Rattus norvegicus

0 known processes

Dll4

delta-like 4 (Drosophila)

Dll4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of phosphate metabolic processGO:00459372620.125
negative regulation of nitrogen compound metabolic processGO:00511721610.121
negative regulation of cellular metabolic processGO:00313242810.113
rna biosynthetic processGO:00327743800.103
negative regulation of nucleobase containing compound metabolic processGO:00459341530.097
nucleotide metabolic processGO:00091172790.093
carbohydrate derivative metabolic processGO:19011353460.091
nucleoside phosphate metabolic processGO:00067532830.090
negative regulation of metabolic processGO:00098923310.085
regulation of transcription dna templatedGO:00063553740.078
regulation of phosphorus metabolic processGO:00511743490.077
purine containing compound metabolic processGO:00725212530.070
negative regulation of gene expressionGO:00106291990.068
organophosphate metabolic processGO:00196373700.065
negative regulation of macromolecule metabolic processGO:00106052600.062
organelle organizationGO:00069962660.059
Fly
negative regulation of biosynthetic processGO:00098901680.059
regulation of catalytic activityGO:00507903040.058
transcription from rna polymerase ii promoterGO:00063662520.056
single organism organelle organizationGO:19025891800.055
Fly
negative regulation of cellular biosynthetic processGO:00313271610.054
negative regulation of transcription dna templatedGO:00458921160.054
nucleobase containing small molecule metabolic processGO:00550863160.054
single organism biosynthetic processGO:00447113420.052
rna metabolic processGO:00160704060.051
purine nucleotide metabolic processGO:00061632290.051
catabolic processGO:00090563510.049
regulation of molecular functionGO:00650093980.049
regulation of nucleic acid templated transcriptionGO:19035063800.049
regulation of signal transductionGO:00099663180.047
Zebrafish Rat
neuron differentiationGO:00301823680.045
Human Rat
ribose phosphate metabolic processGO:00196932350.044
cellular ketone metabolic processGO:0042180510.044
negative regulation of rna biosynthetic processGO:19026791180.043
positive regulation of cell differentiationGO:00455972170.043
Rat
regulation of rna metabolic processGO:00512523910.042
organic substance catabolic processGO:19015753160.042
cellular catabolic processGO:00442482950.041
nucleic acid templated transcriptionGO:00976593790.041
positive regulation of nitrogen compound metabolic processGO:00511733340.041
lipid metabolic processGO:00066292830.041
nucleobase containing compound catabolic processGO:00346551520.040
secretion by cellGO:00329402480.039
ribonucleotide metabolic processGO:00092592310.039
regulation of cell differentiationGO:00455953200.038
Rat Fly
single organism catabolic processGO:00447122830.038
amine metabolic processGO:0009308380.038
cellular component movementGO:00069282480.038
Human Zebrafish Fly
tissue developmentGO:00098882520.038
Zebrafish Rat Fly
oxoacid metabolic processGO:00434362900.038
purine ribonucleotide metabolic processGO:00091502270.036
macromolecular complex subunit organizationGO:00439333390.036
Fly
cyclic nucleotide metabolic processGO:0009187800.036
cellular amino acid metabolic processGO:00065201070.036
regulation of phosphate metabolic processGO:00192203490.035
transcription dna templatedGO:00063513770.035
regulation of cellular protein metabolic processGO:00322682670.034
cellular component assemblyGO:00226073600.034
negative regulation of apoptotic processGO:00430661810.034
regulation of rna biosynthetic processGO:20011413810.034
organic acid metabolic processGO:00060822920.033
circulatory system developmentGO:00723591340.033
Human Zebrafish
positive regulation of phosphorus metabolic processGO:00105622620.033
regulation of cellular ketone metabolic processGO:0010565270.033
cellular response to stressGO:00335542690.032
cellular amine metabolic processGO:0044106380.032
carboxylic acid metabolic processGO:00197522890.032
cell cell signalingGO:00072673350.032
Fly
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.032
regulation of cd4 positive alpha beta t cell activationGO:200051410.032
positive regulation of nucleic acid templated transcriptionGO:19035081970.031
blood vessel developmentGO:0001568690.031
Human Zebrafish
