Rattus norvegicus

0 known processes

Irs3

insulin receptor substrate 3

Irs3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of rna metabolic processGO:00512523910.364
lipid metabolic processGO:00066292830.271
Rat
cellular lipid metabolic processGO:00442552080.252
Rat
regulation of transcription dna templatedGO:00063553740.245
cellular response to acid chemicalGO:0071229750.240
anatomical structure morphogenesisGO:00096532980.239
regulation of rna biosynthetic processGO:20011413810.233
positive regulation of rna metabolic processGO:00512542030.229
rna metabolic processGO:00160704060.213
cellular response to hormone stimulusGO:00328702470.201
Rat
cellular response to oxygen containing compoundGO:19017013860.197
Rat
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.184
negative regulation of cellular metabolic processGO:00313242810.174
regulation of cellular component organizationGO:00511283680.173
cell type specific apoptotic processGO:00972851340.170
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.167
negative regulation of metabolic processGO:00098923310.160
transcription from rna polymerase ii promoterGO:00063662520.142
positive regulation of transcription dna templatedGO:00458931970.138
central nervous system developmentGO:00074173110.138
enzyme linked receptor protein signaling pathwayGO:00071671160.135
Rat
oxidation reduction processGO:00551143040.135
response to growth factorGO:00708481890.130
organophosphate metabolic processGO:00196373700.128
Rat
programmed cell deathGO:00125013920.127
negative regulation of macromolecule metabolic processGO:00106052600.126
cellular response to lipidGO:00713962010.123
positive regulation of multicellular organismal processGO:00512403870.122
transcription dna templatedGO:00063513770.118
response to other organismGO:00517072200.117
positive regulation of rna biosynthetic processGO:19026801970.117
negative regulation of cellular biosynthetic processGO:00313271610.116
single organism biosynthetic processGO:00447113420.114
rna biosynthetic processGO:00327743800.114
negative regulation of transcription dna templatedGO:00458921160.113
monocarboxylic acid metabolic processGO:00327871520.112
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.106
apoptotic processGO:00069153810.104
negative regulation of biosynthetic processGO:00098901680.102
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.100
Rat
response to carbohydrateGO:00097431830.098
response to peptide hormoneGO:00434342780.098
Rat
response to peptideGO:19016522920.098
Rat
regulation of nervous system developmentGO:00519602640.093
positive regulation of macromolecule biosynthetic processGO:00105572470.093
regulation of multicellular organismal developmentGO:20000263760.093
response to hexoseGO:00097461440.092
organonitrogen compound biosynthetic processGO:19015661670.091
cellular component morphogenesisGO:00329891550.091
negative regulation of rna metabolic processGO:00512531230.089
regulation of cell motilityGO:20001451310.086
positive regulation of gene expressionGO:00106282440.084
nucleic acid templated transcriptionGO:00976593790.081
positive regulation of cellular biosynthetic processGO:00313282950.077
gland developmentGO:00487321550.077
negative regulation of nucleic acid templated transcriptionGO:19035071170.077
response to inorganic substanceGO:00100353770.076
positive regulation of nitrogen compound metabolic processGO:00511733340.075
positive regulation of nucleic acid templated transcriptionGO:19035081970.074
positive regulation of developmental processGO:00510942830.073
b cell differentiationGO:003018320.072
regulation of nucleic acid templated transcriptionGO:19035063800.072
oxoacid metabolic processGO:00434362900.072
regulation of signal transductionGO:00099663180.071
Rat
chemical homeostasisGO:00488782920.069
carbohydrate metabolic processGO:00059751300.068
negative regulation of rna biosynthetic processGO:19026791180.068
lipid biosynthetic processGO:00086101280.066
positive regulation of biosynthetic processGO:00098913190.066
intracellular signal transductionGO:00355563140.062
negative regulation of macromolecule biosynthetic processGO:00105581480.061
organ morphogenesisGO:0009887750.061
hexose metabolic processGO:0019318580.060
response to extracellular stimulusGO:00099913800.060
regulation of transcription from rna polymerase ii promoterGO:00063572340.059
kidney morphogenesisGO:0060993130.059
