Rattus norvegicus

0 known processes

Arhgef12

Rho guanine nucleotide exchange factor (GEF) 12

(Aliases: Larg)

Arhgef12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of rna biosynthetic processGO:20011413810.120
regulation of rna metabolic processGO:00512523910.112
rna metabolic processGO:00160704060.102
positive regulation of nucleobase containing compound metabolic processGO:00459353190.091
positive regulation of nitrogen compound metabolic processGO:00511733340.085
negative regulation of macromolecule metabolic processGO:00106052600.085
transcription dna templatedGO:00063513770.084
negative regulation of metabolic processGO:00098923310.080
regulation of nucleic acid templated transcriptionGO:19035063800.080
neuron differentiationGO:00301823680.071
intracellular signal transductionGO:00355563140.067
negative regulation of cellular metabolic processGO:00313242810.067
cellular amino acid metabolic processGO:00065201070.066
positive regulation of cell communicationGO:00106472710.066
regulation of catalytic activityGO:00507903040.065
regulation of signal transductionGO:00099663180.061
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.059
carboxylic acid metabolic processGO:00197522890.058
central nervous system developmentGO:00074173110.058
cellular component movementGO:00069282480.055
regulation of phosphorus metabolic processGO:00511743490.054
protein phosphorylationGO:00064683450.054
organic acid metabolic processGO:00060822920.054
regulation of transcription dna templatedGO:00063553740.054
negative regulation of nucleic acid templated transcriptionGO:19035071170.054
negative regulation of cellular biosynthetic processGO:00313271610.053
anatomical structure morphogenesisGO:00096532980.053
negative regulation of biosynthetic processGO:00098901680.051
rna biosynthetic processGO:00327743800.050
regulation of intracellular signal transductionGO:19025312180.049
regulation of phosphate metabolic processGO:00192203490.049
positive regulation of cell differentiationGO:00455972170.049
single organism reproductive processGO:00447022970.049
regulation of molecular functionGO:00650093980.048
carbohydrate derivative metabolic processGO:19011353460.048
response to peptideGO:19016522920.047
positive regulation of nucleic acid templated transcriptionGO:19035081970.047
cellular response to endogenous stimulusGO:00714953770.047
programmed cell deathGO:00125013920.047
cellular response to oxygen containing compoundGO:19017013860.047
regulation of cell differentiationGO:00455953200.046
cellular response to hormone stimulusGO:00328702470.045
organelle organizationGO:00069962660.045
cellular component biogenesisGO:00440853680.045
single organism biosynthetic processGO:00447113420.045
positive regulation of rna biosynthetic processGO:19026801970.044
intracellular transportGO:00469071850.044
regulation of hydrolase activityGO:00513361430.044
positive regulation of biosynthetic processGO:00098913190.044
oxoacid metabolic processGO:00434362900.044
apoptotic processGO:00069153810.043
positive regulation of signalingGO:00230562700.043
transcription from rna polymerase ii promoterGO:00063662520.043
cellular response to stressGO:00335542690.043
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.043
positive regulation of cellular biosynthetic processGO:00313282950.042
head developmentGO:00603222470.042
positive regulation of transcription dna templatedGO:00458931970.041
positive regulation of multicellular organismal processGO:00512403870.041
regulation of cellular protein metabolic processGO:00322682670.041
response to decreased oxygen levelsGO:00362932370.041
agingGO:00075682410.040
positive regulation of developmental processGO:00510942830.040
positive regulation of phosphorus metabolic processGO:00105622620.038
response to nutrient levelsGO:00316673700.038
positive regulation of macromolecule biosynthetic processGO:00105572470.038
organophosphate metabolic processGO:00196373700.038
positive regulation of gene expressionGO:00106282440.038
regulation of protein metabolic processGO:00512462890.037
