Rattus norvegicus

43 known processes

Cfl1

cofilin 1, non-muscle

Cfl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
actin filament based processGO:0030029860.524
Yeast Mouse
cellular component biogenesisGO:00440853680.421
cell motilityGO:00488702020.405
Mouse
skeletal muscle fiber adaptationGO:004350310.366
immune responseGO:00069551040.286
macromolecular complex assemblyGO:00650032730.286
macromolecular complex subunit organizationGO:00439333390.285
Yeast Mouse
organic substance catabolic processGO:19015753160.276
purine ribonucleoside triphosphate metabolic processGO:00092051400.235
positive regulation of cellular component organizationGO:00511302000.211
Mouse
tissue developmentGO:00098882520.209
Mouse
actin cytoskeleton organizationGO:0030036730.208
Yeast Mouse
cellular component assemblyGO:00226073600.191
positive regulation of macromolecule biosynthetic processGO:00105572470.190
central nervous system developmentGO:00074173110.190
protein complex biogenesisGO:00702712630.174
regulation of organelle organizationGO:0033043800.167
Mouse
regulation of locomotionGO:00400121480.158
endocytosisGO:0006897840.147
Yeast
protein complex subunit organizationGO:00718223020.145
Yeast Mouse
positive regulation of dna metabolic processGO:0051054390.118
anatomical structure morphogenesisGO:00096532980.117
Human Mouse
head developmentGO:00603222470.109
biological adhesionGO:00226101100.108
chemical homeostasisGO:00488782920.094
regulation of hydrolase activityGO:00513361430.094
macromolecule localizationGO:00330362520.093
response to woundingGO:00096112540.093
regulation of cellular component organizationGO:00511283680.093
Human Mouse
response to ethanolGO:00454711620.091
purine nucleoside triphosphate metabolic processGO:00091441410.091
response to insulinGO:00328681330.090
histamine secretion by mast cellGO:000255330.089
purine containing compound metabolic processGO:00725212530.089
heart morphogenesisGO:000300730.088
purine ribonucleoside triphosphate catabolic processGO:00092071220.084
protein complex assemblyGO:00064612630.083
negative regulation of nucleic acid templated transcriptionGO:19035071170.081
dna metabolic processGO:0006259960.081
mast cell mediated immunityGO:0002448100.080
mast cell activationGO:0045576150.076
wound healingGO:00420601220.076
agingGO:00075682410.076
ribose phosphate metabolic processGO:00196932350.076
regulation of actin polymerization or depolymerizationGO:0008064120.075
Mouse
response to lithium ionGO:0010226280.071
smad protein complex assemblyGO:000718310.071
guanosine containing compound metabolic processGO:1901068740.070
cardiovascular system developmentGO:00723581340.066
regulation of dna metabolic processGO:0051052600.066
regulation of rna biosynthetic processGO:20011413810.064
single organism organelle organizationGO:19025891800.064
Yeast Mouse
actomyosin structure organizationGO:0031032220.063
cellular macromolecule localizationGO:00707271220.062
cell projection organizationGO:00300303020.059
leukocyte activationGO:0045321760.057
purine nucleoside monophosphate metabolic processGO:0009126840.057
muscle contractionGO:0006936880.057
positive regulation of nucleobase containing compound metabolic processGO:00459353190.057
carbohydrate catabolic processGO:0016052400.057
protein localizationGO:00081041910.057
transmembrane transportGO:00550854120.056
multicellular organismal reproductive processGO:00486092330.055
negative regulation of nucleobase containing compound metabolic processGO:00459341530.055
cellular cation homeostasisGO:00300031800.055
cellular metal ion homeostasisGO:00068751720.055
cytokinetic processGO:003250610.054
localization of cellGO:00516742020.054
Mouse
homeostatic processGO:00425923310.053
ribonucleotide catabolic processGO:00092611360.053
secretionGO:00469033070.053
response to glucoseGO:00097491360.052
negative regulation of macromolecule metabolic processGO:00106052600.051
neuron projection developmentGO:00311752730.051
Human
nucleoside monophosphate metabolic processGO:0009123930.050
transcription dna templatedGO:00063513770.050
regulation of cell morphogenesisGO:0022604770.049
Human
cytoskeleton dependent cytokinesisGO:006164020.049
Mouse
organophosphate metabolic processGO:00196373700.048
nucleotide metabolic processGO:00091172790.047
