Rattus norvegicus

0 known processes

Rasl11a

RAS-like family 11 member A

Rasl11a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell projection organizationGO:00300303020.103
regulation of multicellular organismal developmentGO:20000263760.101
protein phosphorylationGO:00064683450.092
cellular response to oxygen containing compoundGO:19017013860.091
cellular response to endogenous stimulusGO:00714953770.088
neuron differentiationGO:00301823680.084
cellular component movementGO:00069282480.081
neuron projection developmentGO:00311752730.078
cell cell signalingGO:00072673350.075
regulation of cell proliferationGO:00421273590.073
regulation of nucleic acid templated transcriptionGO:19035063800.070
Mouse
secretion by cellGO:00329402480.068
response to extracellular stimulusGO:00099913800.068
neuron developmentGO:00486662860.068
response to nutrient levelsGO:00316673700.066
carboxylic acid metabolic processGO:00197522890.063
cardiovascular system developmentGO:00723581340.063
response to nutrientGO:00075842480.063
cation transportGO:00068123820.063
positive regulation of transportGO:00510502450.062
regulation of cellular localizationGO:00603412630.061
secretionGO:00469033070.060
apoptotic processGO:00069153810.058
single organism reproductive processGO:00447022970.058
cellular response to organic cyclic compoundGO:00714072020.057
regulation of secretion by cellGO:19035302080.057
oxoacid metabolic processGO:00434362900.056
metal ion transportGO:00300012890.055
positive regulation of nitrogen compound metabolic processGO:00511733340.055
Mouse
lipid metabolic processGO:00066292830.055
cellular response to peptideGO:19016531330.055
homeostatic processGO:00425923310.054
regulation of phosphorus metabolic processGO:00511743490.054
cellular amino acid metabolic processGO:00065201070.053
regulation of signal transductionGO:00099663180.052
regulation of cellular protein metabolic processGO:00322682670.052
regulation of neurogenesisGO:00507672470.051
organic acid metabolic processGO:00060822920.051
regulation of phosphate metabolic processGO:00192203490.051
regulation of apoptotic processGO:00429813350.051
regulation of hormone levelsGO:00108171870.051
regulation of protein phosphorylationGO:00019321830.051
cellular response to peptide hormone stimulusGO:00713751200.050
reproductive processGO:00224143720.050
positive regulation of cell communicationGO:00106472710.049
cellular response to lipidGO:00713962010.049
carbohydrate derivative metabolic processGO:19011353460.048
response to glucocorticoidGO:00513842230.048
nitrogen compound transportGO:00717052290.048
regenerationGO:00310991630.048
response to decreased oxygen levelsGO:00362932370.048
positive regulation of phosphorus metabolic processGO:00105622620.048
positive regulation of multicellular organismal processGO:00512403870.048
regulation of protein metabolic processGO:00512462890.047
intracellular signal transductionGO:00355563140.047
negative regulation of multicellular organismal processGO:00512412030.047
response to peptideGO:19016522920.047
anatomical structure morphogenesisGO:00096532980.047
circulatory system processGO:00030131830.046
regulation of programmed cell deathGO:00430673410.046
regulation of cellular component organizationGO:00511283680.045
regulation of protein modification processGO:00313991940.044
regulation of molecular functionGO:00650093980.044
regulation of secretionGO:00510462240.044
positive regulation of signal transductionGO:00099671750.044
transmembrane transportGO:00550854120.043
ion homeostasisGO:00508012120.043
response to oxygen levelsGO:00704822650.043
amine metabolic processGO:0009308380.043
regulation of cell differentiationGO:00455953200.043
protein complex biogenesisGO:00702712630.043
cellular response to organonitrogen compoundGO:00714171970.043
response to woundingGO:00096112540.042
agingGO:00075682410.042
cellular component assemblyGO:00226073600.042
divalent inorganic cation homeostasisGO:00725071650.042
response to hypoxiaGO:00016662310.041
regulation of locomotionGO:00400121480.041
regulation of cellular ketone metabolic processGO:0010565270.041
response to inorganic substanceGO:00100353770.041
macromolecular complex subunit organizationGO:00439333390.041
