Rattus norvegicus

0 known processes

Sh2d1a

SH2 domain protein 1A

(Aliases: RGD1562408)

Sh2d1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transcription dna templatedGO:00063513770.171
regulation of rna biosynthetic processGO:20011413810.170
regulation of rna metabolic processGO:00512523910.159
immune system processGO:00023762040.159
Mouse
rna biosynthetic processGO:00327743800.146
rna metabolic processGO:00160704060.144
regulation of nucleic acid templated transcriptionGO:19035063800.136
regulation of transcription dna templatedGO:00063553740.131
negative regulation of nitrogen compound metabolic processGO:00511721610.108
negative regulation of rna metabolic processGO:00512531230.085
transcription from rna polymerase ii promoterGO:00063662520.085
negative regulation of cellular metabolic processGO:00313242810.082
positive regulation of multicellular organismal processGO:00512403870.079
chemical homeostasisGO:00488782920.077
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.075
negative regulation of biosynthetic processGO:00098901680.072
positive regulation of transportGO:00510502450.071
positive regulation of regulatory t cell differentiationGO:004559120.070
response to extracellular stimulusGO:00099913800.069
response to nutrient levelsGO:00316673700.067
regulation of cellular localizationGO:00603412630.067
response to nutrientGO:00075842480.065
negative regulation of metabolic processGO:00098923310.064
immune responseGO:00069551040.063
Mouse
positive regulation of biosynthetic processGO:00098913190.063
positive regulation of gene expressionGO:00106282440.062
cellular divalent inorganic cation homeostasisGO:00725031620.061
response to biotic stimulusGO:00096072260.060
positive regulation of nucleobase containing compound metabolic processGO:00459353190.058
divalent inorganic cation homeostasisGO:00725071650.056
response to woundingGO:00096112540.055
regulation of molecular functionGO:00650093980.055
metal ion homeostasisGO:00550651860.054
nucleic acid templated transcriptionGO:00976593790.054
positive regulation of rna biosynthetic processGO:19026801970.053
regulation of transcription from rna polymerase ii promoterGO:00063572340.052
cellular ion homeostasisGO:00068731840.052
response to growth factorGO:00708481890.052
cellular calcium ion homeostasisGO:00068741600.051
homeostatic processGO:00425923310.051
regulation of regulatory t cell differentiationGO:004558920.051
positive regulation of cellular biosynthetic processGO:00313282950.051
negative regulation of nucleic acid templated transcriptionGO:19035071170.049
negative regulation of cellular biosynthetic processGO:00313271610.048
negative regulation of macromolecule biosynthetic processGO:00105581480.047
positive regulation of macromolecule biosynthetic processGO:00105572470.046
secretionGO:00469033070.046
positive regulation of natural killer cell mediated cytotoxicityGO:004595420.046
Mouse
cellular chemical homeostasisGO:00550822470.044
regulation of neurogenesisGO:00507672470.044
cellular homeostasisGO:00197252520.044
response to cytokineGO:00340972150.043
regulation of alpha beta t cell activationGO:004663420.043
positive regulation of response to stimulusGO:00485842850.042
Mouse
cellular response to growth factor stimulusGO:00713631620.042
positive regulation of nitrogen compound metabolic processGO:00511733340.042
protein complex subunit organizationGO:00718223020.042
response to peptide hormoneGO:00434342780.041
cytosolic calcium ion homeostasisGO:00514801400.041
negative regulation of macromolecule metabolic processGO:00106052600.040
leukocyte differentiationGO:0002521300.040
response to external biotic stimulusGO:00432072210.039
regulation of secretionGO:00510462240.039
macromolecular complex subunit organizationGO:00439333390.039
behaviorGO:00076102050.038
positive regulation of cytosolic calcium ion concentrationGO:00072041220.037
ion homeostasisGO:00508012120.037
cell activationGO:0001775970.037
negative regulation of cell deathGO:00605482290.037
negative regulation of gene expressionGO:00106291990.036
cellular cation homeostasisGO:00300031800.035
cellular component movementGO:00069282480.035
regulation of immune response to tumor cellGO:000283730.035