positive regulation of nitrogen compound metabolic processGO:00511733340.047
defense responseGO:00069521940.047
purine nucleoside metabolic processGO:00422781690.047
positive regulation of cellular component movementGO:00512721020.046
brain developmentGO:00074202470.045
actin filament cappingGO:005169320.045
rna metabolic processGO:00160704060.045
cellular protein complex assemblyGO:0043623440.045
growthGO:00400071650.045
response to carbohydrateGO:00097431830.044
negative regulation of signalingGO:00230571570.044
cell cycle processGO:0022402570.044
Mouse
regulation of immune system processGO:00026821230.043
response to inorganic substanceGO:00100353770.043
calcium ion homeostasisGO:00550741620.043
cell part morphogenesisGO:00329901230.042
Human
regulation of protein complex assemblyGO:0043254330.042
cellular component morphogenesisGO:00329891550.042
Human
cellular ion homeostasisGO:00068731840.042
purine nucleoside catabolic processGO:00061521240.041
negative regulation of actin filament polymerizationGO:003083740.041
response to oxidative stressGO:00069791860.041
sequestering of metal ionGO:005123890.040
cellular modified amino acid metabolic processGO:0006575610.040
negative regulation of gene expressionGO:00106291990.040
heart developmentGO:0007507720.039
cytoskeleton organizationGO:00070101110.039
Human Yeast Mouse
positive regulation of cellular component biogenesisGO:0044089550.039
response to cytokineGO:00340972150.039
nitrogen compound transportGO:00717052290.039
rna biosynthetic processGO:00327743800.039
neuron developmentGO:00486662860.038
Human
negative regulation of metabolic processGO:00098923310.038
nucleoside metabolic processGO:00091161790.038
negative regulation of programmed cell deathGO:00430691830.037
intracellular protein transportGO:0006886790.037
positive regulation of transcription dna templatedGO:00458931970.037
regulation of nucleic acid templated transcriptionGO:19035063800.037
actin filament organizationGO:0007015420.036
Yeast Mouse
response to peptide hormoneGO:00434342780.035
cellular response to oxygen containing compoundGO:19017013860.035
purine ribonucleoside monophosphate catabolic processGO:0009169550.035
cell projection morphogenesisGO:00488581230.035
Human
cellular response to cytokine stimulusGO:00713451270.035
regulation of transcription from rna polymerase ii promoterGO:00063572340.034
carboxylic acid metabolic processGO:00197522890.034
hormone transportGO:00099141210.033
purine containing compound catabolic processGO:00725231380.033
histamine production involved in inflammatory responseGO:000234930.033
cellular chemical homeostasisGO:00550822470.033
single organism catabolic processGO:00447122830.032
regulation of transcription dna templatedGO:00063553740.032
anion transportGO:00068201780.032
catabolic processGO:00090563510.032
regulation of anatomical structure sizeGO:00900661350.032
cell morphogenesis involved in differentiationGO:00009041190.031
Human
regulation of rna metabolic processGO:00512523910.031
cellular homeostasisGO:00197252520.031
glycosyl compound catabolic processGO:19016581260.030
cell chemotaxisGO:0060326310.029
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.029
reproductionGO:00000032450.029
actin nucleationGO:004501020.029
reproductive processGO:00224143720.029
regulation of nucleoside metabolic processGO:0009118660.029
response to hypoxiaGO:00016662310.029
nucleic acid templated transcriptionGO:00976593790.029
organic anion transportGO:00157111320.029
barbed end actin filament cappingGO:005101610.028
proteolysisGO:00065081750.028
inflammatory responseGO:00069541500.028
purine ribonucleoside metabolic processGO:00461281680.028
nucleoside phosphate metabolic processGO:00067532830.028
generation of precursor metabolites and energyGO:0006091620.027
response to extracellular stimulusGO:00099913800.027
positive regulation of leukocyte migrationGO:0002687210.027
regulation of cell migrationGO:00303341280.027
response to electrical stimulusGO:0051602560.027
response to glucocorticoidGO:00513842230.026
muscle system processGO:00030121150.026
epithelium developmentGO:0060429960.026
Mouse
axon developmentGO:0061564960.026
organic acid metabolic processGO:00060822920.026
organelle organizationGO:00069962660.026
Human Yeast Mouse
regulation of programmed cell deathGO:00430673410.026
embryo developmentGO:0009790490.025
