Rattus norvegicus

0 known processes

Fam46a

family with sequence similarity 46, member A

(Aliases: RGD1311381)

Fam46a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell proliferationGO:00421273590.204
response to cytokineGO:00340972150.164
immune system processGO:00023762040.154
positive regulation of cell deathGO:00109421840.136
regulation of secretionGO:00510462240.136
programmed cell deathGO:00125013920.128
rna metabolic processGO:00160704060.123
regulation of cellular protein metabolic processGO:00322682670.122
transcription dna templatedGO:00063513770.120
regulation of protein metabolic processGO:00512462890.112
response to biotic stimulusGO:00096072260.112
regulation of transcription dna templatedGO:00063553740.106
nucleic acid templated transcriptionGO:00976593790.106
regulation of rna metabolic processGO:00512523910.102
response to bacteriumGO:00096172000.100
negative regulation of cell proliferationGO:00082851190.097
regulation of phosphorus metabolic processGO:00511743490.095
regulation of programmed cell deathGO:00430673410.094
positive regulation of nitrogen compound metabolic processGO:00511733340.094
regulation of nucleic acid templated transcriptionGO:19035063800.092
rna biosynthetic processGO:00327743800.092
response to other organismGO:00517072200.091
positive regulation of multicellular organismal processGO:00512403870.086
secretion by cellGO:00329402480.085
regulation of molecular functionGO:00650093980.084
regulation of signal transductionGO:00099663180.084
apoptotic processGO:00069153810.082
response to molecule of bacterial originGO:00022371940.081
reproductive processGO:00224143720.077
positive regulation of developmental processGO:00510942830.074
response to estrogenGO:00436272320.074
defense responseGO:00069521940.072
cellular response to oxygen containing compoundGO:19017013860.072
negative regulation of metabolic processGO:00098923310.071
response to external biotic stimulusGO:00432072210.071
transcription from rna polymerase ii promoterGO:00063662520.071
catabolic processGO:00090563510.070
protein phosphorylationGO:00064683450.070
regulation of catalytic activityGO:00507903040.068
positive regulation of nucleobase containing compound metabolic processGO:00459353190.068
regulation of protein modification processGO:00313991940.066
regulation of multicellular organismal developmentGO:20000263760.065
cell activationGO:0001775970.065
response to oxygen levelsGO:00704822650.065
positive regulation of programmed cell deathGO:00430681570.065
multi organism reproductive processGO:00447032620.064
carbohydrate derivative metabolic processGO:19011353460.064
regulation of rna biosynthetic processGO:20011413810.064
response to inorganic substanceGO:00100353770.063
response to peptide hormoneGO:00434342780.061
intracellular signal transductionGO:00355563140.060
response to hypoxiaGO:00016662310.060
nucleoside phosphate metabolic processGO:00067532830.059
cellular catabolic processGO:00442482950.057
cellular response to endogenous stimulusGO:00714953770.056
positive regulation of rna metabolic processGO:00512542030.056
negative regulation of macromolecule metabolic processGO:00106052600.055
organic substance catabolic processGO:19015753160.055
multi multicellular organism processGO:00447061380.053
cellular response to organic cyclic compoundGO:00714072020.053
negative regulation of nitrogen compound metabolic processGO:00511721610.053
regulation of phosphorylationGO:00423252480.053
response to peptideGO:19016522920.052
cellular response to hormone stimulusGO:00328702470.052
positive regulation of cell proliferationGO:00082842490.051
response to oxidative stressGO:00069791860.051
response to woundingGO:00096112540.051
Human
positive regulation of rna biosynthetic processGO:19026801970.051
positive regulation of response to stimulusGO:00485842850.051
regulation of immune system processGO:00026821230.051
cellular response to stressGO:00335542690.050
intracellular transportGO:00469071850.050
regulation of phosphate metabolic processGO:00192203490.049
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.049
response to acid chemicalGO:00011012220.049
positive regulation of cell communicationGO:00106472710.049
cellular response to lipidGO:00713962010.048