tissue developmentGO:00098882520.059
negative regulation of gene expressionGO:00106291990.058
cellular response to insulin stimulusGO:0032869810.058
Rat
regulation of anatomical structure morphogenesisGO:00226031410.058
response to insulinGO:00328681330.056
Rat
cell migrationGO:00164771970.056
positive regulation of nucleobase containing compound metabolic processGO:00459353190.055
cell projection organizationGO:00300303020.055
homeostatic processGO:00425923310.055
response to corticosteroidGO:00319602350.054
regulation of cell differentiationGO:00455953200.054
cellular response to organonitrogen compoundGO:00714171970.053
Rat
cellular response to endogenous stimulusGO:00714953770.053
Rat
positive regulation of transportGO:00510502450.052
Rat
regulation of cell developmentGO:00602842630.052
monosaccharide metabolic processGO:0005996610.051
cell substrate adhesionGO:0031589290.048
negative regulation of nucleobase containing compound metabolic processGO:00459341530.048
single organism reproductive processGO:00447022970.048
cellular component movementGO:00069282480.048
glucose metabolic processGO:0006006520.047
regulation of locomotionGO:00400121480.047
multi organism reproductive processGO:00447032620.047
epibolyGO:009050420.046
single organism organelle organizationGO:19025891800.045
cellular response to peptideGO:19016531330.045
Rat
regenerationGO:00310991630.045
carbohydrate homeostasisGO:0033500750.045
nucleoside phosphate metabolic processGO:00067532830.044
locomotionGO:00400112370.044
protein phosphorylationGO:00064683450.043
positive regulation of cell differentiationGO:00455972170.042
head developmentGO:00603222470.041
regulation of molecular functionGO:00650093980.041
Rat
reproductionGO:00000032450.041
multicellular organism reproductionGO:00325042330.041
hepaticobiliary system developmentGO:0061008900.041
cellular response to peptide hormone stimulusGO:00713751200.039
Rat
forebrain developmentGO:0030900980.038
neuron differentiationGO:00301823680.038
negative regulation of kidney developmentGO:009018520.037
positive regulation of signalingGO:00230562700.037
Rat
catabolic processGO:00090563510.037
muscle cell proliferationGO:0033002840.036
regulation of lipid metabolic processGO:0019216680.035
Rat
urogenital system developmentGO:0001655780.034
cardiovascular system developmentGO:00723581340.034
positive regulation of signal transductionGO:00099671750.034
Rat
gamete generationGO:00072761240.034
multicellular organismal reproductive processGO:00486092330.033
response to oxygen levelsGO:00704822650.033
cell morphogenesisGO:00009021420.033
negative regulation of programmed cell deathGO:00430691830.032
multi multicellular organism processGO:00447061380.032
regulation of immune system processGO:00026821230.032
regulation of cell migrationGO:00303341280.031
cell motilityGO:00488702020.031
regulation of phosphate metabolic processGO:00192203490.031
Rat
cellular homeostasisGO:00197252520.031
protein homooligomerizationGO:0051260910.031
positive regulation of neuron differentiationGO:00456661260.031
tube developmentGO:0035295890.030
fatty acid metabolic processGO:0006631990.030
nucleobase containing small molecule metabolic processGO:00550863160.030
muscle structure developmentGO:0061061870.030
regulation of cell proliferationGO:00421273590.030
negative regulation of nitrogen compound metabolic processGO:00511721610.029
negative regulation of epithelial cell proliferationGO:0050680160.029
epiboly involved in wound healingGO:009050520.029
response to monosaccharideGO:00342841590.029
response to glucocorticoidGO:00513842230.029
nucleoside monophosphate metabolic processGO:0009123930.028
signal transduction by phosphorylationGO:00230141440.028
regulation of neurogenesisGO:00507672470.028
neuron developmentGO:00486662860.028
positive regulation of cellular protein metabolic processGO:00322701670.028
ribonucleotide metabolic processGO:00092592310.027
wound healing spreading of epidermal cellsGO:003531320.027
positive regulation of mesenchymal cell proliferationGO:000205340.027
proteolysisGO:00065081750.027
cellular component biogenesisGO:00440853680.027
Rat
negative regulation of cell deathGO:00605482290.027
epithelium developmentGO:0060429960.026
regulation of protein metabolic processGO:00512462890.026
glucose homeostasisGO:0042593750.026
localization of cellGO:00516742020.026
positive regulation of nervous system developmentGO:00519621780.026
