Rattus norvegicus

0 known processes

RT1-EC2

RT1 class Ib, locus EC2

(Aliases: RT1-Aw2,RT1Aw2,RT1.Al,RATMHCRTA,MHCRTA,RTS,RT1.EC2,RT1-A)

RT1-EC2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
antigen processing and presentation of endogenous antigenGO:001988311.000
positive regulation of tolerance inductionGO:000264511.000
regulation of tolerance induction dependent upon immune responseGO:000265211.000
t cell tolerance inductionGO:000251731.000
cellular response to iron ion starvationGO:001010610.999
positive regulation of tolerance induction dependent upon immune responseGO:000265410.999
regulation of tolerance induction to nonself antigenGO:000265510.999
negative regulation of natural killer cell mediated immunityGO:000271640.999
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.998
positive regulation of leukocyte mediated cytotoxicityGO:000191270.997
positive regulation of tolerance induction to nonself antigenGO:000265710.996
positive regulation of t cell mediated cytotoxicityGO:000191640.990
tolerance induction dependent upon immune responseGO:000246120.989
regulation of natural killer cell mediated cytotoxicityGO:004226960.987
regulation of cell killingGO:0031341120.983
negative regulation of cell killingGO:003134250.980
antigen processing and presentation of endogenous peptide antigen via mhc class iGO:001988510.972
tolerance induction to nonself antigenGO:000246220.959
antigen processing and presentation of peptide antigen via mhc class iGO:000247410.951
regulation of tolerance inductionGO:000264320.947
natural killer cell mediated cytotoxicityGO:004226760.945
positive regulation of leukocyte mediated immunityGO:0002705130.839
antigen processing and presentationGO:001988220.821
cell killingGO:0001906130.817
natural killer cell mediated immunityGO:000222860.750
regulation of adaptive immune responseGO:000281980.739
negative regulation of leukocyte mediated immunityGO:000270460.680
positive regulation of cell killingGO:003134390.666
leukocyte mediated cytotoxicityGO:0001909100.640
negative regulation of innate immune responseGO:004582440.613
regulation of leukocyte mediated cytotoxicityGO:0001910100.610
positive regulation of adaptive immune responseGO:000282160.605
antigen processing and presentation of peptide antigenGO:004800220.584
t cell mediated cytotoxicityGO:000191350.559
regulation of leukocyte mediated immunityGO:0002703190.527
acute phase responseGO:0006953200.499
immune effector processGO:0002252530.430
organ regenerationGO:00311001010.404
ion homeostasisGO:00508012120.364
positive regulation of immune system processGO:0002684900.361
negative regulation of lymphocyte mediated immunityGO:000270750.358
response to virusGO:0009615170.346
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000282280.343
t cell mediated immunityGO:000245670.343
response to external biotic stimulusGO:00432072210.328
response to extracellular stimulusGO:00099913800.320
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000282460.318
cellular response to external stimulusGO:00714961180.318
gland developmentGO:00487321550.314
positive regulation of immune effector processGO:0002699190.306
defense responseGO:00069521940.303
regulation of innate immune responseGO:0045088150.298
response to starvationGO:0042594590.291
metal ion homeostasisGO:00550651860.285
cellular response to extracellular stimulusGO:0031668730.276
sensory organ developmentGO:0007423740.269
innate immune responseGO:0045087350.261
leukocyte mediated immunityGO:0002443280.257
positive regulation of lymphocyte mediated immunityGO:000270870.247
glycosyl compound catabolic processGO:19016581260.244
regulation of t cell mediated cytotoxicityGO:000191450.231
adaptive immune responseGO:0002250140.227
response to other organismGO:00517072200.207
homeostatic processGO:00425923310.197
negative regulation of defense responseGO:0031348190.195
immune responseGO:00069551040.192
regulation of natural killer cell mediated immunityGO:000271560.186
positive regulation of t cell mediated immunityGO:000271140.182
female pregnancyGO:00075651220.178
immune system developmentGO:0002520410.172
liver developmentGO:0001889900.167
