Rattus norvegicus

60 known processes

Apaf1

apoptotic peptidase activating factor 1

Apaf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to metal ionGO:00100382530.076
positive regulation of nucleobase containing compound metabolic processGO:00459353190.066
programmed cell deathGO:00125013920.063
regulation of interleukin 1 beta secretionGO:005070630.056
regulation of apoptotic processGO:00429813350.053
intracellular signal transductionGO:00355563140.052
positive regulation of gene expressionGO:00106282440.052
regulation of molecular functionGO:00650093980.051
organelle organizationGO:00069962660.050
organophosphate metabolic processGO:00196373700.049
positive regulation of nitrogen compound metabolic processGO:00511733340.049
positive regulation of multicellular organismal processGO:00512403870.049
behaviorGO:00076102050.048
cellular component biogenesisGO:00440853680.047
oxoacid metabolic processGO:00434362900.047
positive regulation of behaviorGO:0048520380.046
positive regulation of developmental processGO:00510942830.046
cellular component assemblyGO:00226073600.046
response to inorganic substanceGO:00100353770.046
head developmentGO:00603222470.045
neuron differentiationGO:00301823680.044
regulation of multicellular organismal developmentGO:20000263760.044
apoptotic processGO:00069153810.044
response to oxidative stressGO:00069791860.044
regulation of transcription dna templatedGO:00063553740.043
response to ketoneGO:19016541820.042
carbohydrate derivative metabolic processGO:19011353460.042
positive regulation of interleukin 1 beta secretionGO:005071830.040
cellular response to hormone stimulusGO:00328702470.040
nucleoside phosphate metabolic processGO:00067532830.039
positive regulation of molecular functionGO:00440932300.038
positive regulation of cell differentiationGO:00455972170.038
macromolecular complex subunit organizationGO:00439333390.037
regulation of catalytic activityGO:00507903040.037
cellular amino acid metabolic processGO:00065201070.037
regulation of phosphate metabolic processGO:00192203490.037
positive regulation of response to stimulusGO:00485842850.036
positive regulation of cell deathGO:00109421840.036
protein complex subunit organizationGO:00718223020.036
response to acid chemicalGO:00011012220.035
response to estrogenGO:00436272320.035
amine metabolic processGO:0009308380.035
regulation of cell differentiationGO:00455953200.035
response to peptide hormoneGO:00434342780.034
protein localizationGO:00081041910.034
positive regulation of cellular protein metabolic processGO:00322701670.034
response to nutrient levelsGO:00316673700.033
regulation of rna metabolic processGO:00512523910.033
anatomical structure morphogenesisGO:00096532980.033
positive regulation of catalytic activityGO:00430851840.033
cellular response to oxygen containing compoundGO:19017013860.033
response to decreased oxygen levelsGO:00362932370.032
positive regulation of retinal cell programmed cell deathGO:004667010.032
regulation of cellular component organizationGO:00511283680.031
small gtpase mediated signal transductionGO:0007264360.031
central nervous system developmentGO:00074173110.031
tissue developmentGO:00098882520.031
carboxylic acid metabolic processGO:00197522890.031
ras protein signal transductionGO:0007265290.030
immune system processGO:00023762040.030
nucleic acid templated transcriptionGO:00976593790.030
positive regulation of cellular biosynthetic processGO:00313282950.030
transcription dna templatedGO:00063513770.030
regulation of cellular protein metabolic processGO:00322682670.030
positive regulation of cell developmentGO:00107201760.030
cellular component movementGO:00069282480.030
protein complex biogenesisGO:00702712630.029
positive regulation of programmed cell deathGO:00430681570.029
interleukin 1 beta secretionGO:005070230.029
organic acid metabolic processGO:00060822920.029
wound healingGO:00420601220.029
single organism biosynthetic processGO:00447113420.029
response to hypoxiaGO:00016662310.029
response to corticosteroidGO:00319602350.029
regulation of cell proliferationGO:00421273590.029
nucleotide metabolic processGO:00091172790.029
proteolysisGO:00065081750.029
