Rattus norvegicus

64 known processes

Six3

SIX homeobox 3

Six3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of secretion by cellGO:19035302080.134
ion transmembrane transportGO:00342203650.104
positive regulation of nitrogen compound metabolic processGO:00511733340.101
rna biosynthetic processGO:00327743800.101
macromolecule localizationGO:00330362520.100
positive regulation of rna biosynthetic processGO:19026801970.095
rna metabolic processGO:00160704060.092
metal ion transportGO:00300012890.091
positive regulation of nucleic acid templated transcriptionGO:19035081970.089
regulation of transcription from rna polymerase ii promoterGO:00063572340.088
secretion by cellGO:00329402480.086
inorganic ion transmembrane transportGO:00986602290.082
response to external biotic stimulusGO:00432072210.075
response to metal ionGO:00100382530.074
regulation of cellular localizationGO:00603412630.070
lymphoid progenitor cell differentiationGO:000232020.069
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.069
transmembrane transportGO:00550854120.069
cell cell signalingGO:00072673350.068
regulation of transcription dna templatedGO:00063553740.067
response to molecule of bacterial originGO:00022371940.067
brain developmentGO:00074202470.065
negative regulation of cellular metabolic processGO:00313242810.064
response to bacteriumGO:00096172000.063
negative regulation of cellular biosynthetic processGO:00313271610.062
neuron differentiationGO:00301823680.062
positive regulation of secretion by cellGO:19035321280.061
cellular response to hormone stimulusGO:00328702470.061
regulation of rna metabolic processGO:00512523910.060
negative regulation of macromolecule biosynthetic processGO:00105581480.059
response to glucocorticoidGO:00513842230.059
negative regulation of nucleic acid templated transcriptionGO:19035071170.058
inorganic cation transmembrane transportGO:00986622020.057
central nervous system developmentGO:00074173110.057
nucleic acid templated transcriptionGO:00976593790.056
regulation of neurogenesisGO:00507672470.056
regenerationGO:00310991630.056
negative regulation of multicellular organismal processGO:00512412030.054
calcium ion transportGO:00068161310.054
divalent metal ion transportGO:00708381320.053
negative regulation of growthGO:0045926370.051
transcription from rna polymerase ii promoterGO:00063662520.050
organ formationGO:004864530.048
regulation of rna biosynthetic processGO:20011413810.048
regulation of nucleic acid templated transcriptionGO:19035063800.047
negative regulation of nitrogen compound metabolic processGO:00511721610.047
negative regulation of metabolic processGO:00098923310.047
cardiac ventricle developmentGO:000323110.046
negative regulation of gene expressionGO:00106291990.045
regulation of transporter activityGO:0032409500.044
development of primary sexual characteristicsGO:00451371070.043
response to lipopolysaccharideGO:00324961910.043
negative regulation of cellular component organizationGO:0051129830.041
positive regulation of secretionGO:00510471400.040
neuromuscular processGO:005090520.040
carbohydrate derivative metabolic processGO:19011353460.037
regulation of sodium ion transmembrane transporter activityGO:200064940.037
heart morphogenesisGO:000300730.036
response to inorganic substanceGO:00100353770.036
inflammatory responseGO:00069541500.036
response to corticosteroidGO:00319602350.036
secretionGO:00469033070.036
insulin secretionGO:0030073690.036
regulation of growthGO:00400081050.036
response to cytokineGO:00340972150.036
negative regulation of macromolecule metabolic processGO:00106052600.035
regulation of transmembrane transporter activityGO:0022898490.035
cellular ketone metabolic processGO:0042180510.034
regulation of cellular component organizationGO:00511283680.034
cation transmembrane transportGO:00986552630.034
negative regulation of nucleobase containing compound metabolic processGO:00459341530.034
positive regulation of macromolecule biosynthetic processGO:00105572470.033
head developmentGO:00603222470.033
divalent inorganic cation transportGO:00725111340.033
homeostatic processGO:00425923310.033
regulation of hormone secretionGO:00468831060.032
positive regulation of gene expressionGO:00106282440.032
negative regulation of rna metabolic processGO:00512531230.032
positive regulation of nucleobase containing compound metabolic processGO:00459353190.032
nucleobase containing small molecule metabolic processGO:00550863160.032
intracellular signal transductionGO:00355563140.032
