IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Calr4

calreticulin 4

Ensembl: ENSRNOG00000037710
RGD: 1591090
Entrez: 689537

Process Predictions
Disease Predictions

Calr4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
neurological system process	GO:0050877	219	0.118
transmembrane transport	GO:0055085	412	0.111
cell motility	GO:0048870	202	0.083
response to temperature stimulus	GO:0009266	94	0.080
cell cell signaling	GO:0007267	335	0.070
cellular component movement	GO:0006928	248	0.066
regulation of cellular localization	GO:0060341	263	0.065
single organism reproductive process	GO:0044702	297	0.063	Rat
ion transmembrane transport	GO:0034220	365	0.063
secretion by cell	GO:0032940	248	0.052
inorganic cation transmembrane transport	GO:0098662	202	0.049
carboxylic acid metabolic process	GO:0019752	289	0.047
homeostatic process	GO:0042592	331	0.046
cellular homeostasis	GO:0019725	252	0.046
organic acid metabolic process	GO:0006082	292	0.046
multi organism reproductive process	GO:0044703	262	0.045	Rat
positive regulation of cell communication	GO:0010647	271	0.043
nitrogen compound transport	GO:0071705	229	0.043
positive regulation of neurogenesis	GO:0050769	165	0.043
regulation of rna biosynthetic process	GO:2001141	381	0.041
localization of cell	GO:0051674	202	0.039
regulation of hormone secretion	GO:0046883	106	0.036
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.035
macromolecule localization	GO:0033036	252	0.035
head development	GO:0060322	247	0.034
cellular component biogenesis	GO:0044085	368	0.033
regulation of transmembrane transport	GO:0034762	122	0.032
inorganic ion transmembrane transport	GO:0098660	229	0.032
amine metabolic process	GO:0009308	38	0.032
sex differentiation	GO:0007548	113	0.031
locomotion	GO:0040011	237	0.031
response to corticosteroid	GO:0031960	235	0.031
regulation of secretion by cell	GO:1903530	208	0.031
regulation of nervous system development	GO:0051960	264	0.030
developmental process involved in reproduction	GO:0003006	159	0.030
reproduction	GO:0000003	245	0.030	Rat
central nervous system development	GO:0007417	311	0.029
regulation of multicellular organismal development	GO:2000026	376	0.029
signal release	GO:0023061	145	0.028
regulation of cellular amino acid metabolic process	GO:0006521	2	0.028
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.028
response to growth factor	GO:0070848	189	0.027
positive regulation of cell death	GO:0010942	184	0.027
reproductive structure development	GO:0048608	128	0.027
multicellular organismal reproductive process	GO:0048609	233	0.027	Rat
positive regulation of nervous system development	GO:0051962	178	0.027
positive regulation of signaling	GO:0023056	270	0.027
nucleic acid templated transcription	GO:0097659	379	0.026
rna metabolic process	GO:0016070	406	0.025
regulation of secretion	GO:0051046	224	0.025
signal transduction by phosphorylation	GO:0023014	144	0.024
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.024
oxoacid metabolic process	GO:0043436	290	0.024
protein localization	GO:0008104	191	0.024
regulation of transcription dna templated	GO:0006355	374	0.024
transcription from rna polymerase ii promoter	GO:0006366	252	0.023
regulation of system process	GO:0044057	208	0.023
regulation of membrane potential	GO:0042391	110	0.022
positive regulation of gene expression	GO:0010628	244	0.022
response to decreased oxygen levels	GO:0036293	237	0.022
regulation of signal transduction	GO:0009966	318	0.022
intracellular signal transduction	GO:0035556	314	0.022
action potential	GO:0001508	54	0.022
calcium mediated signaling	GO:0019722	23	0.021
regulation of cell differentiation	GO:0045595	320	0.021
positive regulation of cell differentiation	GO:0045597	217	0.021
regulation of cellular amine metabolic process	GO:0033238	8	0.021
regulation of ion transmembrane transport	GO:0034765	121	0.020
regulation of cellular ketone metabolic process	GO:0010565	27	0.020
cellular response to growth factor stimulus	GO:0071363	162	0.020
cation transmembrane transport	GO:0098655	263	0.020
regulation of nucleic acid templated transcription	GO:1903506	380	0.020
response to metal ion	GO:0010038	253	0.020	Rat
rna biosynthetic process	GO:0032774	380	0.020
response to bacterium	GO:0009617	200	0.019
reproductive system development	GO:0061458	128	0.019
carbohydrate metabolic process	GO:0005975	130	0.019
regulation of molecular function	GO:0065009	398	0.019
positive regulation of developmental process	GO:0051094	283	0.018
reproductive process	GO:0022414	372	0.018	Rat
response to cytokine	GO:0034097	215	0.018
single organism cellular localization	GO:1902580	102	0.018
positive regulation of rna biosynthetic process	GO:1902680	197	0.018
cellular amine metabolic process	GO:0044106	38	0.018
metal ion transport	GO:0030001	289	0.017
chemical homeostasis	GO:0048878	292	0.017
