IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Eif3b

eukaryotic translation initiation factor 3, subunit B

(Aliases: MGC112720,Eif3s9)

Ensembl: ENSRNOG00000001253
RGD: 1309018
Entrez: 288516
UniProtKB: Q4G061

Process Predictions
Disease Predictions

Eif3b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
trna aminoacylation for protein translation	GO:0006418	3	0.746
trna aminoacylation	GO:0043039	3	0.406
rna metabolic process	GO:0016070	406	0.284
regulation of gene expression epigenetic	GO:0040029	10	0.199
amino acid activation	GO:0043038	3	0.130
trna metabolic process	GO:0006399	4	0.116
transcription dna templated	GO:0006351	377	0.111
organic acid metabolic process	GO:0006082	292	0.109
oxoacid metabolic process	GO:0043436	290	0.079
negative regulation of macromolecule metabolic process	GO:0010605	260	0.065
carboxylic acid metabolic process	GO:0019752	289	0.064
positive regulation of gene expression	GO:0010628	244	0.061
cellular amino acid metabolic process	GO:0006520	107	0.061
translation	GO:0006412	35	0.057	Human Yeast Mouse
regulation of protein metabolic process	GO:0051246	289	0.056	Human
single organism reproductive process	GO:0044702	297	0.053
ncrna metabolic process	GO:0034660	8	0.051
nucleocytoplasmic transport	GO:0006913	48	0.050
nucleic acid templated transcription	GO:0097659	379	0.048
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.048
reproductive system development	GO:0061458	128	0.048
organelle organization	GO:0006996	266	0.046
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.043
amine metabolic process	GO:0009308	38	0.042
regulation of transcription dna templated	GO:0006355	374	0.041
eye development	GO:0001654	50	0.041
rna biosynthetic process	GO:0032774	380	0.040
alpha amino acid biosynthetic process	GO:1901607	23	0.039
negative regulation of metabolic process	GO:0009892	331	0.039
negative regulation of gene expression	GO:0010629	199	0.038
central nervous system development	GO:0007417	311	0.036
organophosphate metabolic process	GO:0019637	370	0.036
head development	GO:0060322	247	0.036
regulation of phosphate metabolic process	GO:0019220	349	0.034
lipid transport	GO:0006869	61	0.034
regulation of nucleic acid templated transcription	GO:1903506	380	0.033
negative regulation of biosynthetic process	GO:0009890	168	0.032
cellular amine metabolic process	GO:0044106	38	0.030
regulation of rna metabolic process	GO:0051252	391	0.028
positive regulation of rna biosynthetic process	GO:1902680	197	0.027
tissue development	GO:0009888	252	0.027	Zebrafish
transcription from rna polymerase ii promoter	GO:0006366	252	0.026
organonitrogen compound biosynthetic process	GO:1901566	167	0.026
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.026
regulation of cellular protein metabolic process	GO:0032268	267	0.026	Human
ribonucleotide metabolic process	GO:0009259	231	0.025
gastrulation	GO:0007369	2	0.025
positive regulation of cell death	GO:0010942	184	0.025
nucleoside phosphate biosynthetic process	GO:1901293	102	0.025
negative regulation of developmental process	GO:0051093	125	0.025
positive regulation of biosynthetic process	GO:0009891	319	0.025
positive regulation of developmental process	GO:0051094	283	0.024
reproductive process	GO:0022414	372	0.024
reproduction	GO:0000003	245	0.023	Worm
chromatin modification	GO:0016568	33	0.023
brainstem development	GO:0003360	3	0.023
protein oligomerization	GO:0051259	191	0.023
eye morphogenesis	GO:0048592	4	0.023
positive regulation of cellular protein metabolic process	GO:0032270	167	0.023
response to inorganic substance	GO:0010035	377	0.022
negative regulation of rna biosynthetic process	GO:1902679	118	0.021
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.021
brain development	GO:0007420	247	0.021
embryo development	GO:0009790	49	0.021	Zebrafish Worm
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.021
cellular response to growth factor stimulus	GO:0071363	162	0.020
endocytosis	GO:0006897	84	0.020	Worm
developmental process involved in reproduction	GO:0003006	159	0.020
chromatin organization	GO:0006325	34	0.020
regulation of dna methylation	GO:0044030	6	0.020
response to external biotic stimulus	GO:0043207	221	0.019
cellular component biogenesis	GO:0044085	368	0.019
macromolecular complex subunit organization	GO:0043933	339	0.019
