IMP: Integrative Multi-species Prediction

Rattus norvegicus

7 known processes

Cdh3

cadherin 3

Entrez: 116777
Ensembl: ENSRNOG00000020129
RGD: 621089

Process Predictions
Disease Predictions

Cdh3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of cell proliferation	GO:0042127	359	0.261	Human
positive regulation of multicellular organismal process	GO:0051240	387	0.105
regulation of rna metabolic process	GO:0051252	391	0.085
tissue development	GO:0009888	252	0.084	Human
cellular response to endogenous stimulus	GO:0071495	377	0.084
anterior posterior pattern specification	GO:0009952	1	0.080
neuron development	GO:0048666	286	0.078	Rat
cellular response to nitrogen compound	GO:1901699	210	0.077
regulation of nucleic acid templated transcription	GO:1903506	380	0.069
single organism reproductive process	GO:0044702	297	0.061
nucleic acid templated transcription	GO:0097659	379	0.061
positive regulation of apoptotic process	GO:0043065	154	0.059
gland development	GO:0048732	155	0.058	Rat
cellular response to organic cyclic compound	GO:0071407	202	0.054
intracellular signal transduction	GO:0035556	314	0.053	Rat
positive regulation of programmed cell death	GO:0043068	157	0.052
positive regulation of cell death	GO:0010942	184	0.051
response to wounding	GO:0009611	254	0.050
cellular response to hormone stimulus	GO:0032870	247	0.048
apoptotic process	GO:0006915	381	0.046
programmed cell death	GO:0012501	392	0.045
negative regulation of metabolic process	GO:0009892	331	0.045
positive regulation of molecular function	GO:0044093	230	0.043	Human
neuron death	GO:0070997	127	0.042
regulation of molecular function	GO:0065009	398	0.041	Human
response to external biotic stimulus	GO:0043207	221	0.041
amine metabolic process	GO:0009308	38	0.041
cellular response to lipid	GO:0071396	201	0.041
epithelium development	GO:0060429	96	0.041	Human
negative regulation of cell proliferation	GO:0008285	119	0.039
regulation of transcription dna templated	GO:0006355	374	0.039
neuron differentiation	GO:0030182	368	0.039	Rat
regulation of membrane potential	GO:0042391	110	0.038
cellular amine metabolic process	GO:0044106	38	0.038
rna metabolic process	GO:0016070	406	0.038
protein complex subunit organization	GO:0071822	302	0.037	Rat
cellular amino acid metabolic process	GO:0006520	107	0.036
regulation of cellular amine metabolic process	GO:0033238	8	0.036
response to peptide hormone	GO:0043434	278	0.036
central nervous system development	GO:0007417	311	0.035	Rat
positive regulation of nervous system development	GO:0051962	178	0.035
regulation of programmed cell death	GO:0043067	341	0.035
positive regulation of cell proliferation	GO:0008284	249	0.034	Human
brain development	GO:0007420	247	0.033	Rat
regulation of cellular amino acid metabolic process	GO:0006521	2	0.032
regulation of response to stress	GO:0080134	126	0.032
actin filament based process	GO:0030029	86	0.032
cellular component assembly	GO:0022607	360	0.032	Rat
positive regulation of gene expression	GO:0010628	244	0.032	Human
regulation of system process	GO:0044057	208	0.031
protein complex biogenesis	GO:0070271	263	0.031	Rat
cellular response to organonitrogen compound	GO:0071417	197	0.031
macromolecular complex assembly	GO:0065003	273	0.031	Rat
negative regulation of macromolecule metabolic process	GO:0010605	260	0.030
regulation of apoptotic process	GO:0042981	335	0.030
single organism organelle organization	GO:1902589	180	0.030
circulatory system process	GO:0003013	183	0.029
regulation of cellular protein metabolic process	GO:0032268	267	0.029
regulation of neurogenesis	GO:0050767	247	0.029	Rat
cation transport	GO:0006812	382	0.029
