IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Creb3

cAMP responsive element binding protein 3

Entrez: 298400
Ensembl: ENSRNOG00000016452
RGD: 1308831
UniProtKB: Q6P6G3

Process Predictions
Disease Predictions

Creb3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
carboxylic acid metabolic process	GO:0019752	289	0.108
organophosphate metabolic process	GO:0019637	370	0.094
organic acid metabolic process	GO:0006082	292	0.090
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.088
nucleoside phosphate metabolic process	GO:0006753	283	0.086
brain development	GO:0007420	247	0.083
cellular catabolic process	GO:0044248	295	0.083
oxoacid metabolic process	GO:0043436	290	0.068
purine nucleoside monophosphate catabolic process	GO:0009128	55	0.063
ribonucleotide catabolic process	GO:0009261	136	0.062
positive regulation of cellular biosynthetic process	GO:0031328	295	0.057	Human
purine nucleoside catabolic process	GO:0006152	124	0.056
programmed cell death	GO:0012501	392	0.055
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.055
single organism catabolic process	GO:0044712	283	0.055
aging	GO:0007568	241	0.055
central nervous system development	GO:0007417	311	0.053
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.051	Human
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.049	Human
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.049
regulation of protein localization	GO:0032880	81	0.048	Human
regulation of programmed cell death	GO:0043067	341	0.048
catabolic process	GO:0009056	351	0.047
purine ribonucleotide catabolic process	GO:0009154	136	0.047
purine nucleotide metabolic process	GO:0006163	229	0.046
regulation of transcription dna templated	GO:0006355	374	0.046	Human
macromolecule localization	GO:0033036	252	0.045	Human
purine nucleotide catabolic process	GO:0006195	136	0.045
purine containing compound metabolic process	GO:0072521	253	0.045
atp catabolic process	GO:0006200	54	0.044
regulation of hydrolase activity	GO:0051336	143	0.043	Human
nucleotide metabolic process	GO:0009117	279	0.043
nucleoside triphosphate catabolic process	GO:0009143	123	0.042
positive regulation of phosphate metabolic process	GO:0045937	262	0.042
proteolysis	GO:0006508	175	0.041
cellular response to stress	GO:0033554	269	0.041	Human
regulation of catabolic process	GO:0009894	113	0.041
negative regulation of macromolecule metabolic process	GO:0010605	260	0.041
cellular protein localization	GO:0034613	122	0.040	Human
nucleoside triphosphate metabolic process	GO:0009141	144	0.040
transcription dna templated	GO:0006351	377	0.038	Human
regulation of rna biosynthetic process	GO:2001141	381	0.037	Human
apoptotic process	GO:0006915	381	0.036
regulation of molecular function	GO:0065009	398	0.036	Human
response to inorganic substance	GO:0010035	377	0.035
purine containing compound catabolic process	GO:0072523	138	0.035
regulation of apoptotic process	GO:0042981	335	0.035
secretion	GO:0046903	307	0.035
ribonucleoside monophosphate metabolic process	GO:0009161	88	0.035
positive regulation of biosynthetic process	GO:0009891	319	0.034	Human
single organism membrane organization	GO:0044802	74	0.034
response to extracellular stimulus	GO:0009991	380	0.034
single organism intracellular transport	GO:1902582	166	0.034	Human
nucleobase containing small molecule metabolic process	GO:0055086	316	0.034
cellular amino acid metabolic process	GO:0006520	107	0.034
purine ribonucleotide metabolic process	GO:0009150	227	0.034
positive regulation of gene expression	GO:0010628	244	0.033	Human
negative regulation of cellular metabolic process	GO:0031324	281	0.033
carbohydrate derivative metabolic process	GO:1901135	346	0.033
ribonucleoside metabolic process	GO:0009119	174	0.033
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.032
intracellular transport	GO:0046907	185	0.032	Human
establishment of protein localization	GO:0045184	141	0.031	Human
response to peptide	GO:1901652	292	0.031
organophosphate catabolic process	GO:0046434	148	0.031
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.031
aromatic compound catabolic process	GO:0019439	168	0.030
protein transport	GO:0015031	132	0.030	Human
membrane organization	GO:0061024	94	0.029
purine nucleoside metabolic process	GO:0042278	169	0.029
carbohydrate derivative catabolic process	GO:1901136	147	0.029
atp metabolic process	GO:0046034	72	0.029
regulation of catalytic activity	GO:0050790	304	0.028	Human
rna metabolic process	GO:0016070	406	0.028	Human
ribose phosphate metabolic process	GO:0019693	235	0.028
regulation of anatomical structure morphogenesis	GO:0022603	141	0.027
regulation of nucleic acid templated transcription	GO:1903506	380	0.027	Human
organic substance catabolic process	GO:1901575	316	0.027
cytoplasmic transport	GO:0016482	115	0.027	Human
reproduction	GO:0000003	245	0.027
regulation of rna metabolic process	GO:0051252	391	0.027	Human
glycosyl compound metabolic process	GO:1901657	182	0.027
positive regulation of catalytic activity	GO:0043085	184	0.026	Human