ribonucleotide metabolic processGO:00092592310.037
nucleoside metabolic processGO:00091161790.037
response to inorganic substanceGO:00100353770.037
positive regulation of signal transductionGO:00099671750.037
glycosyl compound metabolic processGO:19016571820.037
brain developmentGO:00074202470.037
positive regulation of rna metabolic processGO:00512542030.036
regulation of cell developmentGO:00602842630.036
regulation of cell proliferationGO:00421273590.036
nucleic acid templated transcriptionGO:00976593790.036
catabolic processGO:00090563510.036
response to insulinGO:00328681330.035
reproductive processGO:00224143720.035
regulation of transcription from rna polymerase ii promoterGO:00063572340.035
cell motilityGO:00488702020.035
regulation of neurogenesisGO:00507672470.035
ribose phosphate metabolic processGO:00196932350.035
developmental process involved in reproductionGO:00030061590.035
organic substance catabolic processGO:19015753160.034
negative regulation of gene expressionGO:00106291990.034
regulation of nervous system developmentGO:00519602640.034
cellular amine metabolic processGO:0044106380.034
positive regulation of cell proliferationGO:00082842490.033
nucleobase containing small molecule metabolic processGO:00550863160.033
cellular response to organonitrogen compoundGO:00714171970.033
macromolecular complex subunit organizationGO:00439333390.032
macromolecule localizationGO:00330362520.032
aromatic compound catabolic processGO:00194391680.032
regulation of cellular component organizationGO:00511283680.032
cellular response to nitrogen compoundGO:19016992100.032
cellular ketone metabolic processGO:0042180510.032
secretionGO:00469033070.032
purine ribonucleoside metabolic processGO:00461281680.032
regulation of cellular ketone metabolic processGO:0010565270.031
response to extracellular stimulusGO:00099913800.031
negative regulation of nitrogen compound metabolic processGO:00511721610.031
purine nucleotide metabolic processGO:00061632290.031
cell cell signalingGO:00072673350.031
protein complex subunit organizationGO:00718223020.031
cellular response to peptideGO:19016531330.031
protein complex assemblyGO:00064612630.031
single organism catabolic processGO:00447122830.031
positive regulation of nervous system developmentGO:00519621780.031
positive regulation of cellular amino acid metabolic processGO:004576410.031
amine metabolic processGO:0009308380.031
regulation of cellular amine metabolic processGO:003323880.031
purine containing compound metabolic processGO:00725212530.030
localization of cellGO:00516742020.030
response to peptide hormoneGO:00434342780.030
transmembrane transportGO:00550854120.030
regulation of cellular amino acid metabolic processGO:000652120.029
locomotionGO:00400112370.029
response to hypoxiaGO:00016662310.029
positive regulation of response to stimulusGO:00485842850.029
response to growth factorGO:00708481890.029
nucleotide metabolic processGO:00091172790.029
nucleoside phosphate metabolic processGO:00067532830.029
response to oxygen levelsGO:00704822650.029
positive regulation of phosphate metabolic processGO:00459372620.029
positive regulation of neurogenesisGO:00507691650.029
regulation of mesenchymal cell proliferationGO:001046440.028
purine ribonucleotide metabolic processGO:00091502270.028
development of primary sexual characteristicsGO:00451371070.028
response to nutrientGO:00075842480.028
single organism organelle organizationGO:19025891800.027
response to cytokineGO:00340972150.027
regulation of phosphorylationGO:00423252480.027
cell morphogenesis involved in differentiationGO:00009041190.027
regulation of programmed cell deathGO:00430673410.027
positive regulation of cell developmentGO:00107201760.027
ribonucleoside metabolic processGO:00091191740.027
single organism intracellular transportGO:19025821660.027
cellular response to organic cyclic compoundGO:00714072020.027
positive regulation of cellular amine metabolic processGO:003324030.026
tissue developmentGO:00098882520.026
cellular response to growth factor stimulusGO:00713631620.026
multicellular organismal reproductive processGO:00486092330.026