negative regulation of rna biosynthetic processGO:19026791180.035
immune effector processGO:0002252530.035
Mouse
regulation of lymphocyte chemotaxisGO:190162310.034
negative regulation of nucleobase containing compound metabolic processGO:00459341530.034
regulation of protein modification processGO:00313991940.034
positive regulation of transcription dna templatedGO:00458931970.033
response to molecule of bacterial originGO:00022371940.033
leukocyte activationGO:0045321760.033
localization of cellGO:00516742020.033
agingGO:00075682410.033
nitrogen compound transportGO:00717052290.033
positive regulation of cell proliferationGO:00082842490.032
positive regulation of nucleic acid templated transcriptionGO:19035081970.032
organophosphate metabolic processGO:00196373700.032
inflammatory responseGO:00069541500.032
secretion by cellGO:00329402480.032
cellular component biogenesisGO:00440853680.031
regulation of signal transductionGO:00099663180.030
positive regulation of developmental processGO:00510942830.030
negative regulation of transcription dna templatedGO:00458921160.030
positive regulation of rna metabolic processGO:00512542030.030
positive regulation of cell developmentGO:00107201760.030
response to oxidative stressGO:00069791860.029
macromolecular complex assemblyGO:00650032730.029
cell projection organizationGO:00300303020.029
response to hydrogen peroxideGO:0042542890.029
regulation of cell differentiationGO:00455953200.029
cell motilityGO:00488702020.029
regulation of phosphorus metabolic processGO:00511743490.028
protein complex biogenesisGO:00702712630.028
positive regulation of cell migrationGO:0030335960.028
programmed cell deathGO:00125013920.028
cellular response to stressGO:00335542690.028
positive regulation of neurogenesisGO:00507691650.028
cellular component assemblyGO:00226073600.028
regulation of secretion by cellGO:19035302080.027
regulation of neuron deathGO:19012141150.027
single organism biosynthetic processGO:00447113420.027
nucleobase containing small molecule metabolic processGO:00550863160.027
protein phosphorylationGO:00064683450.026
positive regulation of protein modification processGO:00314011420.026
purine containing compound metabolic processGO:00725212530.026
regulation of locomotionGO:00400121480.026
calcium ion homeostasisGO:00550741620.026
regulation of t cell chemotaxisGO:001081910.025
positive regulation of phosphate metabolic processGO:00459372620.025
negative regulation of immune response to tumor cellGO:000283820.025
response to inorganic substanceGO:00100353770.025
regulation of programmed cell deathGO:00430673410.025
cellular metal ion homeostasisGO:00068751720.025
anatomical structure morphogenesisGO:00096532980.025
cellular response to external stimulusGO:00714961180.025
protein complex assemblyGO:00064612630.025
t cell receptor signaling pathwayGO:005085210.025
positive regulation of cellular component movementGO:00512721020.025
positive regulation of cell differentiationGO:00455972170.025
reproductive processGO:00224143720.025
response to acid chemicalGO:00011012220.024
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.024
amine metabolic processGO:0009308380.024
single organism intracellular transportGO:19025821660.024
neuron differentiationGO:00301823680.024
neuron projection developmentGO:00311752730.024
metal ion transportGO:00300012890.024
muscle system processGO:00030121150.024
regulation of cellular amine metabolic processGO:003323880.024
divalent inorganic cation transportGO:00725111340.024
intracellular transportGO:00469071850.024
cellular response to lipidGO:00713962010.024
alpha beta t cell differentiationGO:004663220.024
defense responseGO:00069521940.024
Mouse
carbohydrate derivative metabolic processGO:19011353460.023
response to tumor cellGO:000234740.023
positive regulation of phosphorus metabolic processGO:00105622620.023
positive regulation of alpha beta t cell activationGO:004663520.023
regulation of interferon gamma productionGO:003264930.023
intracellular signal transductionGO:00355563140.022
regulation of cell migrationGO:00303341280.022
regulation of cell developmentGO:00602842630.022
cell migrationGO:00164771970.022
cellular response to oxygen containing compoundGO:19017013860.021
