Rattus norvegicus

25 known processes

P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

(Aliases: P2x6,Rnap2x6,P2rxl1)

P2rx6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transmembrane transportGO:00986552630.899
transmembrane transportGO:00550854120.810
regulation of ion transportGO:00432692450.550
Rat
ion transmembrane transportGO:00342203650.517
inorganic cation transmembrane transportGO:00986622020.446
cell cell signalingGO:00072673350.368
Rat
rna metabolic processGO:00160704060.301
inorganic ion transmembrane transportGO:00986602290.292
homeostatic processGO:00425923310.210
regulation of ion transmembrane transportGO:00347651210.210
sodium ion transportGO:0006814820.202
Rat
regulation of transmembrane transportGO:00347621220.191
regulation of signal transductionGO:00099663180.191
monovalent inorganic cation transportGO:00156721720.180
Rat
regulation of multicellular organismal developmentGO:20000263760.179
Rat
organic acid transportGO:00158491160.178
transmission of nerve impulseGO:0019226420.171
Rat
chemical homeostasisGO:00488782920.150
regulation of phosphorus metabolic processGO:00511743490.148
action potentialGO:0001508540.145
Rat
regulation of organ formationGO:000315620.143
anion transportGO:00068201780.137
cellular chemical homeostasisGO:00550822470.135
multicellular organismal signalingGO:0035637440.134
Rat
protein complex biogenesisGO:00702712630.132
regulation of anion transportGO:0044070430.131
regulation of neuron differentiationGO:00456642080.128
metal ion transportGO:00300012890.127
Rat
cellular homeostasisGO:00197252520.124
carboxylic acid transportGO:00469421150.123
protein oligomerizationGO:00512591910.121
anatomical structure morphogenesisGO:00096532980.120
cell projection organizationGO:00300303020.115
cellular component biogenesisGO:00440853680.114
neuron neuron synaptic transmissionGO:0007270600.111
Rat
nucleic acid templated transcriptionGO:00976593790.108
potassium ion transmembrane transportGO:0071805710.107
protein complex subunit organizationGO:00718223020.104
cellular component assemblyGO:00226073600.104
sodium ion transmembrane transportGO:0035725670.103
neurological system processGO:00508772190.101
Rat
positive regulation of multicellular organismal processGO:00512403870.098
regulation of intracellular signal transductionGO:19025312180.093
brain developmentGO:00074202470.090
ion homeostasisGO:00508012120.089
regulation of phosphate metabolic processGO:00192203490.085
regulation of metal ion transportGO:00109591180.083
Rat
rhythmic processGO:00485111560.083
cellular divalent inorganic cation homeostasisGO:00725031620.082
ensheathment of neuronsGO:0007272400.078
transcription dna templatedGO:00063513770.077
cellular response to oxygen containing compoundGO:19017013860.076
central nervous system developmentGO:00074173110.074
organic anion transportGO:00157111320.073
cation transportGO:00068123820.072
regulation of homeostatic processGO:00328441010.071
developmental inductionGO:003112820.070
myelinationGO:0042552390.067
regulation of membrane potentialGO:00423911100.065
Rat
macromolecular complex assemblyGO:00650032730.065
positive regulation of phosphorus metabolic processGO:00105622620.062
positive regulation of gene expressionGO:00106282440.061
cellular potassium ion transportGO:0071804720.061
positive regulation of nucleobase containing compound metabolic processGO:00459353190.059
organonitrogen compound biosynthetic processGO:19015661670.059
regulation of sodium ion transmembrane transporter activityGO:200064940.054
positive regulation of ion transportGO:0043270940.053
acid secretionGO:0046717480.053
neuronal action potentialGO:0019228350.052
Rat
synaptic transmissionGO:00072682350.052
Rat
behaviorGO:00076102050.052
single organism intracellular transportGO:19025821660.051
regulation of rna biosynthetic processGO:20011413810.051
positive regulation of phosphorylationGO:00423271770.051
positive regulation of transcription dna templatedGO:00458931970.050
monocarboxylic acid transportGO:0015718520.050
response to molecule of bacterial originGO:00022371940.049
positive regulation of response to stimulusGO:00485842850.049
