Rattus norvegicus

22 known processes

Pi4ka

phosphatidylinositol 4-kinase, catalytic, alpha

(Aliases: Pik4ca)

Pi4ka biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organophosphate metabolic processGO:00196373700.188
intracellular transportGO:00469071850.183
regulation of signal transductionGO:00099663180.166
single organism catabolic processGO:00447122830.159
carboxylic acid metabolic processGO:00197522890.143
regulation of molecular functionGO:00650093980.141
catabolic processGO:00090563510.124
oxoacid metabolic processGO:00434362900.118
regulation of transcription dna templatedGO:00063553740.117
intracellular signal transductionGO:00355563140.112
positive regulation of gene expressionGO:00106282440.109
nucleobase containing small molecule metabolic processGO:00550863160.108
rna metabolic processGO:00160704060.106
organic acid metabolic processGO:00060822920.102
purine nucleotide metabolic processGO:00061632290.101
regulation of nucleic acid templated transcriptionGO:19035063800.100
rna biosynthetic processGO:00327743800.099
carbohydrate derivative metabolic processGO:19011353460.098
protein phosphorylationGO:00064683450.094
positive regulation of phosphorus metabolic processGO:00105622620.091
positive regulation of cellular biosynthetic processGO:00313282950.087
regulation of phosphate metabolic processGO:00192203490.085
nucleoside phosphate metabolic processGO:00067532830.085
transcription dna templatedGO:00063513770.084
organelle organizationGO:00069962660.084
positive regulation of nucleobase containing compound metabolic processGO:00459353190.080
purine ribonucleotide metabolic processGO:00091502270.080
lipid metabolic processGO:00066292830.080
positive regulation of nitrogen compound metabolic processGO:00511733340.078
nucleotide metabolic processGO:00091172790.076
positive regulation of biosynthetic processGO:00098913190.075
regulation of phosphorus metabolic processGO:00511743490.075
macromolecular complex assemblyGO:00650032730.074
regulation of rna metabolic processGO:00512523910.073
organophosphate catabolic processGO:00464341480.073
single organism biosynthetic processGO:00447113420.073
carbohydrate metabolic processGO:00059751300.072
nucleic acid templated transcriptionGO:00976593790.072
ribose phosphate metabolic processGO:00196932350.072
neuronal ion channel clusteringGO:004516130.070
positive regulation of macromolecule biosynthetic processGO:00105572470.069
organonitrogen compound catabolic processGO:19015651790.069
purine nucleoside triphosphate metabolic processGO:00091441410.068
ribonucleotide metabolic processGO:00092592310.067
positive regulation of purine nucleotide metabolic processGO:1900544910.066
purine ribonucleoside catabolic processGO:00461301240.066
apoptotic processGO:00069153810.066
cellular component biogenesisGO:00440853680.065
ribonucleoside triphosphate metabolic processGO:00091991410.064
single organism organelle organizationGO:19025891800.064
cellular catabolic processGO:00442482950.063
guanosine containing compound metabolic processGO:1901068740.063
transcription from rna polymerase ii promoterGO:00063662520.059
ribonucleotide catabolic processGO:00092611360.059
regulation of rna biosynthetic processGO:20011413810.059
cellular ketone metabolic processGO:0042180510.058
positive regulation of phosphate metabolic processGO:00459372620.058
regulation of gtpase activityGO:0043087570.058
organic substance catabolic processGO:19015753160.058
programmed cell deathGO:00125013920.057
regulation of intracellular signal transductionGO:19025312180.056
purine nucleoside metabolic processGO:00422781690.056
cellular component morphogenesisGO:00329891550.056
protein autophosphorylationGO:0046777660.055
growthGO:00400071650.055
regulation of nucleotide metabolic processGO:00061401170.055
neuron differentiationGO:00301823680.055
regulation of cellular ketone metabolic processGO:0010565270.055
organic cyclic compound catabolic processGO:19013611750.055
cellular lipid metabolic processGO:00442552080.054
anatomical structure morphogenesisGO:00096532980.054
regulation of cell differentiationGO:00455953200.054
purine containing compound catabolic processGO:00725231380.054
regulation of protein phosphorylationGO:00019321830.053
nucleobase containing compound catabolic processGO:00346551520.053
aromatic compound catabolic processGO:00194391680.053
macromolecular complex subunit organizationGO:00439333390.053
nucleoside phosphate catabolic processGO:19012921400.052
glycosyl compound metabolic processGO:19016571820.051
regulation of purine nucleotide catabolic processGO:0033121650.051
nucleoside catabolic processGO:00091641260.051