regulation of apoptotic processGO:00429813350.047
organophosphate metabolic processGO:00196373700.046
negative regulation of multicellular organismal processGO:00512412030.046
response to retinoic acidGO:0032526630.046
secretionGO:00469033070.046
positive regulation of cellular biosynthetic processGO:00313282950.045
positive regulation of secretion by cellGO:19035321280.044
response to estradiolGO:00323551640.044
agingGO:00075682410.044
cellular amino acid metabolic processGO:00065201070.044
female pregnancyGO:00075651220.044
single organism reproductive processGO:00447022970.043
inflammatory responseGO:00069541500.043
positive regulation of biosynthetic processGO:00098913190.043
regulation of cellular amine metabolic processGO:003323880.043
anatomical structure morphogenesisGO:00096532980.043
regulation of intracellular signal transductionGO:19025312180.042
multicellular organism reproductionGO:00325042330.042
reproductive structure developmentGO:00486081280.042
negative regulation of signalingGO:00230571570.042
regulation of transcription from rna polymerase ii promoterGO:00063572340.042
response to mechanical stimulusGO:00096121340.042
positive regulation of apoptotic processGO:00430651540.041
cellular calcium ion homeostasisGO:00068741600.041
positive regulation of nucleic acid templated transcriptionGO:19035081970.041
positive regulation of catalytic activityGO:00430851840.041
hormone transportGO:00099141210.040
reproductionGO:00000032450.040
oxoacid metabolic processGO:00434362900.040
protein transportGO:00150311320.039
blood circulationGO:00080151830.039
positive regulation of cellular protein metabolic processGO:00322701670.039
positive regulation of molecular functionGO:00440932300.039
cell cell signalingGO:00072673350.039
response to lipopolysaccharideGO:00324961910.038
cellular response to organonitrogen compoundGO:00714171970.038
organic acid metabolic processGO:00060822920.038
positive regulation of signalingGO:00230562700.038
cellular component movementGO:00069282480.038
cell migrationGO:00164771970.038
regulation of protein phosphorylationGO:00019321830.038
regulation of secretion by cellGO:19035302080.038
cellular response to tumor necrosis factorGO:0071356460.037
response to ketoneGO:19016541820.037
single organism catabolic processGO:00447122830.037
positive regulation of macromolecule biosynthetic processGO:00105572470.037
ion homeostasisGO:00508012120.037
localization of cellGO:00516742020.036
positive regulation of cell differentiationGO:00455972170.036
positive regulation of transcription dna templatedGO:00458931970.036
response to decreased oxygen levelsGO:00362932370.036
response to corticosteroidGO:00319602350.036
macromolecular complex subunit organizationGO:00439333390.035
nucleotide metabolic processGO:00091172790.035
carboxylic acid metabolic processGO:00197522890.035
regulation of cellular localizationGO:00603412630.035
forebrain developmentGO:0030900980.035
ribonucleotide metabolic processGO:00092592310.034
response to alkaloidGO:00432791320.034
glycosyl compound metabolic processGO:19016571820.034
regulation of hydrolase activityGO:00513361430.034
negative regulation of cellular metabolic processGO:00313242810.034
response to interleukin 1GO:0070555550.033
regulation of cell developmentGO:00602842630.033
negative regulation of gene expressionGO:00106291990.033
protein localizationGO:00081041910.032
anterior posterior pattern specificationGO:000995210.032
response to heatGO:0009408600.032
cellular response to cytokine stimulusGO:00713451270.032
immune responseGO:00069551040.032
cellular ketone metabolic processGO:0042180510.032
regenerationGO:00310991630.032
purine ribonucleotide metabolic processGO:00091502270.032
metal ion homeostasisGO:00550651860.032
regulation of tube sizeGO:0035150890.031
cellular chemical homeostasisGO:00550822470.031
positive regulation of signal transductionGO:00099671750.031
homeostatic processGO:00425923310.031
nitrogen compound transportGO:00717052290.031
macromolecule localizationGO:00330362520.031
positive regulation of secretionGO:00510471400.031
response to hexoseGO:00097461440.030
response to nutrient levelsGO:00316673700.030
cellular homeostasisGO:00197252520.030
neuron deathGO:00709971270.030
