Rattus norvegicus

0 known processes

Klk1b3

kallikrein 1-related peptidase b3

(Aliases: Ngfg,KLK1,preprokallikrein,Klk1c1,rGK-1)

Klk1b3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:00197522890.301
oxoacid metabolic processGO:00434362900.225
response to extracellular stimulusGO:00099913800.221
Rat
response to nutrient levelsGO:00316673700.184
Rat
response to inorganic substanceGO:00100353770.104
organic acid metabolic processGO:00060822920.102
ion transmembrane transportGO:00342203650.099
metal ion transportGO:00300012890.094
homeostatic processGO:00425923310.094
response to acid chemicalGO:00011012220.092
heart morphogenesisGO:000300730.081
Mouse
cellular amino acid metabolic processGO:00065201070.081
cellular amine metabolic processGO:0044106380.079
regulation of neurogenesisGO:00507672470.074
Rat
organonitrogen compound biosynthetic processGO:19015661670.074
Mouse
lymphoid progenitor cell differentiationGO:000232020.073
regulation of nucleic acid templated transcriptionGO:19035063800.071
neuron projection developmentGO:00311752730.070
Rat
small molecule biosynthetic processGO:00442831240.068
negative regulation of cellular metabolic processGO:00313242810.065
peptide biosynthetic processGO:004304330.065
Mouse
response to nutrientGO:00075842480.063
Rat
regulation of rna metabolic processGO:00512523910.062
regulation of cell proliferationGO:00421273590.061
regulation of neuron differentiationGO:00456642080.061
Rat
tissue developmentGO:00098882520.060
Mouse
neuron developmentGO:00486662860.060
Rat
localization of cellGO:00516742020.056
regulation of ion transportGO:00432692450.055
anatomical structure morphogenesisGO:00096532980.055
Mouse
response to metal ionGO:00100382530.051
blood circulationGO:00080151830.051
Mouse Rat
mesoderm developmentGO:000749820.051
amine metabolic processGO:0009308380.051
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.050
potassium ion transportGO:0006813970.050
positive regulation of cell proliferationGO:00082842490.050
macromolecular complex assemblyGO:00650032730.049
regulation of cellular amino acid metabolic processGO:000652120.048
negative regulation of nitrogen compound metabolic processGO:00511721610.048
response to oxygen levelsGO:00704822650.048
locomotionGO:00400112370.047
cation transportGO:00068123820.047
neuron differentiationGO:00301823680.046
Rat
anion transportGO:00068201780.045
regulation of cellular localizationGO:00603412630.045
regulation of multicellular organismal developmentGO:20000263760.045
Rat
chemical homeostasisGO:00488782920.045
response to corticosteroidGO:00319602350.044
divalent metal ion transportGO:00708381320.044
immune system processGO:00023762040.043
regulation of membrane potentialGO:00423911100.042
negative regulation of macromolecule metabolic processGO:00106052600.042
single organism biosynthetic processGO:00447113420.042
nucleic acid templated transcriptionGO:00976593790.042
intracellular signal transductionGO:00355563140.041
Mouse
regulation of nervous system developmentGO:00519602640.041
Rat
response to vitaminGO:00332731310.041
cellular ketone metabolic processGO:0042180510.041
regulation of apoptotic processGO:00429813350.040
monocarboxylic acid metabolic processGO:00327871520.040
cardiac muscle contractionGO:0060048270.040
Mouse
actin filament based processGO:0030029860.039
regulation of anatomical structure sizeGO:00900661350.039
Mouse Rat
store operated calcium entryGO:000211520.039
regulation of cellular ketone metabolic processGO:0010565270.039
positive regulation of intracellular signal transductionGO:19025331380.039
sodium ion transportGO:0006814820.039
calcium ion transportGO:00068161310.039
rna biosynthetic processGO:00327743800.038
regulation of cell differentiationGO:00455953200.038
Rat
response to glucocorticoidGO:00513842230.038
negative regulation of gene expressionGO:00106291990.038
protein maturationGO:0051604680.037
Mouse
central nervous system developmentGO:00074173110.037
regulation of metal ion transportGO:00109591180.037
behaviorGO:00076102050.037
apoptotic processGO:00069153810.037
single organism cellular localizationGO:19025801020.037
reproductionGO:00000032450.036
transmembrane transportGO:00550854120.036
negative regulation of cellular biosynthetic processGO:00313271610.036
cellular response to external stimulusGO:00714961180.036
response to estrogenGO:00436272320.035
positive regulation of transmembrane transportGO:0034764250.035
