Rattus norvegicus

0 known processes

Six4

SIX homeobox 4

Six4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to estrogenGO:00436272320.053
single organism biosynthetic processGO:00447113420.052
positive regulation of nitrogen compound metabolic processGO:00511733340.045
nucleic acid templated transcriptionGO:00976593790.045
regulation of rna biosynthetic processGO:20011413810.045
regulation of nucleic acid templated transcriptionGO:19035063800.044
transcription dna templatedGO:00063513770.044
regulation of rna metabolic processGO:00512523910.042
intracellular signal transductionGO:00355563140.038
rna metabolic processGO:00160704060.038
rna biosynthetic processGO:00327743800.037
transcription from rna polymerase ii promoterGO:00063662520.036
reproductive processGO:00224143720.034
Fly
organophosphate metabolic processGO:00196373700.034
regulation of transcription dna templatedGO:00063553740.034
regulation of phosphorus metabolic processGO:00511743490.034
cellular component assemblyGO:00226073600.033
regulation of transcription from rna polymerase ii promoterGO:00063572340.033
protein complex assemblyGO:00064612630.032
cellular response to stressGO:00335542690.032
negative regulation of metabolic processGO:00098923310.032
negative regulation of macromolecule metabolic processGO:00106052600.032
regulation of multicellular organismal developmentGO:20000263760.031
positive regulation of biosynthetic processGO:00098913190.031
negative regulation of transcription dna templatedGO:00458921160.029
cellular response to oxygen containing compoundGO:19017013860.029
response to estradiolGO:00323551640.029
negative regulation of cell deathGO:00605482290.029
response to nutrient levelsGO:00316673700.029
cellular component biogenesisGO:00440853680.028
catabolic processGO:00090563510.028
negative regulation of nitrogen compound metabolic processGO:00511721610.028
protein phosphorylationGO:00064683450.028
regulation of phosphate metabolic processGO:00192203490.027
macromolecular complex subunit organizationGO:00439333390.027
apoptotic processGO:00069153810.026
response to acid chemicalGO:00011012220.026
regulation of cell differentiationGO:00455953200.026
regulation of cellular protein metabolic processGO:00322682670.026
response to inorganic substanceGO:00100353770.026
carboxylic acid metabolic processGO:00197522890.025
negative regulation of cellular metabolic processGO:00313242810.025
response to corticosteroidGO:00319602350.025
positive regulation of rna metabolic processGO:00512542030.025
nucleotide metabolic processGO:00091172790.024
negative regulation of gene expressionGO:00106291990.024
head developmentGO:00603222470.024
positive regulation of nucleobase containing compound metabolic processGO:00459353190.024
cellular amine metabolic processGO:0044106380.024
organic acid metabolic processGO:00060822920.023
positive regulation of gene expressionGO:00106282440.023
macromolecular complex assemblyGO:00650032730.023
brain developmentGO:00074202470.023
regulation of programmed cell deathGO:00430673410.023
macromolecule localizationGO:00330362520.023
oxoacid metabolic processGO:00434362900.023
regulation of signal transductionGO:00099663180.023
cellular response to lipidGO:00713962010.023
cellular response to endogenous stimulusGO:00714953770.023
programmed cell deathGO:00125013920.023
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.023
negative regulation of biosynthetic processGO:00098901680.023
single organism reproductive processGO:00447022970.022
Fly
positive regulation of cellular biosynthetic processGO:00313282950.022
regulation of molecular functionGO:00650093980.022
positive regulation of phosphorus metabolic processGO:00105622620.022
response to extracellular stimulusGO:00099913800.022
response to oxygen levelsGO:00704822650.022
positive regulation of phosphate metabolic processGO:00459372620.022
nucleobase containing small molecule metabolic processGO:00550863160.022
positive regulation of multicellular organismal processGO:00512403870.022
regulation of protein metabolic processGO:00512462890.021
regulation of cell developmentGO:00602842630.021
multicellular organismal reproductive processGO:00486092330.021
cellular catabolic processGO:00442482950.021
regulation of phosphorylationGO:00423252480.020
carbohydrate derivative metabolic processGO:19011353460.020
negative regulation of rna biosynthetic processGO:19026791180.020
response to woundingGO:00096112540.020
protein complex subunit organizationGO:00718223020.020
negative regulation of cellular biosynthetic processGO:00313271610.020
agingGO:00075682410.020
protein complex biogenesisGO:00702712630.020
multicellular organism reproductionGO:00325042330.020
nucleoside phosphate metabolic processGO:00067532830.020
response to decreased oxygen levelsGO:00362932370.020
negative regulation of macromolecule biosynthetic processGO:00105581480.020
central nervous system developmentGO:00074173110.020
chemical homeostasisGO:00488782920.020
homeostatic processGO:00425923310.019
negative regulation of rna metabolic processGO:00512531230.019