regulation of immune system processGO:00026821230.161
cellular response to stressGO:00335542690.158
purine nucleoside monophosphate metabolic processGO:0009126840.153
regulation of defense responseGO:0031347680.151
immune system processGO:00023762040.142
cellular response to starvationGO:0009267270.138
acute inflammatory responseGO:0002526580.128
multi multicellular organism processGO:00447061380.127
antigen processing and presentation of exogenous peptide antigenGO:000247810.125
positive regulation of gene expressionGO:00106282440.124
organophosphate metabolic processGO:00196373700.124
negative regulation of immune effector processGO:0002698120.123
antigen processing and presentation of exogenous antigenGO:001988410.122
cation homeostasisGO:00550801950.121
purine ribonucleoside monophosphate metabolic processGO:0009167840.115
regulation of cellular ketone metabolic processGO:0010565270.113
protection from natural killer cell mediated cytotoxicityGO:004227020.113
hepaticobiliary system developmentGO:0061008900.112
response to hexoseGO:00097461440.109
regulation of response to stressGO:00801341260.109
cellular response to nutrient levelsGO:0031669600.109
response to cytokineGO:00340972150.108
negative regulation of response to stimulusGO:00485851550.107
tolerance inductionGO:000250750.107
ribonucleoside triphosphate metabolic processGO:00091991410.104
macromolecular complex assemblyGO:00650032730.103
positive regulation of rna metabolic processGO:00512542030.103
positive regulation of multicellular organismal processGO:00512403870.101
chemical homeostasisGO:00488782920.098
lymphocyte mediated immunityGO:0002449140.096
multi organism reproductive processGO:00447032620.096
response to nutrient levelsGO:00316673700.094
glycosyl compound metabolic processGO:19016571820.091
cellular component biogenesisGO:00440853680.090
purine nucleoside monophosphate catabolic processGO:0009128550.087
catabolic processGO:00090563510.087
positive regulation of humoral immune responseGO:000292220.087
protein complex biogenesisGO:00702712630.086
macromolecular complex subunit organizationGO:00439333390.086
nucleoside monophosphate metabolic processGO:0009123930.086
response to molecule of bacterial originGO:00022371940.083
reproductive processGO:00224143720.082
regulation of homotypic cell cell adhesionGO:003411040.080
response to bacteriumGO:00096172000.079
response to corticosteroidGO:00319602350.079
extracellular transportGO:000685810.079
regulation of multicellular organismal developmentGO:20000263760.078
cellular component assemblyGO:00226073600.077
regenerationGO:00310991630.076
purine ribonucleoside metabolic processGO:00461281680.076
regulation of antigen processing and presentationGO:000257710.076
nucleoside phosphate metabolic processGO:00067532830.076
positive regulation of immune responseGO:0050778420.072
cellular ketone metabolic processGO:0042180510.071
inflammatory responseGO:00069541500.070
positive regulation of response to stimulusGO:00485842850.066
regulation of t cell mediated immunityGO:000270960.064
regulation of lymphocyte mediated immunityGO:0002706110.062
nucleoside triphosphate catabolic processGO:00091431230.059
negative regulation of immune responseGO:0050777150.059
amide transportGO:00428861050.059
cellular amino acid metabolic processGO:00065201070.059
purine nucleoside triphosphate catabolic processGO:00091461220.057
jak stat cascadeGO:0007259260.056
protein complex subunit organizationGO:00718223020.056
regulation of immune effector processGO:0002697320.055
cellular response to peptide hormone stimulusGO:00713751200.053
regulation of cellular amino acid metabolic processGO:000652120.053
olfactory learningGO:000835510.052
organonitrogen compound catabolic processGO:19015651790.051
purine ribonucleoside triphosphate metabolic processGO:00092051400.051
positive regulation of cellular biosynthetic processGO:00313282950.050
nucleoside monophosphate catabolic processGO:0009125560.050
cellular amine metabolic processGO:0044106380.048
response to ketoneGO:19016541820.048
response to purine containing compoundGO:00140741260.048
purine ribonucleoside catabolic processGO:00461301240.047
