Rattus norvegicus

0 known processes

Lrfn2

leucine rich repeat and fibronectin type III domain containing 2

Lrfn2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of nucleobase containing compound metabolic processGO:00459341530.195
regulation of cell proliferationGO:00421273590.191
organic acid transportGO:00158491160.165
cellular chemical homeostasisGO:00550822470.163
rhythmic processGO:00485111560.159
synaptic transmissionGO:00072682350.151
positive regulation of signalingGO:00230562700.139
metal ion homeostasisGO:00550651860.137
organic hydroxy compound metabolic processGO:19016151150.134
homeostatic processGO:00425923310.132
negative regulation of gene expressionGO:00106291990.130
cell cell signalingGO:00072673350.128
regulation of behaviorGO:0050795610.121
response to glucocorticoidGO:00513842230.120
positive regulation of transportGO:00510502450.120
response to corticosteroidGO:00319602350.115
single organism reproductive processGO:00447022970.114
cation transportGO:00068123820.113
multicellular organismal reproductive processGO:00486092330.112
divalent inorganic cation homeostasisGO:00725071650.106
negative regulation of cellular biosynthetic processGO:00313271610.105
nucleic acid templated transcriptionGO:00976593790.104
cellular component movementGO:00069282480.104
multi organism reproductive processGO:00447032620.103
negative regulation of nitrogen compound metabolic processGO:00511721610.101
taxisGO:0042330670.101
behaviorGO:00076102050.100
negative regulation of cellular metabolic processGO:00313242810.099
cation homeostasisGO:00550801950.096
organic anion transportGO:00157111320.094
response to extracellular stimulusGO:00099913800.093
anatomical structure morphogenesisGO:00096532980.092
head developmentGO:00603222470.091
ion homeostasisGO:00508012120.090
programmed cell deathGO:00125013920.090
transcription from rna polymerase ii promoterGO:00063662520.090
reproductionGO:00000032450.090
cell projection organizationGO:00300303020.089
glutamate receptor signaling pathwayGO:0007215430.089
reproductive processGO:00224143720.089
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.088
regulation of cellular component organizationGO:00511283680.086
regulation of locomotionGO:00400121480.085
calcium ion homeostasisGO:00550741620.082
positive regulation of response to stimulusGO:00485842850.082
neuron differentiationGO:00301823680.081
locomotionGO:00400112370.081
multicellular organism reproductionGO:00325042330.081
negative regulation of metabolic processGO:00098923310.081
rna biosynthetic processGO:00327743800.081
cytosolic calcium ion homeostasisGO:00514801400.078
regulation of signal transductionGO:00099663180.077
regulation of rna biosynthetic processGO:20011413810.077
positive regulation of locomotionGO:00400171020.077
carboxylic acid transportGO:00469421150.077
cellular calcium ion homeostasisGO:00068741600.076
response to nutrient levelsGO:00316673700.075
response to peptideGO:19016522920.073
cation transmembrane transportGO:00986552630.072
cell projection morphogenesisGO:00488581230.069
regulation of excitatory postsynaptic membrane potentialGO:0060079180.069
chemical homeostasisGO:00488782920.069
organic substance catabolic processGO:19015753160.067
response to peptide hormoneGO:00434342780.067
cellular homeostasisGO:00197252520.066
response to growth factorGO:00708481890.064
regulation of nucleic acid templated transcriptionGO:19035063800.064
transmembrane transportGO:00550854120.064
receptor localization to synapseGO:009712020.064
macromolecule localizationGO:00330362520.063
positive regulation of nitrogen compound metabolic processGO:00511733340.063
negative regulation of biosynthetic processGO:00098901680.063
negative regulation of phosphorus metabolic processGO:0010563800.063
cellular ion homeostasisGO:00068731840.062
response to starvationGO:0042594590.062
sexual reproductionGO:00199531480.062
protein complex subunit organizationGO:00718223020.062
lipid metabolic processGO:00066292830.062
regulation of rna metabolic processGO:00512523910.061
response to lipopolysaccharideGO:00324961910.061
reproductive system developmentGO:00614581280.060
regulation of hormone secretionGO:00468831060.058
catabolic processGO:00090563510.056
