Rattus norvegicus

35 known processes

Eif5a

eukaryotic translation initiation factor 5A

(Aliases: MGC124873)

Eif5a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to cytokineGO:00340972150.487
tissue developmentGO:00098882520.295
regulation of cellular component organizationGO:00511283680.270
cellular component assemblyGO:00226073600.263
macromolecular complex subunit organizationGO:00439333390.228
cellular response to cytokine stimulusGO:00713451270.224
cellular component biogenesisGO:00440853680.194
regulation of phosphate metabolic processGO:00192203490.169
response to purine containing compoundGO:00140741260.161
positive regulation of phosphate metabolic processGO:00459372620.152
programmed cell deathGO:00125013920.140
regulation of cellular protein metabolic processGO:00322682670.114
organophosphate biosynthetic processGO:00904071430.113
macromolecular complex assemblyGO:00650032730.108
receptor internalizationGO:0031623140.103
organic substance catabolic processGO:19015753160.098
cell cycleGO:00070491010.094
intracellular transportGO:00469071850.094
regulation of cell developmentGO:00602842630.092
protein complex subunit organizationGO:00718223020.090
positive regulation of phosphorus metabolic processGO:00105622620.089
cell cycle processGO:0022402570.087
cardiovascular system developmentGO:00723581340.081
anatomical structure morphogenesisGO:00096532980.080
cellular macromolecular complex assemblyGO:0034622580.079
cell projection organizationGO:00300303020.077
regulation of cellular catabolic processGO:00313291010.075
regulation of organelle organizationGO:0033043800.072
positive regulation of response to stimulusGO:00485842850.070
organonitrogen compound biosynthetic processGO:19015661670.069
positive regulation of cellular component organizationGO:00511302000.068
positive regulation of cellular biosynthetic processGO:00313282950.065
positive regulation of biosynthetic processGO:00098913190.065
regulation of phosphorus metabolic processGO:00511743490.065
purine containing compound metabolic processGO:00725212530.064
negative regulation of metabolic processGO:00098923310.060
positive regulation of cellular component biogenesisGO:0044089550.060
regulation of meiotic cell cycleGO:005144530.060
protein phosphorylationGO:00064683450.059
locomotionGO:00400112370.057
protein complex assemblyGO:00064612630.057
nucleoside phosphate metabolic processGO:00067532830.057
regulation of transcription dna templatedGO:00063553740.057
polyamine biosynthetic processGO:000659640.057
rna biosynthetic processGO:00327743800.057
dephosphorylationGO:0016311980.056
generation of precursor metabolites and energyGO:0006091620.055
macromolecule localizationGO:00330362520.053
tube developmentGO:0035295890.052
protein complex biogenesisGO:00702712630.051
apoptotic processGO:00069153810.050
regulation of protein phosphorylationGO:00019321830.049
muscle tissue morphogenesisGO:006041510.049
posttranscriptional regulation of gene expressionGO:0010608370.049
regulation of protein modification processGO:00313991940.048
rna metabolic processGO:00160704060.046
purine ribonucleotide metabolic processGO:00091502270.046
circulatory system developmentGO:00723591340.045
positive regulation of protein metabolic processGO:00512471780.045
positive regulation of nitrogen compound metabolic processGO:00511733340.045
positive regulation of catalytic activityGO:00430851840.044
positive regulation of protein modification processGO:00314011420.043
nucleic acid templated transcriptionGO:00976593790.043
heart developmentGO:0007507720.043
regulation of programmed cell deathGO:00430673410.043
ribonucleotide metabolic processGO:00092592310.043
regulation of neuron differentiationGO:00456642080.042
hematopoietic progenitor cell differentiationGO:000224420.041
positive regulation of phosphorylationGO:00423271770.040
cellular protein complex assemblyGO:0043623440.040
amine metabolic processGO:0009308380.040
regulation of apoptotic processGO:00429813350.039
positive regulation of nucleobase containing compound metabolic processGO:00459353190.038
regulation of neurogenesisGO:00507672470.038
negative regulation of apoptotic processGO:00430661810.038
nucleocytoplasmic transportGO:0006913480.038
neuron differentiationGO:00301823680.037
purine nucleotide catabolic processGO:00061951360.037
negative regulation of cell deathGO:00605482290.037
regulation of protein polymerizationGO:0032271190.036
single organism organelle organizationGO:19025891800.036
homeostatic processGO:00425923310.036
neuron projection developmentGO:00311752730.036
cellular response to growth factor stimulusGO:00713631620.035
positive regulation of cell deathGO:00109421840.035
positive regulation of organelle organizationGO:0010638480.035
nucleoside phosphate biosynthetic processGO:19012931020.034
cellular amine metabolic processGO:0044106380.034
regulation of multicellular organismal developmentGO:20000263760.032
regulation of nucleotide metabolic processGO:00061401170.032
organophosphate metabolic processGO:00196373700.032
lipid localizationGO:0010876620.031
multi organism reproductive processGO:00447032620.031
modification dependent macromolecule catabolic processGO:0043632140.031
positive regulation of gene expressionGO:00106282440.031