regulation of apoptotic processGO:00429813350.021
cellular amino acid metabolic processGO:00065201070.021
positive regulation of b cell mediated immunityGO:000271420.021
positive regulation of necroptotic processGO:006054520.021
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.021
locomotionGO:00400112370.021
cytoskeleton organizationGO:00070101110.021
cellular response to endogenous stimulusGO:00714953770.021
positive regulation of immune responseGO:0050778420.021
Mouse
glycosyl compound metabolic processGO:19016571820.020
negative regulation of response to stimulusGO:00485851550.020
response to metal ionGO:00100382530.020
central nervous system developmentGO:00074173110.020
transmembrane transportGO:00550854120.020
single organism organelle organizationGO:19025891800.020
regulation of cytokine productionGO:0001817560.020
positive regulation of secretion by cellGO:19035321280.020
positive regulation of protein metabolic processGO:00512471780.020
immune system developmentGO:0002520410.020
cellular amine metabolic processGO:0044106380.020
biological adhesionGO:00226101100.019
regulation of cell motilityGO:20001451310.019
purine nucleoside metabolic processGO:00422781690.019
cardiovascular system developmentGO:00723581340.019
regulation of cellular component movementGO:00512701500.019
positive regulation of t cell migrationGO:200040610.019
response to reactive oxygen speciesGO:00003021200.019
peptidyl amino acid modificationGO:00181931260.019
actin cytoskeleton organizationGO:0030036730.019
cellular response to oxidative stressGO:0034599760.018
organelle organizationGO:00069962660.018
regulation of necroptotic processGO:006054420.018
reactive oxygen species biosynthetic processGO:190340980.018
regulation of catalytic activityGO:00507903040.018
cation homeostasisGO:00550801950.018
single organism reproductive processGO:00447022970.018
alpha beta t cell activationGO:004663130.018
response to other organismGO:00517072200.018
response to peptideGO:19016522920.018
hematopoietic or lymphoid organ developmentGO:0048534360.018
regulation of ion transportGO:00432692450.018
wound healingGO:00420601220.018
positive regulation of molecular functionGO:00440932300.018
regulation of multicellular organismal developmentGO:20000263760.018
cellular response to hormone stimulusGO:00328702470.018
negative regulation of transportGO:00510511360.018
response to estrogenGO:00436272320.018
regulation of cellular ketone metabolic processGO:0010565270.018
hormone transportGO:00099141210.018
immunoglobulin mediated immune responseGO:001606440.018
regulation of cellular component organizationGO:00511283680.018
regulation of hormone levelsGO:00108171870.018
response to bacteriumGO:00096172000.018
circulatory system processGO:00030131830.017
purine ribonucleotide metabolic processGO:00091502270.017
response to ethanolGO:00454711620.017
nucleoside phosphate metabolic processGO:00067532830.017
negative regulation of response to tumor cellGO:000283520.017
circulatory system developmentGO:00723591340.017
cellular response to vitamin kGO:007130710.017
immune response to tumor cellGO:000241830.017
positive regulation of cellular protein metabolic processGO:00322701670.017
positive regulation of natural killer cell mediated immunityGO:000271720.017
Mouse
positive regulation of protein phosphorylationGO:00019341350.017
multi organism reproductive processGO:00447032620.016
purine ribonucleoside triphosphate metabolic processGO:00092051400.016
cellular response to extracellular stimulusGO:0031668730.016
regulation of cell proliferationGO:00421273590.016
negative regulation of natural killer cell mediated immune response to tumor cellGO:000285610.016
regulation of protein metabolic processGO:00512462890.016
apoptotic processGO:00069153810.016
antigen receptor mediated signaling pathwayGO:005085110.016
regulation of intracellular transportGO:0032386650.016
regulation of cellular protein metabolic processGO:00322682670.016
regulation of cellular amino acid metabolic processGO:000652120.016
positive regulation of nervous system developmentGO:00519621780.016
regulation of defense responseGO:0031347680.016
Mouse
negative regulation of immune system processGO:0002683390.016