ribonucleotide metabolic process	GO:0009259	231	0.026
organonitrogen compound catabolic process	GO:1901565	179	0.026
secretion by cell	GO:0032940	248	0.025
head development	GO:0060322	247	0.025
rna biosynthetic process	GO:0032774	380	0.025	Human
organic cyclic compound catabolic process	GO:1901361	175	0.025
single organism biosynthetic process	GO:0044711	342	0.025
reproductive process	GO:0022414	372	0.025
regulation of cellular catabolic process	GO:0031329	101	0.025
regulation of cell proliferation	GO:0042127	359	0.024	Human
nucleoside monophosphate catabolic process	GO:0009125	56	0.024
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.024
cellular ketone metabolic process	GO:0042180	51	0.024
positive regulation of rna biosynthetic process	GO:1902680	197	0.024	Human
response to nutrient levels	GO:0031667	370	0.024
purine ribonucleoside metabolic process	GO:0046128	168	0.024
positive regulation of developmental process	GO:0051094	283	0.024
macromolecular complex subunit organization	GO:0043933	339	0.024
purine ribonucleoside catabolic process	GO:0046130	124	0.024
eye morphogenesis	GO:0048592	4	0.023
response to wounding	GO:0009611	254	0.023
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.023	Human
nucleoside monophosphate metabolic process	GO:0009123	93	0.023
golgi vesicle transport	GO:0048193	22	0.023
regulation of cellular ketone metabolic process	GO:0010565	27	0.023
single organism organelle organization	GO:1902589	180	0.023
regulation of multicellular organismal development	GO:2000026	376	0.022
organelle organization	GO:0006996	266	0.022
negative regulation of rna biosynthetic process	GO:1902679	118	0.022
anatomical structure morphogenesis	GO:0009653	298	0.022
nucleic acid templated transcription	GO:0097659	379	0.022	Human
positive regulation of transcription dna templated	GO:0045893	197	0.021	Human
single organism reproductive process	GO:0044702	297	0.021
negative regulation of developmental process	GO:0051093	125	0.021
neuron projection development	GO:0031175	273	0.021
neuron differentiation	GO:0030182	368	0.021
negative regulation of multicellular organismal process	GO:0051241	203	0.021
positive regulation of phosphorylation	GO:0042327	177	0.021
regulation of phosphate metabolic process	GO:0019220	349	0.021
heterocycle catabolic process	GO:0046700	167	0.021
nucleoside metabolic process	GO:0009116	179	0.021
cellular component movement	GO:0006928	248	0.020	Human
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.020
negative regulation of transcription dna templated	GO:0045892	116	0.020
protein complex assembly	GO:0006461	263	0.020
cellular amine metabolic process	GO:0044106	38	0.020
negative regulation of gene expression	GO:0010629	199	0.020
protein localization	GO:0008104	191	0.020	Human
ribonucleoside catabolic process	GO:0042454	126	0.020
regulation of cellular amino acid metabolic process	GO:0006521	2	0.020
negative regulation of biosynthetic process	GO:0009890	168	0.019
nucleotide catabolic process	GO:0009166	139	0.019
nucleoside catabolic process	GO:0009164	126	0.018
blood circulation	GO:0008015	183	0.018
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.018
reproductive structure development	GO:0048608	128	0.018
protein secretion	GO:0009306	34	0.018
regulation of phosphorus metabolic process	GO:0051174	349	0.018
telencephalon development	GO:0021537	62	0.018
macromolecular complex assembly	GO:0065003	273	0.018
positive regulation of apoptotic process	GO:0043065	154	0.017
positive regulation of molecular function	GO:0044093	230	0.017	Human
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.017
response to oxidative stress	GO:0006979	186	0.017
transcription from rna polymerase ii promoter	GO:0006366	252	0.017	Human
nucleobase containing compound catabolic process	GO:0034655	152	0.017
anion transport	GO:0006820	178	0.017
nucleoside phosphate catabolic process	GO:1901292	140	0.017
positive regulation of rna metabolic process	GO:0051254	203	0.017	Human
amine metabolic process	GO:0009308	38	0.017
circulatory system process	GO:0003013	183	0.016
golgi organization	GO:0007030	17	0.016
negative regulation of cellular protein metabolic process	GO:0032269	106	0.016
gonad development	GO:0008406	104	0.016
glycosyl compound catabolic process	GO:1901658	126	0.016
negative regulation of protein metabolic process	GO:0051248	114	0.016
regulation of cell differentiation	GO:0045595	320	0.016
tissue development	GO:0009888	252	0.016
regulation of anatomical structure size	GO:0090066	135	0.016
regulation of purine nucleotide metabolic process	GO:1900542	115	0.016
positive regulation of cell death	GO:0010942	184	0.016
positive regulation of phosphorus metabolic process	GO:0010562	262	0.016
ras protein signal transduction	GO:0007265	29	0.016
cation transport	GO:0006812	382	0.015	Human
negative regulation of transport	GO:0051051	136	0.015	Human
organ morphogenesis	GO:0009887	75	0.015
regulation of neuron differentiation	GO:0045664	208	0.015
response to metal ion	GO:0010038	253	0.015