regulation of cellular component organizationGO:00511283680.035
Rat
secretion by cellGO:00329402480.034
response to cytokineGO:00340972150.034
organic anion transportGO:00157111320.034
cellular cation homeostasisGO:00300031800.034
monovalent inorganic cation transportGO:00156721720.034
cation transmembrane transportGO:00986552630.033
single organism reproductive processGO:00447022970.033
macromolecular complex subunit organizationGO:00439333390.032
catabolic processGO:00090563510.032
response to oxidative stressGO:00069791860.032
regulation of transcription dna templatedGO:00063553740.032
positive regulation of cellular component organizationGO:00511302000.031
cellular amide metabolic processGO:0043603440.031
Mouse
sexual reproductionGO:00199531480.031
cytosolic calcium ion homeostasisGO:00514801400.031
reproductive processGO:00224143720.030
regulation of cellular amine metabolic processGO:003323880.030
cell motilityGO:00488702020.030
multicellular organismal reproductive processGO:00486092330.030
regulation of rna biosynthetic processGO:20011413810.030
neural crest cell developmentGO:001403220.030
secretionGO:00469033070.029
proteolysisGO:00065081750.029
Mouse Rat
response to woundingGO:00096112540.029
peptidyl amino acid modificationGO:00181931260.029
response to hypoxiaGO:00016662310.028
cellular homeostasisGO:00197252520.028
regulation of protein metabolic processGO:00512462890.028
regulation of cell projection organizationGO:00313441750.028
Rat
kidney developmentGO:0001822670.028
positive regulation of multicellular organismal processGO:00512403870.027
Rat
response to growth factorGO:00708481890.027
single organism carbohydrate metabolic processGO:00447231180.027
protein complex biogenesisGO:00702712630.027
endocytosisGO:0006897840.027
response to estradiolGO:00323551640.027
organelle organizationGO:00069962660.027
protein phosphorylationGO:00064683450.027
regulation of catalytic activityGO:00507903040.027
Mouse
response to decreased oxygen levelsGO:00362932370.027
cellular response to oxygen containing compoundGO:19017013860.026
cellular response to abiotic stimulusGO:0071214850.026
neurological system processGO:00508772190.026
Mouse
response to ketoneGO:19016541820.026
amide biosynthetic processGO:0043604100.026
Mouse
positive regulation of cellular biosynthetic processGO:00313282950.026
defense responseGO:00069521940.026
Mouse
macromolecule localizationGO:00330362520.026
positive regulation of cytosolic calcium ion concentrationGO:00072041220.026
brain developmentGO:00074202470.025
head developmentGO:00603222470.025
cell projection organizationGO:00300303020.025
Rat
response to retinoic acidGO:0032526630.025
neural crest cell differentiationGO:001403320.025
regulation of phosphorus metabolic processGO:00511743490.024
Mouse
negative regulation of biosynthetic processGO:00098901680.024
cellular component movementGO:00069282480.024
regulation of blood vessel sizeGO:0050880890.023
Mouse Rat
cellular response to stressGO:00335542690.023
response to fungicideGO:0060992200.023
rna metabolic processGO:00160704060.023
response to amino acidGO:0043200750.023
cellular component biogenesisGO:00440853680.023
organic acid biosynthetic processGO:0016053830.023
inorganic cation transmembrane transportGO:00986622020.023
camera type eye developmentGO:0043010480.023
divalent inorganic cation transportGO:00725111340.022
regulation of protein modification processGO:00313991940.022
reproductive structure developmentGO:00486081280.022
regulation of response to stressGO:00801341260.022
positive regulation of gene expressionGO:00106282440.022
regulation of cell developmentGO:00602842630.022
Rat
positive regulation of rna metabolic processGO:00512542030.022
regulation of plasma lipoprotein particle levelsGO:009700630.022
lipid metabolic processGO:00066292830.021
Mouse
cell cell signalingGO:00072673350.021
regulation of pancreatic stellate cell proliferationGO:200022920.021
male sex differentiationGO:0046661640.021
lipid biosynthetic processGO:00086101280.021
negative regulation of multicellular organismal processGO:00512412030.021
stress activated protein kinase signaling cascadeGO:0031098370.021
inorganic ion transmembrane transportGO:00986602290.021
sensory organ developmentGO:0007423740.021
response to biotic stimulusGO:00096072260.021
multicellular organism reproductionGO:00325042330.021
sodium ion transmembrane transportGO:0035725670.021
regulation of ion transmembrane transportGO:00347651210.021