tissue developmentGO:00098882520.048
Rat
organelle organizationGO:00069962660.048
regulation of apoptotic processGO:00429813350.047
positive regulation of nitrogen compound metabolic processGO:00511733340.047
muscle contractionGO:0006936880.046
anion transmembrane transportGO:0098656770.046
carboxylic acid metabolic processGO:00197522890.046
regulation of nucleic acid templated transcriptionGO:19035063800.045
regulation of cellular component organizationGO:00511283680.044
regulation of transporter activityGO:0032409500.044
organophosphate metabolic processGO:00196373700.043
rna biosynthetic processGO:00327743800.043
cellular response to abiotic stimulusGO:0071214850.042
adult locomotory behaviorGO:000834440.042
neuron developmentGO:00486662860.042
regulation of neuron projection developmentGO:00109751610.041
organ formationGO:004864530.040
single organism behaviorGO:00447081300.040
regulation of ion transmembrane transporter activityGO:0032412480.040
defense responseGO:00069521940.040
amino acid transportGO:0006865700.040
response to purine containing compoundGO:00140741260.039
positive regulation of cellular protein metabolic processGO:00322701670.039
single organism organelle organizationGO:19025891800.038
positive regulation of phosphate metabolic processGO:00459372620.038
cell morphogenesisGO:00009021420.038
actin filament based processGO:0030029860.038
response to inorganic substanceGO:00100353770.038
cellular response to nitrogen compoundGO:19016992100.037
protein homooligomerizationGO:0051260910.037
Human Rat
cellular calcium ion homeostasisGO:00068741600.037
positive regulation of signal transductionGO:00099671750.037
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633930.037
muscle system processGO:00030121150.036
regulation of rna metabolic processGO:00512523910.036
organic acid metabolic processGO:00060822920.036
macromolecular complex subunit organizationGO:00439333390.036
positive regulation of signalingGO:00230562700.036
cytoskeleton organizationGO:00070101110.036
head developmentGO:00603222470.035
response to organophosphorusGO:00466831020.035
regulation of molecular functionGO:00650093980.035
negative regulation of developmental processGO:00510931250.034
negative regulation of nervous system developmentGO:0051961790.034
positive regulation of macromolecule biosynthetic processGO:00105572470.034
divalent inorganic cation homeostasisGO:00725071650.034
g protein coupled receptor signaling pathwayGO:00071862420.034
neuron projection developmentGO:00311752730.033
response to bacteriumGO:00096172000.033
regulation of cell differentiationGO:00455953200.033
macromolecule localizationGO:00330362520.033
regulation of transcription dna templatedGO:00063553740.033
programmed cell deathGO:00125013920.033
negative regulation of cell developmentGO:0010721820.032
calcium ion homeostasisGO:00550741620.032
secretionGO:00469033070.032
defecationGO:003042110.032
regulation of mapk cascadeGO:00434081160.032
intracellular signal transductionGO:00355563140.031
nucleobase containing small molecule metabolic processGO:00550863160.031
regulation of synaptic transmissionGO:00508041410.031
regulation of cellular amine metabolic processGO:003323880.031
response to external biotic stimulusGO:00432072210.031
positive regulation of mapk cascadeGO:0043410920.031
positive regulation of molecular functionGO:00440932300.030
negative regulation of transcription dna templatedGO:00458921160.030
positive regulation of nucleic acid templated transcriptionGO:19035081970.030
regulation of cell proliferationGO:00421273590.030
cellular response to endogenous stimulusGO:00714953770.030
nucleoside phosphate metabolic processGO:00067532830.030
negative regulation of cell differentiationGO:0045596990.030
camera type eye developmentGO:0043010480.030
regulation of cell fate commitmentGO:001045310.029
calcium ion transportGO:00068161310.029
regulation of protein phosphorylationGO:00019321830.029
calcium ion transport into cytosolGO:0060402380.029
glycerolipid metabolic processGO:0046486670.028
regulation of transcription from rna polymerase ii promoterGO:00063572340.028
synapse assemblyGO:0007416290.028