regulation of cellular component organizationGO:00511283680.031
protein phosphorylationGO:00064683450.031
homeostatic processGO:00425923310.030
carbohydrate metabolic processGO:00059751300.030
intracellular signal transductionGO:00355563140.030
negative regulation of macromolecule biosynthetic processGO:00105581480.030
regulation of cellular amino acid metabolic processGO:000652120.030
negative regulation of nucleic acid templated transcriptionGO:19035071170.029
nucleoside phosphate catabolic processGO:19012921400.029
positive regulation of multicellular organismal processGO:00512403870.029
Rat
organonitrogen compound catabolic processGO:19015651790.029
vesicle mediated transportGO:00161921810.029
response to nutrient levelsGO:00316673700.028
positive regulation of nucleobase containing compound metabolic processGO:00459353190.028
cellular nitrogen compound catabolic processGO:00442701630.028
single organism intracellular transportGO:19025821660.028
programmed cell deathGO:00125013920.027
positive regulation of molecular functionGO:00440932300.027
intracellular transportGO:00469071850.027
positive regulation of catalytic activityGO:00430851840.027
organic cyclic compound catabolic processGO:19013611750.027
regulation of transcription from rna polymerase ii promoterGO:00063572340.026
immune responseGO:00069551040.026
cellular component biogenesisGO:00440853680.026
regulation of cellular catabolic processGO:00313291010.026
cellular response to organic cyclic compoundGO:00714072020.026
heterocycle catabolic processGO:00467001670.025
regulation of purine nucleotide metabolic processGO:19005421150.025
calcium ion homeostasisGO:00550741620.025
actin cytoskeleton organizationGO:0030036730.025
Fly
small gtpase mediated signal transductionGO:0007264360.025
macromolecule localizationGO:00330362520.025
regulation of locomotionGO:00400121480.025
Human Zebrafish
cellular response to endogenous stimulusGO:00714953770.025
Human
single organism carbohydrate metabolic processGO:00447231180.025
regulation of cellular amine metabolic processGO:003323880.024
reproductive processGO:00224143720.024
Rat Fly
carbohydrate derivative biosynthetic processGO:19011371240.024
response to hypoxiaGO:00016662310.024
Rat
ras protein signal transductionGO:0007265290.024
gastrulationGO:000736920.024
response to extracellular stimulusGO:00099913800.024
purine containing compound catabolic processGO:00725231380.024
organophosphate catabolic processGO:00464341480.024
glycosyl compound catabolic processGO:19016581260.023
positive regulation of transcription dna templatedGO:00458931970.023
positive regulation of biosynthetic processGO:00098913190.023
regulation of neuron projection developmentGO:00109751610.023
angiogenesisGO:0001525530.023
Human Zebrafish
positive regulation of cellular amine metabolic processGO:003324030.022
hormone secretionGO:00468791150.022
apoptotic processGO:00069153810.022
aromatic compound catabolic processGO:00194391680.022
regulation of multicellular organismal developmentGO:20000263760.022
Human Zebrafish Rat Fly
purine nucleoside metabolic processGO:00422781690.022
regulation of system processGO:00440572080.022
anatomical structure morphogenesisGO:00096532980.022
Human Zebrafish Fly
regulation of phosphorylationGO:00423252480.022
negative regulation of rna metabolic processGO:00512531230.022
glycosyl compound metabolic processGO:19016571820.022
signal transduction by phosphorylationGO:00230141440.022
positive regulation of cell communicationGO:00106472710.022
localization of cellGO:00516742020.021
Human Zebrafish Fly
actin filament based processGO:0030029860.021
Fly
proteolysisGO:00065081750.021
cellular protein localizationGO:00346131220.021
regulation of apoptotic processGO:00429813350.021
regulation of protein modification processGO:00313991940.021
organonitrogen compound biosynthetic processGO:19015661670.021
reproductionGO:00000032450.021
Rat Fly
positive regulation of response to stimulusGO:00485842850.021
regulation of nucleotide metabolic processGO:00061401170.020
divalent inorganic cation transportGO:00725111340.020
regulation of cellular localizationGO:00603412630.020
response to organophosphorusGO:00466831020.020
positive regulation of rna biosynthetic processGO:19026801970.020
regulation of membrane potentialGO:00423911100.020
