962010.022
response to alkaloidGO:00432791320.022
cell motilityGO:00488702020.021
regulation of membrane potentialGO:00423911100.021
purine containing compound catabolic processGO:00725231380.021
negative regulation of protein metabolic processGO:00512481140.021
cell projection morphogenesisGO:00488581230.021
regulation of signal transductionGO:00099663180.021
female pregnancyGO:00075651220.021
homeostatic processGO:00425923310.021
response to estradiolGO:00323551640.021
protein oligomerizationGO:00512591910.021
axon developmentGO:0061564960.021
macromolecule localizationGO:00330362520.021
regulation of apoptotic processGO:00429813350.021
purine nucleoside metabolic processGO:00422781690.021
defense responseGO:00069521940.020
positive regulation of protein metabolic processGO:00512471780.020
myelinationGO:0042552390.020
regulation of cellular component organizationGO:00511283680.020
regulation of hormone levelsGO:00108171870.020
organophosphate catabolic processGO:00464341480.020
ras protein signal transductionGO:0007265290.020
negative regulation of phosphorus metabolic processGO:0010563800.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
positive regulation of cell differentiationGO:00455972170.020
negative regulation of response to stimulusGO:00485851550.020
developmental process involved in reproductionGO:00030061590.020
response to toxic substanceGO:00096361330.020
localization of cellGO:00516742020.019
response to monosaccharideGO:00342841590.019
regulation of secretionGO:00510462240.019
regulation of protein kinase activityGO:00458591050.019
cellular response to hormone stimulusGO:00328702470.019
regulation of mapk cascadeGO:00434081160.019
regulation of cellular component biogenesisGO:0044087860.019
response to molecule of bacterial originGO:00022371940.019
cellular response to growth factor stimulusGO:00713631620.019
nucleoside catabolic processGO:00091641260.019
response to extracellular stimulusGO:00099913800.019
positive regulation of signalingGO:00230562700.019
positive regulation of cellular amine metabolic processGO:003324030.019
gland developmentGO:00487321550.018
negative regulation of cellular metabolic processGO:00313242810.018
ribonucleoside monophosphate metabolic processGO:0009161880.018
synaptic growth at neuromuscular junctionGO:005112410.018
cell morphogenesis involved in neuron differentiationGO:00486671060.018
cell part morphogenesisGO:00329901230.018
negative regulation of cellular protein metabolic processGO:00322691060.018
programmed cell deathGO:00125013920.018
brain developmentGO:00074202470.018
regulation of cellular component movementGO:00512701500.018
organophosphate metabolic processGO:00196373700.018
positive regulation of phosphorylationGO:00423271770.018
regulation of cell motilityGO:20001451310.018
purine ribonucleoside triphosphate catabolic processGO:00092071220.017
cytokine biosynthetic processGO:004208930.017
mapk cascadeGO:00001651400.017
cation transportGO:00068123820.017
cellular calcium ion homeostasisGO:00068741600.017
positive regulation of protein modification processGO:00314011420.017
regulation of cell migrationGO:00303341280.017
regulation of tube sizeGO:0035150890.017
negative regulation of metabolic processGO:00098923310.017
cellular carbohydrate metabolic processGO:0044262720.017
regulation of cell morphogenesis involved in differentiationGO:0010769720.017
response to growth factorGO:00708481890.017
negative regulation of molecular functionGO:00440921330.017
response to retinoic acidGO:0032526630.017
response to vitaminGO:00332731310.017
cellular response to organonitrogen compoundGO:00714171970.017
negative regulation of multicellular organismal processGO:00512412030.017
cardiac conductionGO:006133720.017
metal ion homeostasisGO:00550651860.017
reproductionGO:00000032450.016
organophosphate biosynthetic processGO:00904071430.016
response to nutrient levelsGO:00316673700.016
glycosyl compound catabolic processGO:19016581260.016
cellular nitrogen compound catabolic processGO:00442701630.016
purine ribonucleotide catabolic processGO:00091541360.016
response to cytokineGO:00340972150.016
negative regulation of developmental processGO:00510931250.016
regulation of cell proliferationGO:00421273590.016
transcription dna templatedGO:00063513770.016
chemotaxisGO:0006935660.016
cognitionGO:0050890920.016
single organism cellular localizationGO:19025801020.016
single organism behaviorGO:00447081300.016
negative regulation of cell deathGO:00605482290.016
spermatogenesisGO:0007283990.016
