Rattus norvegicus

22 known processes

Orai1

ORAI calcium release-activated calcium modulator 1

(Aliases: RGD1311873)

Orai1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of molecular functionGO:00650093980.479
apoptotic processGO:00069153810.268
positive regulation of cell communicationGO:00106472710.238
transcription dna templatedGO:00063513770.187
regulation of protein metabolic processGO:00512462890.186
protein localizationGO:00081041910.178
programmed cell deathGO:00125013920.159
regulation of apoptotic processGO:00429813350.124
regulation of programmed cell deathGO:00430673410.123
regulation of cellular localizationGO:00603412630.119
macromolecule localizationGO:00330362520.116
positive regulation of response to stimulusGO:00485842850.114
positive regulation of biosynthetic processGO:00098913190.111
rna metabolic processGO:00160704060.109
positive regulation of cellular biosynthetic processGO:00313282950.106
regulation of intracellular signal transductionGO:19025312180.106
positive regulation of molecular functionGO:00440932300.106
immune system processGO:00023762040.104
signal transduction by phosphorylationGO:00230141440.094
response to bacteriumGO:00096172000.092
regulation of phosphate metabolic processGO:00192203490.092
positive regulation of nitrogen compound metabolic processGO:00511733340.091
nucleic acid templated transcriptionGO:00976593790.090
negative regulation of metabolic processGO:00098923310.089
cellular component assemblyGO:00226073600.087
regulation of transcription dna templatedGO:00063553740.087
regulation of signal transductionGO:00099663180.080
response to inorganic substanceGO:00100353770.080
leukocyte activationGO:0045321760.077
regulation of rna biosynthetic processGO:20011413810.076
positive regulation of signalingGO:00230562700.076
intracellular signal transductionGO:00355563140.074
regulation of catalytic activityGO:00507903040.074
protein transportGO:00150311320.073
anatomical structure morphogenesisGO:00096532980.069
agingGO:00075682410.069
positive regulation of nucleobase containing compound metabolic processGO:00459353190.069
establishment of protein localizationGO:00451841410.068
neuron differentiationGO:00301823680.067
regulation of cell differentiationGO:00455953200.067
positive regulation of transcription dna templatedGO:00458931970.066
positive regulation of gene expressionGO:00106282440.066
cellular macromolecule localizationGO:00707271220.063
positive regulation of macromolecule biosynthetic processGO:00105572470.063
regulation of phosphorylationGO:00423252480.063
peptide biosynthetic processGO:004304330.063
regulation of multicellular organismal developmentGO:20000263760.062
response to biotic stimulusGO:00096072260.060
regulation of fat cell differentiationGO:004559830.060
protein phosphorylationGO:00064683450.060
positive regulation of signal transductionGO:00099671750.060
cation transportGO:00068123820.059
response to other organismGO:00517072200.059
positive regulation of rna biosynthetic processGO:19026801970.057
regulation of neurogenesisGO:00507672470.056
reproductive processGO:00224143720.056
negative regulation of macromolecule metabolic processGO:00106052600.056
ion transmembrane transportGO:00342203650.056
rna biosynthetic processGO:00327743800.055
positive regulation of multicellular organismal processGO:00512403870.055
neuron developmentGO:00486662860.054
cation transmembrane transportGO:00986552630.052
positive regulation of intracellular signal transductionGO:19025331380.051
negative regulation of cellular metabolic processGO:00313242810.050
regulation of cellular protein metabolic processGO:00322682670.050
immune responseGO:00069551040.048
positive regulation of transportGO:00510502450.047
Human
negative regulation of molecular functionGO:00440921330.046
regulation of nucleic acid templated transcriptionGO:19035063800.045
single organism cellular localizationGO:19025801020.045
secretionGO:00469033070.045
negative regulation of gene expressionGO:00106291990.045
regulation of cell developmentGO:00602842630.045
positive regulation of phosphorus metabolic processGO:00105622620.044
positive regulation of nucleic acid templated transcriptionGO:19035081970.044
regulation of odontogenesis of dentin containing toothGO:004248720.043
regulation of cell proliferationGO:00421273590.043