cardiovascular system developmentGO:00723581340.020
Human Zebrafish
peptidyl amino acid modificationGO:00181931260.020
neurological system processGO:00508772190.020
positive regulation of cellular component organizationGO:00511302000.020
cellular response to oxygen containing compoundGO:19017013860.020
regulation of protein phosphorylationGO:00019321830.020
organophosphate biosynthetic processGO:00904071430.019
response to inorganic substanceGO:00100353770.019
protein localizationGO:00081041910.019
positive regulation of phosphorylationGO:00423271770.019
regulation of canonical wnt signaling pathwayGO:006082840.019
lymphocyte activationGO:0046649430.019
neuron developmentGO:00486662860.019
negative regulation of molecular functionGO:00440921330.019
positive regulation of purine nucleotide metabolic processGO:1900544910.019
regulation of anatomical structure morphogenesisGO:00226031410.019
Human Zebrafish
regulation of organelle organizationGO:0033043800.019
cell adhesionGO:00071551100.018
positive regulation of cellular amino acid metabolic processGO:004576410.018
purine nucleoside catabolic processGO:00061521240.018
ribonucleoside metabolic processGO:00091191740.018
response to monosaccharideGO:00342841590.018
positive regulation of cellular biosynthetic processGO:00313282950.018
immune system processGO:00023762040.018
positive regulation of cytosolic calcium ion concentrationGO:00072041220.018
hormone transportGO:00099141210.018
nucleotide catabolic processGO:00091661390.018
purine ribonucleotide catabolic processGO:00091541360.018
cytoskeleton organizationGO:00070101110.018
Fly
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.018
axis specificationGO:000979840.017
positive regulation of macromolecule biosynthetic processGO:00105572470.017
regulation of programmed cell deathGO:00430673410.017
nucleoside triphosphate metabolic processGO:00091411440.017
nucleoside metabolic processGO:00091161790.017
regulation of regulatory t cell differentiationGO:004558920.017
cytoplasmic transportGO:00164821150.017
heart morphogenesisGO:000300730.017
cellular homeostasisGO:00197252520.017
g protein coupled receptor signaling pathwayGO:00071862420.017
nucleotide biosynthetic processGO:0009165980.017
cation transportGO:00068123820.017
oxidation reduction processGO:00551143040.017
regulation of stem cell differentiationGO:200073620.017
negative regulation of programmed cell deathGO:00430691830.017
nucleoside catabolic processGO:00091641260.017
purine nucleotide biosynthetic processGO:0006164830.017
single organism behaviorGO:00447081300.017
cellular lipid metabolic processGO:00442552080.017
cell projection organizationGO:00300303020.017
inflammatory responseGO:00069541500.017
alcohol metabolic processGO:0006066770.016
positive regulation of transportGO:00510502450.016
ion transmembrane transportGO:00342203650.016
purine ribonucleoside catabolic processGO:00461301240.016
regulation of neuron differentiationGO:00456642080.016
regulation of cell projection organizationGO:00313441750.016
regulation of cell motilityGO:20001451310.016
Human Zebrafish
regulation of neurogenesisGO:00507672470.016
Rat Fly
intracellular protein transportGO:0006886790.016
purine nucleoside triphosphate catabolic processGO:00091461220.016
ribonucleoside triphosphate catabolic processGO:00092031220.016
negative regulation of signalingGO:00230571570.016
Rat
regulation of purine nucleotide catabolic processGO:0033121650.016
regulation of hydrolase activityGO:00513361430.015
neuron projection developmentGO:00311752730.015
cation homeostasisGO:00550801950.015
membrane organizationGO:0061024940.015
mrna transcription from rna polymerase ii promoterGO:004278910.015
positive regulation of gene expressionGO:00106282440.015
rho protein signal transductionGO:0007266110.015
carbohydrate derivative catabolic processGO:19011361470.015
cell projection morphogenesisGO:00488581230.015
single organism reproductive processGO:00447022970.015
Rat Fly
brain developmentGO:00074202470.015
Rat
defense responseGO:00069521940.015
positive regulation of developmental processGO:00510942830.015
Rat
regulation of actin filament based processGO:0032970420.015
guanosine containing compound metabolic processGO:1901068740.015
protein complex subunit organizationGO:00718223020.015
