Rattus norvegicus

0 known processes

Klra22

killer cell lectin-like receptor subfamily A, member 22

(Aliases: Ly49,Ly49s2,Klra1)

Klra22 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of natural killer cell mediated immunityGO:000271640.147
Rat
negative regulation of natural killer cell mediated immune response to tumor cellGO:000285610.130
Rat
negative regulation of chronic inflammatory responseGO:000267720.127
natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000242010.108
Rat
cellular component biogenesisGO:00440853680.103
protein heterooligomerizationGO:0051291890.100
response to biotic stimulusGO:00096072260.092
Rat
synaptic transmissionGO:00072682350.089
cellular amine metabolic processGO:0044106380.086
protein transportGO:00150311320.074
monovalent inorganic cation transportGO:00156721720.072
response to inorganic substanceGO:00100353770.064
Rat
cation transportGO:00068123820.062
immune system processGO:00023762040.061
Rat
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.060
Rat
response to external biotic stimulusGO:00432072210.058
inorganic cation transmembrane transportGO:00986622020.057
cellular metal ion homeostasisGO:00068751720.055
regulation of natural killer cell mediated immune response to tumor cellGO:000285510.055
Rat
amine metabolic processGO:0009308380.053
cognitionGO:0050890920.053
negative regulation of response to tumor cellGO:000283520.050
Rat
cellular component assemblyGO:00226073600.049
negative regulation of cellular metabolic processGO:00313242810.049
head developmentGO:00603222470.048
leukocyte activationGO:0045321760.048
Rat
organophosphate metabolic processGO:00196373700.045
cellular amino acid metabolic processGO:00065201070.045
negative regulation of innate immune responseGO:004582440.045
Rat
male mating behaviorGO:006017930.045
negative regulation of long term synaptic potentiationGO:190027210.044
response to bacteriumGO:00096172000.043
small molecule catabolic processGO:0044282590.042
response to cocaineGO:0042220390.042
brain developmentGO:00074202470.042
protein phosphorylationGO:00064683450.041
regulation of membrane potentialGO:00423911100.040
rna metabolic processGO:00160704060.039
learning or memoryGO:0007611900.039
metal ion transportGO:00300012890.038
cellular ion homeostasisGO:00068731840.037
response to amineGO:0014075460.036
regulation of rna biosynthetic processGO:20011413810.036
protein complex subunit organizationGO:00718223020.036
response to amphetamineGO:0001975250.035
negative regulation of macromolecule metabolic processGO:00106052600.035
protein localizationGO:00081041910.035
sodium ion transportGO:0006814820.035
immune responseGO:00069551040.035
Rat
natural killer cell mediated immune response to tumor cellGO:000242310.034
Rat
central nervous system developmentGO:00074173110.033
neuron neuron synaptic transmissionGO:0007270600.033
regulation of cellular amino acid metabolic processGO:000652120.033
regulation of signal transductionGO:00099663180.032
response to radiationGO:00093141370.032
angioblast cell migrationGO:003547610.032
defense responseGO:00069521940.032
Rat
chronic inflammatory response to non antigenic stimulusGO:000254510.032
regulation of cellular amine metabolic processGO:003323880.032
positive regulation of developmental processGO:00510942830.031
regulation of synaptic transmissionGO:00508041410.031
negative regulation of immune system processGO:0002683390.030
Rat
positive regulation of neurogenesisGO:00507691650.030
eosinophil migrationGO:007267730.030
positive regulation of cellular amine metabolic processGO:003324030.030
blood vessel developmentGO:0001568690.029
positive regulation of response to stimulusGO:00485842850.029
anatomical structure morphogenesisGO:00096532980.029
protein oligomerizationGO:00512591910.029
nucleic acid templated transcriptionGO:00976593790.029
metanephric tubule morphogenesisGO:007217320.028
single organism catabolic processGO:00447122830.028
regulation of catabolic processGO:00098941130.028
nucleobase containing small molecule metabolic processGO:00550863160.028
neurological system processGO:00508772190.028
regulation of system processGO:00440572080.027
nitrogen compound transportGO:00717052290.027
aromatic compound catabolic processGO:00194391680.027
organic cyclic compound catabolic processGO:19013611750.027
negative regulation of protein metabolic processGO:00512481140.027
regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285810.026
Rat
regulation of cellular protein metabolic processGO:00322682670.026
nucleoside phosphate metabolic processGO:00067532830.026
neutrophil apoptotic processGO:000178140.026
regulation of metal ion transportGO:00109591180.025
positive regulation of cell proliferationGO:00082842490.025
lymphocyte chemotaxisGO:004824730.025
macromolecular complex assemblyGO:00650032730.025
organic hydroxy compound transportGO:0015850770.024
secretion by cellGO:00329402480.024