ribonucleotide metabolic processGO:00092592310.047
atp catabolic processGO:0006200540.047
response to vitaminGO:00332731310.046
single organism intracellular transportGO:19025821660.046
positive regulation of nervous system developmentGO:00519621780.045
protein complex assemblyGO:00064612630.045
protein transportGO:00150311320.045
cellular response to organic cyclic compoundGO:00714072020.044
cellular catabolic processGO:00442482950.044
establishment of protein localizationGO:00451841410.043
nucleoside triphosphate metabolic processGO:00091411440.043
defense response to virusGO:005160790.042
ribonucleoside metabolic processGO:00091191740.042
regulation of neuron deathGO:19012141150.042
nucleoside metabolic processGO:00091161790.041
response to lipopolysaccharideGO:00324961910.041
myeloid leukocyte activationGO:0002274360.041
regulation of leukocyte migrationGO:0002685240.041
regulation of body fluid levelsGO:0050878900.041
organophosphate catabolic processGO:00464341480.041
response to organophosphorusGO:00466831020.040
cellular response to biotic stimulusGO:0071216590.040
purine nucleotide catabolic processGO:00061951360.040
regulation of cell developmentGO:00602842630.040
positive regulation of transcription dna templatedGO:00458931970.040
response to estrogenGO:00436272320.039
response to biotic stimulusGO:00096072260.039
ribose phosphate metabolic processGO:00196932350.039
cellular macromolecular complex assemblyGO:0034622580.039
purine ribonucleotide metabolic processGO:00091502270.038
response to estradiolGO:00323551640.038
nucleobase containing compound catabolic processGO:00346551520.037
amine metabolic processGO:0009308380.037
rna metabolic processGO:00160704060.037
positive regulation of cellular component movementGO:00512721020.036
response to radiationGO:00093141370.036
ribonucleoside monophosphate catabolic processGO:0009158550.036
spindle organizationGO:000705120.036
cellular response to interleukin 1GO:0071347370.036
positive regulation of programmed cell deathGO:00430681570.036
atp metabolic processGO:0046034720.035
positive regulation of cell deathGO:00109421840.035
response to monosaccharideGO:00342841590.035
single organism catabolic processGO:00447122830.035
response to hydrogen peroxideGO:0042542890.035
interleukin 1 secretionGO:005070130.035
purine nucleoside catabolic processGO:00061521240.034
response to reactive oxygen speciesGO:00003021200.034
leukocyte activationGO:0045321760.034
organic substance catabolic processGO:19015753160.034
b cell mediated immunityGO:001972440.034
response to glucocorticoidGO:00513842230.034
nucleoside catabolic processGO:00091641260.033
regulation of interferon gamma productionGO:003264930.033
ribonucleoside triphosphate catabolic processGO:00092031220.033
ribonucleotide catabolic processGO:00092611360.033
mitotic spindle organizationGO:000705220.033
intracellular protein transportGO:0006886790.033
neuron deathGO:00709971270.032
regulation of cell projection organizationGO:00313441750.032
cellular homeostasisGO:00197252520.032
positive regulation of nitrogen compound metabolic processGO:00511733340.031
carbohydrate derivative catabolic processGO:19011361470.031
myeloid leukocyte migrationGO:0097529200.031
peptidyl tyrosine autophosphorylationGO:003808310.031
nucleobase containing small molecule metabolic processGO:00550863160.031
positive regulation of nucleobase containing compound metabolic processGO:00459353190.031
response to hypoxiaGO:00016662310.031
response to molecule of fungal originGO:000223830.031
cellular response to nitrogen compoundGO:19016992100.031
positive regulation of cellular amine metabolic processGO:003324030.030
regulation of cellular amine metabolic processGO:003323880.030
purine nucleoside triphosphate metabolic processGO:00091441410.030
response to carbohydrateGO:00097431830.030
neuron projection developmentGO:00311752730.030
secretionGO:00469033070.030
purine containing compound catabolic processGO:00725231380.029
positive regulation of lymphocyte migrationGO:200040310.029
organic cyclic compound catabolic processGO:19013611750.029
response to peptide hormoneGO:00434342780.029