response to oxidative stressGO:00069791860.019
regulation of catalytic activityGO:00507903040.019
positive regulation of macromolecule biosynthetic processGO:00105572470.019
cellular homeostasisGO:00197252520.019
regulation of cell proliferationGO:00421273590.019
carbohydrate metabolic processGO:00059751300.019
response to ketoneGO:19016541820.018
reproductionGO:00000032450.018
amine metabolic processGO:0009308380.018
organelle organizationGO:00069962660.018
negative regulation of nucleic acid templated transcriptionGO:19035071170.018
organic substance catabolic processGO:19015753160.018
ribose phosphate metabolic processGO:00196932350.018
regulation of cellular localizationGO:00603412630.018
organonitrogen compound biosynthetic processGO:19015661670.018
cell projection organizationGO:00300303020.018
Fly
cellular amino acid metabolic processGO:00065201070.018
multi organism reproductive processGO:00447032620.018
negative regulation of transportGO:00510511360.018
cellular response to nitrogen compoundGO:19016992100.018
regulation of apoptotic processGO:00429813350.018
regulation of cellular amino acid metabolic processGO:000652120.018
purine containing compound metabolic processGO:00725212530.017
neurological system processGO:00508772190.017
negative regulation of programmed cell deathGO:00430691830.017
cellular response to organonitrogen compoundGO:00714171970.017
protein localizationGO:00081041910.017
intracellular transportGO:00469071850.017
blood circulationGO:00080151830.017
neuron projection developmentGO:00311752730.017
Fly
regulation of anatomical structure sizeGO:00900661350.017
regulation of protein modification processGO:00313991940.017
positive regulation of molecular functionGO:00440932300.017
regulation of neurogenesisGO:00507672470.017
regulation of canonical wnt signaling pathwayGO:006082840.017
protein oligomerizationGO:00512591910.017
regulation of nervous system developmentGO:00519602640.017
positive regulation of transcription dna templatedGO:00458931970.017
regulation of cellular component organizationGO:00511283680.017
tissue developmentGO:00098882520.017
Fly
muscle system processGO:00030121150.017
neuron differentiationGO:00301823680.016
Fly
single organism organelle organizationGO:19025891800.016
organophosphate biosynthetic processGO:00904071430.016
positive regulation of apoptotic processGO:00430651540.016
positive regulation of phosphorylationGO:00423271770.016
small gtpase mediated signal transductionGO:0007264360.016
positive regulation of cell proliferationGO:00082842490.016
regulation of system processGO:00440572080.016
positive regulation of rna biosynthetic processGO:19026801970.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
regulation of cell cycleGO:0051726730.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
metal ion homeostasisGO:00550651860.016
regulation of protein phosphorylationGO:00019321830.015
purine nucleotide metabolic processGO:00061632290.015
anterior posterior pattern specificationGO:000995210.015
positive regulation of cell communicationGO:00106472710.015
regulation of proteasomal protein catabolic processGO:006113640.015
secretionGO:00469033070.015
cellular response to organic cyclic compoundGO:00714072020.015
ribonucleotide metabolic processGO:00092592310.015
calcium ion homeostasisGO:00550741620.015
response to peptide hormoneGO:00434342780.015
cellular response to hormone stimulusGO:00328702470.015
positive regulation of protein metabolic processGO:00512471780.014
negative regulation of apoptotic processGO:00430661810.014
cellular ion homeostasisGO:00068731840.014
reproductive structure developmentGO:00486081280.014
Fly
response to hypoxiaGO:00016662310.014
purine ribonucleotide metabolic processGO:00091502270.014
cation homeostasisGO:00550801950.014
female pregnancyGO:00075651220.014
ion homeostasisGO:00508012120.014
regulation of cellular amine metabolic processGO:003323880.014
axis specificationGO:000979840.014
response to nutrientGO:00075842480.014
circulatory system processGO:00030131830.014
cation transportGO:00068123820.014
cellular response to growth factor stimulusGO:00713631620.014
developmental process involved in reproductionGO:00030061590.014
Fly
anatomical structure morphogenesisGO:00096532980.014
Fly
circadian rhythmGO:0007623880.014
positive regulation of cell differentiationGO:00455972170.014
response to peptideGO:19016522920.014
cell cell signalingGO:00072673350.014
cytosolic calcium ion homeostasisGO:00514801400.014
regulation of neuron differentiationGO:00456642080.014
negative regulation of mitotic cell cycle phase transitionGO:190199130.014
cell cycleGO:00070491010.014
proteolysisGO:00065081750.014
cellular nitrogen compound catabolic processGO:00442701630.013
positive regulation of catalytic activityGO:00430851840.013
positive regulation of signalingGO:00230562700.013
response to biotic stimulusGO:00096072260.013
heterocycle catabolic processGO:00467001670.013
single organism catabolic processGO:00447122830.013
regulation of intracellular signal transductionGO:19025312180.013
nucleoside phosphate biosynthetic processGO:19012931020.013