calcium ion transmembrane transportGO:0070588700.031
transcription dna templatedGO:00063513770.030
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.030
regulation of secretionGO:00510462240.030
negative regulation of biosynthetic processGO:00098901680.029
regulation of nervous system developmentGO:00519602640.029
regulation of multicellular organismal developmentGO:20000263760.029
cellular response to oxygen containing compoundGO:19017013860.029
positive regulation of phosphate metabolic processGO:00459372620.029
metanephric s shaped body morphogenesisGO:007228420.029
regulation of ion transmembrane transporter activityGO:0032412480.028
programmed cell deathGO:00125013920.028
protein localizationGO:00081041910.028
forebrain developmentGO:0030900980.028
signal releaseGO:00230611450.028
positive regulation of biosynthetic processGO:00098913190.028
neuron fate commitmentGO:004866340.028
vesicle mediated transportGO:00161921810.028
negative regulation of transcription dna templatedGO:00458921160.028
sodium ion transportGO:0006814820.027
metanephric comma shaped body morphogenesisGO:007227820.027
regulation of phosphate metabolic processGO:00192203490.027
response to acid chemicalGO:00011012220.027
regulation of ion transmembrane transportGO:00347651210.026
regulation of purine nucleotide metabolic processGO:19005421150.026
cell projection organizationGO:00300303020.026
anatomical structure morphogenesisGO:00096532980.026
positive regulation of cellular biosynthetic processGO:00313282950.025
cellular ion homeostasisGO:00068731840.025
regulation of phosphorus metabolic processGO:00511743490.025
cellular homeostasisGO:00197252520.025
cellular macromolecule localizationGO:00707271220.025
glutamate receptor signaling pathwayGO:0007215430.024
hormone secretionGO:00468791150.024
growthGO:00400071650.024
regulation of molecular functionGO:00650093980.024
regulation of hormone levelsGO:00108171870.024
positive regulation of transportGO:00510502450.024
peptide secretionGO:0002790860.024
response to biotic stimulusGO:00096072260.024
cardiac chamber developmentGO:000320510.024
developmental growthGO:00485891000.023
regulation of transmembrane transportGO:00347621220.023
cellular protein localizationGO:00346131220.022
apoptotic processGO:00069153810.022
protein complex subunit organizationGO:00718223020.022
positive regulation of rna metabolic processGO:00512542030.022
negative regulation of cell deathGO:00605482290.022
agingGO:00075682410.022
heart developmentGO:0007507720.022
regulation of cell differentiationGO:00455953200.021
positive regulation of cell differentiationGO:00455972170.021
pro t cell differentiationGO:000257210.021
specification of organ identityGO:001009220.021
cell fate determinationGO:000170920.021
cellular response to stressGO:00335542690.020
tissue developmentGO:00098882520.020
positive regulation of response to stimulusGO:00485842850.020
cellular component morphogenesisGO:00329891550.020
purine ribonucleotide metabolic processGO:00091502270.020
wound healingGO:00420601220.020
response to other organismGO:00517072200.020
purine containing compound metabolic processGO:00725212530.020
eye morphogenesisGO:004859240.019
retinal ganglion cell axon guidanceGO:003129010.019
organic acid metabolic processGO:00060822920.019
positive regulation of multicellular organismal processGO:00512403870.019
establishment of protein localizationGO:00451841410.019
response to woundingGO:00096112540.019
regulation of calcium ion transportGO:0051924770.019
monosaccharide metabolic processGO:0005996610.019
positive regulation of signalingGO:00230562700.019
spinal cord developmentGO:0021510270.019
ribose phosphate metabolic processGO:00196932350.019
organonitrogen compound biosynthetic processGO:19015661670.018
carboxylic acid metabolic processGO:00197522890.018
organophosphate metabolic processGO:00196373700.018
establishment of synaptic vesicle localizationGO:0097480230.018
response to extracellular stimulusGO:00099913800.018
nucleotide metabolic processGO:00091172790.018
regulation of lipid metabolic processGO:0019216680.018
regulation of metal ion transportGO:00109591180.018
developmental process involved in reproductionGO:00030061590.018
regulation of vesicle mediated transportGO:0060627810.018
anatomical structure formation involved in morphogenesisGO:0048646830.018
muscle system processGO:00030121150.018
purine nucleotide biosynthetic processGO:0006164830.018
regulation of apoptotic processGO:00429813350.018
positive regulation of cytosolic calcium ion concentrationGO:00072041220.018