purine nucleotide metabolic processGO:00061632290.030
neuron developmentGO:00486662860.030
cardiovascular system developmentGO:00723581340.030
positive regulation of phosphorus metabolic processGO:00105622620.030
protein oligomerizationGO:00512591910.030
negative regulation of cell communicationGO:00106481580.030
negative regulation of protein metabolic processGO:00512481140.030
negative regulation of cell deathGO:00605482290.029
cytokine productionGO:0001816610.029
cellular component assemblyGO:00226073600.029
organonitrogen compound catabolic processGO:19015651790.029
regulation of hormone levelsGO:00108171870.029
positive regulation of cytosolic calcium ion concentrationGO:00072041220.029
regulation of cellular component organizationGO:00511283680.029
lipid metabolic processGO:00066292830.029
positive regulation of intracellular signal transductionGO:19025331380.029
protein complex assemblyGO:00064612630.029
regulation of cell differentiationGO:00455953200.028
signal releaseGO:00230611450.028
vascular process in circulatory systemGO:0003018960.028
single organism intracellular transportGO:19025821660.028
circulatory system developmentGO:00723591340.028
calcium ion homeostasisGO:00550741620.028
ribonucleotide catabolic processGO:00092611360.028
regulation of cellular ketone metabolic processGO:0010565270.028
chemical homeostasisGO:00488782920.027
regulation of cellular amino acid metabolic processGO:000652120.027
central nervous system developmentGO:00074173110.027
organic cyclic compound catabolic processGO:19013611750.027
cellular amine metabolic processGO:0044106380.027
neuron differentiationGO:00301823680.027
ribose phosphate metabolic processGO:00196932350.027
cation homeostasisGO:00550801950.027
response to nutrientGO:00075842480.026
positive regulation of protein metabolic processGO:00512471780.026
divalent metal ion transportGO:00708381320.026
monocarboxylic acid metabolic processGO:00327871520.026
negative regulation of apoptotic processGO:00430661810.026
response to temperature stimulusGO:0009266940.026
response to glucoseGO:00097491360.026
multicellular organismal reproductive processGO:00486092330.026
leukocyte activationGO:0045321760.026
cellular cation homeostasisGO:00300031800.026
hormone secretionGO:00468791150.025
positive regulation of protein modification processGO:00314011420.025
amine metabolic processGO:0009308380.025
organ regenerationGO:00311001010.025
purine containing compound metabolic processGO:00725212530.025
response to tumor necrosis factorGO:0034612560.025
brain developmentGO:00074202470.025
response to glucocorticoidGO:00513842230.025
cytosolic calcium ion homeostasisGO:00514801400.025
response to hydrogen peroxideGO:0042542890.024
positive regulation of gene expressionGO:00106282440.024
cellular response to external stimulusGO:00714961180.024
regulation of protein kinase activityGO:00458591050.024
head developmentGO:00603222470.024
aromatic compound catabolic processGO:00194391680.024
negative regulation of response to stimulusGO:00485851550.024
regulation of cell motilityGO:20001451310.024
nucleobase containing small molecule metabolic processGO:00550863160.024
regulation of cytokine productionGO:0001817560.024
vasculature developmentGO:0001944700.024
establishment of protein localizationGO:00451841410.024
cation transportGO:00068123820.024
positive regulation of neurogenesisGO:00507691650.023
organ morphogenesisGO:0009887750.023
tissue developmentGO:00098882520.023
proteolysisGO:00065081750.023
regulation of immune responseGO:0050776550.023
negative regulation of programmed cell deathGO:00430691830.023
heterocycle catabolic processGO:00467001670.023
immune effector processGO:0002252530.023
g protein coupled receptor signaling pathwayGO:00071862420.023
development of primary female sexual characteristicsGO:0046545560.022
cell motilityGO:00488702020.022
neuron projection developmentGO:00311752730.022
cellular metal ion homeostasisGO:00068751720.022
positive regulation of cytokine productionGO:0001819420.022
negative regulation of nucleobase containing compound metabolic processGO:00459341530.022
gland developmentGO:00487321550.022
protein complex biogenesisGO:00702712630.022
mesenchymal cell proliferationGO:001046340.022