regulation of cd4 positive alpha beta t cell activationGO:200051410.016
cytoplasmic transportGO:00164821150.016
cellular response to nitrogen compoundGO:19016992100.016
cd4 positive alpha beta t cell activationGO:003571010.016
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.016
positive regulation of defense responseGO:0031349370.016
Mouse
regulation of reactive oxygen species biosynthetic processGO:190342650.015
pseudopodium assemblyGO:003126930.015
cation transportGO:00068123820.015
signal releaseGO:00230611450.015
b cell differentiationGO:003018320.015
g protein coupled receptor signaling pathwayGO:00071862420.015
positive regulation of immunoglobulin mediated immune responseGO:000289120.015
cytokine mediated signaling pathwayGO:0019221430.015
cell adhesionGO:00071551100.015
nucleoside metabolic processGO:00091161790.015
regulation of intracellular signal transductionGO:19025312180.015
ribonucleotide metabolic processGO:00092592310.015
regulation of calcium ion transportGO:0051924770.015
multicellular organismal reproductive processGO:00486092330.015
regulation of immune system processGO:00026821230.015
Mouse
regulation of natural killer cell mediated immune response to tumor cellGO:000285510.015
lymphocyte chemotaxisGO:004824730.015
ribonucleoside metabolic processGO:00091191740.015
reactive nitrogen species metabolic processGO:200105710.015
regulation of lymphocyte migrationGO:200040110.015
response to amino acidGO:0043200750.015
regulation of response to stressGO:00801341260.015
Mouse
hemopoiesisGO:0030097340.015
positive regulation of neuron differentiationGO:00456661260.015
response to oxygen levelsGO:00704822650.015
response to corticosteroidGO:00319602350.015
ribose phosphate metabolic processGO:00196932350.015
ras protein signal transductionGO:0007265290.015
hormone secretionGO:00468791150.015
regulation of membrane potentialGO:00423911100.015
negative regulation of homeostatic processGO:0032845470.015
lipid metabolic processGO:00066292830.015
neuron deathGO:00709971270.015
regulation of metal ion transportGO:00109591180.014
nucleotide metabolic processGO:00091172790.014
positive regulation of protein kinase activityGO:0045860730.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
regulation of nervous system developmentGO:00519602640.014
natural killer cell mediated immune response to tumor cellGO:000242310.014
negative regulation of cell communicationGO:00106481580.014
ribonucleoside triphosphate metabolic processGO:00091991410.014
divalent metal ion transportGO:00708381320.014
response to lipopolysaccharideGO:00324961910.014
negative regulation of programmed cell deathGO:00430691830.014
cell cell signalingGO:00072673350.014
Human
pseudopodium organizationGO:003126830.014
regulation of hormone secretionGO:00468831060.014
cellular response to alcoholGO:0097306870.014
carbohydrate derivative catabolic processGO:19011361470.014
lymphocyte activationGO:0046649430.014
cellular response to organic cyclic compoundGO:00714072020.014
regenerationGO:00310991630.014
response to decreased oxygen levelsGO:00362932370.014
positive regulation of cell deathGO:00109421840.014
sequestering of calcium ionGO:005120880.014
regulation of response to external stimulusGO:00321011060.014
nucleobase containing compound catabolic processGO:00346551520.014
cellular response to ketoneGO:1901655510.014
purine containing compound catabolic processGO:00725231380.013
regulation of homeostatic processGO:00328441010.013
negative regulation of signalingGO:00230571570.013
growthGO:00400071650.013
regulation of system processGO:00440572080.013
sequestering of metal ionGO:005123890.013
negative regulation of neuron deathGO:1901215690.013
cellular nitrogen compound catabolic processGO:00442701630.013
organic acid metabolic processGO:00060822920.013
reactive oxygen species metabolic processGO:0072593370.013
small gtpase mediated signal transductionGO:0007264360.013
cation transmembrane transportGO:00986552630.013
cellular response to lipopolysaccharideGO:0071222550.013
response to tumor necrosis factorGO:0034612560.013
necroptotic processGO:007026620.013
cellular response to cytokine stimulusGO:00713451270.013
t cell activationGO:0042110290.012
aromatic compound catabolic processGO:00194391680.012
