Rattus norvegicus

0 known processes

Actn2

actinin alpha 2

Actn2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
actin myosin filament slidingGO:003327520.654
cardiac ventricle developmentGO:000323110.615
muscle filament slidingGO:003004920.465
striated muscle contractionGO:0006941440.423
cardiac muscle tissue morphogenesisGO:005500810.322
aromatic compound catabolic processGO:00194391680.255
single organism organelle organizationGO:19025891800.245
muscle contractionGO:0006936880.236
Mouse
cardiac muscle contractionGO:0060048270.234
organic substance catabolic processGO:19015753160.219
nucleoside triphosphate metabolic processGO:00091411440.214
cellular component biogenesisGO:00440853680.213
Human
heart contractionGO:0060047570.197
nucleobase containing small molecule metabolic processGO:00550863160.196
heart morphogenesisGO:000300730.194
cardiac chamber developmentGO:000320510.187
ribonucleotide metabolic processGO:00092592310.184
nucleoside phosphate metabolic processGO:00067532830.172
purine nucleoside triphosphate catabolic processGO:00091461220.170
carbohydrate derivative metabolic processGO:19011353460.164
cellular catabolic processGO:00442482950.164
organophosphate metabolic processGO:00196373700.161
nucleoside catabolic processGO:00091641260.159
cytoskeleton organizationGO:00070101110.159
blood circulationGO:00080151830.159
cellular component assemblyGO:00226073600.156
Human
glycosyl compound metabolic processGO:19016571820.148
purine nucleoside monophosphate catabolic processGO:0009128550.142
purine containing compound metabolic processGO:00725212530.139
nucleoside monophosphate metabolic processGO:0009123930.139
carbohydrate derivative catabolic processGO:19011361470.138
nucleoside metabolic processGO:00091161790.137
slow twitch skeletal muscle fiber contractionGO:003144420.136
twitch skeletal muscle contractionGO:001472130.135
catabolic processGO:00090563510.132
anatomical structure morphogenesisGO:00096532980.131
cellular nitrogen compound catabolic processGO:00442701630.127
organophosphate catabolic processGO:00464341480.127
organelle organizationGO:00069962660.126
purine nucleotide catabolic processGO:00061951360.122
glycosyl compound catabolic processGO:19016581260.121
organonitrogen compound catabolic processGO:19015651790.120
purine ribonucleoside triphosphate metabolic processGO:00092051400.118
regulation of system processGO:00440572080.117
purine ribonucleoside triphosphate catabolic processGO:00092071220.114
purine ribonucleoside monophosphate metabolic processGO:0009167840.113
nucleoside triphosphate catabolic processGO:00091431230.112
nucleotide metabolic processGO:00091172790.110
ribonucleoside triphosphate metabolic processGO:00091991410.109
ribonucleoside metabolic processGO:00091191740.109
nucleoside phosphate catabolic processGO:19012921400.106
purine ribonucleoside monophosphate catabolic processGO:0009169550.106
macromolecular complex subunit organizationGO:00439333390.106
Human
circulatory system processGO:00030131830.105
actin filament based processGO:0030029860.105
circulatory system developmentGO:00723591340.105
purine ribonucleoside metabolic processGO:00461281680.103
purine nucleoside catabolic processGO:00061521240.101
actin mediated cell contractionGO:0070252120.099
cellular component morphogenesisGO:00329891550.099
actin filament based movementGO:0030048160.097
ribonucleoside catabolic processGO:00424541260.096
purine nucleoside triphosphate metabolic processGO:00091441410.095
purine nucleoside monophosphate metabolic processGO:0009126840.095
ribonucleotide catabolic processGO:00092611360.095
nucleobase containing compound catabolic processGO:00346551520.095
muscle system processGO:00030121150.094
Mouse
tissue developmentGO:00098882520.092
ribose phosphate metabolic processGO:00196932350.092
purine nucleotide metabolic processGO:00061632290.091
heart processGO:0003015570.091
cellular component movementGO:00069282480.091
purine nucleoside metabolic processGO:00422781690.088
