Rattus norvegicus

0 known processes

Serpina4

serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4

(Aliases: MGC108582)

Serpina4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to lipidGO:00713962010.730
Rat
response to extracellular stimulusGO:00099913800.566
Rat
cellular response to glucocorticoid stimulusGO:0071385680.356
Rat
response to other organismGO:00517072200.352
Rat
cellular response to steroid hormone stimulusGO:0071383930.342
Rat
cellular amino acid metabolic processGO:00065201070.339
cellular response to hormone stimulusGO:00328702470.270
Rat
response to vitaminGO:00332731310.263
Rat
response to biotic stimulusGO:00096072260.256
Rat
cellular response to organic cyclic compoundGO:00714072020.256
Rat
response to nutrient levelsGO:00316673700.249
Rat
cell motilityGO:00488702020.249
alpha amino acid metabolic processGO:1901605710.246
response to cytokineGO:00340972150.217
Rat
response to glucocorticoidGO:00513842230.212
Rat
cellular response to oxygen containing compoundGO:19017013860.203
Rat
response to mechanical stimulusGO:00096121340.201
Rat
response to peptideGO:19016522920.189
Rat
response to nutrientGO:00075842480.188
Rat
response to purine containing compoundGO:00140741260.183
Rat
cell migrationGO:00164771970.179
regulation of locomotionGO:00400121480.172
cellular response to alcoholGO:0097306870.165
homeostatic processGO:00425923310.165
Rat
cellular response to nitrogen compoundGO:19016992100.162
Rat
oxoacid metabolic processGO:00434362900.158
regulation of cell motilityGO:20001451310.158
multi multicellular organism processGO:00447061380.156
Rat
response to triglycerideGO:003401430.149
Rat
rhythmic processGO:00485111560.149
localization of cellGO:00516742020.145
response to campGO:0051591910.143
Rat
cation transportGO:00068123820.138
Rat
organic acid metabolic processGO:00060822920.136
cellular response to corticosteroid stimulusGO:0071384690.132
Rat
regulation of cellular component movementGO:00512701500.132
carboxylic acid metabolic processGO:00197522890.130
response to external biotic stimulusGO:00432072210.125
Rat
single organism nuclear importGO:1902593350.117
Rat
response to lipopolysaccharideGO:00324961910.112
Rat
cellular response to external stimulusGO:00714961180.110
Rat
response to corticosteroidGO:00319602350.108
Rat
response to woundingGO:00096112540.107
locomotionGO:00400112370.107
purine nucleoside monophosphate metabolic processGO:0009126840.103
unsaturated fatty acid metabolic processGO:0033559390.102
response to organophosphorusGO:00466831020.102
Rat
positive regulation of cellular component movementGO:00512721020.095
negative regulation of cell deathGO:00605482290.094
positive regulation of immune system processGO:0002684900.093
nitrogen compound transportGO:00717052290.090
Rat
cellular response to peptide hormone stimulusGO:00713751200.090
cell growthGO:00160491040.087
Rat
sulfur compound metabolic processGO:0006790700.085
regulation of cell migrationGO:00303341280.084
programmed cell deathGO:00125013920.083
Rat
apoptotic processGO:00069153810.083
Rat
positive regulation of locomotionGO:00400171020.081
regulation of metal ion transportGO:00109591180.080
Rat
regulation of apoptotic processGO:00429813350.078
Rat
cellular lipid metabolic processGO:00442552080.077
organic acid transportGO:00158491160.076
regulation of multicellular organismal developmentGO:20000263760.075
Rat
regulation of serine type peptidase activityGO:190257110.074
Rat
kidney developmentGO:0001822670.073
response to inorganic substanceGO:00100353770.073
Rat
negative regulation of gene expressionGO:00106291990.071
Rat
response to hexoseGO:00097461440.070
carboxylic acid biosynthetic processGO:0046394830.070
inflammatory responseGO:00069541500.070
Rat
regulation of secretion by cellGO:19035302080.069
Rat
response to estradiolGO:00323551640.069
Rat
cellular response to insulin stimulusGO:0032869810.068
regulation of cell growthGO:0001558850.068
Rat
