Rattus norvegicus

99 known processes

Cast

calpastatin

(Aliases: MGC108997)

Cast biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein complex assemblyGO:00064612630.595
regulation of cellular component movementGO:00512701500.572
macromolecular complex assemblyGO:00650032730.469
macromolecular complex subunit organizationGO:00439333390.431
protein complex subunit organizationGO:00718223020.418
locomotionGO:00400112370.409
synaptic growth at neuromuscular junctionGO:005112410.374
transcription dna templatedGO:00063513770.346
regulation of cellular protein metabolic processGO:00322682670.345
response to decreased oxygen levelsGO:00362932370.335
neuron differentiationGO:00301823680.331
enzyme linked receptor protein signaling pathwayGO:00071671160.327
protein phosphorylationGO:00064683450.326
regulation of protein transportGO:0051223680.325
cellular component biogenesisGO:00440853680.324
programmed cell deathGO:00125013920.321
regulation of cellular component organizationGO:00511283680.316
cell morphogenesisGO:00009021420.290
cellular response to endogenous stimulusGO:00714953770.285
protein complex biogenesisGO:00702712630.279
macromolecule localizationGO:00330362520.278
protein localizationGO:00081041910.254
tissue developmentGO:00098882520.245
cellular response to stressGO:00335542690.245
agingGO:00075682410.223
regulation of protein localizationGO:0032880810.219
response to oxygen levelsGO:00704822650.219
cellular response to peptide hormone stimulusGO:00713751200.207
cellular response to peptideGO:19016531330.207
cellular component assemblyGO:00226073600.205
response to hypoxiaGO:00016662310.205
positive regulation of biosynthetic processGO:00098913190.200
vesicle mediated transportGO:00161921810.198
protein transportGO:00150311320.198
response to glucocorticoidGO:00513842230.196
cell motilityGO:00488702020.194
endocytosisGO:0006897840.187
single organism organelle organizationGO:19025891800.186
response to insulinGO:00328681330.184
positive regulation of molecular functionGO:00440932300.183
regulation of secretion by cellGO:19035302080.180
cellular response to hormone stimulusGO:00328702470.178
lens development in camera type eyeGO:0002088130.173
nucleoside triphosphate metabolic processGO:00091411440.172
positive regulation of multicellular organismal processGO:00512403870.168
response to cytokineGO:00340972150.167
actin cytoskeleton organizationGO:0030036730.162
regulation of cell developmentGO:00602842630.162
cytoskeleton organizationGO:00070101110.152
regulation of phosphate metabolic processGO:00192203490.151
cellular catabolic processGO:00442482950.151
multi organism reproductive processGO:00447032620.150
regulation of cell differentiationGO:00455953200.145
negative regulation of metabolic processGO:00098923310.145
carbohydrate derivative metabolic processGO:19011353460.144
secretionGO:00469033070.143
positive regulation of cell developmentGO:00107201760.142
organophosphate metabolic processGO:00196373700.140
regulation of cellular localizationGO:00603412630.140
establishment of protein localizationGO:00451841410.137
positive regulation of catalytic activityGO:00430851840.136
protein autophosphorylationGO:0046777660.136
response to acid chemicalGO:00011012220.135
regulation of establishment of protein localizationGO:0070201690.135
positive regulation of cell communicationGO:00106472710.135
regulation of protein metabolic processGO:00512462890.128
positive regulation of response to stimulusGO:00485842850.127
organophosphate catabolic processGO:00464341480.126
response to estradiolGO:00323551640.126
positive regulation of protein metabolic processGO:00512471780.126
purine nucleoside catabolic processGO:00061521240.126
regulation of apoptotic processGO:00429813350.125
positive regulation of transportGO:00510502450.120
positive regulation of macromolecule biosynthetic processGO:00105572470.120
cellular component movementGO:00069282480.119
actin filament based movementGO:0030048160.119
regulation of protein modification processGO:00313991940.117
positive regulation of cellular protein metabolic processGO:00322701670.117
response to extracellular stimulusGO:00099913800.117
neuron developmentGO:00486662860.115
reproductive system developmentGO:00614581280.115
positive regulation of phosphate metabolic processGO:00459372620.114