single organism intracellular transportGO:19025821660.013
response to monosaccharideGO:00342841590.013
ras protein signal transductionGO:0007265290.013
positive regulation of transportGO:00510502450.013
regenerationGO:00310991630.013
cellular calcium ion homeostasisGO:00068741600.013
cytoplasmic transportGO:00164821150.013
positive regulation of cellular component organizationGO:00511302000.013
negative regulation of cell cycle phase transitionGO:190198840.013
cell cycle checkpointGO:000007520.013
positive regulation of cellular amine metabolic processGO:003324030.013
regulation of nucleotide metabolic processGO:00061401170.013
positive regulation of developmental processGO:00510942830.013
cellular protein localizationGO:00346131220.013
cellular response to peptideGO:19016531330.013
regulation of cellular catabolic processGO:00313291010.013
small molecule biosynthetic processGO:00442831240.012
positive regulation of cell deathGO:00109421840.012
cellular cation homeostasisGO:00300031800.012
response to external biotic stimulusGO:00432072210.012
defense responseGO:00069521940.012
divalent inorganic cation homeostasisGO:00725071650.012
cellular carbohydrate metabolic processGO:0044262720.012
response to glucocorticoidGO:00513842230.012
response to metal ionGO:00100382530.012
multi multicellular organism processGO:00447061380.012
regulation of cell projection organizationGO:00313441750.012
oxidation reduction processGO:00551143040.012
cellular macromolecule localizationGO:00707271220.012
cellular response to acid chemicalGO:0071229750.012
regulation of membrane potentialGO:00423911100.012
vascular process in circulatory systemGO:0003018960.012
action potentialGO:0001508540.012
secretion by cellGO:00329402480.012
regulation of cellular ketone metabolic processGO:0010565270.012
single organism carbohydrate metabolic processGO:00447231180.012
response to reactive oxygen speciesGO:00003021200.012
rhythmic processGO:00485111560.012
response to carbohydrateGO:00097431830.012
cellular metal ion homeostasisGO:00068751720.012
nucleotide biosynthetic processGO:0009165980.012
non canonical wnt signaling pathwayGO:003556730.012
cellular ketone metabolic processGO:0042180510.012
regulation of protein kinase activityGO:00458591050.012
cell part morphogenesisGO:00329901230.012
Fly
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.012
response to temperature stimulusGO:0009266940.012
response to growth factorGO:00708481890.012
cell type specific apoptotic processGO:00972851340.011
response to other organismGO:00517072200.011
positive regulation of response to stimulusGO:00485842850.011
negative regulation of multicellular organismal processGO:00512412030.011
response to bacteriumGO:00096172000.011
neuron deathGO:00709971270.011
carbohydrate derivative biosynthetic processGO:19011371240.011
nucleobase containing compound catabolic processGO:00346551520.011
cellular lipid metabolic processGO:00442552080.011
positive regulation of cellular protein metabolic processGO:00322701670.011
regulation of hormone levelsGO:00108171870.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
sexual reproductionGO:00199531480.011
regulation of blood vessel sizeGO:0050880890.011
salivary gland developmentGO:000743130.011
lipid metabolic processGO:00066292830.011
gland developmentGO:00487321550.011
cellular chemical homeostasisGO:00550822470.011
protein transportGO:00150311320.011
regulation of secretion by cellGO:19035302080.011
embryonic skeletal system developmentGO:004870630.011
positive regulation of nervous system developmentGO:00519621780.011
regulation of secretionGO:00510462240.011
neuron projection morphogenesisGO:00488121220.011
Fly
regulation of transferase activityGO:00513381230.011
response to hexoseGO:00097461440.011
synaptic transmissionGO:00072682350.011
organ regenerationGO:00311001010.010
positive regulation of cytosolic calcium ion concentrationGO:00072041220.010
regulation of tube sizeGO:0035150890.010
regulation of catabolic processGO:00098941130.010
response to cytokineGO:00340972150.010
response to glucoseGO:00097491360.010
aromatic compound catabolic processGO:00194391680.010
regulation of organelle organizationGO:0033043800.010
gastrulationGO:000736920.010
spermatogenesisGO:0007283990.010
positive regulation of signal transductionGO:00099671750.010
positive regulation of protein modification processGO:00314011420.010
maintenance of locationGO:0051235170.010
transmembrane transportGO:00550854120.010
lipid storageGO:001991510.010
regulation of cellular component biogenesisGO:0044087860.010
vesicle mediated transportGO:00161921810.010
organonitrogen compound catabolic processGO:19015651790.010
regulation of mapk cascadeGO:00434081160.010

Six4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.024
disease of anatomical entityDOID:700.024
sensory system diseaseDOID:005015500.017
myopathyDOID:42300.017
musculoskeletal system diseaseDOID:1700.017
muscular diseaseDOID:008000000.017
muscle tissue diseaseDOID:6600.017
disease of metabolismDOID:001466700.011
eye and adnexa diseaseDOID:149200.010
eye diseaseDOID:561400.010