IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Col15a1

collagen, type XV, alpha 1

Entrez: 298069
Ensembl: ENSRNOG00000039197
RGD: 1310820

Process Predictions
Disease Predictions

Col15a1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
response to inorganic substance	GO:0010035	377	0.311	Rat
cellular response to peptide	GO:1901653	133	0.287
cellular response to endogenous stimulus	GO:0071495	377	0.284
cellular response to hormone stimulus	GO:0032870	247	0.283
cellular response to vitamin e	GO:0071306	3	0.215
cellular response to peptide hormone stimulus	GO:0071375	120	0.193
response to fluoride	GO:1902617	3	0.189
response to ionizing radiation	GO:0010212	59	0.157
response to purine containing compound	GO:0014074	126	0.147
endochondral bone growth	GO:0003416	3	0.143
response to oxygen levels	GO:0070482	265	0.136
cell motility	GO:0048870	202	0.133
tissue development	GO:0009888	252	0.130
response to nutrient levels	GO:0031667	370	0.119
embryonic skeletal system development	GO:0048706	3	0.116
striated muscle tissue development	GO:0014706	58	0.115
endochondral bone morphogenesis	GO:0060350	7	0.114
macromolecular complex subunit organization	GO:0043933	339	0.099
muscle organ development	GO:0007517	50	0.097
cellular response to nitrogen compound	GO:1901699	210	0.093
immune system process	GO:0002376	204	0.092
cartilage development involved in endochondral bone morphogenesis	GO:0060351	3	0.090
cellular response to nicotine	GO:0071316	7	0.090
muscle tissue development	GO:0060537	58	0.089
extracellular fibril organization	GO:0043206	1	0.087
response to radiation	GO:0009314	137	0.086
response to interleukin 2	GO:0070669	1	0.086
protein complex subunit organization	GO:0071822	302	0.085
response to wounding	GO:0009611	254	0.081
response to hypoxia	GO:0001666	231	0.081
response to hyperoxia	GO:0055093	45	0.081
regulation of signal transduction	GO:0009966	318	0.080
response to nutrient	GO:0007584	248	0.078
response to extracellular stimulus	GO:0009991	380	0.078
organ morphogenesis	GO:0009887	75	0.076
skin morphogenesis	GO:0043589	2	0.074
blood circulation	GO:0008015	183	0.072
growth plate cartilage development	GO:0003417	2	0.067
response to vitamin e	GO:0033197	24	0.066
cellular component assembly	GO:0022607	360	0.066
cellular response to oxygen containing compound	GO:1901701	386	0.065
wound healing	GO:0042060	122	0.064
female pregnancy	GO:0007565	122	0.063
muscle structure development	GO:0061061	87	0.062
cellular component biogenesis	GO:0044085	368	0.062
protein complex assembly	GO:0006461	263	0.062
protein oligomerization	GO:0051259	191	0.060
transcription dna templated	GO:0006351	377	0.058
anatomical structure morphogenesis	GO:0009653	298	0.056
response to oxidative stress	GO:0006979	186	0.055
response to retinoic acid	GO:0032526	63	0.054
cellular response to organonitrogen compound	GO:0071417	197	0.053
response to tumor necrosis factor	GO:0034612	56	0.053
response to camp	GO:0051591	91	0.052
tissue remodeling	GO:0048771	40	0.052
multi organism reproductive process	GO:0044703	262	0.051
protein complex biogenesis	GO:0070271	263	0.049
response to insulin	GO:0032868	133	0.049
response to mechanical stimulus	GO:0009612	134	0.048
cellular response to low density lipoprotein particle stimulus	GO:0071404	3	0.047
cellular amino acid metabolic process	GO:0006520	107	0.047
collagen fibril organization	GO:0030199	1	0.047
regulation of immune system process	GO:0002682	123	0.047
response to transforming growth factor beta	GO:0071559	46	0.046
response to metal ion	GO:0010038	253	0.045
epiboly involved in wound healing	GO:0090505	2	0.044
macromolecular complex assembly	GO:0065003	273	0.044
