Rattus norvegicus

49 known processes

Cubn

cubilin (intrinsic factor-cobalamin receptor)

(Aliases: GP280,IFCR,MGA1)

Cubn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to external biotic stimulusGO:00432072210.341
positive regulation of multicellular organismal processGO:00512403870.241
inorganic ion transmembrane transportGO:00986602290.198
transmembrane transportGO:00550854120.177
reproductive processGO:00224143720.171
cellular response to endogenous stimulusGO:00714953770.169
anion transportGO:00068201780.165
response to other organismGO:00517072200.145
cellular response to oxygen containing compoundGO:19017013860.141
fractalkine metabolic processGO:005075630.138
protein oligomerizationGO:00512591910.134
cation transportGO:00068123820.129
response to peptideGO:19016522920.123
organic acid transportGO:00158491160.122
response to growth factorGO:00708481890.121
epithelium developmentGO:0060429960.120
response to peptide hormoneGO:00434342780.118
single organism reproductive processGO:00447022970.112
cellular component biogenesisGO:00440853680.108
cellular ketone metabolic processGO:0042180510.104
response to biotic stimulusGO:00096072260.103
circulatory system processGO:00030131830.100
organic anion transportGO:00157111320.097
rhythmic processGO:00485111560.097
central nervous system developmentGO:00074173110.095
positive regulation of phosphate metabolic processGO:00459372620.094
response to nutrient levelsGO:00316673700.092
regulation of multicellular organismal developmentGO:20000263760.091
positive regulation of biosynthetic processGO:00098913190.090
cellular response to growth factor stimulusGO:00713631620.089
blood circulationGO:00080151830.089
regulation of signal transductionGO:00099663180.089
sodium ion transmembrane transportGO:0035725670.087
response to insulinGO:00328681330.087
oxoacid metabolic processGO:00434362900.085
cellular response to organic cyclic compoundGO:00714072020.084
response to lipopolysaccharideGO:00324961910.081
carboxylic acid transportGO:00469421150.080
multi organism reproductive processGO:00447032620.080
regulation of phosphorus metabolic processGO:00511743490.080
response to purine containing compoundGO:00140741260.079
response to molecule of bacterial originGO:00022371940.078
ion transmembrane transportGO:00342203650.078
transmission of nerve impulseGO:0019226420.078
regulation of catalytic activityGO:00507903040.077
regulation of cell differentiationGO:00455953200.077
multicellular organism reproductionGO:00325042330.077
positive regulation of developmental processGO:00510942830.076
regulation of hormone levelsGO:00108171870.076
head developmentGO:00603222470.076
protein complex assemblyGO:00064612630.074
multicellular organismal reproductive processGO:00486092330.074
positive regulation of cellular biosynthetic processGO:00313282950.074
anion transmembrane transportGO:0098656770.074
regulation of cell proliferationGO:00421273590.072
macromolecular complex subunit organizationGO:00439333390.072
positive regulation of molecular functionGO:00440932300.070
regulation of molecular functionGO:00650093980.068
small molecule biosynthetic processGO:00442831240.066
organonitrogen compound biosynthetic processGO:19015661670.065
positive regulation of signalingGO:00230562700.065
regulation of rna metabolic processGO:00512523910.065
homeostatic processGO:00425923310.065
positive regulation of nucleobase containing compound metabolic processGO:00459353190.064
regulation of cellular ketone metabolic processGO:0010565270.060
regulation of phosphate metabolic processGO:00192203490.059
macromolecular complex assemblyGO:00650032730.059
cellular response to lipidGO:00713962010.058
regulation of rna biosynthetic processGO:20011413810.058
negative regulation of cell deathGO:00605482290.056
cellular response to hormone stimulusGO:00328702470.056
organic acid metabolic processGO:00060822920.056
amine metabolic processGO:0009308380.056
