Rattus norvegicus

54 known processes

Flt4

fms-related tyrosine kinase 4

(Aliases: Vegfr3)

Flt4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
anatomical structure morphogenesisGO:00096532980.395
Human Zebrafish Mouse Rat Fly
cellular response to endogenous stimulusGO:00714953770.239
Rat Fly
response to peptideGO:19016522920.219
Fly
response to estrogenGO:00436272320.214
Rat
positive regulation of cell proliferationGO:00082842490.197
Human Mouse Rat
cellular response to hormone stimulusGO:00328702470.197
Rat Fly
positive regulation of biosynthetic processGO:00098913190.179
Rat
neuron developmentGO:00486662860.169
positive regulation of phosphate metabolic processGO:00459372620.159
Human Rat Fly
apoptotic processGO:00069153810.155
Human Rat Fly
cell projection organizationGO:00300303020.148
Fly
neuron differentiationGO:00301823680.148
response to glucocorticoidGO:00513842230.139
Rat
response to extracellular stimulusGO:00099913800.138
response to inorganic substanceGO:00100353770.123
Rat
regulation of apoptotic processGO:00429813350.123
Human Rat Fly
immune system developmentGO:0002520410.117
Rat Fly
regulation of programmed cell deathGO:00430673410.116
Human Rat Fly
intracellular signal transductionGO:00355563140.112
Human Rat Fly
regulation of phosphate metabolic processGO:00192203490.108
Human Rat Fly
response to campGO:0051591910.108
oxoacid metabolic processGO:00434362900.107
protein phosphorylationGO:00064683450.106
single organism reproductive processGO:00447022970.106
Fly
tissue developmentGO:00098882520.105
Rat Fly
response to oxidative stressGO:00069791860.105
Rat
response to purine containing compoundGO:00140741260.103
regulation of cell proliferationGO:00421273590.102
Human Mouse Rat
cellular component morphogenesisGO:00329891550.099
Fly
response to nutrient levelsGO:00316673700.095
reproductive processGO:00224143720.095
Fly
response to organophosphorusGO:00466831020.092
protein complex subunit organizationGO:00718223020.088
Fly
growthGO:00400071650.086
regulation of intracellular signal transductionGO:19025312180.084
Human Rat Fly
positive regulation of multicellular organismal processGO:00512403870.081
Human Rat
response to estradiolGO:00323551640.081
Rat
cellular response to oxygen containing compoundGO:19017013860.080
Fly
regulation of phosphorus metabolic processGO:00511743490.079
Human Rat Fly
response to hexoseGO:00097461440.078
oligopeptide transportGO:000685740.078
cellular component biogenesisGO:00440853680.077
Fly
carbohydrate derivative metabolic processGO:19011353460.072
Rat
regulation of multicellular organismal developmentGO:20000263760.071
Rat
positive regulation of cellular biosynthetic processGO:00313282950.070
peptidyl amino acid modificationGO:00181931260.069
response to corticosteroidGO:00319602350.067
Rat
response to carbohydrateGO:00097431830.066
cation transportGO:00068123820.066
regulation of rna metabolic processGO:00512523910.065
calcium ion transportGO:00068161310.064
negative regulation of cell deathGO:00605482290.062
Human Rat Fly
homeostatic processGO:00425923310.061
Rat Fly
regulation of immune system processGO:00026821230.061
Rat Fly
response to nutrientGO:00075842480.060
regulation of cell differentiationGO:00455953200.060
Rat Fly
gland developmentGO:00487321550.060
Fly
multi organism reproductive processGO:00447032620.058
Fly
cell morphogenesis involved in differentiationGO:00009041190.058
action potentialGO:0001508540.058
response to peptide hormoneGO:00434342780.057
Fly
neuron projection developmentGO:00311752730.057
cell morphogenesisGO:00009021420.055
Fly
chemical homeostasisGO:00488782920.055
cellular response to lipidGO:00713962010.054
Rat
positive regulation of macromolecule biosynthetic processGO:00105572470.054
Rat
lymphoid progenitor cell differentiationGO:000232020.054
Rat
ion transmembrane transportGO:00342203650.053
locomotionGO:00400112370.052
Human Zebrafish Rat Fly
multicellular organism reproductionGO:00325042330.052
Fly
programmed cell deathGO:00125013920.051
Human Rat Fly
regulation of system processGO:00440572080.050
Rat
protein complex assemblyGO:00064612630.050
leukocyte differentiationGO:0002521300.049
Rat
positive regulation of gene expressionGO:00106282440.049
regulation of cellular component organizationGO:00511283680.049
response to decreased oxygen levelsGO:00362932370.047
Rat
neurological system processGO:00508772190.047
neuron projection morphogenesisGO:00488121220.046