positive regulation of secretionGO:00510471400.042
inorganic cation transmembrane transportGO:00986622020.042
positive regulation of cell deathGO:00109421840.042
positive regulation of rna metabolic processGO:00512542030.042
ensheathment of neuronsGO:0007272400.042
positive regulation of phosphate metabolic processGO:00459372620.041
inflammatory responseGO:00069541500.040
response to mechanical stimulusGO:00096121340.040
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.039
cellular response to endogenous stimulusGO:00714953770.039
response to lipopolysaccharideGO:00324961910.039
positive regulation of secretion by cellGO:19035321280.039
regulation of immune system processGO:00026821230.039
regulation of rna metabolic processGO:00512523910.039
positive regulation of phosphorylationGO:00423271770.038
positive regulation of catalytic activityGO:00430851840.038
metal ion transportGO:00300012890.038
multicellular organismal signalingGO:0035637440.037
regulation of phosphorus metabolic processGO:00511743490.037
regulation of protein transportGO:0051223680.037
store operated calcium entryGO:000211520.037
response to nutrient levelsGO:00316673700.037
positive regulation of nervous system developmentGO:00519621780.036
cell type specific apoptotic processGO:00972851340.036
regulation of apoptotic signaling pathwayGO:2001233130.035
response to extracellular stimulusGO:00099913800.035
regulation of mapk cascadeGO:00434081160.035
homeostatic processGO:00425923310.035
negative regulation of transportGO:00510511360.035
cellular component biogenesisGO:00440853680.035
negative regulation of signalingGO:00230571570.035
protein oligomerizationGO:00512591910.034
negative regulation of protein metabolic processGO:00512481140.034
cellular response to cytokine stimulusGO:00713451270.033
regulation of kinase activityGO:00435491170.033
single organism membrane organizationGO:0044802740.033
axon ensheathmentGO:0008366400.032
neuron apoptotic processGO:0051402880.032
protein complex assemblyGO:00064612630.032
response to growth factorGO:00708481890.032
response to metal ionGO:00100382530.032
regulation of transcription from rna polymerase ii promoterGO:00063572340.032
cellular amino acid metabolic processGO:00065201070.032
developmental process involved in reproductionGO:00030061590.032
regulation of nervous system developmentGO:00519602640.031
regulation of leukocyte activationGO:0002694450.031
neuronal action potentialGO:0019228350.031
neuron projection developmentGO:00311752730.031
regulation of metal ion transportGO:00109591180.031
Human
regulation of proteasomal protein catabolic processGO:006113640.031
cellular amide metabolic processGO:0043603440.031
negative regulation of cellular protein metabolic processGO:00322691060.031
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.031
regulation of cellular amine metabolic processGO:003323880.030
oxoacid metabolic processGO:00434362900.030
regulation of neuron differentiationGO:00456642080.030
positive regulation of cell differentiationGO:00455972170.030
response to oxidative stressGO:00069791860.029
transmembrane transportGO:00550854120.029
cellular response to peptide hormone stimulusGO:00713751200.029
transmission of nerve impulseGO:0019226420.029
regulation of protein localizationGO:0032880810.029
transcription from rna polymerase ii promoterGO:00063662520.029
positive regulation of protein phosphorylationGO:00019341350.029
regulation of cellular amino acid metabolic processGO:000652120.028
secretion by cellGO:00329402480.028
sensory organ developmentGO:0007423740.028
neuron deathGO:00709971270.028
regulation of transmembrane transporter activityGO:0022898490.027
lymphocyte activationGO:0046649430.027
cellular amine metabolic processGO:0044106380.027
action potentialGO:0001508540.027
cellular protein localizationGO:00346131220.027
regulation of calcium ion transportGO:0051924770.027
Human
regulation of cellular component organizationGO:00511283680.027
inorganic ion transmembrane transportGO:00986602290.027
myelinationGO:0042552390.027
positive regulation of cellular protein metabolic processGO:00322701670.027
purine containing compound metabolic processGO:00725212530.027
negative regulation of cell communicationGO:00106481580.026
response to cytokineGO:00340972150.026
lipid transportGO:0006869610.026