purine ribonucleotide catabolic processGO:00091541360.022
protein secretionGO:0009306340.022
regulation of transferase activityGO:00513381230.022
organophosphate biosynthetic processGO:00904071430.022
cellular divalent inorganic cation homeostasisGO:00725031620.022
sexual reproductionGO:00199531480.021
gamete generationGO:00072761240.021
positive regulation of phosphate metabolic processGO:00459372620.021
negative regulation of cellular protein metabolic processGO:00322691060.021
carbohydrate metabolic processGO:00059751300.021
mapk cascadeGO:00001651400.021
regulation of canonical wnt signaling pathwayGO:006082840.021
nucleotide biosynthetic processGO:0009165980.021
purine nucleotide biosynthetic processGO:0006164830.021
nucleoside phosphate catabolic processGO:19012921400.021
cellular response to abiotic stimulusGO:0071214850.021
developmental process involved in reproductionGO:00030061590.021
cellular response to nitrogen compoundGO:19016992100.021
reproductive system developmentGO:00614581280.021
divalent inorganic cation homeostasisGO:00725071650.020
signal transduction by phosphorylationGO:00230141440.020
regulation of locomotionGO:00400121480.020
b cell mediated immunityGO:001972440.020
response to monosaccharideGO:00342841590.020
positive regulation of cell developmentGO:00107201760.020
metal ion transportGO:00300012890.020
positive regulation of protein phosphorylationGO:00019341350.020
positive regulation of transportGO:00510502450.020
protein complex subunit organizationGO:00718223020.020
response to metal ionGO:00100382530.020
positive regulation of cellular component organizationGO:00511302000.020
mesoderm developmentGO:000749820.020
calcium ion transportGO:00068161310.019
positive regulation of phosphorylationGO:00423271770.019
response to reactive oxygen speciesGO:00003021200.019
circulatory system processGO:00030131830.019
prostate gland epithelium morphogenesisGO:006074020.019
nucleoside metabolic processGO:00091161790.019
regulation of neuron apoptotic processGO:0043523830.019
cellular response to mechanical stimulusGO:0071260480.019
female gonad developmentGO:0008585530.019
urogenital system developmentGO:0001655780.019
positive regulation of immune system processGO:0002684900.019
eye morphogenesisGO:004859240.019
cell projection organizationGO:00300303020.019
regulation of blood vessel sizeGO:0050880890.019
carbohydrate derivative biosynthetic processGO:19011371240.019
myeloid leukocyte activationGO:0002274360.019
cellular response to acid chemicalGO:0071229750.019
oxidation reduction processGO:00551143040.019
response to ethanolGO:00454711620.019
cellular component biogenesisGO:00440853680.019
neurological system processGO:00508772190.019
response to radiationGO:00093141370.018
sex differentiationGO:00075481130.018
carbohydrate derivative catabolic processGO:19011361470.018
negative regulation of rna metabolic processGO:00512531230.018
nucleobase containing compound catabolic processGO:00346551520.018
response to purine containing compoundGO:00140741260.018
regulation of cell activationGO:0050865500.018
regulation of cell migrationGO:00303341280.018
negative regulation of molecular functionGO:00440921330.018
purine ribonucleoside triphosphate metabolic processGO:00092051400.018
negative regulation of macromolecule biosynthetic processGO:00105581480.018
response to transition metal nanoparticleGO:19902671220.018
single organism biosynthetic processGO:00447113420.018
peptidyl tyrosine modificationGO:0018212720.018
regulation of protein secretionGO:0050708280.017
regulation of kinase activityGO:00435491170.017
prostate gland morphogenesisGO:006051220.017
regulation of nervous system developmentGO:00519602640.017
regulation of response to external stimulusGO:00321011060.017
Human
cellular ion homeostasisGO:00068731840.017
response to growth factorGO:00708481890.017
cellular lipid metabolic processGO:00442552080.017
regulation of mapk cascadeGO:00434081160.017
cytoplasmic transportGO:00164821150.017
ribonucleoside triphosphate metabolic processGO:00091991410.017
gonad developmentGO:00084061040.017
sequestering of metal ionGO:005123890.017
ribonucleotide biosynthetic processGO:0009260850.017
muscle cell proliferationGO:0033002840.017
macromolecular complex assemblyGO:00650032730.017