vesicle mediated transportGO:00161921810.016
positive regulation of developmental processGO:00510942830.016
response to carbohydrateGO:00097431830.016
response to peptideGO:19016522920.016
negative regulation of cell communicationGO:00106481580.016
response to high density lipoprotein particleGO:005509920.016
ensheathment of neuronsGO:0007272400.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
gliogenesisGO:0042063930.016
development of primary sexual characteristicsGO:00451371070.015
actin filament based processGO:0030029860.015
neuron projection morphogenesisGO:00488121220.015
cellular component maintenanceGO:004395440.015
cell migrationGO:00164771970.015
negative regulation of cell developmentGO:0010721820.015
cellular response to extracellular stimulusGO:0031668730.015
positive regulation of cell deathGO:00109421840.015
amine metabolic processGO:0009308380.015
positive regulation of nervous system developmentGO:00519621780.015
nucleoside triphosphate catabolic processGO:00091431230.015
regulation of transferase activityGO:00513381230.015
positive regulation of neuron projection developmentGO:0010976990.015
positive regulation of biosynthetic processGO:00098913190.015
regulation of blood circulationGO:19035221100.015
response to glucocorticoidGO:00513842230.015
positive regulation of ion transportGO:0043270940.015
cell growthGO:00160491040.015
negative regulation of cell proliferationGO:00082851190.015
ribonucleoside triphosphate metabolic processGO:00091991410.015
regulation of synaptic plasticityGO:0048167700.015
organonitrogen compound biosynthetic processGO:19015661670.015
axon ensheathmentGO:0008366400.014
nucleoside triphosphate metabolic processGO:00091411440.014
cellular amine metabolic processGO:0044106380.014
cellular cation homeostasisGO:00300031800.014
regulation of nucleic acid templated transcriptionGO:19035063800.014
positive regulation of cell communicationGO:00106472710.014
positive regulation of protein phosphorylationGO:00019341350.014
negative regulation of nervous system developmentGO:0051961790.014
regulation of cell morphogenesisGO:0022604770.014
gonad developmentGO:00084061040.014
regulation of cytokine biosynthetic processGO:004203530.014
nucleotide catabolic processGO:00091661390.014
positive regulation of multicellular organismal processGO:00512403870.014
purine ribonucleoside catabolic processGO:00461301240.014
neuronal action potentialGO:0019228350.014
positive regulation of growthGO:0045927550.014
reactive oxygen species metabolic processGO:0072593370.014
positive regulation of cellular protein metabolic processGO:00322701670.014
negative regulation of phosphate metabolic processGO:0045936800.014
erk1 and erk2 cascadeGO:0070371480.014
cell cycleGO:00070491010.014
regulation of growthGO:00400081050.014
response to nutrientGO:00075842480.014
response to reactive oxygen speciesGO:00003021200.013
response to hypoxiaGO:00016662310.013
rhythmic processGO:00485111560.013
response to ionizing radiationGO:0010212590.013
negative regulation of gene expressionGO:00106291990.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.013
cofactor metabolic processGO:0051186950.013
regenerationGO:00310991630.013
peptidyl tyrosine phosphorylationGO:0018108720.013
regulation of anatomical structure sizeGO:00900661350.013
lipid metabolic processGO:00066292830.013
regulation of cellular localizationGO:00603412630.013
male gamete generationGO:0048232990.013
negative regulation of catalytic activityGO:00430861030.013
response to external biotic stimulusGO:00432072210.013
olfactory behaviorGO:004204820.013
cellular response to acid chemicalGO:0071229750.013
regulation of dendrite developmentGO:0050773590.013
calcium ion homeostasisGO:00550741620.013
cellular amide metabolic processGO:0043603440.013
rho protein signal transductionGO:0007266110.013
regulation of angiogenesisGO:0045765390.013
protein localization to membraneGO:0072657360.013
ion homeostasisGO:00508012120.013
organic acid metabolic processGO:00060822920.013
cellular response to biotic stimulusGO:0071216590.013
purine ribonucleoside triphosphate metabolic processGO:00092051400.013
nucleoside monophosphate metabolic processGO:0009123930.013
negative regulation of biosynthetic processGO:00098901680.013
response to axon injuryGO:0048678590.013
protein maturationGO:0051604680.012
fertilizationGO:000956630.012
positive regulation of cellular biosynthetic processGO:00313282950.012
circulatory system developmentGO:00723591340.012
nucleobase containing compound catabolic processGO:00346551520.012