cell migrationGO:00164771970.041
positive regulation of phosphorylationGO:00423271770.041
programmed cell deathGO:00125013920.040
positive regulation of signalingGO:00230562700.040
cellular amine metabolic processGO:0044106380.040
locomotionGO:00400112370.040
cellular ion homeostasisGO:00068731840.040
cellular divalent inorganic cation homeostasisGO:00725031620.039
localization of cellGO:00516742020.039
chemical homeostasisGO:00488782920.039
cellular calcium ion homeostasisGO:00068741600.039
positive regulation of cell proliferationGO:00082842490.039
positive regulation of neurogenesisGO:00507691650.039
cellular response to stressGO:00335542690.039
regulation of catalytic activityGO:00507903040.039
central nervous system developmentGO:00074173110.038
enzyme linked receptor protein signaling pathwayGO:00071671160.038
regulation of nervous system developmentGO:00519602640.038
negative regulation of metabolic processGO:00098923310.038
response to corticosteroidGO:00319602350.038
cellular ketone metabolic processGO:0042180510.038
regulation of intracellular signal transductionGO:19025312180.038
transcription dna templatedGO:00063513770.038
Mouse
gland developmentGO:00487321550.038
growthGO:00400071650.038
response to growth factorGO:00708481890.038
positive regulation of protein metabolic processGO:00512471780.037
regulation of ion transportGO:00432692450.037
synaptic transmissionGO:00072682350.036
circulatory system developmentGO:00723591340.036
response to metal ionGO:00100382530.036
cellular chemical homeostasisGO:00550822470.036
monovalent inorganic cation transportGO:00156721720.036
response to external biotic stimulusGO:00432072210.036
response to radiationGO:00093141370.035
positive regulation of nucleobase containing compound metabolic processGO:00459353190.035
Mouse
macromolecular complex assemblyGO:00650032730.035
cell motilityGO:00488702020.035
response to bacteriumGO:00096172000.035
positive regulation of cellular biosynthetic processGO:00313282950.035
Mouse
response to peptide hormoneGO:00434342780.035
hormone transportGO:00099141210.035
cellular component biogenesisGO:00440853680.034
blood circulationGO:00080151830.034
g protein coupled receptor signaling pathwayGO:00071862420.034
regulation of phosphorylationGO:00423252480.034
rhythmic processGO:00485111560.034
positive regulation of cellular protein metabolic processGO:00322701670.034
positive regulation of protein phosphorylationGO:00019341350.034
regulation of cellular amine metabolic processGO:003323880.034
regulation of neuron differentiationGO:00456642080.034
cation homeostasisGO:00550801950.033
cellular response to hormone stimulusGO:00328702470.033
regulation of cellular amino acid metabolic processGO:000652120.033
positive regulation of developmental processGO:00510942830.033
regulation of cell developmentGO:00602842630.033
cellular homeostasisGO:00197252520.033
positive regulation of cell differentiationGO:00455972170.033
regulation of transcription dna templatedGO:00063553740.033
Mouse
response to monosaccharideGO:00342841590.033
regulation of cell motilityGO:20001451310.033
positive regulation of response to stimulusGO:00485842850.032
multi organism reproductive processGO:00447032620.032
defense responseGO:00069521940.032
negative regulation of cellular metabolic processGO:00313242810.032
negative regulation of signalingGO:00230571570.032
brain developmentGO:00074202470.032
response to carbohydrateGO:00097431830.032
nucleobase containing small molecule metabolic processGO:00550863160.032
positive regulation of protein modification processGO:00314011420.031
rna biosynthetic processGO:00327743800.031
Mouse
response to estrogenGO:00436272320.031
regulation of system processGO:00440572080.031
vesicle mediated transportGO:00161921810.031
behaviorGO:00076102050.030
nucleotide metabolic processGO:00091172790.030
multicellular organism reproductionGO:00325042330.030
rna metabolic processGO:00160704060.030
Mouse
cellular response to nitrogen compoundGO:19016992100.030
regulation of cell projection organizationGO:00313441750.030
regulation of cellular component movementGO:00512701500.030
nucleoside phosphate metabolic processGO:00067532830.030
regulation of cell migrationGO:00303341280.030