negative regulation of secretionGO:0051048820.016
cellular nitrogen compound catabolic processGO:00442701630.016
regulation of cell adhesionGO:0030155520.016
positive regulation of transferase activityGO:0051347810.016
organonitrogen compound biosynthetic processGO:19015661670.016
exocytosisGO:0006887600.016
negative regulation of phosphate metabolic processGO:0045936800.016
cellular response to peptideGO:19016531330.016
regulation of synaptic transmissionGO:00508041410.016
nucleoside monophosphate metabolic processGO:0009123930.016
camp metabolic processGO:0046058630.016
organophosphate catabolic processGO:00464341480.016
nucleoside phosphate biosynthetic processGO:19012931020.016
ribose phosphate biosynthetic processGO:0046390870.016
regulation of purine nucleotide biosynthetic processGO:1900371460.016
sensory perception of painGO:0019233730.016
rhythmic processGO:00485111560.016
biological adhesionGO:00226101100.016
cyclic nucleotide metabolic processGO:0009187800.016
regulation of protein localizationGO:0032880810.015
ribonucleoside metabolic processGO:00091191740.015
formation of primary germ layerGO:000170410.015
cell adhesionGO:00071551100.015
positive regulation of mapk cascadeGO:0043410920.015
response to extracellular stimulusGO:00099913800.015
nucleoside triphosphate metabolic processGO:00091411440.015
ovulation cycleGO:0042698670.015
behaviorGO:00076102050.015
jak stat cascadeGO:0007259260.015
regulation of leukocyte activationGO:0002694450.015
regulation of neuron deathGO:19012141150.015
positive regulation of nervous system developmentGO:00519621780.015
divalent inorganic cation transportGO:00725111340.015
negative regulation of cellular biosynthetic processGO:00313271610.015
regulation of homeostatic processGO:00328441010.015
single organism behaviorGO:00447081300.015
purine nucleoside catabolic processGO:00061521240.015
negative regulation of transcription dna templatedGO:00458921160.015
cellular response to growth factor stimulusGO:00713631620.015
cell type specific apoptotic processGO:00972851340.015
positive regulation of cellular component movementGO:00512721020.015
regulation of system processGO:00440572080.015
positive regulation of kinase activityGO:0033674770.015
cognitionGO:0050890920.015
axis specificationGO:000979840.015
single organism cellular localizationGO:19025801020.015
regulation of calcium ion transportGO:0051924770.015
regulation of defense responseGO:0031347680.014
purine nucleoside metabolic processGO:00422781690.014
vesicle mediated transportGO:00161921810.014
limb morphogenesisGO:003510840.014
regulation of blood pressureGO:0008217830.014
negative regulation of biosynthetic processGO:00098901680.014
regulation of blood circulationGO:19035221100.014
regulation of anatomical structure sizeGO:00900661350.014
response to carbohydrateGO:00097431830.014
kidney developmentGO:0001822670.014
regulation of nucleotide metabolic processGO:00061401170.014
muscle cell migrationGO:0014812360.014
nucleotide catabolic processGO:00091661390.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
regulation of hormone secretionGO:00468831060.014
cellular response to peptide hormone stimulusGO:00713751200.014
sequestering of calcium ionGO:005120880.014
negative regulation of homeostatic processGO:0032845470.014
regulation of purine nucleotide metabolic processGO:19005421150.014
negative regulation of signal transductionGO:0009968830.013
ovulation cycle processGO:0022602500.013
cellular response to lipopolysaccharideGO:0071222550.013
transmembrane transportGO:00550854120.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.013
cell activation involved in immune responseGO:0002263160.013
purine nucleotide catabolic processGO:00061951360.013
leukocyte activation involved in immune responseGO:0002366160.013
response to activityGO:0014823730.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
positive regulation of smooth muscle cell proliferationGO:0048661510.013
positive regulation of cell motilityGO:2000147970.013
renal system developmentGO:0072001670.013
negative regulation of phosphorus metabolic processGO:0010563800.013
regulation of response to stressGO:00801341260.013
Human
cellular response to steroid hormone stimulusGO:0071383930.013
