Rattus norvegicus

13 known processes

Hspa5

heat shock protein 5

(Aliases: BIP)

Hspa5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chaperone mediated protein foldingGO:006107760.996
er associated ubiquitin dependent protein catabolic processGO:003043310.894
Yeast
protein refoldingGO:004202630.784
protein foldingGO:0006457120.556
regulation of programmed cell deathGO:00430673410.522
Human
cellular response to topologically incorrect proteinGO:003596730.469
Mouse
apoptotic processGO:00069153810.387
Human
organic acid metabolic processGO:00060822920.259
positive regulation of multicellular organismal processGO:00512403870.247
cell chemotaxisGO:0060326310.218
chaperone mediated protein folding requiring cofactorGO:005108520.198
programmed cell deathGO:00125013920.196
Human
regulation of apoptotic processGO:00429813350.181
Human
regulation of cell developmentGO:00602842630.181
regulation of interleukin 6 productionGO:0032675120.167
negative regulation of gene expressionGO:00106291990.152
Fly
negative regulation of programmed cell deathGO:00430691830.149
Human
cellular protein complex assemblyGO:0043623440.144
response to atpGO:0033198130.136
de novo posttranslational protein foldingGO:005108420.135
negative regulation of cell deathGO:00605482290.128
Human
neurological system processGO:00508772190.128
response to nutrient levelsGO:00316673700.125
Human
cellular catabolic processGO:00442482950.121
Yeast Mouse
cellular response to atpGO:007131850.121
positive regulation of cardiac muscle contractionGO:006045240.120
cardiovascular system developmentGO:00723581340.107
negative regulation of apoptotic processGO:00430661810.105
Human
cellular macromolecule catabolic processGO:0044265290.098
Yeast Mouse
response to purine containing compoundGO:00140741260.097
regulation of catalytic activityGO:00507903040.092
Yeast Mouse
circulatory system developmentGO:00723591340.088
regulation of vasculature developmentGO:1901342440.081
cellular response to organonitrogen compoundGO:00714171970.079
blood vessel developmentGO:0001568690.077
regulation of multicellular organismal developmentGO:20000263760.076
actin filament based processGO:0030029860.069
cellular response to organic cyclic compoundGO:00714072020.068
positive regulation of transportGO:00510502450.067
proteolysis involved in cellular protein catabolic processGO:0051603190.067
Yeast Mouse
macromolecular complex assemblyGO:00650032730.066
synaptic vesicle endocytosisGO:004848840.066
b cell activation involved in immune responseGO:000231210.065
cell motilityGO:00488702020.065
Human
striated muscle tissue developmentGO:0014706580.063
polyamine biosynthetic processGO:000659640.063
positive regulation of macromolecule biosynthetic processGO:00105572470.062
positive regulation of cell differentiationGO:00455972170.061
positive regulation of nitrogen compound metabolic processGO:00511733340.060
Mouse
proteolysisGO:00065081750.059
Yeast Mouse
regulation of molecular functionGO:00650093980.059
Yeast Mouse
macromolecular complex subunit organizationGO:00439333390.057
regulation of striated muscle contractionGO:0006942210.055
cellular component biogenesisGO:00440853680.055
muscle structure developmentGO:0061061870.055
regulation of phosphorylationGO:00423252480.055
Mouse
organelle organizationGO:00069962660.054
Yeast Fly
modification dependent protein catabolic processGO:0019941140.053
Yeast
response to tumor cellGO:000234740.053
homeostatic processGO:00425923310.051
organic substance catabolic processGO:19015753160.050
Yeast Mouse
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.049
agingGO:00075682410.049
antigen processing and presentation of peptide antigen via mhc class iGO:000247410.048
cell cell signalingGO:00072673350.048
response to biotic stimulusGO:00096072260.046
Zebrafish Mouse
regulation of ion homeostasisGO:2000021630.046
cytokine productionGO:0001816610.046
positive regulation of biosynthetic processGO:00098913190.044
single organism organelle organizationGO:19025891800.044
Fly
regulation of anatomical structure morphogenesisGO:00226031410.043
cellular component assemblyGO:00226073600.043
myosin filament organizationGO:003103320.042
synaptic transmissionGO:00072682350.042
chemosensory behaviorGO:000763520.042
response to unfolded proteinGO:000698660.042