Fly
central nervous system developmentGO:00074173110.015
Human Rat
vascular process in circulatory systemGO:0003018960.015
vasculature developmentGO:0001944700.015
Human Zebrafish
protein autophosphorylationGO:0046777660.015
single organism cellular localizationGO:19025801020.015
positive regulation of immune system processGO:0002684900.015
secretionGO:00469033070.015
guanosine containing compound catabolic processGO:1901069710.015
positive regulation of nucleoside metabolic processGO:0045979550.015
purine ribonucleoside metabolic processGO:00461281680.014
response to glucocorticoidGO:00513842230.014
positive regulation of rna metabolic processGO:00512542030.014
neuron projection morphogenesisGO:00488121220.014
response to purine containing compoundGO:00140741260.014
calcium ion transportGO:00068161310.014
divalent metal ion transportGO:00708381320.014
skeletal system developmentGO:0001501410.014
ribose phosphate biosynthetic processGO:0046390870.014
metal ion transportGO:00300012890.014
regulation of cellular component movementGO:00512701500.014
Human Zebrafish
response to starvationGO:0042594590.014
purine nucleotide catabolic processGO:00061951360.014
cellular macromolecule localizationGO:00707271220.014
positive regulation of cellular catabolic processGO:0031331710.014
cellular component morphogenesisGO:00329891550.014
Fly
multicellular organism growthGO:003526410.014
response to estrogenGO:00436272320.014
synaptic transmissionGO:00072682350.014
nitrogen compound transportGO:00717052290.014
positive regulation of nervous system developmentGO:00519621780.013
Rat
regulation of catabolic processGO:00098941130.013
ribonucleoside catabolic processGO:00424541260.013
regulation of secretion by cellGO:19035302080.013
signal releaseGO:00230611450.013
regulation of anatomical structure sizeGO:00900661350.013
response to oxidative stressGO:00069791860.013
formation of primary germ layerGO:000170410.013
response to decreased oxygen levelsGO:00362932370.013
Rat
regulation of peptide secretionGO:0002791820.013
response to metal ionGO:00100382530.013
regulation of nucleoside metabolic processGO:0009118660.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
adult locomotory behaviorGO:000834440.013
positive regulation of humoral immune responseGO:000292220.013
gtp metabolic processGO:0046039720.013
positive regulation of hydrolase activityGO:0051345860.013
response to carbohydrateGO:00097431830.013
behaviorGO:00076102050.013
response to hexoseGO:00097461440.013
leukocyte activationGO:0045321760.013
positive regulation of cell developmentGO:00107201760.013
Rat
regulation of transferase activityGO:00513381230.013
chemical homeostasisGO:00488782920.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
cellular cation homeostasisGO:00300031800.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
positive regulation of cellular protein metabolic processGO:00322701670.013
regulation of protein metabolic processGO:00512462890.013
ribonucleotide catabolic processGO:00092611360.013
cell morphogenesis involved in differentiationGO:00009041190.013
Fly
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
cellular response to glucocorticoid stimulusGO:0071385680.013
mesoderm developmentGO:000749820.013
Fly
cellular response to hormone stimulusGO:00328702470.013
cellular divalent inorganic cation homeostasisGO:00725031620.012
negative regulation of cell communicationGO:00106481580.012
Rat
renal system developmentGO:0072001670.012
cellular response to growth factor stimulusGO:00713631620.012
Human Zebrafish
regulation of intracellular signal transductionGO:19025312180.012
positive regulation of apoptotic processGO:00430651540.012
circulatory system processGO:00030131830.012
morphogenesis of embryonic epitheliumGO:001633130.012
positive regulation of programmed cell deathGO:00430681570.012
negative regulation of cellular protein metabolic processGO:00322691060.012
regulation of ion transportGO:00432692450.012
positive regulation of rho gtpase activityGO:0032321130.012
multi multicellular organism processGO:00447061380.012
positive regulation of neurogenesisGO:00507691650.012
Rat
tube formationGO:003514830.012
response to corticosteroidGO:00319602350.012
multi organism reproductive processGO:00447032620.012
Rat Fly