chemical homeostasisGO:00488782920.055
response to toxic substanceGO:00096361330.055
neuronal action potentialGO:0019228350.054
response to acid chemicalGO:00011012220.054
brain developmentGO:00074202470.052
positive regulation of response to stimulusGO:00485842850.052
eye morphogenesisGO:004859240.052
regulation of blood pressureGO:0008217830.051
cellular amino acid metabolic processGO:00065201070.051
neurological system processGO:00508772190.049
cellular response to alcoholGO:0097306870.049
regulation of protein metabolic processGO:00512462890.048
reproductive structure developmentGO:00486081280.048
gonad developmentGO:00084061040.047
fat cell proliferationGO:007034120.047
purine containing compound biosynthetic processGO:0072522850.047
tissue developmentGO:00098882520.046
positive regulation of transportGO:00510502450.045
multi multicellular organism processGO:00447061380.045
intracellular signal transductionGO:00355563140.045
response to campGO:0051591910.044
regulation of blood vessel sizeGO:0050880890.044
epithelial cell differentiationGO:0030855710.044
response to oxygen levelsGO:00704822650.044
leukocyte differentiationGO:0002521300.044
gland developmentGO:00487321550.044
insecticide metabolic processGO:001714340.044
amino acid transportGO:0006865700.043
regenerationGO:00310991630.043
regulation of ion transportGO:00432692450.043
regulation of membrane potentialGO:00423911100.043
response to organophosphorusGO:00466831020.042
single organism biosynthetic processGO:00447113420.042
positive regulation of cellular amino acid metabolic processGO:004576410.041
response to bacteriumGO:00096172000.041
regulation of system processGO:00440572080.041
monovalent inorganic cation transportGO:00156721720.041
macromolecule localizationGO:00330362520.040
regulation of phosphorylationGO:00423252480.040
cellular chemical homeostasisGO:00550822470.040
protein phosphorylationGO:00064683450.040
regulation of protein phosphorylationGO:00019321830.039
cardiovascular system developmentGO:00723581340.039
regulation of protein modification processGO:00313991940.039
carboxylic acid metabolic processGO:00197522890.039
ovulation cycleGO:0042698670.039
behaviorGO:00076102050.039
protein complex subunit organizationGO:00718223020.038
glial cell differentiationGO:0010001650.038
response to vitaminGO:00332731310.038
response to estrogenGO:00436272320.038
vascular process in circulatory systemGO:0003018960.038
regulation of lymphocyte chemotaxisGO:190162310.037
cation transmembrane transportGO:00986552630.037
regulation of cellular protein metabolic processGO:00322682670.037
response to glucocorticoidGO:00513842230.036
positive regulation of cellular amine metabolic processGO:003324030.036
organophosphate biosynthetic processGO:00904071430.036
rna metabolic processGO:00160704060.036
response to antibioticGO:0046677390.036
regulation of cellular amino acid metabolic processGO:000652120.036
anatomical structure morphogenesisGO:00096532980.035
regulation of nervous system developmentGO:00519602640.035
rna biosynthetic processGO:00327743800.035
nitrogen compound transportGO:00717052290.035
regulation of cellular amine metabolic processGO:003323880.035
nucleotide biosynthetic processGO:0009165980.035
cellular ion homeostasisGO:00068731840.034
response to ketoneGO:19016541820.034
apoptotic processGO:00069153810.034
cellular amine metabolic processGO:0044106380.034
regulation of apoptotic processGO:00429813350.034
regulation of secretionGO:00510462240.033
secretionGO:00469033070.033
purine ribonucleotide biosynthetic processGO:0009152810.033
sodium ion transportGO:0006814820.033
negative regulation of programmed cell deathGO:00430691830.033
nucleobase containing small molecule metabolic processGO:00550863160.033
response to corticosteroidGO:00319602350.033
cellular response to nitrogen compoundGO:19016992100.032
positive regulation of cell communicationGO:00106472710.032
