Rattus norvegicus

70 known processes

Kcnma1

potassium large conductance calcium-activated channel, subfamily M, alpha member 1

(Aliases: Slo,Kcnma,KCNMA1b,KCNMA1c)

Kcnma1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
intracellular signal transductionGO:00355563140.171
positive regulation of response to stimulusGO:00485842850.165
regulation of signal transductionGO:00099663180.154
regulation of molecular functionGO:00650093980.154
positive regulation of multicellular organismal processGO:00512403870.133
oxoacid metabolic processGO:00434362900.117
macromolecular complex subunit organizationGO:00439333390.116
response to monosaccharideGO:00342841590.100
regulation of phosphate metabolic processGO:00192203490.099
response to external biotic stimulusGO:00432072210.096
cell cell signalingGO:00072673350.093
Mouse
protein complex assemblyGO:00064612630.091
positive regulation of gene expressionGO:00106282440.089
apoptotic processGO:00069153810.088
Human
response to growth factorGO:00708481890.084
protein complex biogenesisGO:00702712630.084
neuron developmentGO:00486662860.082
axon developmentGO:0061564960.081
carboxylic acid metabolic processGO:00197522890.077
positive regulation of signal transductionGO:00099671750.076
protein phosphorylationGO:00064683450.076
homeostatic processGO:00425923310.070
Human Mouse
metal ion transportGO:00300012890.069
regulation of phosphorus metabolic processGO:00511743490.068
anatomical structure morphogenesisGO:00096532980.066
response to carbohydrateGO:00097431830.066
carbohydrate derivative metabolic processGO:19011353460.065
regulation of catalytic activityGO:00507903040.064
response to hexoseGO:00097461440.063
cell migrationGO:00164771970.062
inorganic ion transmembrane transportGO:00986602290.061
positive regulation of biosynthetic processGO:00098913190.061
catabolic processGO:00090563510.059
regulation of response to stressGO:00801341260.059
multicellular organism reproductionGO:00325042330.058
cellular response to stressGO:00335542690.058
cellular component biogenesisGO:00440853680.057
positive regulation of nucleobase containing compound metabolic processGO:00459353190.057
rna biosynthetic processGO:00327743800.057
cellular catabolic processGO:00442482950.056
anterior posterior pattern specificationGO:000995210.055
regulation of protein metabolic processGO:00512462890.055
cardiovascular system developmentGO:00723581340.055
positive regulation of phosphorus metabolic processGO:00105622620.054
response to oxygen levelsGO:00704822650.053
response to lipopolysaccharideGO:00324961910.053
response to inorganic substanceGO:00100353770.053
cardiac conductionGO:006133720.052
protein complex subunit organizationGO:00718223020.051
negative regulation of metabolic processGO:00098923310.051
macromolecular complex assemblyGO:00650032730.051
cell type specific apoptotic processGO:00972851340.051
regulation of ion transportGO:00432692450.051
Human Mouse
neuron differentiationGO:00301823680.049
Mouse
positive regulation of molecular functionGO:00440932300.049
regulation of intracellular signal transductionGO:19025312180.049
purine containing compound metabolic processGO:00725212530.047
cellular response to organonitrogen compoundGO:00714171970.046
positive regulation of cellular biosynthetic processGO:00313282950.046
positive regulation of phosphate metabolic processGO:00459372620.045
response to estrogenGO:00436272320.045
reproductionGO:00000032450.044
peptidyl amino acid modificationGO:00181931260.044
reproductive processGO:00224143720.044
response to bacteriumGO:00096172000.044
cell communication involved in cardiac conductionGO:008606520.044
cell morphogenesis involved in neuron differentiationGO:00486671060.042
positive regulation of transportGO:00510502450.042
nucleobase containing small molecule metabolic processGO:00550863160.041
neuron projection morphogenesisGO:00488121220.041
response to biotic stimulusGO:00096072260.041
response to cytokineGO:00340972150.040
positive regulation of cell communicationGO:00106472710.040
single organism reproductive processGO:00447022970.039
positive regulation of rna metabolic processGO:00512542030.039
regulation of hormone levelsGO:00108171870.039
Mouse
regulation of rna metabolic processGO:00512523910.038
cellular response to endogenous stimulusGO:00714953770.038
cellular response to hormone stimulusGO:00328702470.037