neuron projection developmentGO:00311752730.114
cell morphogenesis involved in differentiationGO:00009041190.113
negative regulation of cell deathGO:00605482290.111
positive regulation of apoptotic processGO:00430651540.109
peptidyl amino acid modificationGO:00181931260.108
regulation of cellular component biogenesisGO:0044087860.108
response to nutrient levelsGO:00316673700.105
cell projection organizationGO:00300303020.105
cell migrationGO:00164771970.105
cellular protein catabolic processGO:0044257190.101
regulation of phosphorus metabolic processGO:00511743490.098
positive regulation of signalingGO:00230562700.098
negative regulation of organ growthGO:004662130.096
response to estrogenGO:00436272320.093
positive regulation of nitrogen compound metabolic processGO:00511733340.093
regulation of protein phosphorylationGO:00019321830.093
single organism cellular localizationGO:19025801020.093
gland developmentGO:00487321550.093
response to inorganic substanceGO:00100353770.092
cellular response to organonitrogen compoundGO:00714171970.092
regulation of molecular functionGO:00650093980.091
regulation of secretionGO:00510462240.091
regulation of cell motilityGO:20001451310.090
regenerationGO:00310991630.090
response to ethanolGO:00454711620.090
actin filament based processGO:0030029860.089
peptidyl tyrosine phosphorylationGO:0018108720.089
regulation of mesenchymal cell proliferationGO:001046440.089
cellular response to oxygen containing compoundGO:19017013860.088
localization of cellGO:00516742020.087
positive regulation of programmed cell deathGO:00430681570.087
multicellular organism reproductionGO:00325042330.086
regulation of programmed cell deathGO:00430673410.086
nucleoside phosphate catabolic processGO:19012921400.086
reproductionGO:00000032450.085
nucleic acid templated transcriptionGO:00976593790.084
regulation of kinase activityGO:00435491170.083
response to hydrogen peroxideGO:0042542890.081
cellular component morphogenesisGO:00329891550.080
positive regulation of cell deathGO:00109421840.079
purine ribonucleoside triphosphate metabolic processGO:00092051400.079
rna metabolic processGO:00160704060.078
response to alkaloidGO:00432791320.078
organelle organizationGO:00069962660.077
protein heterooligomerizationGO:0051291890.077
response to corticosteroidGO:00319602350.076
organ regenerationGO:00311001010.076
purine nucleoside monophosphate catabolic processGO:0009128550.076
positive regulation of phosphorylationGO:00423271770.075
regulation of cell migrationGO:00303341280.075
heart morphogenesisGO:000300730.075
negative regulation of macromolecule metabolic processGO:00106052600.075
positive regulation of phosphorus metabolic processGO:00105622620.075
atp catabolic processGO:0006200540.075
activation of jak2 kinase activityGO:004297720.074
multi multicellular organism processGO:00447061380.074
positive regulation of protein modification processGO:00314011420.073
regulation of mapk cascadeGO:00434081160.073
regulation of endothelial cell differentiationGO:004560140.072
homeostatic processGO:00425923310.071
reproductive processGO:00224143720.071
positive regulation of gene expressionGO:00106282440.071
regulation of nervous system developmentGO:00519602640.071
response to hexoseGO:00097461440.070
regulation of cell adhesionGO:0030155520.069
positive regulation of smooth muscle cell proliferationGO:0048661510.069
cellular protein complex assemblyGO:0043623440.068
multicellular organismal reproductive processGO:00486092330.068
regulation of rna metabolic processGO:00512523910.068
regulation of lymphocyte migrationGO:200040110.067
muscle structure developmentGO:0061061870.067
regulation of phosphorylationGO:00423252480.067
negative regulation of cellular response to insulin stimulusGO:1900077110.066
transforming growth factor beta receptor complex assemblyGO:000718120.066
single organism carbohydrate metabolic processGO:00447231180.066
receptor mediated endocytosisGO:0006898420.066
regulation of neuron deathGO:19012141150.066
negative regulation of programmed cell deathGO:00430691830.065
response to peptide hormoneGO:00434342780.065
response to peptideGO:19016522920.064
regulation of locomotionGO:00400121480.064
growthGO:00400071650.064
negative regulation of transportGO:00510511360.063
