Rattus norvegicus

17 known processes

Hlcs

holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase)

(Aliases: RGD1565360)

Hlcs biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of molecular functionGO:00650093980.055
regulation of catalytic activityGO:00507903040.051
organic acid metabolic processGO:00060822920.050
positive regulation of nitrogen compound metabolic processGO:00511733340.048
regulation of phosphorus metabolic processGO:00511743490.048
regulation of phosphate metabolic processGO:00192203490.047
intracellular signal transductionGO:00355563140.047
transcription dna templatedGO:00063513770.041
catabolic processGO:00090563510.041
central nervous system developmentGO:00074173110.041
positive regulation of phosphate metabolic processGO:00459372620.040
regulation of protein metabolic processGO:00512462890.040
oxoacid metabolic processGO:00434362900.037
nucleotide metabolic processGO:00091172790.037
nucleoside phosphate metabolic processGO:00067532830.036
positive regulation of molecular functionGO:00440932300.036
cellular response to endogenous stimulusGO:00714953770.036
positive regulation of phosphorus metabolic processGO:00105622620.035
carboxylic acid metabolic processGO:00197522890.035
cation transportGO:00068123820.035
regulation of cellular protein metabolic processGO:00322682670.034
cellular response to oxygen containing compoundGO:19017013860.034
positive regulation of catalytic activityGO:00430851840.033
nucleobase containing small molecule metabolic processGO:00550863160.033
response to extracellular stimulusGO:00099913800.033
single organism biosynthetic processGO:00447113420.032
organophosphate metabolic processGO:00196373700.032
response to corticosteroidGO:00319602350.032
aromatic compound catabolic processGO:00194391680.032
response to nutrient levelsGO:00316673700.031
response to inorganic substanceGO:00100353770.031
negative regulation of cellular metabolic processGO:00313242810.031
single organism catabolic processGO:00447122830.031
positive regulation of nucleobase containing compound metabolic processGO:00459353190.031
protein phosphorylationGO:00064683450.030
negative regulation of macromolecule metabolic processGO:00106052600.030
cellular amine metabolic processGO:0044106380.029
cellular response to nitrogen compoundGO:19016992100.029
amine metabolic processGO:0009308380.029
regulation of rna biosynthetic processGO:20011413810.029
cellular component assemblyGO:00226073600.028
proteolysisGO:00065081750.028
rna metabolic processGO:00160704060.028
multi organism reproductive processGO:00447032620.028
response to metal ionGO:00100382530.028
organelle organizationGO:00069962660.028
nucleic acid templated transcriptionGO:00976593790.028
rna biosynthetic processGO:00327743800.028
cell projection organizationGO:00300303020.028
response to nutrientGO:00075842480.028
response to acid chemicalGO:00011012220.027
positive regulation of biosynthetic processGO:00098913190.027
regulation of cellular ketone metabolic processGO:0010565270.027
purine containing compound metabolic processGO:00725212530.027
macromolecular complex subunit organizationGO:00439333390.027
cellular catabolic processGO:00442482950.027
ribose phosphate metabolic processGO:00196932350.027
purine nucleotide metabolic processGO:00061632290.026
negative regulation of metabolic processGO:00098923310.026
oxidation reduction processGO:00551143040.026
negative regulation of cell deathGO:00605482290.026
regulation of phosphorylationGO:00423252480.025
regulation of signal transductionGO:00099663180.025
heterocycle catabolic processGO:00467001670.025
ribonucleotide metabolic processGO:00092592310.025
cellular response to stressGO:00335542690.025
homeostatic processGO:00425923310.025
small gtpase mediated signal transductionGO:0007264360.025
secretionGO:00469033070.025
regulation of cell proliferationGO:00421273590.025
negative regulation of gene expressionGO:00106291990.024
nucleoside phosphate catabolic processGO:19012921400.024
positive regulation of cellular biosynthetic processGO:00313282950.024
cellular amino acid metabolic processGO:00065201070.024
apoptotic processGO:00069153810.024
regulation of rna metabolic processGO:00512523910.024
lipid metabolic processGO:00066292830.023
response to peptide hormoneGO:00434342780.023
regulation of cellular component organizationGO:00511283680.023
regulation of cellular amine metabolic processGO:003323880.023
cellular component biogenesisGO:00440853680.023
carbohydrate derivative metabolic processGO:19011353460.023
positive regulation of purine nucleotide metabolic processGO:1900544910.023
nitrogen compound transportGO:00717052290.023