behaviorGO:00076102050.024
negative regulation of chronic inflammatory response to non antigenic stimulusGO:000288110.024
positive regulation of phosphorus metabolic processGO:00105622620.023
organelle organizationGO:00069962660.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
response to tumor cellGO:000234740.023
Rat
regulation of chronic inflammatory response to non antigenic stimulusGO:000288010.023
negative regulation of metabolic processGO:00098923310.023
glycosyl compound metabolic processGO:19016571820.023
macromolecular complex subunit organizationGO:00439333390.023
cellular ketone metabolic processGO:0042180510.023
regulation of immune responseGO:0050776550.023
Rat
regulation of cellular localizationGO:00603412630.022
positive regulation of transportGO:00510502450.022
cellular catabolic processGO:00442482950.022
ion homeostasisGO:00508012120.022
transcription dna templatedGO:00063513770.022
regulation of neuronal synaptic plasticityGO:0048168310.022
positive regulation of cellular component organizationGO:00511302000.022
t cell chemotaxisGO:001081820.022
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285910.022
Rat
regulation of immune system processGO:00026821230.022
Rat
catabolic processGO:00090563510.021
regulation of kinase activityGO:00435491170.021
negative regulation of neutrophil apoptotic processGO:003303030.020
heart processGO:0003015570.020
regulation of cellular component movementGO:00512701500.019
regulation of catalytic activityGO:00507903040.019
regulation of defense responseGO:0031347680.019
Rat
purine nucleotide metabolic processGO:00061632290.019
regulation of molecular functionGO:00650093980.019
negative regulation of molecular functionGO:00440921330.019
negative regulation of nucleobase containing compound metabolic processGO:00459341530.019
regulation of nucleic acid templated transcriptionGO:19035063800.018
regulation of neurogenesisGO:00507672470.018
regulation of anatomical structure morphogenesisGO:00226031410.018
protein complex assemblyGO:00064612630.018
sensory perception of painGO:0019233730.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
phospholipid metabolic processGO:0006644610.018
regulation of phosphorus metabolic processGO:00511743490.018
response to ammonium ionGO:0060359710.018
peptide hormone secretionGO:0030072840.018
mast cell chemotaxisGO:000255140.018
positive regulation of nitrogen compound metabolic processGO:00511733340.018
phosphatidylinositol dephosphorylationGO:004685640.017
oxoacid metabolic processGO:00434362900.017
regulation of vasculature developmentGO:1901342440.017
purine ribonucleoside metabolic processGO:00461281680.017
negative regulation of cellular protein metabolic processGO:00322691060.017
transmembrane transportGO:00550854120.017
sodium ion transmembrane transportGO:0035725670.017
regulation of neutrophil apoptotic processGO:003302940.017
establishment of protein localizationGO:00451841410.017
negative regulation of immune response to tumor cellGO:000283820.017
Rat
regulation of long term synaptic potentiationGO:190027150.017
circulatory system developmentGO:00723591340.017
establishment of vesicle localizationGO:0051650310.017
circadian rhythmGO:0007623880.016
regulation of cellular ketone metabolic processGO:0010565270.016
positive regulation of cell activationGO:0050867340.016
tissue remodelingGO:0048771400.016
positive regulation of cell developmentGO:00107201760.016
cell cell signalingGO:00072673350.016
regulation of t cell activationGO:0050863230.016
ribonucleotide metabolic processGO:00092592310.016
ribose phosphate metabolic processGO:00196932350.016
regulation of cell differentiationGO:00455953200.016
organic acid metabolic processGO:00060822920.016
regulation of phosphatidylinositol dephosphorylationGO:006030410.016
positive regulation of neuron projection developmentGO:0010976990.016
membrane depolarizationGO:0051899320.016
regulation of nervous system developmentGO:00519602640.016
positive regulation of neuron differentiationGO:00456661260.016
negative regulation of catalytic activityGO:00430861030.016
homeostatic processGO:00425923310.016
regulation of peptide secretionGO:0002791820.016
learningGO:0007612330.016
carboxylic acid metabolic processGO:00197522890.015
regulation of immune response to tumor cellGO:000283730.015
Rat
intracellular signal transductionGO:00355563140.015
regulation of nucleotide metabolic processGO:00061401170.015
response to hypoxiaGO:00016662310.015
transmission of nerve impulseGO:0019226420.015
transcription from rna polymerase ii promoterGO:00063662520.015
organonitrogen compound biosynthetic processGO:19015661670.015
regulation of postsynaptic membrane potentialGO:0060078250.015
telencephalon developmentGO:0021537620.015
signal releaseGO:00230611450.015
regulation of secretion by cellGO:19035302080.015
synaptic growth at neuromuscular junctionGO:005112410.015
