IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Ddx3x

DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked

RGD: 1564771
Entrez: 317335
UniProtKB: D4ADE8

Process Predictions
Disease Predictions

Ddx3x biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
reproductive process	GO:0022414	372	0.232
response to reactive oxygen species	GO:0000302	120	0.135
phototransduction visible light	GO:0007603	2	0.117
glutamate receptor signaling pathway	GO:0007215	43	0.096
reproduction	GO:0000003	245	0.094
monovalent inorganic cation transport	GO:0015672	172	0.094
activation of phospholipase d activity	GO:0031584	2	0.082
response to nutrient levels	GO:0031667	370	0.082
regulation of cell proliferation	GO:0042127	359	0.072
developmental process involved in reproduction	GO:0003006	159	0.067
reproductive structure development	GO:0048608	128	0.066
sodium ion transport	GO:0006814	82	0.060
response to extracellular stimulus	GO:0009991	380	0.050
reproductive system development	GO:0061458	128	0.047
regulation of cell differentiation	GO:0045595	320	0.044
organelle organization	GO:0006996	266	0.043
gonad development	GO:0008406	104	0.041
development of primary sexual characteristics	GO:0045137	107	0.039
sexual reproduction	GO:0019953	148	0.039
multicellular organismal reproductive process	GO:0048609	233	0.039
adenosine receptor signaling pathway	GO:0001973	7	0.038
embryonic axis specification	GO:0000578	1	0.038
detection of chemical stimulus involved in sensory perception of bitter taste	GO:0001580	4	0.037
cellular metal ion homeostasis	GO:0006875	172	0.037
g protein coupled purinergic receptor signaling pathway	GO:0035588	8	0.035
amine metabolic process	GO:0009308	38	0.035
negative regulation of ion transport	GO:0043271	51	0.034
chemotaxis	GO:0006935	66	0.033
cell projection organization	GO:0030030	302	0.033
multi organism reproductive process	GO:0044703	262	0.032
cell cycle	GO:0007049	101	0.031
regulation of metal ion transport	GO:0010959	118	0.031
positive regulation of cell communication	GO:0010647	271	0.030
metal ion transport	GO:0030001	289	0.030
neuron projection development	GO:0031175	273	0.030
negative regulation of cellular metabolic process	GO:0031324	281	0.030
potassium ion transport	GO:0006813	97	0.029
single organism reproductive process	GO:0044702	297	0.029
translation	GO:0006412	35	0.028
neuron development	GO:0048666	286	0.028
multicellular organism growth	GO:0035264	1	0.028
sex differentiation	GO:0007548	113	0.028
negative regulation of cell communication	GO:0010648	158	0.027
cellular amine metabolic process	GO:0044106	38	0.026
multicellular organism reproduction	GO:0032504	233	0.025
transmembrane transport	GO:0055085	412	0.025
organic acid metabolic process	GO:0006082	292	0.025
regulation of cellular protein metabolic process	GO:0032268	267	0.024
cellular catabolic process	GO:0044248	295	0.023
regulation of alternative mrna splicing via spliceosome	GO:0000381	2	0.023
embryo development ending in birth or egg hatching	GO:0009792	22	0.023
purinergic receptor signaling pathway	GO:0035587	10	0.023
positive regulation of growth	GO:0045927	55	0.023
positive regulation of signaling	GO:0023056	270	0.023
embryo development	GO:0009790	49	0.022
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.022
regulation of smooth muscle cell proliferation	GO:0048660	75	0.022
regulation of sodium ion transport	GO:0002028	21	0.021
sensory perception of bitter taste	GO:0050913	4	0.021
regulation of ion transport	GO:0043269	245	0.021
hemidesmosome assembly	GO:0031581	1	0.020
positive regulation of gene expression	GO:0010628	244	0.020
response to molecule of bacterial origin	GO:0002237	194	0.020
anterior posterior pattern specification	GO:0009952	1	0.020
positive regulation of response to stimulus	GO:0048584	285	0.019
muscle cell migration	GO:0014812	36	0.019
positive regulation of smooth muscle cell proliferation	GO:0048661	51	0.019
negative regulation of macromolecule metabolic process	GO:0010605	260	0.018
cell cycle process	GO:0022402	57	0.018
response to tumor necrosis factor	GO:0034612	56	0.018
regulation of cell projection organization	GO:0031344	175	0.018
response to other organism	GO:0051707	220	0.018
cellular amino acid metabolic process	GO:0006520	107	0.018
locomotion	GO:0040011	237	0.018
positive regulation of developmental process	GO:0051094	283	0.017
negative regulation of protein metabolic process	GO:0051248	114	0.017
gamete generation	GO:0007276	124	0.017
negative regulation of gene expression	GO:0010629	199	0.017
regulation of cell development	GO:0060284	263	0.017
rhodopsin mediated signaling pathway	GO:0016056	2	0.017
cytosolic calcium ion homeostasis	GO:0051480	140	0.017
apoptotic process	GO:0006915	381	0.016