multi organism reproductive processGO:00447032620.021
negative regulation of macromolecule biosynthetic processGO:00105581480.021
circulatory system processGO:00030131830.021
Mouse Rat
cellular lipid metabolic processGO:00442552080.021
Mouse
sulfur compound biosynthetic processGO:0044272190.020
cellular component assemblyGO:00226073600.020
cellular response to cytokine stimulusGO:00713451270.020
response to toxic substanceGO:00096361330.020
positive regulation of signalingGO:00230562700.020
cardiac chamber developmentGO:000320510.020
Mouse
cell migrationGO:00164771970.020
metal ion homeostasisGO:00550651860.020
protein complex subunit organizationGO:00718223020.020
protein complex assemblyGO:00064612630.020
vasoconstrictionGO:0042310540.020
Rat
regulation of transcription from rna polymerase ii promoterGO:00063572340.020
divalent inorganic cation homeostasisGO:00725071650.020
carboxylic acid biosynthetic processGO:0046394830.020
jnk cascadeGO:0007254280.020
tube formationGO:003514830.020
fatty acid metabolic processGO:0006631990.019
regulation of programmed cell deathGO:00430673410.019
fertilizationGO:000956630.019
oxidation reduction processGO:00551143040.019
erythrocyte differentiationGO:003021810.019
vesicle mediated transportGO:00161921810.019
lens fiber cell differentiationGO:007030630.019
urogenital system developmentGO:0001655780.019
positive regulation of cell differentiationGO:00455972170.019
negative regulation of transcription dna templatedGO:00458921160.019
development of primary sexual characteristicsGO:00451371070.019
muscle system processGO:00030121150.019
Mouse
organic hydroxy compound metabolic processGO:19016151150.019
positive regulation of developmental processGO:00510942830.019
cellular divalent inorganic cation homeostasisGO:00725031620.019
developmental process involved in reproductionGO:00030061590.019
embryonic neurocranium morphogenesisGO:004870220.019
regulation of phosphate metabolic processGO:00192203490.018
Mouse
cellular chemical homeostasisGO:00550822470.018
regulation of vasoconstrictionGO:0019229440.018
Rat
positive regulation of secretionGO:00510471400.018
regulation of intracellular signal transductionGO:19025312180.018
adult locomotory behaviorGO:000834440.018
negative regulation of rna biosynthetic processGO:19026791180.018
response to alkaloidGO:00432791320.018
Rat
positive regulation of cellular amino acid metabolic processGO:004576410.018
response to monosaccharideGO:00342841590.018
response to molecule of bacterial originGO:00022371940.018
multicellular organism growthGO:003526410.018
ion homeostasisGO:00508012120.018
regulation of phosphorylationGO:00423252480.018
Mouse
positive regulation of cellular amine metabolic processGO:003324030.018
adenylate cyclase inhibiting serotonin receptor signaling pathwayGO:000719810.018
lipid transportGO:0006869610.017
regulation of fat cell differentiationGO:004559830.017
muscle structure developmentGO:0061061870.017
Mouse
forebrain developmentGO:0030900980.017
eye morphogenesisGO:004859240.017
organic acid transportGO:00158491160.017
programmed cell deathGO:00125013920.017
hormone metabolic processGO:0042445690.017
carboxylic acid transportGO:00469421150.017
organophosphate biosynthetic processGO:00904071430.017
negative regulation of transportGO:00510511360.017
cerebral cortex tangential migrationGO:002180010.017
positive regulation of molecular functionGO:00440932300.017
Mouse
cellular metal ion homeostasisGO:00068751720.017
regulation of calcium ion transportGO:0051924770.017
cation homeostasisGO:00550801950.017
cellular ion homeostasisGO:00068731840.017
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044130.017
Mouse
positive regulation of programmed cell deathGO:00430681570.016
response to carbohydrateGO:00097431830.016
intracellular transportGO:00469071850.016
single organism catabolic processGO:00447122830.016
pancreatic stellate cell proliferationGO:007234320.016
negative regulation of cell deathGO:00605482290.016
ovulation cycle processGO:0022602500.016
negative regulation of metabolic processGO:00098923310.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
response to hexoseGO:00097461440.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
transcription dna templatedGO:00063513770.016
cellular response to organic cyclic compoundGO:00714072020.016
regulation of ion transmembrane transporter activityGO:0032412480.016
small gtpase mediated signal transductionGO:0007264360.016