cation transmembrane transport	GO:0098655	263	0.044
response to increased oxygen levels	GO:0036296	45	0.042
cation transport	GO:0006812	382	0.042
vesicle mediated transport	GO:0016192	181	0.042
response to fibroblast growth factor	GO:0071774	29	0.042
skeletal system morphogenesis	GO:0048705	12	0.041
cartilage development	GO:0051216	22	0.041
regulation of leukocyte migration	GO:0002685	24	0.041
cellular response to lipid	GO:0071396	201	0.041
regulation of rna metabolic process	GO:0051252	391	0.040
response to estrogen	GO:0043627	232	0.040
renal system development	GO:0072001	67	0.040
regulation of rna biosynthetic process	GO:2001141	381	0.039
regulation of transcription dna templated	GO:0006355	374	0.039
ras protein signal transduction	GO:0007265	29	0.039
response to nicotine	GO:0035094	51	0.039
regulation of nucleic acid templated transcription	GO:1903506	380	0.039
response to peptide	GO:1901652	292	0.039
extracellular structure organization	GO:0043062	13	0.038
positive regulation of transport	GO:0051050	245	0.038
cellular response to mechanical stimulus	GO:0071260	48	0.038
response to organophosphorus	GO:0046683	102	0.038
circulatory system process	GO:0003013	183	0.038
cellular response to organic cyclic compound	GO:0071407	202	0.036
transcription from rna polymerase ii promoter	GO:0006366	252	0.036
reproductive process	GO:0022414	372	0.036
rna metabolic process	GO:0016070	406	0.036
response to vitamin	GO:0033273	131	0.036
negative regulation of cellular biosynthetic process	GO:0031327	161	0.036
locomotion	GO:0040011	237	0.035
kidney development	GO:0001822	67	0.034
macromolecule localization	GO:0033036	252	0.033
endocytosis	GO:0006897	84	0.033
positive regulation of developmental process	GO:0051094	283	0.033
positive regulation of cellular amine metabolic process	GO:0033240	3	0.033
cellular component movement	GO:0006928	248	0.033
epithelial cell proliferation	GO:0050673	54	0.032
response to norepinephrine	GO:0071873	5	0.031
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.030
response to x ray	GO:0010165	15	0.030
formation of primary germ layer	GO:0001704	1	0.030
negative regulation of cellular metabolic process	GO:0031324	281	0.029
protein phosphorylation	GO:0006468	345	0.029
regulation of multicellular organismal development	GO:2000026	376	0.029
response to acid chemical	GO:0001101	222	0.028	Rat
artery development	GO:0060840	3	0.028
regulation of canonical wnt signaling pathway	GO:0060828	4	0.028
negative regulation of immune system process	GO:0002683	39	0.028
regulation of cell differentiation	GO:0045595	320	0.028
response to catecholamine	GO:0071869	16	0.027
head development	GO:0060322	247	0.027
organ growth	GO:0035265	24	0.027
eye morphogenesis	GO:0048592	4	0.027
epiboly	GO:0090504	2	0.027
localization of cell	GO:0051674	202	0.027
skeletal muscle organ development	GO:0060538	33	0.027
skin development	GO:0043588	17	0.027
gastrulation	GO:0007369	2	0.026
chemical homeostasis	GO:0048878	292	0.026
eye development	GO:0001654	50	0.026
intracellular signal transduction	GO:0035556	314	0.026
regulation of metal ion transport	GO:0010959	118	0.026
peptidyl amino acid modification	GO:0018193	126	0.026
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.026
multi multicellular organism process	GO:0044706	138	0.025
transmembrane transport	GO:0055085	412	0.025
skeletal system development	GO:0001501	41	0.025
nucleic acid templated transcription	GO:0097659	379	0.024
cellular response to external stimulus	GO:0071496	118	0.024
response to low density lipoprotein particle	GO:0055098	4	0.024
response to growth factor	GO:0070848	189	0.024
peptide cross linking	GO:0018149	1	0.024
wound healing spreading of cells	GO:0044319	2	0.023