purine containing compound catabolic processGO:00725231380.088
regulation of muscle system processGO:0090257790.083
myosin filament assemblyGO:003103410.082
response to hypoxiaGO:00016662310.081
nucleotide catabolic processGO:00091661390.081
purine ribonucleoside catabolic processGO:00461301240.081
rna metabolic processGO:00160704060.076
Mouse
ribonucleoside triphosphate catabolic processGO:00092031220.075
regulation of cellular component organizationGO:00511283680.075
protein complex subunit organizationGO:00718223020.075
Human
muscle tissue morphogenesisGO:006041510.074
regulation of phosphate metabolic processGO:00192203490.071
macromolecular complex assemblyGO:00650032730.071
Human
muscle organ morphogenesisGO:004864410.071
purine ribonucleotide metabolic processGO:00091502270.070
neuron differentiationGO:00301823680.068
protein complex biogenesisGO:00702712630.067
Human
response to decreased oxygen levelsGO:00362932370.066
cell morphogenesis involved in neuron differentiationGO:00486671060.065
ribonucleoside monophosphate metabolic processGO:0009161880.063
anatomical structure formation involved in morphogenesisGO:0048646830.062
atp metabolic processGO:0046034720.061
intracellular signal transductionGO:00355563140.061
regulation of muscle contractionGO:0006937530.061
cellular chemical homeostasisGO:00550822470.060
organic cyclic compound catabolic processGO:19013611750.058
regulation of molecular functionGO:00650093980.057
Human Mouse
atp catabolic processGO:0006200540.056
heart developmentGO:0007507720.055
muscle tissue developmentGO:0060537580.054
actin cytoskeleton organizationGO:0030036730.053
voluntary skeletal muscle contractionGO:000301030.053
cellular response to oxygen containing compoundGO:19017013860.053
cell projection organizationGO:00300303020.052
Human
response to extracellular stimulusGO:00099913800.051
regulation of blood circulationGO:19035221100.051
nucleoside monophosphate catabolic processGO:0009125560.050
regulation of programmed cell deathGO:00430673410.049
carboxylic acid metabolic processGO:00197522890.049
heterocycle catabolic processGO:00467001670.049
regulation of purine nucleotide metabolic processGO:19005421150.048
cardiac myofibril assemblyGO:005500310.047
response to metal ionGO:00100382530.046
organ morphogenesisGO:0009887750.045
single organism catabolic processGO:00447122830.044
metal ion homeostasisGO:00550651860.044
response to oxygen levelsGO:00704822650.044
cellular response to stressGO:00335542690.043
muscle structure developmentGO:0061061870.042
cardiovascular system developmentGO:00723581340.040
regulation of phosphorus metabolic processGO:00511743490.040
calcium ion homeostasisGO:00550741620.039
response to inorganic substanceGO:00100353770.039
response to reactive oxygen speciesGO:00003021200.039
cell morphogenesis involved in differentiationGO:00009041190.037
positive regulation of nitrogen compound metabolic processGO:00511733340.037
homeostatic processGO:00425923310.037
striated muscle tissue developmentGO:0014706580.036
programmed cell deathGO:00125013920.036
myosin filament organizationGO:003103320.035
regulation of cellular catabolic processGO:00313291010.035
regulation of cellular localizationGO:00603412630.035
Human
cellular amino acid metabolic processGO:00065201070.034
regulation of apoptotic processGO:00429813350.033
response to mechanical stimulusGO:00096121340.033
nucleic acid templated transcriptionGO:00976593790.033
Mouse
cellular divalent inorganic cation homeostasisGO:00725031620.033
oxidation reduction processGO:00551143040.033
regulation of purine nucleotide catabolic processGO:0033121650.032
cation homeostasisGO:00550801950.032
protein complex assemblyGO:00064612630.032
Human
regulation of cell growthGO:0001558850.032
cell growthGO:00160491040.032
response to nutrientGO:00075842480.032
regulation of heart contractionGO:0008016480.031
organic acid metabolic processGO:00060822920.031
protein localizationGO:00081041910.031
Human