circulatory system processGO:00030131830.028
purine ribonucleoside monophosphate catabolic processGO:0009169550.028
response to decreased oxygen levelsGO:00362932370.028
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.028
cytokine mediated signaling pathwayGO:0019221430.028
regulation of cytokine productionGO:0001817560.028
cellular response to molecule of bacterial originGO:0071219560.028
cellular response to oxygen containing compoundGO:19017013860.028
peptide transportGO:0015833970.027
aromatic compound catabolic processGO:00194391680.027
peptide biosynthetic processGO:004304330.027
nucleoside phosphate catabolic processGO:19012921400.027
positive regulation of nucleoside metabolic processGO:0045979550.027
head developmentGO:00603222470.027
response to nutrientGO:00075842480.027
regulation of immune responseGO:0050776550.026
multicellular organism reproductionGO:00325042330.026
lymphocyte homeostasisGO:000226020.026
intracellular transportGO:00469071850.026
response to dexamethasoneGO:0071548490.025
glial cell apoptotic processGO:003434980.025
cell chemotaxisGO:0060326310.025
cytoplasmic transportGO:00164821150.024
brain developmentGO:00074202470.024
ribonucleoside monophosphate metabolic processGO:0009161880.024
positive regulation of cellular amino acid metabolic processGO:004576410.024
regulation of cellular catabolic processGO:00313291010.023
heterocycle catabolic processGO:00467001670.023
positive regulation of cell projection organizationGO:00313461110.023
protein modification by small protein conjugationGO:0032446310.023
oxoacid metabolic processGO:00434362900.023
ribonucleoside catabolic processGO:00424541260.023
iron ion homeostasisGO:005507230.022
purine ribonucleoside triphosphate catabolic processGO:00092071220.022
response to inorganic substanceGO:00100353770.022
cellular response to tumor necrosis factorGO:0071356460.022
nucleotide catabolic processGO:00091661390.022
regulation of smooth muscle cell proliferationGO:0048660750.022
response to oxygen levelsGO:00704822650.022
response to acid chemicalGO:00011012220.022
cellular macromolecule localizationGO:00707271220.022
neuron developmentGO:00486662860.022
regulation of jak stat cascadeGO:0046425210.022
response to tumor necrosis factorGO:0034612560.022
neurological system processGO:00508772190.021
purine nucleoside metabolic processGO:00422781690.021
apoptotic processGO:00069153810.021
sodium ion transportGO:0006814820.021
protein localizationGO:00081041910.021
cellular response to hormone stimulusGO:00328702470.021
cell part morphogenesisGO:00329901230.021
defense response to other organismGO:0098542170.021
nucleotide metabolic processGO:00091172790.021
regulation of catabolic processGO:00098941130.021
purine ribonucleotide catabolic processGO:00091541360.021
immunoglobulin mediated immune responseGO:001606440.021
response to toxic substanceGO:00096361330.020
tissue developmentGO:00098882520.020
response to glucoseGO:00097491360.020
cell adhesion mediated by integrinGO:003362710.020
macrophage chemotaxisGO:004824620.020
oligopeptide transportGO:000685740.020
macromolecule catabolic processGO:0009057580.020
regulation of neuron apoptotic processGO:0043523830.020
regulation of transcription dna templatedGO:00063553740.020
response to metal ionGO:00100382530.020
cellular response to endogenous stimulusGO:00714953770.020
positive regulation of lipid kinase activityGO:009021820.019
positive regulation of cell proliferationGO:00082842490.019
positive regulation of cell developmentGO:00107201760.019
leukocyte migrationGO:0050900380.019
metanephric nephron tubule epithelial cell differentiationGO:007225710.019
agingGO:00075682410.019
cellular response to oxidative stressGO:0034599760.019
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000334020.018
reproductionGO:00000032450.018
nephron tubule epithelial cell differentiationGO:007216010.018
tyrosine phosphorylation of stat1 proteinGO:004250830.018
positive regulation of signalingGO:00230562700.018
cellular chemical homeostasisGO:00550822470.018
regulation of intracellular signal transductionGO:19025312180.018