g protein coupled receptor signaling pathwayGO:00071862420.056
inorganic cation transmembrane transportGO:00986622020.056
cell motilityGO:00488702020.055
regulation of programmed cell deathGO:00430673410.054
calcium ion transportGO:00068161310.054
amino acid transportGO:0006865700.054
cell part morphogenesisGO:00329901230.053
positive regulation of transcription dna templatedGO:00458931970.052
regulation of postsynaptic membrane potentialGO:0060078250.051
positive regulation of nucleic acid templated transcriptionGO:19035081970.051
neurological system processGO:00508772190.051
organelle organizationGO:00069962660.051
response to amineGO:0014075460.050
peptide secretionGO:0002790860.050
cellular response to oxygen containing compoundGO:19017013860.050
cellular response to endogenous stimulusGO:00714953770.050
central nervous system developmentGO:00074173110.050
response to molecule of bacterial originGO:00022371940.049
regulation of glutamate receptor signaling pathwayGO:1900449170.049
cellular response to lipidGO:00713962010.049
secretionGO:00469033070.048
response to estradiolGO:00323551640.048
positive regulation of gene expressionGO:00106282440.048
negative regulation of macromolecule metabolic processGO:00106052600.048
positive regulation of cellular component movementGO:00512721020.047
positive regulation of cell proliferationGO:00082842490.047
positive regulation of cytosolic calcium ion concentrationGO:00072041220.047
nitrogen compound transportGO:00717052290.047
purine containing compound metabolic processGO:00725212530.047
regulation of chemotaxisGO:0050920290.047
transcription dna templatedGO:00063513770.047
negative regulation of cell deathGO:00605482290.046
cellular cation homeostasisGO:00300031800.046
action potentialGO:0001508540.046
positive regulation of macromolecule biosynthetic processGO:00105572470.046
response to external biotic stimulusGO:00432072210.046
negative regulation of multicellular organismal processGO:00512412030.045
positive regulation of cell migrationGO:0030335960.044
glycerolipid metabolic processGO:0046486670.044
regulation of catalytic activityGO:00507903040.044
regulation of secretion by cellGO:19035302080.044
cell morphogenesis involved in differentiationGO:00009041190.043
positive regulation of rna metabolic processGO:00512542030.043
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.043
regulation of intracellular signal transductionGO:19025312180.043
negative regulation of nucleic acid templated transcriptionGO:19035071170.043
positive regulation of biosynthetic processGO:00098913190.042
negative regulation of rna biosynthetic processGO:19026791180.042
organophosphate metabolic processGO:00196373700.042
response to fungicideGO:0060992200.042
male mating behaviorGO:006017930.042
nucleotide metabolic processGO:00091172790.042
regulation of neurogenesisGO:00507672470.042
positive regulation of rna biosynthetic processGO:19026801970.041
positive regulation of cell communicationGO:00106472710.041
establishment of tissue polarityGO:000716420.041
erk1 and erk2 cascadeGO:0070371480.041
regulation of hormone levelsGO:00108171870.041
negative regulation of cellular component organizationGO:0051129830.041
response to acid chemicalGO:00011012220.041
anion transportGO:00068201780.040
multi multicellular organism processGO:00447061380.040
positive regulation of phosphorus metabolic processGO:00105622620.040
regulation of cell motilityGO:20001451310.039
cellular lipid metabolic processGO:00442552080.039
tube developmentGO:0035295890.038
regulation of synaptic transmissionGO:00508041410.038
positive regulation of protein metabolic processGO:00512471780.038
metal ion transportGO:00300012890.038
positive regulation of cellular component organizationGO:00511302000.038
cell migrationGO:00164771970.037
enzyme linked receptor protein signaling pathwayGO:00071671160.037
negative regulation of transcription dna templatedGO:00458921160.037
positive regulation of multicellular organismal processGO:00512403870.036
sensory perception of painGO:0019233730.036
ovulation cycle processGO:0022602500.036
neuron projection morphogenesisGO:00488121220.036
endocytosisGO:0006897840.036
regulation of apoptotic processGO:00429813350.035
