Rattus norvegicus

134 known processes

Hhex

hematopoietically expressed homeobox

(Aliases: Hex)

Hhex biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
intracellular signal transductionGO:00355563140.159
positive regulation of response to stimulusGO:00485842850.136
regulation of intracellular signal transductionGO:19025312180.120
positive regulation of nitrogen compound metabolic processGO:00511733340.100
Human
regulation of nucleic acid templated transcriptionGO:19035063800.100
regulation of signal transductionGO:00099663180.096
nucleic acid templated transcriptionGO:00976593790.093
positive regulation of signal transductionGO:00099671750.087
rna metabolic processGO:00160704060.087
wound healingGO:00420601220.082
immune system processGO:00023762040.080
regulation of molecular functionGO:00650093980.079
Human
programmed cell deathGO:00125013920.076
response to woundingGO:00096112540.070
rna biosynthetic processGO:00327743800.070
regulation of phosphate metabolic processGO:00192203490.069
Human
central nervous system developmentGO:00074173110.068
regulation of programmed cell deathGO:00430673410.067
response to peptideGO:19016522920.067
apoptotic processGO:00069153810.066
cellular chemical homeostasisGO:00550822470.066
cardiovascular system developmentGO:00723581340.066
regulation of neuron deathGO:19012141150.066
regulation of immune system processGO:00026821230.065
positive regulation of nucleobase containing compound metabolic processGO:00459353190.065
Human
regulation of rna biosynthetic processGO:20011413810.057
homeostatic processGO:00425923310.057
anatomical structure morphogenesisGO:00096532980.056
positive regulation of macromolecule biosynthetic processGO:00105572470.055
Human
positive regulation of cellular biosynthetic processGO:00313282950.055
Human
regulation of rna metabolic processGO:00512523910.055
regulation of transcription from rna polymerase ii promoterGO:00063572340.054
regulation of apoptotic processGO:00429813350.054
positive regulation of rna metabolic processGO:00512542030.054
Human
neuron deathGO:00709971270.053
anterior posterior pattern specificationGO:000995210.052
cellular amine metabolic processGO:0044106380.051
protein phosphorylationGO:00064683450.050
Human
cell migrationGO:00164771970.050
positive regulation of cell differentiationGO:00455972170.049
response to hypoxiaGO:00016662310.049
cellular amino acid metabolic processGO:00065201070.048
positive regulation of cell communicationGO:00106472710.048
regulation of cellular amino acid metabolic processGO:000652120.047
cellular response to oxygen containing compoundGO:19017013860.047
cellular homeostasisGO:00197252520.047
positive regulation of rna biosynthetic processGO:19026801970.046
Human
positive regulation of signalingGO:00230562700.046
transcription dna templatedGO:00063513770.045
regulation of cellular ketone metabolic processGO:0010565270.045
regulation of multicellular organismal developmentGO:20000263760.044
negative regulation of cell communicationGO:00106481580.044
negative regulation of nitrogen compound metabolic processGO:00511721610.043
tissue developmentGO:00098882520.043
regulation of cellular component organizationGO:00511283680.043
positive regulation of catalytic activityGO:00430851840.042
cellular component biogenesisGO:00440853680.042
negative regulation of cellular metabolic processGO:00313242810.042
regulation of hydrolase activityGO:00513361430.041
negative regulation of metabolic processGO:00098923310.041
response to acid chemicalGO:00011012220.040
response to oxygen levelsGO:00704822650.039
regulation of cellular protein metabolic processGO:00322682670.039
Human
regulation of catalytic activityGO:00507903040.039
Human
regulation of transcription dna templatedGO:00063553740.039
amine metabolic processGO:0009308380.038
regulation of kinase activityGO:00435491170.038
Human
cellular ketone metabolic processGO:0042180510.038
regulation of cellular amine metabolic processGO:003323880.038
positive regulation of cell proliferationGO:00082842490.037
regulation of phosphorus metabolic processGO:00511743490.037
Human
organophosphate metabolic processGO:00196373700.037
regulation of cell differentiationGO:00455953200.037
positive regulation of developmental processGO:00510942830.037
cation transportGO:00068123820.036
negative regulation of response to stimulusGO:00485851550.036
