Rattus norvegicus

16 known processes

Klkb1

kallikrein B, plasma 1

(Aliases: Kalp1,MGC108748,Klk3,KALP15)

Klkb1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.233
monocarboxylic acid metabolic processGO:00327871520.212
cation transportGO:00068123820.211
cellular lipid metabolic processGO:00442552080.198
response to insulinGO:00328681330.186
response to estrogenGO:00436272320.184
carboxylic acid transportGO:00469421150.159
response to metal ionGO:00100382530.157
organic substance catabolic processGO:19015753160.154
response to corticosteroidGO:00319602350.151
carboxylic acid metabolic processGO:00197522890.141
cellular response to glucocorticoid stimulusGO:0071385680.139
triglyceride metabolic processGO:0006641210.139
organic anion transportGO:00157111320.136
regulation of cellular component organizationGO:00511283680.135
anatomical structure morphogenesisGO:00096532980.133
cellular amino acid metabolic processGO:00065201070.126
lipid metabolic processGO:00066292830.122
agingGO:00075682410.121
response to glucocorticoidGO:00513842230.120
single organism reproductive processGO:00447022970.115
metal ion transportGO:00300012890.113
secretionGO:00469033070.106
response to acid chemicalGO:00011012220.105
regulation of secretion by cellGO:19035302080.103
organic acid transportGO:00158491160.101
oxoacid metabolic processGO:00434362900.099
liver developmentGO:0001889900.099
response to peptide hormoneGO:00434342780.093
alkaloid metabolic processGO:000982030.091
reproductive processGO:00224143720.091
gland developmentGO:00487321550.090
negative regulation of serine type endopeptidase activityGO:190000410.090
halogenated hydrocarbon metabolic processGO:004219740.090
oxidation reduction processGO:00551143040.090
monocarboxylic acid transportGO:0015718520.087
transmembrane transportGO:00550854120.085
positive regulation of multicellular organismal processGO:00512403870.084
response to extracellular stimulusGO:00099913800.080
multi organism reproductive processGO:00447032620.078
organonitrogen compound biosynthetic processGO:19015661670.078
cellular homeostasisGO:00197252520.077
chemical homeostasisGO:00488782920.072
catabolic processGO:00090563510.072
trichloroethylene metabolic processGO:001897910.072
organonitrogen compound catabolic processGO:19015651790.070
positive regulation of transportGO:00510502450.070
naphthalene metabolic processGO:001893120.069
renal system processGO:0003014400.067
acylglycerol metabolic processGO:0006639210.067
circulatory system processGO:00030131830.067
response to inorganic substanceGO:00100353770.066
cellular response to lipidGO:00713962010.066
response to herbicideGO:0009635160.065
anion transportGO:00068201780.065
multicellular organism growthGO:003526410.063
regulation of cellular localizationGO:00603412630.062
cellular ketone metabolic processGO:0042180510.062
response to carbohydrateGO:00097431830.062
regulation of secretionGO:00510462240.062
blood circulationGO:00080151830.062
brain developmentGO:00074202470.062
neutral lipid metabolic processGO:0006638210.060
regulation of hormone levelsGO:00108171870.056
cellular amine metabolic processGO:0044106380.056
phenol containing compound metabolic processGO:0018958300.056
terpenoid metabolic processGO:0006721370.056
cellular catabolic processGO:00442482950.054
amine metabolic processGO:0009308380.054
divalent inorganic cation transportGO:00725111340.053
cellular response to insulin stimulusGO:0032869810.053
steroid biosynthetic processGO:0006694480.053
protein complex subunit organizationGO:00718223020.052
cellular component biogenesisGO:00440853680.051
regulation of cellular ketone metabolic processGO:0010565270.050
positive regulation of cellular component organizationGO:00511302000.049
lipid transportGO:0006869610.048
macromolecular complex subunit organizationGO:00439333390.048
developmental process involved in reproductionGO:00030061590.047
telencephalon developmentGO:0021537620.046
regulation of body fluid levelsGO:0050878900.046
Human Rat
protein complex biogenesisGO:00702712630.046
response to estradiolGO:00323551640.045
response to monosaccharideGO:00342841590.045