female pregnancyGO:00075651220.032
cellular response to organonitrogen compoundGO:00714171970.032
nucleoside phosphate metabolic processGO:00067532830.032
positive regulation of phosphorus metabolic processGO:00105622620.032
axon ensheathmentGO:0008366400.031
cyclic nucleotide biosynthetic processGO:0009190630.031
tube developmentGO:0035295890.031
secretion by cellGO:00329402480.030
regulation of neurogenesisGO:00507672470.030
cellular response to extracellular stimulusGO:0031668730.030
lipid biosynthetic processGO:00086101280.030
purine containing compound metabolic processGO:00725212530.029
response to carbohydrateGO:00097431830.029
cellular response to ketoneGO:1901655510.029
cellular response to acid chemicalGO:0071229750.029
metal ion transportGO:00300012890.029
sensory organ developmentGO:0007423740.028
purine nucleotide biosynthetic processGO:0006164830.028
action potentialGO:0001508540.028
organophosphate metabolic processGO:00196373700.028
protein complex biogenesisGO:00702712630.028
nucleic acid templated transcriptionGO:00976593790.028
inorganic cation transmembrane transportGO:00986622020.028
positive regulation of cell deathGO:00109421840.028
response to glucoseGO:00097491360.028
regulation of cellular localizationGO:00603412630.028
proteolysisGO:00065081750.027
carbohydrate derivative metabolic processGO:19011353460.027
cellular response to stressGO:00335542690.027
t cell chemotaxisGO:001081820.027
regulation of cyclic nucleotide metabolic processGO:0030799510.027
positive regulation of nitrogen compound metabolic processGO:00511733340.026
neuron developmentGO:00486662860.026
cation homeostasisGO:00550801950.026
reproductionGO:00000032450.026
regulation of body fluid levelsGO:0050878900.026
ribonucleotide biosynthetic processGO:0009260850.026
oxidation reduction processGO:00551143040.025
positive regulation of secretion by cellGO:19035321280.025
cellular component assemblyGO:00226073600.025
ras protein signal transductionGO:0007265290.025
regulation of cell developmentGO:00602842630.025
positive regulation of cellular protein metabolic processGO:00322701670.025
response to dexamethasoneGO:0071548490.025
fat soluble vitamin biosynthetic processGO:004236220.025
organ regenerationGO:00311001010.024
agingGO:00075682410.024
negative regulation of metabolic processGO:00098923310.024
response to decreased oxygen levelsGO:00362932370.024
positive regulation of purine nucleotide metabolic processGO:1900544910.024
response to cytokineGO:00340972150.023
purine nucleotide metabolic processGO:00061632290.023
regulation of programmed cell deathGO:00430673410.023
nucleoside phosphate biosynthetic processGO:19012931020.023
cellular homeostasisGO:00197252520.023
vitamin d metabolic processGO:004235940.023
positive regulation of t cell migrationGO:200040610.023
multicellular organismal signalingGO:0035637440.022
positive regulation of protein modification processGO:00314011420.022
sex differentiationGO:00075481130.022
cellular response to peptide hormone stimulusGO:00713751200.022
regulation of intracellular signal transductionGO:19025312180.022
cell migrationGO:00164771970.022
negative regulation of molecular functionGO:00440921330.021
neuron differentiationGO:00301823680.021
cytokine biosynthetic processGO:004208930.021
immunoglobulin secretionGO:004830510.021
ensheathment of neuronsGO:0007272400.021
positive regulation of catalytic activityGO:00430851840.021
gliogenesisGO:0042063930.021
antibiotic transportGO:004289120.021
protein localizationGO:00081041910.021
regulation of t cell chemotaxisGO:001081910.021
vitamin transportGO:0051180140.021
small gtpase mediated signal transductionGO:0007264360.021
immunoglobulin mediated immune responseGO:001606440.020
negative regulation of signalingGO:00230571570.020
progesterone biosynthetic processGO:000670130.020
b cell activation involved in immune responseGO:000231210.020
response to metal ionGO:00100382530.020