programmed cell deathGO:00125013920.037
Human
nitrogen compound transportGO:00717052290.037
regulation of cellular protein metabolic processGO:00322682670.037
circulatory system developmentGO:00723591340.037
organophosphate metabolic processGO:00196373700.037
negative regulation of cellular metabolic processGO:00313242810.036
purine ribonucleotide metabolic processGO:00091502270.036
lipid metabolic processGO:00066292830.036
Mouse
negative regulation of gene expressionGO:00106291990.036
vesicle mediated transportGO:00161921810.035
response to other organismGO:00517072200.035
positive regulation of macromolecule biosynthetic processGO:00105572470.035
cellular component assemblyGO:00226073600.034
positive regulation of nitrogen compound metabolic processGO:00511733340.034
regulation of cellular amino acid metabolic processGO:000652120.034
cell cycle processGO:0022402570.034
muscle contractionGO:0006936880.033
Human Mouse
response to nutrient levelsGO:00316673700.033
synaptic transmissionGO:00072682350.033
Mouse
cellular amino acid metabolic processGO:00065201070.032
nucleic acid templated transcriptionGO:00976593790.032
nucleotide catabolic processGO:00091661390.031
protein heterooligomerizationGO:0051291890.031
secretion by cellGO:00329402480.031
establishment of protein localizationGO:00451841410.031
organic substance catabolic processGO:19015753160.031
regulation of nucleic acid templated transcriptionGO:19035063800.031
response to glucoseGO:00097491360.031
regulation of cellular localizationGO:00603412630.030
negative regulation of macromolecule metabolic processGO:00106052600.030
regenerationGO:00310991630.030
response to oxidative stressGO:00069791860.030
organic acid metabolic processGO:00060822920.030
positive regulation of developmental processGO:00510942830.030
protein homooligomerizationGO:0051260910.029
cell cycleGO:00070491010.029
organ morphogenesisGO:0009887750.029
response to anoxiaGO:003405940.029
regulation of anatomical structure morphogenesisGO:00226031410.028
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.028
single organism catabolic processGO:00447122830.028
positive regulation of protein metabolic processGO:00512471780.028
regulation of protein transportGO:0051223680.028
secretionGO:00469033070.028
Mouse
cation transportGO:00068123820.027
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.027
response to molecule of bacterial originGO:00022371940.027
developmental process involved in reproductionGO:00030061590.027
protein oligomerizationGO:00512591910.027
rna metabolic processGO:00160704060.027
chemical homeostasisGO:00488782920.027
Human
heart morphogenesisGO:000300730.026
positive regulation of cell proliferationGO:00082842490.026
detection of visible lightGO:000958430.026
neuromuscular synaptic transmissionGO:000727420.026
protein transportGO:00150311320.026
nucleotide metabolic processGO:00091172790.026
response to decreased oxygen levelsGO:00362932370.026
chemotaxisGO:0006935660.026
cell projection morphogenesisGO:00488581230.025
axonogenesisGO:0007409710.025
regulation of multicellular organismal developmentGO:20000263760.025
regulation of cell differentiationGO:00455953200.025
glycosyl compound catabolic processGO:19016581260.025
single organism organelle organizationGO:19025891800.025
regulation of phosphorylationGO:00423252480.025
glycosyl compound metabolic processGO:19016571820.025
positive regulation of cell deathGO:00109421840.025
Human
positive regulation of signalingGO:00230562700.025
positive regulation of apoptotic processGO:00430651540.024
Human
positive regulation of cellular component organizationGO:00511302000.024
macromolecule localizationGO:00330362520.024
purine nucleotide metabolic processGO:00061632290.024
ribonucleotide catabolic processGO:00092611360.024
regulation of apoptotic processGO:00429813350.024
Human
jnk cascadeGO:0007254280.024
regulation of cellular ketone metabolic processGO:0010565270.024
Mouse
multicellular organismal homeostasisGO:0048871490.024
positive regulation of nucleic acid templated transcriptionGO:19035081970.023
cellular macromolecule localizationGO:00707271220.023
hormone metabolic processGO:0042445690.023
Mouse
protein localizationGO:00081041910.023
calcium ion transmembrane transportGO:0070588700.023
regulation of cell developmentGO:00602842630.023