ribonucleoside metabolic processGO:00091191740.023
reproductionGO:00000032450.023
purine ribonucleotide metabolic processGO:00091502270.023
positive regulation of cell communicationGO:00106472710.023
ras protein signal transductionGO:0007265290.022
organic substance catabolic processGO:19015753160.022
regulation of cellular amino acid metabolic processGO:000652120.022
glycosyl compound metabolic processGO:19016571820.022
single organism reproductive processGO:00447022970.022
regulation of catabolic processGO:00098941130.022
regulation of nucleic acid templated transcriptionGO:19035063800.021
nucleoside metabolic processGO:00091161790.021
neuron differentiationGO:00301823680.021
cellular ketone metabolic processGO:0042180510.021
purine ribonucleoside triphosphate metabolic processGO:00092051400.021
regulation of protein phosphorylationGO:00019321830.021
regulation of transcription dna templatedGO:00063553740.021
regulation of protein modification processGO:00313991940.021
cellular homeostasisGO:00197252520.021
purine nucleoside metabolic processGO:00422781690.021
organonitrogen compound catabolic processGO:19015651790.020
regulation of transcription from rna polymerase ii promoterGO:00063572340.020
anatomical structure morphogenesisGO:00096532980.020
transmembrane transportGO:00550854120.020
nucleoside catabolic processGO:00091641260.020
head developmentGO:00603222470.020
regulation of apoptotic processGO:00429813350.020
secretion by cellGO:00329402480.020
positive regulation of cellular amine metabolic processGO:003324030.019
response to peptideGO:19016522920.019
response to oxidative stressGO:00069791860.019
positive regulation of cell proliferationGO:00082842490.019
regulation of nucleotide metabolic processGO:00061401170.019
cellular nitrogen compound catabolic processGO:00442701630.019
regulation of intracellular signal transductionGO:19025312180.019
cell cell signalingGO:00072673350.019
organophosphate catabolic processGO:00464341480.019
purine ribonucleoside metabolic processGO:00461281680.019
negative regulation of biosynthetic processGO:00098901680.019
positive regulation of protein metabolic processGO:00512471780.019
transcription from rna polymerase ii promoterGO:00063662520.019
multicellular organismal reproductive processGO:00486092330.019
multicellular organism reproductionGO:00325042330.019
nucleobase containing compound catabolic processGO:00346551520.019
organic cyclic compound catabolic processGO:19013611750.019
nucleotide catabolic processGO:00091661390.018
anion transportGO:00068201780.018
regulation of programmed cell deathGO:00430673410.018
agingGO:00075682410.018
reproductive processGO:00224143720.018
protein complex subunit organizationGO:00718223020.018
ribonucleotide catabolic processGO:00092611360.018
negative regulation of programmed cell deathGO:00430691830.018
tissue developmentGO:00098882520.018
brain developmentGO:00074202470.018
programmed cell deathGO:00125013920.018
chemical homeostasisGO:00488782920.018
positive regulation of gene expressionGO:00106282440.018
glycosyl compound catabolic processGO:19016581260.018
regulation of cellular catabolic processGO:00313291010.017
response to decreased oxygen levelsGO:00362932370.017
response to growth factorGO:00708481890.017
localization of cellGO:00516742020.017
nucleoside triphosphate metabolic processGO:00091411440.017
negative regulation of apoptotic processGO:00430661810.017
regulation of purine nucleotide metabolic processGO:19005421150.017
negative regulation of macromolecule biosynthetic processGO:00105581480.017
macromolecule localizationGO:00330362520.017
purine ribonucleoside triphosphate catabolic processGO:00092071220.017
positive regulation of phosphorylationGO:00423271770.017
regulation of cellular localizationGO:00603412630.017
positive regulation of cell deathGO:00109421840.017
positive regulation of nucleotide metabolic processGO:0045981910.017
response to vitaminGO:00332731310.017
regulation of hydrolase activityGO:00513361430.017
cellular response to hormone stimulusGO:00328702470.017
negative regulation of cellular biosynthetic processGO:00313271610.017
synaptic transmissionGO:00072682350.016
organic anion transportGO:00157111320.016
neuron deathGO:00709971270.016
response to hypoxiaGO:00016662310.016
cellular response to lipidGO:00713962010.016
positive regulation of response to stimulusGO:00485842850.016
ribonucleoside catabolic processGO:00424541260.016
carbohydrate derivative catabolic processGO:19011361470.016
eye morphogenesisGO:004859240.016
positive regulation of cellular protein metabolic processGO:00322701670.016
negative regulation of cell communicationGO:00106481580.016