organelle localizationGO:0051640550.050
establishment of organelle localizationGO:0051656370.049
regulation of cellular protein metabolic processGO:00322682670.049
purine containing compound metabolic processGO:00725212530.048
purine nucleoside triphosphate catabolic processGO:00091461220.048
reproductive processGO:00224143720.047
positive regulation of nucleoside metabolic processGO:0045979550.046
response to nutrient levelsGO:00316673700.046
cellular component movementGO:00069282480.046
regulation of multicellular organismal developmentGO:20000263760.046
nucleoside metabolic processGO:00091161790.046
regulation of purine nucleotide metabolic processGO:19005421150.046
gtp metabolic processGO:0046039720.045
synaptic vesicle endocytosisGO:004848840.045
regulation of hydrolase activityGO:00513361430.044
single organism carbohydrate metabolic processGO:00447231180.044
regulation of phosphorylationGO:00423252480.044
single organism cellular localizationGO:19025801020.043
ribonucleoside triphosphate catabolic processGO:00092031220.043
regulation of transcription from rna polymerase ii promoterGO:00063572340.043
positive regulation of transcription dna templatedGO:00458931970.042
protein complex subunit organizationGO:00718223020.042
neuron developmentGO:00486662860.042
positive regulation of nucleotide metabolic processGO:0045981910.042
glycosyl compound catabolic processGO:19016581260.041
positive regulation of rna biosynthetic processGO:19026801970.041
cellular nitrogen compound catabolic processGO:00442701630.041
positive regulation of gtpase activityGO:0043547470.040
regulation of catalytic activityGO:00507903040.040
regulation of nucleotide catabolic processGO:0030811650.040
positive regulation of molecular functionGO:00440932300.040
regulation of programmed cell deathGO:00430673410.040
ribonucleoside metabolic processGO:00091191740.040
cation transportGO:00068123820.039
central nervous system developmentGO:00074173110.039
protein oligomerizationGO:00512591910.038
response to extracellular stimulusGO:00099913800.038
single organism intracellular transportGO:19025821660.038
regulation of apoptotic processGO:00429813350.038
positive regulation of rna metabolic processGO:00512542030.038
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.038
positive regulation of nucleic acid templated transcriptionGO:19035081970.037
purine ribonucleoside metabolic processGO:00461281680.037
oxidation reduction processGO:00551143040.037
positive regulation of catalytic activityGO:00430851840.037
ras protein signal transductionGO:0007265290.037
nucleoside triphosphate catabolic processGO:00091431230.037
cellular amino acid metabolic processGO:00065201070.037
cellular component assemblyGO:00226073600.036
purine ribonucleotide catabolic processGO:00091541360.036
neuron projection developmentGO:00311752730.036
regulation of protein metabolic processGO:00512462890.036
g protein coupled receptor signaling pathwayGO:00071862420.036
purine ribonucleoside triphosphate metabolic processGO:00092051400.036
intracellular protein transportGO:0006886790.035
cell projection organizationGO:00300303020.035
positive regulation of signalingGO:00230562700.035
nucleotide catabolic processGO:00091661390.035
regulation of cellular catabolic processGO:00313291010.035
response to acid chemicalGO:00011012220.034
secretionGO:00469033070.034
cell cell signalingGO:00072673350.034
synaptic transmissionGO:00072682350.034
protein complex biogenesisGO:00702712630.033
response to corticosteroidGO:00319602350.033
organophosphate biosynthetic processGO:00904071430.033
positive regulation of cell proliferationGO:00082842490.033
cellular amine metabolic processGO:0044106380.032
positive regulation of multicellular organismal processGO:00512403870.032
positive regulation of response to stimulusGO:00485842850.032
heterocycle catabolic processGO:00467001670.032
regulation of cell proliferationGO:00421273590.032
locomotionGO:00400112370.032
reproductionGO:00000032450.031
small gtpase mediated signal transductionGO:0007264360.031
regulation of system processGO:00440572080.031
metal ion transportGO:00300012890.031
ribonucleoside catabolic processGO:00424541260.031
lipid biosynthetic processGO:00086101280.030
chemical homeostasisGO:00488782920.030
regulation of protein modification processGO:00313991940.030
negative regulation of macromolecule metabolic processGO:00106052600.029
neurological system processGO:00508772190.029
nucleoside triphosphate metabolic processGO:00091411440.029
embryonic pattern specificationGO:000988010.029
regulation of cell developmentGO:00602842630.029
positive regulation of hydrolase activityGO:0051345860.029
homeostatic processGO:00425923310.029