Yeast Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353190.040
Mouse
transmembrane transportGO:00550854120.040
Yeast
calcium ion homeostasisGO:00550741620.040
regulation of cell differentiationGO:00455953200.039
regulation of phosphorus metabolic processGO:00511743490.039
Mouse
response to organophosphorusGO:00466831020.039
positive regulation of programmed cell deathGO:00430681570.038
retinoic acid receptor signaling pathwayGO:004838470.038
regulation of cellular component organizationGO:00511283680.037
somatic recombination of immunoglobulin genes involved in immune responseGO:000220410.036
catabolic processGO:00090563510.036
Yeast Mouse
positive regulation of response to stimulusGO:00485842850.035
cellular amine metabolic processGO:0044106380.035
carbohydrate derivative metabolic processGO:19011353460.035
Yeast
positive regulation of cellular biosynthetic processGO:00313282950.035
myosin filament assemblyGO:003103410.034
protein phosphorylationGO:00064683450.034
Mouse
rna biosynthetic processGO:00327743800.034
vasculature developmentGO:0001944700.033
somatic diversification of immune receptorsGO:000220020.033
protein complex subunit organizationGO:00718223020.033
angiogenesisGO:0001525530.032
proteasome mediated ubiquitin dependent protein catabolic processGO:004316170.032
Yeast
positive regulation of phosphorus metabolic processGO:00105622620.032
Mouse
positive regulation of protein import into nucleus translocationGO:003316070.032
positive regulation of gene expressionGO:00106282440.031
regulation of protein modification processGO:00313991940.031
Mouse
isotype switching to igg isotypesGO:004829110.031
response to amineGO:0014075460.031
positive regulation of reactive oxygen species biosynthetic processGO:190342820.031
reactive oxygen species metabolic processGO:0072593370.031
neuron differentiationGO:00301823680.031
negative regulation of multicellular organismal processGO:00512412030.031
macromolecule catabolic processGO:0009057580.031
Yeast Mouse
positive regulation of developmental processGO:00510942830.030
negative regulation of metabolic processGO:00098923310.030
Fly
cellular divalent inorganic cation homeostasisGO:00725031620.030
response to inorganic substanceGO:00100353770.029
positive regulation of cell motilityGO:2000147970.029
Human
negative regulation of developmental processGO:00510931250.029
regulation of protein phosphorylationGO:00019321830.029
Mouse
actin filament organizationGO:0007015420.028
response to endoplasmic reticulum stressGO:0034976100.028
negative regulation of macromolecule metabolic processGO:00106052600.027
Fly
anatomical structure morphogenesisGO:00096532980.027
Mouse
protein complex biogenesisGO:00702712630.027
blood vessel morphogenesisGO:0048514580.027
positive regulation of cell developmentGO:00107201760.027
response to hypoxiaGO:00016662310.027
intracellular steroid hormone receptor signaling pathwayGO:0030518200.027
neuromuscular processGO:005090520.027
response to oxygen levelsGO:00704822650.027
cation homeostasisGO:00550801950.027
positive regulation of cytosolic calcium ion concentrationGO:00072041220.026
regulation of reactive oxygen species biosynthetic processGO:190342650.026
cellular response to nitrogen compoundGO:19016992100.026
response to topologically incorrect proteinGO:003596680.025
Yeast Mouse
positive regulation of cell deathGO:00109421840.025
positive regulation of intracellular protein transportGO:0090316200.025
regulation of neuron differentiationGO:00456642080.025
protein catabolic processGO:0030163300.024
Yeast Mouse
chemical homeostasisGO:00488782920.024
synaptic vesicle localizationGO:0097479240.024
ion homeostasisGO:00508012120.024
regulation of protein transportGO:0051223680.024
positive regulation of cellular component organizationGO:00511302000.023
cellular cation homeostasisGO:00300031800.022
regulation of hydrolase activityGO:00513361430.022
Mouse
muscle system processGO:00030121150.022
metal ion homeostasisGO:00550651860.022
apoptotic signaling pathwayGO:0097190270.022
regulation of cellular localizationGO:00603412630.022
divalent inorganic cation homeostasisGO:00725071650.022
regulation of response to tumor cellGO:000283430.022
regulation of secretionGO:00510462240.022
cellular macromolecular complex assemblyGO:0034622580.021
actin cytoskeleton organizationGO:0030036730.021