macromolecular complex subunit organizationGO:00439333390.046
Fly
regulation of nervous system developmentGO:00519602640.045
cellular response to stressGO:00335542690.045
Human Fly
negative regulation of programmed cell deathGO:00430691830.045
Human Rat Fly
negative regulation of macromolecule metabolic processGO:00106052600.045
carboxylic acid metabolic processGO:00197522890.045
positive regulation of nitrogen compound metabolic processGO:00511733340.044
amine metabolic processGO:0009308380.044
divalent inorganic cation transportGO:00725111340.044
negative regulation of metabolic processGO:00098923310.044
neuron deathGO:00709971270.043
regulation of signal transductionGO:00099663180.043
Human Rat Fly
negative regulation of apoptotic processGO:00430661810.043
Human Rat Fly
organic acid metabolic processGO:00060822920.041
cellular metal ion homeostasisGO:00068751720.041
negative regulation of cellular metabolic processGO:00313242810.041
cellular response to organonitrogen compoundGO:00714171970.041
Fly
organonitrogen compound biosynthetic processGO:19015661670.041
Rat
ion homeostasisGO:00508012120.041
cellular macromolecule localizationGO:00707271220.041
organelle organizationGO:00069962660.041
Fly
positive regulation of nervous system developmentGO:00519621780.040
positive regulation of neuron differentiationGO:00456661260.040
cellular amino acid metabolic processGO:00065201070.040
positive regulation of cell communicationGO:00106472710.040
Human Rat Fly
regulation of cell developmentGO:00602842630.039
regulation of transcription dna templatedGO:00063553740.039
cation homeostasisGO:00550801950.039
cell morphogenesis involved in neuron differentiationGO:00486671060.039
response to metal ionGO:00100382530.039
regulation of neurogenesisGO:00507672470.039
positive regulation of nucleobase containing compound metabolic processGO:00459353190.038
heart morphogenesisGO:000300730.038
cellular ion homeostasisGO:00068731840.037
regulation of cellular ketone metabolic processGO:0010565270.036
cellular chemical homeostasisGO:00550822470.036
behaviorGO:00076102050.036
positive regulation of rna metabolic processGO:00512542030.036
taxisGO:0042330670.036
stress activated protein kinase signaling cascadeGO:0031098370.036
Human
regulation of growthGO:00400081050.035
cellular component movementGO:00069282480.035
Human Zebrafish Rat Fly
cellular protein localizationGO:00346131220.035
cellular amine metabolic processGO:0044106380.035
positive regulation of protein modification processGO:00314011420.034
Human Rat
amide transportGO:00428861050.034
positive regulation of neurogenesisGO:00507691650.034
response to monosaccharideGO:00342841590.034
positive regulation of response to stimulusGO:00485842850.034
Human Rat Fly
regulation of neuron differentiationGO:00456642080.034
cellular calcium ion homeostasisGO:00068741600.034
regulation of phosphorylationGO:00423252480.034
Human Rat Fly
hematopoietic or lymphoid organ developmentGO:0048534360.033
Rat Fly
response to transition metal nanoparticleGO:19902671220.033
cell projection morphogenesisGO:00488581230.033
anion transportGO:00068201780.032
positive regulation of signal transductionGO:00099671750.032
Human Rat Fly
hemopoiesisGO:0030097340.032
Rat Fly
response to radiationGO:00093141370.032
positive regulation of cell differentiationGO:00455972170.032
Rat
cellular homeostasisGO:00197252520.032
response to cytokineGO:00340972150.031
Rat
antibiotic transportGO:004289120.031
regulation of nucleic acid templated transcriptionGO:19035063800.031
response to glucoseGO:00097491360.031
response to oxygen levelsGO:00704822650.031
Rat
regulation of neuron deathGO:19012141150.031
cell part morphogenesisGO:00329901230.031
intestinal absorptionGO:005089230.030
regulation of protein metabolic processGO:00512462890.030
Human Rat
reproductionGO:00000032450.030
Fly
positive regulation of developmental processGO:00510942830.030
Rat
positive regulation of phosphorylationGO:00423271770.030
Human Rat Fly
positive regulation of cellular component organizationGO:00511302000.030
immune system processGO:00023762040.029
Rat Fly
cellular cation homeostasisGO:00300031800.029
positive regulation of cell developmentGO:00107201760.029
positive regulation of phosphorus metabolic processGO:00105622620.029
Human Rat Fly
nuclear transportGO:0051169490.029
regulation of molecular functionGO:00650093980.028
Rat
transmembrane transportGO:00550854120.028
single organism biosynthetic processGO:00447113420.028
Rat