skeletal muscle tissue development	GO:0007519	31	0.023
response to corticosteroid	GO:0031960	235	0.023
multicellular organism reproduction	GO:0032504	233	0.023
response to external biotic stimulus	GO:0043207	221	0.023
immune response	GO:0006955	104	0.023
homeostatic process	GO:0042592	331	0.023
rna biosynthetic process	GO:0032774	380	0.023
growth	GO:0040007	165	0.022
insulin like growth factor receptor signaling pathway	GO:0048009	3	0.022
negative regulation of organ growth	GO:0046621	3	0.022
cellular response to transforming growth factor beta stimulus	GO:0071560	41	0.021
odontogenesis	GO:0042476	32	0.021
regulation of cellular amine metabolic process	GO:0033238	8	0.021
regulation of cellular amino acid metabolic process	GO:0006521	2	0.021
cellular response to cytokine stimulus	GO:0071345	127	0.021
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.021
negative regulation of innate immune response	GO:0045824	4	0.021
negative regulation of heart growth	GO:0061117	3	0.021
cellular response to tumor necrosis factor	GO:0071356	46	0.021
negative regulation of multicellular organismal process	GO:0051241	203	0.021
multicellular organismal catabolic process	GO:0044243	2	0.021
metal ion transport	GO:0030001	289	0.020
cellular amine metabolic process	GO:0044106	38	0.020
inorganic cation transmembrane transport	GO:0098662	202	0.020
regulation of cellular component organization	GO:0051128	368	0.020
ossification	GO:0001503	70	0.020
regulation of apoptotic process	GO:0042981	335	0.019
positive regulation of cell proliferation	GO:0008284	249	0.019
positive regulation of phosphate metabolic process	GO:0045937	262	0.019
mast cell chemotaxis	GO:0002551	4	0.019
actin filament based movement	GO:0030048	16	0.019
cellular response to growth factor stimulus	GO:0071363	162	0.019
catabolic process	GO:0009056	351	0.019
negative regulation of macromolecule metabolic process	GO:0010605	260	0.019
multicellular organismal macromolecule metabolic process	GO:0044259	21	0.019
cellular ketone metabolic process	GO:0042180	51	0.019
blood vessel morphogenesis	GO:0048514	58	0.019
collagen metabolic process	GO:0032963	21	0.018
negative regulation of metabolic process	GO:0009892	331	0.018
cellular response to nutrient	GO:0031670	30	0.018
cellular response to abiotic stimulus	GO:0071214	85	0.018
cellular homeostasis	GO:0019725	252	0.018
organic substance catabolic process	GO:1901575	316	0.018
regulation of epithelial cell proliferation	GO:0050678	49	0.018
extracellular matrix organization	GO:0030198	13	0.018
response to peptide hormone	GO:0043434	278	0.017
regulation of blood pressure	GO:0008217	83	0.017
amine metabolic process	GO:0009308	38	0.017
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.017
response to glucose	GO:0009749	136	0.017
oxoacid metabolic process	GO:0043436	290	0.017
negative regulation of programmed cell death	GO:0043069	183	0.017
regulation of anatomical structure morphogenesis	GO:0022603	141	0.017
tube development	GO:0035295	89	0.017
positive regulation of leukocyte migration	GO:0002687	21	0.017
response to ketone	GO:1901654	182	0.017
aging	GO:0007568	241	0.017
cell morphogenesis	GO:0000902	142	0.017
embryonic skeletal system morphogenesis	GO:0048704	3	0.017
bone development	GO:0060348	25	0.017
response to estradiol	GO:0032355	164	0.017
connective tissue development	GO:0061448	33	0.016
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.016
cell projection organization	GO:0030030	302	0.016
multicellular organismal reproductive process	GO:0048609	233	0.016
negative regulation of biosynthetic process	GO:0009890	168	0.016
cellular macromolecule localization	GO:0070727	122	0.016
developmental growth	GO:0048589	100	0.016