regulation of phosphorylationGO:00423252480.035
Human
behaviorGO:00076102050.035
oxoacid metabolic processGO:00434362900.034
transcription from rna polymerase ii promoterGO:00063662520.034
enzyme linked receptor protein signaling pathwayGO:00071671160.034
nitrogen compound transportGO:00717052290.034
Human
cellular response to stressGO:00335542690.034
brain developmentGO:00074202470.034
response to nutrient levelsGO:00316673700.034
response to decreased oxygen levelsGO:00362932370.034
single organism reproductive processGO:00447022970.033
mesoderm developmentGO:000749820.033
defense responseGO:00069521940.032
positive regulation of neurogenesisGO:00507691650.032
nucleobase containing small molecule metabolic processGO:00550863160.032
regulation of cell projection organizationGO:00313441750.032
regulation of neurogenesisGO:00507672470.032
negative regulation of macromolecule metabolic processGO:00106052600.032
positive regulation of immune responseGO:0050778420.032
positive regulation of intracellular signal transductionGO:19025331380.031
cellular response to organonitrogen compoundGO:00714171970.031
regulation of protein metabolic processGO:00512462890.031
Human
inflammatory responseGO:00069541500.031
organic acid metabolic processGO:00060822920.030
axis specificationGO:000979840.030
anatomical structure formation involved in morphogenesisGO:0048646830.030
purine containing compound metabolic processGO:00725212530.030
response to peptide hormoneGO:00434342780.030
positive regulation of gene expressionGO:00106282440.029
Human
carboxylic acid metabolic processGO:00197522890.029
neuron developmentGO:00486662860.029
circulatory system developmentGO:00723591340.029
single organism biosynthetic processGO:00447113420.028
carbohydrate derivative metabolic processGO:19011353460.028
cellular response to hormone stimulusGO:00328702470.028
positive regulation of cell developmentGO:00107201760.028
negative regulation of programmed cell deathGO:00430691830.028
cellular component assemblyGO:00226073600.028
head developmentGO:00603222470.028
cell activationGO:0001775970.028
macromolecular complex assemblyGO:00650032730.028
negative regulation of cell deathGO:00605482290.027
positive regulation of protein metabolic processGO:00512471780.027
nucleoside phosphate metabolic processGO:00067532830.027
positive regulation of nucleic acid templated transcriptionGO:19035081970.027
Human
positive regulation of phosphorylationGO:00423271770.027
chemical homeostasisGO:00488782920.027
calcium ion homeostasisGO:00550741620.027
positive regulation of molecular functionGO:00440932300.027
cellular component movementGO:00069282480.027
positive regulation of transportGO:00510502450.027
multicellular organism reproductionGO:00325042330.027
regulation of cellular catabolic processGO:00313291010.027
response to extracellular stimulusGO:00099913800.026
positive regulation of cell motilityGO:2000147970.026
cellular component morphogenesisGO:00329891550.026
regulation of cell developmentGO:00602842630.026
regulation of nervous system developmentGO:00519602640.026
mapk cascadeGO:00001651400.026
cell motilityGO:00488702020.026
cellular calcium ion homeostasisGO:00068741600.026
neurological system processGO:00508772190.026
cellular ion homeostasisGO:00068731840.026
stress activated protein kinase signaling cascadeGO:0031098370.025
localization of cellGO:00516742020.025
positive regulation of cellular component organizationGO:00511302000.025
ribose phosphate metabolic processGO:00196932350.025
cell type specific apoptotic processGO:00972851340.025
ribonucleotide metabolic processGO:00092592310.025
positive regulation of immune system processGO:0002684900.025
neuron differentiationGO:00301823680.025
locomotionGO:00400112370.025
sensory perceptionGO:00076001010.025
positive regulation of phosphate metabolic processGO:00459372620.025
negative regulation of cellular biosynthetic processGO:00313271610.024
regulation of membrane potentialGO:00423911100.024
positive regulation of multicellular organismal processGO:00512403870.024
positive regulation of cellular amino acid metabolic processGO:004576410.024
negative regulation of apoptotic processGO:00430661810.024
circadian rhythmGO:0007623880.024
cell projection organizationGO:00300303020.024
tube developmentGO:0035295890.024
catabolic processGO:00090563510.024