anion transportGO:00068201780.026
asymmetric protein localizationGO:000810520.026
brain developmentGO:00074202470.026
maintenance of locationGO:0051235170.025
regulation of response to stressGO:00801341260.025
regulation of ion transmembrane transporter activityGO:0032412480.025
regulation of membrane potentialGO:00423911100.025
cellular response to nitrogen compoundGO:19016992100.025
response to estrogenGO:00436272320.025
positive regulation of cellular amine metabolic processGO:003324030.025
proteolysisGO:00065081750.025
regulation of ion transportGO:00432692450.025
Human
ion homeostasisGO:00508012120.025
negative regulation of nitrogen compound metabolic processGO:00511721610.025
positive regulation of mapk cascadeGO:0043410920.024
cell projection organizationGO:00300303020.024
intracellular protein transportGO:0006886790.024
regulation of system processGO:00440572080.024
chemical homeostasisGO:00488782920.024
macromolecular complex assemblyGO:00650032730.024
regulation of cellular ketone metabolic processGO:0010565270.024
cation homeostasisGO:00550801950.024
lipid metabolic processGO:00066292830.024
cellular response to molecule of bacterial originGO:0071219560.024
cellular response to growth factor stimulusGO:00713631620.024
head developmentGO:00603222470.023
negative regulation of rna metabolic processGO:00512531230.023
positive regulation of apoptotic processGO:00430651540.023
carbohydrate derivative catabolic processGO:19011361470.023
response to tumor necrosis factorGO:0034612560.023
calcium ion transmembrane transportGO:0070588700.023
negative regulation of biosynthetic processGO:00098901680.023
regulation of secretion by cellGO:19035302080.023
amine metabolic processGO:0009308380.023
muscle system processGO:00030121150.022
cellular response to stressGO:00335542690.022
cellular response to organonitrogen compoundGO:00714171970.022
positive regulation of protein metabolic processGO:00512471780.022
cell cell signalingGO:00072673350.022
mapk cascadeGO:00001651400.022
regulation of protein kinase activityGO:00458591050.022
regulation of protein phosphorylationGO:00019321830.021
positive regulation of cell developmentGO:00107201760.021
multi organism reproductive processGO:00447032620.021
regulation of establishment of protein localizationGO:0070201690.021
organic acid metabolic processGO:00060822920.021
cellular response to tumor necrosis factorGO:0071356460.021
organonitrogen compound biosynthetic processGO:19015661670.021
hormone metabolic processGO:0042445690.020
protein modification by small protein conjugation or removalGO:0070647350.020
negative regulation of transcription dna templatedGO:00458921160.020
female pregnancyGO:00075651220.020
cellular response to abiotic stimulusGO:0071214850.020
insulin receptor signaling pathwayGO:0008286240.020
regulation of stress activated mapk cascadeGO:0032872230.020
positive regulation of protein transportGO:0051222410.020
lipid localizationGO:0010876620.020
small gtpase mediated signal transductionGO:0007264360.019
purine containing compound catabolic processGO:00725231380.019
salivary gland morphogenesisGO:000743510.019
peptidyl amino acid modificationGO:00181931260.019
cellular divalent inorganic cation homeostasisGO:00725031620.019
regulation of odontogenesisGO:004248140.019
circulatory system processGO:00030131830.019
lipid storageGO:001991510.019
negative regulation of apoptotic processGO:00430661810.019
vesicle mediated transportGO:00161921810.019
purine nucleotide metabolic processGO:00061632290.019
salivary gland developmentGO:000743130.019
response to external biotic stimulusGO:00432072210.019
response to peptideGO:19016522920.019
cellular ketone metabolic processGO:0042180510.019
positive regulation of transferase activityGO:0051347810.018
intracellular receptor signaling pathwayGO:0030522350.018
regulation of transferase activityGO:00513381230.018
macromolecular complex subunit organizationGO:00439333390.018
regulation of muscle contractionGO:0006937530.018
protein complex biogenesisGO:00702712630.018
divalent inorganic cation homeostasisGO:00725071650.018
blood circulationGO:00080151830.018
carboxylic acid metabolic processGO:00197522890.018
metal ion homeostasisGO:00550651860.018
protein targetingGO:0006605610.018
divalent metal ion transportGO:00708381320.017