regulation of peptide hormone secretionGO:0090276800.035
axonogenesisGO:0007409710.035
forebrain developmentGO:0030900980.035
negative regulation of transportGO:00510511360.035
cellular divalent inorganic cation homeostasisGO:00725031620.035
intracellular signal transductionGO:00355563140.035
positive regulation of apoptotic processGO:00430651540.035
negative regulation of programmed cell deathGO:00430691830.034
response to vitaminGO:00332731310.033
cellular response to external stimulusGO:00714961180.033
negative regulation of apoptotic processGO:00430661810.033
cellular response to organic cyclic compoundGO:00714072020.033
single organism behaviorGO:00447081300.033
mapk cascadeGO:00001651400.033
cellular response to hormone stimulusGO:00328702470.033
phospholipid metabolic processGO:0006644610.032
response to biotic stimulusGO:00096072260.032
regulation of transcription dna templatedGO:00063553740.032
positive regulation of nucleobase containing compound metabolic processGO:00459353190.032
regulation of hydrolase activityGO:00513361430.032
nucleobase containing small molecule metabolic processGO:00550863160.032
regulation of phosphate metabolic processGO:00192203490.031
regulation of ion transportGO:00432692450.031
developmental process involved in reproductionGO:00030061590.031
dephosphorylationGO:0016311980.031
smooth muscle cell proliferationGO:0048659770.031
establishment of planar polarityGO:000173610.031
response to oxygen levelsGO:00704822650.031
localization of cellGO:00516742020.031
response to woundingGO:00096112540.030
positive regulation of phosphate metabolic processGO:00459372620.030
inorganic ion transmembrane transportGO:00986602290.030
ribose phosphate metabolic processGO:00196932350.029
response to insulinGO:00328681330.029
cell morphogenesis involved in neuron differentiationGO:00486671060.029
negative regulation of secretionGO:0051048820.029
cellular response to alcoholGO:0097306870.029
positive regulation of intracellular signal transductionGO:19025331380.028
dendrite developmentGO:0016358720.028
positive regulation of ion transportGO:0043270940.028
regulation of peptide transportGO:0090087870.028
chemotaxisGO:0006935660.028
cellular response to acid chemicalGO:0071229750.028
negative regulation of rna metabolic processGO:00512531230.028
neuron projection developmentGO:00311752730.028
regulation of transcription from rna polymerase ii promoterGO:00063572340.028
cellular metal ion homeostasisGO:00068751720.027
regulation of smooth muscle cell proliferationGO:0048660750.027
positive regulation of secretion by cellGO:19035321280.027
brain developmentGO:00074202470.027
response to estrogenGO:00436272320.027
single organism organelle organizationGO:19025891800.027
hormone secretionGO:00468791150.027
peptide transportGO:0015833970.027
ion transmembrane transportGO:00342203650.026
cell morphogenesisGO:00009021420.026
vesicle mediated transportGO:00161921810.026
response to cocaineGO:0042220390.026
macromolecular complex subunit organizationGO:00439333390.025
purine nucleotide metabolic processGO:00061632290.025
response to other organismGO:00517072200.025
telencephalon developmentGO:0021537620.025
cellular response to nitrogen compoundGO:19016992100.025
anterior posterior pattern specificationGO:000995210.025
cellular ketone metabolic processGO:0042180510.024
positive regulation of signal transductionGO:00099671750.024
ribonucleotide metabolic processGO:00092592310.024
positive regulation of developmental processGO:00510942830.024
apoptotic processGO:00069153810.024
response to nutrientGO:00075842480.024
signal transduction by phosphorylationGO:00230141440.024
divalent metal ion transportGO:00708381320.024
acid secretionGO:0046717480.024
detection of visible lightGO:000958430.024
cellular response to stressGO:00335542690.024
cellular amine metabolic processGO:0044106380.024
ameboidal type cell migrationGO:0001667260.023
rna metabolic processGO:00160704060.023
response to carbohydrateGO:00097431830.023
regulation of cell migrationGO:00303341280.023
jak stat cascadeGO:0007259260.023
negative regulation of phosphate metabolic processGO:0045936800.023
cellular component assemblyGO:00226073600.023