Mouse
regulation of protein polymerizationGO:0032271190.025
regulation of cellular localizationGO:00603412630.025
oxidation reduction processGO:00551143040.025
purine ribonucleoside monophosphate metabolic processGO:0009167840.025
cellular response to stressGO:00335542690.025
actin filament polymerizationGO:0030041110.025
regulation of actin cytoskeleton organizationGO:0032956300.025
Mouse
cellular amino acid metabolic processGO:00065201070.024
negative regulation of cell divisionGO:005178210.024
regulation of cell differentiationGO:00455953200.024
Human
actin polymerization or depolymerizationGO:0008154140.024
Yeast Mouse
peptidyl lysine acetylationGO:0018394110.024
response to peptideGO:19016522920.023
regulation of multicellular organismal developmentGO:20000263760.023
Human
ion transmembrane transportGO:00342203650.023
muscle structure developmentGO:0061061870.023
small gtpase mediated signal transductionGO:0007264360.023
regulation of phosphorus metabolic processGO:00511743490.023
regulation of anatomical structure morphogenesisGO:00226031410.023
Human
positive regulation of cellular biosynthetic processGO:00313282950.022
synaptic growth at neuromuscular junctionGO:005112410.022
aromatic compound catabolic processGO:00194391680.022
calcium ion transportGO:00068161310.022
cellular macromolecular complex assemblyGO:0034622580.022
cell activationGO:0001775970.022
protein acetylationGO:0006473110.022
striated muscle tissue developmentGO:0014706580.022
regulation of molecular functionGO:00650093980.021
cellular response to electrical stimulusGO:007125780.021
nucleobase containing small molecule metabolic processGO:00550863160.021
actin filament bundle organizationGO:0061572190.021
neuron projection morphogenesisGO:00488121220.021
Human
cell adhesionGO:00071551100.021
immune system processGO:00023762040.021
regulation of cell developmentGO:00602842630.021
Human
divalent metal ion transportGO:00708381320.020
male gamete generationGO:0048232990.020
positive regulation of developmental processGO:00510942830.020
regulation of cytoskeleton organizationGO:0051493490.020
Mouse
regulation of cell motilityGO:20001451310.020
response to oxygen levelsGO:00704822650.020
organonitrogen compound catabolic processGO:19015651790.020
nucleobase containing compound catabolic processGO:00346551520.020
regulation of leukocyte migrationGO:0002685240.020
regulation of actin filament depolymerizationGO:003083420.020
Mouse
negative regulation of cell communicationGO:00106481580.019
circulatory system developmentGO:00723591340.019
negative regulation of cellular protein metabolic processGO:00322691060.019
cation homeostasisGO:00550801950.019
nucleotide catabolic processGO:00091661390.019
purine nucleotide metabolic processGO:00061632290.019
multicellular organism reproductionGO:00325042330.019
regulation of meiotic cell cycleGO:005144530.019
cellular nitrogen compound catabolic processGO:00442701630.019
leukocyte degranulationGO:0043299120.018
regulation of actin filament based processGO:0032970420.018
Mouse
positive regulation of rna biosynthetic processGO:19026801970.018
actin filament depolymerizationGO:003004230.018
Yeast Mouse
protein transportGO:00150311320.018
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.018
angiogenesisGO:0001525530.018
ion homeostasisGO:00508012120.018
blood circulationGO:00080151830.018
purine ribonucleotide catabolic processGO:00091541360.018
single organism cell adhesionGO:0098602460.018
spermatogenesisGO:0007283990.018
regulation of peptide hormone secretionGO:0090276800.017
positive regulation of gene expressionGO:00106282440.017
cellular protein localizationGO:00346131220.017
nucleoside triphosphate catabolic processGO:00091431230.017
metal ion homeostasisGO:00550651860.017
cell migrationGO:00164771970.017
Mouse
heart contractionGO:0060047570.017
single organism reproductive processGO:00447022970.017
regulation of purine nucleotide metabolic processGO:19005421150.017
hexose transportGO:0008645290.017
organic cyclic compound catabolic processGO:19013611750.017
cellular response to insulin stimulusGO:0032869810.017
regulation of peptide secretionGO:0002791820.017
ras protein signal transductionGO:0007265290.017
positive regulation of biosynthetic processGO:00098913190.017
