Rattus norvegicus

37 known processes

Shank3

SH3 and multiple ankyrin repeat domains 3

(Aliases: Prosap2)

Shank3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of proteasomal protein catabolic processGO:006113640.379
organophosphate catabolic processGO:00464341480.326
catabolic processGO:00090563510.182
intracellular signal transductionGO:00355563140.158
Mouse
synapse organizationGO:0050808460.152
Mouse Rat
cellular component biogenesisGO:00440853680.126
cellular catabolic processGO:00442482950.124
regulation of cellular catabolic processGO:00313291010.111
organic substance catabolic processGO:19015753160.106
regulation of catabolic processGO:00098941130.096
cellular component assemblyGO:00226073600.093
regulation of molecular functionGO:00650093980.091
Mouse
protein complex assemblyGO:00064612630.087
regulation of cellular protein metabolic processGO:00322682670.084
protein localizationGO:00081041910.084
Mouse
small gtpase mediated signal transductionGO:0007264360.072
organophosphate metabolic processGO:00196373700.070
nucleobase containing small molecule metabolic processGO:00550863160.068
protein complex biogenesisGO:00702712630.068
regulation of signal transductionGO:00099663180.063
nucleoside phosphate catabolic processGO:19012921400.062
regulation of rna biosynthetic processGO:20011413810.059
regulation of rna metabolic processGO:00512523910.056
regulation of protein metabolic processGO:00512462890.052
purine ribonucleotide catabolic processGO:00091541360.052
nucleotide metabolic processGO:00091172790.050
regulation of synaptic growth at neuromuscular junctionGO:000858210.050
aromatic compound catabolic processGO:00194391680.049
purine nucleotide metabolic processGO:00061632290.048
cellular nitrogen compound catabolic processGO:00442701630.048
ras protein signal transductionGO:0007265290.046
regulation of cellular localizationGO:00603412630.046
positive regulation of nitrogen compound metabolic processGO:00511733340.046
axis specificationGO:000979840.046
macromolecule localizationGO:00330362520.045
Mouse
cellular macromolecule localizationGO:00707271220.045
Mouse
synaptic growth at neuromuscular junctionGO:005112410.045
purine containing compound metabolic processGO:00725212530.043
programmed cell deathGO:00125013920.042
regulation of purine nucleotide metabolic processGO:19005421150.042
positive regulation of multicellular organismal processGO:00512403870.042
Mouse Rat
nucleoside phosphate metabolic processGO:00067532830.041
lipid metabolic processGO:00066292830.041
regulation of cellular component organizationGO:00511283680.041
Mouse Rat
transcription dna templatedGO:00063513770.040
cell projection organizationGO:00300303020.040
Mouse Rat
rna biosynthetic processGO:00327743800.040
protein complex subunit organizationGO:00718223020.039
ribonucleotide metabolic processGO:00092592310.039
regulation of nervous system developmentGO:00519602640.038
Mouse Rat
neuron projection developmentGO:00311752730.037
Mouse Rat
regulation of cell developmentGO:00602842630.036
Mouse Rat
organic cyclic compound catabolic processGO:19013611750.035
regulation of phosphorus metabolic processGO:00511743490.035
purine nucleotide catabolic processGO:00061951360.035
nucleobase containing compound catabolic processGO:00346551520.035
regulation of transcription from rna polymerase ii promoterGO:00063572340.035
regulation of nucleic acid templated transcriptionGO:19035063800.034
ribose phosphate metabolic processGO:00196932350.034
brain developmentGO:00074202470.033
Mouse Rat
purine containing compound catabolic processGO:00725231380.032
ion transmembrane transportGO:00342203650.032
Mouse
regulation of catalytic activityGO:00507903040.032
regulation of small gtpase mediated signal transductionGO:0051056480.031
regulation of cell projection organizationGO:00313441750.031
Mouse Rat
response to potassium ionGO:003586490.031
ribonucleotide catabolic processGO:00092611360.031
rna metabolic processGO:00160704060.031
organic acid metabolic processGO:00060822920.031
regulation of cellular amino acid metabolic processGO:000652120.030
heterocycle catabolic processGO:00467001670.030
nucleic acid templated transcriptionGO:00976593790.030
purine ribonucleoside catabolic processGO:00461301240.030
regulation of neuron projection developmentGO:00109751610.030
Mouse Rat
purine ribonucleoside triphosphate metabolic processGO:00092051400.030
purine ribonucleotide metabolic processGO:00091502270.029
transmembrane transportGO:00550854120.029
Mouse
hematopoietic progenitor cell differentiationGO:000224420.029
protein phosphorylationGO:00064683450.029
organonitrogen compound catabolic processGO:19015651790.028
regulation of glutamate receptor signaling pathwayGO:1900449170.028
cell adhesionGO:00071551100.028
nucleoside metabolic processGO:00091161790.028
regulation of gtpase activityGO:0043087570.028
single organism biosynthetic processGO:00447113420.027
neuron differentiationGO:00301823680.027
Mouse Rat
cellular amino acid metabolic processGO:00065201070.026
proteolysisGO:00065081750.026
positive regulation of gene expressionGO:00106282440.026