positive regulation of cell motilityGO:2000147970.023
morphogenesis of a polarized epitheliumGO:000173810.023
reproductive structure developmentGO:00486081280.023
response to toxic substanceGO:00096361330.022
neurotransmitter gated ion channel clusteringGO:007257830.022
cellular response to abiotic stimulusGO:0071214850.022
immune system processGO:00023762040.022
sex differentiationGO:00075481130.022
peptide hormone secretionGO:0030072840.021
amide transportGO:00428861050.021
axis specificationGO:000979840.021
circadian rhythmGO:0007623880.021
negative regulation of nervous system developmentGO:0051961790.021
regulation of anatomical structure sizeGO:00900661350.021
positive regulation of secretionGO:00510471400.021
cyclic nucleotide metabolic processGO:0009187800.021
development of primary sexual characteristicsGO:00451371070.021
response to ethanolGO:00454711620.021
tissue developmentGO:00098882520.021
nucleoside phosphate metabolic processGO:00067532830.021
hormone transportGO:00099141210.021
regulation of mapk cascadeGO:00434081160.021
positive regulation of protein phosphorylationGO:00019341350.021
regulation of membrane potentialGO:00423911100.021
regulation of organic acid transportGO:0032890350.021
membrane depolarizationGO:0051899320.021
sensory perceptionGO:00076001010.020
regulation of peptide secretionGO:0002791820.020
cellular response to growth factor stimulusGO:00713631620.020
cell fate commitment involved in pattern specificationGO:006058120.020
regulation of lipid metabolic processGO:0019216680.020
amine metabolic processGO:0009308380.020
startle responseGO:000196420.020
calcium ion transmembrane transportGO:0070588700.020
lipid biosynthetic processGO:00086101280.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.019
negative regulation of neuron differentiationGO:0045665620.019
cell growthGO:00160491040.019
regulation of cell projection organizationGO:00313441750.019
gonad developmentGO:00084061040.019
positive regulation of neurogenesisGO:00507691650.019
regulation of phosphorylationGO:00423252480.019
actin cytoskeleton organizationGO:0030036730.019
regulation of n methyl d aspartate selective glutamate receptor activityGO:200031060.019
sensory organ developmentGO:0007423740.019
regulation of vesicle mediated transportGO:0060627810.019
regulation of cellular amine metabolic processGO:003323880.018
regulation of transmembrane transportGO:00347621220.018
positive regulation of neuron differentiationGO:00456661260.018
axon developmentGO:0061564960.018
neuron developmentGO:00486662860.018
gamete generationGO:00072761240.018
actin filament organizationGO:0007015420.018
organophosphate biosynthetic processGO:00904071430.018
cellular component biogenesisGO:00440853680.018
proteolysisGO:00065081750.018
embryonic pattern specificationGO:000988010.018
actin filament based processGO:0030029860.018
regulation of anatomical structure morphogenesisGO:00226031410.018
regulation of endocytosisGO:0030100420.018
cardiovascular system developmentGO:00723581340.018
regulation of phosphorus metabolic processGO:00511743490.018
protein catabolic processGO:0030163300.018
small molecule biosynthetic processGO:00442831240.018
positive regulation of nervous system developmentGO:00519621780.018
cellular response to cytokine stimulusGO:00713451270.018
regulation of multicellular organismal developmentGO:20000263760.018
cellular component morphogenesisGO:00329891550.018
cellular amino acid metabolic processGO:00065201070.018
regulation of cellular localizationGO:00603412630.017
adult locomotory behaviorGO:000834440.017
regulation of neuron differentiationGO:00456642080.017
regulation of neuron projection developmentGO:00109751610.017
development of primary female sexual characteristicsGO:0046545560.017
cellular response to metal ionGO:0071248550.017
gastrulationGO:000736920.017
alcohol metabolic processGO:0006066770.017
divalent inorganic cation transportGO:00725111340.017
positive regulation of hormone secretionGO:0046887650.017
regulation of cell differentiationGO:00455953200.017
response to light stimulusGO:0009416520.017
cellular nitrogen compound catabolic processGO:00442701630.017
organonitrogen compound biosynthetic processGO:19015661670.017