endocytosisGO:0006897840.031
regulation of nervous system developmentGO:00519602640.031
positive regulation of apoptotic processGO:00430651540.031
eye developmentGO:0001654500.030
positive regulation of nucleotide metabolic processGO:0045981910.029
regulation of purine nucleotide metabolic processGO:19005421150.028
cellular homeostasisGO:00197252520.028
agingGO:00075682410.028
cellular protein catabolic processGO:0044257190.028
regulation of signal transductionGO:00099663180.028
receptor mediated endocytosisGO:0006898420.027
positive regulation of cellular protein metabolic processGO:00322701670.027
protein import into nucleusGO:0006606350.027
ribosomal small subunit biogenesisGO:004227460.027
cytoplasmic transportGO:00164821150.026
negative regulation of nitrogen compound metabolic processGO:00511721610.026
negative regulation of cell developmentGO:0010721820.026
negative regulation of signalingGO:00230571570.026
regulation of phosphorylationGO:00423252480.025
carbohydrate derivative metabolic processGO:19011353460.025
single organism reproductive processGO:00447022970.025
tissue morphogenesisGO:0048729220.024
reproductionGO:00000032450.024
positive regulation of signal transductionGO:00099671750.024
purine nucleotide metabolic processGO:00061632290.024
purine ribonucleoside triphosphate metabolic processGO:00092051400.024
nucleotide metabolic processGO:00091172790.024
positive regulation of cell communicationGO:00106472710.024
hematopoietic or lymphoid organ developmentGO:0048534360.024
circadian regulation of gene expressionGO:003292230.024
maintenance of locationGO:0051235170.024
enzyme linked receptor protein signaling pathwayGO:00071671160.023
organic acid transportGO:00158491160.023
positive regulation of programmed cell deathGO:00430681570.023
glycosyl compound metabolic processGO:19016571820.023
transcription dna templatedGO:00063513770.023
cellular catabolic processGO:00442482950.023
lipid storageGO:001991510.023
multicellular organism reproductionGO:00325042330.023
cardiac muscle tissue developmentGO:0048738260.023
muscle cell differentiationGO:0042692520.023
positive regulation of protein phosphorylationGO:00019341350.022
ribose phosphate metabolic processGO:00196932350.022
carboxylic acid metabolic processGO:00197522890.022
positive regulation of endocytosisGO:0045807280.022
positive regulation of hydrolase activityGO:0051345860.022
positive regulation of nucleic acid templated transcriptionGO:19035081970.021
neuron developmentGO:00486662860.021
positive regulation of purine nucleotide biosynthetic processGO:1900373360.021
proteasomal protein catabolic processGO:001049880.021
positive regulation of rna biosynthetic processGO:19026801970.021
cellular component movementGO:00069282480.021
organic cyclic compound catabolic processGO:19013611750.021
multicellular organismal reproductive processGO:00486092330.020
proteolysis involved in cellular protein catabolic processGO:0051603190.020
guanosine containing compound metabolic processGO:1901068740.020
regulation of cellular component biogenesisGO:0044087860.020
positive regulation of developmental processGO:00510942830.020
chemical homeostasisGO:00488782920.020
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:003114510.019
energy derivation by oxidation of organic compoundsGO:0015980460.019
negative regulation of macromolecule metabolic processGO:00106052600.019
heart morphogenesisGO:000300730.019
cell migrationGO:00164771970.019
cell morphogenesisGO:00009021420.019
brain developmentGO:00074202470.019
nucleoside metabolic processGO:00091161790.019
central nervous system developmentGO:00074173110.019
positive regulation of molecular functionGO:00440932300.019
regulation of cell growthGO:0001558850.019
negative regulation of cellular metabolic processGO:00313242810.019
negative regulation of cell communicationGO:00106481580.018
organelle organizationGO:00069962660.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
regulation of arp2 3 complex mediated actin nucleationGO:003431520.018
regulation of catabolic processGO:00098941130.018
positive regulation of transportGO:00510502450.018
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.018
eye morphogenesisGO:004859240.018
regulation of neuron projection developmentGO:00109751610.018
regulation of transferase activityGO:00513381230.018
cell part morphogenesisGO:00329901230.018
oxoacid metabolic processGO:00434362900.018
response to growth factorGO:00708481890.018
response to peptide hormoneGO:00434342780.018
negative regulation of protein modification by small protein conjugation or removalGO:190332140.017
regulation of catalytic activityGO:00507903040.017
purine ribonucleoside metabolic processGO:00461281680.017
growthGO:00400071650.017
cellular chemical homeostasisGO:00550822470.017
translationGO:0006412350.017
nucleoside phosphate catabolic processGO:19012921400.017
pyrimidine nucleoside triphosphate biosynthetic processGO:000914830.017
localization of cellGO:00516742020.017
nucleobase containing small molecule metabolic processGO:00550863160.017
positive regulation of multicellular organismal processGO:00512403870.017
nuclear importGO:0051170350.016
gland developmentGO:00487321550.016
positive regulation of cellular catabolic processGO:0031331710.016