negative regulation of cell deathGO:00605482290.030
regulation of rna metabolic processGO:00512523910.030
Mouse
multicellular organismal reproductive processGO:00486092330.029
organophosphate metabolic processGO:00196373700.029
positive regulation of phosphate metabolic processGO:00459372620.029
response to molecule of bacterial originGO:00022371940.029
negative regulation of cell proliferationGO:00082851190.029
calcium ion homeostasisGO:00550741620.029
negative regulation of response to stimulusGO:00485851550.029
developmental growthGO:00485891000.029
neuron deathGO:00709971270.029
organ regenerationGO:00311001010.028
response to acid chemicalGO:00011012220.028
positive regulation of cell deathGO:00109421840.028
anion transportGO:00068201780.028
hormone secretionGO:00468791150.028
positive regulation of cell developmentGO:00107201760.028
regulation of neuron projection developmentGO:00109751610.028
positive regulation of cellular component organizationGO:00511302000.028
protein complex subunit organizationGO:00718223020.028
head developmentGO:00603222470.028
positive regulation of molecular functionGO:00440932300.028
single organism catabolic processGO:00447122830.028
regulation of membrane potentialGO:00423911100.027
amide transportGO:00428861050.027
ribose phosphate metabolic processGO:00196932350.027
response to ketoneGO:19016541820.027
positive regulation of secretionGO:00510471400.027
positive regulation of cell motilityGO:2000147970.027
positive regulation of biosynthetic processGO:00098913190.027
Mouse
divalent inorganic cation transportGO:00725111340.027
signal releaseGO:00230611450.027
positive regulation of catalytic activityGO:00430851840.027
negative regulation of nitrogen compound metabolic processGO:00511721610.026
peptide secretionGO:0002790860.026
metal ion homeostasisGO:00550651860.026
vasculature developmentGO:0001944700.026
transcription from rna polymerase ii promoterGO:00063662520.026
cellular response to cytokine stimulusGO:00713451270.026
positive regulation of apoptotic processGO:00430651540.026
cellular metal ion homeostasisGO:00068751720.026
macromolecule localizationGO:00330362520.025
response to lipopolysaccharideGO:00324961910.025
catabolic processGO:00090563510.025
regulation of neuron deathGO:19012141150.025
cellular response to growth factor stimulusGO:00713631620.025
nucleic acid templated transcriptionGO:00976593790.025
Mouse
single organism biosynthetic processGO:00447113420.025
neurological system processGO:00508772190.025
response to vitaminGO:00332731310.025
negative regulation of macromolecule metabolic processGO:00106052600.025
response to glucoseGO:00097491360.025
negative regulation of gene expressionGO:00106291990.025
response to oxidative stressGO:00069791860.025
negative regulation of biosynthetic processGO:00098901680.025
negative regulation of apoptotic processGO:00430661810.025
positive regulation of programmed cell deathGO:00430681570.025
positive regulation of cytosolic calcium ion concentrationGO:00072041220.024
reproductive system developmentGO:00614581280.024
anatomical structure formation involved in morphogenesisGO:0048646830.024
organic acid transportGO:00158491160.024
dna metabolic processGO:0006259960.024
cellular lipid metabolic processGO:00442552080.024
calcium ion transportGO:00068161310.024
cytosolic calcium ion homeostasisGO:00514801400.024
cellular response to alcoholGO:0097306870.024
positive regulation of locomotionGO:00400171020.024
peptide transportGO:0015833970.024
positive regulation of nervous system developmentGO:00519621780.024
biological adhesionGO:00226101100.024
negative regulation of cell communicationGO:00106481580.024
developmental process involved in reproductionGO:00030061590.024
cellular response to external stimulusGO:00714961180.024
regulation of hormone secretionGO:00468831060.024
tissue developmentGO:00098882520.024
ion transmembrane transportGO:00342203650.024
response to hydrogen peroxideGO:0042542890.024
protein localizationGO:00081041910.023
organic substance catabolic processGO:19015753160.023
response to organophosphorusGO:00466831020.023
purine containing compound metabolic processGO:00725212530.023
positive regulation of nucleic acid templated transcriptionGO:19035081970.023
Mouse