secretion by cellGO:00329402480.062
positive regulation of cell differentiationGO:00455972170.062
ion homeostasisGO:00508012120.061
dendrite developmentGO:0016358720.061
positive regulation of nervous system developmentGO:00519621780.061
positive regulation of nucleobase containing compound metabolic processGO:00459353190.061
response to glucoseGO:00097491360.061
ribonucleoside monophosphate metabolic processGO:0009161880.060
heterocycle catabolic processGO:00467001670.060
regulation of cell proliferationGO:00421273590.060
cellular homeostasisGO:00197252520.060
nucleoside triphosphate catabolic processGO:00091431230.060
vasculogenesisGO:000157030.060
single organism reproductive processGO:00447022970.060
nucleotide metabolic processGO:00091172790.060
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.059
organic acid metabolic processGO:00060822920.059
positive regulation of cellular component organizationGO:00511302000.058
regulation of protein secretionGO:0050708280.058
signal transduction by phosphorylationGO:00230141440.058
cell junction assemblyGO:0034329180.057
response to monosaccharideGO:00342841590.057
nucleobase containing small molecule metabolic processGO:00550863160.056
purine ribonucleoside catabolic processGO:00461301240.056
nucleoside metabolic processGO:00091161790.055
positive regulation of developmental processGO:00510942830.055
metal ion transportGO:00300012890.055
neuron projection morphogenesisGO:00488121220.055
common partner smad protein phosphorylationGO:000718210.055
purine nucleoside triphosphate metabolic processGO:00091441410.055
wound healingGO:00420601220.055
ribonucleoside catabolic processGO:00424541260.055
regulation of actin cytoskeleton organizationGO:0032956300.054
activation of protein kinase activityGO:0032147470.054
negative regulation of multicellular organismal processGO:00512412030.054
regulation of cell morphogenesisGO:0022604770.053
regulation of catalytic activityGO:00507903040.052
carbohydrate metabolic processGO:00059751300.052
development of primary sexual characteristicsGO:00451371070.052
heart developmentGO:0007507720.052
positive regulation of secretionGO:00510471400.051
positive regulation of cell projection organizationGO:00313461110.051
protein o linked glycosylationGO:000649320.051
anterior posterior pattern specificationGO:000995210.051
response to nutrientGO:00075842480.051
neurological system processGO:00508772190.051
nucleoside monophosphate catabolic processGO:0009125560.050
carboxylic acid metabolic processGO:00197522890.050
receptor metabolic processGO:0043112180.050
regulation of rna biosynthetic processGO:20011413810.050
chemical homeostasisGO:00488782920.050
regulation of cellular catabolic processGO:00313291010.050
regulation of t cell chemotaxisGO:001081910.050
apoptotic processGO:00069153810.049
regulation of neuron projection developmentGO:00109751610.049
cellular metal ion homeostasisGO:00068751720.049
purine ribonucleotide metabolic processGO:00091502270.048
ribonucleotide metabolic processGO:00092592310.048
cellular response to lipidGO:00713962010.048
purine nucleoside metabolic processGO:00422781690.048
response to oxidative stressGO:00069791860.048
organic substance catabolic processGO:19015753160.048
proteolysis involved in cellular protein catabolic processGO:0051603190.048
positive regulation of signal transductionGO:00099671750.047
neuron deathGO:00709971270.047
purine nucleoside triphosphate catabolic processGO:00091461220.047
cellular ion homeostasisGO:00068731840.046
cell projection morphogenesisGO:00488581230.046
positive regulation of cellular biosynthetic processGO:00313282950.046
cellular response to insulin stimulusGO:0032869810.046
anatomical structure morphogenesisGO:00096532980.046
cellular amino acid metabolic processGO:00065201070.046
response to temperature stimulusGO:0009266940.046
anatomical structure formation involved in morphogenesisGO:0048646830.046
positive regulation of skeletal muscle tissue regenerationGO:004341510.045
reproductive structure developmentGO:00486081280.045
negative regulation of cardiac muscle tissue developmentGO:005502630.045
single organism biosynthetic processGO:00447113420.045
response to carbohydrateGO:00097431830.044
single organism catabolic processGO:00447122830.044