response to insulinGO:00328681330.023
nucleoside metabolic processGO:00091161790.023
ribonucleoside metabolic processGO:00091191740.023
organelle organizationGO:00069962660.023
development of primary female sexual characteristicsGO:0046545560.022
endoplasmic reticulum to cytosol transportGO:190351340.022
microtubule polymerization or depolymerizationGO:0031109130.022
positive regulation of nervous system developmentGO:00519621780.022
purine containing compound catabolic processGO:00725231380.022
cellular response to nitrogen compoundGO:19016992100.022
purine ribonucleoside metabolic processGO:00461281680.022
transcription dna templatedGO:00063513770.022
coronary vasculature morphogenesisGO:006097730.022
positive regulation of cell differentiationGO:00455972170.021
enzyme linked receptor protein signaling pathwayGO:00071671160.021
organonitrogen compound biosynthetic processGO:19015661670.021
cell morphogenesis involved in differentiationGO:00009041190.021
gonad developmentGO:00084061040.021
inorganic cation transmembrane transportGO:00986622020.021
cellular homeostasisGO:00197252520.021
Human Mouse
negative regulation of biosynthetic processGO:00098901680.021
neuron projection developmentGO:00311752730.021
response to extracellular stimulusGO:00099913800.021
cell growthGO:00160491040.021
positive regulation of phosphorylationGO:00423271770.021
ribose phosphate metabolic processGO:00196932350.020
cellular response to oxidative stressGO:0034599760.020
cellular response to growth factor stimulusGO:00713631620.020
signal transduction by phosphorylationGO:00230141440.020
nucleobase containing compound catabolic processGO:00346551520.020
protein tetramerizationGO:0051262380.020
regulation of protein phosphorylationGO:00019321830.020
calcium ion homeostasisGO:00550741620.020
positive regulation of cellular protein metabolic processGO:00322701670.020
cell part morphogenesisGO:00329901230.020
negative regulation of nucleic acid templated transcriptionGO:19035071170.020
protein autophosphorylationGO:0046777660.020
muscle cell proliferationGO:0033002840.020
nucleoside phosphate catabolic processGO:19012921400.020
sarcoplasmic reticulum calcium ion transportGO:007029680.019
cellular response to insulin stimulusGO:0032869810.019
regulation of cellular component biogenesisGO:0044087860.019
locomotionGO:00400112370.019
cell morphogenesisGO:00009021420.019
negative regulation of nitrogen compound metabolic processGO:00511721610.019
cellular component movementGO:00069282480.019
cellular protein complex assemblyGO:0043623440.019
cell cell signaling involved in cell fate commitmentGO:004516820.019
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.019
purine nucleotide catabolic processGO:00061951360.019
tube developmentGO:0035295890.019
axon guidanceGO:0007411240.019
tissue developmentGO:00098882520.019
Mouse
regulation of programmed cell deathGO:00430673410.019
Human
multicellular organismal reproductive processGO:00486092330.018
metal ion homeostasisGO:00550651860.018
Human
protein processingGO:0016485680.018
ion transmembrane transportGO:00342203650.018
positive regulation of catalytic activityGO:00430851840.018
response to woundingGO:00096112540.018
organophosphate catabolic processGO:00464341480.018
peptide secretionGO:0002790860.018
cellular amine metabolic processGO:0044106380.018
regulation of fat cell proliferationGO:007034410.018
neuronal action potentialGO:0019228350.018
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092051400.018
circulatory system processGO:00030131830.018
ribonucleoside catabolic processGO:00424541260.018
ion homeostasisGO:00508012120.017
Human
response to hypoxiaGO:00016662310.017
epithelial cell proliferationGO:0050673540.017
response to nutrientGO:00075842480.017
intracellular protein transportGO:0006886790.017
regulation of catabolic processGO:00098941130.017
cellular macromolecular complex assemblyGO:0034622580.017
cellular response to peptide hormone stimulusGO:00713751200.017
cellular nitrogen compound catabolic processGO:00442701630.017
positive regulation of transcription dna templatedGO:00458931970.017
nucleoside triphosphate catabolic processGO:00091431230.017
cell projection organizationGO:00300303020.017
epithelium developmentGO:0060429960.017
Mouse
multicellular organism growthGO:003526410.017
heterocycle catabolic processGO:00467001670.017