regulation of cellular amino acid metabolic processGO:000652120.017
regulation of cellular component biogenesisGO:0044087860.017
response to hypoxiaGO:00016662310.016
negative regulation of cell proliferationGO:00082851190.016
renal system processGO:0003014400.016
response to decreased oxygen levelsGO:00362932370.016
regulation of organelle organizationGO:0033043800.016
regulation of cellular component movementGO:00512701500.016
regulation of receptor activityGO:0010469290.016
single organism intracellular transportGO:19025821660.016
agingGO:00075682410.016
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.016
positive regulation of membrane potentialGO:0045838160.016
single organism biosynthetic processGO:00447113420.016
dendritic spine morphogenesisGO:006099790.016
limbic system developmentGO:0021761380.015
positive regulation of cellular amine metabolic processGO:003324030.015
response to glucoseGO:00097491360.015
regulation of neuron deathGO:19012141150.015
asymmetric protein localizationGO:000810520.015
ovulation cycleGO:0042698670.015
regulation of ion transmembrane transportGO:00347651210.015
glycerophospholipid metabolic processGO:0006650470.015
monovalent inorganic cation transportGO:00156721720.015
regulation of response to external stimulusGO:00321011060.015
negative regulation of macromolecule biosynthetic processGO:00105581480.015
smooth muscle cell migrationGO:0014909360.015
dendrite morphogenesisGO:0048813430.015
protein phosphorylationGO:00064683450.015
neuronal ion channel clusteringGO:004516130.015
neuromuscular synaptic transmissionGO:000727420.015
multicellular organism growthGO:003526410.015
regulation of growthGO:00400081050.015
regulation of nervous system developmentGO:00519602640.015
epithelium developmentGO:0060429960.015
positive regulation of endocytosisGO:0045807280.014
growthGO:00400071650.014
negative regulation of catalytic activityGO:00430861030.014
regulation of molecular functionGO:00650093980.014
regulation of kinase activityGO:00435491170.014
glutamate secretionGO:0014047190.014
camp biosynthetic processGO:0006171470.014
ionotropic glutamate receptor signaling pathwayGO:0035235340.014
positive regulation of excitatory postsynaptic membrane potentialGO:200046370.014
cellular response to organonitrogen compoundGO:00714171970.014
response to cytokineGO:00340972150.014
positive regulation of cell differentiationGO:00455972170.014
embryo developmentGO:0009790490.014
cellular response to estradiol stimulusGO:0071392160.014
cellular response to extracellular stimulusGO:0031668730.014
single organism catabolic processGO:00447122830.014
cellular catabolic processGO:00442482950.014
positive regulation of cellular protein metabolic processGO:00322701670.014
regulation of cell growthGO:0001558850.014
positive regulation of cell deathGO:00109421840.013
negative regulation of response to stimulusGO:00485851550.013
response to bacteriumGO:00096172000.013
cgmp biosynthetic processGO:0006182150.013
small molecule catabolic processGO:0044282590.013
cytoskeleton organizationGO:00070101110.013
regulation of jak stat cascadeGO:0046425210.013
signal releaseGO:00230611450.013
phosphatidylinositol dephosphorylationGO:004685640.013
positive regulation of cell projection organizationGO:00313461110.013
regulation of blood pressureGO:0008217830.013
secretion by cellGO:00329402480.013
regulation of catabolic processGO:00098941130.013
activation of protein kinase activityGO:0032147470.013
male sex differentiationGO:0046661640.013
female pregnancyGO:00075651220.013
response to transition metal nanoparticleGO:19902671220.013
positive regulation of chemotaxisGO:0050921230.013
response to ketoneGO:19016541820.013
regulation of cellular ketone metabolic processGO:0010565270.013
vascular process in circulatory systemGO:0003018960.013
membrane organizationGO:0061024940.013
cellular response to steroid hormone stimulusGO:0071383930.013
negative regulation of cell developmentGO:0010721820.013
neuron projection extensionGO:1990138260.013
response to inorganic substanceGO:00100353770.013
positive regulation of cellular biosynthetic processGO:00313282950.013
positive regulation of cellular amino acid metabolic processGO:004576410.012