cytoplasmic transportGO:00164821150.021
Yeast
positive regulation of cytokine productionGO:0001819420.021
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.021
regulation of cell projection organizationGO:00313441750.021
single organism behaviorGO:00447081300.021
dna replicationGO:0006260370.021
positive regulation of angiogenesisGO:0045766280.021
startle responseGO:000196420.021
response to testosteroneGO:0033574550.021
reactive nitrogen species metabolic processGO:200105710.020
interleukin 10 productionGO:003261330.020
interleukin 12 productionGO:003261530.020
protein transmembrane transportGO:007180620.020
Yeast
muscle tissue developmentGO:0060537580.020
dephosphorylationGO:0016311980.020
cellular component morphogenesisGO:00329891550.019
maintenance of locationGO:0051235170.019
Human
response to lipopolysaccharideGO:00324961910.019
regulation of cellular protein metabolic processGO:00322682670.019
Mouse
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.019
locomotionGO:00400112370.019
Human
negative regulation of rna metabolic processGO:00512531230.019
cellular response to unfolded proteinGO:003462020.019
Mouse
cellular response to nutrient levelsGO:0031669600.019
Human
tissue developmentGO:00098882520.019
carbohydrate derivative biosynthetic processGO:19011371240.019
b cell mediated immunityGO:001972440.019
cellular response to stressGO:00335542690.019
response to estrogenGO:00436272320.019
single organism carbohydrate metabolic processGO:00447231180.018
regulation of homeostatic processGO:00328441010.018
positive regulation of apoptotic processGO:00430651540.018
regulation of nervous system developmentGO:00519602640.018
protein complex assemblyGO:00064612630.018
negative regulation of protein phosphorylationGO:0001933440.018
response to heatGO:0009408600.018
endocytosisGO:0006897840.018
transcription dna templatedGO:00063513770.018
muscle contractionGO:0006936880.018
negative regulation of molecular functionGO:00440921330.018
cytosolic calcium ion homeostasisGO:00514801400.018
intracellular transportGO:00469071850.018
Yeast
carboxylic acid metabolic processGO:00197522890.017
de novo protein foldingGO:000645820.017
dna metabolic processGO:0006259960.017
arp2 3 complex mediated actin nucleationGO:003431420.017
regulation of cellular component sizeGO:0032535510.017
sequestering of metal ionGO:005123890.017
toxin transportGO:190199830.017
Mouse
oxoacid metabolic processGO:00434362900.017
regulation of reactive oxygen species metabolic processGO:2000377260.016
circulatory system processGO:00030131830.016
positive regulation of cellular component biogenesisGO:0044089550.016
positive regulation of neurogenesisGO:00507691650.016
regulation of adaptive immune responseGO:000281980.016
somatic recombination of immunoglobulin gene segmentsGO:001644710.016
amine metabolic processGO:0009308380.016
modification dependent macromolecule catabolic processGO:0043632140.016
Yeast
negative regulation of response to stimulusGO:00485851550.016
Mouse
positive regulation of neuron differentiationGO:00456661260.016
head developmentGO:00603222470.015
Human Mouse
regulation of cellular component biogenesisGO:0044087860.015
regulation of cytokine productionGO:0001817560.015
regulation of immune system processGO:00026821230.015
regulation of protein metabolic processGO:00512462890.015
Mouse
positive regulation of muscle contractionGO:0045933220.015
regulation of interferon gamma productionGO:003264930.015
response to decreased oxygen levelsGO:00362932370.015
response to cytokineGO:00340972150.015
Mouse
immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238110.015
response to extracellular stimulusGO:00099913800.015
Human
regulation of angiogenesisGO:0045765390.015
nucleobase containing small molecule metabolic processGO:00550863160.015
Yeast
regulation of cell morphogenesisGO:0022604770.014
negative regulation of cellular protein metabolic processGO:00322691060.014
multicellular organismal reproductive processGO:00486092330.014
immune responseGO:00069551040.014
regulation of systemic arterial blood pressureGO:0003073300.014
negative regulation of rna biosynthetic processGO:19026791180.014
regulation of membrane potentialGO:00423911100.014
positive regulation of protein metabolic processGO:00512471780.014
Mouse
regulation of phosphate metabolic processGO:00192203490.014