negative regulation of cellular protein metabolic processGO:00322691060.017
reproductive structure developmentGO:00486081280.017
cellular response to peptideGO:19016531330.017
positive regulation of cell developmentGO:00107201760.016
sex differentiationGO:00075481130.016
regulation of cellular component organizationGO:00511283680.016
development of primary sexual characteristicsGO:00451371070.016
regulation of cell morphogenesisGO:0022604770.016
negative regulation of response to stimulusGO:00485851550.016
cellular response to reactive oxygen speciesGO:0034614550.016
regulation of cellular catabolic processGO:00313291010.016
purine ribonucleoside triphosphate catabolic processGO:00092071220.016
adult locomotory behaviorGO:000834440.016
Mouse
female gonad developmentGO:0008585530.016
regulation of protein kinase activityGO:00458591050.016
transmembrane transportGO:00550854120.016
positive regulation of intracellular signal transductionGO:19025331380.016
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.016
smooth muscle cell proliferationGO:0048659770.016
carbohydrate derivative catabolic processGO:19011361470.015
nucleoside catabolic processGO:00091641260.015
localization of cellGO:00516742020.015
regulation of protein serine threonine kinase activityGO:0071900640.015
cellular cation homeostasisGO:00300031800.015
Human
purine ribonucleoside catabolic processGO:00461301240.015
positive regulation of cell motilityGO:2000147970.015
single organism biosynthetic processGO:00447113420.015
response to ketoneGO:19016541820.015
regulation of microtubule cytoskeleton organizationGO:0070507140.015
cellular response to oxygen containing compoundGO:19017013860.015
muscle tissue developmentGO:0060537580.015
sequestering of calcium ionGO:005120880.015
positive regulation of brown fat cell proliferationGO:007034910.015
organic cyclic compound catabolic processGO:19013611750.015
heart developmentGO:0007507720.015
positive regulation of cellular amine metabolic processGO:003324030.015
cytokinetic processGO:003250610.015
cellular component morphogenesisGO:00329891550.015
nucleoside phosphate metabolic processGO:00067532830.015
transcription from rna polymerase ii promoterGO:00063662520.015
agingGO:00075682410.014
regulation of hydrolase activityGO:00513361430.014
regulation of smooth muscle cell proliferationGO:0048660750.014
negative regulation of molecular functionGO:00440921330.014
cation homeostasisGO:00550801950.014
Human
neurological system processGO:00508772190.014
Mouse
cell motilityGO:00488702020.014
ribonucleoside triphosphate metabolic processGO:00091991410.014
positive regulation of kinase activityGO:0033674770.014
positive regulation of fat cell proliferationGO:007034610.014
amine metabolic processGO:0009308380.014
growthGO:00400071650.014
monocarboxylic acid metabolic processGO:00327871520.014
regulation of cell proliferationGO:00421273590.014
cellular lipid metabolic processGO:00442552080.014
positive regulation of rna biosynthetic processGO:19026801970.014
developmental growthGO:00485891000.014
sensory perceptionGO:00076001010.014
Mouse
regulation of homeostatic processGO:00328441010.014
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.014
regulation of rna biosynthetic processGO:20011413810.014
response to toxic substanceGO:00096361330.014
cellular metal ion homeostasisGO:00068751720.013
Human
respiratory system developmentGO:0060541450.013
regulation of secretionGO:00510462240.013
regulation of developmental growthGO:0048638450.013
ribonucleoside triphosphate catabolic processGO:00092031220.013
regulation of organ formationGO:000315620.013
neural crest cell developmentGO:001403220.013
purine ribonucleotide catabolic processGO:00091541360.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
g protein coupled receptor signaling pathwayGO:00071862420.013
negative regulation of rna biosynthetic processGO:19026791180.013
striated muscle contractionGO:0006941440.013
ovulation cycleGO:0042698670.013
response to light stimulusGO:0009416520.013
multi organism reproductive processGO:00447032620.013
morphogenesis of embryonic epitheliumGO:001633130.013
cellular ketone metabolic processGO:0042180510.013
Mouse
positive regulation of protein serine threonine kinase activityGO:0071902520.013
regulation of reactive oxygen species metabolic processGO:2000377260.013