purine nucleotide metabolic processGO:00061632290.018
positive regulation of biosynthetic processGO:00098913190.018
divalent metal ion transportGO:00708381320.018
carbohydrate derivative metabolic processGO:19011353460.018
negative regulation of homeostatic processGO:0032845470.018
response to amino acidGO:0043200750.018
regulation of lymphocyte migrationGO:200040110.017
negative regulation of cell deathGO:00605482290.017
negative regulation of leukocyte mediated cytotoxicityGO:000191150.017
response to temperature stimulusGO:0009266940.017
multicellular organismal reproductive processGO:00486092330.017
response to oxidative stressGO:00069791860.017
carboxylic acid metabolic processGO:00197522890.017
gamete generationGO:00072761240.017
regulation of cell proliferationGO:00421273590.017
divalent inorganic cation transportGO:00725111340.017
programmed cell deathGO:00125013920.017
cell migrationGO:00164771970.017
learning or memoryGO:0007611900.017
central nervous system developmentGO:00074173110.017
regulation of anatomical structure sizeGO:00900661350.016
negative regulation of multicellular organismal processGO:00512412030.016
antigen processing and presentation of endogenous peptide antigenGO:000248310.016
regulation of interleukin 1 secretionGO:005070430.016
sex differentiationGO:00075481130.016
cell projection organizationGO:00300303020.016
regulation of nucleic acid templated transcriptionGO:19035063800.016
biological adhesionGO:00226101100.016
negative regulation of catalytic activityGO:00430861030.016
cell type specific apoptotic processGO:00972851340.016
positive regulation of interferon gamma productionGO:003272920.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
intracellular receptor signaling pathwayGO:0030522350.015
positive regulation of nucleic acid templated transcriptionGO:19035081970.015
blood circulationGO:00080151830.015
cellular nitrogen compound catabolic processGO:00442701630.015
negative regulation of cell proliferationGO:00082851190.015
cellular response to molecule of fungal originGO:007122610.015
positive regulation of cell communicationGO:00106472710.015
response to heatGO:0009408600.015
gastrulationGO:000736920.015
negative regulation of cellular amine metabolic processGO:003323930.015
single organism reproductive processGO:00447022970.015
reactive oxygen species metabolic processGO:0072593370.014
development of primary sexual characteristicsGO:00451371070.014
negative regulation of neuron deathGO:1901215690.014
cellular response to steroid hormone stimulusGO:0071383930.014
glucose homeostasisGO:0042593750.014
positive regulation of homotypic cell cell adhesionGO:003411220.014
cellular response to lipidGO:00713962010.014
oxidation reduction processGO:00551143040.014
muscle system processGO:00030121150.014
interferon gamma productionGO:003260930.014
platelet aggregationGO:007052740.014
response to ammonium ionGO:0060359710.014
negative regulation of cellular component organizationGO:0051129830.014
regulation of kinase activityGO:00435491170.014
ncrna processingGO:003447030.014
lymphocyte migrationGO:007267630.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460130.014
startle responseGO:000196420.014
regulation of tube sizeGO:0035150890.014
positive regulation of cellular component organizationGO:00511302000.014
vascular process in circulatory systemGO:0003018960.014
cellular response to lipopolysaccharideGO:0071222550.014
negative regulation of phosphorus metabolic processGO:0010563800.014
regulation of necroptotic processGO:006054420.013
cell adhesionGO:00071551100.013
response to peptideGO:19016522920.013
neuron apoptotic processGO:0051402880.013
sequestering of metal ionGO:005123890.013
positive regulation of smooth muscle cell migrationGO:0014911270.013
positive regulation of fc receptor mediated stimulatory signaling pathwayGO:006036910.013
regulation of lipid metabolic processGO:0019216680.013
positive regulation of antigen processing and presentationGO:000257910.013
eye morphogenesisGO:004859240.013
regulation of nervous system developmentGO:00519602640.013
negative regulation of developmental processGO:00510931250.013
regulation of intracellular transportGO:0032386650.013