small molecule catabolic processGO:0044282590.028
single organism reproductive processGO:00447022970.028
positive regulation of cell differentiationGO:00455972170.028
positive regulation of gtp catabolic processGO:0033126480.028
alcohol metabolic processGO:0006066770.027
vesicle mediated transportGO:00161921810.027
positive regulation of protein phosphorylationGO:00019341350.027
regulation of cellular amino acid metabolic processGO:000652120.027
negative regulation of metabolic processGO:00098923310.027
regulation of catabolic processGO:00098941130.027
positive regulation of developmental processGO:00510942830.026
protein complex assemblyGO:00064612630.026
cellular ion homeostasisGO:00068731840.026
purine nucleoside catabolic processGO:00061521240.026
response to oxygen levelsGO:00704822650.026
monocarboxylic acid metabolic processGO:00327871520.025
protein localizationGO:00081041910.025
brain developmentGO:00074202470.025
response to hypoxiaGO:00016662310.025
cell type specific apoptotic processGO:00972851340.025
carbohydrate derivative catabolic processGO:19011361470.025
actin filament based processGO:0030029860.025
cellular response to stressGO:00335542690.025
purine nucleotide catabolic processGO:00061951360.025
positive regulation of cell communicationGO:00106472710.025
secretion by cellGO:00329402480.025
regulation of cellular component organizationGO:00511283680.024
regulation of neurogenesisGO:00507672470.024
organonitrogen compound biosynthetic processGO:19015661670.024
negative regulation of cellular metabolic processGO:00313242810.024
amine metabolic processGO:0009308380.024
regulation of ion transportGO:00432692450.024
response to peptideGO:19016522920.024
gtp catabolic processGO:0006184710.024
cellular response to hormone stimulusGO:00328702470.024
cellular response to nitrogen compoundGO:19016992100.024
blood circulationGO:00080151830.023
localization of cellGO:00516742020.023
regulation of gtp catabolic processGO:0033124580.023
response to glucocorticoidGO:00513842230.023
regulation of translationGO:0006417270.023
synaptic growth at neuromuscular junctionGO:005112410.023
cognitionGO:0050890920.022
regulation of cellular amine metabolic processGO:003323880.022
negative regulation of apoptotic processGO:00430661810.022
establishment of vesicle localizationGO:0051650310.022
divalent inorganic cation homeostasisGO:00725071650.022
regulation of nervous system developmentGO:00519602640.022
cellular divalent inorganic cation homeostasisGO:00725031620.022
ion homeostasisGO:00508012120.022
positive regulation of cellular catabolic processGO:0031331710.022
positive regulation of ras gtpase activityGO:0032320280.022
neuron deathGO:00709971270.022
multi organism reproductive processGO:00447032620.022
positive regulation of phosphorylationGO:00423271770.021
positive regulation of protein metabolic processGO:00512471780.021
positive regulation of cellular component organizationGO:00511302000.021
response to oxidative stressGO:00069791860.021
generation of precursor metabolites and energyGO:0006091620.021
peptidyl serine phosphorylationGO:0018105330.021
response to amino acidGO:0043200750.021
purine ribonucleoside triphosphate catabolic processGO:00092071220.021
agingGO:00075682410.021
positive regulation of neurogenesisGO:00507691650.021
positive regulation of protein modification processGO:00314011420.021
regulation of protein kinase activityGO:00458591050.020
cellular metal ion homeostasisGO:00068751720.020
cellular response to oxygen containing compoundGO:19017013860.020
macromolecule localizationGO:00330362520.020
response to inorganic substanceGO:00100353770.020
cellular response to endogenous stimulusGO:00714953770.020
regulation of anatomical structure sizeGO:00900661350.020
negative regulation of cell deathGO:00605482290.020
regulation of secretionGO:00510462240.020
adult locomotory behaviorGO:000834440.020
negative regulation of programmed cell deathGO:00430691830.020
cellular homeostasisGO:00197252520.020
response to nutrientGO:00075842480.020
protein transportGO:00150311320.019
membrane organizationGO:0061024940.019
negative regulation of multicellular organismal processGO:00512412030.019
response to metal ionGO:00100382530.019
actin cytoskeleton organizationGO:0030036730.019
circulatory system processGO:00030131830.019
cytoplasmic transportGO:00164821150.019
negative regulation of cell communicationGO:00106481580.019
signal releaseGO:00230611450.019
signal transduction by phosphorylationGO:00230141440.019
positive regulation of purine nucleotide catabolic processGO:0033123530.019
positive regulation of nucleotide catabolic processGO:0030813530.019