regulation of cell differentiation	GO:0045595	320	0.029	Rat
cellular response to stress	GO:0033554	269	0.029
cell morphogenesis	GO:0000902	142	0.029	Rat
cellular ion homeostasis	GO:0006873	184	0.028
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.028	Human
bmp signaling pathway	GO:0030509	4	0.028
response to insulin	GO:0032868	133	0.028
cellular response to oxygen containing compound	GO:1901701	386	0.028
response to peptide	GO:1901652	292	0.028
positive regulation of cell development	GO:0010720	176	0.028
cardiovascular system development	GO:0072358	134	0.028
positive regulation of cell differentiation	GO:0045597	217	0.027
oxoacid metabolic process	GO:0043436	290	0.027
carbohydrate derivative metabolic process	GO:1901135	346	0.027
regulation of hormone levels	GO:0010817	187	0.027
response to bacterium	GO:0009617	200	0.027
negative regulation of gene expression	GO:0010629	199	0.027
regulation of cell growth	GO:0001558	85	0.027	Rat
regulation of nervous system development	GO:0051960	264	0.026	Rat
organelle organization	GO:0006996	266	0.026
reproductive process	GO:0022414	372	0.025
action potential	GO:0001508	54	0.025
growth	GO:0040007	165	0.024	Rat
response to other organism	GO:0051707	220	0.024
positive regulation of signal transduction	GO:0009967	175	0.024	Human
negative regulation of multicellular organismal process	GO:0051241	203	0.024	Human
cell adhesion	GO:0007155	110	0.024	Rat
response to reactive oxygen species	GO:0000302	120	0.024
regulation of protein metabolic process	GO:0051246	289	0.024
regulation of organ formation	GO:0003156	2	0.023
homeostatic process	GO:0042592	331	0.023	Human
response to estrogen	GO:0043627	232	0.023
negative regulation of cell death	GO:0060548	229	0.023
cellular ketone metabolic process	GO:0042180	51	0.022
positive regulation of cellular amine metabolic process	GO:0033240	3	0.022
cellular component biogenesis	GO:0044085	368	0.022	Rat
regulation of rna biosynthetic process	GO:2001141	381	0.022
transcription dna templated	GO:0006351	377	0.022
regulation of catalytic activity	GO:0050790	304	0.022	Human
epithelial cell differentiation	GO:0030855	71	0.022	Human
organic acid metabolic process	GO:0006082	292	0.022
positive regulation of signaling	GO:0023056	270	0.022	Human
positive regulation of phosphate metabolic process	GO:0045937	262	0.022
positive regulation of rna metabolic process	GO:0051254	203	0.022
regulation of intracellular signal transduction	GO:1902531	218	0.022	Rat
positive regulation of cell communication	GO:0010647	271	0.021	Human
negative regulation of response to stimulus	GO:0048585	155	0.021
signal transduction by phosphorylation	GO:0023014	144	0.021
positive regulation of phosphorus metabolic process	GO:0010562	262	0.021
rna biosynthetic process	GO:0032774	380	0.020
sodium ion transmembrane transport	GO:0035725	67	0.020
vesicle mediated transport	GO:0016192	181	0.020
cation homeostasis	GO:0055080	195	0.020
localization of cell	GO:0051674	202	0.020
cellular chemical homeostasis	GO:0055082	247	0.019
negative regulation of apoptotic process	GO:0043066	181	0.019
regulation of multicellular organismal development	GO:2000026	376	0.019	Human Rat
regulation of signal transduction	GO:0009966	318	0.019	Human Rat
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.019
metal ion homeostasis	GO:0055065	186	0.019
immune system process	GO:0002376	204	0.019
heart process	GO:0003015	57	0.019
neuron projection development	GO:0031175	273	0.018	Rat
chemical homeostasis	GO:0048878	292	0.018
rhythmic process	GO:0048511	156	0.018
response to ketone	GO:1901654	182	0.018
negative regulation of cellular protein metabolic process	GO:0032269	106	0.018
regulation of cellular localization	GO:0060341	263	0.018	Human