positive regulation of cell projection organizationGO:00313461110.045
positive regulation of phosphate metabolic processGO:00459372620.045
regulation of anatomical structure sizeGO:00900661350.044
cellular component movementGO:00069282480.044
response to woundingGO:00096112540.044
Human Rat
cellular response to peptide hormone stimulusGO:00713751200.043
sexual reproductionGO:00199531480.043
synaptic transmissionGO:00072682350.042
cell cell signalingGO:00072673350.042
regulation of response to external stimulusGO:00321011060.041
Human
regulation of cellular amine metabolic processGO:003323880.041
organic acid biosynthetic processGO:0016053830.041
small molecule catabolic processGO:0044282590.040
regulation of protein maturationGO:1903317500.039
regulation of cellular amino acid metabolic processGO:000652120.039
nitrogen compound transportGO:00717052290.039
secretion by cellGO:00329402480.039
fatty acid metabolic processGO:0006631990.038
response to toxic substanceGO:00096361330.038
cellular sodium ion homeostasisGO:000688340.038
phthalate metabolic processGO:001896380.037
hepaticobiliary system developmentGO:0061008900.037
macromolecule localizationGO:00330362520.037
macromolecular complex assemblyGO:00650032730.036
negative regulation of metabolic processGO:00098923310.036
response to ethanolGO:00454711620.036
organic hydroxy compound metabolic processGO:19016151150.036
heart developmentGO:0007507720.036
response to transition metal nanoparticleGO:19902671220.036
negative regulation of macromolecule metabolic processGO:00106052600.036
regulation of extracellular matrix constituent secretionGO:000333020.035
regulation of blood pressureGO:0008217830.035
isoprenoid metabolic processGO:0006720450.035
cellular calcium ion homeostasisGO:00068741600.035
cellular chemical homeostasisGO:00550822470.034
regulation of ion transportGO:00432692450.034
positive regulation of molecular functionGO:00440932300.034
nucleobase containing small molecule metabolic processGO:00550863160.033
lipid localizationGO:0010876620.033
protein complex assemblyGO:00064612630.033
central nervous system developmentGO:00074173110.033
regulation of blood vessel sizeGO:0050880890.033
multi multicellular organism processGO:00447061380.033
locomotionGO:00400112370.032
regulation of blood circulationGO:19035221100.032
cellular response to metal ionGO:0071248550.032
response to nutrient levelsGO:00316673700.032
negative regulation of cellular metabolic processGO:00313242810.032
regulation of tube sizeGO:0035150890.032
organic cyclic compound catabolic processGO:19013611750.032
negative regulation of protein metabolic processGO:00512481140.032
response to peptideGO:19016522920.032
positive regulation of cell proliferationGO:00082842490.032
regulation of hormone secretionGO:00468831060.031
reactive nitrogen species metabolic processGO:200105710.031
vesicle mediated transportGO:00161921810.031
neurological system processGO:00508772190.031
neuron developmentGO:00486662860.031
organelle localizationGO:0051640550.031
acid secretionGO:0046717480.030
alpha amino acid catabolic processGO:1901606200.030
single organism catabolic processGO:00447122830.030
organophosphate metabolic processGO:00196373700.030
cellular cation homeostasisGO:00300031800.030
neuron projection developmentGO:00311752730.030
regulation of programmed cell deathGO:00430673410.030
organic acid catabolic processGO:0016054490.030
response to electrical stimulusGO:0051602560.030
positive regulation of ion transportGO:0043270940.029
coagulationGO:0050817280.029
Human Rat
steroid metabolic processGO:0008202730.029
positive regulation of cellular amine metabolic processGO:003324030.029
purine nucleotide metabolic processGO:00061632290.029
bile acid biosynthetic processGO:000669930.029
regulation of cell developmentGO:00602842630.029
behaviorGO:00076102050.028
lipid biosynthetic processGO:00086101280.028
growthGO:00400071650.028
positive regulation of cellular amino acid metabolic processGO:004576410.028
hormone transportGO:00099141210.028
protein oligomerizationGO:00512591910.028
cellular response to hexose stimulusGO:0071331650.028