glycosyl compound metabolic processGO:19016571820.024
peptidyl amino acid modificationGO:00181931260.024
response to ethanolGO:00454711620.024
negative regulation of signalingGO:00230571570.024
regulation of locomotionGO:00400121480.023
neuron projection developmentGO:00311752730.023
response to monosaccharideGO:00342841590.023
cell adhesionGO:00071551100.023
regulation of cellular component movementGO:00512701500.023
positive regulation of biosynthetic processGO:00098913190.023
Human
positive regulation of nervous system developmentGO:00519621780.023
leukocyte activationGO:0045321760.023
response to glucocorticoidGO:00513842230.023
regulation of neuron differentiationGO:00456642080.023
regulation of cell proliferationGO:00421273590.022
response to inorganic substanceGO:00100353770.022
biological adhesionGO:00226101100.022
multicellular organismal reproductive processGO:00486092330.022
positive regulation of phosphorus metabolic processGO:00105622620.022
gtp catabolic processGO:0006184710.021
reproductive processGO:00224143720.021
organic substance catabolic processGO:19015753160.021
positive regulation of protein phosphorylationGO:00019341350.021
cellular metal ion homeostasisGO:00068751720.021
response to carbohydrateGO:00097431830.021
cellular response to organic cyclic compoundGO:00714072020.021
cellular response to endogenous stimulusGO:00714953770.021
purine nucleotide catabolic processGO:00061951360.021
regulation of cell migrationGO:00303341280.021
divalent inorganic cation homeostasisGO:00725071650.021
response to lipopolysaccharideGO:00324961910.021
response to nutrientGO:00075842480.021
response to estrogenGO:00436272320.021
cellular response to lipidGO:00713962010.021
regulation of response to stressGO:00801341260.020
response to growth factorGO:00708481890.020
positive regulation of cell projection organizationGO:00313461110.020
cytokine productionGO:0001816610.020
cellular divalent inorganic cation homeostasisGO:00725031620.020
developmental process involved in reproductionGO:00030061590.020
aromatic compound catabolic processGO:00194391680.020
metal ion transportGO:00300012890.020
cellular cation homeostasisGO:00300031800.020
macromolecular complex subunit organizationGO:00439333390.020
regulation of nucleotide metabolic processGO:00061401170.020
positive regulation of apoptotic processGO:00430651540.020
negative regulation of rna biosynthetic processGO:19026791180.020
divalent metal ion transportGO:00708381320.020
purine nucleotide metabolic processGO:00061632290.019
purine ribonucleotide metabolic processGO:00091502270.019
positive regulation of neuron differentiationGO:00456661260.019
insulin like growth factor receptor signaling pathwayGO:004800930.019
intracellular transportGO:00469071850.019
Human
regulation of cell cycleGO:0051726730.019
Human
negative regulation of immune system processGO:0002683390.019
positive regulation of cellular protein metabolic processGO:00322701670.019
multi organism reproductive processGO:00447032620.019
regulation of canonical wnt signaling pathwayGO:006082840.019
blood vessel morphogenesisGO:0048514580.019
regenerationGO:00310991630.018
signal transduction by phosphorylationGO:00230141440.018
response to radiationGO:00093141370.018
positive regulation of protein modification processGO:00314011420.018
reproductionGO:00000032450.018
regulation of mapk cascadeGO:00434081160.018
regulation of neuron projection developmentGO:00109751610.018
response to glucoseGO:00097491360.018
neuronal action potentialGO:0019228350.018
cellular macromolecule localizationGO:00707271220.018
Human
positive regulation of gtpase activityGO:0043547470.018
nucleotide metabolic processGO:00091172790.018
b cell differentiationGO:003018320.018
positive regulation of cell deathGO:00109421840.018
positive regulation of cellular amine metabolic processGO:003324030.017
embryonic pattern specificationGO:000988010.017
angiogenesisGO:0001525530.017
response to biotic stimulusGO:00096072260.017
positive regulation of neuron projection developmentGO:0010976990.017
cell cell signalingGO:00072673350.017
response to ketoneGO:19016541820.017
gland developmentGO:00487321550.017
cellular response to alcoholGO:0097306870.017
calcium ion transportGO:00068161310.017
ras protein signal transductionGO:0007265290.017
purine ribonucleotide catabolic processGO:00091541360.017