reproductive structure developmentGO:00486081280.026
regulation of cell motilityGO:20001451310.026
cell projection organizationGO:00300303020.026
homeostatic processGO:00425923310.026
negative regulation of nucleobase containing compound metabolic processGO:00459341530.026
nucleotide catabolic processGO:00091661390.025
cellular component morphogenesisGO:00329891550.025
cellular catabolic processGO:00442482950.025
ras protein signal transductionGO:0007265290.025
small gtpase mediated signal transductionGO:0007264360.025
enzyme linked receptor protein signaling pathwayGO:00071671160.025
regulation of anatomical structure morphogenesisGO:00226031410.024
establishment of protein localizationGO:00451841410.024
cellular component assemblyGO:00226073600.024
regulation of cellular component movementGO:00512701500.024
response to oxidative stressGO:00069791860.024
regulation of cellular localizationGO:00603412630.024
neuron developmentGO:00486662860.024
protein localizationGO:00081041910.024
sex differentiationGO:00075481130.024
mesenchymal cell proliferationGO:001046340.024
single organism membrane organizationGO:0044802740.023
regulation of purine nucleotide metabolic processGO:19005421150.023
negative regulation of macromolecule biosynthetic processGO:00105581480.023
negative regulation of multicellular organismal processGO:00512412030.023
regulation of multicellular organismal developmentGO:20000263760.023
negative regulation of cellular protein metabolic processGO:00322691060.023
multicellular organism reproductionGO:00325042330.023
purine nucleoside triphosphate catabolic processGO:00091461220.023
mapk cascadeGO:00001651400.023
purine nucleoside triphosphate metabolic processGO:00091441410.023
regulation of cellular catabolic processGO:00313291010.023
positive regulation of protein phosphorylationGO:00019341350.023
reproductionGO:00000032450.022
reproductive system developmentGO:00614581280.022
regulation of nucleotide metabolic processGO:00061401170.022
macromolecular complex assemblyGO:00650032730.022
positive regulation of purine nucleotide metabolic processGO:1900544910.022
multi organism reproductive processGO:00447032620.022
positive regulation of protein metabolic processGO:00512471780.022
regulation of apoptotic processGO:00429813350.022
positive regulation of molecular functionGO:00440932300.021
organic cyclic compound catabolic processGO:19013611750.021
neuron projection morphogenesisGO:00488121220.021
ribonucleoside triphosphate metabolic processGO:00091991410.021
positive regulation of hydrolase activityGO:0051345860.021
positive regulation of catalytic activityGO:00430851840.021
negative regulation of rna metabolic processGO:00512531230.021
regulation of secretion by cellGO:19035302080.021
regulation of neuron differentiationGO:00456642080.021
response to mechanical stimulusGO:00096121340.021
regulation of protein modification processGO:00313991940.021
cellular response to peptide hormone stimulusGO:00713751200.020
purine nucleoside metabolic processGO:00422781690.020
neuron projection developmentGO:00311752730.020
positive regulation of apoptotic processGO:00430651540.020
protein transportGO:00150311320.020
regulation of hormone levelsGO:00108171870.020
negative regulation of protein metabolic processGO:00512481140.020
regulation of mapk cascadeGO:00434081160.020
purine ribonucleotide catabolic processGO:00091541360.020
positive regulation of cellular component organizationGO:00511302000.019
regulation of cell projection organizationGO:00313441750.019
chemical homeostasisGO:00488782920.019
cell type specific apoptotic processGO:00972851340.019
cation transportGO:00068123820.019
negative regulation of programmed cell deathGO:00430691830.019
regulation of cellular component biogenesisGO:0044087860.019
regulation of transferase activityGO:00513381230.019
ribonucleoside triphosphate catabolic processGO:00092031220.019
carbohydrate metabolic processGO:00059751300.019
nucleoside catabolic processGO:00091641260.019
response to estrogenGO:00436272320.019
positive regulation of phosphorylationGO:00423271770.018