regulation of blood circulation	GO:1903522	110	0.017
regulation of cell projection organization	GO:0031344	175	0.017	Rat
anion transmembrane transport	GO:0098656	77	0.017
neuronal action potential	GO:0019228	35	0.017
defense response	GO:0006952	194	0.017
hormone metabolic process	GO:0042445	69	0.017
heart morphogenesis	GO:0003007	3	0.017
regulation of canonical wnt signaling pathway	GO:0060828	4	0.017
regulation of organelle organization	GO:0033043	80	0.017
regulation of bmp signaling pathway	GO:0030510	2	0.017
macromolecular complex subunit organization	GO:0043933	339	0.017	Rat
cellular response to external stimulus	GO:0071496	118	0.017
response to molecule of bacterial origin	GO:0002237	194	0.017
head development	GO:0060322	247	0.016	Rat
hematopoietic progenitor cell differentiation	GO:0002244	2	0.016
response to acid chemical	GO:0001101	222	0.016
cellular cation homeostasis	GO:0030003	180	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.016
response to oxygen levels	GO:0070482	265	0.016
negative regulation of rna biosynthetic process	GO:1902679	118	0.016
regulation of cytokine production	GO:0001817	56	0.016	Human
ion homeostasis	GO:0050801	212	0.016
ovulation cycle	GO:0042698	67	0.016
positive regulation of cellular component organization	GO:0051130	200	0.016
positive regulation of cell motility	GO:2000147	97	0.016
mapk cascade	GO:0000165	140	0.016
response to biotic stimulus	GO:0009607	226	0.016
protein maturation	GO:0051604	68	0.016
anatomical structure morphogenesis	GO:0009653	298	0.015	Rat
regulation of immune system process	GO:0002682	123	0.015
protein complex assembly	GO:0006461	263	0.015	Rat
cellular response to abiotic stimulus	GO:0071214	85	0.015
negative regulation of transcription dna templated	GO:0045892	116	0.015
regulation of defense response	GO:0031347	68	0.015
positive regulation of phosphorylation	GO:0042327	177	0.015
regulation of kinase activity	GO:0043549	117	0.015
positive regulation of biosynthetic process	GO:0009891	319	0.015	Human
cellular component morphogenesis	GO:0032989	155	0.015	Rat
organic anion transport	GO:0015711	132	0.015
tube development	GO:0035295	89	0.015
gonad development	GO:0008406	104	0.015
positive regulation of cellular component movement	GO:0051272	102	0.014
regulation of heart contraction	GO:0008016	48	0.014
regulation of cell adhesion	GO:0030155	52	0.014
negative regulation of programmed cell death	GO:0043069	183	0.014
negative regulation of organic acid transport	GO:0032891	14	0.014
regulation of phosphorylation	GO:0042325	248	0.014
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.014
neurological system process	GO:0050877	219	0.014
transcription from rna polymerase ii promoter	GO:0006366	252	0.014
inflammatory response	GO:0006954	150	0.014
regulation of epithelial cell proliferation	GO:0050678	49	0.014	Human
cellular response to gonadotropin stimulus	GO:0071371	17	0.014
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.014
positive regulation of neurogenesis	GO:0050769	165	0.014
muscle system process	GO:0003012	115	0.014
g protein coupled receptor signaling pathway	GO:0007186	242	0.014
regulation of small gtpase mediated signal transduction	GO:0051056	48	0.013	Rat
regulation of cellular component organization	GO:0051128	368	0.013	Rat
cytoskeleton organization	GO:0007010	111	0.013
heart contraction	GO:0060047	57	0.013
eye morphogenesis	GO:0048592	4	0.013
respiratory system development	GO:0060541	45	0.013
cellular homeostasis	GO:0019725	252	0.013
cell type specific apoptotic process	GO:0097285	134	0.013
cellular response to lipopolysaccharide	GO:0071222	55	0.013
response to lipopolysaccharide	GO:0032496	191	0.013