single organism biosynthetic processGO:00447113420.028
epoxygenase p450 pathwayGO:001937310.028
regulation of cell proliferationGO:00421273590.027
amide transportGO:00428861050.027
response to ionizing radiationGO:0010212590.027
cellular ion homeostasisGO:00068731840.027
ion transmembrane transportGO:00342203650.027
negative regulation of growthGO:0045926370.027
positive regulation of secretionGO:00510471400.027
positive regulation of extracellular matrix constituent secretionGO:000333120.027
programmed cell deathGO:00125013920.027
positive regulation of neuron differentiationGO:00456661260.027
regulation of reactive oxygen species biosynthetic processGO:190342650.026
cellular response to stressGO:00335542690.026
icosanoid metabolic processGO:0006690380.026
positive regulation of neuron projection developmentGO:0010976990.026
nucleoside phosphate metabolic processGO:00067532830.026
dopamine metabolic processGO:0042417120.026
apoptotic processGO:00069153810.026
carboxylic acid catabolic processGO:0046395490.026
divalent metal ion transportGO:00708381320.026
neuron differentiationGO:00301823680.026
regulation of behaviorGO:0050795610.025
regulation of multicellular organismal developmentGO:20000263760.025
regulation of peptide hormone secretionGO:0090276800.025
homeostatic processGO:00425923310.025
response to mechanical stimulusGO:00096121340.025
cellular component assemblyGO:00226073600.025
positive regulation of extracellular matrix organizationGO:190305540.025
cellular response to corticosteroid stimulusGO:0071384690.025
regulation of growthGO:00400081050.025
ribonucleotide metabolic processGO:00092592310.025
cellular metal ion homeostasisGO:00068751720.024
extracellular matrix constituent secretionGO:007027840.024
response to amineGO:0014075460.024
long chain fatty acid metabolic processGO:0001676320.024
regulation of cellular component movementGO:00512701500.024
response to glucoseGO:00097491360.024
blood vessel morphogenesisGO:0048514580.024
sensory perceptionGO:00076001010.024
fatty acid derivative metabolic processGO:1901568380.024
cellular response to nitrogen compoundGO:19016992100.024
reactive oxygen species biosynthetic processGO:190340980.024
male sex differentiationGO:0046661640.024
regulation of protein metabolic processGO:00512462890.023
amino acid transportGO:0006865700.023
response to corticosteroneGO:0051412400.023
pyridine containing compound metabolic processGO:0072524320.023
alpha amino acid metabolic processGO:1901605710.023
organelle organizationGO:00069962660.023
cellular response to cytokine stimulusGO:00713451270.023
excretionGO:0007588240.023
c21 steroid hormone metabolic processGO:0008207140.023
artery smooth muscle contractionGO:001482440.022
positive regulation of cell developmentGO:00107201760.022
aromatic amino acid family catabolic processGO:000907470.022
regulation of hydrolase activityGO:00513361430.022
regulation of catalytic activityGO:00507903040.022
diterpenoid metabolic processGO:0016101330.022
head developmentGO:00603222470.022
calcium ion transportGO:00068161310.022
carbohydrate derivative biosynthetic processGO:19011371240.022
monovalent inorganic cation transportGO:00156721720.022
cellular response to hormone stimulusGO:00328702470.022
positive regulation of secretion by cellGO:19035321280.022
regulation of protein phosphorylationGO:00019321830.022
regulation of neuron differentiationGO:00456642080.022
positive regulation of nitrogen compound metabolic processGO:00511733340.022
regulation of serine type peptidase activityGO:190257110.022
regulation of cell growthGO:0001558850.022
regulation of apoptotic processGO:00429813350.022
immune system processGO:00023762040.021
cellular nitrogen compound catabolic processGO:00442701630.021
cation homeostasisGO:00550801950.021
negative regulation of cellular protein metabolic processGO:00322691060.021
organic hydroxy compound transportGO:0015850770.021
negative regulation of peptidase activityGO:0010466380.021
response to alkaloidGO:00432791320.021
gamete generationGO:00072761240.021
energy derivation by oxidation of organic compoundsGO:0015980460.021