Mouse
somatic cell dna recombinationGO:001644420.014
organelle localizationGO:0051640550.014
positive regulation of neuron projection developmentGO:0010976990.014
cellular response to metal ionGO:0071248550.014
positive regulation of nervous system developmentGO:00519621780.013
cellular metal ion homeostasisGO:00068751720.013
localization of cellGO:00516742020.013
Human
regulation of blood circulationGO:19035221100.013
nucleotide metabolic processGO:00091172790.013
Yeast
receptor mediated endocytosisGO:0006898420.013
cation transportGO:00068123820.013
negative regulation of protein metabolic processGO:00512481140.013
anterograde axon cargo transportGO:000808910.013
positive regulation of cell projection organizationGO:00313461110.013
anatomical structure homeostasisGO:0060249290.013
immunoglobulin mediated immune responseGO:001606440.013
nucleoside phosphate metabolic processGO:00067532830.013
Yeast
spermatogenesisGO:0007283990.012
cellular calcium ion homeostasisGO:00068741600.012
olfactory behaviorGO:004204820.012
positive regulation of locomotionGO:00400171020.012
Human
skeletal muscle contractionGO:0003009170.012
positive regulation of phosphorylationGO:00423271770.012
Mouse
negative regulation of nitrogen compound metabolic processGO:00511721610.012
response to estradiolGO:00323551640.012
nucleic acid templated transcriptionGO:00976593790.012
regulation of metal ion transportGO:00109591180.012
regulation of signal transductionGO:00099663180.012
Mouse
cell morphogenesis involved in differentiationGO:00009041190.012
vasoconstrictionGO:0042310540.012
transmission of nerve impulseGO:0019226420.012
negative regulation of cellular metabolic processGO:00313242810.012
negative regulation of cell communicationGO:00106481580.012
Mouse
small gtpase mediated signal transductionGO:0007264360.011
regulation of cellular amine metabolic processGO:003323880.011
proteasomal protein catabolic processGO:001049880.011
Yeast
central nervous system developmentGO:00074173110.011
Human Mouse
reproductionGO:00000032450.011
Yeast
positive regulation of cellular amino acid metabolic processGO:004576410.011
regulation of interleukin 12 productionGO:003265530.011
endoplasmic reticulum unfolded protein responseGO:003096820.011
Mouse
regulation of cell activationGO:0050865500.011
single organism cell adhesionGO:0098602460.011
positive regulation of cell communicationGO:00106472710.011
positive regulation of organelle organizationGO:0010638480.011
regulation of kinase activityGO:00435491170.011
Mouse
macromolecule glycosylationGO:0043413140.011
positive regulation of lamellipodium organizationGO:190274540.011
muscle cell apoptotic processGO:0010657300.011
regulation of immune response to tumor cellGO:000283730.011
neuronal action potentialGO:0019228350.011
immune response to tumor cellGO:000241830.011
regulation of catabolic processGO:00098941130.011
positive regulation of phosphate metabolic processGO:00459372620.011
Mouse
regulation of cardiac muscle contractionGO:0055117170.011
gastrulationGO:000736920.011
positive regulation of cellular amine metabolic processGO:003324030.011
negative regulation of transcription dna templatedGO:00458921160.011
neuron developmentGO:00486662860.010
male gamete generationGO:0048232990.010
regulation of immune effector processGO:0002697320.010
heterocycle catabolic processGO:00467001670.010
Yeast
cellular response to oxygen containing compoundGO:19017013860.010
cell projection organizationGO:00300303020.010
regulation of intracellular transportGO:0032386650.010
response to starvationGO:0042594590.010
Human
cardiocyte differentiationGO:0035051220.010
regulation of cell migrationGO:00303341280.010
Human
divalent inorganic cation transportGO:00725111340.010
regulation of synaptic transmissionGO:00508041410.010
single organism intracellular transportGO:19025821660.010
Yeast
blood circulationGO:00080151830.010
cellular response to inorganic substanceGO:0071241650.010
rna metabolic processGO:00160704060.010
somatic diversification of immunoglobulins involved in immune responseGO:000220810.010
macroautophagyGO:001623640.010

Hspa5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
central nervous system diseaseDOID:33100.017
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
organ system cancerDOID:005068600.011