cell projection organization	GO:0030030	302	0.013	Rat
regulation of leukocyte activation	GO:0002694	45	0.012
regulation of stem cell differentiation	GO:2000736	2	0.012
regulation of protein maturation	GO:1903317	50	0.012
regeneration	GO:0031099	163	0.012
cellular response to cytokine stimulus	GO:0071345	127	0.012
response to gonadotropin	GO:0034698	34	0.012
cell growth	GO:0016049	104	0.012	Rat
small gtpase mediated signal transduction	GO:0007264	36	0.012	Rat
negative regulation of cell communication	GO:0010648	158	0.012
wound healing	GO:0042060	122	0.012
biological adhesion	GO:0022610	110	0.012	Rat
positive regulation of immune system process	GO:0002684	90	0.012
proteolysis	GO:0006508	175	0.012
regulation of protein localization	GO:0032880	81	0.012	Rat
protein oligomerization	GO:0051259	191	0.012	Rat
regulation of phosphate metabolic process	GO:0019220	349	0.012
epithelial cell proliferation	GO:0050673	54	0.012	Human
regulation of neuron differentiation	GO:0045664	208	0.012	Rat
positive regulation of response to stimulus	GO:0048584	285	0.012	Human
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.012
positive regulation of stress activated mapk cascade	GO:0032874	17	0.012
myeloid leukocyte activation	GO:0002274	36	0.012
neural crest cell migration	GO:0001755	1	0.011
cell migration	GO:0016477	197	0.011
regulation of establishment of planar polarity	GO:0090175	2	0.011
lung development	GO:0030324	43	0.011
negative regulation of protein metabolic process	GO:0051248	114	0.011
protein heterooligomerization	GO:0051291	89	0.011	Rat
triglyceride homeostasis	GO:0070328	2	0.011
ovulation cycle process	GO:0022602	50	0.011
transmission of nerve impulse	GO:0019226	42	0.011
negative regulation of cytokine production	GO:0001818	16	0.011	Human
response to purine containing compound	GO:0014074	126	0.011
response to radiation	GO:0009314	137	0.011
cellular response to acid chemical	GO:0071229	75	0.011
cellular calcium ion homeostasis	GO:0006874	160	0.011
establishment of planar polarity	GO:0001736	1	0.011
transmembrane transport	GO:0055085	412	0.011
neural crest cell differentiation	GO:0014033	2	0.011
regulation of protein phosphorylation	GO:0001932	183	0.011
metal ion transport	GO:0030001	289	0.011
axon development	GO:0061564	96	0.011	Rat
respiratory tube development	GO:0030323	43	0.011
carbohydrate derivative biosynthetic process	GO:1901137	124	0.011
positive regulation of intracellular signal transduction	GO:1902533	138	0.011
regulation of mononuclear cell proliferation	GO:0032944	26	0.011
regulation of synaptic plasticity	GO:0048167	70	0.011
retina morphogenesis in camera type eye	GO:0060042	1	0.011
positive regulation of bone mineralization	GO:0030501	4	0.010
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.010
muscle cell proliferation	GO:0033002	84	0.010
positive regulation of protein metabolic process	GO:0051247	178	0.010
dna metabolic process	GO:0006259	96	0.010
regulation of cell development	GO:0060284	263	0.010	Rat
protein processing	GO:0016485	68	0.010
male gamete generation	GO:0048232	99	0.010
response to camp	GO:0051591	91	0.010
forebrain development	GO:0030900	98	0.010	Rat
regulation of body fluid levels	GO:0050878	90	0.010
glial cell differentiation	GO:0010001	65	0.010
negative regulation of protein processing	GO:0010955	47	0.010

Cdh3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability	Func Analog Org
sensory system disease	DOID:0050155	0.019
disease of anatomical entity	DOID:7	0.019	Human
eye and adnexa disease	DOID:1492	0.019
nervous system disease	DOID:863	0.019
musculoskeletal system disease	DOID:17	0.012

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