regulation of intracellular signal transductionGO:19025312180.025
regulation of multicellular organismal developmentGO:20000263760.025
Mouse Rat
cell projection morphogenesisGO:00488581230.025
Mouse
positive regulation of neuron projection developmentGO:0010976990.025
Mouse Rat
negative regulation of cell communicationGO:00106481580.025
Mouse
carbohydrate derivative metabolic processGO:19011353460.024
ribonucleoside triphosphate catabolic processGO:00092031220.024
transcription from rna polymerase ii promoterGO:00063662520.024
biological adhesionGO:00226101100.024
positive regulation of synapse maturationGO:009012920.024
positive regulation of ras gtpase activityGO:0032320280.024
regulation of cellular component biogenesisGO:0044087860.024
Mouse
calcium mediated signaling using intracellular calcium sourceGO:003558410.024
positive regulation of catalytic activityGO:00430851840.024
positive regulation of rna metabolic processGO:00512542030.023
cellular amine metabolic processGO:0044106380.023
ribonucleoside metabolic processGO:00091191740.023
positive regulation of cellular biosynthetic processGO:00313282950.023
carbohydrate derivative catabolic processGO:19011361470.023
oxoacid metabolic processGO:00434362900.023
ribonucleoside triphosphate metabolic processGO:00091991410.022
nucleotide catabolic processGO:00091661390.022
epithelium developmentGO:0060429960.022
Mouse
positive regulation of cellular catabolic processGO:0031331710.022
anatomical structure morphogenesisGO:00096532980.022
Mouse
purine ribonucleoside metabolic processGO:00461281680.022
amine metabolic processGO:0009308380.021
guanosine containing compound catabolic processGO:1901069710.021
single organism reproductive processGO:00447022970.021
regulation of proteolysisGO:0030162660.021
protein oligomerizationGO:00512591910.021
central nervous system developmentGO:00074173110.021
Mouse Rat
anterior posterior pattern specificationGO:000995210.021
regulation of nucleoside metabolic processGO:0009118660.021
positive regulation of cellular component organizationGO:00511302000.020
Mouse Rat
regulation of cellular ketone metabolic processGO:0010565270.020
positive regulation of cell projection organizationGO:00313461110.020
Mouse Rat
positive regulation of gtpase activityGO:0043547470.020
regulation of nucleotide catabolic processGO:0030811650.020
negative regulation of nucleic acid templated transcriptionGO:19035071170.020
positive regulation of developmental processGO:00510942830.019
Mouse Rat
positive regulation of macromolecule biosynthetic processGO:00105572470.019
positive regulation of biosynthetic processGO:00098913190.019
positive regulation of cellular component movementGO:00512721020.019
cytoskeleton organizationGO:00070101110.019
Mouse
guanosine containing compound metabolic processGO:1901068740.019
purine nucleoside catabolic processGO:00061521240.019
macromolecule catabolic processGO:0009057580.019
carboxylic acid metabolic processGO:00197522890.019
positive regulation of phosphate metabolic processGO:00459372620.018
cyclic nucleotide metabolic processGO:0009187800.018
negative regulation of metabolic processGO:00098923310.018
positive regulation of nucleobase containing compound metabolic processGO:00459353190.018
positive regulation of phosphorus metabolic processGO:00105622620.018
tissue developmentGO:00098882520.018
Mouse
regulation of nucleotide metabolic processGO:00061401170.018
negative regulation of protein import into nucleus translocationGO:003315910.018
regulation of protein catabolic processGO:0042176160.018
regulation of cellular amine metabolic processGO:003323880.018
head developmentGO:00603222470.018
Mouse Rat
positive regulation of nucleotide catabolic processGO:0030813530.018
response to biotic stimulusGO:00096072260.018
circadian regulation of gene expressionGO:003292230.018
localization of cellGO:00516742020.017
nucleoside triphosphate metabolic processGO:00091411440.017
positive regulation of molecular functionGO:00440932300.017
Mouse
regulation of cell migrationGO:00303341280.017
regulation of purine nucleotide catabolic processGO:0033121650.017
cellular ketone metabolic processGO:0042180510.017
positive regulation of nucleic acid templated transcriptionGO:19035081970.017
cell cell signalingGO:00072673350.017
Mouse
negative regulation of transportGO:00510511360.017
cellular component movementGO:00069282480.016
regulation of anatomical structure morphogenesisGO:00226031410.016
Mouse
regulation of transferase activityGO:00513381230.016
regulation of anatomical structure sizeGO:00900661350.016
purine nucleoside triphosphate metabolic processGO:00091441410.016
ribonucleoside catabolic processGO:00424541260.016
nucleotide biosynthetic processGO:0009165980.016
regulation of cell motilityGO:20001451310.016
regulation of synapse maturationGO:009012820.016
immune system developmentGO:0002520410.016
single organism catabolic processGO:00447122830.016
glycosyl compound catabolic processGO:19016581260.016
negative regulation of vascular permeabilityGO:004311630.015
immune system processGO:00023762040.015
regulation of gtp catabolic processGO:0033124580.015