regulation of striated muscle contractionGO:0006942210.031
actin filament organizationGO:0007015420.031
purine ribonucleotide catabolic processGO:00091541360.031
cellular protein complex assemblyGO:0043623440.031
tissue morphogenesisGO:0048729220.030
response to purine containing compoundGO:00140741260.030
oxoacid metabolic processGO:00434362900.030
growthGO:00400071650.030
axonogenesisGO:0007409710.030
neuron projection morphogenesisGO:00488121220.030
negative regulation of cell deathGO:00605482290.030
cell projection morphogenesisGO:00488581230.029
response to oxidative stressGO:00069791860.029
positive regulation of biosynthetic processGO:00098913190.029
positive regulation of cell communicationGO:00106472710.029
regulation of neuron projection developmentGO:00109751610.029
muscle organ developmentGO:0007517500.029
cellular amino acid biosynthetic processGO:0008652320.029
skeletal muscle contractionGO:0003009170.028
response to heatGO:0009408600.028
cardiac muscle cell developmentGO:0055013160.028
musculoskeletal movementGO:0050881170.028
regulation of rna biosynthetic processGO:20011413810.027
Mouse
neuron projection developmentGO:00311752730.027
locomotionGO:00400112370.027
organophosphate biosynthetic processGO:00904071430.027
cellular component assembly involved in morphogenesisGO:0010927170.027
regulation of establishment of planar polarityGO:009017520.027
cellular homeostasisGO:00197252520.027
regulation of multicellular organismal developmentGO:20000263760.027
regulation of nervous system developmentGO:00519602640.026
reproductionGO:00000032450.026
ribonucleoside monophosphate catabolic processGO:0009158550.026
cell cell signalingGO:00072673350.026
ion transmembrane transportGO:00342203650.026
Human
actomyosin structure organizationGO:0031032220.026
response to nutrient levelsGO:00316673700.026
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.026
organelle assemblyGO:0070925220.026
cellular protein localizationGO:00346131220.025
Human
multicellular organismal movementGO:0050879170.025
single organism biosynthetic processGO:00447113420.025
transcription dna templatedGO:00063513770.025
protein localization to organelleGO:0033365570.025
chemosensory behaviorGO:000763520.025
regulation of rna metabolic processGO:00512523910.025
Mouse
regulation of cellular amine metabolic processGO:003323880.025
cellular calcium ion homeostasisGO:00068741600.025
macromolecule localizationGO:00330362520.025
Human
regulation of nucleotide catabolic processGO:0030811650.025
regulation of cellular component movementGO:00512701500.025
cell morphogenesisGO:00009021420.025
axon developmentGO:0061564960.025
positive regulation of multicellular organismal processGO:00512403870.024
apoptotic processGO:00069153810.024
chemical homeostasisGO:00488782920.024
ion homeostasisGO:00508012120.024
cellular amine metabolic processGO:0044106380.024
cellular macromolecule localizationGO:00707271220.024
Human
amine metabolic processGO:0009308380.024
regulation of signal transductionGO:00099663180.023
Mouse
divalent inorganic cation homeostasisGO:00725071650.023
regulation of phosphorylationGO:00423252480.023
respiratory system processGO:000301630.023
regulation of nucleotide metabolic processGO:00061401170.023
central nervous system developmentGO:00074173110.023
cellular response to organonitrogen compoundGO:00714171970.023
regulation of neuron differentiationGO:00456642080.023
negative regulation of cellular metabolic processGO:00313242810.023
striated muscle cell developmentGO:0055002260.023
regulation of catabolic processGO:00098941130.023
negative regulation of metabolic processGO:00098923310.023
nitrogen compound transportGO:00717052290.022
positive regulation of gene expressionGO:00106282440.022
cellular response to nitrogen compoundGO:19016992100.022
response to peptideGO:19016522920.022
negative regulation of apoptotic processGO:00430661810.022
regulation of proteasomal protein catabolic processGO:006113640.022
cardiocyte differentiationGO:0035051220.022