cardiovascular system developmentGO:00723581340.015
positive regulation of biosynthetic processGO:00098913190.015
positive regulation of phosphorylationGO:00423271770.015
leukocyte cell cell adhesionGO:000715940.014
Rat
neuronal action potentialGO:0019228350.014
response to starvationGO:0042594590.014
positive regulation of immune system processGO:0002684900.014
purine ribonucleotide metabolic processGO:00091502270.014
positive regulation of catalytic activityGO:00430851840.014
mast cell migrationGO:009753140.014
nucleotide metabolic processGO:00091172790.014
regulation of protein metabolic processGO:00512462890.014
response to toxic substanceGO:00096361330.014
glycosyl compound catabolic processGO:19016581260.014
regulation of protein modification processGO:00313991940.014
positive regulation of hydrolase activityGO:0051345860.014
single organism behaviorGO:00447081300.014
muscle system processGO:00030121150.014
protein complex biogenesisGO:00702712630.013
synaptic transmission glutamatergicGO:0035249330.013
tumor necrosis factor biosynthetic processGO:004253310.013
purine nucleoside metabolic processGO:00422781690.013
rna biosynthetic processGO:00327743800.013
negative regulation of transcription dna templatedGO:00458921160.013
cell activationGO:0001775970.013
Rat
ion transmembrane transportGO:00342203650.013
positive regulation of cellular catabolic processGO:0031331710.013
regulation of excitatory postsynaptic membrane potentialGO:0060079180.013
positive regulation of nervous system developmentGO:00519621780.013
positive regulation of phosphate metabolic processGO:00459372620.013
positive regulation of cell differentiationGO:00455972170.013
sensory perceptionGO:00076001010.013
regulation of chronic inflammatory responseGO:000267630.013
organ formationGO:004864530.012
cellular protein localizationGO:00346131220.012
lymphocyte activationGO:0046649430.012
Rat
positive regulation of gene expressionGO:00106282440.012
jak stat cascadeGO:0007259260.012
cytokine productionGO:0001816610.012
metal ion homeostasisGO:00550651860.012
lymphocyte migrationGO:007267630.012
cellular divalent inorganic cation homeostasisGO:00725031620.012
dendrite developmentGO:0016358720.012
regulation of transcription dna templatedGO:00063553740.012
cytosolic calcium ion homeostasisGO:00514801400.012
positive regulation of rna metabolic processGO:00512542030.012
cellular component movementGO:00069282480.012
divalent metal ion transportGO:00708381320.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
ribonucleoside metabolic processGO:00091191740.012
protein secretionGO:0009306340.012
sexual reproductionGO:00199531480.011
reproductive processGO:00224143720.011
organophosphate catabolic processGO:00464341480.011
innate immune responseGO:0045087350.011
Rat
synaptic transmission glycinergicGO:006001220.011
inflammatory response to antigenic stimulusGO:0002437180.011
cellular chemical homeostasisGO:00550822470.011
eosinophil chemotaxisGO:004824530.011
multicellular organismal signalingGO:0035637440.011
regulation of response to stressGO:00801341260.011
Rat
g protein coupled receptor signaling pathwayGO:00071862420.011
regulation of immunoglobulin productionGO:000263740.011
regulation of cellular component organizationGO:00511283680.011
divalent inorganic cation homeostasisGO:00725071650.011
purine nucleotide catabolic processGO:00061951360.011
organophosphate biosynthetic processGO:00904071430.011
positive regulation of multicellular organismal processGO:00512403870.011
organic substance catabolic processGO:19015753160.011
negative regulation of protein modification processGO:0031400520.010
calcium mediated signalingGO:0019722230.010
calcium ion homeostasisGO:00550741620.010
regulation of innate immune responseGO:0045088150.010
Rat
macromolecule localizationGO:00330362520.010
purine nucleoside triphosphate catabolic processGO:00091461220.010
regulation of phosphate metabolic processGO:00192203490.010
regulation of ion transportGO:00432692450.010
regulation of multicellular organismal developmentGO:20000263760.010
positive regulation of renin secretion into blood streamGO:190013510.010
negative regulation of response to external stimulusGO:0032102370.010
neurotransmitter gated ion channel clusteringGO:007257830.010
cellular response to oxidative stressGO:0034599760.010
regulation of intracellular transportGO:0032386650.010
purine containing compound metabolic processGO:00725212530.010
cartilage condensationGO:000150220.010
positive regulation of nucleobase containing compound metabolic processGO:00459353190.010

Klra22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.050
nervous system diseaseDOID:86300.050
central nervous system diseaseDOID:33100.012
musculoskeletal system diseaseDOID:1700.011
eye and adnexa diseaseDOID:149200.011
retinal diseaseDOID:567900.011
retinal degenerationDOID:846600.011
sensory system diseaseDOID:005015500.011
eye diseaseDOID:561400.011