developmental process involved in reproductionGO:00030061590.028
Fly
lipid biosynthetic processGO:00086101280.028
positive regulation of catalytic activityGO:00430851840.027
Rat
metal ion transportGO:00300012890.027
female pregnancyGO:00075651220.027
organophosphate metabolic processGO:00196373700.027
negative regulation of gene expressionGO:00106291990.027
regulation of catalytic activityGO:00507903040.027
Rat
myeloid cell differentiationGO:0030099220.027
Rat
macromolecule localizationGO:00330362520.026
cellular component assemblyGO:00226073600.026
Fly
regulation of membrane potentialGO:00423911100.026
sensory organ developmentGO:0007423740.026
Rat
single organism organelle organizationGO:19025891800.026
Fly
regulation of cellular amine metabolic processGO:003323880.026
cellular ketone metabolic processGO:0042180510.026
carbohydrate derivative biosynthetic processGO:19011371240.026
Rat
divalent metal ion transportGO:00708381320.025
ribonucleotide metabolic processGO:00092592310.025
smooth muscle cell proliferationGO:0048659770.025
Rat
nucleocytoplasmic transportGO:0006913480.025
g protein coupled receptor signaling pathwayGO:00071862420.025
response to growth factorGO:00708481890.025
positive regulation of nucleic acid templated transcriptionGO:19035081970.025
adult locomotory behaviorGO:000834440.025
positive regulation of smooth muscle cell proliferationGO:0048661510.025
Rat
response to lipopolysaccharideGO:00324961910.024
vesicle mediated transportGO:00161921810.024
regulation of cell projection organizationGO:00313441750.024
cell motilityGO:00488702020.024
Human Zebrafish Rat Fly
regulation of cellular amino acid metabolic processGO:000652120.024
negative regulation of nitrogen compound metabolic processGO:00511721610.024
circulatory system processGO:00030131830.024
reproductive system developmentGO:00614581280.024
Fly
organ morphogenesisGO:0009887750.023
Rat Fly
epithelial cell proliferationGO:0050673540.023
Human
regulation of protein phosphorylationGO:00019321830.023
Human Rat
regulation of transferase activityGO:00513381230.022
Rat
reactive oxygen species metabolic processGO:0072593370.022
macromolecular complex assemblyGO:00650032730.022
multicellular organismal signalingGO:0035637440.022
cytoplasmic transportGO:00164821150.022
lipid metabolic processGO:00066292830.022
positive regulation of cytosolic calcium ion concentrationGO:00072041220.022
localization of cellGO:00516742020.022
Human Zebrafish Rat Fly
single organism behaviorGO:00447081300.021
rna metabolic processGO:00160704060.021
positive regulation of intracellular signal transductionGO:19025331380.021
Human Rat Fly
cellular response to oxidative stressGO:0034599760.021
regulation of anatomical structure sizeGO:00900661350.021
protein targetingGO:0006605610.020
intracellular transportGO:00469071850.020
epithelium developmentGO:0060429960.020
Fly
nucleic acid templated transcriptionGO:00976593790.020
protein localizationGO:00081041910.020
gamete generationGO:00072761240.020
Fly
regulation of metal ion transportGO:00109591180.019
positive regulation of immune system processGO:0002684900.019
Rat
cellular response to peptideGO:19016531330.019
Fly
salivary gland developmentGO:000743130.019
Fly
sodium independent organic anion transportGO:004325220.019
myeloid leukocyte differentiationGO:0002573200.019
Rat
divalent inorganic cation homeostasisGO:00725071650.019
peptidyl tyrosine phosphorylationGO:0018108720.019
tangential migration from the subventricular zone to the olfactory bulbGO:002202810.019
cerebral cortex tangential migrationGO:002180010.018
brain developmentGO:00074202470.018
transcription dna templatedGO:00063513770.018
cellular response to glucocorticoid stimulusGO:0071385680.018
Rat
response to molecule of bacterial originGO:00022371940.018
regulation of rna biosynthetic processGO:20011413810.018
peptidyl tyrosine modificationGO:0018212720.018
positive regulation of signalingGO:00230562700.018
Human Rat Fly
cellular response to cytokine stimulusGO:00713451270.017
Rat
positive regulation of molecular functionGO:00440932300.017
Rat
single organism intracellular transportGO:19025821660.017
purine nucleotide metabolic processGO:00061632290.017
cell type specific apoptotic processGO:00972851340.017
calcium ion homeostasisGO:00550741620.017
b cell differentiationGO:003018320.017
Rat
nucleotide metabolic processGO:00091172790.017
spermatogenesisGO:0007283990.017
response to reactive oxygen speciesGO:00003021200.017
Rat