negative regulation of macromolecule metabolic processGO:00106052600.067
Rat
immune system processGO:00023762040.066
Rat
circadian rhythmGO:0007623880.065
regulation of programmed cell deathGO:00430673410.065
Rat
gland developmentGO:00487321550.061
response to ethanolGO:00454711620.061
response to estrogenGO:00436272320.061
Rat
protein phosphorylationGO:00064683450.061
secretionGO:00469033070.060
Rat
reproductionGO:00000032450.059
intracellular signal transductionGO:00355563140.059
Rat
positive regulation of gene expressionGO:00106282440.058
anion transportGO:00068201780.058
nuclear importGO:0051170350.057
Rat
multi organism reproductive processGO:00447032620.057
Rat
cellular response to endogenous stimulusGO:00714953770.056
Rat
lipid transportGO:0006869610.056
negative regulation of apoptotic processGO:00430661810.055
response to glucoseGO:00097491360.055
metal ion transportGO:00300012890.054
Rat
response to activityGO:0014823730.054
Rat
response to acid chemicalGO:00011012220.054
Rat
negative regulation of metabolic processGO:00098923310.054
Rat
peptide transportGO:0015833970.051
regulation of molecular functionGO:00650093980.050
Rat
extracellular matrix constituent secretionGO:007027840.050
Rat
proteolysisGO:00065081750.049
Rat
protein targeting to nucleusGO:0044744350.048
Rat
regulation of cellular amine metabolic processGO:003323880.048
negative regulation of cell proliferationGO:00082851190.048
Rat
tissue developmentGO:00098882520.048
Rat
response to carbohydrateGO:00097431830.048
calcium mediated signalingGO:0019722230.048
negative regulation of cellular metabolic processGO:00313242810.048
Rat
regulation of cell differentiationGO:00455953200.047
regulation of phosphorylationGO:00423252480.047
cellular component movementGO:00069282480.046
negative regulation of response to stimulusGO:00485851550.046
cellular component biogenesisGO:00440853680.046
cellular component assemblyGO:00226073600.046
acid secretionGO:0046717480.045
response to oxygen levelsGO:00704822650.044
Rat
response to transition metal nanoparticleGO:19902671220.044
Rat
growthGO:00400071650.044
Rat
amine metabolic processGO:0009308380.044
negative regulation of developmental processGO:00510931250.043
Rat
regulation of transcription dna templatedGO:00063553740.043
single organism intracellular transportGO:19025821660.043
Rat
reproductive processGO:00224143720.042
Rat
organophosphate metabolic processGO:00196373700.042
regulation of rna biosynthetic processGO:20011413810.042
response to metal ionGO:00100382530.042
Rat
central nervous system developmentGO:00074173110.042
glycoside transportGO:190165620.042
regulation of cellular ketone metabolic processGO:0010565270.041
cellular response to stressGO:00335542690.041
Rat
immune system developmentGO:0002520410.041
organic substance catabolic processGO:19015753160.041
response to molecule of bacterial originGO:00022371940.041
Rat
organic acid biosynthetic processGO:0016053830.041
secretion by cellGO:00329402480.041
Rat
regulation of hydrolase activityGO:00513361430.040
Rat
positive regulation of macromolecule biosynthetic processGO:00105572470.040
response to bacteriumGO:00096172000.040
Rat
cellular ion homeostasisGO:00068731840.040
Rat
cellular response to organonitrogen compoundGO:00714171970.040
Rat
lipid localizationGO:0010876620.040
regulation of cellular component organizationGO:00511283680.039
Rat
regulation of immune system processGO:00026821230.039
negative regulation of programmed cell deathGO:00430691830.039
positive regulation of developmental processGO:00510942830.038
regulation of ion transportGO:00432692450.038
Rat
cellular metal ion homeostasisGO:00068751720.037
Rat
negative regulation of molecular functionGO:00440921330.037
Rat
carbohydrate derivative metabolic processGO:19011353460.037
positive regulation of secretionGO:00510471400.037
Rat
insulin like growth factor receptor signaling pathwayGO:004800930.037
rna biosynthetic processGO:00327743800.036
response to mineralocorticoidGO:0051385490.036