negative regulation of gene expressionGO:00106291990.021
muscle system processGO:00030121150.021
response to radiationGO:00093141370.020
response to mercury ionGO:0046689150.020
female pregnancyGO:00075651220.020
response to amphetamineGO:0001975250.020
tonic smooth muscle contractionGO:001482040.020
regulation of system processGO:00440572080.020
vascular process in circulatory systemGO:0003018960.020
regulation of cell projection organizationGO:00313441750.020
peptide transportGO:0015833970.020
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.020
regulation of catabolic processGO:00098941130.020
isoquinoline alkaloid metabolic processGO:003307620.020
cellular response to endogenous stimulusGO:00714953770.020
phenol containing compound biosynthetic processGO:004618990.020
regulation of transmembrane transportGO:00347621220.019
heterocycle catabolic processGO:00467001670.019
circulatory system developmentGO:00723591340.019
negative regulation of serine type peptidase activityGO:190257210.019
sex differentiationGO:00075481130.019
lipid catabolic processGO:0016042460.019
response to oxidative stressGO:00069791860.019
wound healingGO:00420601220.019
Human Rat
regulation of signal transductionGO:00099663180.019
positive regulation of cell differentiationGO:00455972170.019
cellular response to growth factor stimulusGO:00713631620.019
nucleotide metabolic processGO:00091172790.019
response to decreased oxygen levelsGO:00362932370.018
aromatic compound catabolic processGO:00194391680.018
regulation of neuron projection developmentGO:00109751610.018
cardiovascular system developmentGO:00723581340.018
establishment of organelle localizationGO:0051656370.018
response to cesium ionGO:001016420.018
regulation of peptide secretionGO:0002791820.018
cell projection organizationGO:00300303020.018
tissue developmentGO:00098882520.018
multicellular organismal reproductive processGO:00486092330.018
regulation of protein processingGO:0070613500.018
negative regulation of cardiac muscle tissue developmentGO:005502630.018
response to oxygen levelsGO:00704822650.018
positive regulation of catabolic processGO:0009896780.018
positive regulation of blood coagulationGO:003019440.018
ras protein signal transductionGO:0007265290.018
regulation of molecular functionGO:00650093980.018
cell motilityGO:00488702020.018
positive regulation of developmental processGO:00510942830.018
protein phosphorylationGO:00064683450.018
carbohydrate homeostasisGO:0033500750.018
hormone biosynthetic processGO:0042446250.018
response to hexoseGO:00097461440.017
positive regulation of cellular biosynthetic processGO:00313282950.017
regulation of phosphorus metabolic processGO:00511743490.017
renin angiotensin regulation of aldosterone productionGO:000201830.017
reproductionGO:00000032450.017
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.017
defense responseGO:00069521940.017
glucose homeostasisGO:0042593750.017
negative regulation of organ growthGO:004662130.017
regulation of purine nucleotide metabolic processGO:19005421150.017
organic hydroxy compound biosynthetic processGO:1901617510.017
regulation of systemic arterial blood pressureGO:0003073300.017
metal ion homeostasisGO:00550651860.017
response to vitamin b6GO:003451610.017
male gamete generationGO:0048232990.017
response to chromateGO:004668730.017
response to external biotic stimulusGO:00432072210.017
response to foodGO:0032094270.017
insecticide metabolic processGO:001714340.017
regulation of peptide transportGO:0090087870.017
response to bacteriumGO:00096172000.017
response to vitaminGO:00332731310.016
response to growth factorGO:00708481890.016
nicotine metabolic processGO:001893310.016
androgen metabolic processGO:0008209140.016
organ morphogenesisGO:0009887750.016
positive regulation of hydrolase activityGO:0051345860.016
reactive oxygen species metabolic processGO:0072593370.016
smooth muscle cell proliferationGO:0048659770.016
positive regulation of nervous system developmentGO:00519621780.016
positive regulation of catalytic activityGO:00430851840.016
cellular response to external stimulusGO:00714961180.016