cognitionGO:0050890920.021
cellular ketone metabolic processGO:0042180510.021
multicellular organismal reproductive processGO:00486092330.021
cell part morphogenesisGO:00329901230.021
positive regulation of molecular functionGO:00440932300.021
Human Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353190.021
sexual reproductionGO:00199531480.021
positive regulation of phosphorus metabolic processGO:00105622620.021
cellular cation homeostasisGO:00300031800.021
regulation of cell morphogenesisGO:0022604770.020
cellular metal ion homeostasisGO:00068751720.020
neuron developmentGO:00486662860.020
defense responseGO:00069521940.020
regulation of catalytic activityGO:00507903040.020
rna biosynthetic processGO:00327743800.020
Mouse
behaviorGO:00076102050.019
response to insulinGO:00328681330.019
dendrite morphogenesisGO:0048813430.019
cellular ion homeostasisGO:00068731840.019
cellular response to insulin stimulusGO:0032869810.019
response to glucocorticoidGO:00513842230.019
positive regulation of cellular component organizationGO:00511302000.019
multi organism reproductive processGO:00447032620.019
gastrulationGO:000736920.019
response to woundingGO:00096112540.019
regulation of atpase activityGO:004346270.018
regulation of cell morphogenesis involved in differentiationGO:0010769720.018
response to temperature stimulusGO:0009266940.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
negative regulation of gene expressionGO:00106291990.018
anion transportGO:00068201780.018
respiratory gaseous exchangeGO:000758540.018
vesicle mediated transportGO:00161921810.018
regulation of neurogenesisGO:00507672470.018
secretionGO:00469033070.018
regulation of cellular amino acid metabolic processGO:000652120.018
response to ethanolGO:00454711620.018
regulation of hydrolase activityGO:00513361430.018
intracellular transportGO:00469071850.018
regulation of cellular ketone metabolic processGO:0010565270.018
regulation of growthGO:00400081050.017
organic anion transportGO:00157111320.017
response to peptide hormoneGO:00434342780.017
energy derivation by oxidation of organic compoundsGO:0015980460.017
positive regulation of signalingGO:00230562700.017
cellular macromolecular complex assemblyGO:0034622580.017
brain developmentGO:00074202470.017
cellular response to endogenous stimulusGO:00714953770.017
skeletal muscle organ developmentGO:0060538330.017
regulation of ion transportGO:00432692450.017
Human
positive regulation of cell proliferationGO:00082842490.017
synaptic transmissionGO:00072682350.017
cardiac cell developmentGO:0055006160.017
regulation of anatomical structure morphogenesisGO:00226031410.017
positive regulation of phosphate metabolic processGO:00459372620.017
muscle cell developmentGO:0055001260.016
response to other organismGO:00517072200.016
regulation of cell developmentGO:00602842630.016
secretion by cellGO:00329402480.016
sarcomere organizationGO:004521460.016
reproductive processGO:00224143720.016
hormone transportGO:00099141210.016
signal releaseGO:00230611450.016
cold acclimationGO:000963110.016
head developmentGO:00603222470.016
regulation of transcription dna templatedGO:00063553740.016
positive regulation of programmed cell deathGO:00430681570.016
regulation of nucleic acid templated transcriptionGO:19035063800.016
Mouse
negative regulation of macromolecule metabolic processGO:00106052600.016
positive regulation of neurogenesisGO:00507691650.016
cellular response to hormone stimulusGO:00328702470.015
regulation of anatomical structure sizeGO:00900661350.015
ventricular cardiac muscle cell action potentialGO:008600520.015
negative regulation of cell communicationGO:00106481580.015
regulation of cell differentiationGO:00455953200.015
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.015
regulation of dendrite developmentGO:0050773590.015
carbohydrate derivative biosynthetic processGO:19011371240.015
carbohydrate catabolic processGO:0016052400.015
negative regulation of programmed cell deathGO:00430691830.015