Rat
response to amino acidGO:0043200750.035
positive regulation of transportGO:00510502450.035
Rat
positive regulation of extracellular matrix constituent secretionGO:000333120.035
Rat
positive regulation of cell proliferationGO:00082842490.035
Rat
negative regulation of endopeptidase activityGO:0010951360.034
Rat
endocytosisGO:0006897840.034
rna metabolic processGO:00160704060.034
renal system developmentGO:0072001670.034
regulation of cellular localizationGO:00603412630.033
Rat
developmental process involved in reproductionGO:00030061590.033
steroid metabolic processGO:0008202730.033
macromolecular complex assemblyGO:00650032730.033
anatomical structure morphogenesisGO:00096532980.033
Rat
immune responseGO:00069551040.033
Rat
g protein coupled receptor signaling pathwayGO:00071862420.033
Rat
negative regulation of multicellular organismal processGO:00512412030.032
Rat
response to insulinGO:00328681330.032
regulation of anatomical structure sizeGO:00900661350.032
Rat
regulation of cell projection organizationGO:00313441750.032
cellular homeostasisGO:00197252520.032
Rat
negative regulation of protein maturationGO:1903318470.032
Rat
response to monosaccharideGO:00342841590.032
regulation of cellular amino acid metabolic processGO:000652120.032
positive regulation of multicellular organismal processGO:00512403870.031
Rat
protein complex biogenesisGO:00702712630.031
negative regulation of peptidase activityGO:0010466380.031
Rat
transmembrane transportGO:00550854120.031
protein complex assemblyGO:00064612630.031
response to peptide hormoneGO:00434342780.030
Rat
response to interleukin 1GO:0070555550.030
Rat
transcription dna templatedGO:00063513770.030
positive regulation of biosynthetic processGO:00098913190.030
Rat
regulation of body fluid levelsGO:0050878900.030
positive regulation of secretion by cellGO:19035321280.029
Rat
positive regulation of cellular component organizationGO:00511302000.029
Rat
single organism biosynthetic processGO:00447113420.029
regulation of response to woundingGO:1903034690.029
regulation of calcium ion transportGO:0051924770.029
Rat
cellular amine metabolic processGO:0044106380.029
cellular carbohydrate metabolic processGO:0044262720.029
agingGO:00075682410.029
Rat
carboxylic acid transportGO:00469421150.028
intracellular transportGO:00469071850.028
Rat
regulation of immune responseGO:0050776550.028
protein complex subunit organizationGO:00718223020.028
negative regulation of protein metabolic processGO:00512481140.028
Rat
protein processingGO:0016485680.028
Rat
nucleic acid templated transcriptionGO:00976593790.028
negative regulation of catalytic activityGO:00430861030.028
Rat
response to ketoneGO:19016541820.027
Rat
divalent inorganic cation transportGO:00725111340.027
Rat
amide transportGO:00428861050.027
positive regulation of nitrogen compound metabolic processGO:00511733340.027
Rat
multicellular organism reproductionGO:00325042330.027
single organism reproductive processGO:00447022970.027
regulation of homeostatic processGO:00328441010.027
Rat
reactive oxygen species biosynthetic processGO:190340980.027
monocarboxylic acid metabolic processGO:00327871520.027
developmental growthGO:00485891000.026
Rat
regulation of nucleic acid templated transcriptionGO:19035063800.026
fatty acid metabolic processGO:0006631990.026
response to hyperoxiaGO:0055093450.026
regulation of anatomical structure morphogenesisGO:00226031410.026
Rat
cellular response to abiotic stimulusGO:0071214850.026
Rat
wound healingGO:00420601220.026
positive regulation of rna biosynthetic processGO:19026801970.026
cellular response to campGO:0071320260.026
Rat
negative regulation of serine type peptidase activityGO:190257210.026
Rat
defense responseGO:00069521940.025
Rat
lipid biosynthetic processGO:00086101280.025
regulation of phosphate metabolic processGO:00192203490.025
circulatory system processGO:00030131830.025
Rat
positive regulation of neurogenesisGO:00507691650.025