purine nucleoside triphosphate catabolic processGO:00091461220.017
response to other organismGO:00517072200.017
Human
cellular response to interleukin 1GO:0071347370.017
response to mechanical stimulusGO:00096121340.017
sequestering of calcium ionGO:005120880.017
nucleotide biosynthetic processGO:0009165980.017
positive regulation of endocytosisGO:0045807280.016
protein polymerizationGO:0051258220.016
gtp catabolic processGO:0006184710.016
ribonucleoside catabolic processGO:00424541260.016
regulation of insulin secretionGO:0050796650.016
production of molecular mediator involved in inflammatory responseGO:000253250.016
secretion by cellGO:00329402480.016
cell substrate adhesionGO:0031589290.016
cellular response to endogenous stimulusGO:00714953770.016
dna recombinationGO:000631030.016
oxoacid metabolic processGO:00434362900.016
muscle organ morphogenesisGO:004864410.016
neuron deathGO:00709971270.016
cardiac muscle contractionGO:0060048270.016
ribonucleotide metabolic processGO:00092592310.016
hexose metabolic processGO:0019318580.016
inorganic ion transmembrane transportGO:00986602290.016
cellular response to hormone stimulusGO:00328702470.016
regulation of cellular component biogenesisGO:0044087860.015
regulation of body fluid levelsGO:0050878900.015
gastrulationGO:000736920.015
multi organism reproductive processGO:00447032620.015
single organism cellular localizationGO:19025801020.015
histamine secretion involved in inflammatory responseGO:000244130.015
divalent inorganic cation homeostasisGO:00725071650.015
organonitrogen compound biosynthetic processGO:19015661670.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
regulation of behaviorGO:0050795610.015
cellular divalent inorganic cation homeostasisGO:00725031620.015
amine metabolic processGO:0009308380.015
striated muscle cell differentiationGO:0051146390.015
negative regulation of transportGO:00510511360.015
muscle tissue developmentGO:0060537580.015
regulation of cellular amino acid metabolic processGO:000652120.015
internal peptidyl lysine acetylationGO:001839390.015
positive regulation of phosphate metabolic processGO:00459372620.015
cardiac muscle tissue developmentGO:0048738260.015
positive regulation of transportGO:00510502450.015
regulation of hormone secretionGO:00468831060.015
multicellular organismal homeostasisGO:0048871490.015
regulation of catalytic activityGO:00507903040.015
regulation of protein heterodimerization activityGO:004349710.015
cellular catabolic processGO:00442482950.015
carbohydrate derivative catabolic processGO:19011361470.015
regulation of phosphate metabolic processGO:00192203490.015
jump responseGO:000763010.015
cellular response to nitrogen compoundGO:19016992100.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.014
arp2 3 complex mediated actin nucleationGO:003431420.014
carbohydrate derivative metabolic processGO:19011353460.014
cytokinesisGO:000091050.014
Mouse
negative regulation of arp2 3 complex mediated actin nucleationGO:003431610.014
regulation of cellular protein metabolic processGO:00322682670.014
cellular amine metabolic processGO:0044106380.014
response to hexoseGO:00097461440.014
regulation of hormone levelsGO:00108171870.014
oligodendrocyte differentiationGO:0048709320.014
regulation of ion homeostasisGO:2000021630.014
response to calcium ionGO:0051592590.014
antigen processing and presentation of peptide antigen via mhc class iGO:000247410.014
gland developmentGO:00487321550.014
purine nucleoside monophosphate catabolic processGO:0009128550.014
neuron differentiationGO:00301823680.014
Human
striated muscle contractionGO:0006941440.014
response to corticosteroidGO:00319602350.014
cation transportGO:00068123820.014
sexual reproductionGO:00199531480.014
carbohydrate biosynthetic processGO:0016051420.013
nucleoside triphosphate metabolic processGO:00091411440.013
organelle localizationGO:0051640550.013
negative regulation of homeostatic processGO:0032845470.013
epithelial cell differentiationGO:0030855710.013
transcription from rna polymerase ii promoterGO:00063662520.013
regulation of cellular component movementGO:00512701500.013
single organism carbohydrate catabolic processGO:0044724400.013
divalent inorganic cation transportGO:00725111340.013
protein localization to organelleGO:0033365570.013
negative regulation of biosynthetic processGO:00098901680.013