response to progesteroneGO:0032570480.012
negative regulation of neurogenesisGO:0050768780.012
positive regulation of signal transductionGO:00099671750.012
purine nucleoside triphosphate catabolic processGO:00091461220.012
response to tumor necrosis factorGO:0034612560.012
kidney developmentGO:0001822670.012
multicellular organismal signalingGO:0035637440.012
positive regulation of cellular component movementGO:00512721020.012
transmission of nerve impulseGO:0019226420.012
rna metabolic processGO:00160704060.012
response to peptide hormoneGO:00434342780.012
sex differentiationGO:00075481130.012
positive regulation of erk1 and erk2 cascadeGO:0070374290.012
regulation of small gtpase mediated signal transductionGO:0051056480.012
positive regulation of nucleic acid templated transcriptionGO:19035081970.012
negative regulation of nitrogen compound metabolic processGO:00511721610.012
positive regulation of neuron differentiationGO:00456661260.012
response to corticosteroidGO:00319602350.012
purine nucleotide catabolic processGO:00061951360.012
muscle system processGO:00030121150.012
t cell extravasationGO:007268310.012
cd8 positive alpha beta t cell extravasationGO:003569700.012
regulation of metal ion transportGO:00109591180.012
cardiac muscle contractionGO:0060048270.012
actin cytoskeleton organizationGO:0030036730.012
transmembrane transportGO:00550854120.012
reactive nitrogen species metabolic processGO:200105710.012
negative regulation of cellular component organizationGO:0051129830.012
male sex differentiationGO:0046661640.012
response to insulinGO:00328681330.011
positive regulation of transferase activityGO:0051347810.011
regulation of map kinase activityGO:0043405530.011
muscle cell proliferationGO:0033002840.011
regulation of secretion by cellGO:19035302080.011
circadian rhythmGO:0007623880.011
lipid localizationGO:0010876620.011
regulation of purine nucleotide metabolic processGO:19005421150.011
cation homeostasisGO:00550801950.011
regulation of actin filament based processGO:0032970420.011
regulation of kinase activityGO:00435491170.011
positive regulation of mapk cascadeGO:0043410920.011
cell adhesionGO:00071551100.011
regulation of cell activationGO:0050865500.011
peptidyl tyrosine modificationGO:0018212720.011
cellular response to nutrient levelsGO:0031669600.011
ribonucleoside catabolic processGO:00424541260.011
g protein coupled receptor signaling pathwayGO:00071862420.011
positive regulation of macromolecule biosynthetic processGO:00105572470.011
cellular macromolecular complex assemblyGO:0034622580.011
cellular response to organic cyclic compoundGO:00714072020.011
regulation of hydrolase activityGO:00513361430.011
chemosensory behaviorGO:000763520.011
negative regulation of apoptotic processGO:00430661810.011
organic hydroxy compound transportGO:0015850770.011
regulation of ion transportGO:00432692450.011
positive regulation of cellular component biogenesisGO:0044089550.011
cellular response to abiotic stimulusGO:0071214850.011
ribonucleoside monophosphate catabolic processGO:0009158550.011
protein processingGO:0016485680.011
regulation of response to woundingGO:1903034690.011
cellular response to external stimulusGO:00714961180.011
aromatic compound catabolic processGO:00194391680.011
regulation of rna metabolic processGO:00512523910.011
negative regulation of signalingGO:00230571570.011
single organism carbohydrate metabolic processGO:00447231180.011
defense response to gram negative bacteriumGO:005082930.010
regulation of programmed cell deathGO:00430673410.010
meiotic cell cycle processGO:190304630.010
growthGO:00400071650.010
negative regulation of programmed cell deathGO:00430691830.010
monocarboxylic acid transportGO:0015718520.010
carbohydrate derivative catabolic processGO:19011361470.010
multi multicellular organism processGO:00447061380.010
positive regulation of blood circulationGO:1903524650.010
regulation of erk1 and erk2 cascadeGO:0070372410.010
cellular metal ion homeostasisGO:00068751720.010
sensory perception of painGO:0019233730.010
response to light stimulusGO:0009416520.010
axis specificationGO:000979840.010
ribonucleotide catabolic processGO:00092611360.010
regulation of rna biosynthetic processGO:20011413810.010
purine nucleotide biosynthetic processGO:0006164830.010
lipid storageGO:001991510.010

Cldn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.020
nervous system diseaseDOID:86300.020
organ system cancerDOID:005068600.015
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015