negative regulation of growthGO:0045926370.012
response to ammonium ionGO:0060359710.012
nucleoside phosphate biosynthetic processGO:19012931020.012
response to morphineGO:0043278270.012
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711320.012
regulation of blood vessel sizeGO:0050880890.012
response to amphetamineGO:0001975250.012
negative regulation of receptor internalizationGO:000209120.012
regulation of receptor mediated endocytosisGO:0048259170.012
response to osmotic stressGO:0006970420.012
protein localizationGO:00081041910.012
regulation of homeostatic processGO:00328441010.012
urinary tract smooth muscle contractionGO:001484840.012
positive regulation of molecular functionGO:00440932300.012
circadian sleep wake cycleGO:0042745230.012
peristalsisGO:003043220.012
positive regulation of behaviorGO:0048520380.012
carbohydrate derivative metabolic processGO:19011353460.012
circulatory system developmentGO:00723591340.012
lymphocyte activationGO:0046649430.012
embryonic axis specificationGO:000057810.012
positive regulation of catalytic activityGO:00430851840.012
carbohydrate derivative biosynthetic processGO:19011371240.012
potassium ion transportGO:0006813970.011
chemosensory behaviorGO:000763520.011
purine ribonucleotide metabolic processGO:00091502270.011
cyclic nucleotide biosynthetic processGO:0009190630.011
positive regulation of ossificationGO:0045778170.011
response to metal ionGO:00100382530.011
female sex differentiationGO:0046660590.011
negative regulation of amino acid transportGO:0051956130.011
regulation of systemic arterial blood pressureGO:0003073300.011
neuron projection guidanceGO:0097485240.011
regulation of purine nucleotide metabolic processGO:19005421150.011
carbohydrate homeostasisGO:0033500750.011
regulation of neuronal synaptic plasticityGO:0048168310.011
regulation of body fluid levelsGO:0050878900.011
l glutamate importGO:005193820.011
receptor metabolic processGO:0043112180.011
circulatory system processGO:00030131830.011
positive regulation of phosphorylationGO:00423271770.011
negative regulation of protein phosphorylationGO:0001933440.011
salivary gland developmentGO:000743130.011
regulation of transporter activityGO:0032409500.011
leukocyte migrationGO:0050900380.011
motor neuron axon guidanceGO:000804510.011
carbohydrate derivative catabolic processGO:19011361470.011
negative regulation of neurogenesisGO:0050768780.011
muscle cell proliferationGO:0033002840.011
negative regulation of organic acid transportGO:0032891140.011
grooming behaviorGO:000762540.011
micturitionGO:006007340.011
positive regulation of programmed cell deathGO:00430681570.011
regulation of notch signaling pathwayGO:000859330.011
negative regulation of signalingGO:00230571570.011
regulation of cell morphogenesisGO:0022604770.011
dicarboxylic acid transportGO:0006835340.011
negative regulation of molecular functionGO:00440921330.011
dna metabolic processGO:0006259960.011
aromatic compound catabolic processGO:00194391680.011
ribonucleotide biosynthetic processGO:0009260850.011
response to radiationGO:00093141370.011
response to isoquinoline alkaloidGO:0014072280.010
regulation of establishment of planar polarityGO:009017520.010
cellular process involved in reproduction in multicellular organismGO:0022412350.010
regulation of insulin secretionGO:0050796650.010
spindle organizationGO:000705120.010
learning or memoryGO:0007611900.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
positive regulation of response to external stimulusGO:0032103510.010
regulation of cell sizeGO:0008361370.010
feeding behaviorGO:0007631530.010
dendritic spine organizationGO:0097061120.010
negative regulation of protein metabolic processGO:00512481140.010
response to monosaccharideGO:00342841590.010
organic hydroxy compound biosynthetic processGO:1901617510.010
regulation of cellular component sizeGO:0032535510.010
spermatogenesisGO:0007283990.010
lens fiber cell differentiationGO:007030630.010
regulation of amino acid transportGO:0051955250.010

Lrfn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.022
disease of anatomical entityDOID:700.022
sensory system diseaseDOID:005015500.022
eye and adnexa diseaseDOID:149200.016
eye diseaseDOID:561400.016