taxisGO:0042330670.013
cytoplasmic transportGO:00164821150.013
regulation of nucleotide metabolic processGO:00061401170.013
regulation of ion transportGO:00432692450.013
regulation of nitric oxide synthase activityGO:005099980.013
heart processGO:0003015570.013
rna localizationGO:000640340.013
positive regulation of organelle organizationGO:0010638480.013
Mouse
anatomical structure formation involved in morphogenesisGO:0048646830.013
Mouse
negative regulation of response to stimulusGO:00485851550.013
platelet aggregationGO:007052740.013
cell morphogenesisGO:00009021420.013
Human
cell agingGO:0007569140.013
regulation of homeostatic processGO:00328441010.013
ribonucleoside monophosphate metabolic processGO:0009161880.013
negative regulation of cell deathGO:00605482290.013
organophosphate catabolic processGO:00464341480.013
regulation of ion transmembrane transporter activityGO:0032412480.013
response to decreased oxygen levelsGO:00362932370.012
regulation of sequestering of calcium ionGO:0051282260.012
regulation of nucleotide catabolic processGO:0030811650.012
purine ribonucleotide metabolic processGO:00091502270.012
renal system processGO:0003014400.012
negative regulation of signal transductionGO:0009968830.012
viral gene expressionGO:001908020.012
ribonucleoside metabolic processGO:00091191740.012
axonogenesisGO:0007409710.012
camera type eye developmentGO:0043010480.012
cardiocyte differentiationGO:0035051220.012
atp metabolic processGO:0046034720.012
cellular component assembly involved in morphogenesisGO:0010927170.012
myeloid cell differentiationGO:0030099220.012
regulation of cellular catabolic processGO:00313291010.012
regulation of secretion by cellGO:19035302080.012
regulation of arp2 3 complex mediated actin nucleationGO:003431520.012
calcium ion transport into cytosolGO:0060402380.012
response to interleukin 1GO:0070555550.012
regulation of embryonic developmentGO:004599520.012
muscle cell differentiationGO:0042692520.011
positive regulation of rna metabolic processGO:00512542030.011
positive regulation of immune system processGO:0002684900.011
positive regulation of response to stimulusGO:00485842850.011
behavioral response to ethanolGO:004814910.011
behaviorGO:00076102050.011
heterocycle catabolic processGO:00467001670.011
organophosphate biosynthetic processGO:00904071430.011
striated muscle cell developmentGO:0055002260.011
regulation of actin nucleationGO:005112520.011
eye developmentGO:0001654500.011
response to caffeineGO:0031000180.011
circulatory system processGO:00030131830.011
viral transcriptionGO:001908320.011
nicotinamide nucleotide biosynthetic processGO:001935920.011
regulation of actin filament lengthGO:0030832120.011
Mouse
negative regulation of apoptotic processGO:00430661810.011
fertilizationGO:000956630.011
adult locomotory behaviorGO:000834440.011
carbohydrate metabolic processGO:00059751300.011
stress fiber assemblyGO:0043149130.011
cellular calcium ion homeostasisGO:00068741600.011
actin filament bundle assemblyGO:0051017190.011
muscle tissue morphogenesisGO:006041510.011
polysaccharide metabolic processGO:0005976250.010
muscle organ developmentGO:0007517500.010
programmed cell deathGO:00125013920.010
cellular component movementGO:00069282480.010
Mouse
positive regulation of chemotaxisGO:0050921230.010
organic acid biosynthetic processGO:0016053830.010
cell growthGO:00160491040.010
positive regulation of cellular amine metabolic processGO:003324030.010
response to metal ionGO:00100382530.010
regulation of metal ion transportGO:00109591180.010
cellular ketone metabolic processGO:0042180510.010
cell morphogenesis involved in neuron differentiationGO:00486671060.010
Human
myeloid leukocyte activationGO:0002274360.010
nucleic acid transportGO:005065730.010
negative regulation of catalytic activityGO:00430861030.010
single fertilizationGO:000733830.010
negative regulation of hydrolase activityGO:0051346520.010

Cfl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.192
disease of anatomical entityDOID:700.192
sensory system diseaseDOID:005015500.167
organ system cancerDOID:005068600.026
disease of cellular proliferationDOID:1456600.026
cancerDOID:16200.026
autosomal dominant nonsyndromic deafnessDOID:005056400.012
nonsyndromic deafnessDOID:005056300.012
auditory system diseaseDOID:274200.012