protein phosphorylationGO:00064683450.015
cardiac conductionGO:006133720.015
regulation of organelle organizationGO:0033043800.015
proteolysisGO:00065081750.015
response to hydrogen peroxideGO:0042542890.015
positive regulation of cellular biosynthetic processGO:00313282950.015
sequestering of calcium ionGO:005120880.015
positive regulation of cellular catabolic processGO:0031331710.015
cellular response to organic cyclic compoundGO:00714072020.015
positive regulation of apoptotic processGO:00430651540.015
regulation of nucleoside metabolic processGO:0009118660.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
carboxylic acid transportGO:00469421150.014
regulation of cardiac muscle contractionGO:0055117170.014
negative regulation of cell differentiationGO:0045596990.014
negative regulation of multicellular organismal processGO:00512412030.014
acrosome assemblyGO:000167530.014
negative regulation of signalingGO:00230571570.014
positive regulation of signal transductionGO:00099671750.014
negative regulation of growthGO:0045926370.014
posttranscriptional regulation of gene expressionGO:0010608370.014
response to biotic stimulusGO:00096072260.014
positive regulation of cellular protein metabolic processGO:00322701670.014
diaphragm contractionGO:000208620.014
membrane organizationGO:0061024940.014
glucose metabolic processGO:0006006520.014
membrane depolarization during action potentialGO:008601010.014
regulation of cellular protein metabolic processGO:00322682670.014
epithelium developmentGO:0060429960.014
regulation of cytoskeleton organizationGO:0051493490.014
single organism intracellular transportGO:19025821660.014
cellular response to abiotic stimulusGO:0071214850.014
carbohydrate metabolic processGO:00059751300.014
peptide transportGO:0015833970.014
divalent inorganic cation transportGO:00725111340.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
regulation of protein modification processGO:00313991940.013
regulation of cell projection organizationGO:00313441750.013
male gamete generationGO:0048232990.013
rna localizationGO:000640340.013
gliogenesisGO:0042063930.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
dendrite developmentGO:0016358720.013
ribose phosphate biosynthetic processGO:0046390870.013
establishment of tissue polarityGO:000716420.013
negative regulation of developmental processGO:00510931250.013
regulation of hormone levelsGO:00108171870.013
positive regulation of lipid catabolic processGO:005099640.013
regulation of atp catabolic processGO:190328970.013
positive regulation of cellular amine metabolic processGO:003324030.013
response to acid chemicalGO:00011012220.013
positive regulation of cell deathGO:00109421840.013
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.013
neuromuscular processGO:005090520.013
agingGO:00075682410.013
hormone secretionGO:00468791150.013
small gtpase mediated signal transductionGO:0007264360.013
developmental growthGO:00485891000.013
regulation of locomotionGO:00400121480.013
positive regulation of long term synaptic potentiationGO:190027340.013
axis specificationGO:000979840.012
monocarboxylic acid metabolic processGO:00327871520.012
single organism reproductive processGO:00447022970.012
positive regulation of developmental processGO:00510942830.012
regulation of protein metabolic processGO:00512462890.012
insulin secretionGO:0030073690.012
response to growth factorGO:00708481890.012
response to calcium ionGO:0051592590.012
generation of precursor metabolites and energyGO:0006091620.012
regulation of hormone secretionGO:00468831060.012
gamete generationGO:00072761240.012
response to alkaloidGO:00432791320.012
organonitrogen compound biosynthetic processGO:19015661670.012
negative regulation of nervous system developmentGO:0051961790.012
regulation of actin filament based processGO:0032970420.012
negative regulation of cellular component organizationGO:0051129830.012
cellular response to peptideGO:19016531330.012
tissue remodelingGO:0048771400.012