hormone mediated signaling pathwayGO:0009755230.026
response to external biotic stimulusGO:00432072210.025
anatomical structure formation involved in morphogenesisGO:0048646830.025
glycerolipid metabolic processGO:0046486670.025
Rat
positive regulation of molecular functionGO:00440932300.025
Rat
insulin receptor signaling pathwayGO:0008286240.025
Rat
regulation of neuron differentiationGO:00456642080.025
cellular response to growth factor stimulusGO:00713631620.025
epithelial cell proliferationGO:0050673540.025
response to acid chemicalGO:00011012220.024
regulation of apoptotic processGO:00429813350.024
osteoblast differentiationGO:0001649260.024
response to nutrient levelsGO:00316673700.024
regulation of cell projection organizationGO:00313441750.024
positive regulation of neurogenesisGO:00507691650.024
defense responseGO:00069521940.024
nuclear transportGO:0051169490.024
response to woundingGO:00096112540.024
regulation of endothelial cell apoptotic processGO:200035130.024
bmp signaling pathwayGO:003050940.024
carboxylic acid metabolic processGO:00197522890.023
acute inflammatory responseGO:0002526580.023
purine nucleotide metabolic processGO:00061632290.023
kidney developmentGO:0001822670.023
dephosphorylationGO:0016311980.023
regulation of cellular protein metabolic processGO:00322682670.023
regulation of lipid kinase activityGO:004355070.022
Rat
motor neuron axon guidanceGO:000804510.022
response to biotic stimulusGO:00096072260.022
triglyceride metabolic processGO:0006641210.022
brain developmentGO:00074202470.022
embryonic skeletal system developmentGO:004870630.022
response to glucoseGO:00097491360.022
organ regenerationGO:00311001010.022
response to cytokineGO:00340972150.022
organic acid metabolic processGO:00060822920.021
morphogenesis of an epitheliumGO:0002009200.021
reactive oxygen species metabolic processGO:0072593370.021
positive regulation of cellular component organizationGO:00511302000.021
erythrocyte differentiationGO:003021810.021
negative regulation of apoptotic processGO:00430661810.021
response to purine containing compoundGO:00140741260.021
Rat
wound healing spreading of cellsGO:004431920.021
regulation of metanephros developmentGO:007221540.021
regulation of homotypic cell cell adhesionGO:003411040.021
regulation of canonical wnt signaling pathwayGO:006082840.021
regulation of neuron projection developmentGO:00109751610.021
regulation of phosphorylationGO:00423252480.021
Rat
carbohydrate derivative biosynthetic processGO:19011371240.021
nucleotide metabolic processGO:00091172790.021
purine containing compound metabolic processGO:00725212530.021
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.021
cellular glucan metabolic processGO:0006073230.020
positive regulation of tumor necrosis factor productionGO:003276080.020
nucleoside triphosphate metabolic processGO:00091411440.020
organophosphate biosynthetic processGO:00904071430.020
negative regulation of metanephros developmentGO:007221720.020
regulation of cellular component movementGO:00512701500.020
response to dexamethasoneGO:0071548490.020
positive regulation of lipid metabolic processGO:0045834330.020
Rat
regulation of body fluid levelsGO:0050878900.020
positive regulation of cellular component movementGO:00512721020.020
negative regulation of signalingGO:00230571570.019
Rat
monocarboxylic acid catabolic processGO:0072329280.019
organelle organizationGO:00069962660.019
protein oligomerizationGO:00512591910.019
Rat
peptide transportGO:0015833970.019
Rat
regulation of cell growthGO:0001558850.019
positive regulation of phosphorylationGO:00423271770.019
Rat
negative regulation of cell differentiationGO:0045596990.019
blood circulationGO:00080151830.019
peptide hormone secretionGO:0030072840.019
Rat
smooth muscle cell proliferationGO:0048659770.018
carbohydrate derivative metabolic processGO:19011353460.018
hormone transportGO:00099141210.018
Rat
neuron projection developmentGO:00311752730.018
regulation of mesenchymal cell proliferationGO:001046440.018
mesoderm developmentGO:000749820.018
protein complex assemblyGO:00064612630.018
Rat
response to hypoxiaGO:00016662310.018
regulation of system processGO:00440572080.018
telencephalon developmentGO:0021537620.018
regulation of nephron tubule epithelial cell differentiationGO:007218210.018
positive regulation of humoral immune responseGO:000292220.018
mesenchymal cell proliferationGO:001046340.017