rna biosynthetic processGO:00327743800.029
regulation of cellular amino acid metabolic processGO:000652120.028
regulation of cell developmentGO:00602842630.028
protein phosphorylationGO:00064683450.028
single organism reproductive processGO:00447022970.028
eye morphogenesisGO:004859240.028
regulation of programmed cell deathGO:00430673410.028
regulation of phosphorus metabolic processGO:00511743490.028
positive regulation of biosynthetic processGO:00098913190.028
positive regulation of rna biosynthetic processGO:19026801970.027
regulation of secretionGO:00510462240.027
regulation of cell migrationGO:00303341280.027
purine nucleotide metabolic processGO:00061632290.027
purine ribonucleotide metabolic processGO:00091502270.027
rna metabolic processGO:00160704060.027
positive regulation of signalingGO:00230562700.027
regulation of neuron deathGO:19012141150.027
macromolecular complex assemblyGO:00650032730.026
regulation of hydrolase activityGO:00513361430.026
positive regulation of phosphorus metabolic processGO:00105622620.026
positive regulation of macromolecule biosynthetic processGO:00105572470.026
positive regulation of nucleic acid templated transcriptionGO:19035081970.026
response to toxic substanceGO:00096361330.026
cellular amine metabolic processGO:0044106380.026
cellular response to stressGO:00335542690.026
regulation of cellular amine metabolic processGO:003323880.026
positive regulation of cell proliferationGO:00082842490.026
positive regulation of cell communicationGO:00106472710.026
regulation of nucleic acid templated transcriptionGO:19035063800.026
cellular response to organic cyclic compoundGO:00714072020.025
reproductionGO:00000032450.025
locomotionGO:00400112370.025
reproductive processGO:00224143720.025
positive regulation of hydrolase activityGO:0051345860.025
regulation of rna biosynthetic processGO:20011413810.025
positive regulation of phosphate metabolic processGO:00459372620.025
respiratory system developmentGO:0060541450.024
neuron deathGO:00709971270.024
synaptic growth at neuromuscular junctionGO:005112410.024
response to oxygen levelsGO:00704822650.024
negative regulation of cell deathGO:00605482290.024
nucleobase containing small molecule metabolic processGO:00550863160.024
cellular response to endogenous stimulusGO:00714953770.024
multicellular organism reproductionGO:00325042330.024
regulation of immune system processGO:00026821230.024
regulation of intracellular signal transductionGO:19025312180.024
positive regulation of protein metabolic processGO:00512471780.024
response to reactive oxygen speciesGO:00003021200.023
cation transportGO:00068123820.023
cellular response to abiotic stimulusGO:0071214850.023
organophosphate catabolic processGO:00464341480.023
cellular ketone metabolic processGO:0042180510.023
ribonucleotide metabolic processGO:00092592310.023
secretionGO:00469033070.023
nucleoside metabolic processGO:00091161790.023
regulation of cellular ketone metabolic processGO:0010565270.023
brain developmentGO:00074202470.023
purine containing compound catabolic processGO:00725231380.022
regulation of nervous system developmentGO:00519602640.022
positive regulation of transcription dna templatedGO:00458931970.022
positive regulation of rna metabolic processGO:00512542030.022
localization of cellGO:00516742020.022
response to ethanolGO:00454711620.022
lipid metabolic processGO:00066292830.022
organic cyclic compound catabolic processGO:19013611750.022
single organism catabolic processGO:00447122830.021
metal ion transportGO:00300012890.021
response to glucocorticoidGO:00513842230.021
regulation of protein modification processGO:00313991940.021
response to woundingGO:00096112540.021
regulation of phosphorylationGO:00423252480.021
ribose phosphate metabolic processGO:00196932350.021
multicellular organismal reproductive processGO:00486092330.021
growthGO:00400071650.021
regulation of neuron apoptotic processGO:0043523830.020
cell projection organizationGO:00300303020.020
regulation of protein metabolic processGO:00512462890.020
organonitrogen compound catabolic processGO:19015651790.020
heterocycle catabolic processGO:00467001670.020
cellular nitrogen compound catabolic processGO:00442701630.020