cellular lipid metabolic processGO:00442552080.016
regulation of ion transportGO:00432692450.016
lipid biosynthetic processGO:00086101280.016
purine ribonucleoside catabolic processGO:00461301240.016
ion transmembrane transportGO:00342203650.016
protein complex biogenesisGO:00702712630.016
neuron developmentGO:00486662860.016
negative regulation of signalingGO:00230571570.016
neuron projection developmentGO:00311752730.016
purine nucleoside triphosphate metabolic processGO:00091441410.016
response to estrogenGO:00436272320.016
gastrulationGO:000736920.015
regulation of hormone levelsGO:00108171870.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
regulation of purine nucleotide catabolic processGO:0033121650.015
small molecule biosynthetic processGO:00442831240.015
purine nucleotide catabolic processGO:00061951360.015
positive regulation of macromolecule biosynthetic processGO:00105572470.015
positive regulation of rna metabolic processGO:00512542030.015
metal ion transportGO:00300012890.015
regulation of canonical wnt signaling pathwayGO:006082840.015
positive regulation of signalingGO:00230562700.015
cellular chemical homeostasisGO:00550822470.015
ribonucleoside triphosphate metabolic processGO:00091991410.015
response to oxygen levelsGO:00704822650.015
purine containing compound catabolic processGO:00725231380.015
vesicle mediated transportGO:00161921810.015
regulation of system processGO:00440572080.014
regulation of multicellular organismal developmentGO:20000263760.014
multicellular organism growthGO:003526410.014
nucleoside triphosphate catabolic processGO:00091431230.014
cellular response to growth factor stimulusGO:00713631620.014
intracellular transportGO:00469071850.014
carbohydrate derivative biosynthetic processGO:19011371240.014
cell type specific apoptotic processGO:00972851340.014
organonitrogen compound biosynthetic processGO:19015661670.014
cell migrationGO:00164771970.014
regulation of membrane potentialGO:00423911100.014
response to mechanical stimulusGO:00096121340.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
regulation of nervous system developmentGO:00519602640.014
mapk cascadeGO:00001651400.014
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.014
regulation of cell motilityGO:20001451310.013
cellular cation homeostasisGO:00300031800.013
positive regulation of programmed cell deathGO:00430681570.013
regulation of secretionGO:00510462240.013
regulation of gtpase activityGO:0043087570.013
regulation of nucleotide catabolic processGO:0030811650.013
regulation of anatomical structure sizeGO:00900661350.013
protein complex assemblyGO:00064612630.013
positive regulation of intracellular signal transductionGO:19025331380.013
purine nucleoside triphosphate catabolic processGO:00091461220.013
cellular ion homeostasisGO:00068731840.013
response to ketoneGO:19016541820.013
positive regulation of cellular catabolic processGO:0031331710.013
ion homeostasisGO:00508012120.013
positive regulation of hydrolase activityGO:0051345860.013
response to cytokineGO:00340972150.013
response to woundingGO:00096112540.013
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
cellular response to external stimulusGO:00714961180.013
multicellular organismal signalingGO:0035637440.013
rhythmic processGO:00485111560.013
negative regulation of transportGO:00510511360.013
metal ion homeostasisGO:00550651860.013
cellular response to organonitrogen compoundGO:00714171970.013
cellular response to peptideGO:19016531330.013
macromolecular complex assemblyGO:00650032730.013
growthGO:00400071650.013
amide transportGO:00428861050.013
single organism organelle organizationGO:19025891800.013
response to glucoseGO:00097491360.013
regulation of secretion by cellGO:19035302080.013
positive regulation of nucleoside metabolic processGO:0045979550.013
positive regulation of protein phosphorylationGO:00019341350.013
negative regulation of nucleobase containing compound metabolic processGO:00459341530.013
positive regulation of ion transportGO:0043270940.013
developmental process involved in reproductionGO:00030061590.013
regulation of synaptic transmissionGO:00508041410.012
regulation of neuron deathGO:19012141150.012
protein localizationGO:00081041910.012
positive regulation of protein modification processGO:00314011420.012
regulation of cell developmentGO:00602842630.012
positive regulation of transportGO:00510502450.012
locomotionGO:00400112370.012
divalent inorganic cation homeostasisGO:00725071650.012
purine ribonucleotide catabolic processGO:00091541360.012
carbohydrate metabolic processGO:00059751300.012
inorganic ion transmembrane transportGO:00986602290.012