cellular response to cytokine stimulusGO:00713451270.028
sensory perceptionGO:00076001010.028
Rat
camp biosynthetic processGO:0006171470.027
negative regulation of multicellular organismal processGO:00512412030.027
organophosphate biosynthetic processGO:00904071430.026
positive regulation of biosynthetic processGO:00098913190.026
positive regulation of brown fat cell proliferationGO:007034910.026
cellular response to growth factor stimulusGO:00713631620.026
transcription from rna polymerase ii promoterGO:00063662520.025
positive regulation of camp biosynthetic processGO:0030819280.025
neuron differentiationGO:00301823680.025
lipid metabolic processGO:00066292830.025
positive regulation of rna metabolic processGO:00512542030.025
positive regulation of calcium ion transportGO:0051928360.025
cellular amine metabolic processGO:0044106380.025
protein complex assemblyGO:00064612630.025
regulation of cellular amino acid metabolic processGO:000652120.025
single organism membrane organizationGO:0044802740.024
regulation of phosphorylationGO:00423252480.024
cellular component morphogenesisGO:00329891550.024
cellular response to organonitrogen compoundGO:00714171970.024
response to radiationGO:00093141370.024
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.024
regulation of transmembrane transporter activityGO:0022898490.024
cellular amino acid metabolic processGO:00065201070.023
protein tetramerizationGO:0051262380.023
negative regulation of neurogenesisGO:0050768780.023
negative regulation of nucleobase containing compound metabolic processGO:00459341530.023
purine ribonucleotide metabolic processGO:00091502270.023
ribose phosphate biosynthetic processGO:0046390870.023
negative regulation of response to stimulusGO:00485851550.023
positive regulation of cellular biosynthetic processGO:00313282950.023
response to metal ionGO:00100382530.023
purine containing compound biosynthetic processGO:0072522850.022
positive regulation of fat cell proliferationGO:007034610.022
response to growth factorGO:00708481890.022
membrane depolarizationGO:0051899320.022
small gtpase mediated signal transductionGO:0007264360.022
response to carbohydrateGO:00097431830.022
cellular cation homeostasisGO:00300031800.022
eye morphogenesisGO:004859240.022
regulation of neurogenesisGO:00507672470.021
cell morphogenesis involved in differentiationGO:00009041190.021
negative regulation of cellular component organizationGO:0051129830.021
positive regulation of transportGO:00510502450.021
regulation of fat cell proliferationGO:007034410.021
positive regulation of cellular component organizationGO:00511302000.021
cytolysisGO:001983540.021
negative regulation of nitrogen compound metabolic processGO:00511721610.020
negative regulation of rna biosynthetic processGO:19026791180.020
developmental growthGO:00485891000.020
Rat
heart morphogenesisGO:000300730.020
synaptic transmission glutamatergicGO:0035249330.020
Rat
signal transduction by phosphorylationGO:00230141440.020
neuron fate commitmentGO:004866340.020
glial cell differentiationGO:0010001650.020
potassium ion transportGO:0006813970.020
cell morphogenesis involved in neuron differentiationGO:00486671060.020
glutamate receptor signaling pathwayGO:0007215430.020
circulatory system processGO:00030131830.019
Rat
optic nerve developmentGO:002155430.019
specification of organ identityGO:001009220.019
regulation of calcium ion transportGO:0051924770.019
multicellular organism growthGO:003526410.019
positive regulation of cell communicationGO:00106472710.019
locomotory behaviorGO:0007626150.019
regulation of camp biosynthetic processGO:0030817380.019
response to atpGO:0033198130.019
regulation of protein metabolic processGO:00512462890.019
sequestering of metal ionGO:005123890.019
positive regulation of organic acid transportGO:0032892220.019
cellular metal ion homeostasisGO:00068751720.018
carbohydrate derivative biosynthetic processGO:19011371240.018
regulation of striated muscle contractionGO:0006942210.018
neuropeptide signaling pathwayGO:0007218290.018
positive regulation of cellular amine metabolic processGO:003324030.018
inflammatory responseGO:00069541500.018