agingGO:00075682410.017
salivary gland developmentGO:000743130.017
positive regulation of phosphorus metabolic processGO:00105622620.017
Rat
response to ketoneGO:19016541820.017
purine containing compound biosynthetic processGO:0072522850.017
nitrogen compound transportGO:00717052290.017
Rat
positive regulation of cell developmentGO:00107201760.017
spermatogenesisGO:0007283990.016
ribose phosphate metabolic processGO:00196932350.016
macromolecular complex subunit organizationGO:00439333390.016
Rat
steroid metabolic processGO:0008202730.016
multicellular organism growthGO:003526410.016
response to molecule of bacterial originGO:00022371940.016
cellular response to hexose stimulusGO:0071331650.016
protein targeting to nucleusGO:0044744350.016
developmental inductionGO:003112820.016
endothelial cell apoptotic processGO:007257730.016
cellular response to abiotic stimulusGO:0071214850.016
anterior posterior pattern specificationGO:000995210.016
heart morphogenesisGO:000300730.016
tissue morphogenesisGO:0048729220.016
gastrulationGO:000736920.016
nephron developmentGO:0072006220.016
myelinationGO:0042552390.015
regulation of dna metabolic processGO:0051052600.015
regulation of phosphatidylinositol 3 kinase activityGO:004355170.015
Rat
inner ear morphogenesisGO:004247210.015
transmission of nerve impulseGO:0019226420.015
morphogenesis of an epithelial sheetGO:000201120.015
cholesterol homeostasisGO:004263230.015
positive regulation of immune system processGO:0002684900.015
negative regulation of protein metabolic processGO:00512481140.015
embryo developmentGO:0009790490.015
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000333920.015
neurological system processGO:00508772190.015
cellular ion homeostasisGO:00068731840.015
regulation of growthGO:00400081050.015
cellular response to nitrogen compoundGO:19016992100.015
Rat
skeletal muscle satellite cell proliferationGO:001484110.015
negative regulation of cellular protein metabolic processGO:00322691060.015
cytoskeleton organizationGO:00070101110.015
regulation of proteolysisGO:0030162660.015
regulation of smooth muscle cell proliferationGO:0048660750.015
b cell mediated immunityGO:001972440.015
renal system developmentGO:0072001670.015
positive regulation of interleukin 1 alpha productionGO:003273010.014
behaviorGO:00076102050.014
sexual reproductionGO:00199531480.014
positive regulation of protein metabolic processGO:00512471780.014
epithelial cell differentiationGO:0030855710.014
t cell homeostasisGO:004302920.014
regulation of catalytic activityGO:00507903040.014
Rat
generation of precursor metabolites and energyGO:0006091620.014
glycogen metabolic processGO:0005977230.014
cellular chemical homeostasisGO:00550822470.014
myeloid cell differentiationGO:0030099220.014
divalent inorganic cation homeostasisGO:00725071650.014
regulation of phagocytosis engulfmentGO:006009940.014
response to decreased oxygen levelsGO:00362932370.014
multicellular organismal water homeostasisGO:005089140.014
metanephric comma shaped body morphogenesisGO:007227820.014
neural crest cell developmentGO:001403220.014
liver developmentGO:0001889900.014
regulation of reactive oxygen species metabolic processGO:2000377260.014
single organism carbohydrate metabolic processGO:00447231180.014
dna metabolic processGO:0006259960.014
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.013
jak stat cascadeGO:0007259260.013
metanephric s shaped body morphogenesisGO:007228420.013
dicarboxylic acid metabolic processGO:0043648420.013
immune system processGO:00023762040.013
regulation of programmed cell deathGO:00430673410.013
protein processingGO:0016485680.013
protein complex biogenesisGO:00702712630.013
Rat
purine nucleotide biosynthetic processGO:0006164830.013
antigen processing and presentationGO:001988220.013
cellular polysaccharide metabolic processGO:0044264230.013
phosphatidylinositol 3 kinase signalingGO:0014065140.013
fatty acid catabolic processGO:0009062260.013
striated muscle cell differentiationGO:0051146390.013
circulatory system processGO:00030131830.013
response to genisteinGO:003359540.013
protein maturationGO:0051604680.013
negative regulation of cellular component organizationGO:0051129830.013
regulation of skeletal muscle tissue regenerationGO:004341620.013
regulation of muscle system processGO:0090257790.012
cell adhesionGO:00071551100.012
positive regulation of response to stimulusGO:00485842850.012