actin filament organizationGO:0007015420.012
Fly
positive regulation of protein metabolic processGO:00512471780.012
negative regulation of multicellular organismal processGO:00512412030.012
Human Zebrafish Rat Fly
cellular metal ion homeostasisGO:00068751720.012
sex differentiationGO:00075481130.012
Rat
hexose metabolic processGO:0019318580.012
cellular response to nitrogen compoundGO:19016992100.012
organic hydroxy compound metabolic processGO:19016151150.012
regulation of nucleotide catabolic processGO:0030811650.012
negative regulation of innate immune responseGO:004582440.012
cellular carbohydrate metabolic processGO:0044262720.012
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.012
negative regulation of catalytic activityGO:00430861030.012
head developmentGO:00603222470.012
Rat
response to nutrientGO:00075842480.012
purine containing compound biosynthetic processGO:0072522850.012
purine ribonucleoside triphosphate metabolic processGO:00092051400.012
regulation of cell proliferationGO:00421273590.012
Human Rat Fly
cellular response to corticosteroid stimulusGO:0071384690.012
cellular response to lipidGO:00713962010.012
cellular chemical homeostasisGO:00550822470.012
regulation of kinase activityGO:00435491170.012
regulation of neurological system processGO:0031644430.011
cell migrationGO:00164771970.011
Human Zebrafish Fly
sexual reproductionGO:00199531480.011
Rat Fly
blood circulationGO:00080151830.011
regulation of secretionGO:00510462240.011
multicellular organismal reproductive processGO:00486092330.011
Rat Fly
cellular ion homeostasisGO:00068731840.011
lipid storageGO:001991510.011
response to reactive oxygen speciesGO:00003021200.011
positive regulation of signalingGO:00230562700.011
positive regulation of neuron differentiationGO:00456661260.011
response to transition metal nanoparticleGO:19902671220.011
response to oxygen levelsGO:00704822650.011
Rat
response to peptideGO:19016522920.011
positive regulation of mapk cascadeGO:0043410920.011
regulation of natural killer cell mediated immune response to tumor cellGO:000285510.011
female pregnancyGO:00075651220.011
protein complex biogenesisGO:00702712630.011
regulation of hormone levelsGO:00108171870.011
gamete generationGO:00072761240.011
Rat Fly
positive regulation of protein modification processGO:00314011420.011
salivary gland developmentGO:000743130.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
Fly
regulation of peptide hormone secretionGO:0090276800.011
gtp catabolic processGO:0006184710.011
divalent inorganic cation homeostasisGO:00725071650.011
exocytosisGO:0006887600.011
erythrocyte differentiationGO:003021810.011
reactive oxygen species metabolic processGO:0072593370.011
second messenger mediated signalingGO:0019932510.011
cellular response to organonitrogen compoundGO:00714171970.011
negative regulation of transportGO:00510511360.011
alpha beta t cell differentiationGO:004663220.011
biological adhesionGO:00226101100.011
salivary gland morphogenesisGO:000743510.011
regulation of hormone secretionGO:00468831060.010
peptide secretionGO:0002790860.010
response to vitaminGO:00332731310.010
single organism membrane organizationGO:0044802740.010
regulation of response to stressGO:00801341260.010
spindle organizationGO:000705120.010
b cell mediated immunityGO:001972440.010
regulation of cell developmentGO:00602842630.010
Rat Fly
regulation of proteasomal protein catabolic processGO:006113640.010
hematopoietic progenitor cell differentiationGO:000224420.010
positive regulation of cell deathGO:00109421840.010
positive regulation of regulatory t cell differentiationGO:004559120.010
response to ketoneGO:19016541820.010
ion homeostasisGO:00508012120.010
alpha beta t cell activationGO:004663130.010
negative regulation of protein metabolic processGO:00512481140.010
cd4 positive alpha beta t cell activationGO:003571010.010
regulation of interferon gamma productionGO:003264930.010
positive regulation of nucleotide metabolic processGO:0045981910.010
muscle cell proliferationGO:0033002840.010

Dll4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.016
disease of metabolismDOID:001466700.014
nervous system diseaseDOID:86300.013
disease of anatomical entityDOID:700.013
inherited metabolic disorderDOID:65500.011
central nervous system diseaseDOID:33100.011