cation homeostasisGO:00550801950.019
regulation of nucleoside metabolic processGO:0009118660.019
protein heterooligomerizationGO:0051291890.019
positive regulation of cell developmentGO:00107201760.019
lipid modificationGO:0030258520.018
monovalent inorganic cation transportGO:00156721720.018
cell projection morphogenesisGO:00488581230.018
developmental process involved in reproductionGO:00030061590.018
cellular chemical homeostasisGO:00550822470.018
vesicle localizationGO:0051648330.018
learning or memoryGO:0007611900.018
cell morphogenesisGO:00009021420.018
multicellular organism growthGO:003526410.018
positive regulation of nervous system developmentGO:00519621780.017
cytoskeleton organizationGO:00070101110.017
response to ammonium ionGO:0060359710.017
inorganic cation transmembrane transportGO:00986622020.017
negative regulation of signalingGO:00230571570.017
cellular cation homeostasisGO:00300031800.017
cellular response to organonitrogen compoundGO:00714171970.017
developmental growthGO:00485891000.017
sexual reproductionGO:00199531480.017
regulation of body fluid levelsGO:0050878900.017
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296830.017
single organism carbohydrate catabolic processGO:0044724400.017
axon cargo transportGO:000808810.017
organic hydroxy compound metabolic processGO:19016151150.017
cell growthGO:00160491040.017
positive regulation of cellular amine metabolic processGO:003324030.017
negative regulation of gene expressionGO:00106291990.016
regulation of anatomical structure morphogenesisGO:00226031410.016
muscle system processGO:00030121150.016
epithelial cell differentiationGO:0030855710.016
regulation of secretion by cellGO:19035302080.016
axon developmentGO:0061564960.016
phospholipid metabolic processGO:0006644610.016
positive regulation of transportGO:00510502450.016
positive regulation of cellular protein metabolic processGO:00322701670.016
establishment of protein localizationGO:00451841410.016
response to decreased oxygen levelsGO:00362932370.016
endocytosisGO:0006897840.016
dephosphorylationGO:0016311980.016
negative regulation of cellular protein metabolic processGO:00322691060.016
multicellular organism reproductionGO:00325042330.016
developmental maturationGO:0021700250.015
response to insulinGO:00328681330.015
positive regulation of signal transductionGO:00099671750.015
cell migrationGO:00164771970.015
ion transmembrane transportGO:00342203650.015
cell motilityGO:00488702020.015
peptidyl amino acid modificationGO:00181931260.015
axis specificationGO:000979840.015
response to woundingGO:00096112540.015
negative regulation of molecular functionGO:00440921330.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
carbohydrate derivative biosynthetic processGO:19011371240.015
anterior posterior pattern specificationGO:000995210.015
peptidyl tyrosine phosphorylationGO:0018108720.015
sequestering of metal ionGO:005123890.015
regulation of cell migrationGO:00303341280.015
regulation of neuron deathGO:19012141150.015
multicellular organismal reproductive processGO:00486092330.015
response to peptide hormoneGO:00434342780.014
regulation of tube sizeGO:0035150890.014
negative regulation of cell differentiationGO:0045596990.014
cell part morphogenesisGO:00329901230.014
behaviorGO:00076102050.014
response to monosaccharideGO:00342841590.014
cellular carbohydrate metabolic processGO:0044262720.014
metal ion homeostasisGO:00550651860.014
posttranscriptional regulation of gene expressionGO:0010608370.014
calcium ion homeostasisGO:00550741620.014
single organism behaviorGO:00447081300.014
response to cytokineGO:00340972150.014
protein targetingGO:0006605610.014
regulation of muscle system processGO:0090257790.014
regulation of hormone levelsGO:00108171870.014
regulation of transferase activityGO:00513381230.014
regulation of locomotionGO:00400121480.014
gland developmentGO:00487321550.013
regulation of metal ion transportGO:00109591180.013
negative regulation of response to stimulusGO:00485851550.013
regulation of reactive oxygen species metabolic processGO:2000377260.013
response to ketoneGO:19016541820.013
embryonic axis specificationGO:000057810.013
regulation of cellular localizationGO:00603412630.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
translationGO:0006412350.013
positive regulation of cell deathGO:00109421840.013
regulation of ras gtpase activityGO:0032318320.013
cellular macromolecule localizationGO:00707271220.013
chromatin assembly or disassemblyGO:000633310.013
reactive oxygen species metabolic processGO:0072593370.013
meiotic cell cycle processGO:190304630.013
positive regulation of catabolic processGO:0009896780.013