nucleotide metabolic process	GO:0009117	279	0.019
positive regulation of cellular biosynthetic process	GO:0031328	295	0.019
forebrain development	GO:0030900	98	0.018
mrna 3 end processing	GO:0031124	1	0.018
spindle organization	GO:0007051	2	0.018
reproductive structure development	GO:0048608	128	0.017
neuron differentiation	GO:0030182	368	0.017
cellular response to oxygen levels	GO:0071453	60	0.016
triglyceride homeostasis	GO:0070328	2	0.016
regulation of translation	GO:0006417	27	0.016	Human
monocarboxylic acid transport	GO:0015718	52	0.016
sex differentiation	GO:0007548	113	0.016
macromolecular complex assembly	GO:0065003	273	0.015
positive regulation of cell proliferation	GO:0008284	249	0.015
regulation of apoptotic process	GO:0042981	335	0.015
cellular response to stress	GO:0033554	269	0.015
programmed cell death	GO:0012501	392	0.015	Worm
multi organism reproductive process	GO:0044703	262	0.015
protein phosphorylation	GO:0006468	345	0.015
cell cycle	GO:0007049	101	0.015
intracellular transport	GO:0046907	185	0.015
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.014
alpha amino acid metabolic process	GO:1901605	71	0.014
negative regulation of cellular metabolic process	GO:0031324	281	0.014
organic anion transport	GO:0015711	132	0.014
organic hydroxy compound biosynthetic process	GO:1901617	51	0.014
regulation of phosphorylation	GO:0042325	248	0.014
positive regulation of transcription factor import into nucleus	GO:0042993	4	0.013
negative regulation of serine type endopeptidase activity	GO:1900004	1	0.013
negative regulation of rna metabolic process	GO:0051253	123	0.013
response to carbohydrate	GO:0009743	183	0.013
cytoplasmic transport	GO:0016482	115	0.013
response to growth factor	GO:0070848	189	0.013
polyamine biosynthetic process	GO:0006596	4	0.013
positive regulation of phosphorylation	GO:0042327	177	0.013
response to monosaccharide	GO:0034284	159	0.013
chromatin assembly or disassembly	GO:0006333	1	0.013
response to other organism	GO:0051707	220	0.012
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.012
organophosphate biosynthetic process	GO:0090407	143	0.012
regeneration	GO:0031099	163	0.012
protein complex subunit organization	GO:0071822	302	0.012
chromosome organization	GO:0051276	36	0.012
regulation of proteasomal protein catabolic process	GO:0061136	4	0.012
translational initiation	GO:0006413	8	0.012	Human Yeast Mouse
positive regulation of protein metabolic process	GO:0051247	178	0.012
nucleobase containing small molecule metabolic process	GO:0055086	316	0.012
positive regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032436	3	0.012
regulation of mrna splicing via spliceosome	GO:0048024	3	0.012
multicellular organismal reproductive process	GO:0048609	233	0.012
cellular biogenic amine biosynthetic process	GO:0042401	4	0.012
nucleotide biosynthetic process	GO:0009165	98	0.012
positive regulation of transcription dna templated	GO:0045893	197	0.011
macroautophagy	GO:0016236	4	0.011
ncrna processing	GO:0034470	3	0.011
negative regulation of cellular protein metabolic process	GO:0032269	106	0.011
telencephalon development	GO:0021537	62	0.011
protein complex assembly	GO:0006461	263	0.011
negative regulation of neuron death	GO:1901215	69	0.011
heart development	GO:0007507	72	0.010	Zebrafish
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	3	0.010
coenzyme metabolic process	GO:0006732	86	0.010
neuron projection morphogenesis	GO:0048812	122	0.010
epithelial cell proliferation	GO:0050673	54	0.010

Eif3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
neuropathy	DOID:870	0.110
disease of anatomical entity	DOID:7	0.110
neuromuscular disease	DOID:440	0.110
nervous system disease	DOID:863	0.110
charcot marie tooth disease type 2	DOID:0050539	0.055
charcot marie tooth disease	DOID:10595	0.055
muscle tissue disease	DOID:66	0.019
myopathy	DOID:423	0.019
dilated cardiomyopathy	DOID:12930	0.019
musculoskeletal system disease	DOID:17	0.019
heart disease	DOID:114	0.019
muscular disease	DOID:0080000	0.019
intrinsic cardiomyopathy	DOID:0060036	0.019
cardiovascular system disease	DOID:1287	0.019
cardiomyopathy	DOID:0050700	0.019
cancer	DOID:162	0.011
disease of cellular proliferation	DOID:14566	0.011
central nervous system disease	DOID:331	0.011
organ system cancer	DOID:0050686	0.010

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