response to hexoseGO:00097461440.023
insulin secretionGO:0030073690.023
protein oligomerizationGO:00512591910.023
single organism carbohydrate metabolic processGO:00447231180.023
positive regulation of cell projection organizationGO:00313461110.023
organic anion transportGO:00157111320.023
cellular response to steroid hormone stimulusGO:0071383930.023
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.023
organelle organizationGO:00069962660.023
blood vessel morphogenesisGO:0048514580.022
response to campGO:0051591910.022
response to purine containing compoundGO:00140741260.022
response to biotic stimulusGO:00096072260.022
mapk cascadeGO:00001651400.022
cellular catabolic processGO:00442482950.022
carboxylic acid transportGO:00469421150.022
inorganic ion transmembrane transportGO:00986602290.022
regulation of homeostatic processGO:00328441010.022
positive regulation of macromolecule biosynthetic processGO:00105572470.022
Mouse
immune system processGO:00023762040.022
positive regulation of neuron projection developmentGO:0010976990.022
purine ribonucleotide metabolic processGO:00091502270.022
reproductionGO:00000032450.022
negative regulation of macromolecule biosynthetic processGO:00105581480.022
cell part morphogenesisGO:00329901230.021
response to estradiolGO:00323551640.021
positive regulation of intracellular signal transductionGO:19025331380.021
inflammatory responseGO:00069541500.021
regulation of rna biosynthetic processGO:20011413810.021
Mouse
ribonucleoside metabolic processGO:00091191740.021
positive regulation of cellular amino acid metabolic processGO:004576410.021
positive regulation of secretion by cellGO:19035321280.021
positive regulation of cellular amine metabolic processGO:003324030.021
kidney developmentGO:0001822670.021
gastrulationGO:000736920.021
regulation of anatomical structure sizeGO:00900661350.021
ribonucleotide metabolic processGO:00092592310.021
regulation of transcription from rna polymerase ii promoterGO:00063572340.021
divalent metal ion transportGO:00708381320.021
purine nucleotide metabolic processGO:00061632290.021
positive regulation of neuron differentiationGO:00456661260.020
reproductive structure developmentGO:00486081280.020
signal transduction by phosphorylationGO:00230141440.020
cellular cation homeostasisGO:00300031800.020
cellular component morphogenesisGO:00329891550.020
negative regulation of cell differentiationGO:0045596990.020
peptide hormone secretionGO:0030072840.020
protein complex assemblyGO:00064612630.020
cyclic nucleotide metabolic processGO:0009187800.020
neuron apoptotic processGO:0051402880.020
regulation of dna metabolic processGO:0051052600.020
mesoderm developmentGO:000749820.020
establishment of tissue polarityGO:000716420.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.020
negative regulation of developmental processGO:00510931250.019
organonitrogen compound biosynthetic processGO:19015661670.019
cellular nitrogen compound catabolic processGO:00442701630.019
positive regulation of ion transportGO:0043270940.019
regulation of peptide hormone secretionGO:0090276800.019
response to ethanolGO:00454711620.019
organophosphate biosynthetic processGO:00904071430.019
glycosyl compound metabolic processGO:19016571820.019
tube developmentGO:0035295890.019
response to mechanical stimulusGO:00096121340.019
cellular response to glucocorticoid stimulusGO:0071385680.019
regulation of peptide transportGO:0090087870.019
cation transmembrane transportGO:00986552630.019
action potentialGO:0001508540.019
regulation of neuron apoptotic processGO:0043523830.019
single organism intracellular transportGO:19025821660.018
positive regulation of gene expressionGO:00106282440.018
Mouse
negative regulation of cellular biosynthetic processGO:00313271610.018
muscle tissue developmentGO:0060537580.018
gliogenesisGO:0042063930.018
organic cyclic compound catabolic processGO:19013611750.018
ras protein signal transductionGO:0007265290.018
negative regulation of molecular functionGO:00440921330.018
regulation of transferase activityGO:00513381230.018
negative regulation of cellular component organizationGO:0051129830.018
positive regulation of cell migrationGO:0030335960.018
response to hyperoxiaGO:0055093450.018