muscle organ morphogenesisGO:004864410.016
regulation of nucleotide catabolic processGO:0030811650.016
cation homeostasisGO:00550801950.016
regulation of cell projection organizationGO:00313441750.016
catabolic processGO:00090563510.015
carbohydrate derivative biosynthetic processGO:19011371240.015
regulation of protein metabolic processGO:00512462890.015
regulation of immune system processGO:00026821230.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316170.015
biological adhesionGO:00226101100.015
sensory organ developmentGO:0007423740.015
organonitrogen compound catabolic processGO:19015651790.015
cellular biogenic amine biosynthetic processGO:004240140.015
peptidyl amino acid modificationGO:00181931260.015
nuclear transportGO:0051169490.015
triglyceride homeostasisGO:007032820.015
pyrimidine nucleoside triphosphate metabolic processGO:000914740.015
cell growthGO:00160491040.015
negative regulation of myeloid cell differentiationGO:004563830.014
regulation of molecular functionGO:00650093980.014
protein oligomerizationGO:00512591910.014
regulation of nucleic acid templated transcriptionGO:19035063800.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
cellular metal ion homeostasisGO:00068751720.014
regulation of nucleoside metabolic processGO:0009118660.014
negative regulation of cell differentiationGO:0045596990.013
positive regulation of gtp catabolic processGO:0033126480.013
positive regulation of transcription dna templatedGO:00458931970.013
regulation of hydrolase activityGO:00513361430.013
regulation of cell differentiationGO:00455953200.013
regulation of cell migrationGO:00303341280.013
cation transportGO:00068123820.013
regulation of locomotionGO:00400121480.013
coenzyme metabolic processGO:0006732860.013
cellular macromolecule catabolic processGO:0044265290.013
er to golgi vesicle mediated transportGO:0006888100.013
cell motilityGO:00488702020.013
regulation of rna metabolic processGO:00512523910.013
intracellular signal transductionGO:00355563140.013
positive regulation of catabolic processGO:0009896780.013
regulation of canonical wnt signaling pathwayGO:006082840.012
positive regulation of actin filament polymerizationGO:003083850.012
ribonucleotide biosynthetic processGO:0009260850.012
regulation of cellular amino acid metabolic processGO:000652120.012
acylglycerol homeostasisGO:005509020.012
amino acid transportGO:0006865700.012
purine nucleoside metabolic processGO:00422781690.012
purine nucleoside biosynthetic processGO:0042451210.012
male gamete generationGO:0048232990.012
regulation of transcription from rna polymerase ii promoterGO:00063572340.012
g protein coupled receptor signaling pathwayGO:00071862420.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
cardiocyte differentiationGO:0035051220.012
cellular amino acid metabolic processGO:00065201070.012
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
developmental growthGO:00485891000.012
cellular response to stressGO:00335542690.012
cellular nitrogen compound catabolic processGO:00442701630.011
regulation of cellular component sizeGO:0032535510.011
regulation of rna biosynthetic processGO:20011413810.011
regulation of cell motilityGO:20001451310.011
organ morphogenesisGO:0009887750.011
regulation of actin nucleationGO:005112520.011
regulation of cellular localizationGO:00603412630.011
spermatogenesisGO:0007283990.011
negative regulation of gene expressionGO:00106291990.011
regulation of ubiquitin protein transferase activityGO:005143810.011
regulation of vesicle mediated transportGO:0060627810.011
aromatic compound catabolic processGO:00194391680.011
regulation of actin filament based processGO:0032970420.011
purine nucleoside monophosphate biosynthetic processGO:0009127200.011
regulation of cell morphogenesisGO:0022604770.011
regulation of synaptic plasticityGO:0048167700.011
cellular ion homeostasisGO:00068731840.011
purine containing compound catabolic processGO:00725231380.011
positive regulation of transferase activityGO:0051347810.011
regulation of protein kinase activityGO:00458591050.011
organelle fissionGO:0048285250.011
regulation of myeloid leukocyte differentiationGO:0002761120.010
positive regulation of cell proliferationGO:00082842490.010
striated muscle cell differentiationGO:0051146390.010
synaptic transmissionGO:00072682350.010
angiogenesisGO:0001525530.010
macroautophagyGO:001623640.010
purine nucleoside monophosphate metabolic processGO:0009126840.010
regulation of intracellular signal transductionGO:19025312180.010
neuron deathGO:00709971270.010
positive regulation of purine nucleotide metabolic processGO:1900544910.010
positive regulation of rna metabolic processGO:00512542030.010
cellular response to extracellular stimulusGO:0031668730.010
cation transmembrane transportGO:00986552630.010
cardiac cell developmentGO:0055006160.010
hemopoiesisGO:0030097340.010
carboxylic acid transportGO:00469421150.010
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243430.010
single organism catabolic processGO:00447122830.010

Eif5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.053
nervous system diseaseDOID:86300.053
disease of cellular proliferationDOID:1456600.020
organ system cancerDOID:005068600.020
cancerDOID:16200.020