positive regulation of ion transportGO:0043270940.020
membrane hyperpolarizationGO:0060081110.019
muscle system processGO:00030121150.019
protein homooligomerizationGO:0051260910.019
organic hydroxy compound biosynthetic processGO:1901617510.019
regulation of fat cell proliferationGO:007034410.019
circulatory system developmentGO:00723591340.019
choline transportGO:001587140.018
regulation of cellular component organizationGO:00511283680.018
circadian rhythmGO:0007623880.018
negative regulation of cellular metabolic processGO:00313242810.018
regulation of brown fat cell proliferationGO:007034710.018
negative regulation of transportGO:00510511360.018
regulation of lymphocyte migrationGO:200040110.018
programmed cell deathGO:00125013920.018
regulation of t cell migrationGO:200040410.018
developmental process involved in reproductionGO:00030061590.018
developmental inductionGO:003112820.018
response to hypoxiaGO:00016662310.018
calcitriol biosynthetic process from calciolGO:003637820.018
cellular response to gonadotropin stimulusGO:0071371170.018
lipid transportGO:0006869610.018
alcohol biosynthetic processGO:0046165380.018
lymphocyte chemotaxisGO:004824730.018
regulation of neuron differentiationGO:00456642080.018
alcohol metabolic processGO:0006066770.018
synaptic transmission glutamatergicGO:0035249330.018
regulation of cell motilityGO:20001451310.018
ion homeostasisGO:00508012120.018
regulation of cytokine biosynthetic processGO:004203530.018
response to activityGO:0014823730.018
ribonucleotide metabolic processGO:00092592310.018
cyclic nucleotide metabolic processGO:0009187800.018
regulation of response to woundingGO:1903034690.017
oligopeptide transportGO:000685740.017
positive regulation of brown fat cell proliferationGO:007034910.017
regulation of anatomical structure morphogenesisGO:00226031410.017
positive regulation of cell differentiationGO:00455972170.017
positive regulation of cyclic nucleotide metabolic processGO:0030801370.017
response to amino acidGO:0043200750.017
positive regulation of phosphorylationGO:00423271770.017
positive regulation of fat cell proliferationGO:007034610.017
cyclic purine nucleotide metabolic processGO:0052652620.017
circadian regulation of gene expressionGO:003292230.017
coronary vasculature morphogenesisGO:006097730.017
negative regulation of cell proliferationGO:00082851190.017
positive regulation of protein metabolic processGO:00512471780.017
positive regulation of behaviorGO:0048520380.016
liver developmentGO:0001889900.016
transcription dna templatedGO:00063513770.016
catabolic processGO:00090563510.016
negative regulation of multicellular organismal processGO:00512412030.016
regulation of transmembrane transporter activityGO:0022898490.016
regulation of response to external stimulusGO:00321011060.016
gastrulationGO:000736920.016
single organism behaviorGO:00447081300.016
defense responseGO:00069521940.016
positive regulation of cellular component organizationGO:00511302000.016
regulation of hydrolase activityGO:00513361430.016
cellular response to nutrient levelsGO:0031669600.016
epithelial cell proliferationGO:0050673540.016
response to inorganic substanceGO:00100353770.016
signal transduction involved in regulation of gene expressionGO:002301940.016
cytokine metabolic processGO:004210760.016
response to nicotineGO:0035094510.016
blood vessel developmentGO:0001568690.016
regulation of anatomical structure sizeGO:00900661350.016
negative regulation of cell communicationGO:00106481580.016
protein transportGO:00150311320.016
metal ion homeostasisGO:00550651860.016
negative regulation of macromolecule metabolic processGO:00106052600.015
testosterone biosynthetic processGO:006137050.015
immune system processGO:00023762040.015
ribose phosphate biosynthetic processGO:0046390870.015
regulation of cell migrationGO:00303341280.015
male sex differentiationGO:0046661640.015
regulation of transmembrane transportGO:00347621220.015