camera type eye morphogenesis	GO:0048593	2	0.016
regulation of stem cell differentiation	GO:2000736	2	0.016
response to monosaccharide	GO:0034284	159	0.016
positive regulation of cell communication	GO:0010647	271	0.016
brain development	GO:0007420	247	0.015
intracellular transport	GO:0046907	185	0.015
response to transition metal nanoparticle	GO:1990267	122	0.015
regulation of ion transport	GO:0043269	245	0.015
regulation of vesicle mediated transport	GO:0060627	81	0.015
cellular response to nutrient levels	GO:0031669	60	0.015
type b pancreatic cell proliferation	GO:0044342	3	0.015
proteolysis	GO:0006508	175	0.015
regulation of defense response	GO:0031347	68	0.015
regulation of phosphate metabolic process	GO:0019220	349	0.015
limb morphogenesis	GO:0035108	4	0.015
peptidyl lysine hydroxylation	GO:0017185	1	0.015
positive regulation of rna biosynthetic process	GO:1902680	197	0.015
cellular response to stress	GO:0033554	269	0.015
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.015
cardiac ventricle development	GO:0003231	1	0.014
negative regulation of response to stimulus	GO:0048585	155	0.014
regulation of membrane potential	GO:0042391	110	0.014
negative regulation of cardiac muscle tissue growth	GO:0055022	3	0.014
hindlimb morphogenesis	GO:0035137	2	0.014
response to alkaloid	GO:0043279	132	0.014
positive regulation of synaptic plasticity	GO:0031915	3	0.014
monovalent inorganic cation transport	GO:0015672	172	0.014
cellular response to alkaloid	GO:0071312	25	0.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	2	0.014
positive regulation of gene expression	GO:0010628	244	0.014
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.014
aorta development	GO:0035904	2	0.014
secretion	GO:0046903	307	0.014
central nervous system development	GO:0007417	311	0.013
vasculature development	GO:0001944	70	0.013
response to hydrogen peroxide	GO:0042542	89	0.013
regulation of cellular ketone metabolic process	GO:0010565	27	0.013
receptor mediated endocytosis	GO:0006898	42	0.013
cellular response to iron iii ion	GO:0071283	3	0.013
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.013
male sex differentiation	GO:0046661	64	0.013
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	GO:0010880	4	0.013
single organism biosynthetic process	GO:0044711	342	0.013
regulation of embryonic development	GO:0045995	2	0.013
development of primary sexual characteristics	GO:0045137	107	0.013
tooth eruption	GO:0044691	1	0.013
positive regulation of cell differentiation	GO:0045597	217	0.013
organelle organization	GO:0006996	266	0.013
inflammatory response	GO:0006954	150	0.013
wound healing spreading of epidermal cells	GO:0035313	2	0.013
development of primary female sexual characteristics	GO:0046545	56	0.013
regulation of ossification	GO:0030278	32	0.013
protein localization	GO:0008104	191	0.012
cellular response to insulin stimulus	GO:0032869	81	0.012
positive regulation of protein phosphorylation	GO:0001934	135	0.012
cellular cation homeostasis	GO:0030003	180	0.012
cardiac muscle cell contraction	GO:0086003	10	0.012
cellular response to interleukin 2	GO:0071352	1	0.012
sequestering of metal ion	GO:0051238	9	0.012
regulation of cell motility	GO:2000145	131	0.012
protein heterotrimerization	GO:0070208	2	0.012
sensory perception	GO:0007600	101	0.012
regulation of cell growth	GO:0001558	85	0.012
response to ethanol	GO:0045471	162	0.012
cellular chemical homeostasis	GO:0055082	247	0.012
cellular response to extracellular stimulus	GO:0031668	73	0.012
cellular response to acid chemical	GO:0071229	75	0.012
gonad development	GO:0008406	104	0.012
epithelium development	GO:0060429	96	0.012
response to bacterium	GO:0009617	200	0.012