nucleotide biosynthetic processGO:0009165980.013
positive regulation of secretionGO:00510471400.013
cellular protein localizationGO:00346131220.013
erythrocyte differentiationGO:003021810.013
regulation of synaptic transmissionGO:00508041410.013
eye morphogenesisGO:004859240.013
neuron projection morphogenesisGO:00488121220.013
sequestering of calcium ionGO:005120880.013
response to estrogenGO:00436272320.013
regulation of growthGO:00400081050.013
negative regulation of cell developmentGO:0010721820.013
calcium mediated signalingGO:0019722230.013
single organism membrane organizationGO:0044802740.013
divalent metal ion transportGO:00708381320.012
regulation of neuron projection developmentGO:00109751610.012
positive regulation of protein kinase activityGO:0045860730.012
negative regulation of protein metabolic processGO:00512481140.012
glycerolipid metabolic processGO:0046486670.012
negative regulation of neurogenesisGO:0050768780.012
positive regulation of secretion by cellGO:19035321280.012
small molecule biosynthetic processGO:00442831240.012
cell cycleGO:00070491010.012
carboxylic acid catabolic processGO:0046395490.012
cellular response to external stimulusGO:00714961180.012
tissue developmentGO:00098882520.012
regulation of kinase activityGO:00435491170.012
asymmetric protein localizationGO:000810520.012
regulation of transporter activityGO:0032409500.012
divalent inorganic cation transportGO:00725111340.012
negative regulation of innate immune responseGO:004582440.012
response to estradiolGO:00323551640.012
positive regulation of programmed cell deathGO:00430681570.012
nuclear transportGO:0051169490.012
regulation of blood circulationGO:19035221100.012
cellular calcium ion homeostasisGO:00068741600.012
reactive oxygen species biosynthetic processGO:190340980.012
neuron neuron synaptic transmissionGO:0007270600.012
neuromuscular processGO:005090520.012
synapse organizationGO:0050808460.012
synapse assemblyGO:0007416290.011
head developmentGO:00603222470.011
cellular response to lipidGO:00713962010.011
negative regulation of catalytic activityGO:00430861030.011
regulation of small gtpase mediated signal transductionGO:0051056480.011
taxisGO:0042330670.011
calcium ion transportGO:00068161310.011
regulation of neuron differentiationGO:00456642080.011
mapk cascadeGO:00001651400.011
b cell differentiationGO:003018320.011
regenerationGO:00310991630.011
neuromuscular synaptic transmissionGO:000727420.011
carbohydrate catabolic processGO:0016052400.011
nitrogen compound transportGO:00717052290.011
biological adhesionGO:00226101100.011
negative regulation of signal transductionGO:0009968830.011
response to ethanolGO:00454711620.011
sex differentiationGO:00075481130.011
rho protein signal transductionGO:0007266110.011
proteolysisGO:00065081750.011
purine ribonucleotide biosynthetic processGO:0009152810.011
regulation of neurotransmitter levelsGO:0001505420.011
muscle contractionGO:0006936880.011
cytosolic calcium ion homeostasisGO:00514801400.011
negative regulation of developmental processGO:00510931250.011
regulation of ion transmembrane transportGO:00347651210.011
forebrain developmentGO:0030900980.011
spindle organizationGO:000705120.011
chromosome segregationGO:000705920.011
nucleocytoplasmic transportGO:0006913480.011
peptidyl serine modificationGO:0018209340.011
hepaticobiliary system developmentGO:0061008900.011
regulation of cell growthGO:0001558850.011
protein maturationGO:0051604680.010
positive regulation of apoptotic processGO:00430651540.010
synaptic vesicle localizationGO:0097479240.010
cell morphogenesis involved in neuron differentiationGO:00486671060.010
cell adhesionGO:00071551100.010
smooth muscle cell proliferationGO:0048659770.010
neuron apoptotic processGO:0051402880.010
response to carbohydrateGO:00097431830.010
neurotransmitter transportGO:0006836420.010
response to growth factorGO:00708481890.010
regulation of ras protein signal transductionGO:0046578450.010
guanosine containing compound catabolic processGO:1901069710.010
negative regulation of cell proliferationGO:00082851190.010
reactive nitrogen species metabolic processGO:200105710.010
cell morphogenesis involved in differentiationGO:00009041190.010
cellular response to growth factor stimulusGO:00713631620.010
purine nucleotide biosynthetic processGO:0006164830.010

Pi4ka disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.086
nervous system diseaseDOID:86300.086
central nervous system diseaseDOID:33100.051
brain diseaseDOID:93600.051
epilepsy syndromeDOID:182600.051
electroclinical syndromeDOID:005070100.051
idiopathic generalized epilepsyDOID:182700.021
disease of metabolismDOID:001466700.017