positive regulation of hydrolase activityGO:0051345860.017
single organism catabolic processGO:00447122830.017
proteolysisGO:00065081750.017
positive regulation of programmed cell deathGO:00430681570.017
b cell mediated immunityGO:001972440.017
transmission of nerve impulseGO:0019226420.017
regulation of purine nucleotide metabolic processGO:19005421150.017
ribonucleoside triphosphate catabolic processGO:00092031220.017
protein complex assemblyGO:00064612630.017
protein heterooligomerizationGO:0051291890.016
positive regulation of cell migrationGO:0030335960.016
cytosolic calcium ion homeostasisGO:00514801400.016
negative regulation of nucleic acid templated transcriptionGO:19035071170.016
positive regulation of transcription dna templatedGO:00458931970.016
Human
cellular catabolic processGO:00442482950.016
protein oligomerizationGO:00512591910.016
nucleoside metabolic processGO:00091161790.016
negative regulation of cellular protein metabolic processGO:00322691060.016
Human
regulation of transferase activityGO:00513381230.016
Human
negative regulation of gene expressionGO:00106291990.016
negative regulation of biosynthetic processGO:00098901680.016
multicellular organismal signalingGO:0035637440.016
divalent inorganic cation transportGO:00725111340.016
response to organophosphorusGO:00466831020.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
response to bacteriumGO:00096172000.016
response to molecule of bacterial originGO:00022371940.016
organic cyclic compound catabolic processGO:19013611750.016
cellular response to abiotic stimulusGO:0071214850.016
developmental growthGO:00485891000.015
ion homeostasisGO:00508012120.015
peptidyl tyrosine modificationGO:0018212720.015
metal ion homeostasisGO:00550651860.015
single organism intracellular transportGO:19025821660.015
Human
rhythmic processGO:00485111560.015
regulation of hormone levelsGO:00108171870.015
cellular nitrogen compound catabolic processGO:00442701630.015
regulation of neuron apoptotic processGO:0043523830.015
hematopoietic progenitor cell differentiationGO:000224420.015
cellular response to nitrogen compoundGO:19016992100.015
protein complex biogenesisGO:00702712630.015
regulation of protein kinase activityGO:00458591050.015
Human
nucleoside phosphate catabolic processGO:19012921400.015
positive regulation of locomotionGO:00400171020.015
regulation of cellular localizationGO:00603412630.015
regulation of response to woundingGO:1903034690.014
activation of immune responseGO:0002253260.014
ribonucleoside metabolic processGO:00091191740.014
reactive oxygen species metabolic processGO:0072593370.014
action potentialGO:0001508540.014
organonitrogen compound catabolic processGO:19015651790.014
small gtpase mediated signal transductionGO:0007264360.014
gastrulationGO:000736920.014
response to cytokineGO:00340972150.014
negative regulation of macromolecule biosynthetic processGO:00105581480.014
comma shaped body morphogenesisGO:007204920.014
heterocycle catabolic processGO:00467001670.014
response to corticosteroidGO:00319602350.014
regulation of anatomical structure morphogenesisGO:00226031410.014
negative regulation of phosphorus metabolic processGO:0010563800.013
Human
g protein coupled receptor signaling pathwayGO:00071862420.013
regulation of metal ion transportGO:00109591180.013
negative regulation of molecular functionGO:00440921330.013
Human
purine nucleoside metabolic processGO:00422781690.013
gonad developmentGO:00084061040.013
immune effector processGO:0002252530.013
regulation of small gtpase mediated signal transductionGO:0051056480.013
regulation of behaviorGO:0050795610.013
negative regulation of catalytic activityGO:00430861030.013
Human
glial cell differentiationGO:0010001650.013
immunoglobulin mediated immune responseGO:001606440.013
sex differentiationGO:00075481130.013
regulation of catabolic processGO:00098941130.013
regulation of cell motilityGO:20001451310.013
immune responseGO:00069551040.013
negative regulation of transportGO:00510511360.013
cytoplasmic transportGO:00164821150.013
Human
lymphocyte migrationGO:007267630.013
peptidyl tyrosine phosphorylationGO:0018108720.013
response to fatty acidGO:0070542650.013
nucleoside triphosphate metabolic processGO:00091411440.013
positive regulation of humoral immune responseGO:000292220.013
cell cycle checkpointGO:000007520.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