gland developmentGO:00487321550.018
cellular response to corticosteroid stimulusGO:0071384690.017
negative regulation of cell communicationGO:00106481580.017
cellular divalent inorganic cation homeostasisGO:00725031620.017
nucleoside phosphate metabolic processGO:00067532830.017
endocrine system developmentGO:0035270300.017
cell morphogenesisGO:00009021420.017
developmental inductionGO:003112820.017
s shaped body morphogenesisGO:007205020.017
axis specificationGO:000979840.017
cellular amino acid metabolic processGO:00065201070.017
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.017
response to nutrient levelsGO:00316673700.017
multicellular organismal reproductive processGO:00486092330.017
ion homeostasisGO:00508012120.017
sodium ion transmembrane transportGO:0035725670.017
regulation of cell morphogenesisGO:0022604770.016
purine nucleoside metabolic processGO:00422781690.016
cellular response to glucocorticoid stimulusGO:0071385680.016
chemical homeostasisGO:00488782920.016
regulation of ion transportGO:00432692450.016
positive regulation of cellular component organizationGO:00511302000.016
regulation of signal transductionGO:00099663180.016
cellular amine metabolic processGO:0044106380.016
response to glucoseGO:00097491360.016
single organism intracellular transportGO:19025821660.016
negative regulation of apoptotic processGO:00430661810.016
regulation of establishment of protein localizationGO:0070201690.016
gliogenesisGO:0042063930.016
macromolecular complex assemblyGO:00650032730.016
single organism membrane organizationGO:0044802740.016
salivary gland morphogenesisGO:000743510.016
response to ketoneGO:19016541820.016
single organism reproductive processGO:00447022970.016
reproductive structure developmentGO:00486081280.016
oxidation reduction processGO:00551143040.016
nucleoside metabolic processGO:00091161790.016
mesoderm developmentGO:000749820.016
cellular metal ion homeostasisGO:00068751720.016
cell morphogenesis involved in differentiationGO:00009041190.015
regulation of phosphatidylinositol dephosphorylationGO:006030410.015
response to peptide hormoneGO:00434342780.015
negative regulation of molecular functionGO:00440921330.015
negative regulation of signal transductionGO:0009968830.015
regulation of cellular ketone metabolic processGO:0010565270.015
sex differentiationGO:00075481130.015
reproductive processGO:00224143720.015
negative regulation of rna biosynthetic processGO:19026791180.015
carbohydrate metabolic processGO:00059751300.015
female sex differentiationGO:0046660590.015
peptide hormone secretionGO:0030072840.015
organ regenerationGO:00311001010.015
response to vitaminGO:00332731310.015
negative regulation of transportGO:00510511360.015
regulation of organ formationGO:000315620.015
response to hexoseGO:00097461440.015
regulation of reactive oxygen species biosynthetic processGO:190342650.015
neuron projection guidanceGO:0097485240.015
cellular chemical homeostasisGO:00550822470.015
ribonucleoside metabolic processGO:00091191740.015
single organism carbohydrate metabolic processGO:00447231180.015
purine nucleoside triphosphate metabolic processGO:00091441410.015
neuron projection developmentGO:00311752730.014
carbohydrate derivative catabolic processGO:19011361470.014
response to radiationGO:00093141370.014
nitrogen compound transportGO:00717052290.014
regulation of neuron differentiationGO:00456642080.014
regulation of cell cycleGO:0051726730.014
cation homeostasisGO:00550801950.014
female gonad developmentGO:0008585530.014
positive regulation of developmental processGO:00510942830.014
axon guidanceGO:0007411240.014
organic cyclic compound catabolic processGO:19013611750.014
cell growthGO:00160491040.014
intracellular transportGO:00469071850.014
ribonucleotide metabolic processGO:00092592310.013
regulation of mapk cascadeGO:00434081160.013
sensory perception of light stimulusGO:005095330.013
retina morphogenesis in camera type eyeGO:006004210.013
single organism cellular localizationGO:19025801020.013
protein complex biogenesisGO:00702712630.013
positive regulation of cell developmentGO:00107201760.013
cation transportGO:00068123820.013
positive regulation of cell proliferationGO:00082842490.013
positive regulation of nucleotide metabolic processGO:0045981910.013
regulation of cellular amino acid metabolic processGO:000652120.013
proteolysisGO:00065081750.013
cellular response to growth factor stimulusGO:00713631620.013
positive regulation of cell deathGO:00109421840.013
tube developmentGO:0035295890.013
amide transportGO:00428861050.013