regulation of insulin secretionGO:0050796650.012
involuntary skeletal muscle contractionGO:000301120.012
regulation of intracellular signal transductionGO:19025312180.012
nucleotide biosynthetic processGO:0009165980.012
single organism behaviorGO:00447081300.012
signal transduction by phosphorylationGO:00230141440.012
endomembrane system organizationGO:0010256480.012
regulation of cell proliferationGO:00421273590.011
regulation of secretionGO:00510462240.011
muscle cell differentiationGO:0042692520.011
dna metabolic processGO:0006259960.011
establishment of planar polarityGO:000173610.011
metal ion transportGO:00300012890.011
Human
spermatogenesisGO:0007283990.011
neurological system processGO:00508772190.011
organic hydroxy compound metabolic processGO:19016151150.011
positive regulation of nucleotide metabolic processGO:0045981910.011
positive regulation of rna biosynthetic processGO:19026801970.011
learning or memoryGO:0007611900.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
single organism carbohydrate catabolic processGO:0044724400.011
positive regulation of phosphorylationGO:00423271770.011
bmp signaling pathwayGO:003050940.011
positive regulation of cytoskeleton organizationGO:0051495260.011
dephosphorylationGO:0016311980.011
organic acid catabolic processGO:0016054490.011
purine containing compound biosynthetic processGO:0072522850.011
protein homooligomerizationGO:0051260910.011
Human
negative regulation of transportGO:00510511360.011
Human
positive regulation of cell differentiationGO:00455972170.011
positive regulation of response to stimulusGO:00485842850.011
carboxylic acid catabolic processGO:0046395490.011
regulation of cellular component biogenesisGO:0044087860.011
ras protein signal transductionGO:0007265290.011
mapk cascadeGO:00001651400.011
chromosome segregationGO:000705920.011
multicellular organism reproductionGO:00325042330.011
regulation of mapk cascadeGO:00434081160.011
organic acid biosynthetic processGO:0016053830.011
cation transportGO:00068123820.011
Human
positive regulation of transcription dna templatedGO:00458931970.011
cardiac muscle tissue developmentGO:0048738260.011
regulation of membrane potentialGO:00423911100.011
Human
single organism carbohydrate metabolic processGO:00447231180.011
regulation of ion transmembrane transportGO:00347651210.011
Human
regulation of reactive oxygen species metabolic processGO:2000377260.011
olfactory behaviorGO:004204820.011
glucan metabolic processGO:0044042230.010
regulation of actin filament based movementGO:1903115120.010
spindle organizationGO:000705120.010
negative regulation of response to stimulusGO:00485851550.010
camera type eye developmentGO:0043010480.010
regulation of canonical wnt signaling pathwayGO:006082840.010
skeletal muscle tissue developmentGO:0007519310.010
positive regulation of protein modification processGO:00314011420.010
hexose metabolic processGO:0019318580.010
response to fatty acidGO:0070542650.010
reactive oxygen species metabolic processGO:0072593370.010
myofibril assemblyGO:003023960.010
negative regulation of cell growthGO:0030308330.010
protein oligomerizationGO:00512591910.010
Human
nucleoside phosphate biosynthetic processGO:19012931020.010
actin crosslink formationGO:005176430.010

Actn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.972
disease of anatomical entityDOID:700.972
heart diseaseDOID:11400.972
muscular diseaseDOID:008000000.972
intrinsic cardiomyopathyDOID:006003600.972
cardiomyopathyDOID:005070000.972
myopathyDOID:42300.972
cardiovascular system diseaseDOID:128700.972
muscle tissue diseaseDOID:6600.972
hypertrophic cardiomyopathyDOID:1198400.902
dilated cardiomyopathyDOID:1293000.743
muscular dystrophyDOID:988400.257
inherited metabolic disorderDOID:65500.030
disease of metabolismDOID:001466700.030
carbohydrate metabolic disorderDOID:297800.026
nervous system diseaseDOID:86300.021
congenital heart diseaseDOID:168200.013
heart septal defectDOID:168100.013
central nervous system diseaseDOID:33100.010