ensheathment of neuronsGO:0007272400.012
guanosine containing compound metabolic processGO:1901068740.012
defense response to gram negative bacteriumGO:005082930.012
regulation of protein phosphorylationGO:00019321830.012
Human
sequestering of metal ionGO:005123890.012
nucleobase containing compound catabolic processGO:00346551520.012
single organism behaviorGO:00447081300.012
organic hydroxy compound metabolic processGO:19016151150.012
reactive nitrogen species metabolic processGO:200105710.012
cellular response to peptideGO:19016531330.012
regulation of b cell differentiationGO:004557710.012
regulation of nucleotide catabolic processGO:0030811650.012
development of primary sexual characteristicsGO:00451371070.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
regulation of cell adhesionGO:0030155520.012
gamete generationGO:00072761240.012
muscle system processGO:00030121150.012
immune response regulating signaling pathwayGO:0002764190.012
response to insulinGO:00328681330.012
carbohydrate derivative catabolic processGO:19011361470.012
lipid metabolic processGO:00066292830.012
regulation of cytokine productionGO:0001817560.012
sequestering of calcium ionGO:005120880.012
response to hexoseGO:00097461440.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
vasculature developmentGO:0001944700.011
response to toxic substanceGO:00096361330.011
negative regulation of phosphate metabolic processGO:0045936800.011
Human
cellular response to external stimulusGO:00714961180.011
response to purine containing compoundGO:00140741260.011
response to vitaminGO:00332731310.011
growthGO:00400071650.011
guanosine containing compound catabolic processGO:1901069710.011
cellular response to lipopolysaccharideGO:0071222550.011
regulation of immune responseGO:0050776550.011
response to metal ionGO:00100382530.011
negative regulation of protein metabolic processGO:00512481140.011
Human
rho protein signal transductionGO:0007266110.011
epithelium developmentGO:0060429960.011
cellular response to mechanical stimulusGO:0071260480.011
glycosyl compound catabolic processGO:19016581260.011
gtp metabolic processGO:0046039720.011
positive regulation of protein kinase activityGO:0045860730.011
dna metabolic processGO:0006259960.011
Human
response to mechanical stimulusGO:00096121340.011
positive regulation of nucleotide metabolic processGO:0045981910.011
negative regulation of signal transductionGO:0009968830.011
macromolecule localizationGO:00330362520.011
Human
single organism cell adhesionGO:0098602460.011
gliogenesisGO:0042063930.011
organophosphate catabolic processGO:00464341480.011
single organismal cell cell adhesionGO:0016337420.011
cell part morphogenesisGO:00329901230.011
negative regulation of cell proliferationGO:00082851190.011
cell cycleGO:00070491010.011
Human
positive regulation of kinase activityGO:0033674770.011
regulation of response to external stimulusGO:00321011060.011
nuclear transportGO:0051169490.011
Human
response to campGO:0051591910.011
regulation of purine nucleotide catabolic processGO:0033121650.010
cation homeostasisGO:00550801950.010
embryonic axis specificationGO:000057810.010
sexual reproductionGO:00199531480.010
cytoskeleton organizationGO:00070101110.010
muscle structure developmentGO:0061061870.010
cellular response to oxidative stressGO:0034599760.010
cellular protein localizationGO:00346131220.010
Human
secretionGO:00469033070.010
nucleotide catabolic processGO:00091661390.010
protein complex subunit organizationGO:00718223020.010
regulation of immunoglobulin mediated immune responseGO:000288920.010
regulation of nucleoside metabolic processGO:0009118660.010
negative regulation of cellular component organizationGO:0051129830.010
reproductive structure developmentGO:00486081280.010
male gamete generationGO:0048232990.010
renal system developmentGO:0072001670.010
cell morphogenesis involved in differentiationGO:00009041190.010
cellular response to steroid hormone stimulusGO:0071383930.010
regulation of system processGO:00440572080.010
cell projection morphogenesisGO:00488581230.010
heart morphogenesisGO:000300730.010
response to oxidative stressGO:00069791860.010

Hhex disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
nervous system diseaseDOID:86300.016
eye diseaseDOID:561400.011
retinal diseaseDOID:567900.011
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011