cellular sodium ion homeostasisGO:000688340.025
Rat
macromolecule localizationGO:00330362520.025
Rat
regulation of extracellular matrix constituent secretionGO:000333020.025
Rat
amino acid transportGO:0006865700.025
ossificationGO:0001503700.025
regulation of reactive oxygen species biosynthetic processGO:190342650.025
regulation of neuron differentiationGO:00456642080.025
renal sodium excretionGO:0035812200.025
Rat
regulation of protein processingGO:0070613500.025
Rat
positive regulation of cell differentiationGO:00455972170.025
vesicle mediated transportGO:00161921810.024
nucleocytoplasmic transportGO:0006913480.024
Rat
regulation of reactive oxygen species metabolic processGO:2000377260.024
Rat
innate immune responseGO:0045087350.024
Rat
positive regulation of cell motilityGO:2000147970.024
response to vitamin dGO:0033280340.024
macromolecular complex subunit organizationGO:00439333390.024
signal transduction by phosphorylationGO:00230141440.024
Rat
regulation of phosphorus metabolic processGO:00511743490.024
ribose phosphate metabolic processGO:00196932350.024
regulation of endocytosisGO:0030100420.023
regulation of nervous system developmentGO:00519602640.023
signal releaseGO:00230611450.023
divalent metal ion transportGO:00708381320.023
Rat
cellular response to acid chemicalGO:0071229750.023
cellular response to ketoneGO:1901655510.023
negative regulation of serine type endopeptidase activityGO:190000410.023
Rat
tissue remodelingGO:0048771400.023
Rat
regenerationGO:00310991630.023
purine ribonucleoside monophosphate metabolic processGO:0009167840.023
protein maturationGO:0051604680.023
Rat
cellular response to mechanical stimulusGO:0071260480.023
Rat
regulation of neurogenesisGO:00507672470.022
ion transmembrane transportGO:00342203650.022
regulation of protein maturationGO:1903317500.022
Rat
regulation of catalytic activityGO:00507903040.022
Rat
response to decreased oxygen levelsGO:00362932370.022
Rat
organic anion transportGO:00157111320.022
neuron deathGO:00709971270.022
regulation of system processGO:00440572080.021
Rat
transmission of nerve impulseGO:0019226420.021
Rat
positive regulation of cellular amino acid metabolic processGO:004576410.021
regulation of secretionGO:00510462240.021
Rat
regulation of neuron projection developmentGO:00109751610.021
organic cyclic compound catabolic processGO:19013611750.021
blood circulationGO:00080151830.021
Rat
icosanoid metabolic processGO:0006690380.021
vasculature developmentGO:0001944700.020
Rat
reproductive system developmentGO:00614581280.020
protein importGO:0017038370.020
Rat
positive regulation of nervous system developmentGO:00519621780.020
insecticide metabolic processGO:001714340.020
cytoplasmic transportGO:00164821150.020
Rat
cellular modified amino acid metabolic processGO:0006575610.020
cellular ketone metabolic processGO:0042180510.020
positive regulation of cell deathGO:00109421840.020
Rat
nuclear transportGO:0051169490.020
Rat
response to zinc ionGO:0010043390.019
coenzyme metabolic processGO:0006732860.019
monocarboxylic acid transportGO:0015718520.019
positive regulation of programmed cell deathGO:00430681570.019
Rat
nucleobase containing small molecule metabolic processGO:00550863160.019
protein localization to nucleusGO:0034504390.019
Rat
cellular catabolic processGO:00442482950.019
catabolic processGO:00090563510.019
small molecule biosynthetic processGO:00442831240.019
regulation of cellular protein metabolic processGO:00322682670.019
Rat
response to vitamin aGO:0033189360.019
Rat
cellular response to dexamethasone stimulusGO:0071549360.019
ribonucleoside monophosphate metabolic processGO:0009161880.019
regulation of transferase activityGO:00513381230.019
cofactor metabolic processGO:0051186950.019
response to corticosteroneGO:0051412400.019
Rat
lipid metabolic processGO:00066292830.019
regulation of protein kinase activityGO:00458591050.019
regulation of response to stressGO:00801341260.019