regenerationGO:00310991630.017
Rat
multicellular organismal reproductive processGO:00486092330.017
Fly
nucleoside phosphate metabolic processGO:00067532830.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
positive regulation of apoptotic processGO:00430651540.017
cellular response to growth factor stimulusGO:00713631620.016
axon developmentGO:0061564960.016
cytosolic calcium ion homeostasisGO:00514801400.016
synaptic vesicle localizationGO:0097479240.016
multicellular organismal homeostasisGO:0048871490.016
Rat
agingGO:00075682410.016
neuron apoptotic processGO:0051402880.016
organ formationGO:004864530.016
mesoderm developmentGO:000749820.016
negative regulation of cell proliferationGO:00082851190.016
Rat
negative regulation of biosynthetic processGO:00098901680.016
nuclear importGO:0051170350.016
gastrulationGO:000736920.016
regulation of neuron projection developmentGO:00109751610.016
nucleobase containing small molecule metabolic processGO:00550863160.016
establishment of protein localizationGO:00451841410.016
protein complex biogenesisGO:00702712630.015
regulation of jak stat cascadeGO:0046425210.015
regulation of response to stressGO:00801341260.015
Human
regulation of peptide transportGO:0090087870.015
sexual reproductionGO:00199531480.015
Fly
regulation of nucleotide metabolic processGO:00061401170.015
sex differentiationGO:00075481130.015
Fly
steroid metabolic processGO:0008202730.015
hematopoietic progenitor cell differentiationGO:000224420.015
Rat
actin cytoskeleton organizationGO:0030036730.015
Fly
regulation of kinase activityGO:00435491170.015
Rat
ribose phosphate metabolic processGO:00196932350.015
male gamete generationGO:0048232990.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
carbohydrate homeostasisGO:0033500750.015
positive regulation of cellular protein metabolic processGO:00322701670.015
Human Rat
cellular response to hexose stimulusGO:0071331650.015
male sex differentiationGO:0046661640.015
Fly
positive regulation of cell projection organizationGO:00313461110.015
positive regulation of locomotionGO:00400171020.015
Human Rat
positive regulation of protein kinase activityGO:0045860730.015
Rat
positive regulation of programmed cell deathGO:00430681570.015
response to ketoneGO:19016541820.015
intracellular protein transportGO:0006886790.014
regulation of cell morphogenesis involved in differentiationGO:0010769720.014
positive regulation of protein phosphorylationGO:00019341350.014
Human Rat
cellular divalent inorganic cation homeostasisGO:00725031620.014
hepaticobiliary system developmentGO:0061008900.014
protein oligomerizationGO:00512591910.014
regulation of epithelial cell proliferationGO:0050678490.014
Human
liver developmentGO:0001889900.014
positive regulation of cell deathGO:00109421840.014
regulation of lipid metabolic processGO:0019216680.014
positive regulation of protein metabolic processGO:00512471780.014
Human Rat
regulation of cellular localizationGO:00603412630.014
negative regulation of response to stimulusGO:00485851550.014
retinal ganglion cell axon guidanceGO:003129010.014
alpha amino acid metabolic processGO:1901605710.014
response to toxic substanceGO:00096361330.013
Rat
cell cell signalingGO:00072673350.013
protein import into nucleusGO:0006606350.013
negative regulation of rna metabolic processGO:00512531230.013
cell cell signaling involved in cell fate commitmentGO:004516820.013
response to ethanolGO:00454711620.013
substrate dependent cerebral cortex tangential migrationGO:002182510.013
cellular response to alcoholGO:0097306870.013
comma shaped body morphogenesisGO:007204920.013
Rat
jak stat cascadeGO:0007259260.013
protein localization to nucleusGO:0034504390.013
regulation of cell migrationGO:00303341280.013
Human Rat
transmission of nerve impulseGO:0019226420.013
visual perceptionGO:000760130.013
negative regulation of transcription dna templatedGO:00458921160.013
response to acid chemicalGO:00011012220.013
Rat
sensory perception of light stimulusGO:005095330.013
oxidation reduction processGO:00551143040.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.012
purine ribonucleotide metabolic processGO:00091502270.012
positive regulation of neuron projection developmentGO:0010976990.012
cerebral cortex cell migrationGO:002179540.012
central nervous system developmentGO:00074173110.012
Fly
circulatory system developmentGO:00723591340.012
Human Zebrafish Mouse
multicellular organism growthGO:003526410.012
response to bacteriumGO:00096172000.012