positive regulation of intracellular signal transductionGO:19025331380.020
positive regulation of apoptotic processGO:00430651540.020
cellular response to growth factor stimulusGO:00713631620.020
nucleoside phosphate catabolic processGO:19012921400.020
development of primary sexual characteristicsGO:00451371070.020
ribonucleoside metabolic processGO:00091191740.020
regulation of cell motilityGO:20001451310.020
response to antibioticGO:0046677390.019
response to extracellular stimulusGO:00099913800.019
response to hexoseGO:00097461440.019
regulation of signal transductionGO:00099663180.019
leukocyte activationGO:0045321760.019
carbohydrate derivative catabolic processGO:19011361470.019
catabolic processGO:00090563510.019
ribonucleoside catabolic processGO:00424541260.019
negative regulation of programmed cell deathGO:00430691830.019
regulation of neurogenesisGO:00507672470.019
neuron projection developmentGO:00311752730.019
response to ionizing radiationGO:0010212590.019
purine ribonucleotide catabolic processGO:00091541360.019
multi organism reproductive processGO:00447032620.019
regulation of cellular component movementGO:00512701500.019
protein complex assemblyGO:00064612630.019
response to growth factorGO:00708481890.019
response to radiationGO:00093141370.019
purine containing compound metabolic processGO:00725212530.019
neurological system processGO:00508772190.019
establishment of protein localizationGO:00451841410.019
reproductive structure developmentGO:00486081280.019
macromolecule localizationGO:00330362520.018
response to monosaccharideGO:00342841590.018
cellular response to nitrogen compoundGO:19016992100.018
cell activationGO:0001775970.018
signal transduction by phosphorylationGO:00230141440.018
positive regulation of interleukin 1 secretionGO:005071630.018
positive regulation of protein modification processGO:00314011420.018
homeostatic processGO:00425923310.018
positive regulation of cellular amine metabolic processGO:003324030.018
positive regulation of neurogenesisGO:00507691650.018
regulation of locomotionGO:00400121480.018
regulation of secretion by cellGO:19035302080.018
response to estradiolGO:00323551640.018
positive regulation of transportGO:00510502450.018
regulation of anatomical structure morphogenesisGO:00226031410.018
cytokine productionGO:0001816610.018
response to cobalt ionGO:0032025120.018
cellular response to lipidGO:00713962010.018
response to cytokineGO:00340972150.018
glycosyl compound metabolic processGO:19016571820.018
transcription from rna polymerase ii promoterGO:00063662520.018
positive regulation of nervous system developmentGO:00519621780.018
neuron apoptotic processGO:0051402880.017
cation homeostasisGO:00550801950.017
agingGO:00075682410.017
tube developmentGO:0035295890.017
limbic system developmentGO:0021761380.017
regulation of system processGO:00440572080.017
response to amino acidGO:0043200750.017
lens development in camera type eyeGO:0002088130.017
response to peptideGO:19016522920.017
response to transition metal nanoparticleGO:19902671220.017
protein autophosphorylationGO:0046777660.017
regulation of purine nucleotide catabolic processGO:0033121650.017
cellular response to peptideGO:19016531330.017
response to carbohydrateGO:00097431830.017
negative regulation of metabolic processGO:00098923310.017
response to hydrogen peroxideGO:0042542890.017
nucleoside triphosphate metabolic processGO:00091411440.017
purine ribonucleoside triphosphate catabolic processGO:00092071220.017
axis specificationGO:000979840.016
protein transportGO:00150311320.016
purine nucleotide catabolic processGO:00061951360.016
regulation of response to stressGO:00801341260.016
positive regulation of phosphorylationGO:00423271770.016
regulation of membrane potentialGO:00423911100.016
cell type specific apoptotic processGO:00972851340.016
cell motilityGO:00488702020.016
nucleobase containing compound catabolic processGO:00346551520.016
secretion by cellGO:00329402480.016
forebrain developmentGO:0030900980.016
negative regulation of cellular metabolic processGO:00313242810.016
chemical homeostasisGO:00488782920.016
ribonucleotide catabolic processGO:00092611360.016