cellular cation homeostasisGO:00300031800.019
Rat
angiogenesisGO:0001525530.019
Rat
response to hypoxiaGO:00016662310.018
Rat
urogenital system developmentGO:0001655780.018
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.018
brain renin angiotensin systemGO:000203530.018
Rat
reproductive structure developmentGO:00486081280.018
reactive nitrogen species metabolic processGO:200105710.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.018
nucleoside monophosphate catabolic processGO:0009125560.018
positive regulation of reactive oxygen species biosynthetic processGO:190342820.018
response to foodGO:0032094270.017
gamete generationGO:00072761240.017
negative regulation of cell differentiationGO:0045596990.017
cell projection organizationGO:00300303020.017
response to dexamethasoneGO:0071548490.017
hormone transportGO:00099141210.017
response to chromateGO:004668730.017
Rat
positive regulation of transcription dna templatedGO:00458931970.017
response to starvationGO:0042594590.017
acute inflammatory responseGO:0002526580.017
muscle system processGO:00030121150.017
Rat
negative regulation of nitrogen compound metabolic processGO:00511721610.017
positive regulation of homeostatic processGO:0032846490.017
Rat
atp metabolic processGO:0046034720.016
cognitionGO:0050890920.016
positive regulation of neuron differentiationGO:00456661260.016
renin angiotensin regulation of aldosterone productionGO:000201830.016
Rat
purine nucleoside monophosphate catabolic processGO:0009128550.016
response to radiationGO:00093141370.016
dicarboxylic acid transportGO:0006835340.016
negative regulation of signal transductionGO:0009968830.016
maintenance of locationGO:0051235170.016
brain developmentGO:00074202470.016
organ regenerationGO:00311001010.016
ion homeostasisGO:00508012120.016
Rat
regulation of cell proliferationGO:00421273590.016
Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353190.016
cellular response to cytokine stimulusGO:00713451270.015
Rat
multicellular organismal reproductive processGO:00486092330.015
second messenger mediated signalingGO:0019932510.015
cellular response to extracellular stimulusGO:0031668730.015
embryo developmentGO:0009790490.015
regulation of proteolysisGO:0030162660.015
Rat
response to increased oxygen levelsGO:0036296450.015
chemical homeostasisGO:00488782920.015
Rat
regulation of neuronal synaptic plasticityGO:0048168310.015
Rat
regulation of hormone levelsGO:00108171870.015
tonic smooth muscle contractionGO:001482040.015
Rat
cellular response to peptideGO:19016531330.015
positive regulation of rna metabolic processGO:00512542030.015
cell type specific apoptotic processGO:00972851340.015
chlorinated hydrocarbon metabolic processGO:004219640.015
protein transportGO:00150311320.015
Rat
negative regulation of proteolysisGO:0045861410.015
Rat
transcription from rna polymerase ii promoterGO:00063662520.015
regulation of blood pressureGO:0008217830.015
Rat
protein import into nucleusGO:0006606350.015
Rat
cellular response to nutrient levelsGO:0031669600.014
regulation of peptidase activityGO:0052547550.014
Rat
intracellular protein transportGO:0006886790.014
Rat
positive regulation of cell projection organizationGO:00313461110.014
response to retinoic acidGO:0032526630.014
regulation of cell cycleGO:0051726730.014
response to interleukin 6GO:0070741130.014
Rat
positive regulation of cellular amine metabolic processGO:003324030.014
response to toxic substanceGO:00096361330.014
gonad developmentGO:00084061040.014
fatty acid biosynthetic processGO:0006633330.014
negative regulation of protein processingGO:0010955470.014
Rat
positive regulation of phosphate metabolic processGO:00459372620.013
defense response to gram negative bacteriumGO:005082930.013
spermatogenesisGO:0007283990.013
negative regulation of neuron deathGO:1901215690.013
regulation of membrane potentialGO:00423911100.013
organelle organizationGO:00069962660.013
regulation of transcription from rna polymerase ii promoterGO:00063572340.013