regulation of cell growthGO:0001558850.013
regulation of neuron projection developmentGO:00109751610.013
inner ear morphogenesisGO:004247210.013
visual perceptionGO:000760130.012
regulation of membrane potentialGO:00423911100.012
positive regulation of molecular functionGO:00440932300.012
lipid metabolic processGO:00066292830.012
b cell differentiationGO:003018320.012
cell cell signaling involved in cell fate commitmentGO:004516820.012
response to growth factorGO:00708481890.012
neuronal action potentialGO:0019228350.012
cellular response to lipidGO:00713962010.012
single organism biosynthetic processGO:00447113420.012
synaptic vesicle localizationGO:0097479240.012
heterocycle catabolic processGO:00467001670.012
endocytosisGO:0006897840.012
synaptic vesicle endocytosisGO:004848840.012
oxoacid metabolic processGO:00434362900.012
cytoplasmic transportGO:00164821150.012
hormone transportGO:00099141210.012
tissue regenerationGO:0042246360.012
positive regulation of hormone secretionGO:0046887650.012
regulation of homeostatic processGO:00328441010.012
protein complex assemblyGO:00064612630.012
positive regulation of insulin secretionGO:0032024360.012
regulation of sodium ion transportGO:0002028210.012
nucleoside triphosphate metabolic processGO:00091411440.012
regulation of programmed cell deathGO:00430673410.012
regulation of cell morphogenesis involved in differentiationGO:0010769720.012
cellular response to organic cyclic compoundGO:00714072020.011
regulation of protein transportGO:0051223680.011
regulation of erk1 and erk2 cascadeGO:0070372410.011
cellular response to organonitrogen compoundGO:00714171970.011
positive regulation of phosphorylationGO:00423271770.011
neurotransmitter secretionGO:0007269330.011
development of primary female sexual characteristicsGO:0046545560.011
signal transduction by phosphorylationGO:00230141440.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
monovalent inorganic cation transportGO:00156721720.011
response to peptideGO:19016522920.011
membrane organizationGO:0061024940.011
gonad developmentGO:00084061040.011
response to nutrientGO:00075842480.011
aromatic compound catabolic processGO:00194391680.011
regulation of phosphorylationGO:00423252480.011
regulation of peptide secretionGO:0002791820.011
glycosyl compound metabolic processGO:19016571820.011
carbohydrate derivative biosynthetic processGO:19011371240.011
neuron developmentGO:00486662860.011
regulation of protein localizationGO:0032880810.011
response to carbohydrateGO:00097431830.011
response to decreased oxygen levelsGO:00362932370.011
olfactory behaviorGO:004204820.011
regulation of insulin secretionGO:0050796650.011
cell differentiation involved in kidney developmentGO:006100540.011
organelle localizationGO:0051640550.011
sensory organ developmentGO:0007423740.011
dorsal ventral axon guidanceGO:003356310.011
motor neuron axon guidanceGO:000804510.011
glial cell differentiationGO:0010001650.011
regulation of system processGO:00440572080.011
amine metabolic processGO:0009308380.011
protein transportGO:00150311320.011
macromolecular complex subunit organizationGO:00439333390.011
hexose metabolic processGO:0019318580.011
regulation of anatomical structure morphogenesisGO:00226031410.011
male gamete generationGO:0048232990.011
glucose metabolic processGO:0006006520.010
sequestering of metal ionGO:005123890.010
positive regulation of transcription dna templatedGO:00458931970.010
telencephalon developmentGO:0021537620.010
nucleoside phosphate catabolic processGO:19012921400.010
positive regulation of purine nucleotide metabolic processGO:1900544910.010
regulation of catabolic processGO:00098941130.010
regulation of protein metabolic processGO:00512462890.010
regulation of cell projection organizationGO:00313441750.010
ribonucleoside catabolic processGO:00424541260.010
epithelium developmentGO:0060429960.010
negative regulation of epithelial cell proliferationGO:0050680160.010
reactive oxygen species biosynthetic processGO:190340980.010
ras protein signal transductionGO:0007265290.010
organelle organizationGO:00069962660.010

Six3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
musculoskeletal system diseaseDOID:1700.035
nervous system diseaseDOID:86300.031
sensory system diseaseDOID:005015500.026
connective tissue diseaseDOID:6500.017
bone diseaseDOID:008000100.015
eye diseaseDOID:561400.014
eye and adnexa diseaseDOID:149200.014
myopathyDOID:42300.011
muscle tissue diseaseDOID:6600.011
muscular diseaseDOID:008000000.011
endocrine system diseaseDOID:2800.011