single organism carbohydrate metabolic processGO:00447231180.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.015
positive regulation of cytokine productionGO:0001819420.015
cellular ion homeostasisGO:00068731840.015
positive regulation of signal transductionGO:00099671750.015
response to nutrientGO:00075842480.015
regulation of interleukin 1 secretionGO:005070430.015
protein heterooligomerizationGO:0051291890.015
response to molecule of bacterial originGO:00022371940.015
circulatory system processGO:00030131830.015
regulation of anatomical structure sizeGO:00900661350.015
sex differentiationGO:00075481130.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
aromatic compound catabolic processGO:00194391680.015
organ morphogenesisGO:0009887750.015
cell cell signalingGO:00072673350.015
single organism organelle organizationGO:19025891800.015
negative regulation of signalingGO:00230571570.015
intracellular transportGO:00469071850.015
sensory organ developmentGO:0007423740.015
regulation of retinal cell programmed cell deathGO:004666810.015
regulation of ion transportGO:00432692450.015
memoryGO:0007613540.015
positive regulation of protein phosphorylationGO:00019341350.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
negative regulation of apoptotic processGO:00430661810.014
purine nucleoside metabolic processGO:00422781690.014
anterior posterior pattern specificationGO:000995210.014
cell migrationGO:00164771970.014
regulation of protein phosphorylationGO:00019321830.014
regulation of nucleotide metabolic processGO:00061401170.014
immune responseGO:00069551040.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
purine nucleoside catabolic processGO:00061521240.014
carbohydrate derivative biosynthetic processGO:19011371240.014
single organism behaviorGO:00447081300.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
negative regulation of response to stimulusGO:00485851550.014
cellular response to steroid hormone stimulusGO:0071383930.014
positive regulation of purine nucleotide metabolic processGO:1900544910.014
developmental process involved in reproductionGO:00030061590.014
negative regulation of cell communicationGO:00106481580.014
positive regulation of cellular component organizationGO:00511302000.014
response to anoxiaGO:003405940.014
ribonucleoside triphosphate metabolic processGO:00091991410.014
cellular homeostasisGO:00197252520.013
actin filament based processGO:0030029860.013
eye developmentGO:0001654500.013
lung developmentGO:0030324430.013
response to temperature stimulusGO:0009266940.013
divalent inorganic cation homeostasisGO:00725071650.013
positive regulation of secretionGO:00510471400.013
glycosyl compound catabolic processGO:19016581260.013
cell morphogenesisGO:00009021420.013
regulation of cellular localizationGO:00603412630.013
metal ion homeostasisGO:00550651860.013
regulation of protein kinase activityGO:00458591050.013
response to transforming growth factor betaGO:0071559460.013
negative regulation of macromolecule metabolic processGO:00106052600.013
nucleotide catabolic processGO:00091661390.013
positive regulation of nucleotide metabolic processGO:0045981910.013
response to heatGO:0009408600.013
cellular catabolic processGO:00442482950.013
telencephalon developmentGO:0021537620.013
organic substance catabolic processGO:19015753160.013
regulation of response to external stimulusGO:00321011060.013
mapk cascadeGO:00001651400.013
regulation of kinase activityGO:00435491170.013
myeloid leukocyte activationGO:0002274360.013
digestive system developmentGO:0055123410.013
acute inflammatory response to non antigenic stimulusGO:000252520.013
gastrulationGO:000736920.013
regulation of mapk cascadeGO:00434081160.013
purine ribonucleoside catabolic processGO:00461301240.013
cellular response to external stimulusGO:00714961180.013
cognitionGO:0050890920.013
developmental growthGO:00485891000.013
neuron developmentGO:00486662860.012
regulation of nucleotide catabolic processGO:0030811650.012
anatomical structure formation involved in morphogenesisGO:0048646830.012
defense responseGO:00069521940.012
cellular response to organonitrogen compoundGO:00714171970.012
ovulation cycle processGO:0022602500.012