negative regulation of response to stimulusGO:00485851550.017
protein processingGO:0016485680.017
regulation of hormone levelsGO:00108171870.017
positive regulation of cell proliferationGO:00082842490.017
actin filament based processGO:0030029860.017
cellular ion homeostasisGO:00068731840.016
regulation of sequence specific dna binding transcription factor activityGO:0051090350.016
embryonic pattern specificationGO:000988010.016
axis specificationGO:000979840.016
regulation of immune responseGO:0050776550.016
multicellular organismal reproductive processGO:00486092330.016
regulation of cell activationGO:0050865500.016
positive regulation of developmental processGO:00510942830.016
positive regulation of neuron differentiationGO:00456661260.016
cell activationGO:0001775970.016
reproductionGO:00000032450.016
cellular lipid metabolic processGO:00442552080.016
organic hydroxy compound transportGO:0015850770.016
calcium ion homeostasisGO:00550741620.015
cellular response to external stimulusGO:00714961180.015
ribonucleotide catabolic processGO:00092611360.015
embryo developmentGO:0009790490.015
cellular catabolic processGO:00442482950.015
cellular chemical homeostasisGO:00550822470.015
purine ribonucleotide metabolic processGO:00091502270.015
regulation of blood circulationGO:19035221100.015
positive regulation of programmed cell deathGO:00430681570.015
positive regulation of protein kinase activityGO:0045860730.015
positive regulation of protein modification processGO:00314011420.015
regulation of ion transmembrane transportGO:00347651210.015
membrane organizationGO:0061024940.015
sensory perceptionGO:00076001010.015
regulation of secretionGO:00510462240.015
organic substance catabolic processGO:19015753160.015
response to nutrientGO:00075842480.015
cellular calcium ion homeostasisGO:00068741600.015
single organism intracellular transportGO:19025821660.014
apoptotic signaling pathwayGO:0097190270.014
regulation of anatomical structure morphogenesisGO:00226031410.014
negative regulation of cell differentiationGO:0045596990.014
cellular response to oxidative stressGO:0034599760.014
mirna metabolic processGO:001058610.014
negative regulation of phosphorus metabolic processGO:0010563800.014
ribonucleotide metabolic processGO:00092592310.014
negative regulation of catalytic activityGO:00430861030.014
cellular response to oxygen containing compoundGO:19017013860.014
synaptic transmissionGO:00072682350.014
regulation of cation channel activityGO:2001257230.014
cellular response to mechanical stimulusGO:0071260480.014
negative regulation of programmed cell deathGO:00430691830.014
regulation of catabolic processGO:00098941130.014
negative regulation of developmental processGO:00510931250.014
activation of immune responseGO:0002253260.014
cellular response to insulin stimulusGO:0032869810.014
regulation of transmembrane transportGO:00347621220.014
nucleoside phosphate catabolic processGO:19012921400.014
localization of cellGO:00516742020.014
carboxylic acid transportGO:00469421150.014
regulation of muscle system processGO:0090257790.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
response to radiationGO:00093141370.013
negative regulation of protein maturationGO:1903318470.013
cell adhesionGO:00071551100.013
regulation of protein import into nucleusGO:0042306240.013
response to ketoneGO:19016541820.013
negative regulation of protein modification processGO:0031400520.013
neurological system processGO:00508772190.013
multi multicellular organism processGO:00447061380.013
single organism carbohydrate metabolic processGO:00447231180.013
response to reactive oxygen speciesGO:00003021200.013
regulation of cell projection organizationGO:00313441750.013
cellular homeostasisGO:00197252520.013
negative regulation of cellular biosynthetic processGO:00313271610.013
catabolic processGO:00090563510.013
carbohydrate derivative metabolic processGO:19011353460.013
extrinsic apoptotic signaling pathwayGO:0097191100.013
negative regulation of cell deathGO:00605482290.013
defense responseGO:00069521940.013
regulation of cellular component movementGO:00512701500.013
tube developmentGO:0035295890.013
regulation of transporter activityGO:0032409500.013
intracellular transportGO:00469071850.013
peptide metabolic processGO:0006518320.012
nucleobase containing compound catabolic processGO:00346551520.012