nucleoside phosphate catabolic processGO:19012921400.018
negative regulation of rna biosynthetic processGO:19026791180.018
response to toxic substanceGO:00096361330.018
response to glucocorticoidGO:00513842230.018
signal releaseGO:00230611450.018
establishment of tissue polarityGO:000716420.018
negative regulation of molecular functionGO:00440921330.018
regulation of catabolic processGO:00098941130.018
response to woundingGO:00096112540.018
taxisGO:0042330670.018
regulation of locomotionGO:00400121480.018
cellular homeostasisGO:00197252520.018
response to vitaminGO:00332731310.018
lipid localizationGO:0010876620.018
behaviorGO:00076102050.018
positive regulation of nucleotide metabolic processGO:0045981910.018
ion transmembrane transportGO:00342203650.018
cellular calcium ion homeostasisGO:00068741600.018
regulation of response to external stimulusGO:00321011060.018
cell morphogenesisGO:00009021420.018
heterocycle catabolic processGO:00467001670.018
nucleobase containing compound catabolic processGO:00346551520.018
proteolysisGO:00065081750.018
peptidyl tyrosine phosphorylationGO:0018108720.018
regulation of protein phosphorylationGO:00019321830.018
cellular nitrogen compound catabolic processGO:00442701630.018
response to bacteriumGO:00096172000.018
regulation of nucleoside metabolic processGO:0009118660.018
ribonucleoside catabolic processGO:00424541260.017
cellular chemical homeostasisGO:00550822470.017
negative regulation of cell communicationGO:00106481580.017
erythrocyte differentiationGO:003021810.017
cell migrationGO:00164771970.017
male sex differentiationGO:0046661640.017
regulation of system processGO:00440572080.017
cellular protein localizationGO:00346131220.017
cytoplasmic transportGO:00164821150.017
response to carbohydrateGO:00097431830.017
signal transduction by phosphorylationGO:00230141440.017
regulation of kinase activityGO:00435491170.017
positive regulation of neuron differentiationGO:00456661260.017
regulation of protein kinase activityGO:00458591050.017
ion homeostasisGO:00508012120.017
positive regulation of cell motilityGO:2000147970.017
carbohydrate derivative biosynthetic processGO:19011371240.017
positive regulation of mesenchymal cell proliferationGO:000205340.016
rhythmic processGO:00485111560.016
positive regulation of cell deathGO:00109421840.016
axis specificationGO:000979840.016
regulation of response to stressGO:00801341260.016
carbohydrate derivative catabolic processGO:19011361470.016
negative regulation of cellular component organizationGO:0051129830.016
g protein coupled receptor signaling pathwayGO:00071862420.016
regulation of stem cell differentiationGO:200073620.016
sexual reproductionGO:00199531480.016
response to ketoneGO:19016541820.016
response to estradiolGO:00323551640.016
multi multicellular organism processGO:00447061380.016
steroid metabolic processGO:0008202730.016
negative regulation of catalytic activityGO:00430861030.016
positive regulation of cell projection organizationGO:00313461110.016
cation homeostasisGO:00550801950.016
purine ribonucleoside catabolic processGO:00461301240.016
cellular response to cytokine stimulusGO:00713451270.016
secretion by cellGO:00329402480.016
b cell differentiationGO:003018320.016
purine ribonucleoside triphosphate catabolic processGO:00092071220.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.016
epithelium developmentGO:0060429960.016
ribonucleotide catabolic processGO:00092611360.015
organic anion transportGO:00157111320.015
negative regulation of cell deathGO:00605482290.015
positive regulation of cellular component movementGO:00512721020.015
negative regulation of apoptotic processGO:00430661810.015
negative regulation of transcription dna templatedGO:00458921160.015
muscle cell proliferationGO:0033002840.015
response to ammonium ionGO:0060359710.015
nucleoside triphosphate metabolic processGO:00091411440.015
response to molecule of bacterial originGO:00022371940.015
positive regulation of nucleoside metabolic processGO:0045979550.015
regulation of cell morphogenesisGO:0022604770.015