regulation of cyclic nucleotide biosynthetic processGO:0030802450.015
carbohydrate derivative biosynthetic processGO:19011371240.015
organ morphogenesisGO:0009887750.015
regulation of sodium ion transmembrane transporter activityGO:200064940.015
dopamine transportGO:0015872180.015
cellular response to transforming growth factor beta stimulusGO:0071560410.015
response to alkaloidGO:00432791320.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
locomotionGO:00400112370.015
ribose phosphate metabolic processGO:00196932350.015
regulation of transferase activityGO:00513381230.015
positive regulation of secretionGO:00510471400.015
positive regulation of intracellular signal transductionGO:19025331380.015
positive regulation of macromolecule biosynthetic processGO:00105572470.015
regulation of secretion by cellGO:19035302080.015
negative regulation of apoptotic processGO:00430661810.014
inner ear receptor cell differentiationGO:006011320.014
regulation of purine nucleotide metabolic processGO:19005421150.014
tissue regenerationGO:0042246360.014
macromolecule catabolic processGO:0009057580.014
positive regulation of renin secretion into blood streamGO:190013510.014
response to ammonium ionGO:0060359710.014
secondary alcohol metabolic processGO:190265220.014
response to monosaccharideGO:00342841590.014
response to woundingGO:00096112540.014
regulation of cellular component movementGO:00512701500.014
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.014
telencephalon developmentGO:0021537620.014
calcium ion transportGO:00068161310.014
protein catabolic processGO:0030163300.014
positive regulation of nervous system developmentGO:00519621780.014
rho protein signal transductionGO:0007266110.014
blood vessel morphogenesisGO:0048514580.013
cellular calcium ion homeostasisGO:00068741600.013
cellular response to peptideGO:19016531330.013
brown fat cell proliferationGO:007034220.013
vasculature developmentGO:0001944700.013
regulation of nucleotide biosynthetic processGO:0030808470.013
calcium ion homeostasisGO:00550741620.013
regulation of ion transmembrane transportGO:00347651210.013
sleepGO:0030431300.013
gamete generationGO:00072761240.013
negative regulation of rna metabolic processGO:00512531230.013
regulation of renin secretion into blood streamGO:190013310.013
regulation of isotype switchingGO:004519110.013
positive regulation of angiogenesisGO:0045766280.013
regulation of saliva secretionGO:004687730.013
cellular response to tumor necrosis factorGO:0071356460.013
organic hydroxy compound transportGO:0015850770.013
neuron neuron synaptic transmissionGO:0007270600.013
inorganic anion transportGO:0015698410.013
response to transition metal nanoparticleGO:19902671220.013
purine ribonucleotide metabolic processGO:00091502270.013
transcription from rna polymerase ii promoterGO:00063662520.013
eye developmentGO:0001654500.013
multicellular organism growthGO:003526410.013
positive regulation of cell proliferationGO:00082842490.013
regulation of kinase activityGO:00435491170.012
cellular response to external stimulusGO:00714961180.012
cytosolic calcium ion homeostasisGO:00514801400.012
neuron projection developmentGO:00311752730.012
cell projection organizationGO:00300303020.012
regulation of locomotionGO:00400121480.012
lipid metabolic processGO:00066292830.012
regulation of transporter activityGO:0032409500.012
cellular response to nutrientGO:0031670300.012
organic substance catabolic processGO:19015753160.012
forebrain developmentGO:0030900980.012
monocarboxylic acid transportGO:0015718520.012
reproductive system developmentGO:00614581280.012
organ inductionGO:000175910.012
response to fatty acidGO:0070542650.012
hindlimb morphogenesisGO:003513720.012
response to extracellular stimulusGO:00099913800.012
keratinocyte differentiationGO:003021620.012
cellular response to steroid hormone stimulusGO:0071383930.012
single organism cellular localizationGO:19025801020.012