Mouse
positive regulation of biosynthetic processGO:00098913190.016
regulation of stem cell differentiationGO:200073620.015
response to nicotineGO:0035094510.015
Rat
cell morphogenesis involved in differentiationGO:00009041190.015
regulation of homeostatic processGO:00328441010.015
positive regulation of phosphate metabolic processGO:00459372620.015
Mouse
calcium ion homeostasisGO:00550741620.015
positive regulation of extracellular matrix organizationGO:190305540.015
regulation of transporter activityGO:0032409500.015
response to acetateGO:001003430.015
positive regulation of ion transmembrane transportGO:0034767240.015
mapk cascadeGO:00001651400.015
regulation of cell migrationGO:00303341280.015
single organism intracellular transportGO:19025821660.015
regulation of neuron projection developmentGO:00109751610.015
Rat
positive regulation of long term synaptic potentiationGO:190027340.015
positive regulation of lipid kinase activityGO:009021820.015
Mouse
cell adhesionGO:00071551100.015
alpha amino acid metabolic processGO:1901605710.015
parasympathetic nervous system developmentGO:004848610.015
cellular carbohydrate metabolic processGO:0044262720.014
positive regulation of ion transportGO:0043270940.014
regulation of cellular protein metabolic processGO:00322682670.014
multicellular organismal signalingGO:0035637440.014
regulation of membrane repolarizationGO:006030610.014
action potentialGO:0001508540.014
wound healingGO:00420601220.014
neuronal action potentialGO:0019228350.014
gonad developmentGO:00084061040.014
cardiovascular system developmentGO:00723581340.014
Mouse
response to testosteroneGO:0033574550.014
glucose metabolic processGO:0006006520.014
brain renin angiotensin systemGO:000203530.014
Mouse
negative regulation of serine type endopeptidase activityGO:190000410.014
kidney epithelium developmentGO:0072073190.014
positive regulation of phosphorylationGO:00423271770.014
Mouse
protein localizationGO:00081041910.014
skeletal system developmentGO:0001501410.014
regulation of immune system processGO:00026821230.014
positive regulation of cellular protein metabolic processGO:00322701670.014
regulation of protein phosphorylationGO:00019321830.014
regulation of mapk cascadeGO:00434081160.014
positive regulation of cell deathGO:00109421840.014
cytoskeleton organizationGO:00070101110.014
regulation of body fluid levelsGO:0050878900.014
male gamete generationGO:0048232990.013
inner ear receptor cell differentiationGO:006011320.013
positive regulation of nitrogen compound metabolic processGO:00511733340.013
cellular response to endogenous stimulusGO:00714953770.013
positive regulation of catalytic activityGO:00430851840.013
Mouse
macromolecule catabolic processGO:0009057580.013
regulation of kinase activityGO:00435491170.013
Mouse
cellular response to growth factor stimulusGO:00713631620.013
regulation of anatomical structure morphogenesisGO:00226031410.013
cellular response to acid chemicalGO:0071229750.013
carbohydrate derivative metabolic processGO:19011353460.013
response to glucoseGO:00097491360.013
single organism organelle organizationGO:19025891800.013
negative regulation of apoptotic processGO:00430661810.013
pro t cell differentiationGO:000257210.013
regulation of molecular functionGO:00650093980.013
Mouse
regulation of system processGO:00440572080.013
Rat
positive regulation of hepatocyte differentiationGO:007036820.013
cardiac muscle cell contractionGO:0086003100.013
organophosphate metabolic processGO:00196373700.013
Mouse
response to other organismGO:00517072200.013
alcohol metabolic processGO:0006066770.013
response to mineralocorticoidGO:0051385490.013
positive regulation of immune system processGO:0002684900.013
organic substance catabolic processGO:19015753160.013
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.013
negative regulation of programmed cell deathGO:00430691830.013
positive regulation of nucleobase containing compound metabolic processGO:00459353190.013
carbohydrate derivative catabolic processGO:19011361470.013
positive regulation of cell developmentGO:00107201760.013
protein processingGO:0016485680.013
Mouse
mesenchymal to epithelial transitionGO:006023130.013
renin secretion into blood streamGO:000200110.012
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.012
cellular response to nitrogen compoundGO:19016992100.012
plasma lipoprotein particle clearanceGO:003438130.012