cell type specific apoptotic processGO:00972851340.018
maintenance of locationGO:0051235170.018
single organism organelle organizationGO:19025891800.017
positive regulation of transcription dna templatedGO:00458931970.017
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.017
female pregnancyGO:00075651220.017
response to other organismGO:00517072200.017
positive regulation of cellular component movementGO:00512721020.017
heterocycle catabolic processGO:00467001670.017
response to reactive oxygen speciesGO:00003021200.017
fatty acid metabolic processGO:0006631990.017
cell morphogenesisGO:00009021420.017
wound healingGO:00420601220.017
striated muscle tissue developmentGO:0014706580.017
small gtpase mediated signal transductionGO:0007264360.017
lipid biosynthetic processGO:00086101280.017
negative regulation of programmed cell deathGO:00430691830.017
vascular process in circulatory systemGO:0003018960.017
regulation of anatomical structure morphogenesisGO:00226031410.016
negative regulation of neurogenesisGO:0050768780.016
cell growthGO:00160491040.016
response to alkaloidGO:00432791320.016
negative regulation of nervous system developmentGO:0051961790.016
response to cytokineGO:00340972150.016
development of primary sexual characteristicsGO:00451371070.016
inorganic cation transmembrane transportGO:00986622020.016
intracellular transportGO:00469071850.016
cellular response to insulin stimulusGO:0032869810.016
endocytosisGO:0006897840.016
regulation of growthGO:00400081050.016
nucleoside phosphate biosynthetic processGO:19012931020.016
peptidyl amino acid modificationGO:00181931260.016
neuronal action potentialGO:0019228350.016
cell adhesionGO:00071551100.016
heart morphogenesisGO:000300730.016
axis specificationGO:000979840.015
regulation of synaptic transmissionGO:00508041410.015
organonitrogen compound catabolic processGO:19015651790.015
liver developmentGO:0001889900.015
negative regulation of nucleobase containing compound metabolic processGO:00459341530.015
regulation of kinase activityGO:00435491170.015
sequestering of calcium ionGO:005120880.015
regulation of blood circulationGO:19035221100.015
regulation of protein kinase activityGO:00458591050.015
regulation of ion transmembrane transportGO:00347651210.015
axon developmentGO:0061564960.015
anterior posterior pattern specificationGO:000995210.015
negative regulation of neuron differentiationGO:0045665620.015
cell fate determinationGO:000170920.015
monocarboxylic acid metabolic processGO:00327871520.015
positive regulation of blood circulationGO:1903524650.015
cell projection morphogenesisGO:00488581230.015
cytokine mediated signaling pathwayGO:0019221430.015
regulation of metal ion transportGO:00109591180.015
membrane organizationGO:0061024940.015
epithelium developmentGO:0060429960.015
regulation of response to external stimulusGO:00321011060.015
regulation of mapk cascadeGO:00434081160.015
regulation of immune system processGO:00026821230.015
chromosome segregationGO:000705920.015
regulation of tube sizeGO:0035150890.015
nucleoside metabolic processGO:00091161790.014
response to increased oxygen levelsGO:0036296450.014
organ morphogenesisGO:0009887750.014
heart developmentGO:0007507720.014
nucleobase containing compound catabolic processGO:00346551520.014
negative regulation of rna metabolic processGO:00512531230.014
peptidyl tyrosine phosphorylationGO:0018108720.014
ribose phosphate biosynthetic processGO:0046390870.014
meiotic cell cycle processGO:190304630.014
nucleotide biosynthetic processGO:0009165980.014
actin filament based processGO:0030029860.014
negative regulation of protein metabolic processGO:00512481140.014
cellular response to drugGO:0035690300.014
sexual reproductionGO:00199531480.014
ribonucleotide catabolic processGO:00092611360.014
monosaccharide metabolic processGO:0005996610.014
nucleoside phosphate catabolic processGO:19012921400.014
nucleotide catabolic processGO:00091661390.014
neuron projection morphogenesisGO:00488121220.014
positive regulation of immune system processGO:0002684900.014
proteolysisGO:00065081750.014
halogenated hydrocarbon metabolic processGO:004219740.014
response to cadmium ionGO:0046686350.014
bmp signaling pathwayGO:003050940.014
response to amino acidGO:0043200750.014