purine ribonucleoside metabolic processGO:00461281680.044
positive regulation of protein transportGO:0051222410.044
cell cell signalingGO:00072673350.044
cellular nitrogen compound catabolic processGO:00442701630.043
regulation of catabolic processGO:00098941130.043
cation transportGO:00068123820.043
nucleobase containing compound catabolic processGO:00346551520.043
neuron apoptotic processGO:0051402880.042
cellular response to growth factor stimulusGO:00713631620.042
regulation of multicellular organismal developmentGO:20000263760.042
regulation of synaptic growth at neuromuscular junctionGO:000858210.042
nucleoside catabolic processGO:00091641260.042
dna metabolic processGO:0006259960.042
negative regulation of cellular metabolic processGO:00313242810.041
purine nucleotide metabolic processGO:00061632290.041
positive regulation of secretion by cellGO:19035321280.041
purine ribonucleoside triphosphate catabolic processGO:00092071220.041
organic cyclic compound catabolic processGO:19013611750.041
response to purine containing compoundGO:00140741260.041
regulation of neuron differentiationGO:00456642080.041
multicellular organism growthGO:003526410.041
positive regulation of neurogenesisGO:00507691650.040
cell adhesionGO:00071551100.040
regulation of anatomical structure morphogenesisGO:00226031410.040
development of primary female sexual characteristicsGO:0046545560.039
regulation of cellular ketone metabolic processGO:0010565270.039
gonad developmentGO:00084061040.039
positive regulation of nucleic acid templated transcriptionGO:19035081970.039
epithelial cell differentiationGO:0030855710.039
response to metal ionGO:00100382530.039
locomotory exploration behaviorGO:003564110.038
intracellular signal transductionGO:00355563140.038
purine ribonucleotide catabolic processGO:00091541360.038
cell morphogenesis involved in neuron differentiationGO:00486671060.038
transcription from rna polymerase ii promoterGO:00063662520.038
positive regulation of cellular amine metabolic processGO:003324030.037
rna biosynthetic processGO:00327743800.037
cellular macromolecular complex assemblyGO:0034622580.037
regulation of cell projection organizationGO:00313441750.037
ovulation cycleGO:0042698670.037
head developmentGO:00603222470.036
regulation of skeletal muscle tissue regenerationGO:004341620.036
response to lipopolysaccharideGO:00324961910.036
positive regulation of protein phosphorylationGO:00019341350.036
aromatic compound catabolic processGO:00194391680.035
ribonucleotide catabolic processGO:00092611360.035
cation homeostasisGO:00550801950.035
intracellular transportGO:00469071850.035
positive regulation of cellular amino acid metabolic processGO:004576410.035
dendrite morphogenesisGO:0048813430.035
cellular macromolecule localizationGO:00707271220.035
regulation of transcription from rna polymerase ii promoterGO:00063572340.034
cognitionGO:0050890920.034
central nervous system developmentGO:00074173110.034
glycosyl compound metabolic processGO:19016571820.034
embryonic skeletal system developmentGO:004870630.034
biological adhesionGO:00226101100.034
cellular response to steroid hormone stimulusGO:0071383930.034
catabolic processGO:00090563510.034
cellular protein localizationGO:00346131220.034
female gonad developmentGO:0008585530.034
vasculature developmentGO:0001944700.034
peptidyl serine phosphorylationGO:0018105330.034
protein oligomerizationGO:00512591910.033
amine metabolic processGO:0009308380.033
regulation of intracellular signal transductionGO:19025312180.033
positive regulation of smooth muscle cell migrationGO:0014911270.033
response to amino acidGO:0043200750.033
cellular chemical homeostasisGO:00550822470.033
cellular response to organic cyclic compoundGO:00714072020.033
memoryGO:0007613540.033
intracellular protein transportGO:0006886790.033
cellular amine metabolic processGO:0044106380.032
negative regulation of gene expressionGO:00106291990.032
negative regulation of epithelial cell differentiationGO:003085750.032
cellular response to nitrogen compoundGO:19016992100.032
purine containing compound metabolic processGO:00725212530.032
response to toxic substanceGO:00096361330.031
regulation of nucleic acid templated transcriptionGO:19035063800.031
nucleoside phosphate metabolic processGO:00067532830.031
maintenance of locationGO:0051235170.031
