Rattus norvegicus

0 known processes

Cul1

cullin 1

Cul1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of metabolic processGO:00098923310.168
negative regulation of nucleobase containing compound metabolic processGO:00459341530.105
rna biosynthetic processGO:00327743800.101
single organism reproductive processGO:00447022970.093
rna metabolic processGO:00160704060.084
negative regulation of nitrogen compound metabolic processGO:00511721610.074
regulation of rna metabolic processGO:00512523910.056
cellular component biogenesisGO:00440853680.055
reproductive processGO:00224143720.054
negative regulation of macromolecule metabolic processGO:00106052600.053
response to decreased oxygen levelsGO:00362932370.050
negative regulation of macromolecule biosynthetic processGO:00105581480.049
reproductionGO:00000032450.048
negative regulation of cellular biosynthetic processGO:00313271610.048
macromolecular complex subunit organizationGO:00439333390.047
multicellular organismal reproductive processGO:00486092330.046
organic substance catabolic processGO:19015753160.044
Human Mouse Fly
negative regulation of gene expressionGO:00106291990.043
regulation of transcription dna templatedGO:00063553740.043
metaphase plate congressionGO:005131010.042
multi organism reproductive processGO:00447032620.041
organelle organizationGO:00069962660.040
cellular amino acid metabolic processGO:00065201070.040
response to oxygen levelsGO:00704822650.039
nucleic acid templated transcriptionGO:00976593790.039
multicellular organism reproductionGO:00325042330.037
anterior posterior pattern specificationGO:000995210.037
cytoskeleton organizationGO:00070101110.036
organic acid metabolic processGO:00060822920.035
cellular catabolic processGO:00442482950.033
Human Mouse
sexual reproductionGO:00199531480.033
proteolysisGO:00065081750.032
Human Mouse
negative regulation of nucleic acid templated transcriptionGO:19035071170.032
negative regulation of rna metabolic processGO:00512531230.032
regulation of molecular functionGO:00650093980.031
cellular macromolecule localizationGO:00707271220.031
ion transmembrane transportGO:00342203650.031
negative regulation of cellular metabolic processGO:00313242810.030
regulation of cellular localizationGO:00603412630.030
cellular component assemblyGO:00226073600.029
transcription dna templatedGO:00063513770.028
regulation of rna biosynthetic processGO:20011413810.027
regulation of programmed cell deathGO:00430673410.027
Fly
regulation of neurogenesisGO:00507672470.026
single organism catabolic processGO:00447122830.026
negative regulation of response to stimulusGO:00485851550.026
Fly
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.026
gamete generationGO:00072761240.026
cell projection organizationGO:00300303020.025
positive regulation of cellular component organizationGO:00511302000.025
purine containing compound metabolic processGO:00725212530.025
positive regulation of nucleobase containing compound metabolic processGO:00459353190.025
single organism intracellular transportGO:19025821660.025
cation transportGO:00068123820.025
actin cytoskeleton organizationGO:0030036730.025
negative regulation of rna biosynthetic processGO:19026791180.024
organonitrogen compound catabolic processGO:19015651790.024
response to woundingGO:00096112540.024
regulation of nucleic acid templated transcriptionGO:19035063800.024
carboxylic acid metabolic processGO:00197522890.024
oxoacid metabolic processGO:00434362900.024
regulation of signal transductionGO:00099663180.023
Fly
macromolecule localizationGO:00330362520.023
synaptic transmissionGO:00072682350.023
regulation of cellular component organizationGO:00511283680.023
alpha amino acid metabolic processGO:1901605710.023
purine ribonucleotide metabolic processGO:00091502270.023
regulation of sister chromatid segregationGO:003304510.023
macromolecular complex assemblyGO:00650032730.023
response to hypoxiaGO:00016662310.022
neuron differentiationGO:00301823680.022
Fly
positive regulation of nitrogen compound metabolic processGO:00511733340.022
neuron developmentGO:00486662860.022
Fly
multi multicellular organism processGO:00447061380.022
response to nutrientGO:00075842480.021
inorganic ion transmembrane transportGO:00986602290.021
nucleobase containing small molecule metabolic processGO:00550863160.021
developmental process involved in reproductionGO:00030061590.021
dna packagingGO:000632340.020
protein complex assemblyGO:00064612630.020
regulation of phosphorus metabolic processGO:00511743490.020
regulation of apoptotic processGO:00429813350.020
Fly
embryonic axis specificationGO:000057810.020
locomotionGO:00400112370.020
protein complex biogenesisGO:00702712630.020
cellular response to oxygen containing compoundGO:19017013860.020
Fly
negative regulation of transcription dna templatedGO:00458921160.020
metal ion transportGO:00300012890.019
chromosome segregationGO:000705920.019
central nervous system developmentGO:00074173110.019
transmembrane transportGO:00550854120.019
cell projection morphogenesisGO:00488581230.019
positive regulation of rna metabolic processGO:00512542030.019
positive regulation of phosphate metabolic processGO:00459372620.019
regulation of mrna splicing via spliceosomeGO:004802430.019
cellular response to stressGO:00335542690.019
Fly
mitotic sister chromatid separationGO:005130610.019
cellular protein catabolic processGO:0044257190.019
Human Mouse
regulation of cellular protein metabolic processGO:00322682670.018
transcription from rna polymerase ii promoterGO:00063662520.018
positive regulation of phosphorus metabolic processGO:00105622620.018
aromatic compound catabolic processGO:00194391680.018
regulation of protein modification processGO:00313991940.018
cognitionGO:0050890920.018
intracellular signal transductionGO:00355563140.018
Fly
positive regulation of gene expressionGO:00106282440.017
regulation of cellular amino acid metabolic processGO:000652120.017