angiogenesisGO:0001525530.014
cellular response to extracellular stimulusGO:0031668730.014
single organism cellular localizationGO:19025801020.014
purine containing compound biosynthetic processGO:0072522850.014
salivary gland developmentGO:000743130.014
multi multicellular organism processGO:00447061380.014
response to transition metal nanoparticleGO:19902671220.014
gamete generationGO:00072761240.013
carbohydrate derivative biosynthetic processGO:19011371240.013
positive regulation of rna metabolic processGO:00512542030.013
Mouse
alpha amino acid metabolic processGO:1901605710.013
positive regulation of kinase activityGO:0033674770.013
positive regulation of rna biosynthetic processGO:19026801970.013
Mouse
organic hydroxy compound metabolic processGO:19016151150.013
reactive oxygen species metabolic processGO:0072593370.013
positive regulation of transferase activityGO:0051347810.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
response to low density lipoprotein particleGO:005509840.013
immune responseGO:00069551040.013
carbohydrate derivative catabolic processGO:19011361470.013
aromatic compound catabolic processGO:00194391680.013
regulation of blood vessel sizeGO:0050880890.013
exocytosisGO:0006887600.013
regulation of insulin secretionGO:0050796650.013
carbohydrate metabolic processGO:00059751300.013
carbohydrate homeostasisGO:0033500750.013
negative regulation of cell developmentGO:0010721820.013
blood vessel developmentGO:0001568690.013
cytoplasmic transportGO:00164821150.013
purine ribonucleoside metabolic processGO:00461281680.013
response to toxic substanceGO:00096361330.013
negative regulation of phosphate metabolic processGO:0045936800.013
purine ribonucleotide biosynthetic processGO:0009152810.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
regulation of organelle organizationGO:0033043800.013
regulation of response to stressGO:00801341260.013
lipid storageGO:001991510.013
regulation of calcium ion transportGO:0051924770.013
response to tumor necrosis factorGO:0034612560.013
negative regulation of signal transductionGO:0009968830.013
reactive oxygen species biosynthetic processGO:190340980.013
negative regulation of nucleic acid templated transcriptionGO:19035071170.013
striated muscle contractionGO:0006941440.013
small molecule biosynthetic processGO:00442831240.013
sensory perceptionGO:00076001010.013
response to light stimulusGO:0009416520.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.012
female gonad developmentGO:0008585530.012
amino acid transportGO:0006865700.012
response to ionizing radiationGO:0010212590.012
embryonic pattern specificationGO:000988010.012
regulation of transmembrane transportGO:00347621220.012
negative regulation of rna biosynthetic processGO:19026791180.012
response to retinoic acidGO:0032526630.012
hepaticobiliary system developmentGO:0061008900.012
peptidyl tyrosine modificationGO:0018212720.012
cellular modified amino acid metabolic processGO:0006575610.012
muscle cell proliferationGO:0033002840.012
purine nucleoside metabolic processGO:00422781690.012
response to electrical stimulusGO:0051602560.012
negative regulation of innate immune responseGO:004582440.012
cellular response to oxidative stressGO:0034599760.012
multicellular organism growthGO:003526410.012
female sex differentiationGO:0046660590.012
monocarboxylic acid transportGO:0015718520.012
urogenital system developmentGO:0001655780.012
protein heterooligomerizationGO:0051291890.012
purine ribonucleoside catabolic processGO:00461301240.012
regulation of smooth muscle cell proliferationGO:0048660750.012
sex differentiationGO:00075481130.012
sequestering of metal ionGO:005123890.012
cellular response to abiotic stimulusGO:0071214850.012
positive regulation of homeostatic processGO:0032846490.012
purine nucleoside triphosphate catabolic processGO:00091461220.012
ovulation cycle processGO:0022602500.012

Rasl11a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.024
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
musculoskeletal system diseaseDOID:1700.017
sensory system diseaseDOID:005015500.014
cardiovascular system diseaseDOID:128700.014
central nervous system diseaseDOID:33100.013
gastrointestinal system diseaseDOID:7700.013