cardiovascular system developmentGO:00723581340.012
Human Zebrafish Mouse
glycosyl compound metabolic processGO:19016571820.012
muscle tissue morphogenesisGO:006041510.012
organic hydroxy compound metabolic processGO:19016151150.012
respiratory system developmentGO:0060541450.012
reproductive structure developmentGO:00486081280.012
Fly
developmental growthGO:00485891000.012
muscle cell proliferationGO:0033002840.012
Rat
cell chemotaxisGO:0060326310.012
inorganic ion transmembrane transportGO:00986602290.012
cellular response to reactive oxygen speciesGO:0034614550.012
cytoskeleton organizationGO:00070101110.012
Fly
negative regulation of developmental processGO:00510931250.012
Rat
regulation of neuron apoptotic processGO:0043523830.012
inner ear receptor cell differentiationGO:006011320.012
glutathione transportGO:003463520.012
regulation of homeostatic processGO:00328441010.012
Rat
protein heterooligomerizationGO:0051291890.012
cellular response to external stimulusGO:00714961180.012
negative regulation of rna biosynthetic processGO:19026791180.011
positive regulation of secretion by cellGO:19035321280.011
detection of visible lightGO:000958430.011
cell cell junction organizationGO:0045216200.011
cgmp biosynthetic processGO:0006182150.011
regulation of endothelial cell apoptotic processGO:200035130.011
endomembrane system organizationGO:0010256480.011
response to hydrogen peroxideGO:0042542890.011
Rat
protein transportGO:00150311320.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
cellular response to steroid hormone stimulusGO:0071383930.011
Rat
positive regulation of cellular amine metabolic processGO:003324030.011
urogenital system developmentGO:0001655780.011
Rat Fly
regulation of protein modification processGO:00313991940.011
Human Rat
developmental growth involved in morphogenesisGO:0060560330.011
negative regulation of cellular biosynthetic processGO:00313271610.011
establishment of tissue polarityGO:000716420.011
hormone biosynthetic processGO:0042446250.011
phospholipid metabolic processGO:0006644610.011
tube developmentGO:0035295890.011
Fly
neuron projection extensionGO:1990138260.011
regulation of calcium ion transportGO:0051924770.011
regulation of cell growthGO:0001558850.011
regulation of hormone levelsGO:00108171870.011
actin filament based processGO:0030029860.011
Fly
mechanoreceptor differentiationGO:004249020.011
dendrite developmentGO:0016358720.011
positive regulation of kinase activityGO:0033674770.011
Rat
regulation of nucleocytoplasmic transportGO:0046822280.011
development of primary male sexual characteristicsGO:0046546590.011
forebrain neuron developmentGO:002188430.011
cellular catabolic processGO:00442482950.011
response to external biotic stimulusGO:00432072210.011
Fly
response to ionizing radiationGO:0010212590.011
negative regulation of molecular functionGO:00440921330.010
cellular response to nitrogen compoundGO:19016992100.010
Fly
neuronal action potentialGO:0019228350.010
response to fungicideGO:0060992200.010
purine nucleoside metabolic processGO:00422781690.010
protein autophosphorylationGO:0046777660.010
Human Rat
anatomical structure homeostasisGO:0060249290.010
Rat
endochondral bone growthGO:000341630.010
regulation of stem cell differentiationGO:200073620.010
rna biosynthetic processGO:00327743800.010
cell adhesionGO:00071551100.010
bone developmentGO:0060348250.010
regulation of dna metabolic processGO:0051052600.010
regulation of intracellular transportGO:0032386650.010
positive regulation of nucleotide metabolic processGO:0045981910.010
tongue morphogenesisGO:004358730.010
single organism nuclear importGO:1902593350.010
fertilizationGO:000956630.010
positive regulation of transferase activityGO:0051347810.010
Rat
sulfur compound metabolic processGO:0006790700.010
leukocyte activationGO:0045321760.010
Rat
ribonucleoside metabolic processGO:00091191740.010

Flt4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.037
sensory system diseaseDOID:005015500.037
disease of anatomical entityDOID:700.037
Human
eye and adnexa diseaseDOID:149200.028
retinal diseaseDOID:567900.028
eye diseaseDOID:561400.028
musculoskeletal system diseaseDOID:1700.019
retinal degenerationDOID:846600.017
bone diseaseDOID:008000100.016
bone development diseaseDOID:008000600.016
connective tissue diseaseDOID:6500.016
disease of metabolismDOID:001466700.014
cardiovascular system diseaseDOID:128700.013
disease of cellular proliferationDOID:1456600.011