cellular response to endogenous stimulusGO:00714953770.017
Fly
protein complex subunit organizationGO:00718223020.017
small gtpase mediated signal transductionGO:0007264360.017
metaphase anaphase transition of cell cycleGO:004478410.017
purine ribonucleoside metabolic processGO:00461281680.017
apoptotic processGO:00069153810.017
Mouse Fly
immune responseGO:00069551040.017
metaphase anaphase transition of mitotic cell cycleGO:000709110.017
positive regulation of cell projection organizationGO:00313461110.017
gastrulationGO:000736920.017
purine ribonucleoside monophosphate catabolic processGO:0009169550.016
regulation of cellular amine metabolic processGO:003323880.016
negative regulation of biosynthetic processGO:00098901680.016
behaviorGO:00076102050.016
purine ribonucleoside triphosphate metabolic processGO:00092051400.016
heterocycle catabolic processGO:00467001670.016
embryonic pattern specificationGO:000988010.016
regulation of cellular ketone metabolic processGO:0010565270.016
defense responseGO:00069521940.016
positive regulation of molecular functionGO:00440932300.015
regulation of gene expression epigeneticGO:0040029100.015
actin filament based processGO:0030029860.015
purine ribonucleoside catabolic processGO:00461301240.015
purine nucleotide catabolic processGO:00061951360.015
ras protein signal transductionGO:0007265290.015
sex differentiationGO:00075481130.015
cellular response to organic cyclic compoundGO:00714072020.015
gonad developmentGO:00084061040.015
establishment of protein localizationGO:00451841410.015
response to nutrient levelsGO:00316673700.015
intracellular transportGO:00469071850.015
regulation of chromosome segregationGO:005198310.015
protein modification by small protein conjugation or removalGO:0070647350.014
Human Mouse
regulation of proteasomal protein catabolic processGO:006113640.014
axis specificationGO:000979840.014
positive regulation of nucleotide metabolic processGO:0045981910.014
regulation of catalytic activityGO:00507903040.014
sister chromatid segregationGO:000081910.014
positive regulation of catalytic activityGO:00430851840.014
neurological system processGO:00508772190.014
head developmentGO:00603222470.014
proteolysis involved in cellular protein catabolic processGO:0051603190.014
Human Mouse
carbohydrate derivative metabolic processGO:19011353460.014
positive regulation of transportGO:00510502450.014
cellular protein localizationGO:00346131220.014
negative regulation of cellular protein metabolic processGO:00322691060.014
vesicle mediated transportGO:00161921810.014
rna localizationGO:000640340.014
single organism organelle organizationGO:19025891800.013
chromosome separationGO:005130410.013
regulation of mitotic sister chromatid segregationGO:003304710.013
ribose phosphate metabolic processGO:00196932350.013
purine containing compound catabolic processGO:00725231380.013
embryo developmentGO:0009790490.013
positive regulation of cellular amine metabolic processGO:003324030.013
regulation of cell differentiationGO:00455953200.013
enzyme linked receptor protein signaling pathwayGO:00071671160.013
Fly
response to estrogenGO:00436272320.012
ribonucleoside metabolic processGO:00091191740.012
maintenance of locationGO:0051235170.012
neuron projection morphogenesisGO:00488121220.012
ribonucleotide catabolic processGO:00092611360.012
reproductive structure developmentGO:00486081280.012
single organism cellular localizationGO:19025801020.012
monovalent inorganic cation transportGO:00156721720.012
anion transportGO:00068201780.012
endocytosisGO:0006897840.012
cellular amine metabolic processGO:0044106380.012
organic cyclic compound catabolic processGO:19013611750.012
neuromuscular synaptic transmissionGO:000727420.012
positive regulation of protein modification processGO:00314011420.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
response to growth factorGO:00708481890.012
brain developmentGO:00074202470.012
dephosphorylationGO:0016311980.012
regulation of multicellular organismal developmentGO:20000263760.011
immune system processGO:00023762040.011
carbohydrate derivative catabolic processGO:19011361470.011
regulation of response to stressGO:00801341260.011
cation transmembrane transportGO:00986552630.011
nucleoside phosphate metabolic processGO:00067532830.011
regulation of cell growthGO:0001558850.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
axonogenesisGO:0007409710.011
regulation of neuron differentiationGO:00456642080.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:003114510.011
wound healingGO:00420601220.011
amine metabolic processGO:0009308380.011
spermatogenesisGO:0007283990.011
catabolic processGO:00090563510.011
Human Mouse Fly
positive regulation of signal transductionGO:00099671750.011
ribonucleoside catabolic processGO:00424541260.011
response to corticosteroidGO:00319602350.011
organophosphate catabolic processGO:00464341480.011
positive regulation of rna biosynthetic processGO:19026801970.011
regulation of intracellular transportGO:0032386650.011
regulation of cell projection organizationGO:00313441750.011
nucleotide catabolic processGO:00091661390.011
single organism nuclear importGO:1902593350.011
male gamete generationGO:0048232990.011
sulfur compound metabolic processGO:0006790700.010
multicellular organism growthGO:003526410.010
response to carbohydrateGO:00097431830.010
nucleobase containing compound catabolic processGO:00346551520.010
establishment of chromosome localizationGO:005130310.010
purine nucleoside metabolic processGO:00422781690.010
cell part morphogenesisGO:00329901230.010
response to external biotic stimulusGO:00432072210.010
protein localizationGO:00081041910.010
cell cell signalingGO:00072673350.010

Cul1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.036
disease of anatomical entityDOID:700.036
muscular diseaseDOID:008000000.036
muscle tissue diseaseDOID:6600.036
myopathyDOID:42300.033
muscular dystrophyDOID:988400.026