small gtpase mediated signal transduction	GO:0007264	36	0.012
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.012
cellular response to fluoride	GO:1902618	1	0.012
developmental process involved in reproduction	GO:0003006	159	0.012
embryonic cranial skeleton morphogenesis	GO:0048701	2	0.012
sex differentiation	GO:0007548	113	0.011
positive regulation of response to stimulus	GO:0048584	285	0.011
neuron projection development	GO:0031175	273	0.011
cellular response to epidermal growth factor stimulus	GO:0071364	12	0.011
negative regulation of cell communication	GO:0010648	158	0.011
regulation of epithelial to mesenchymal transition	GO:0010717	2	0.011
organophosphate catabolic process	GO:0046434	148	0.011
neural crest cell development	GO:0014032	2	0.011
negative regulation of transforming growth factor beta receptor signaling pathway	GO:0030512	2	0.011
regulation of cell morphogenesis	GO:0022604	77	0.011
sequestering of calcium ion	GO:0051208	8	0.011
urogenital system development	GO:0001655	78	0.011
regulation of endocytosis	GO:0030100	42	0.011
positive regulation of secretion	GO:0051047	140	0.011
single organism intracellular transport	GO:1902582	166	0.011
positive regulation of molecular function	GO:0044093	230	0.011
negative regulation of homeostatic process	GO:0032845	47	0.011
negative regulation of apoptotic process	GO:0043066	181	0.011
negative regulation of cardiac muscle tissue development	GO:0055026	3	0.011
ion homeostasis	GO:0050801	212	0.011
tissue regeneration	GO:0042246	36	0.011
regulation of cytokine secretion	GO:0050707	11	0.011
positive regulation of epithelial cell proliferation	GO:0050679	32	0.011
regulation of immune response	GO:0050776	55	0.011
cellular response to vitamin	GO:0071295	21	0.011
renin secretion into blood stream	GO:0002001	1	0.011
dephosphorylation	GO:0016311	98	0.011
regulation of cell development	GO:0060284	263	0.011
salivary gland development	GO:0007431	3	0.011
regulation of intracellular signal transduction	GO:1902531	218	0.011
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.011
embryo development	GO:0009790	49	0.010
positive regulation of immune system process	GO:0002684	90	0.010
regulation of phosphorus metabolic process	GO:0051174	349	0.010
circulatory system development	GO:0072359	134	0.010
response to amino acid	GO:0043200	75	0.010
response to epidermal growth factor	GO:0070849	18	0.010
response to carbohydrate	GO:0009743	183	0.010
response to reactive oxygen species	GO:0000302	120	0.010
response to molecule of bacterial origin	GO:0002237	194	0.010
cell migration	GO:0016477	197	0.010
male gonad development	GO:0008584	59	0.010
positive regulation of protein modification process	GO:0031401	142	0.010
regulation of skeletal muscle tissue regeneration	GO:0043416	2	0.010
smooth muscle cell proliferation	GO:0048659	77	0.010
carbohydrate derivative metabolic process	GO:1901135	346	0.010
regulation of protein modification process	GO:0031399	194	0.010
vascular process in circulatory system	GO:0003018	96	0.010
apoptotic process	GO:0006915	381	0.010

Col15a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.115
disease of anatomical entity	DOID:7	0.115
connective tissue disease	DOID:65	0.029
nervous system disease	DOID:863	0.028
central nervous system disease	DOID:331	0.022
muscular disease	DOID:0080000	0.020
muscular dystrophy	DOID:9884	0.020
muscle tissue disease	DOID:66	0.020
myopathy	DOID:423	0.020
ehlers danlos syndrome	DOID:13359	0.016
collagen disease	DOID:854	0.016
bone development disease	DOID:0080006	0.015
osteochondrodysplasia	DOID:2256	0.015
bone disease	DOID:0080001	0.015

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