nitrogen compound transportGO:00717052290.012
eye developmentGO:0001654500.012
organ morphogenesisGO:0009887750.012
response to ethanolGO:00454711620.012
positive regulation of cellular component organizationGO:00511302000.012
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.012
regulation of intracellular protein transportGO:0033157340.012
jnk cascadeGO:0007254280.012
glycosyl compound metabolic processGO:19016571820.012
negative regulation of insulin receptor signaling pathwayGO:0046627100.012
positive regulation of cytokine productionGO:0001819420.012
stress activated protein kinase signaling cascadeGO:0031098370.012
regulation of jnk cascadeGO:0046328190.012
protein heterooligomerizationGO:0051291890.012
regulation of neuron apoptotic processGO:0043523830.012
response to temperature stimulusGO:0009266940.012
purine ribonucleoside metabolic processGO:00461281680.012
cellular cation homeostasisGO:00300031800.012
response to progesteroneGO:0032570480.012
regulation of extrinsic apoptotic signaling pathwayGO:200123670.012
ras protein signal transductionGO:0007265290.012
regulation of homeostatic processGO:00328441010.011
camera type eye developmentGO:0043010480.011
regulation of cellular response to stressGO:0080135490.011
organophosphate catabolic processGO:00464341480.011
positive regulation of jnk cascadeGO:0046330130.011
circulatory system developmentGO:00723591340.011
cellular response to peptideGO:19016531330.011
response to acid chemicalGO:00011012220.011
nucleoside metabolic processGO:00091161790.011
regulation of lymphocyte activationGO:0051249340.011
positive regulation of ion transportGO:0043270940.011
Human
positive regulation of i kappab kinase nf kappab signalingGO:004312380.011
chromosome segregationGO:000705920.011
positive regulation of triglyceride biosynthetic processGO:001086740.011
regulation of blood vessel sizeGO:0050880890.011
organophosphate metabolic processGO:00196373700.011
positive regulation of intracellular protein transportGO:0090316200.011
dephosphorylationGO:0016311980.011
single organism reproductive processGO:00447022970.011
organic acid transportGO:00158491160.011
response to interleukin 1GO:0070555550.011
protein localization to organelleGO:0033365570.011
regulation of vesicle mediated transportGO:0060627810.011
erbb signaling pathwayGO:0038127230.011
calcium ion transportGO:00068161310.011
response to peptide hormoneGO:00434342780.011
negative regulation of nervous system developmentGO:0051961790.011
cell part morphogenesisGO:00329901230.011
detection of stimulusGO:0051606240.011
regulation of locomotionGO:00400121480.011
divalent inorganic cation transportGO:00725111340.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
cellular metal ion homeostasisGO:00068751720.011
heterocycle catabolic processGO:00467001670.011
monovalent inorganic cation transportGO:00156721720.011
endomembrane system organizationGO:0010256480.011
response to woundingGO:00096112540.011
stress activated mapk cascadeGO:0051403350.011
biological adhesionGO:00226101100.011
positive regulation of kinase activityGO:0033674770.011
regulation of protein targetingGO:1903533280.010
establishment of protein localization to organelleGO:0072594440.010
positive regulation of neurogenesisGO:00507691650.010
muscle contractionGO:0006936880.010
nucleobase containing small molecule metabolic processGO:00550863160.010
response to corticosteroidGO:00319602350.010
response to osmotic stressGO:0006970420.010
negative regulation of multicellular organismal processGO:00512412030.010
cell motilityGO:00488702020.010
vascular process in circulatory systemGO:0003018960.010
cytoplasmic transportGO:00164821150.010
actin cytoskeleton organizationGO:0030036730.010
negative regulation of protein phosphorylationGO:0001933440.010
purine nucleotide catabolic processGO:00061951360.010
regulation of neuron deathGO:19012141150.010
organic cyclic compound catabolic processGO:19013611750.010
amino acid transportGO:0006865700.010
single organism biosynthetic processGO:00447113420.010

Orai1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
nervous system diseaseDOID:86300.029
musculoskeletal system diseaseDOID:1700.026
muscular diseaseDOID:008000000.016
myopathyDOID:42300.015
muscle tissue diseaseDOID:6600.015
central nervous system diseaseDOID:33100.010