sexual reproductionGO:00199531480.012
neurological system processGO:00508772190.012
positive regulation of purine nucleotide catabolic processGO:0033123530.012
cellular component movementGO:00069282480.012
single organism intracellular transportGO:19025821660.012
positive regulation of nucleotide catabolic processGO:0030813530.012
lipid storageGO:001991510.012
cell motilityGO:00488702020.012
positive regulation of developmental processGO:00510942830.012
response to monosaccharideGO:00342841590.012
axis specificationGO:000979840.012
regulation of proteasomal protein catabolic processGO:006113640.012
regulation of cell differentiationGO:00455953200.012
regulation of nucleoside metabolic processGO:0009118660.012
regulation of cell projection organizationGO:00313441750.012
positive regulation of apoptotic processGO:00430651540.012
cell growthGO:00160491040.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
protein oligomerizationGO:00512591910.012
negative regulation of rna metabolic processGO:00512531230.012
purine nucleoside catabolic processGO:00061521240.012
response to ethanolGO:00454711620.012
regulation of cell growthGO:0001558850.012
organophosphate biosynthetic processGO:00904071430.012
positive regulation of transcription dna templatedGO:00458931970.011
negative regulation of nucleic acid templated transcriptionGO:19035071170.011
regulation of kinase activityGO:00435491170.011
negative regulation of multicellular organismal processGO:00512412030.011
positive regulation of rna biosynthetic processGO:19026801970.011
organic acid transportGO:00158491160.011
cellular component morphogenesisGO:00329891550.011
carboxylic acid transportGO:00469421150.011
positive regulation of secretion by cellGO:19035321280.011
positive regulation of multicellular organismal processGO:00512403870.011
response to glucocorticoidGO:00513842230.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
negative regulation of protein metabolic processGO:00512481140.011
response to hexoseGO:00097461440.011
transmission of nerve impulseGO:0019226420.011
monovalent inorganic cation transportGO:00156721720.011
positive regulation of signal transductionGO:00099671750.011
behaviorGO:00076102050.011
rho protein signal transductionGO:0007266110.011
regulation of cellular component movementGO:00512701500.011
positive regulation of cellular component organizationGO:00511302000.011
developmental growthGO:00485891000.011
negative regulation of cellular protein metabolic processGO:00322691060.011
cell morphogenesis involved in differentiationGO:00009041190.011
cation homeostasisGO:00550801950.011
gland developmentGO:00487321550.011
cardiovascular system developmentGO:00723581340.011
regulation of transferase activityGO:00513381230.011
circulatory system developmentGO:00723591340.011
positive regulation of nervous system developmentGO:00519621780.011
male gamete generationGO:0048232990.011
response to toxic substanceGO:00096361330.011
hormone transportGO:00099141210.011
response to transition metal nanoparticleGO:19902671220.011
neuromuscular processGO:005090520.011
forebrain developmentGO:0030900980.011
monocarboxylic acid metabolic processGO:00327871520.011
heart morphogenesisGO:000300730.011
response to purine containing compoundGO:00140741260.011
divalent metal ion transportGO:00708381320.011
cellular divalent inorganic cation homeostasisGO:00725031620.011
response to carbohydrateGO:00097431830.011
single organism carbohydrate metabolic processGO:00447231180.011
sex differentiationGO:00075481130.011
negative regulation of rna biosynthetic processGO:19026791180.011
adult locomotory behaviorGO:000834440.011
signal transduction by phosphorylationGO:00230141440.011
regulation of growthGO:00400081050.010
positive regulation of gtp catabolic processGO:0033126480.010
reproductive structure developmentGO:00486081280.010
reactive oxygen species biosynthetic processGO:190340980.010
muscle structure developmentGO:0061061870.010
organic hydroxy compound transportGO:0015850770.010
positive regulation of cell developmentGO:00107201760.010
organic acid biosynthetic processGO:0016053830.010
cellular response to peptide hormone stimulusGO:00713751200.010
peptide transportGO:0015833970.010
camera type eye morphogenesisGO:004859320.010
inorganic cation transmembrane transportGO:00986622020.010
regulation of neurogenesisGO:00507672470.010

Hlcs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.022
nervous system diseaseDOID:86300.022
disease of metabolismDOID:001466700.021
inherited metabolic disorderDOID:65500.014
musculoskeletal system diseaseDOID:1700.013
sensory system diseaseDOID:005015500.011