cellular lipid metabolic process	GO:0044255	208	0.017
positive regulation of neuron differentiation	GO:0045666	126	0.017
secretion	GO:0046903	307	0.017
ras protein signal transduction	GO:0007265	29	0.017
hormone transport	GO:0009914	121	0.017
positive regulation of biosynthetic process	GO:0009891	319	0.017
positive regulation of cell development	GO:0010720	176	0.017
protein complex biogenesis	GO:0070271	263	0.017
positive regulation of cellular biosynthetic process	GO:0031328	295	0.017
cellular ketone metabolic process	GO:0042180	51	0.016
transcription dna templated	GO:0006351	377	0.016
response to cold	GO:0009409	29	0.016
positive regulation of rna metabolic process	GO:0051254	203	0.016
cellular amino acid metabolic process	GO:0006520	107	0.016
cellular response to hypoxia	GO:0071456	51	0.016
brain development	GO:0007420	247	0.016
positive regulation of synaptic transmission	GO:0050806	62	0.016
regulation of cellular component organization	GO:0051128	368	0.015
divalent inorganic cation homeostasis	GO:0072507	165	0.015
growth	GO:0040007	165	0.015
ion homeostasis	GO:0050801	212	0.015
regulation of cellular component movement	GO:0051270	150	0.015
negative regulation of programmed cell death	GO:0043069	183	0.015
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.015
positive regulation of transport	GO:0051050	245	0.015
development of primary sexual characteristics	GO:0045137	107	0.015
cellular cation homeostasis	GO:0030003	180	0.015
cellular catabolic process	GO:0044248	295	0.015
cellular chemical homeostasis	GO:0055082	247	0.014
organic hydroxy compound metabolic process	GO:1901615	115	0.014
positive regulation of molecular function	GO:0044093	230	0.014
cellular response to oxygen levels	GO:0071453	60	0.014
cellular response to cytokine stimulus	GO:0071345	127	0.014
small gtpase mediated signal transduction	GO:0007264	36	0.014
response to peptide hormone	GO:0043434	278	0.014
programmed cell death	GO:0012501	392	0.014
membrane organization	GO:0061024	94	0.014
positive regulation of transcription dna templated	GO:0045893	197	0.013
positive regulation of phosphorylation	GO:0042327	177	0.013
regulation of neurogenesis	GO:0050767	247	0.013
positive regulation of cellular amine metabolic process	GO:0033240	3	0.013
cellular ion homeostasis	GO:0006873	184	0.013
negative regulation of metabolic process	GO:0009892	331	0.013	Rat
amide transport	GO:0042886	105	0.013
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.013
monosaccharide metabolic process	GO:0005996	61	0.013
regulation of catalytic activity	GO:0050790	304	0.013
protein complex assembly	GO:0006461	263	0.013
organelle organization	GO:0006996	266	0.012
single organism carbohydrate metabolic process	GO:0044723	118	0.012
regulation of heart rate	GO:0002027	16	0.012
neuron death	GO:0070997	127	0.012
single organism membrane organization	GO:0044802	74	0.012
proteolysis	GO:0006508	175	0.012
single organism carbohydrate catabolic process	GO:0044724	40	0.012
response to hypoxia	GO:0001666	231	0.012
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.012
sodium ion transmembrane transport	GO:0035725	67	0.012
response to carbohydrate	GO:0009743	183	0.012
negative regulation of multicellular organismal process	GO:0051241	203	0.012
positive regulation of apoptotic process	GO:0043065	154	0.012
regulation of cell development	GO:0060284	263	0.012
positive regulation of cell proliferation	GO:0008284	249	0.012
regulation of neuron projection development	GO:0010975	161	0.011
positive regulation of response to stimulus	GO:0048584	285	0.011
response to glucocorticoid	GO:0051384	223	0.011
reactive nitrogen species metabolic process	GO:2001057	1	0.011
multi multicellular organism process	GO:0044706	138	0.011
rhythmic process	GO:0048511	156	0.011
monocarboxylic acid metabolic process	GO:0032787	152	0.011
regulation of growth	GO:0040008	105	0.011
maintenance of location	GO:0051235	17	0.011
protein homooligomerization	GO:0051260	91	0.011
embryonic pattern specification	GO:0009880	1	0.011
positive regulation of locomotion	GO:0040017	102	0.011
generation of precursor metabolites and energy	GO:0006091	62	0.011
response to inorganic substance	GO:0010035	377	0.011	Rat
response to oxygen levels	GO:0070482	265	0.010
response to external biotic stimulus	GO:0043207	221	0.010
macromolecular complex assembly	GO:0065003	273	0.010
reactive oxygen species biosynthetic process	GO:1903409	8	0.010
embryonic skeletal system development	GO:0048706	3	0.010
regulation of hormone levels	GO:0010817	187	0.010

Calr4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.017
nervous system disease	DOID:863	0.017
substance dependence	DOID:9973	0.014
substance related disorder	DOID:303	0.014
disease of mental health	DOID:150	0.014

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