regulation of brown fat cell proliferationGO:007034710.012
cell projection morphogenesisGO:00488581230.012
heart developmentGO:0007507720.012
Mouse
chromosome segregationGO:000705920.012
monocarboxylic acid biosynthetic processGO:0072330480.012
cell communication involved in cardiac conductionGO:008606520.012
signal transduction by phosphorylationGO:00230141440.012
reproductive system developmentGO:00614581280.012
nucleobase containing small molecule metabolic processGO:00550863160.012
growthGO:00400071650.012
positive regulation of cell communicationGO:00106472710.012
stress activated mapk cascadeGO:0051403350.012
cell morphogenesisGO:00009021420.012
gamete generationGO:00072761240.012
dephosphorylationGO:0016311980.012
epithelial cell differentiation involved in kidney developmentGO:003585030.012
cellular calcium ion homeostasisGO:00068741600.012
cartilage developmentGO:0051216220.012
response to peptide hormoneGO:00434342780.012
regulation of signal transductionGO:00099663180.012
cellular catabolic processGO:00442482950.012
nitrogen compound transportGO:00717052290.012
ovulation cycleGO:0042698670.012
cellular nitrogen compound catabolic processGO:00442701630.011
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.011
Mouse
regulation of vesicle mediated transportGO:0060627810.011
positive regulation of apoptotic processGO:00430651540.011
organ morphogenesisGO:0009887750.011
Mouse
cytoplasmic transportGO:00164821150.011
mechanoreceptor differentiationGO:004249020.011
protein oligomerizationGO:00512591910.011
actin cytoskeleton organizationGO:0030036730.011
negative regulation of cellular amine metabolic processGO:003323930.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
hexose metabolic processGO:0019318580.011
substrate dependent cerebral cortex tangential migrationGO:002182510.011
regulation of endocytosisGO:0030100420.011
gastrulationGO:000736920.011
cardiac muscle tissue growthGO:0055017200.011
positive regulation of response to stimulusGO:00485842850.011
bone developmentGO:0060348250.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
transmission of nerve impulseGO:0019226420.011
cardiac muscle tissue morphogenesisGO:005500810.011
Mouse
bmp signaling pathwayGO:003050940.011
response to foodGO:0032094270.011
regulation of response to external stimulusGO:00321011060.011
muscle contractionGO:0006936880.011
Mouse
agingGO:00075682410.011
heart contractionGO:0060047570.011
Mouse
morphogenesis of embryonic epitheliumGO:001633130.011
response to bacteriumGO:00096172000.011
acrosome assemblyGO:000167530.011
negative regulation of signalingGO:00230571570.011
response to external biotic stimulusGO:00432072210.011
cellular protein localizationGO:00346131220.011
negative regulation of cell developmentGO:0010721820.011
cellular biogenic amine metabolic processGO:0006576300.011
hematopoietic progenitor cell differentiationGO:000224420.011
positive regulation of locomotionGO:00400171020.011
response to transition metal nanoparticleGO:19902671220.011
female sex differentiationGO:0046660590.011
positive regulation of cell motilityGO:2000147970.011
negative regulation of axon guidanceGO:190266830.011
saliva secretionGO:004654130.010
regulation of tube sizeGO:0035150890.010
Mouse Rat
positive regulation of neuron migrationGO:200122420.010
striated muscle tissue developmentGO:0014706580.010
Mouse
negative regulation of response to stimulusGO:00485851550.010
nucleoside triphosphate metabolic processGO:00091411440.010
cellular component morphogenesisGO:00329891550.010
negative regulation of rna metabolic processGO:00512531230.010
regenerationGO:00310991630.010
developmental inductionGO:003112820.010
rho protein signal transductionGO:0007266110.010
sex differentiationGO:00075481130.010
single organism membrane organizationGO:0044802740.010
response to peptideGO:19016522920.010
regulation of b cell differentiationGO:004557710.010
regulation of the force of heart contraction by chemical signalGO:000305720.010
positive regulation of neurogenesisGO:00507691650.010
circulatory system developmentGO:00723591340.010
Mouse
regulation of ion homeostasisGO:2000021630.010

Klk1b3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
urinary system diseaseDOID:1800.041
kidney diseaseDOID:55700.041
disease of anatomical entityDOID:700.041
nervous system diseaseDOID:86300.028
sensory system diseaseDOID:005015500.027
central nervous system diseaseDOID:33100.013
musculoskeletal system diseaseDOID:1700.010