chromosome segregationGO:000705920.012
negative regulation of gene expressionGO:00106291990.012
ovulation cycleGO:0042698670.012
protein processingGO:0016485680.012
organonitrogen compound biosynthetic processGO:19015661670.012
regulation of transferase activityGO:00513381230.012
regulation of growthGO:00400081050.012
nucleoside catabolic processGO:00091641260.012
purine ribonucleoside triphosphate metabolic processGO:00092051400.012
rho protein signal transductionGO:0007266110.012
gonad developmentGO:00084061040.012
positive regulation of locomotionGO:00400171020.012
negative regulation of transportGO:00510511360.012
rhythmic processGO:00485111560.012
regulation of purine nucleotide metabolic processGO:19005421150.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
hippocampus developmentGO:0021766300.012
regulation of cellular catabolic processGO:00313291010.012
cell projection morphogenesisGO:00488581230.012
maintenance of locationGO:0051235170.012
response to testosteroneGO:0033574550.012
purine nucleoside triphosphate catabolic processGO:00091461220.012
microglial cell activationGO:0001774140.012
protein maturationGO:0051604680.012
biological adhesionGO:00226101100.011
positive regulation of ras gtpase activityGO:0032320280.011
positive regulation of purine nucleotide catabolic processGO:0033123530.011
response to mechanical stimulusGO:00096121340.011
cell morphogenesis involved in differentiationGO:00009041190.011
sexual reproductionGO:00199531480.011
carbohydrate metabolic processGO:00059751300.011
muscle system processGO:00030121150.011
nucleoside triphosphate catabolic processGO:00091431230.011
gamete generationGO:00072761240.011
purine ribonucleoside metabolic processGO:00461281680.011
cellular response to alcoholGO:0097306870.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
response to glucoseGO:00097491360.011
peptidyl amino acid modificationGO:00181931260.011
positive regulation of neuron deathGO:1901216430.011
cellular divalent inorganic cation homeostasisGO:00725031620.011
positive regulation of neuron differentiationGO:00456661260.011
inflammatory responseGO:00069541500.011
positive regulation of gtpase activityGO:0043547470.011
single organism intracellular transportGO:19025821660.011
response to nicotineGO:0035094510.011
cytoplasmic transportGO:00164821150.011
calcium ion homeostasisGO:00550741620.011
cellular lipid metabolic processGO:00442552080.011
response to vitaminGO:00332731310.011
positive regulation of t cell mediated cytotoxicityGO:000191640.011
ion homeostasisGO:00508012120.011
multicellular organism growthGO:003526410.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
apoptotic signaling pathwayGO:0097190270.011
response to other organismGO:00517072200.011
formation of primary germ layerGO:000170410.011
cellular calcium ion homeostasisGO:00068741600.011
response to lipopolysaccharideGO:00324961910.011
regulation of neuron differentiationGO:00456642080.011
cellular metal ion homeostasisGO:00068751720.010
ion transmembrane transportGO:00342203650.010
syncytium formation by plasma membrane fusionGO:000076830.010
myoblast fusionGO:000752020.010
response to bacteriumGO:00096172000.010
spindle organizationGO:000705120.010
blood circulationGO:00080151830.010
organophosphate biosynthetic processGO:00904071430.010
regulation of gtpase activityGO:0043087570.010
adult locomotory behaviorGO:000834440.010
positive regulation of mapk cascadeGO:0043410920.010
regulation of catabolic processGO:00098941130.010
regulation of chemotaxisGO:0050920290.010
cell adhesionGO:00071551100.010
reproductive system developmentGO:00614581280.010
learning or memoryGO:0007611900.010
positive regulation of catabolic processGO:0009896780.010
cellular response to extracellular stimulusGO:0031668730.010
syncytium formationGO:000694940.010
response to alkaloidGO:00432791320.010
meiotic cell cycle processGO:190304630.010
activation of cysteine type endopeptidase activityGO:009720240.010
regulation of nucleoside metabolic processGO:0009118660.010

Apaf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.012
disease of anatomical entityDOID:700.012
disease of cellular proliferationDOID:1456600.010