Rat
metal ion homeostasisGO:00550651860.012
cellular component assemblyGO:00226073600.012
Rat
regulation of proteasomal protein catabolic processGO:006113640.012
establishment of protein localization to organelleGO:0072594440.012
regulation of cell morphogenesisGO:0022604770.012
cellular glucose homeostasisGO:0001678660.012
positive regulation of glutamate secretionGO:001404980.012
regulation of cytokine productionGO:0001817560.012
developmental process involved in reproductionGO:00030061590.012
cellular response to cytokine stimulusGO:00713451270.012
substrate dependent cell migrationGO:000692910.012
regulation of ion transportGO:00432692450.012
immunoglobulin mediated immune responseGO:001606440.012
peptidyl tyrosine modificationGO:0018212720.012
negative regulation of multicellular organismal processGO:00512412030.012
immune responseGO:00069551040.012
cellular response to carbohydrate stimulusGO:0071322720.012
negative regulation of transportGO:00510511360.012
Rat
regulation of hydrolase activityGO:00513361430.012
anion transportGO:00068201780.012
negative regulation of developmental processGO:00510931250.012
reproductive processGO:00224143720.012
feeding behaviorGO:0007631530.012
sodium ion homeostasisGO:0055078230.012
adenohypophysis developmentGO:002198420.012
hormone biosynthetic processGO:0042446250.012
amine metabolic processGO:0009308380.012
regulation of cellular amino acid metabolic processGO:000652120.012
respiratory system developmentGO:0060541450.012
negative regulation of cell matrix adhesionGO:000195330.012
neuron projection morphogenesisGO:00488121220.012
divalent metal ion transportGO:00708381320.012
response to amino acidGO:0043200750.012
cellular response to monosaccharide stimulusGO:0071326670.012
female pregnancyGO:00075651220.011
positive regulation of cellular amine metabolic processGO:003324030.011
monocarboxylic acid biosynthetic processGO:0072330480.011
tube morphogenesisGO:0035239230.011
energy derivation by oxidation of organic compoundsGO:0015980460.011
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555130.011
regulation of cellular component biogenesisGO:0044087860.011
cation transportGO:00068123820.011
muscle cell differentiationGO:0042692520.011
muscle cell developmentGO:0055001260.011
olfactory bulb interneuron differentiationGO:002188910.011
regulation of cellular localizationGO:00603412630.011
Rat
regulation of phosphorus metabolic processGO:00511743490.011
Rat
glycosyl compound metabolic processGO:19016571820.011
chromosome segregationGO:000705920.011
negative regulation of protein maturationGO:1903318470.011
erythrocyte homeostasisGO:003410120.011
vascular process in circulatory systemGO:0003018960.011
chemotaxisGO:0006935660.011
positive regulation of potassium ion transmembrane transportGO:190138140.011
response to nutrientGO:00075842480.011
response to testosteroneGO:0033574550.011
cell adhesion molecule productionGO:006035210.011
cytokine biosynthetic processGO:004208930.011
regulation of anatomical structure sizeGO:00900661350.011
blood vessel developmentGO:0001568690.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
male gamete generationGO:0048232990.011
vasculature developmentGO:0001944700.010
reactive oxygen species biosynthetic processGO:190340980.010
cellular protein localizationGO:00346131220.010
regulation of response to stressGO:00801341260.010
regulation of epithelial cell differentiation involved in kidney developmentGO:200069610.010
negative regulation of cell communicationGO:00106481580.010
Rat
ribose phosphate biosynthetic processGO:0046390870.010
positive regulation of lamellipodium assemblyGO:001059240.010
lipid storageGO:001991510.010
regulation of tumor necrosis factor productionGO:0032680130.010
lymphoid progenitor cell differentiationGO:000232020.010
cellular response to dna damage stimulusGO:0006974190.010
reproductive structure developmentGO:00486081280.010

Irs3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
primary ciliary dyskinesiaDOID:956200.043
respiratory system diseaseDOID:157900.039
disease of anatomical entityDOID:700.039
lower respiratory tract diseaseDOID:005016100.039
nervous system diseaseDOID:86300.037
disease of metabolismDOID:001466700.019
nutrition diseaseDOID:37400.018
acquired metabolic diseaseDOID:006015800.018
urinary system diseaseDOID:1800.018
overnutritionDOID:65400.014
obesityDOID:997000.014
long qt syndromeDOID:284300.011