organ inductionGO:000175910.018
purine nucleotide metabolic processGO:00061632290.018
glutamate secretionGO:0014047190.017
regulation of cytokine productionGO:0001817560.017
positive regulation of developmental processGO:00510942830.017
protein phosphorylationGO:00064683450.017
nerve developmentGO:0021675110.017
axon ensheathmentGO:0008366400.017
negative regulation of apoptotic processGO:00430661810.017
cell proliferation in forebrainGO:002184630.017
dicarboxylic acid transportGO:0006835340.017
heart contractionGO:0060047570.017
nucleotide biosynthetic processGO:0009165980.017
regulation of organic acid transportGO:0032890350.017
regulation of anatomical structure sizeGO:00900661350.017
Rat
cellular lipid metabolic processGO:00442552080.017
sequestering of calcium ionGO:005120880.017
divalent inorganic cation transportGO:00725111340.017
protein heterooligomerizationGO:0051291890.017
positive regulation of camp metabolic processGO:0030816310.017
negative regulation of neuron differentiationGO:0045665620.017
positive regulation of rna biosynthetic processGO:19026801970.017
positive regulation of erk1 and erk2 cascadeGO:0070374290.017
agingGO:00075682410.016
cellular protein localizationGO:00346131220.016
mechanoreceptor differentiationGO:004249020.016
neurotransmitter uptakeGO:000150430.016
striated muscle contractionGO:0006941440.016
nucleotide metabolic processGO:00091172790.016
cell cell signaling involved in cell fate commitmentGO:004516820.016
negative regulation of signal transductionGO:0009968830.016
cellular component movementGO:00069282480.016
cell type specific apoptotic processGO:00972851340.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
regulation of growthGO:00400081050.016
Rat
negative regulation of signalingGO:00230571570.016
nucleoside phosphate biosynthetic processGO:19012931020.016
negative regulation of cellular metabolic processGO:00313242810.016
divalent metal ion transportGO:00708381320.015
regulation of cellular protein metabolic processGO:00322682670.015
regulation of cell projection organizationGO:00313441750.015
positive regulation of protein phosphorylationGO:00019341350.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
embryonic pattern specificationGO:000988010.015
negative regulation of transportGO:00510511360.015
cytosolic calcium ion homeostasisGO:00514801400.015
ribonucleotide metabolic processGO:00092592310.015
ribonucleotide biosynthetic processGO:0009260850.015
fat cell proliferationGO:007034120.015
positive regulation of protein modification processGO:00314011420.015
regulation of neurotransmitter uptakeGO:005158010.015
response to nutrient levelsGO:00316673700.015
protein localizationGO:00081041910.015
positive regulation of protein metabolic processGO:00512471780.015
negative regulation of biosynthetic processGO:00098901680.015
oxoacid metabolic processGO:00434362900.015
enzyme linked receptor protein signaling pathwayGO:00071671160.014
regulation of cell developmentGO:00602842630.014
regulation of ion homeostasisGO:2000021630.014
regulation of cation channel activityGO:2001257230.014
positive regulation of synaptic transmissionGO:0050806620.014
neuron projection morphogenesisGO:00488121220.014
cation homeostasisGO:00550801950.014
purine ribonucleotide biosynthetic processGO:0009152810.014
calcium ion transmembrane transportGO:0070588700.014
blood circulationGO:00080151830.014
Rat
amine transportGO:0015837570.014
ribose phosphate metabolic processGO:00196932350.014
sensory organ developmentGO:0007423740.014
purine nucleotide biosynthetic processGO:0006164830.014
carbohydrate derivative metabolic processGO:19011353460.014
regulation of heart contractionGO:0008016480.013
oxidation reduction processGO:00551143040.013
positive regulation of intracellular signal transductionGO:19025331380.013
circadian regulation of gene expressionGO:003292230.013
regulation of nucleotide biosynthetic processGO:0030808470.013
response to extracellular stimulusGO:00099913800.013
positive regulation of secretionGO:00510471400.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
peptidyl amino acid modificationGO:00181931260.013
negative regulation of cell deathGO:00605482290.013