alpha amino acid catabolic processGO:1901606200.013
monocarboxylic acid biosynthetic processGO:0072330480.013
cellular nitrogen compound catabolic processGO:00442701630.013
aromatic amino acid family metabolic processGO:000907290.013
nucleoside monophosphate metabolic processGO:0009123930.013
negative regulation of hydrolase activityGO:0051346520.013
Rat
heterocycle catabolic processGO:00467001670.013
nucleotide metabolic processGO:00091172790.013
peristalsisGO:003043220.013
negative regulation of epithelial cell proliferationGO:0050680160.013
Rat
organonitrogen compound catabolic processGO:19015651790.013
regulation of angiogenesisGO:0045765390.012
Rat
single organism catabolic processGO:00447122830.012
cell activationGO:0001775970.012
ribonucleoside monophosphate catabolic processGO:0009158550.012
regulation of cell developmentGO:00602842630.012
phasic smooth muscle contractionGO:001482130.012
hexose metabolic processGO:0019318580.012
regulation of endopeptidase activityGO:0052548510.012
Rat
multicellular organismal water homeostasisGO:005089140.012
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.012
single organism behaviorGO:00447081300.012
mapk cascadeGO:00001651400.012
Rat
regulation of growthGO:00400081050.012
Rat
sequestering of metal ionGO:005123890.012
response to mercury ionGO:0046689150.012
response to alkaloidGO:00432791320.012
cytokine secretionGO:0050663150.012
Rat
response to lithium ionGO:0010226280.012
cellular response to inorganic substanceGO:0071241650.011
complement activationGO:0006956110.011
regulation of anion transportGO:0044070430.011
regulation of fat cell differentiationGO:004559830.011
steroid biosynthetic processGO:0006694480.011
regulation of signal transductionGO:00099663180.011
cartilage condensationGO:000150220.011
olfactory behaviorGO:004204820.011
cellular protein localizationGO:00346131220.011
Rat
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
Rat
regulation of protein metabolic processGO:00512462890.011
Rat
regulation of vesicle mediated transportGO:0060627810.011
negative regulation of cellular protein metabolic processGO:00322691060.011
Rat
regulation of protein phosphorylationGO:00019321830.011
single organism cellular localizationGO:19025801020.011
Rat
embryo implantationGO:0007566150.011
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.011
Rat
positive regulation of cell developmentGO:00107201760.011
phospholipid metabolic processGO:0006644610.011
cellular amino acid biosynthetic processGO:0008652320.011
protein targetingGO:0006605610.011
Rat
positive regulation of response to stimulusGO:00485842850.011
cellular response to drugGO:0035690300.011
positive regulation of peptide hormone secretionGO:0090277500.011
neurological system processGO:00508772190.011
Rat
positive regulation of fibroblast proliferationGO:0048146150.011
Rat
hindbrain morphogenesisGO:002157520.011
behaviorGO:00076102050.011
Rat
positive regulation of phosphorus metabolic processGO:00105622620.011
circulatory system developmentGO:00723591340.011
Rat
cholesterol homeostasisGO:004263230.010
positive regulation of immune responseGO:0050778420.010
insulin receptor signaling pathwayGO:0008286240.010
regulation of organ formationGO:000315620.010
regulation of neuron deathGO:19012141150.010
protein oligomerizationGO:00512591910.010
cellular chemical homeostasisGO:00550822470.010
Rat
negative regulation of cellular carbohydrate metabolic processGO:001067770.010
hormone secretionGO:00468791150.010
negative regulation of phosphate metabolic processGO:0045936800.010
male gamete generationGO:0048232990.010
regulation of intracellular signal transductionGO:19025312180.010

Serpina4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
vascular diseaseDOID:17800.033
cardiovascular system diseaseDOID:128700.033
disease of metabolismDOID:001466700.016
nervous system diseaseDOID:86300.015
inherited metabolic disorderDOID:65500.015
artery diseaseDOID:005082800.014