axis specification	GO:0009798	4	0.016
regulation of neurogenesis	GO:0050767	247	0.016
regulation of neuron projection development	GO:0010975	161	0.016
positive regulation of cell proliferation	GO:0008284	249	0.016
brain development	GO:0007420	247	0.016
phototransduction	GO:0007602	3	0.016
posttranscriptional regulation of gene expression	GO:0010608	37	0.015
negative regulation of metabolic process	GO:0009892	331	0.015
rhythmic process	GO:0048511	156	0.015
positive regulation of cell differentiation	GO:0045597	217	0.015
positive regulation of rna metabolic process	GO:0051254	203	0.015
regulation of anion transport	GO:0044070	43	0.015
response to inorganic substance	GO:0010035	377	0.014
positive regulation of multicellular organismal process	GO:0051240	387	0.014
rna localization	GO:0006403	4	0.014
growth	GO:0040007	165	0.014
dendrite development	GO:0016358	72	0.014
organonitrogen compound catabolic process	GO:1901565	179	0.014
ribonucleoside metabolic process	GO:0009119	174	0.014
response to cytokine	GO:0034097	215	0.014
synaptic transmission	GO:0007268	235	0.014
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.014
anatomical structure morphogenesis	GO:0009653	298	0.013
single organism catabolic process	GO:0044712	283	0.013
intracellular signal transduction	GO:0035556	314	0.013
organic cyclic compound catabolic process	GO:1901361	175	0.013
regulation of signal transduction	GO:0009966	318	0.013
execution phase of apoptosis	GO:0097194	2	0.013
heart morphogenesis	GO:0003007	3	0.013
divalent inorganic cation homeostasis	GO:0072507	165	0.013
meiotic cell cycle process	GO:1903046	3	0.013
cell morphogenesis	GO:0000902	142	0.013
nucleotide metabolic process	GO:0009117	279	0.013
nucleic acid templated transcription	GO:0097659	379	0.013
response to biotic stimulus	GO:0009607	226	0.012
cellular cation homeostasis	GO:0030003	180	0.012
positive regulation of neuron projection development	GO:0010976	99	0.012
negative regulation of calcium ion transport	GO:0051926	14	0.012
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.012
sulfur compound metabolic process	GO:0006790	70	0.012
positive regulation of neuron differentiation	GO:0045666	126	0.012
regulation of p38mapk cascade	GO:1900744	1	0.012
inorganic cation transmembrane transport	GO:0098662	202	0.012
axon guidance	GO:0007411	24	0.012
lipid metabolic process	GO:0006629	283	0.012
calcium ion homeostasis	GO:0055074	162	0.012
cellular response to cytokine stimulus	GO:0071345	127	0.012
carboxylic acid metabolic process	GO:0019752	289	0.012
negative regulation of developmental process	GO:0051093	125	0.012
regulation of translation	GO:0006417	27	0.012
cellular response to oxygen containing compound	GO:1901701	386	0.012
single organism organelle organization	GO:1902589	180	0.012
positive regulation of cell development	GO:0010720	176	0.011
regulation of cellular component biogenesis	GO:0044087	86	0.011
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.011
cellular calcium ion homeostasis	GO:0006874	160	0.011
oxoacid metabolic process	GO:0043436	290	0.011
carbohydrate derivative metabolic process	GO:1901135	346	0.011
chemical homeostasis	GO:0048878	292	0.011
male gamete generation	GO:0048232	99	0.011
smooth muscle cell proliferation	GO:0048659	77	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.011
nucleobase containing compound catabolic process	GO:0034655	152	0.011
regulation of neuron differentiation	GO:0045664	208	0.011
positive regulation of intracellular signal transduction	GO:1902533	138	0.011
positive regulation of neurogenesis	GO:0050769	165	0.011
response to increased oxygen levels	GO:0036296	45	0.011
sodium ion transmembrane transport	GO:0035725	67	0.011
muscle cell proliferation	GO:0033002	84	0.011
cell motility	GO:0048870	202	0.010
response to light stimulus	GO:0009416	52	0.010
peptidyl tyrosine modification	GO:0018212	72	0.010
cell projection morphogenesis	GO:0048858	123	0.010
localization within membrane	GO:0051668	2	0.010
multi multicellular organism process	GO:0044706	138	0.010
regulation of sodium ion transmembrane transporter activity	GO:2000649	4	0.010
spermatogenesis	GO:0007283	99	0.010
embryonic pattern specification	GO:0009880	1	0.010
polyamine biosynthetic process	GO:0006596	4	0.010
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.010
cellular chemical homeostasis	GO:0055082	247	0.010

Ddx3x disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
myopathy	DOID:423	0.079
disease of anatomical entity	DOID:7	0.079
muscular disease	DOID:0080000	0.079
muscle tissue disease	DOID:66	0.079
musculoskeletal system disease	DOID:17	0.079
muscular dystrophy	DOID:9884	0.079

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