glycosyl compound catabolic processGO:19016581260.015
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.015
protein complex biogenesisGO:00702712630.015
intracellular protein transportGO:0006886790.015
positive regulation of cellular protein metabolic processGO:00322701670.015
positive regulation of transportGO:00510502450.015
embryonic pattern specificationGO:000988010.015
gonad developmentGO:00084061040.015
response to metal ionGO:00100382530.015
cellular response to lipidGO:00713962010.015
regulation of membrane potentialGO:00423911100.014
cellular metal ion homeostasisGO:00068751720.014
female pregnancyGO:00075651220.014
purine nucleoside catabolic processGO:00061521240.014
mesoderm developmentGO:000749820.014
defense responseGO:00069521940.014
cytokine biosynthetic processGO:004208930.014
positive regulation of intracellular signal transductionGO:19025331380.014
synaptic transmissionGO:00072682350.014
response to radiationGO:00093141370.014
response to alkaloidGO:00432791320.014
circulatory system processGO:00030131830.014
response to other organismGO:00517072200.014
regulation of neuron deathGO:19012141150.014
peptidyl amino acid modificationGO:00181931260.014
positive regulation of cell migrationGO:0030335960.014
anion transportGO:00068201780.014
negative regulation of developmental processGO:00510931250.014
response to amino acidGO:0043200750.014
smooth muscle cell proliferationGO:0048659770.014
positive regulation of protein modification processGO:00314011420.014
organophosphate catabolic processGO:00464341480.014
skeletal system developmentGO:0001501410.014
gliogenesisGO:0042063930.014
mechanoreceptor differentiationGO:004249020.014
eye morphogenesisGO:004859240.014
cytokine mediated signaling pathwayGO:0019221430.013
single organism carbohydrate metabolic processGO:00447231180.013
regulation of smooth muscle cell proliferationGO:0048660750.013
protein oligomerizationGO:00512591910.013
chemotaxisGO:0006935660.013
oxidation reduction processGO:00551143040.013
organonitrogen compound catabolic processGO:19015651790.013
regulation of cell migrationGO:00303341280.013
response to acid chemicalGO:00011012220.013
dephosphorylationGO:0016311980.013
response to corticosteroidGO:00319602350.013
organic acid transportGO:00158491160.013
regenerationGO:00310991630.013
multicellular organism growthGO:003526410.013
response to purine containing compoundGO:00140741260.013
regulation of nucleotide catabolic processGO:0030811650.013
organonitrogen compound biosynthetic processGO:19015661670.013
purine containing compound catabolic processGO:00725231380.013
regulation of reactive oxygen species biosynthetic processGO:190342650.013
purine nucleotide catabolic processGO:00061951360.013
negative regulation of phosphorus metabolic processGO:0010563800.013
axon developmentGO:0061564960.013
response to hydrogen peroxideGO:0042542890.013
anatomical structure formation involved in morphogenesisGO:0048646830.013
positive regulation of programmed cell deathGO:00430681570.013
activation of cysteine type endopeptidase activityGO:009720240.013
regulation of neuron projection developmentGO:00109751610.012
cellular response to alcoholGO:0097306870.012
reactive oxygen species biosynthetic processGO:190340980.012
peptidyl tyrosine modificationGO:0018212720.012
salivary gland developmentGO:000743130.012
protein processingGO:0016485680.012
negative regulation of signal transductionGO:0009968830.012
forebrain developmentGO:0030900980.012
regulation of secretionGO:00510462240.012
positive regulation of secretion by cellGO:19035321280.012
membrane organizationGO:0061024940.012
epithelial cell differentiation involved in kidney developmentGO:003585030.012
lipid storageGO:001991510.012
positive regulation of catabolic processGO:0009896780.012
ribonucleotide biosynthetic processGO:0009260850.012
inner ear receptor cell differentiationGO:006011320.012
tube developmentGO:0035295890.012
nucleoside triphosphate catabolic processGO:00091431230.012
positive regulation of locomotionGO:00400171020.012
regulation of protein localizationGO:0032880810.012