negative regulation of innate immune responseGO:004582440.012
sexual reproductionGO:00199531480.012
regulation of fc receptor mediated stimulatory signaling pathwayGO:006036830.012
catabolic processGO:00090563510.012
purine ribonucleoside metabolic processGO:00461281680.012
positive regulation of endothelial cell migrationGO:001059540.012
proteolysisGO:00065081750.012
cellular ketone metabolic processGO:0042180510.012
regulation of catabolic processGO:00098941130.012
positive regulation of lymphocyte activationGO:0051251250.012
negative regulation of cell differentiationGO:0045596990.012
acute inflammatory responseGO:0002526580.012
viral transcriptionGO:001908320.012
regulation of mesenchymal cell proliferationGO:001046440.012
oxoacid metabolic processGO:00434362900.012
regulation of reactive oxygen species metabolic processGO:2000377260.012
regulation of neuron projection developmentGO:00109751610.012
organic cyclic compound catabolic processGO:19013611750.012
regulation of response to woundingGO:1903034690.012
tissue developmentGO:00098882520.012
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285910.012
positive regulation of cellular amine metabolic processGO:003324030.012
enzyme linked receptor protein signaling pathwayGO:00071671160.012
response to carbohydrateGO:00097431830.012
salivary gland morphogenesisGO:000743510.011
lymphocyte migrationGO:007267630.011
regulation of immunoglobulin mediated immune responseGO:000288920.011
cellular response to reactive oxygen speciesGO:0034614550.011
regulation of protein phosphorylationGO:00019321830.011
positive regulation of lipid kinase activityGO:009021820.011
t cell migrationGO:007267820.011
heterocycle catabolic processGO:00467001670.011
negative regulation of natural killer cell mediated immunityGO:000271640.011
regulation of phosphate metabolic processGO:00192203490.011
single organism catabolic processGO:00447122830.011
cytokine productionGO:0001816610.011
cell morphogenesis involved in differentiationGO:00009041190.011
interferon gamma productionGO:003260930.011
neuron developmentGO:00486662860.011
positive regulation of cellular component organizationGO:00511302000.011
regulation of interleukin 1 alpha biosynthetic processGO:005072110.011
reproductionGO:00000032450.011
regulation of peptide secretionGO:0002791820.011
positive regulation of cell projection organizationGO:00313461110.011
regulation of neuron differentiationGO:00456642080.011
glycosyl compound catabolic processGO:19016581260.011
response to vitaminGO:00332731310.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
negative regulation of developmental processGO:00510931250.011
carboxylic acid metabolic processGO:00197522890.011
negative regulation of molecular functionGO:00440921330.011
regulation of lipid metabolic processGO:0019216680.011
protein oligomerizationGO:00512591910.011
purine nucleotide metabolic processGO:00061632290.011
positive regulation of locomotionGO:00400171020.011
programmed necrotic cell deathGO:009730020.011
cellular response to acid chemicalGO:0071229750.011
cellular macromolecular complex assemblyGO:0034622580.011
negative regulation of catalytic activityGO:00430861030.011
positive regulation of signal transductionGO:00099671750.011
cellular component morphogenesisGO:00329891550.011
response to mechanical stimulusGO:00096121340.010
positive regulation of mesenchymal cell proliferationGO:000205340.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.010
macromolecule localizationGO:00330362520.010
actin filament based processGO:0030029860.010
calcium ion transport into cytosolGO:0060402380.010
nucleoside triphosphate metabolic processGO:00091411440.010
nucleotide catabolic processGO:00091661390.010
purine ribonucleotide catabolic processGO:00091541360.010
response to hexoseGO:00097461440.010
response to estradiolGO:00323551640.010
inorganic ion transmembrane transportGO:00986602290.010
positive regulation of cell motilityGO:2000147970.010
myeloid leukocyte activationGO:0002274360.010
cellular response to organonitrogen compoundGO:00714171970.010
response to hypoxiaGO:00016662310.010

Sh2d1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.011
musculoskeletal system diseaseDOID:1700.011