regulation of purine nucleotide biosynthetic processGO:1900371460.012
mapk cascadeGO:00001651400.012
cellular lipid metabolic processGO:00442552080.012
spermatogenesisGO:0007283990.012
positive regulation of locomotionGO:00400171020.012
cellular response to oxidative stressGO:0034599760.012
drug transportGO:0015893180.011
nucleotide metabolic processGO:00091172790.011
myeloid leukocyte differentiationGO:0002573200.011
myelinationGO:0042552390.011
negative regulation of catalytic activityGO:00430861030.011
development of primary sexual characteristicsGO:00451371070.011
regulation of homeostatic processGO:00328441010.011
negative regulation of innate immune responseGO:004582440.011
biological adhesionGO:00226101100.011
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.011
wound healingGO:00420601220.011
signal transduction by phosphorylationGO:00230141440.011
regulation of canonical wnt signaling pathwayGO:006082840.011
cell motilityGO:00488702020.011
positive regulation of nucleotide metabolic processGO:0045981910.011
cell projection morphogenesisGO:00488581230.011
single organism organelle organizationGO:19025891800.011
response to gonadotropinGO:0034698340.011
hematopoietic or lymphoid organ developmentGO:0048534360.011
protein homotrimerizationGO:0070207150.011
steroid metabolic processGO:0008202730.011
cellular response to biotic stimulusGO:0071216590.011
regulation of peptide secretionGO:0002791820.011
camera type eye morphogenesisGO:004859320.011
response to molecule of fungal originGO:000223830.011
synaptic transmission gabaergicGO:0051932220.011
male gamete generationGO:0048232990.011
somatic diversification of immune receptors via germline recombination within a single locusGO:000256220.011
regulation of nucleic acid templated transcriptionGO:19035063800.011
neurotransmitter gated ion channel clusteringGO:007257830.011
positive regulation of isotype switchingGO:004583010.011
steroid biosynthetic processGO:0006694480.011
positive regulation of lymphocyte migrationGO:200040310.011
fatty acid metabolic processGO:0006631990.011
skeletal muscle cell differentiationGO:003591420.011
monocarboxylic acid biosynthetic processGO:0072330480.011
limb morphogenesisGO:003510840.011
regulation of organ formationGO:000315620.011
positive regulation of homeostatic processGO:0032846490.011
positive regulation of gene expressionGO:00106282440.011
fatty acid derivative metabolic processGO:1901568380.011
regulation of cell morphogenesisGO:0022604770.011
cellular cation homeostasisGO:00300031800.010
negative regulation of viral processGO:004852540.010
regulation of immunoglobulin secretionGO:005102310.010
regulation of epithelial cell proliferationGO:0050678490.010
organic acid biosynthetic processGO:0016053830.010
androgen biosynthetic processGO:0006702100.010
cellular response to oxygen levelsGO:0071453600.010
b cell mediated immunityGO:001972440.010
male gonad developmentGO:0008584590.010
lung developmentGO:0030324430.010
hormone metabolic processGO:0042445690.010
regulation of skeletal muscle tissue regenerationGO:004341620.010
response to nutrientGO:00075842480.010
cellular response to cytokine stimulusGO:00713451270.010
regulation of transcription from rna polymerase ii promoterGO:00063572340.010
renal system developmentGO:0072001670.010
response to anoxiaGO:003405940.010
response to hexoseGO:00097461440.010

Cubn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.061
nervous system diseaseDOID:86300.061
sensory system diseaseDOID:005015500.033
disease of metabolismDOID:001466700.030
lipid metabolism disorderDOID:314600.020
steroid inherited metabolic disorderDOID:170100.020
inherited metabolic disorderDOID:65500.020
congenital adrenal hyperplasiaDOID:005081100.020
eye diseaseDOID:561400.015
eye and adnexa diseaseDOID:149200.015
central nervous system diseaseDOID:33100.011
urinary system diseaseDOID:1800.011
kidney diseaseDOID:55700.011