positive regulation of cell developmentGO:00107201760.015
Mouse Rat
cell morphogenesis involved in differentiationGO:00009041190.015
Mouse
glycosyl compound metabolic processGO:19016571820.015
circulatory system processGO:00030131830.015
regulation of receptor activityGO:0010469290.015
Mouse
positive regulation of catabolic processGO:0009896780.015
neuron developmentGO:00486662860.015
Mouse Rat
regulation of protein kinase activityGO:00458591050.015
response to bacteriumGO:00096172000.015
purine nucleoside metabolic processGO:00422781690.015
cellular homeostasisGO:00197252520.015
Mouse
defense responseGO:00069521940.015
Mouse
cell morphogenesis involved in neuron differentiationGO:00486671060.015
Mouse
regulation of phosphate metabolic processGO:00192203490.015
leukocyte differentiationGO:0002521300.014
autophagic cell deathGO:004810240.014
regulation of cellular protein catabolic processGO:190336270.014
macromolecular complex assemblyGO:00650032730.014
regulation of neurogenesisGO:00507672470.014
Mouse Rat
response to metal ionGO:00100382530.014
macromolecular complex subunit organizationGO:00439333390.014
hematopoietic or lymphoid organ developmentGO:0048534360.014
reproductive processGO:00224143720.014
regulation of cellular component movementGO:00512701500.014
positive regulation of cellular amine metabolic processGO:003324030.014
positive regulation of nervous system developmentGO:00519621780.014
Mouse Rat
regulation of cell differentiationGO:00455953200.014
Mouse Rat
positive regulation of rna biosynthetic processGO:19026801970.014
positive regulation of neurogenesisGO:00507691650.014
Mouse Rat
neurotransmitter gated ion channel clusteringGO:007257830.014
Mouse
purine nucleoside triphosphate catabolic processGO:00091461220.013
protein localization to synapseGO:003541850.013
gamete generationGO:00072761240.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
negative regulation of cellular metabolic processGO:00313242810.013
secretion by cellGO:00329402480.013
apoptotic processGO:00069153810.013
nucleoside triphosphate catabolic processGO:00091431230.013
positive regulation of gtp catabolic processGO:0033126480.013
g protein coupled receptor signaling pathwayGO:00071862420.013
carbohydrate derivative biosynthetic processGO:19011371240.013
regulation of heart contractionGO:0008016480.013
cortical actin cytoskeleton organizationGO:003086620.012
nucleoside catabolic processGO:00091641260.012
t cell selectionGO:004505810.012
cellular component morphogenesisGO:00329891550.012
Mouse
rho protein signal transductionGO:0007266110.012
regulation of ras gtpase activityGO:0032318320.012
regulation of canonical wnt signaling pathwayGO:006082840.012
actin filament based processGO:0030029860.012
Mouse
organophosphate biosynthetic processGO:00904071430.012
positive regulation of response to stimulusGO:00485842850.012
positive regulation of phosphorylationGO:00423271770.012
positive regulation of protein phosphorylationGO:00019341350.012
regulation of transcription dna templatedGO:00063553740.012
positive regulation of transcription dna templatedGO:00458931970.012
positive regulation of cellular protein metabolic processGO:00322701670.012
glycerolipid metabolic processGO:0046486670.012
cell migrationGO:00164771970.011
positive regulation of protein metabolic processGO:00512471780.011
positive regulation of programmed cell deathGO:00430681570.011
forebrain developmentGO:0030900980.011
Mouse
positive regulation of hydrolase activityGO:0051345860.011
regulation of cyclic nucleotide biosynthetic processGO:0030802450.011
single organism behaviorGO:00447081300.011
Mouse
developmental growthGO:00485891000.011
cytoplasmic transportGO:00164821150.011
chemical homeostasisGO:00488782920.011
regulation of blood vessel sizeGO:0050880890.011
positive regulation of cell differentiationGO:00455972170.011
Mouse Rat
locomotionGO:00400112370.011
positive regulation of neuron migrationGO:200122420.011
nucleoside phosphate biosynthetic processGO:19012931020.011
aggresome assemblyGO:007084210.011
response to external biotic stimulusGO:00432072210.011
cellular protein catabolic processGO:0044257190.011
regulation of defense responseGO:0031347680.011
Mouse
defense response to gram negative bacteriumGO:005082930.010
heart morphogenesisGO:000300730.010
circadian rhythmGO:0007623880.010
regulation of synapse structure and activityGO:0050803210.010
Mouse
ribonucleotide biosynthetic processGO:0009260850.010
negative regulation of signalingGO:00230571570.010
Mouse
cellular response to organic cyclic compoundGO:00714072020.010
male gamete generationGO:0048232990.010
negative regulation of biosynthetic processGO:00098901680.010
multicellular organism growthGO:003526410.010
regulation of ras protein signal transductionGO:0046578450.010
sexual reproductionGO:00199531480.010
cellular chemical homeostasisGO:00550822470.010
cellular lipid metabolic processGO:00442552080.010
response to decreased oxygen levelsGO:00362932370.010

Shank3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
nervous system diseaseDOID:86300.029
central nervous system diseaseDOID:33100.015
sensory system diseaseDOID:005015500.015