appendage morphogenesisGO:003510740.013
response to organophosphorusGO:00466831020.013
regulation of cellular component movementGO:00512701500.013
regulation of neurogenesisGO:00507672470.013
purine ribonucleotide biosynthetic processGO:0009152810.013
positive regulation of cellular amine metabolic processGO:003324030.013
positive regulation of neuron differentiationGO:00456661260.013
regulation of ion homeostasisGO:2000021630.013
regulation of establishment of protein localizationGO:0070201690.013
epithelium developmentGO:0060429960.013
protein maturationGO:0051604680.013
smooth muscle cell proliferationGO:0048659770.012
skeletal system developmentGO:0001501410.012
immunoglobulin mediated immune responseGO:001606440.012
locomotionGO:00400112370.012
bmp signaling pathwayGO:003050940.012
ossificationGO:0001503700.012
regulation of fat cell differentiationGO:004559830.012
spermatogenesisGO:0007283990.012
regulation of metal ion transportGO:00109591180.012
negative regulation of catalytic activityGO:00430861030.012
negative regulation of cell cycle phase transitionGO:190198840.012
negative regulation of mitotic cell cycle phase transitionGO:190199130.012
liver developmentGO:0001889900.012
peptide metabolic processGO:0006518320.012
gastrulationGO:000736920.012
peptidyl tyrosine phosphorylationGO:0018108720.012
purine ribonucleoside metabolic processGO:00461281680.012
regulation of smooth muscle cell proliferationGO:0048660750.012
purine containing compound catabolic processGO:00725231380.012
regulation of neuron projection developmentGO:00109751610.012
male gamete generationGO:0048232990.012
negative regulation of transportGO:00510511360.012
regulation of mesenchymal cell proliferationGO:001046440.012
embryonic pattern specificationGO:000988010.012
heart morphogenesisGO:000300730.012
learning or memoryGO:0007611900.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
negative regulation of secretion by cellGO:1903531720.012
negative regulation of rna biosynthetic processGO:19026791180.012
telencephalon developmentGO:0021537620.011
regulation of protein transportGO:0051223680.011
development of primary sexual characteristicsGO:00451371070.011
activation of cysteine type endopeptidase activityGO:009720240.011
positive regulation of blood circulationGO:1903524650.011
regulation of immune effector processGO:0002697320.011
interleukin 1 secretionGO:005070130.011
negative regulation of phosphorylationGO:0042326570.011
synaptic transmissionGO:00072682350.011
regulation of cell cycleGO:0051726730.011
camp biosynthetic processGO:0006171470.011
nucleoside triphosphate catabolic processGO:00091431230.011
response to amino acidGO:0043200750.011
positive regulation of immunoglobulin productionGO:000263940.011
dephosphorylationGO:0016311980.011
peptide hormone secretionGO:0030072840.011
positive regulation of leukocyte degranulationGO:004330240.011
neuron apoptotic processGO:0051402880.011
negative regulation of developmental processGO:00510931250.011
response to testosteroneGO:0033574550.011
second messenger mediated signalingGO:0019932510.011
endocytosisGO:0006897840.011
acute inflammatory responseGO:0002526580.011
lymphocyte activation involved in immune responseGO:000228530.011
dna metabolic processGO:0006259960.011
anatomical structure formation involved in morphogenesisGO:0048646830.011
regulation of inflammatory responseGO:0050727480.011
nucleoside catabolic processGO:00091641260.011
salivary gland developmentGO:000743130.011
regulation of nucleotide biosynthetic processGO:0030808470.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
ribonucleoside catabolic processGO:00424541260.010
regulation of epithelial cell proliferationGO:0050678490.010
glycosyl compound catabolic processGO:19016581260.010

Fam46a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.033
disease of anatomical entityDOID:700.033
musculoskeletal system diseaseDOID:1700.027
connective tissue diseaseDOID:6500.018
bone diseaseDOID:008000100.018
central nervous system diseaseDOID:33100.015
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.015
cancerDOID:16200.015
sensory system diseaseDOID:005015500.013
inherited metabolic disorderDOID:65500.012
disease of metabolismDOID:001466700.012