apoptotic processGO:00069153810.013
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.013
positive regulation of cell differentiationGO:00455972170.013
neurotransmitter transportGO:0006836420.013
regulation of developmental growthGO:0048638450.013
Rat
regulation of camp metabolic processGO:0030814430.013
inner ear morphogenesisGO:004247210.013
regulation of cellular localizationGO:00603412630.013
cyclic nucleotide biosynthetic processGO:0009190630.013
negative regulation of protein metabolic processGO:00512481140.012
response to biotic stimulusGO:00096072260.012
single organism biosynthetic processGO:00447113420.012
regulation of system processGO:00440572080.012
regulation of cellular ketone metabolic processGO:0010565270.012
gamma aminobutyric acid transportGO:001581280.012
regulation of gamma aminobutyric acid secretionGO:001405260.012
response to cgmpGO:007030530.012
regulation of defecationGO:200029210.012
vesicle mediated transportGO:00161921810.012
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.012
neuromuscular processGO:005090520.012
positive regulation of gamma aminobutyric acid secretionGO:001405440.012
ras protein signal transductionGO:0007265290.012
regulation of neuronal synaptic plasticityGO:0048168310.012
cellular ion homeostasisGO:00068731840.012
camp metabolic processGO:0046058630.012
negative regulation of programmed cell deathGO:00430691830.012
regulation of response to stressGO:00801341260.012
Rat
regulation of calcium ion transmembrane transportGO:1903169180.012
negative regulation of transporter activityGO:0032410130.012
amine metabolic processGO:0009308380.012
sarcoplasmic reticulum calcium ion transportGO:007029680.012
actin filament based movementGO:0030048160.011
cellular ketone metabolic processGO:0042180510.011
positive regulation of cell activationGO:0050867340.011
regulation of blood vessel sizeGO:0050880890.011
Rat
multicellular organism reproductionGO:00325042330.011
negative regulation of ion transmembrane transportGO:0034766160.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.011
peptide transportGO:0015833970.011
cell projection morphogenesisGO:00488581230.011
purine containing compound metabolic processGO:00725212530.011
coronary vasculature morphogenesisGO:006097730.011
positive regulation of amine transportGO:0051954260.011
organic cyclic compound catabolic processGO:19013611750.011
positive regulation of cardiac muscle contractionGO:006045240.011
positive regulation of nervous system developmentGO:00519621780.011
positive regulation of cytolysisGO:004591910.011
response to glucoseGO:00097491360.011
positive regulation of cardiac muscle cell proliferationGO:006004540.011
synaptic growth at neuromuscular junctionGO:005112410.011
cytoplasmic transportGO:00164821150.011
regulation of canonical wnt signaling pathwayGO:006082840.011
retina development in camera type eyeGO:0060041270.011
reproductionGO:00000032450.011
cognitionGO:0050890920.011
response to other organismGO:00517072200.011
synaptic transmission gabaergicGO:0051932220.011
secretion by cellGO:00329402480.010
positive regulation of cell developmentGO:00107201760.010
response to lipopolysaccharideGO:00324961910.010
response to cytokineGO:00340972150.010
response to osmotic stressGO:0006970420.010
respiratory gaseous exchangeGO:000758540.010
cellular macromolecule localizationGO:00707271220.010
response to histamineGO:003477630.010
positive regulation of potassium ion transmembrane transportGO:190138140.010
regulation of cardiac muscle contractionGO:0055117170.010
response to oxygen levelsGO:00704822650.010

P2rx6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.138
disease of anatomical entityDOID:700.138
sensory system diseaseDOID:005015500.041
nervous system diseaseDOID:86300.041
disease of metabolismDOID:001466700.022
eye and adnexa diseaseDOID:149200.015
eye diseaseDOID:561400.015
acquired metabolic diseaseDOID:006015800.014
nutrition diseaseDOID:37400.014
muscular diseaseDOID:008000000.013
overnutritionDOID:65400.013
obesityDOID:997000.013
connective tissue diseaseDOID:6500.013
myopathyDOID:42300.012
muscle tissue diseaseDOID:6600.012