small molecule biosynthetic processGO:00442831240.016
xenobiotic metabolic processGO:0006805190.016
naphthalene containing compound metabolic processGO:009042020.016
reproductive structure developmentGO:00486081280.016
positive regulation of phosphorus metabolic processGO:00105622620.016
actin filament based processGO:0030029860.015
catecholamine metabolic processGO:0006584190.015
brain renin angiotensin systemGO:000203530.015
actin crosslink formationGO:005176430.015
cardiac chamber developmentGO:000320510.015
response to fungicideGO:0060992200.015
response to hypoxiaGO:00016662310.015
regulation of locomotionGO:00400121480.015
blood coagulationGO:0007596260.015
Human Rat
peptide hormone secretionGO:0030072840.015
carboxylic acid biosynthetic processGO:0046394830.015
response to reactive oxygen speciesGO:00003021200.015
spermatogenesisGO:0007283990.015
cation transmembrane transportGO:00986552630.015
protein secretionGO:0009306340.015
positive regulation of response to stimulusGO:00485842850.015
multicellular organism reproductionGO:00325042330.015
signal transduction by phosphorylationGO:00230141440.015
intracellular signal transductionGO:00355563140.015
regulation of reactive oxygen species metabolic processGO:2000377260.015
regulation of response to stressGO:00801341260.014
Human
regulation of cellular protein metabolic processGO:00322682670.014
angiotensin mediated drinking behaviorGO:000305120.014
xenobiotic catabolic processGO:004217870.014
cellular response to oxygen containing compoundGO:19017013860.014
glycerolipid metabolic processGO:0046486670.014
cellular response to organonitrogen compoundGO:00714171970.014
cellular response to steroid hormone stimulusGO:0071383930.014
establishment of vesicle localizationGO:0051650310.014
mesoderm formationGO:000170710.014
linoleic acid metabolic processGO:004365140.014
response to cytokineGO:00340972150.014
positive regulation of nucleotide metabolic processGO:0045981910.014
hemostasisGO:0007599260.014
Human Rat
cellular response to organic cyclic compoundGO:00714072020.014
cellular response to abiotic stimulusGO:0071214850.014
localization of cellGO:00516742020.014
bile acid and bile salt transportGO:0015721120.014
fibrinolysisGO:004273020.014
Human
positive regulation of fatty acid beta oxidationGO:003200040.014
regulation of synaptic transmissionGO:00508041410.014
regulation of serine type endopeptidase activityGO:190000310.014
regulation of cyclic nucleotide metabolic processGO:0030799510.014
regulation of neurogenesisGO:00507672470.014
cellular hormone metabolic processGO:0034754490.014
organophosphate biosynthetic processGO:00904071430.014
macromolecule catabolic processGO:0009057580.014
exocytosisGO:0006887600.014
regulation of cell differentiationGO:00455953200.014
developmental growthGO:00485891000.014
positive regulation of lipid catabolic processGO:005099640.014
forebrain developmentGO:0030900980.014
response to ketoneGO:19016541820.014
unsaturated fatty acid metabolic processGO:0033559390.013
purine ribonucleotide metabolic processGO:00091502270.013
catecholamine biosynthetic processGO:004242390.013
regulation of phosphate metabolic processGO:00192203490.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
regulation of nervous system developmentGO:00519602640.013
negative regulation of cell deathGO:00605482290.013
catechol containing compound biosynthetic processGO:000971390.013
vasoconstrictionGO:0042310540.013
inflammatory responseGO:00069541500.013
response to xenobiotic stimulusGO:0009410230.013
regulation of dendrite developmentGO:0050773590.013
retinoid metabolic processGO:0001523240.013
positive regulation of homeostatic processGO:0032846490.013
single organism behaviorGO:00447081300.013
androgen biosynthetic processGO:0006702100.013
negative regulation of cardiac muscle cell proliferationGO:006004420.013
pallium developmentGO:0021543420.013
positive regulation of hormone secretionGO:0046887650.013
sterol catabolic processGO:001612710.013
divalent inorganic cation homeostasisGO:00725071650.013
response to activityGO:0014823730.013