sex differentiation	GO:0007548	113	0.015
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.015
regulation of cellular protein metabolic process	GO:0032268	267	0.015
multicellular organismal reproductive process	GO:0048609	233	0.015
locomotion	GO:0040011	237	0.015	Human
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.015
regulation of cell development	GO:0060284	263	0.014
small molecule biosynthetic process	GO:0044283	124	0.014
er to golgi vesicle mediated transport	GO:0006888	10	0.014
development of primary sexual characteristics	GO:0045137	107	0.014
cell growth	GO:0016049	104	0.014	Human
intracellular signal transduction	GO:0035556	314	0.014
oxidation reduction process	GO:0055114	304	0.014
negative regulation of response to stimulus	GO:0048585	155	0.014
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.014
multi organism reproductive process	GO:0044703	262	0.014
forebrain development	GO:0030900	98	0.014
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.014	Human
neuron development	GO:0048666	286	0.014
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.014	Human
vascular process in circulatory system	GO:0003018	96	0.014
membrane fusion	GO:0061025	26	0.013
positive regulation of hydrolase activity	GO:0051345	86	0.013	Human
biological adhesion	GO:0022610	110	0.013
response to acid chemical	GO:0001101	222	0.013
protein complex subunit organization	GO:0071822	302	0.013
negative regulation of metabolic process	GO:0009892	331	0.013
response to axon injury	GO:0048678	59	0.013
cellular component biogenesis	GO:0044085	368	0.013
negative regulation of cellular biosynthetic process	GO:0031327	161	0.013
response to peptide hormone	GO:0043434	278	0.013
cell cycle	GO:0007049	101	0.013
negative regulation of cell death	GO:0060548	229	0.013
multicellular organism reproduction	GO:0032504	233	0.013
protein complex biogenesis	GO:0070271	263	0.013
regulation of cell projection organization	GO:0031344	175	0.013
positive regulation of protein phosphorylation	GO:0001934	135	0.012
positive regulation of cell differentiation	GO:0045597	217	0.012
sexual reproduction	GO:0019953	148	0.012
gtp metabolic process	GO:0046039	72	0.012
regulation of cellular amine metabolic process	GO:0033238	8	0.012
axis specification	GO:0009798	4	0.012
regulation of nervous system development	GO:0051960	264	0.012
negative regulation of programmed cell death	GO:0043069	183	0.012
negative regulation of apoptotic process	GO:0043066	181	0.012
cytoskeleton organization	GO:0007010	111	0.012
multicellular organismal signaling	GO:0035637	44	0.012
carbohydrate metabolic process	GO:0005975	130	0.012
regulation of phosphorylation	GO:0042325	248	0.012
protein catabolic process	GO:0030163	30	0.012
hepaticobiliary system development	GO:0061008	90	0.012
negative regulation of protein maturation	GO:1903318	47	0.012
intracellular protein transport	GO:0006886	79	0.012	Human
positive regulation of multicellular organismal process	GO:0051240	387	0.012
nitrogen compound transport	GO:0071705	229	0.012
vesicle mediated transport	GO:0016192	181	0.012
transmission of nerve impulse	GO:0019226	42	0.012
cellular nitrogen compound catabolic process	GO:0044270	163	0.012
cellular component assembly	GO:0022607	360	0.012
response to oxygen levels	GO:0070482	265	0.012
regulation of signal transduction	GO:0009966	318	0.012
regulation of system process	GO:0044057	208	0.011
cellular response to oxygen containing compound	GO:1901701	386	0.011
regulation of neuron death	GO:1901214	115	0.011
neuronal action potential	GO:0019228	35	0.011
organonitrogen compound biosynthetic process	GO:1901566	167	0.011
metal ion homeostasis	GO:0055065	186	0.011
regulation of nucleotide metabolic process	GO:0006140	117	0.011
negative regulation of molecular function	GO:0044092	133	0.011	Human
response to cytokine	GO:0034097	215	0.011
regulation of body fluid levels	GO:0050878	90	0.011
regulation of cell growth	GO:0001558	85	0.011	Human
protein phosphorylation	GO:0006468	345	0.011
negative regulation of catalytic activity	GO:0043086	103	0.011
organic anion transport	GO:0015711	132	0.011
negative regulation of cell proliferation	GO:0008285	119	0.011
single organism carbohydrate metabolic process	GO:0044723	118	0.011
gland development	GO:0048732	155	0.011
small gtpase mediated signal transduction	GO:0007264	36	0.011
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.011
negative regulation of cell development	GO:0010721	82	0.011
neurological system process	GO:0050877	219	0.011
lipid storage	GO:0019915	1	0.011
response to estrogen	GO:0043627	232	0.011
regulation of blood pressure	GO:0008217	83	0.010
male gamete generation	GO:0048232	99	0.010
spermatogenesis	GO:0007283	99	0.010
rna localization	GO:0006403	4	0.010
regulation of proteolysis	GO:0030162	66	0.010
response to decreased oxygen levels	GO:0036293	237	0.010

Creb3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	nervous system disease	DOID:863	0	0.029
	disease of anatomical entity	DOID:7	0	0.029

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