single organism intracellular transportGO:19025821660.031
proteolysisGO:00065081750.031
positive regulation of transcription dna templatedGO:00458931970.031
positive regulation of transferase activityGO:0051347810.030
protein secretionGO:0009306340.030
positive regulation of neuron projection developmentGO:0010976990.030
gamete generationGO:00072761240.030
female pregnancyGO:00075651220.030
peptidyl serine modificationGO:0018209340.030
developmental process involved in reproductionGO:00030061590.030
regulation of cellular amine metabolic processGO:003323880.030
carbohydrate derivative catabolic processGO:19011361470.029
divalent inorganic cation homeostasisGO:00725071650.029
purine ribonucleoside monophosphate catabolic processGO:0009169550.029
single organism behaviorGO:00447081300.029
synapse assemblyGO:0007416290.029
epithelium developmentGO:0060429960.029
cellular lipid metabolic processGO:00442552080.029
nucleotide catabolic processGO:00091661390.029
regulation of transcription dna templatedGO:00063553740.029
ribonucleoside triphosphate metabolic processGO:00091991410.029
negative regulation of actin filament polymerizationGO:003083740.029
response to transition metal nanoparticleGO:19902671220.028
regulation of cell growthGO:0001558850.028
palate developmentGO:006002120.028
purine containing compound catabolic processGO:00725231380.028
protein processingGO:0016485680.028
atp metabolic processGO:0046034720.028
sex differentiationGO:00075481130.028
cellular ketone metabolic processGO:0042180510.028
regulation of cellular amino acid metabolic processGO:000652120.027
blood vessel morphogenesisGO:0048514580.027
negative regulation of cellular protein metabolic processGO:00322691060.027
rhythmic processGO:00485111560.027
positive regulation of growthGO:0045927550.027
cell substrate adhesionGO:0031589290.027
response to external biotic stimulusGO:00432072210.027
axis specificationGO:000979840.027
protein targetingGO:0006605610.027
barbed end actin filament cappingGO:005101610.026
negative regulation of secretion by cellGO:1903531720.026
response to woundingGO:00096112540.026
regulation of vesicle mediated transportGO:0060627810.026
regulation of transferase activityGO:00513381230.026
negative regulation of neuron deathGO:1901215690.026
response to fatty acidGO:0070542650.026
positive regulation of cytoplasmic transportGO:1903651320.026
cellular response to corticosteroid stimulusGO:0071384690.026
endocardial cushion developmentGO:000319710.025
cell junction organizationGO:0034330210.025
brain developmentGO:00074202470.025
developmental growthGO:00485891000.025
actin filament organizationGO:0007015420.025
regulation of signal transductionGO:00099663180.025
positive regulation of protein kinase activityGO:0045860730.025
regulation of growthGO:00400081050.025
protein maturationGO:0051604680.025
nucleoside bisphosphate metabolic processGO:003386510.025
regulation of neurogenesisGO:00507672470.025
response to reactive oxygen speciesGO:00003021200.025
neural crest cell developmentGO:001403220.025
positive regulation of kinase activityGO:0033674770.025
regulation of anatomical structure sizeGO:00900661350.025
negative regulation of cardiac muscle tissue growthGO:005502230.024
response to ionizing radiationGO:0010212590.024
regulation of protein kinase activityGO:00458591050.024
purine nucleotide catabolic processGO:00061951360.024
actin filament depolymerizationGO:003004230.024
negative regulation of cell differentiationGO:0045596990.024
oxoacid metabolic processGO:00434362900.024
actin filament cappingGO:005169320.024
positive regulation of neuron differentiationGO:00456661260.024
response to tumor necrosis factorGO:0034612560.024
regulation of smooth muscle cell proliferationGO:0048660750.024
muscle cell proliferationGO:0033002840.023
regulation of membrane potentialGO:00423911100.023
negative regulation of cell communicationGO:00106481580.023
organ morphogenesisGO:0009887750.023
ovarian follicle developmentGO:0001541310.023
regulation of apoptotic signaling pathwayGO:2001233130.023
cytoplasmic transportGO:00164821150.023
forebrain developmentGO:0030900980.023
smooth muscle cell proliferationGO:0048659770.023
positive regulation of rna biosynthetic processGO:19026801970.023
bone developmentGO:0060348250.023