proteolysisGO:00065081750.013
glutathione transportGO:003463520.013
calcium ion transportGO:00068161310.013
neuron differentiationGO:00301823680.013
ear developmentGO:0043583210.013
negative regulation of g protein coupled receptor protein signaling pathwayGO:0045744150.013
regulation of neuron projection developmentGO:00109751610.013
cellular response to ketoneGO:1901655510.013
regulation of transferase activityGO:00513381230.012
positive regulation of purine nucleotide catabolic processGO:0033123530.012
cellular protein localizationGO:00346131220.012
negative regulation of neuron apoptotic processGO:0043524450.012
positive regulation of nucleotide metabolic processGO:0045981910.012
regulation of neuron differentiationGO:00456642080.012
positive regulation of apoptotic processGO:00430651540.012
cellular response to acid chemicalGO:0071229750.012
negative regulation of cell differentiationGO:0045596990.012
response to vitamin dGO:0033280340.012
epithelial cell differentiation involved in kidney developmentGO:003585030.012
organelle organizationGO:00069962660.012
chemotaxisGO:0006935660.012
regulation of homeostatic processGO:00328441010.012
regulation of actin cytoskeleton organizationGO:0032956300.012
embryonic axis specificationGO:000057810.012
erbb signaling pathwayGO:0038127230.012
negative regulation of phosphate metabolic processGO:0045936800.012
cellular response to glucose stimulusGO:0071333650.012
negative regulation of calcium ion importGO:009028120.012
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.012
t cell receptor signaling pathwayGO:005085210.012
embryonic pattern specificationGO:000988010.012
positive regulation of phosphorus metabolic processGO:00105622620.012
memoryGO:0007613540.012
macromolecule localizationGO:00330362520.011
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
axis specificationGO:000979840.011
cognitionGO:0050890920.011
inner ear developmentGO:0048839210.011
rho protein signal transductionGO:0007266110.011
positive regulation of neuron projection developmentGO:0010976990.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
nucleic acid templated transcriptionGO:00976593790.011
regulation of rna biosynthetic processGO:20011413810.011
olfactory behaviorGO:004204820.011
nuclear transportGO:0051169490.011
regulation of rna metabolic processGO:00512523910.011
developmental process involved in reproductionGO:00030061590.011
nitrogen compound transportGO:00717052290.011
tumor necrosis factor mediated signaling pathwayGO:003320940.011
cellular protein complex assemblyGO:0043623440.011
activation of protein kinase activityGO:0032147470.011
rna biosynthetic processGO:00327743800.011
regulation of blood vessel sizeGO:0050880890.011
cellular response to hydrogen peroxideGO:0070301420.011
sex determinationGO:000753020.011
cellular response to hexose stimulusGO:0071331650.011
positive regulation of hydrolase activityGO:0051345860.011
protein homooligomerizationGO:0051260910.011
peptidyl tyrosine modificationGO:0018212720.011
positive regulation of developmental processGO:00510942830.011
leukocyte differentiationGO:0002521300.011
cellular response to dexamethasone stimulusGO:0071549360.010
regulation of notch signaling pathwayGO:000859330.010
regulation of platelet aggregationGO:009033010.010
regulation of phosphate metabolic processGO:00192203490.010
cell motilityGO:00488702020.010
response to interleukin 1GO:0070555550.010
male mating behaviorGO:006017930.010
axon developmentGO:0061564960.010
salivary gland developmentGO:000743130.010
regulation of cell differentiationGO:00455953200.010
positive regulation of leukocyte migrationGO:0002687210.010
regulation of mrna 3 end processingGO:003144010.010
regulation of signal transductionGO:00099663180.010
positive regulation of macromolecule biosynthetic processGO:00105572470.010

RT1-EC2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.105
severe combined immunodeficiencyDOID:62700.105
disease of anatomical entityDOID:700.105
combined t cell and b cell immunodeficiencyDOID:62800.105
primary immunodeficiency diseaseDOID:61200.105
nervous system diseaseDOID:86300.012