small gtpase mediated signal transductionGO:0007264360.013
fat cell proliferationGO:007034120.013
regulation of peptidase activityGO:0052547550.012
mapk cascadeGO:00001651400.012
regulation of purine nucleotide metabolic processGO:19005421150.012
neuron projection guidanceGO:0097485240.012
dendrite developmentGO:0016358720.012
purine nucleoside triphosphate catabolic processGO:00091461220.012
salivary gland developmentGO:000743130.012
positive regulation of cardiac muscle cell proliferationGO:006004540.012
muscle structure developmentGO:0061061870.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
purine nucleoside metabolic processGO:00422781690.012
positive regulation of protein kinase activityGO:0045860730.012
positive regulation of programmed cell deathGO:00430681570.012
Human
regulation of peptide transportGO:0090087870.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
ras protein signal transductionGO:0007265290.012
guanosine containing compound metabolic processGO:1901068740.012
regulation of small gtpase mediated signal transductionGO:0051056480.012
cellular ion homeostasisGO:00068731840.012
Human
regulation of corticotropin secretionGO:005145970.012
brain developmentGO:00074202470.012
regulation of cellular amine metabolic processGO:003323880.012
male gamete generationGO:0048232990.012
sodium ion transmembrane transportGO:0035725670.012
organonitrogen compound catabolic processGO:19015651790.012
regulation of transcription dna templatedGO:00063553740.012
negative regulation of rna metabolic processGO:00512531230.012
response to peptideGO:19016522920.012
transmission of nerve impulseGO:0019226420.012
Mouse
gamete generationGO:00072761240.011
response to hydrogen peroxideGO:0042542890.011
regulation of axon extensionGO:0030516240.011
regulation of kinase activityGO:00435491170.011
reproductive system developmentGO:00614581280.011
gtp catabolic processGO:0006184710.011
positive regulation of protein phosphorylationGO:00019341350.011
cellular calcium ion homeostasisGO:00068741600.011
regulation of nucleotide catabolic processGO:0030811650.011
regulation of membrane potentialGO:00423911100.011
Human Mouse
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.011
mesoderm formationGO:000170710.011
protein maturationGO:0051604680.011
mesoderm developmentGO:000749820.011
oxidation reduction processGO:00551143040.011
regulation of cell migrationGO:00303341280.011
motor neuron axon guidanceGO:000804510.011
regulation of cell growthGO:0001558850.011
second messenger mediated signalingGO:0019932510.011
female sex differentiationGO:0046660590.011
negative regulation of cell communicationGO:00106481580.011
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.011
regulation of protein modification processGO:00313991940.011
eye morphogenesisGO:004859240.011
cardiac muscle contractionGO:0060048270.011
organ inductionGO:000175910.011
cardiac ventricle developmentGO:000323110.011
cytoplasmic transportGO:00164821150.010
carbohydrate derivative biosynthetic processGO:19011371240.010
regulation of proteolysisGO:0030162660.010
positive regulation of synaptic vesicle exocytosisGO:200030230.010
anatomical structure homeostasisGO:0060249290.010
single organism intracellular transportGO:19025821660.010
regulation of protein complex assemblyGO:0043254330.010
regulation of cellular component sizeGO:0032535510.010
lipid modificationGO:0030258520.010
negative regulation of transcription dna templatedGO:00458921160.010
sequestering of metal ionGO:005123890.010
gtp metabolic processGO:0046039720.010
negative regulation of microtubule depolymerizationGO:000702630.010
calcium ion importGO:0070509220.010
negative regulation of innate immune responseGO:004582440.010
intracellular transportGO:00469071850.010
single organism cellular localizationGO:19025801020.010

Kcnma1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye diseaseDOID:561400.047
nervous system diseaseDOID:86300.047
eye and adnexa diseaseDOID:149200.047
disease of anatomical entityDOID:700.047
sensory system diseaseDOID:005015500.047
retinal diseaseDOID:567900.028
retinal degenerationDOID:846600.016
substance related disorderDOID:30300.013
disease of mental healthDOID:15000.013
substance dependenceDOID:997300.013
disease of metabolismDOID:001466700.011
disease of cellular proliferationDOID:1456600.010
cancerDOID:16200.010