cell type specific apoptotic processGO:00972851340.022
transforming growth factor beta receptor signaling pathwayGO:0007179180.022
circulatory system developmentGO:00723591340.022
ribonucleoside triphosphate catabolic processGO:00092031220.022
signal releaseGO:00230611450.022
peptide biosynthetic processGO:004304330.022
ovulation cycle processGO:0022602500.021
cell growthGO:00160491040.021
protein polymerizationGO:0051258220.021
regulation of neuron apoptotic processGO:0043523830.021
leukocyte activationGO:0045321760.021
organonitrogen compound catabolic processGO:19015651790.021
positive regulation of rna metabolic processGO:00512542030.021
metal ion homeostasisGO:00550651860.021
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.021
regulation of response to stressGO:00801341260.021
regulation of lipid metabolic processGO:0019216680.021
tissue regenerationGO:0042246360.021
myoblast fusionGO:000752020.021
negative regulation of developmental processGO:00510931250.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.020
positive regulation of developmental growthGO:0048639290.020
regulation of cytoskeleton organizationGO:0051493490.020
ribose phosphate metabolic processGO:00196932350.020
ribonucleoside metabolic processGO:00091191740.020
defense responseGO:00069521940.020
lipid metabolic processGO:00066292830.020
skeletal muscle tissue regenerationGO:0043403100.020
regulation of dendritic spine morphogenesisGO:006100160.020
circulatory system processGO:00030131830.019
bmp signaling pathwayGO:003050940.019
mapk cascadeGO:00001651400.019
dendritic spine morphogenesisGO:006099790.019
regulation of peptide hormone secretionGO:0090276800.019
heart formationGO:006091410.019
regulation of proteolysisGO:0030162660.019
insulin receptor signaling pathwayGO:0008286240.019
regulation of actin filament depolymerizationGO:003083420.019
regulation of cardiac muscle tissue growthGO:0055021120.019
calcium ion homeostasisGO:00550741620.019
regulation of sequence specific dna binding transcription factor activityGO:0051090350.019
positive regulation of cell proliferationGO:00082842490.019
protein importGO:0017038370.018
positive regulation of leukocyte degranulationGO:004330240.018
positive regulation of peptide secretionGO:0002793520.018
cellular calcium ion homeostasisGO:00068741600.018
response to growth factorGO:00708481890.018
positive regulation of intracellular signal transductionGO:19025331380.018
membrane organizationGO:0061024940.018
response to ketoneGO:19016541820.018
regulation of hormone levelsGO:00108171870.018
transmembrane transportGO:00550854120.018
regulation of dna metabolic processGO:0051052600.018
positive regulation of immune system processGO:0002684900.018
urogenital system developmentGO:0001655780.018
metaphase anaphase transition of cell cycleGO:004478410.018
negative regulation of signal transductionGO:0009968830.018
regulation of cell cycleGO:0051726730.017
leukocyte differentiationGO:0002521300.017
negative regulation of growthGO:0045926370.017
positive regulation of retinal cell programmed cell deathGO:004667010.017
valine metabolic processGO:000657310.017
regulation of jak stat cascadeGO:0046425210.017
negative regulation of heart growthGO:006111730.017
negative regulation of actin filament depolymerizationGO:003083520.017
negative regulation of cellular biosynthetic processGO:00313271610.017
ribonucleoside monophosphate catabolic processGO:0009158550.017
pathway restricted smad protein phosphorylationGO:006038910.017
metanephric nephron tubule epithelial cell differentiationGO:007225710.017
cytokinetic processGO:003250610.017
reactive oxygen species biosynthetic processGO:190340980.017
cytokine productionGO:0001816610.017
blood circulationGO:00080151830.017
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.017
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.017
cell part morphogenesisGO:00329901230.017
positive regulation of interleukin 1 secretionGO:005071630.016
negative regulation of secretionGO:0051048820.016

Cast disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.046
disease of cellular proliferationDOID:1456600.046
disease of anatomical entityDOID:700.035
nervous system diseaseDOID:86300.035
central nervous system diseaseDOID:33100.035
organ system cancerDOID:005068600.024