cytoskeleton organizationGO:00070101110.012
divalent inorganic cation homeostasisGO:00725071650.012
anion transmembrane transportGO:0098656770.012
cellular response to insulin stimulusGO:0032869810.012
nucleoside phosphate biosynthetic processGO:19012931020.012
response to ethanolGO:00454711620.012
epithelial cell differentiationGO:0030855710.012
rho protein signal transductionGO:0007266110.012
gtp catabolic processGO:0006184710.012
positive regulation of neuron projection developmentGO:0010976990.012
lipid metabolic processGO:00066292830.012
transmission of nerve impulseGO:0019226420.012
gamete generationGO:00072761240.011
metal ion homeostasisGO:00550651860.011
cellular cation homeostasisGO:00300031800.011
cellular response to oxidative stressGO:0034599760.011
protein autophosphorylationGO:0046777660.011
guanosine containing compound catabolic processGO:1901069710.011
regulation of cytokine productionGO:0001817560.011
defense response to gram negative bacteriumGO:005082930.011
anterior posterior pattern specificationGO:000995210.011
positive regulation of smooth muscle cell proliferationGO:0048661510.011
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
negative regulation of phosphate metabolic processGO:0045936800.011
erk1 and erk2 cascadeGO:0070371480.011
regulation of proteasomal protein catabolic processGO:006113640.011
cellular response to oxygen levelsGO:0071453600.011
calcium ion homeostasisGO:00550741620.011
negative regulation of response to stimulusGO:00485851550.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
divalent metal ion transportGO:00708381320.011
regulation of proteolysisGO:0030162660.011
response to lipopolysaccharideGO:00324961910.011
regulation of establishment of protein localizationGO:0070201690.011
negative regulation of cell proliferationGO:00082851190.011
divalent inorganic cation transportGO:00725111340.011
cell cycle checkpointGO:000007520.011
jak stat cascadeGO:0007259260.011
kidney developmentGO:0001822670.011
negative regulation of nervous system developmentGO:0051961790.011
male gonad developmentGO:0008584590.011
nitrogen compound transportGO:00717052290.011
negative regulation of kidney developmentGO:009018520.011
development of primary male sexual characteristicsGO:0046546590.011
cell differentiation involved in kidney developmentGO:006100540.011
alpha amino acid metabolic processGO:1901605710.011
negative regulation of signalingGO:00230571570.011
hair cell differentiationGO:003531520.011
cellular response to interleukin 1GO:0071347370.011
response to organophosphorusGO:00466831020.011
positive regulation of protein kinase activityGO:0045860730.011
cellular carbohydrate metabolic processGO:0044262720.011
protein maturationGO:0051604680.011
formation of primary germ layerGO:000170410.010
tissue remodelingGO:0048771400.010
response to activityGO:0014823730.010
telencephalon developmentGO:0021537620.010
action potentialGO:0001508540.010
epiboly involved in wound healingGO:009050520.010
chemosensory behaviorGO:000763520.010
cellular response to external stimulusGO:00714961180.010
regulation of blood circulationGO:19035221100.010
female gonad developmentGO:0008585530.010
cellular macromolecule localizationGO:00707271220.010
erythrocyte homeostasisGO:003410120.010
negative regulation of cell differentiationGO:0045596990.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
alcohol metabolic processGO:0006066770.010
positive regulation of mapk cascadeGO:0043410920.010
blood circulationGO:00080151830.010
regulation of immunoglobulin productionGO:000263740.010
single organism behaviorGO:00447081300.010
cellular divalent inorganic cation homeostasisGO:00725031620.010
axonogenesisGO:0007409710.010
cofactor metabolic processGO:0051186950.010
regulation of metanephros developmentGO:007221540.010
circulatory system developmentGO:00723591340.010
response to calcium ionGO:0051592590.010
regulation of body fluid levelsGO:0050878900.010

Arhgef12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.036
central nervous system diseaseDOID:33100.020
disease of metabolismDOID:001466700.011