negative regulation of signalingGO:00230571570.013
catechol containing compound metabolic processGO:0009712190.013
cellular response to inorganic substanceGO:0071241650.013
cellular response to mechanical stimulusGO:0071260480.012
vasodilationGO:0042311440.012
proteolysisGO:00065081750.012
Rat
positive regulation of blood circulationGO:1903524650.012
response to gonadotropinGO:0034698340.012
signal releaseGO:00230611450.012
regulation of transcription dna templatedGO:00063553740.012
insulin secretionGO:0030073690.012
regulation of muscle system processGO:0090257790.012
negative regulation of molecular functionGO:00440921330.012
response to starvationGO:0042594590.012
monocarboxylic acid biosynthetic processGO:0072330480.012
cell activationGO:0001775970.012
chlorinated hydrocarbon metabolic processGO:004219640.012
regulation of wound healingGO:0061041140.012
Human
negative regulation of cardiac muscle tissue growthGO:005502230.012
negative regulation of heart growthGO:006111730.012
axis specificationGO:000979840.012
ribose phosphate metabolic processGO:00196932350.012
negative regulation of protein maturationGO:1903318470.012
regulation of proteolysisGO:0030162660.012
sodium ion homeostasisGO:0055078230.012
gonad developmentGO:00084061040.012
carbohydrate derivative metabolic processGO:19011353460.012
positive regulation of biosynthetic processGO:00098913190.012
regulation of insulin secretionGO:0050796650.012
cellular component morphogenesisGO:00329891550.012
regulation of anatomical structure morphogenesisGO:00226031410.011
cyclic nucleotide metabolic processGO:0009187800.011
positive regulation of neurogenesisGO:00507691650.011
regulation of calcium ion transportGO:0051924770.011
calcium ion homeostasisGO:00550741620.011
development of primary sexual characteristicsGO:00451371070.011
response to lead ionGO:0010288330.011
single organism organelle organizationGO:19025891800.011
regulation of synaptic plasticityGO:0048167700.011
renal system process involved in regulation of systemic arterial blood pressureGO:0003071140.011
positive regulation of locomotionGO:00400171020.011
purine containing compound metabolic processGO:00725212530.011
cellular response to alcoholGO:0097306870.011
amine transportGO:0015837570.011
lipid storageGO:001991510.011
regulation of ion transmembrane transportGO:00347651210.011
reproductive system developmentGO:00614581280.011
positive regulation of blood pressureGO:0045777310.011
positive regulation of hemostasisGO:190004840.011
heart morphogenesisGO:000300730.011
neuron projection morphogenesisGO:00488121220.011
alcohol metabolic processGO:0006066770.011
cellular response to glucose stimulusGO:0071333650.011
cellular amino acid catabolic processGO:0009063210.011
multicellular organismal signalingGO:0035637440.011
regulation of membrane potentialGO:00423911100.011
negative regulation of catalytic activityGO:00430861030.011
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
rna localizationGO:000640340.011
canalicular bile acid transportGO:001572250.010
response to triglycerideGO:003401430.010
hormone secretionGO:00468791150.010
synaptic transmission glutamatergicGO:0035249330.010
negative regulation of protein processingGO:0010955470.010
negative regulation of programmed cell deathGO:00430691830.010
protein processingGO:0016485680.010
Human
maintenance of locationGO:0051235170.010
positive regulation of purine nucleotide metabolic processGO:1900544910.010
purine ribonucleotide biosynthetic processGO:0009152810.010
response to lipopolysaccharideGO:00324961910.010
cellular response to monosaccharide stimulusGO:0071326670.010
transmission of nerve impulseGO:0019226420.010
regulation of vasodilationGO:0042312360.010
cellular macromolecular complex assemblyGO:0034622580.010
regulation of mapk cascadeGO:00434081160.010
cellular response to carbohydrate stimulusGO:0071322720.010

Klkb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.028
cardiovascular system diseaseDOID:128700.017
vascular diseaseDOID:17800.017
disease of anatomical entityDOID:700.017
acquired metabolic diseaseDOID:006015800.015
inherited metabolic disorderDOID:65500.012